CN107372681A - A kind of novel veterinary compound disinfectant and preparation method thereof - Google Patents
A kind of novel veterinary compound disinfectant and preparation method thereof Download PDFInfo
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- CN107372681A CN107372681A CN201710482464.4A CN201710482464A CN107372681A CN 107372681 A CN107372681 A CN 107372681A CN 201710482464 A CN201710482464 A CN 201710482464A CN 107372681 A CN107372681 A CN 107372681A
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- quaternary ammonium
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/06—Oxygen or sulfur directly attached to a cycloaliphatic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/36—Rutaceae [Rue family], e.g. lime, orange, lemon, corktree or pricklyash
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/40—Liliopsida [monocotyledons]
- A01N65/42—Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/40—Liliopsida [monocotyledons]
- A01N65/44—Poaceae or Gramineae [Grass family], e.g. bamboo, lemon grass or citronella grass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
- A61L9/013—Deodorant compositions containing animal or plant extracts, or vegetable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
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- Biotechnology (AREA)
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- Pest Control & Pesticides (AREA)
- Botany (AREA)
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Abstract
The invention provides a kind of novel veterinary compound disinfectant and preparation method thereof, the novel veterinary compound disinfectant is made up of the component of following percentage by weight：Bamboo extractive 1 3%, yucca extract 0.5 2%, the alcohol 0.2 0.5% of O cymenes 5, lemon 0.4 1.2%, biguanides 0.2 0.5%, single-stranded quaternary ammonium salt 5 10%, double-chain quaternary ammonium salt 3 6%, ethanol 8 15%, surplus are deionized water；Animal compound disinfectant obtained by the present invention has excellent bactericidal effect, and agent low toxicity, safety and environmental protection to various pathogens；On this basis, there is peculiar fragrance, can effectively remove the bad smell in livestock and poultry cultivation place, product is stable, can preserve for a long time.
Description
Technical field
The present invention relates to disinfectant for animals field, and in particular to a kind of novel veterinary compound disinfectant and preparation method thereof.
Background technology
Sterilization refers to remove or kill livestock and poultry body surface and its existence with suitable method according to different production links, object
Pathogenic microorganism and other harmful microorganisms in environment.Under the higher and higher trend of current intensive degree, farm is cultivated
Disease incidence becomes increasingly complex, and animal epidemic preventing and treating problem is very prominent.Scale livestock farming epidemic disease be often it is more because
The result of plain comprehensive function, but wherein it is most important be due to pathogenic microorganism in external environment intrusion and diffusion or field in move
Caused by thing microbiological contamination itself spreads.Effective sterilization is to prevent and reduce the pathogen in plant's environment, is cut
Disconnected epidemic disease route of transmission, one of prevention and the important measures of control plant infectious disease.
With food-safety problem getting worse, consumer has been increasingly turned to the demand of animal product from scalar type
Mass type, the limitation to animal-use drug are more and more stricter.Therefore, thorough, specification sterilization will turn into a kind of most effective, most convenient
Prevention and control disease means.Currently, Chinese aquaculture is also just thinking that scale strides forward, and how to carry out plant's cause of disease
The purification of microorganism is an extremely important scientific research and puts into practice direction.The scientific development and reasonable utilization of disinfectant are to plant
Purification work serve key effect, therefore it is that inevitable development becomes to develop less toxic, green, efficient compound disinfectant
Gesture.
The content of the invention
It is an object of the invention to provide a kind of novel veterinary compound disinfectant and preparation method thereof, obtained is for animals multiple
Square disinfectant has excellent bactericidal effect, and animal compound disinfectant of the present invention low toxicity, safety and environmental protection to various pathogens, fits
For popularization and application.
To realize object above, the present invention is achieved by the following technical programs：
A kind of novel veterinary compound disinfectant, is made up of the component of following percentage by weight：Bamboo extractive 1-3%, silk
It is blue extract 0.5-2%, O- cymene -5- alcohol 0.2-0.5%, lemon 0.4-1.2%, biguanides 0.2-0.5%, single-stranded
Quaternary ammonium salt 5-10%, double-chain quaternary ammonium salt 3-6%, ethanol 8-15%, surplus are deionized water.
Preferably, the novel veterinary compound disinfectant is made up of the component of following percentage by weight：Bamboo extractive
2%th, yucca extract 1.5%, O- cymene -5- alcohol 0.35%, lemon 1%, biguanides 3%, single-stranded quaternary ammonium salt 8%,
Double-chain quaternary ammonium salt 4%, ethanol 12%, surplus are deionized water.
Preferably, the biguanides is PHMB or its salt.
Preferably, the single-stranded quaternary ammonium salt is myristyl benzyl dimethyl ammonium chloride, dodecyl dimethyl benzyl bromide a-bromotoluene
Change one kind in ammonium, dodecyl benzyl dimethyl ammonium chloride.
