CN115119848A - Disinfectant for livestock and poultry and preparation method thereof - Google Patents

Disinfectant for livestock and poultry and preparation method thereof Download PDF

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Publication number
CN115119848A
CN115119848A CN202111215671.6A CN202111215671A CN115119848A CN 115119848 A CN115119848 A CN 115119848A CN 202111215671 A CN202111215671 A CN 202111215671A CN 115119848 A CN115119848 A CN 115119848A
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parts
disinfectant
livestock
extract
compound
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CN202111215671.6A
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Chinese (zh)
Inventor
潘逢文
张松柏
杨洪战
刘浩
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Hunan Kunyuan Biotechnology Co ltd
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Hunan Kunyuan Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44Guanidine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02Amines; Quaternary ammonium compounds
    • A01N33/12Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/22Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/24Lauraceae [Laurel family], e.g. laurel, avocado, sassafras, cinnamon or camphor
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/28Myrtaceae [Myrtle family], e.g. teatree or clove
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/30Polygonaceae [Buckwheat family], e.g. red-knees or rhubarb

Abstract

The invention relates to the technical field of A01N, in particular to a disinfectant for livestock and poultry and a preparation method thereof. The disinfectant for livestock and poultry comprises the following preparation raw materials in parts by weight: 8-15 parts of double-chain quaternary ammonium salt compound, 20-30 parts of plant extract, 0.6-1.5 parts of biguanide compound, 0.05-0.8 part of acid compound, 8-15 parts of surfactant, 5-15 parts of alcohol-based compound and 55-70 parts of water; the disinfectant for livestock and poultry prepared by the invention has excellent bactericidal effect on various pathogenic bacteria, and the disinfectant for livestock and poultry obtained by the vegetation of the invention adopts plant extracts as raw materials, thus having the characteristics of low toxicity, safety and environmental protection.

Description

Disinfectant for livestock and poultry and preparation method thereof
Technical Field
The invention relates to the technical field of A01N, in particular to a disinfectant for livestock and poultry and a preparation method thereof.
Background
The Chinese patent with the patent application number of CN201610075150.8 discloses a compound disinfectant and application thereof, the disinfectant has the advantages of high efficiency, small corrosivity and the like, is used for disinfecting livestock and poultry environment, equipment and the like, has wide market prospect and value, but does not solve the technical problem of disinfection stability after long-time storage of the disinfectant.
Chinese patent with patent application number CN201710482464.4 discloses a novel veterinary compound disinfectant and a preparation method thereof, solves the problem of removing bad smell in livestock and poultry breeding places, is suitable for the field of veterinary disinfectant, but does not solve the technical problem of solving the disinfection stability of the disinfectant after long-time storage.
Disclosure of Invention
In order to solve the problems, the invention provides a disinfectant for livestock and poultry, which comprises the following raw materials in parts by weight: 8-15 parts of double-chain quaternary ammonium salt compound, 20-30 parts of plant extract, 0.6-1.5 parts of biguanide compound, 0.05-0.8 part of acid compound, 8-15 parts of surfactant, 5-15 parts of alcohol-based compound and 55-70 parts of water; the plant extract is one or more selected from rosemary essential oil, litsea cubeba oil, eucalyptus oil, cinnamon oil, eucommia ulmoides extract and magnolia officinalis extract.
Preferably, the double-chain quaternary ammonium salt compound is selected from one or more of dioctyl quaternary ammonium salt, didecyl quaternary ammonium salt, didodecyl quaternary ammonium salt or octyl decyl quaternary ammonium salt, didecyl dimethyl ammonium chloride, didecyl dimethyl ammonium bromide, dioctadecyl dimethyl ammonium chloride, didodecyl dimethyl ammonium chloride, dioctadecyl dimethyl ammonium chloride, didodecyl dimethyl ammonium bromide and dioctadecyl dimethyl ammonium bromide.
Preferably, the double-chain quaternary ammonium salt compound comprises didodecyl quaternary ammonium salt and dioctadecyl dimethyl ammonium chloride.
Preferably, the weight ratio of the didodecyl quaternary ammonium salt to the dioctadecyl dimethyl ammonium chloride is 1.5: 1.
