CN111418587A - Efficient household fabric disinfectant and preparation method thereof - Google Patents
Efficient household fabric disinfectant and preparation method thereof Download PDFInfo
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- CN111418587A CN111418587A CN202010395495.8A CN202010395495A CN111418587A CN 111418587 A CN111418587 A CN 111418587A CN 202010395495 A CN202010395495 A CN 202010395495A CN 111418587 A CN111418587 A CN 111418587A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/16—Heavy metals; Compounds thereof
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Abstract
The invention relates to the technical field of disinfectants, in particular to an efficient household fabric disinfectant and a preparation method thereof. The efficient household fabric disinfectant at least comprises the following components in parts by weight: 10-30 parts of quaternary ammonium salt compound, 5-20 parts of polyhexamethylene guanidine compound, 5-15 parts of humectant, 1-10 parts of emulsifier, 1-5 parts of antibacterial agent and 50-100 parts of water. The invention provides an efficient household fabric disinfectant, which has broad sterilization spectrum, good sterilization and disinfection effects on fungi, bacteria and the like, high sterilization speed, no drug resistance of germs and thorough sterilization; the safety is high, no toxicity or residue is caused, the skin is not damaged, and no side effect is caused; the fabric is convenient to use, washing-resistant, safe and environment-friendly, does not affect clothes, is suitable for treating various household fabrics, and has great popularization value and wide application prospect.
Description
Technical Field
The invention relates to the technical field of disinfectants, in particular to an efficient household fabric disinfectant and a preparation method thereof.
Background
Various germs in the environment affect the health of people, and especially clothes, bed sheets, quilt covers and the like are in direct contact with the human body for a long time, and the environment-friendly health-care quilt has a direct relation to the health of people. The clothes such as clothes, bed sheets, quilt covers and the like can cause mildew when being stored improperly, and in public places such as hotels, hospitals and the like, because the personnel flow frequency is high, if the clothes, the bed sheets, the quilt covers and the like are not disinfected, some germs can be infected. The cotton fabric can provide a carbon source and a nitrogen source for the growth of bacteria, and the cotton fabric is easy to be stained with excreta such as sweat, sebum and the like in the using process, and the excreta are good nutrient substances for the growth of the bacteria; meanwhile, because the temperature of the human body is suitable for the growth of bacteria, if a large amount of pathogenic bacteria are carried on the fabric, the bacteria can easily propagate in large quantity and invade the human body to cause diseases. Towels, sheets and the like used in public places such as hotels, bath centers and the like, clothes and the like worn by people when people go in and out of public places, and particularly textile accessories (gauzes, surgical towels), sheets, work clothes and the like used in the industries such as medical treatment, medicine, food and the like can be used as transmission media of bacteria to cause cross infection or bacterial pollution, so that the health level of medical treatment and health care is reduced. Therefore, how to effectively disinfect and sterilize the clothes of people arouses high attention of people in all circles and related health organizations.
At present, a few products for sterilizing and disinfecting fabrics exist, and certain limitations exist. Since the types of germs attached to clothes are very many, there are bacterial germs, fungal germs, viral germs, and the like. Due to the complexity and coexistence of these pathogens, it is often difficult to select an ideal disinfectant, especially when some bacterial pathogens and fungal pathogens are present, it is more difficult to find a disinfectant that is both fungicidal and bactericidal, because each disinfectant has its limitations, and because of the broad spectrum of pathogens that are targeted to the types of pathogens.
The disinfectant for treating fabrics of natural fabrics, textile fabrics, non-woven fabrics, clothes, bedding, household articles and the like has the advantages of safe use, broad antibacterial spectrum, excellent antibacterial and washing fastness and excellent discoloration resistance.
Disclosure of Invention
In order to solve the technical problems, the invention provides a high-efficiency household fabric disinfectant, which comprises the following components in parts by weight: 10-30 parts of quaternary ammonium salt compound, 5-20 parts of polyhexamethylene guanidine compound, 5-15 parts of humectant, 1-10 parts of emulsifier, 1-5 parts of antibacterial agent and 50-100 parts of water.
As a preferable technical scheme of the invention, the quaternary ammonium salt compound is long-chain quaternary ammonium salt containing 8-24 carbon atoms.
As a preferable technical solution of the present invention, the quaternary ammonium salt compound is at least one selected from the group consisting of dioctadecyldimethylammonium chloride, didecyldimethylammonium chloride, didodecyldimethylammonium bromide, dioctadecyldimethylammonium bromide, octyldecyldimethylammonium chloride, octyldodecyldimethylammonium bromide, octyldecyldimethylammonium bromide, dioctyldimethylammonium bromide, didecyldimethylammonium bromide, and C12-14-alkyldimethylethylbenzylammonium chloride.
As a preferable technical scheme, the quaternary ammonium salt compound is a combination of dioctadecyl dimethyl ammonium chloride and C12-14-alkyl dimethyl ethyl benzyl ammonium chloride, and the weight ratio is 1: (0.8-1.5).