Preferably, the double-chain quaternary ammonium salt is dioctadecyl dimethyl ammonium chloride or 2- (2- phenoxy groups) ethyl
Trimethyl ammonium chloride；More preferably double-chain quaternary ammonium salt is 2- (2- phenoxy groups) ethyl-trimethyl salmiac.
The preparation method of novel veterinary compound disinfectant of the present invention, comprises the following steps：Each raw material is weighed by weight ratio；
O- cymene -5- alcohol, lemon are added into ethanol, stirred evenly, add deionized water, sequentially added after stirring evenly biguanides,
Single-stranded quaternary ammonium salt, double-chain quaternary ammonium salt, bamboo extractive, yucca extract, it is stirring while adding, until solution is clarified, filtered, filling
Dress, is produced.
The beneficial effects of the invention are as follows：
Bamboo extractive in the present invention, it contains Flavonoids material, and bamboo-leaves flavones to staphylococcus aureus,
Escherichia coli, streptococcus, MRSE are respectively provided with different degrees of inhibitory action, particularly have to Escherichia coli well
Inhibitory action, while bamboo-leaves flavones are safe and non-toxic, environmentally friendly.Bamboo extractive has unique delicate fragrance, makes the taste of disinfectant more
Add smelling good.The yucca extract of addition is mainly used in carrying out deodorization to ambient environment during sterilization, because yucca
Extract has very strong suction-operated, and rising it is dense can to reduce its directly in conjunction with pernicious gases such as ammonia, hydrogen sulfide and methyl indols
Degree, it is also with certain sterilizing effect on this basis.
Animal compound disinfectant of the present invention adds single-stranded quaternary ammonium salt, double-chain quaternary ammonium salt, biguanides simultaneously in thimerosal, and three
Kind material can act synergistically, and can further strengthen the disinfective action of disinfectant, add bamboo extractive, yucca extract, lemon
Lemon essential oil and ethanol, make effectively improving for disinfectant, and bactericidal range is wider.And add on this basis a small amount of
O- cymene -5- alcohol, then can make the bactericidal effect of disinfectant reach optimal, in the case where dilution factor is 3000 times, to golden yellow
Color staphylococcus, Escherichia coli, chain pasteurella multocida, the sterilizing rate of hemolytic streptococcus can reach more than 99.99%.
Animal compound disinfectant of the present invention has peculiar fragrance, can had on the basis of with excellent disinfection effect
Effect removes the bad smell in livestock and poultry cultivation place, and disinfectant for animals of the present invention is sufficiently stable, can preserve for a long time, prepare and
All it is not required to carry out pH value regulation during use, it is practical and convenient.
Embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention,
Technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is the present invention one
Divide embodiment, rather than whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art are not making
The every other embodiment obtained under the premise of creative work, belongs to the scope of protection of the invention.
Embodiment 1：
A kind of novel veterinary compound disinfectant, is made up of the component of following percentage by weight：Bamboo extractive 2%, yucca
Extract 1.5%, O- cymene -5- alcohol 0.35%, lemon 1%, PHMB hydrochloride 3%, myristyl two
Methyl-benzyl ammonium chloride 8%, 2- (2- phenoxy groups) ethyl-trimethyl salmiac salt 4%, ethanol 12%, surplus for go from
Sub- water.
Embodiment 2：
A kind of novel veterinary compound disinfectant, is made up of the component of following percentage by weight：Bamboo extractive 3%, yucca
Extract 0.5%, O- cymene -5- alcohol 0.4%, lemon 0.8%, PHMB 0.2%, dodecyl dimethyl
Benzyl ammonium chloride 8%, 2- (2- phenoxy groups) ethyl-trimethyl salmiac 5%, ethanol 15%, surplus are deionized water.
Embodiment 3：
A kind of novel veterinary compound disinfectant, is made up of the component of following percentage by weight：Bamboo extractive 1.5%, silk
Blue extract 2%, O- cymene -5- alcohol 0.5%, lemon 1.2%, PHMB hydrochloride 0.5%, dodecyl
Dimethylbenzyl ammonium bromide 5%, dioctadecyl dimethyl ammonium chloride 6%, ethanol 12%, surplus are deionized water.
Embodiment 4：
A kind of novel veterinary compound disinfectant, is made up of the component of following percentage by weight：Bamboo extractive 1%, yucca
Extract 1%, O- cymene -5- alcohol 0.2%, lemon 0.4%, PHMB 0.3%, myristalkonium
Ammonium chloride 10%, 2- (2- phenoxy groups) ethyl-trimethyl salmiac 3%, ethanol 8%, surplus are deionized water.
Embodiment 5：
A kind of novel veterinary compound disinfectant, is made up of the component of following percentage by weight：Bamboo extractive 2.5%, silk
Blue extract 1%, O- cymene -5- alcohol 0.4%, lemon 0.7%, PHMB 0.5%, dodecyl dimethyl
Benzylphosphonium Bromide ammonium 5%, 2- (2- phenoxy groups) ethyl-trimethyl salmiac 4%, ethanol 14%, surplus are deionized water.