Preferably, the biguanide compound is polyhexamethylene biguanide or a salt thereof.
Preferably, the biguanide compound is polyhexamethylene biguanide hydrochloride.
The applicant finds unexpectedly in experiments that when the polyhexamethylene biguanide hydrochloride is used in combination with the didodecyl quaternary ammonium salt, the dioctadecyl dimethyl ammonium chloride and the dodecyl dimethyl betaine, the good mutual synergistic effect is achieved, and the sterilization effect of the didodecyl quaternary ammonium salt, the dioctadecyl dimethyl ammonium chloride, the cinnamon oil, the eucommia ulmoides extract and the polygonum cuspidatum extract can be improved.
Preferably, the acid compound is an inorganic acid.
Preferably, the inorganic acid is phosphoric acid.
Preferably, the surfactant comprises an amphoteric surfactant and an anionic surfactant.
Preferably, the weight ratio of the amphoteric surfactant to the anionic surfactant is (1.5-3): 1.
Further, the weight ratio of the amphoteric surfactant to the anionic surfactant is 2: 1.
Preferably, the amphoteric surfactants include dodecyl dimethyl betaine and cocamidopropyl betaine.
Further, the weight ratio of the dodecyl dimethyl betaine to the cocamidopropyl betaine is 1: 1.
Preferably, the anionic surfactants include sodium alpha-alkenyl sulfonate and sodium lauryl sulfate.
Furthermore, the weight ratio of the alpha-sodium alkenyl sulfonate to the sodium dodecyl sulfate is 1 (2-3).
The CAS number of the alpha-alkenyl sodium sulfonate is 72674-05-6.
The cocamidopropyl betaine accounts for 35% by mass.
The cocamidopropyl betaine is purchased from Jinan Chengxuan chemical Co., Ltd, and the model is CAB-35.
The applicant unexpectedly found in experiments that when the amphoteric surfactant, the anionic surfactant and the double-chain quaternary ammonium salt compound are mixed and added into a raw material system of the disinfectant, the stability of the raw material system can be increased, and the disinfection effect of the disinfectant when the disinfectant is stored and used is improved, when the weight ratio of the mixture of the amphoteric surfactant, the anionic surfactant and the dioctadecyl dimethyl ammonium chloride is 1:1, the weight ratio of the amphoteric surfactant consisting of the dodecyl dimethyl betaine and the cocamidopropyl betaine to the anionic surfactant consisting of the alpha-sodium alkenyl sulfonate and the sodium dodecyl sulfate is (1.5-3):1, particularly when the weight ratio is 2:1, the dodecyl dimethyl betaine, the cocamidopropyl betaine, the alpha-sodium alkenyl sulfonate, the sodium dodecyl sulfate, the didodecyl quaternary ammonium salt and the dioctadecyl dimethyl ammonium chloride, when used together, the disinfectant for livestock and poultry not only has good sterilization effect and long-term disinfection stability, but also can soften the grease and oil stain in the livestock and poultry house, thoroughly disinfect the microorganisms contained in the grease and oil stain, and improve the sterilization effect.
Preferably, the plant extract is selected from one or more of rosemary oil, litsea cubeba oil, eucalyptus oil, cinnamon oil, eucommia ulmoides extract and magnolia officinalis extract.
Preferably, the weight ratio of the double-chain quaternary ammonium salt compound to the plant extract is 1: (1.5-3.5).
The applicant unexpectedly found in experiments that when the double-chain quaternary ammonium salt compound and the plant extract are used in combination, the weight ratio of the double-chain quaternary ammonium salt compound to the plant extract is 1: (1.5-3.5), especially the weight ratio of the double-chain quaternary ammonium salt compound to the plant extract is 1: (2.5), the bactericidal effect is good, and the probable reason is that the double-chain quaternary ammonium salt compound can change the permeability of cell membranes of bacteria, molds and viruses when contacting the bacteria, molds and viruses, so that active ingredients in the plant extract are improved to destroy protein molecules of the bacteria, molds and viruses, and the protein molecules lose the activity function, thereby causing the death of the protein molecules, and the bactericidal effect is promoted by the matching use of the double-chain quaternary ammonium salt compound.