In a preferred embodiment of the present invention, the polyhexamethylene guanidine compound is at least one selected from the group consisting of polyhexamethylene biguanide hydrochloride, polyhexamethylene guanidine stearate, polyhexamethylene guanidine propionate, polyhexamethylene guanidine phosphate, polyhexamethylene guanidine sulfate, and polyoxyalkylene guanidine hydrochloride.
As a preferable technical scheme of the invention, the weight ratio of the quaternary ammonium salt compound to the polyhexamethylene guanidine compound is (1-2): 1.
in a preferred embodiment of the present invention, the emulsifier is an anionic emulsifier and/or a nonionic emulsifier.
As a preferable technical scheme of the invention, the emulsifier is a combination of sodium dodecyl benzene sulfonate, polysorbate and polyoxyethylene ether, and the weight ratio is 1: 1: (1-5).
As a preferable technical scheme of the invention, the antibacterial agent is nano titanium dioxide.
The second aspect of the invention provides a preparation method of the household fabric disinfectant, which at least comprises the following steps:
(1) mixing the humectant, the emulsifier and water, and uniformly stirring;
(2) adding quaternary ammonium salt compound and polyhexamethylene guanidine compound, heating to 40-80 ℃ while stirring, and continuously stirring until the mixture is uniformly mixed;
(3) adding antibacterial agent, stirring, mixing, and cooling to room temperature.
Advantageous effects
The invention provides an efficient household fabric disinfectant, which has broad sterilization spectrum, good sterilization and disinfection effects on fungi, bacteria and the like, high sterilization speed, no drug resistance of germs and thorough sterilization; the safety is high, no toxicity or residue is caused, the skin is not damaged, and no side effect is caused; the fabric is convenient to use, washing-resistant, safe and environment-friendly, does not affect clothes, is suitable for treating various household fabrics, and has great popularization value and wide application prospect.
Detailed Description
The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.
The term "prepared from …" as used herein is synonymous with "comprising". The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.
The conjunction "consisting of …" excludes any unspecified elements, steps or components. If used in a claim, the phrase is intended to claim as closed, meaning that it does not contain materials other than those described, except for the conventional impurities associated therewith. When the phrase "consisting of …" appears in a clause of the subject matter of the claims rather than immediately after the subject matter, it defines only the elements described in the clause; other elements are not excluded from the claims as a whole.
When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.
The singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. "optional" or "any" means that the subsequently described event or events may or may not occur, and that the description includes instances where the event occurs and instances where it does not.
Approximating language, as used herein throughout the specification and claims, is intended to modify a quantity, such that the invention is not limited to the specific quantity, but includes portions that are literally received for modification without substantial change in the basic function to which the invention is related. Accordingly, the use of "about" to modify a numerical value means that the invention is not limited to the precise value. In some instances, the approximating language may correspond to the precision of an instrument for measuring the value. In the present description and claims, range limitations may be combined and/or interchanged, including all sub-ranges contained therein if not otherwise stated.
In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.
In order to solve the technical problems, the invention provides a high-efficiency household fabric disinfectant, which comprises the following components in parts by weight: 10-30 parts of quaternary ammonium salt compound, 5-20 parts of polyhexamethylene guanidine compound, 5-15 parts of humectant, 1-10 parts of emulsifier, 1-5 parts of antibacterial agent and 50-100 parts of water.
In a preferred technical scheme, the household fabric disinfectant comprises the following components in parts by weight: 24 parts of quaternary ammonium salt compound, 16 parts of polyhexamethylene guanidine compound, 12 parts of humectant, 8 parts of emulsifier, 3 parts of antibacterial agent and 80 parts of water.
Quaternary ammonium salt compound
In the invention, the quaternary ammonium salt compound is long-chain quaternary ammonium salt containing 8-24 carbon atoms.
In a preferred embodiment, the quaternary ammonium salt compound is selected from at least one of dioctadecyldimethylammonium chloride, didecyldimethylammonium chloride, didodecyldimethylammonium chloride, didecyldimethylammonium bromide, didodecyldimethylammonium bromide, dioctadecyldimethylammonium bromide, octyldecyldimethylammonium chloride, octyldodecyldimethylammonium bromide, octyldecyldimethylammonium bromide, dioctyldimethylammonium bromide, didecyldimethylammonium bromide, and C12-14-alkyldimethylethylbenzylammonium chloride.
In a more preferred embodiment, the quaternary ammonium salt compound is a combination of dioctadecyldimethylammonium chloride and C12-14-alkyldimethylethylbenzylammonium chloride in a weight ratio of 1: (0.8-1.5).
In a most preferred embodiment, the quaternary ammonium salt compound is a combination of dioctadecyldimethylammonium chloride and C12-14-alkyldimethylethylbenzylammonium chloride in a weight ratio of 1: 1.2.
eighteen doubleAlkyl dimethyl ammonium chloride
Dioctadecyldimethylammonium chloride is a chemical substance with a molecular formula of (C)18H37)2(CH3)2NCl。
In the present invention, the source of the dioctadecyldimethylammonium chloride is not particularly limited, and may be mentioned by the company Yongkus technologies, Inc. in Hubei.
C12-14-alkyl dimethyl ethyl benzyl ammonium chloride
The CAS number for C12-14-alkyldimethylethylbenzylammonium chloride is 85409-23-0.
In the present invention, the source of the C12-14-alkyldimethylethylbenzylammonium chloride is not particularly limited, and Hubei Jinleda chemical company, Ltd.
Polyhexamethylene guanidine compounds
In the present invention, the polyhexamethylene guanidine compound is at least one selected from the group consisting of polyhexamethylene biguanide hydrochloride, polyhexamethylene guanidine stearate, polyhexamethylene guanidine propionate, polyhexamethylene guanidine phosphate, polyhexamethylene guanidine sulfate, and polyoxyalkylene guanidine hydrochloride.
In a preferred embodiment, the polyhexamethylene guanidine compound is polyhexamethylene biguanide hydrochloride.
The polyhexamethylene biguanide hydrochloride is a chemical substance with a chemical formula of (C)8H17N5)n.xHCl。
In the present invention, the source of the polyhexamethylene biguanide hydrochloride is not particularly limited, and examples thereof include Jinzhou jiahe sandiskei science and technology development ltd.
In the invention, the weight ratio of the quaternary ammonium salt compound to the polyhexamethylene guanidine compound is (1-2): 1.
in a preferred embodiment, the weight ratio of the quaternary ammonium salt compound to the polyhexamethylene guanidine compound is 1.5: 1.
the inventor thinks that the invention produces the synergistic effect by the reasonable compounding of the quaternary ammonium salt compound and the polyhexamethylene guanidine compound, can obviously improve the sterilization effect of the disinfectant, particularly has good killing effect on pseudomonas aeruginosa, staphylococcus aureus, escherichia coli and other bacterial propagules and candida albicans, simultaneously prolongs the action time of the disinfectant on microorganisms, solves the problems that the polyhexamethylene guanidine salt has poor killing effect on fungi, mycobacteria, hydrophilic viruses and the like when being used alone, basically has no killing effect on bacterial spores, and only can inhibit the propagation of the bacterial spores, ensures that the prepared disinfectant can kill the bacterial spores under the normal temperature condition, effectively improves the sterilization and sterilization effects of the disinfectant, and enlarges the application range of the disinfectant. The inventor thinks that the possible reason is that guanidino in the polyhexamethylene guanidine salt has higher activity, the compound is electropositive, and after the compound is compounded with quaternary ammonium salt for use, the electropositivity of the disinfectant system can be further improved; because various bacteria and viruses are generally electronegative, after being adsorbed to the surfaces of bacterial bodies, quaternary ammonium salt and guanidine compounds can interact with negative charges on cytoplasmic membranes to change the permeability of bacterial cytoplasmic membranes, so that important enzymes and nutrient substances in the bacterial bodies are extravasated, the respiratory and glycolysis processes of pathogenic microorganisms are blocked, mycoprotein of the bacterial bodies is denatured, and water seeps into the bacterial bodies to crack or melt pathogens to die, so that the bactericidal action is presented, and the bacteria and the viruses cannot be split and reproduced and lose activity; meanwhile, the structure of the cell membrane can be collapsed to form a transmembrane pore, the cell membrane is broken to destroy the energy metabolism of the microorganism, and the activity of the bacterial virus is lost; even if bacteria and viruses are mutated, the polyhexamethylene guanidine compound can form a layer of film on the bacteria to seal the breathing channel of the microorganism, so that the microorganism is suffocated.
However, the inventor also finds that the quaternary ammonium salt compound and the polyhexamethylene guanidine compound adopted by the invention belong to long-chain cationic compounds, and the crystallization is easily generated among molecules under the low-temperature condition, so that the effective components are separated out, and the application range of the disinfectant is seriously influenced. The inventor unexpectedly discovers in the experimental process that the phenomenon of low-temperature crystallization of the effective components of the disinfectant can be effectively inhibited and the stability of the disinfectant under the low-temperature condition is improved by reasonably compounding dioctadecyl dimethyl ammonium bromide and C12-14-alkyl dimethyl ethyl benzyl ammonium chloride. The inventors consider that possible reasons are: c12-14-alkyl dimethyl ethyl benzyl ammonium chloride molecules can contain ethyl benzyl with larger volume, can increase the distance between molecules in a chain segment and reduce the acting force between molecules in the chain segment, thereby reducing the winding among the molecules; meanwhile, quaternary ammonium salts with different carbon chain lengths are compounded, and molecular chain segments with different lengths are mutually wound, wrapped and interwoven into a network structure, so that the stability of the disinfectant under a low-temperature condition is effectively improved, and the application range of the disinfectant under the low-temperature condition is expanded. Meanwhile, the ethyl benzyl in the C12-14-alkyl dimethyl ethyl benzyl ammonium chloride can ensure that the charges on the whole molecular structure are recombined and distributed, the electronegativity on the benzene ring is increased, the conjugation effect of the benzene ring is enhanced, and the low-temperature sterilization effect of the disinfectant is further enhanced.
Moisture-retaining agent
The moisturizer is a cosmetic raw material with the functions of moisturizing and repairing sebum membranes, and the raw material has a special molecular structure, can adsorb and retain moisture, and maintains the skin barrier function while maintaining the skin hydration.