The plant extract is a mixture of cinnamon oil, an eucommia bark extract and a giant knotweed rhizome extract, and the weight ratio of the cinnamon oil to the eucommia bark extract to the giant knotweed rhizome extract is (5-8) to (2-4) to 1.
Preferably, the weight ratio of the cinnamon oil to the eucommia ulmoides extract to the polygonum cuspidatum extract is (6-7) to (2.5-3.5) to 1.
The plant extract is used as the raw material component of the bactericide, so that the bactericide has an effect of environmental protection, and when the plant extract is used together with other raw materials in a bactericide raw material system, the bactericide has a synergistic effect, so that the disinfectant for livestock and poultry has a good bactericidal effect; the applicant finds that unexpectedly in experiments, a mixture of cinnamon oil, an eucommia ulmoides extract and a polygonum cuspidatum extract is added into a raw material system, when the weight ratio of the cinnamon oil to the eucommia ulmoides extract to the polygonum cuspidatum extract is (5-8): 2-4):1, and particularly the weight ratio of the cinnamon oil to the eucommia ulmoides extract to the polygonum cuspidatum extract is (6-7): 2.5-3.5):1, active ingredients in the cinnamon oil, the eucommia ulmoides extract and the polygonum cuspidatum extract can be mutually cooperated to destroy protein molecules in bacteria and viruses, so that the protein molecules lose active functions, the bacteria can be killed, the disinfection effect is thorough, and the sterilization effect of the disinfectant for livestock and poultry is improved.
Preferably, the acid compound is an inorganic acid.
Preferably, the alcohol-based compound is selected from one or more of methanol, ethanol, n-propanol, isopropanol, n-butanol and isobutanol.
Preferably, the alcohol-based compound is n-propanol.
A preparation method of the disinfectant for livestock and poultry comprises the following steps: adding 8-15 parts of double-chain quaternary ammonium salt compound, 20-30 parts of plant extract, 0.6-1.5 parts of biguanide compound, 0.05-0.8 part of acid compound, 8-15 parts of surfactant, 5-15 parts of alcohol-based compound and 55-70 parts of water into a stirring device for stirring to obtain the disinfectant for livestock and poultry.
Advantageous effects
The amphoteric surfactant composed of dodecyl dimethyl betaine and cocamidopropyl betaine, the anionic surfactant composed of alpha-sodium alkenyl sulfonate and sodium dodecyl sulfate and the double-chain quaternary ammonium salt compound are mixed and added into a raw material system of the disinfectant, the stability of the raw material system can be improved, and the disinfection effect of the disinfectant when the disinfectant is stored and used is improved.
When the double-chain quaternary ammonium salt compound and the plant extract are used in a matching way, the weight ratio of the double-chain quaternary ammonium salt compound to the plant extract is 1: (1.5-3.5), especially the weight ratio of the double-chain quaternary ammonium salt compound to the plant extract is 1: (2.5) the disinfectant for livestock and poultry has good bactericidal effect.
The method comprises the steps of adding a mixture of cinnamon oil, an eucommia ulmoides extract and a polygonum cuspidatum extract into a raw material system, wherein when the weight ratio of the cinnamon oil to the eucommia ulmoides extract to the polygonum cuspidatum extract is (5-8): (2-4):1, and particularly, the weight ratio of the cinnamon oil to the eucommia ulmoides extract to the polygonum cuspidatum extract is (6-7): (2.5-3.5):1, active ingredients in the cinnamon oil, the eucommia ulmoides extract and the polygonum cuspidatum extract can be mutually cooperated to destroy protein molecules in bacteria and viruses, so that the protein molecules lose activity, the bacteria and viruses are killed, the disinfection effect is thorough, and the sterilization effect of the disinfectant for livestock and poultry is improved.
The disinfectant for livestock and poultry prepared by the invention has excellent bactericidal effect on various pathogenic bacteria, and the disinfectant for livestock and poultry prepared by the invention selects plant extracts as raw materials, and has the characteristics of low toxicity, safety and environmental protection.