In the present invention, the humectant is not particularly limited, and polyhydric alcohol-based humectants can be mentioned.
In a preferred embodiment, the polyhydric alcohol humectant is at least one selected from glycerin, butylene glycol, polyethylene glycol, propylene glycol, hexylene glycol, xylitol, polypropylene glycol, and sorbitol.
In a more preferred embodiment, the humectant is polyethylene glycol.
Polyethylene glycol
The polyethylene glycol is non-toxic, non-irritant, slightly bitter in taste, good in water solubility and good in compatibility with a plurality of organic matter components. They have excellent lubricity, moisture retention, dispersibility, adhesives, antistatic agents, softeners and the like, and are widely applied in the industries of cosmetics, pharmacy, chemical fibers, rubber, plastics, papermaking, paint, electroplating, pesticides, metal processing, food processing and the like.
In the present invention, the weight average molecular weight of the polyethylene glycol is 150-500.
In a preferred embodiment, the polyethylene glycol has a weight average molecular weight of 270-330.
In the present invention, the source of the polyethylene glycol is not particularly limited, and may be one of the specifications PEG200, PEG300, and PEG400 from southeast university chemical company, ltd; PEG300 is preferred.
The inventor finds that the proper amount of polyethylene glycol is added, so that the dissolubility of the quaternary ammonium salt compound in water can be improved, the sedimentation of antibacterial agent particles can be inhibited, the dispersity of the antibacterial agent particles is improved, and the dispersity of the antibacterial agent particles under low-temperature conditions is maintained. The inventors believe that the possible reason is that polyethylene glycol can adjust the viscosity of the disinfectant, lowering the freezing point of the disinfectant; the solution viscosity has certain influence on the sedimentation speed of the antibacterial agent particles; the higher the viscosity of the solution is, the lower the movement speed of suspended particles in water is, so that the collision probability among the particles is reduced, and the stability of the solution is improved; however, the viscosity of the aqueous solution is too high to facilitate the dispersion of the suspended particles. The inventor finds that the dispersity and stability of the effective components in the disinfectant under low temperature conditions can be obviously improved by adopting the polyethylene glycol with small molecular weight.
Emulsifier
The principle of action of the emulsifiers is that during the emulsification process, the dispersed phase is dispersed in the form of droplets (micron-sized) in a continuous phase, which reduces the interfacial tension of the components of the mixed system and forms a stronger film on the surface of the droplets or forms an electric double layer on the surface of the droplets due to the charge given by the emulsifiers, preventing the droplets from aggregating with each other, while maintaining a homogeneous emulsion.
In the present invention, the emulsifier is not particularly limited, and anionic emulsifier, cationic emulsifier, and nonionic emulsifier can be mentioned.
In a preferred embodiment, the emulsifier is an anionic emulsifier and/or a nonionic emulsifier.
In the present invention, the anionic emulsifier is not particularly limited, and fatty acid soap, alkyl sulfate, alkylbenzene sulfonate, phosphate, and the like can be mentioned.
In the present invention, the nonionic emulsifier is not particularly limited, and polyoxyethylene ether, polyoxypropylene ether, ethylene oxide-propylene oxide block copolymer, polyol fatty acid ester, polyvinyl alcohol and the like can be mentioned.
In a preferred embodiment, the emulsifier is a combination of sodium dodecylbenzene sulfonate, polysorbate and polyoxyethylene ether in a weight ratio of 1: 1: (1-5).
In a more preferred embodiment, the emulsifier is a combination of sodium dodecylbenzene sulfonate, polysorbate and polyoxyethylene ether in a weight ratio of 1: 1: 3.
sodium dodecyl benzene sulfonate
Sodium dodecyl benzene sulfonate, sodium didecyl benzene sulfonate, abbreviated as SDBS, white or light yellow powder or flake solid. Is difficult to volatilize and easy to dissolve in water, and is dissolved in water to form a semitransparent solution. Stable chemical properties to alkali, dilute acid and hard water.
In the present invention, the source of the sodium dodecylbenzenesulfonate is not particularly limited, and Zheng Zhou Tian Shu Shang Shu Kong Co.
Polysorbate ester
In the present invention, the source of the polysorbate is not particularly limited, and there may be mentioned Haian petrochemical plants of Jiangsu province, specifications T-20, T-40, T-60, T-80, etc.; t-60 is preferred.
Polyoxyethylene ethers
In the present invention, the polyoxyethylene ether is not particularly limited, and stearic acid polyoxyethylene ether, fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, acetylene glycol polyoxyethylene ether, oleyl alcohol polyoxyethylene ether, and the like can be mentioned.
In a preferred embodiment, the polyoxyethylene ether is alkylphenol polyoxyethylene ether.
In a more preferred embodiment, the alkylphenol ethoxylate is nonylphenol ethoxylate.
In the present invention, the source of the polyoxyethylene nonylphenol ether is not particularly limited, and may be referred to from chenchen taixin lanxing science and technology ltd, model number NP-10.
In the invention, the inventor adds a certain amount of anionic emulsifier to improve the dirt-removing capacity of the disinfectant on the fabric. However, the inventor finds that the polyhexamethylene guanidine salt compound and the quaternary ammonium salt compound have positive ion property, are difficult to be compatible with anionic surfactants and the like, and can generate flocculation when mixed; meanwhile, the intermiscibility of the polyhexamethylene guanidine salt compound and the anion surface activity causes the prepared disinfectant to have poor stability. The inventor finds that clear, transparent, uniform and stable compound can be obtained by reasonably compounding emulsifier polyoxyethylene sorbitan oleate and nonylphenol polyoxyethylene ether to emulsify and aid a disinfectant system. The inventors consider that the possible reason is that polyoxyethylene sorbitan oleate is an oil-in-water type emulsifier, nonylphenol polyoxyethylene ether is a water-in-oil type emulsifier, and the hydrophilic group and the hydrophobic group of the anionic surfactant are respectively combined with the periphery of the emulsifier to form a bridge, so that the emulsifying performance can be improved, the solubilization and dispersion effects can be achieved, a high-stability solution can be formed, and the problem that the bactericidal capacity of the quaternary ammonium salt compound is reduced in the presence of the nonionic surfactant polyoxyethylene sorbitan monooleate can be solved.
The inventor also finds that after a certain amount of sodium dodecyl benzene sulfonate is added into the disinfectant, the treated fabric has poor hand feeling, skin is irritated when being contacted with the disinfectant for a long time, an adsorption film is easily formed on the surface of the fabric and is remained on the fabric, and the adsorption film is not easily removed by water washing at low temperature. But after a certain amount of wolf nonionic emulsifier is compounded, the residue of the sodium dodecyl benzene sulfonate can be obviously reduced through the emulsification. Meanwhile, the quaternary ammonium salt compound and the polyhexamethylene guanidine compound belong to long-chain cationic compounds, and have good electrostatic property, color fastness and flexibility. The cationic groups adsorb fiber molecules in aqueous solution to form ionic bonds, and simultaneously, the cationic groups are condensed to form a film, so that the cationic groups are firmly combined with the fibers, the hand feeling of the treated fabric is improved, and the fabric is highly resistant to washing. The disinfectant can be used for disinfection treatment of natural fibers such as cotton, hemp, silk and wool, chemical fibers such as terylene, nylon, acrylic and viscose, and blended fabrics thereof.
Antibacterial agent
In the invention, the antibacterial agent is nano titanium dioxide.
In a preferred embodiment, the nano titanium dioxide is modified nano titanium dioxide.
In the invention, the preparation method of the modified nano titanium dioxide comprises the following steps: mixing titanium dioxide and absolute ethyl alcohol according to a mass ratio of 1: (20-60) adding the mixture into a container for ultrasonic treatment, and then mixing the titanium dioxide with the water according to the mass ratio of 1: (2-5): (1-3) sequentially adding ferric acetylacetonate and ferric trichloride, and continuing to perform ultrasonic treatment; heating the mixed solution after ultrasonic treatment to 50-90 ℃, stirring for 20-60min, then cooling to room temperature while stirring, finally adding the same volume of absolute ethyl alcohol into the mixed solution, centrifuging to remove supernatant, and drying to obtain the modified titanium dioxide.
In a preferred embodiment, the preparation method of the modified nano titanium dioxide comprises the following steps: mixing nano titanium dioxide and absolute ethyl alcohol according to a mass ratio of 1: 50, adding the mixture into a container for ultrasonic treatment, and then mixing the mixture according to the mass ratio of the nano titanium dioxide of 1: 3: 2, sequentially adding ferric acetylacetonate and ferric trichloride, and continuing to perform ultrasonic treatment; heating the mixed solution after the ultrasonic treatment to 70 ℃, stirring for 60min, then cooling to room temperature while stirring, finally adding the same volume of absolute ethyl alcohol into the mixed solution, centrifuging to remove supernatant, and drying to obtain the modified nano titanium dioxide.
In a more preferred embodiment, the nano titanium dioxide has a particle size of 10 to 100 nm.
In a most preferred embodiment, the nano-titania has a particle size of 30 nm.
In the present invention, the source of the nano titanium dioxide is not particularly limited, and there may be mentioned Shanghai ink advanced materials science and technology, Inc., model MG-Ti012, etc.
The inventor finds that the modified nano titanium dioxide adopted by the invention modifies the titanium dioxide by ferric ions in the experimental process, so that the light absorption capacity of the titanium dioxide is properly improved, and the dispersibility of the titanium dioxide in an aqueous solution is enhanced.
Water (W)
In the present invention, the water is not particularly limited, and deionized water, tap water, distilled water, etc. may be mentioned.
In a preferred embodiment, the water is deionized water.
The second aspect of the invention provides a preparation method of the household fabric disinfectant, which at least comprises the following steps:
(1) mixing the humectant, the emulsifier and water, and uniformly stirring;
(2) adding quaternary ammonium salt compound and polyhexamethylene guanidine compound, heating to 40-60 ℃ while stirring, and continuously stirring until the mixture is uniformly mixed;
(3) adding antibacterial agent, stirring, mixing, and cooling to room temperature.
The present invention will be specifically described below by way of examples. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention.
In addition, the starting materials used are all commercially available, unless otherwise specified.