Detailed Description
Example 1
The disinfectant for livestock and poultry comprises the following preparation raw materials in parts by weight: 6.75 parts of didodecyl quaternary ammonium salt, 4.5 parts of dioctadecyl dimethyl ammonium chloride, 15.6 parts of cinnamon oil, 7.2 parts of eucommia bark extract, 2.4 parts of giant knotweed rhizome extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 4 parts of dodecyl dimethyl betaine, 4 parts of cocamidopropyl betaine, 1 part of alpha-alkenyl sodium sulfonate, 3 parts of lauryl sodium sulfate, 12 parts of n-propanol and 65 parts of water.
The cinnamon oil purchasing manufacturer is Shaanxi Murphy Biotechnology Co., Ltd, and the mass content is 99%.
The eucommia ulmoides extract purchasing manufacturer is Shanxi Hui Nentada Biotech Co.
The purchase manufacturer of the giant knotweed rhizome extract is Shaanxi Rivo Biotechnology Co., Ltd.
The CAS of the polyhexamethylene biguanide hydrochloride is 32289-58-0.
The weight content of the cocamidopropyl betaine is 35%.
The cocamidopropyl betaine is purchased from Jinan Chengxuan chemical Co., Ltd, and the model is CAB-35.
A preparation method of the disinfectant for livestock and poultry comprises the following steps: 6.75 parts of didodecyl quaternary ammonium salt, 4.5 parts of dioctadecyl dimethyl ammonium chloride, 15.6 parts of cinnamon oil, 7.2 parts of eucommia ulmoides extract, 2.4 parts of giant knotweed rhizome extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 4 parts of dodecyl dimethyl betaine, 4 parts of cocamidopropyl betaine, 1 part of alpha-alkenyl sodium sulfonate, 3 parts of lauryl sodium sulfate, 12 parts of n-propanol and 65 parts of water are added into a stirring device to be stirred, so that the disinfectant for livestock and poultry is obtained.
Example 2
The disinfectant for livestock and poultry comprises the following preparation raw materials in parts by weight: 8.6 parts of didodecyl quaternary ammonium salt, 5.8 parts of dioctadecyl dimethyl ammonium chloride, 13.02 parts of cinnamon oil, 6.5 parts of eucommia bark extract, 2.6 parts of giant knotweed rhizome extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 4.5 parts of dodecyl dimethyl betaine, 4.5 parts of cocamidopropyl betaine, 1 part of alpha-alkenyl sodium sulfonate, 2 parts of lauryl sodium sulfate, 12 parts of n-propanol and 65 parts of water.
The weight content of the cocamidopropyl betaine is 35%.
The cocamidopropyl betaine is purchased from Jinan Chengxuan chemical Co., Ltd, and the model is CAB-35.
The cinnamon oil purchasing manufacturer is Shaanxi Murphy Biotech limited and has the mass content of 99%.
The eucommia ulmoides extract purchasing manufacturer is Shanxi Hui Nentada Biotech Co., Ltd.
The purchase manufacturer of the giant knotweed rhizome extract is Shaanxi Rivo Biotechnology Co., Ltd.
The CAS of the polyhexamethylene biguanide hydrochloride is 32289-58-0.
A preparation method of the disinfectant for livestock and poultry comprises the following steps: 8.6 parts of didodecyl quaternary ammonium salt, 5.8 parts of dioctadecyl dimethyl ammonium chloride, 13.02 parts of cinnamon oil, 6.5 parts of eucommia ulmoides extract, 2.6 parts of giant knotweed rhizome extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 4.5 parts of dodecyl dimethyl betaine, 4.5 parts of cocamidopropyl betaine, 1 part of alpha-alkenyl sodium sulfonate, 2 parts of lauryl sodium sulfate, 12 parts of n-propanol and 65 parts of water are added into a stirring device to be stirred, so that the disinfectant for livestock and poultry is obtained.
Example 3
The disinfectant for livestock and poultry comprises the following preparation raw materials in parts by weight: 5.25 parts of didodecyl quaternary ammonium salt, 3.5 parts of dioctadecyl dimethyl ammonium chloride, 18.2 parts of cinnamon oil, 9.1 parts of eucommia bark extract, 2.6 parts of giant knotweed rhizome extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 4.5 parts of dodecyl dimethyl betaine, 4.5 parts of cocamidopropyl betaine, 1.5 parts of alpha-alkenyl sodium sulfonate, 4.5 parts of lauryl sodium sulfate, 12 parts of n-propanol and 65 parts of water.