Examples
Example 1
The embodiment 1 provides an efficient household fabric disinfectant, which comprises the following components in parts by weight: 24 parts of quaternary ammonium salt compound, 16 parts of polyhexamethylene guanidine compound, 12 parts of humectant, 8 parts of emulsifier, 3 parts of antibacterial agent and 80 parts of water.
The quaternary ammonium salt compound is a combination of dioctadecyl dimethyl ammonium chloride and C12-14-alkyl dimethyl ethyl benzyl ammonium chloride, and the weight ratio is 1: 1.2; the dioctadecyl dimethyl ammonium chloride is purchased from Yongkui technology Limited in Hubei; the C12-14-alkyldimethylethyl benzyl ammonium chloride was purchased from Hubei Jinleda chemical Co., Ltd.
The polyhexamethylene guanidine compound is polyhexamethylene biguanide hydrochloride and is purchased from Jinzhou Jiahe sandiskei science and technology development limited.
The humectant is polyethylene glycol, and is purchased from Nantong Guanzhu chemical Co., Ltd, and has the specification of PEG 300.
The emulsifier is a combination of sodium dodecyl benzene sulfonate, polysorbate and polyoxyethylene ether, and the weight ratio is 1: 1: 3; the sodium dodecyl benzene sulfonate is purchased from Zhengzhou Tianyu Shang Co Ltd; the polysorbate is purchased from Haian petrochemical plants of Jiangsu province and has the specification of T-60; the polyoxyethylene ether is nonylphenol polyoxyethylene ether, which is purchased from chengtain xinlan star science and technology limited company, model number emulsifier NP-10.
The antibacterial agent is modified nano titanium dioxide; the preparation method of the modified nano titanium dioxide comprises the following steps: mixing nano titanium dioxide and absolute ethyl alcohol according to a mass ratio of 1: 50, adding the mixture into a container for ultrasonic treatment, and then mixing the mixture according to the mass ratio of the nano titanium dioxide of 1: 3: 2, sequentially adding ferric acetylacetonate and ferric trichloride, and continuing to perform ultrasonic treatment; heating the mixed solution after ultrasonic treatment to 70 ℃, stirring for 60min, then cooling to room temperature while stirring, finally adding the same volume of absolute ethyl alcohol into the mixed solution, centrifuging to remove supernatant, and drying to obtain modified nano titanium dioxide; the nanometer titanium dioxide has a particle size of 30nm, and is available from Shanghai ink high-tech materials, Inc. under the model of MG-Ti 012.
The water is deionized water.
The preparation method of the household fabric disinfectant comprises the following steps:
(1) mixing the humectant, the emulsifier and water, and uniformly stirring;
(2) adding quaternary ammonium salt compound and polyhexamethylene guanidine compound, heating to 50 ℃ while stirring, and continuously stirring until the mixture is uniformly mixed;
(3) adding antibacterial agent, stirring, mixing, and cooling to room temperature.
Example 2
Embodiment 2 provides a high-efficiency household fabric disinfectant, which comprises the following components in parts by weight: 10 parts of quaternary ammonium salt compound, 5 parts of polyhexamethylene guanidine compound, 5 parts of humectant, 1 part of emulsifier, 1 part of antibacterial agent and 50 parts of water.
The quaternary ammonium salt compound is a combination of dioctadecyl dimethyl ammonium chloride and C12-14-alkyl dimethyl ethyl benzyl ammonium chloride, and the weight ratio is 1: 0.8; the dioctadecyl dimethyl ammonium chloride is purchased from Yongkui technology Limited in Hubei; the C12-14-alkyldimethylethyl benzyl ammonium chloride was purchased from Hubei Jinleda chemical Co., Ltd.
The polyhexamethylene guanidine compound is polyhexamethylene biguanide hydrochloride and is purchased from Jinzhou Jiahe sandiskei science and technology development limited.
The humectant is polyethylene glycol, and is purchased from Nantong Guanzhu chemical Co., Ltd, and has the specification of PEG 300.
The emulsifier is a combination of sodium dodecyl benzene sulfonate, polysorbate and polyoxyethylene ether, and the weight ratio is 1: 1: 1; the sodium dodecyl benzene sulfonate is purchased from Zhengzhou Tianyu Shang Co Ltd; the polysorbate is purchased from Haian petrochemical plants of Jiangsu province and has the specification of T-60; the polyoxyethylene ether is nonylphenol polyoxyethylene ether, which is purchased from chengtain xinlan star science and technology limited company, model number emulsifier NP-10.
The antibacterial agent is modified nano titanium dioxide; the preparation method of the modified nano titanium dioxide comprises the following steps: mixing nano titanium dioxide and absolute ethyl alcohol according to a mass ratio of 1: 20, adding the mixture into a container for ultrasonic treatment, and then mixing the mixture according to the mass ratio of the nano titanium dioxide of 1: 2: 1, sequentially adding ferric acetylacetonate and ferric trichloride, and continuing to perform ultrasonic treatment; heating the mixed solution after ultrasonic treatment to 50 ℃, stirring for 20min, then cooling to room temperature while stirring, finally adding the same volume of absolute ethyl alcohol into the mixed solution, centrifuging to remove supernatant, and drying to obtain modified nano titanium dioxide; the nanometer titanium dioxide has a particle size of 10nm, and is purchased from combined fertilizer Nayao nanotechnology development Co., Ltd, model ZH-TiO210 NR.
The water is deionized water.
The preparation method of the household fabric disinfectant comprises the following steps:
(1) mixing the humectant, the emulsifier and water, and uniformly stirring;
(2) adding quaternary ammonium salt compound and polyhexamethylene guanidine compound, heating to 50 ℃ while stirring, and continuously stirring until the mixture is uniformly mixed;
(3) adding antibacterial agent, stirring, mixing, and cooling to room temperature.
Example 3
Embodiment 3 provides a high-efficiency household fabric disinfectant, comprising the following components in parts by weight: 30 parts of quaternary ammonium salt compound, 20 parts of polyhexamethylene guanidine compound, 15 parts of humectant, 10 parts of emulsifier, 5 parts of antibacterial agent and 100 parts of water.
The quaternary ammonium salt compound is a combination of dioctadecyl dimethyl ammonium chloride and C12-14-alkyl dimethyl ethyl benzyl ammonium chloride, and the weight ratio is 1: 1.5; the dioctadecyl dimethyl ammonium chloride is purchased from Yongkui technology Limited in Hubei; the C12-14-alkyldimethylethyl benzyl ammonium chloride was purchased from Hubei Jinleda chemical Co., Ltd.
The polyhexamethylene guanidine compound is polyhexamethylene biguanide hydrochloride and is purchased from Jinzhou Jiahe sandiskei science and technology development limited.
The humectant is polyethylene glycol, and is purchased from Nantong Guanzhu chemical Co., Ltd, and has the specification of PEG 300.
The emulsifier is a combination of sodium dodecyl benzene sulfonate, polysorbate and polyoxyethylene ether, and the weight ratio is 1: 1: 5; the sodium dodecyl benzene sulfonate is purchased from Zhengzhou Tianyu Shang Co Ltd; the polysorbate is purchased from Haian petrochemical plants of Jiangsu province and has the specification of T-60; the polyoxyethylene ether is nonylphenol polyoxyethylene ether, which is purchased from chengtain xinlan star science and technology limited company, model number emulsifier NP-10.
The antibacterial agent is modified nano titanium dioxide; the preparation method of the modified nano titanium dioxide comprises the following steps: mixing nano titanium dioxide and absolute ethyl alcohol according to a mass ratio of 1: 60, adding the mixture into a container for ultrasonic treatment, and then mixing the mixture according to the mass ratio of the nano titanium dioxide of 1: 5: 3, sequentially adding ferric acetylacetonate and ferric trichloride, and continuing to perform ultrasonic treatment; heating the mixed solution after ultrasonic treatment to 90 ℃, stirring for 60min, then cooling to room temperature while stirring, finally adding the same volume of absolute ethyl alcohol into the mixed solution, centrifuging to remove supernatant, and drying to obtain modified nano titanium dioxide; the nanometer titanium dioxide has a particle size of 100nm, and is purchased from Shanghai ink high-tech materials, Inc., model ZH-TiO2100 NJ.
The water is deionized water.
The preparation method of the household fabric disinfectant comprises the following steps:
(1) mixing the humectant, the emulsifier and water, and uniformly stirring;
(2) adding quaternary ammonium salt compound and polyhexamethylene guanidine compound, heating to 50 ℃ while stirring, and continuously stirring until the mixture is uniformly mixed;
(3) adding antibacterial agent, stirring, mixing, and cooling to room temperature.
Example 4
Example 4 differs from example 1 in that the quaternary ammonium salt compound is dioctadecyldimethylammonium chloride.
Example 5
Example 5 differs from example 1 in that the quaternary ammonium salt compound is C12-14-alkyldimethylethylbenzyl.
Example 6
Example 6 differs from example 1 in that quaternary ammonium salt compounds are not included.
Example 7
Example 7 differs from example 1 in that the polyhexamethyleneguanidine compound is polyhexamethyleneguanidine propionate.
Example 8
Example 8 differs from example 1 in that polyhexamethyleneguanidine compounds are not included.
Example 9
Example 9 differs from example 1 in that the humectant is propylene glycol.
Example 10
Example 10 differs from example 1 in that the emulsifier is sodium dodecylbenzene sulfonate.
Example 11
Example 11 differs from example 1 in that the emulsifier is a combination of sodium dodecylbenzene sulphonate and polysorbate in a weight ratio of 1: 1.
example 12
Example 12 differs from example 1 in that the emulsifier is a combination of sodium dodecylbenzene sulfonate and polyoxyethylene ether in a weight ratio of 1: 3.
example 13
Example 13 differs from example 1 in that the antimicrobial agent is nano titanium dioxide having a particle size of 30nm, which is available from Shanghai ink advanced materials science and technology, Inc. under model MG-Ti 012.