The cinnamon oil purchasing manufacturer is Shaanxi Murphy Biotech limited and has the mass content of 99%.
The eucommia ulmoides extract purchasing manufacturer is Shanxi Hui Nentada Biotech Co.
The purchase manufacturer of the giant knotweed rhizome extract is Shaanxi Rivo Biotechnology Co., Ltd.
The CAS of the polyhexamethylene biguanide hydrochloride is 32289-58-0.
A preparation method of the disinfectant for livestock and poultry comprises the following steps: 5.25 parts of didodecyl quaternary ammonium salt, 3.5 parts of dioctadecyl dimethyl ammonium chloride, 18.2 parts of cinnamon oil, 9.1 parts of eucommia bark extract, 2.6 parts of giant knotweed rhizome extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 4.5 parts of dodecyl dimethyl betaine, 4.5 parts of cocamidopropyl betaine, 1.5 parts of alpha-alkenyl sodium sulfonate, 4.5 parts of lauryl sodium sulfate, 12 parts of n-propanol and 65 parts of water are added into a stirring device for stirring to obtain the disinfectant for livestock and poultry.
Example 4
The disinfectant for livestock and poultry comprises the following preparation raw materials in parts by weight: 6.75 parts of didodecyl quaternary ammonium salt, 4.5 parts of dioctadecyl dimethyl ammonium chloride, 7.2 parts of eucommia bark extract, 2.6 parts of giant knotweed rhizome extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 4 parts of dodecyl dimethyl betaine, 4 parts of cocamidopropyl betaine, 12 parts of n-propanol and 65 parts of water.
The cinnamon oil purchasing manufacturer is Shaanxi Murphy Biotech limited and has the mass content of 99%.
The eucommia ulmoides extract purchasing manufacturer is Shanxi Hui Nentada Biotech Co., Ltd.
The giant knotweed extract purchasing manufacturer is Shaanxi Rivo Biotechnology Co., Ltd.
The CAS of the polyhexamethylene biguanide hydrochloride is 32289-58-0.
The weight content of the cocamidopropyl betaine is 35%.
The cocamidopropyl betaine is purchased from Jinan Chengxuan chemical Co., Ltd, and the model is CAB-35.
A preparation method of the disinfectant for livestock and poultry comprises the following steps: adding 6.75 parts of didodecyl quaternary ammonium salt, 4.5 parts of dioctadecyl dimethyl ammonium chloride, 7.2 parts of eucommia bark extract, 2.6 parts of giant knotweed rhizome extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 4 parts of dodecyl dimethyl betaine, 4 parts of cocamidopropyl betaine, 12 parts of n-propanol and 65 parts of water into a stirring device, and stirring to obtain the disinfectant for livestock and poultry.
Example 5
The disinfectant for livestock and poultry comprises the following preparation raw materials in parts by weight: 6.75 parts of didodecyl quaternary ammonium salt, 4.5 parts of dioctadecyl dimethyl ammonium chloride, 15.6 parts of cinnamon oil, 2.4 parts of giant knotweed extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 12 parts of n-propanol and 65 parts of water.
The cinnamon oil purchasing manufacturer is Shaanxi Murphy Biotechnology Co., Ltd, and the mass content is 99%.
The eucommia ulmoides extract purchasing manufacturer is Shanxi Hui Nentada Biotech Co., Ltd.
The purchase manufacturer of the giant knotweed rhizome extract is Shaanxi Rivo Biotechnology Co., Ltd.
The CAS of the polyhexamethylene biguanide hydrochloride is 32289-58-0.
A preparation method of the disinfectant for livestock and poultry comprises the following steps: adding 6.75 parts of didodecyl quaternary ammonium salt, 4.5 parts of dioctadecyl dimethyl ammonium chloride, 15.6 parts of cinnamon oil, 2.4 parts of giant knotweed extract, 1 part of polyhexamethylene biguanide hydrochloride, 0.45 part of phosphoric acid, 12 parts of n-propanol and 65 parts of water into a stirring device, and stirring to obtain the disinfectant for livestock and poultry.