Performance testing
1. Disinfection Performance
The cloth pieces with the same material and size are respectively treated by escherichia coli (ATCC 25922), staphylococcus aureus (ATCC6538), candida albicans (ATCC 10231), pseudomonas aeruginosa (ATCC 27853) and bacillus subtilis (ATCC 9372), then the cloth pieces are respectively put into the disinfectant prepared in the embodiments 1-13 of the invention for 5 minutes, and the sterilization rates of the disinfectant provided by the embodiments on the escherichia coli, the staphylococcus aureus, the candida albicans, the pseudomonas aeruginosa and the bacillus subtilis in the cloth pieces are calculated and recorded in the table 1.
TABLE 1 results of the bactericidal efficacy test of the disinfectants provided in examples 1-13
2. Stability of
The disinfectant provided in the examples was placed in an incubator at-10 ℃ and left under these conditions for 6 months, and after 1, 3, and 6 months, the disinfectant was observed for abnormalities such as turbidity, precipitation, and the like, and recorded in table 2.
TABLE 2 stability test results for disinfectants provided in the examples
The foregoing examples are merely illustrative and serve to explain some of the features of the method of the present invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.
Claims (10)
1. The efficient household fabric disinfectant is characterized by comprising the following components in parts by weight: 10-30 parts of quaternary ammonium salt compound, 5-20 parts of polyhexamethylene guanidine compound, 5-15 parts of humectant, 1-10 parts of emulsifier, 1-5 parts of antibacterial agent and 50-100 parts of water.
2. The disinfectant for household fabrics according to claim 1, wherein the quaternary ammonium salt compound is a long-chain quaternary ammonium salt containing 8-24 carbon atoms.
3. The disinfectant for household fabrics according to claim 2, wherein said quaternary ammonium salt compound is selected from at least one of dioctadecyldimethylammonium chloride, didodecyldimethylammonium bromide, dioctadecyldimethylammonium bromide, octyldecyldimethylammonium chloride, octyldodecyldimethylammonium bromide, octyldecyldimethylammonium bromide, dioctyldimethylammonium bromide, didecyldimethylammonium bromide, and C12-14-alkyldimethylethylbenzylammonium chloride.
4. The disinfectant for household fabrics as claimed in claim 3, wherein said quaternary ammonium salt compound is a combination of dioctadecyldimethylammonium chloride and C12-14-alkyldimethylethylbenzylammonium chloride in a weight ratio of 1: (0.8-1.5).
5. The home fabric disinfectant according to claim 1, wherein said polyhexamethylene guanidine compound is selected from at least one of polyhexamethylene biguanide hydrochloride, polyhexamethylene guanidine stearate, polyhexamethylene guanidine propionate, polyhexamethylene guanidine phosphate, polyhexamethylene guanidine sulfate and polyoxyalkyleneguanidine hydrochloride.
6. The disinfectant for household fabrics according to any one of claims 1 to 5, wherein the weight ratio of the quaternary ammonium salt compound to the polyhexamethylene guanidine compound is (1-2): 1.
7. the home fabric disinfectant according to claim 1, wherein said emulsifier is an anionic emulsifier and/or a non-ionic emulsifier.
8. The disinfectant for household fabrics as claimed in claim 7, wherein the emulsifier is a combination of sodium dodecylbenzene sulfonate, polysorbate and polyoxyethylene ether in a weight ratio of 1: 1: (1-5).
9. The home fabric sanitizer according to claim 1, wherein the antimicrobial agent is nano titanium dioxide.
10. A method of preparing a household fabric sanitizer according to any one of claims 1 to 9 comprising at least the steps of:
(1) mixing the humectant, the emulsifier and water, and uniformly stirring;
(2) adding quaternary ammonium salt compound and polyhexamethylene guanidine compound, heating to 40-60 ℃ while stirring, and continuously stirring until the mixture is uniformly mixed;
(3) adding antibacterial agent, stirring, mixing, and cooling to room temperature.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115119848A (en) * | 2021-10-19 | 2022-09-30 | 湖南坤源生物科技有限公司 | Disinfectant for livestock and poultry and preparation method thereof |
| CN115450043A (en) * | 2022-08-29 | 2022-12-09 | 苍南宝盛纺织有限公司 | Acrylic fiber blended wool yarn and preparation method thereof |
| CN116035027A (en) * | 2023-01-11 | 2023-05-02 | 成都飞凡微盾生物科技有限公司 | Fabric disinfection and antibiosis finishing liquid and preparation method thereof |
-
2020
- 2020-05-12 CN CN202010395495.8A patent/CN111418587A/en not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115119848A (en) * | 2021-10-19 | 2022-09-30 | 湖南坤源生物科技有限公司 | Disinfectant for livestock and poultry and preparation method thereof |
| CN115450043A (en) * | 2022-08-29 | 2022-12-09 | 苍南宝盛纺织有限公司 | Acrylic fiber blended wool yarn and preparation method thereof |
| CN115450043B (en) * | 2022-08-29 | 2024-04-09 | 苍南宝盛纺织有限公司 | Acrylic fiber blended wool yarn and preparation method thereof |
| CN116035027A (en) * | 2023-01-11 | 2023-05-02 | 成都飞凡微盾生物科技有限公司 | Fabric disinfection and antibiosis finishing liquid and preparation method thereof |
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