Performance test
The test method comprises the following steps: the disinfection test is carried out according to the suspension quantitative sterilization experiment in GB/T38502-2020 disinfectant laboratory sterilization effect test method.
The disinfectant prepared in the embodiment 1-5 with the mass concentration of 5% is respectively used for sterilizing staphylococcus aureus, escherichia coli and bacillus subtilis black variant spores after the disinfectant is stored for 0 day and 180 days, the sterilizing time is 4min, the sterilizing logarithm value is calculated after sterilization, and when the sterilizing logarithm value exceeds 7.6, the evaluation result is A, so that the effect of completely killing can be achieved; when the sterilization logarithm value is more than 5 and less than 7.6, the evaluation result is B, and the complete killing effect cannot be achieved; when the sterilization logarithm value is less than 5.0, the evaluation result is C, the standard requirement that the sterilization logarithm value is unqualified and is more than or equal to 5.0 in the laboratory sterilization effect test method of the disinfectant can not be met, and the test evaluation result is shown in table 1.
TABLE 1
Figure BDA0003310696520000071
Figure BDA0003310696520000081

Claims (10)

1. The disinfectant for livestock and poultry is characterized by comprising the following preparation raw materials in parts by weight: 8-15 parts of double-chain quaternary ammonium salt compound, 20-30 parts of plant extract, 0.6-1.5 parts of biguanide compound, 0.05-0.8 part of acid compound, 8-15 parts of surfactant, 5-15 parts of alcohol-based compound and 55-70 parts of water; the plant extract is one or more selected from rosemary oil, litsea cubeba oil, eucalyptus oil, cinnamon oil, eucommia ulmoides extract and magnolia officinalis extract.
2. The disinfectant for livestock and poultry according to claim 1, wherein said double-chain quaternary ammonium salt compound is selected from one or more of dioctyl quaternary ammonium salt, didecyl quaternary ammonium salt, didodecyl quaternary ammonium salt or octyldecyl quaternary ammonium salt, didecyl dimethyl ammonium chloride, didecyl dimethyl ammonium bromide, dioctadecyl dimethyl ammonium chloride, dioctadecyl dimethyl ammonium bromide, didodecyl dimethyl ammonium chloride, dioctadecyl dimethyl ammonium chloride, didodecyl dimethyl ammonium bromide, and dioctadecyl dimethyl ammonium bromide.
3. The disinfectant for livestock and poultry according to claim 1, wherein said biguanide compound is polyhexamethylene biguanide or a salt thereof.
4. The disinfectant for livestock and poultry according to any one of claims 1 to 3, wherein the plant extract is a mixture of cinnamon oil, eucommia bark extract and polygonum cuspidatum extract, and the weight ratio of cinnamon oil, eucommia bark extract and polygonum cuspidatum extract is (5-8): 2-4): 1.
5. The disinfectant for livestock and poultry according to claim 4, wherein the weight ratio of the cinnamon oil, the eucommia ulmoides extract and the polygonum cuspidatum extract is (6-7): (2.5-3.5): 1.
6. The disinfectant for livestock and poultry according to claim 1, wherein the weight ratio of the double-chain quaternary ammonium salt compound to the plant extract is 1: (1.5-3.5).
7. The disinfectant for livestock and poultry according to claim 1, wherein said surfactant comprises an amphoteric surfactant and an anionic surfactant.
8. The disinfectant for livestock and poultry according to claim 1, wherein said acid compound is an inorganic acid.
9. The disinfectant for livestock and poultry according to claim 1, wherein said alcohol-based compound is selected from one or more of methanol, ethanol, n-propanol, isopropanol, n-butanol, and isobutanol.
10. A method for preparing the disinfectant for livestock and poultry according to any one of claims 1 to 9, comprising the steps of: adding 8-15 parts of double-chain quaternary ammonium salt compound, 20-30 parts of plant extract, 0.6-1.5 parts of biguanide compound, 0.05-0.8 part of acid compound, 8-15 parts of surfactant, 5-15 parts of alcohol-based compound and 55-70 parts of water into a stirring device, and stirring to obtain the disinfectant for livestock and poultry.
CN202111215671.6A 2021-10-19 2021-10-19 Disinfectant for livestock and poultry and preparation method thereof Pending CN115119848A (en)

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