Embodiment 6：
A kind of novel veterinary compound disinfectant, is made up of the component of following percentage by weight：Bamboo extractive 1%, yucca
Extract 2%, O- cymene -5- alcohol 0.5%, lemon 1%, PHMB 0.4%, myristyl benzyl dimethyl
Ammonium chloride 8%, dioctadecyl dimethyl ammonium chloride 6%, ethanol 10%, surplus are deionized water.
The preparation method of novel veterinary compound disinfectant, comprises the following steps in 1-6 of the embodiment of the present invention：By weight ratio
Weigh each raw material；O- cymene -5- alcohol, lemon are added into ethanol, stirred evenly, adds deionized water, after stirring evenly successively
Biguanides, single-stranded quaternary ammonium salt, double-chain quaternary ammonium salt, bamboo extractive, yucca extract are added, it is stirring while adding, until solution is clear
Clearly, it is filtered, filling, produce.
The performance test of animal compound disinfectant of the present invention：
1st, test method
With reference to the Ministry of Agriculture《Disinfectant for animals qualification test technical specification》Method is tested, and is quantified using bacterial suspension
Method.
2nd, test strain：Including Escherichia coli, staphylococcus aureus, bacillus cereus.
3rd, various test strains are sterilized using the disinfectant of different solubility, sterilizing time 4min, counted after sterilization
Calculate sterilizing rate.
4th, killing result of the test of the animal compound disinfectant in 1-2 of the embodiment of the present invention to bacterial strain is as shown in table 1：
Killing result of the test of the animal compound disinfectant of the present invention of table 1 to bacterial strain
As shown in Table 1, animal compound disinfectant of the present invention to Escherichia coli 8099, staphylococcus aureus ATCC6538,
Bacillus cereus SSI C1/1 are in the case of larger extension rate, still with excellent bactericidal effect, and this hair
Bright animal compound disinfectant low toxicity, safety and environmental protection, suitable for popularization and application.
The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although with reference to the foregoing embodiments
The present invention is described in detail, it will be understood by those within the art that：It still can be to foregoing each implementation
Technical scheme described in example is modified, or carries out equivalent substitution to which part technical characteristic；And these modification or
Replace, the essence of appropriate technical solution is departed from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (9)
1. a kind of novel veterinary compound disinfectant, it is characterised in that be made up of the component of following percentage by weight：Bamboo extractive
1-3%, yucca extract 0.5-2%, O- cymene -5- alcohol 0.2-0.5%, lemon 0.4-1.2%, biguanides 0.2-
0.5%th, single-stranded quaternary ammonium salt 5-10%, double-chain quaternary ammonium salt 3-6%, ethanol 8-15%, surplus are deionized water.
2. novel veterinary compound disinfectant according to claim 1, it is characterised in that by the component of following percentage by weight
Composition：Bamboo extractive 2%, yucca extract 1.5%, O- cymene -5- alcohol 0.35%, lemon 1%, biguanides 3%,
Single-stranded quaternary ammonium salt 8%, double-chain quaternary ammonium salt 4%, ethanol 12%, surplus are deionized water.
3. novel veterinary compound disinfectant according to claim 1, it is characterised in that the biguanides is that polyhexamethylene is double
Guanidine or its salt.
4. novel veterinary compound disinfectant according to claim 1, it is characterised in that the single-stranded quaternary ammonium salt is the tetradecane
One kind in base dimethyl benzyl ammonium chloride, dodecyl dimethyl benzyl ammonium bromide, dodecyl benzyl dimethyl ammonium chloride.
5. novel veterinary compound disinfectant according to claim 1, it is characterised in that the double-chain quaternary ammonium salt is double 18
Alkyl dimethyl ammonium chloride or 2- (2- phenoxy groups) ethyl-trimethyl salmiac.
6. novel veterinary compound disinfectant according to claim 5, it is characterised in that the double-chain quaternary ammonium salt is 2- (2-
Phenoxy group) ethyl-trimethyl salmiac.
7. the preparation method of the novel veterinary compound disinfectant according to claim any one of 1-6, it is characterised in that including
Following steps：Each raw material is weighed by weight ratio；O- cymene -5- alcohol, lemon are added into ethanol, stirred evenly, is added
Deionized water, biguanides, single-stranded quaternary ammonium salt, double-chain quaternary ammonium salt, bamboo extractive, yucca extract, side are sequentially added after stirring evenly
Edged stirs, until solution is clarified, it is filtered, filling, produce.
Caused a disease carefully 8. the novel veterinary compound disinfectant according to claim any one of 1-6 is killed in non-therapeutic destination
Application in bacterium.
9. application according to claim 7, it is characterised in that the malignant bacteria is staphylococcus aureus, large intestine bar
Bacterium, hemolytic streptococcus, chain pasteurella multocida and bacillus cereus.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710482464.4A CN107372681B (en) | 2017-06-22 | 2017-06-22 | Novel veterinary compound disinfectant and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710482464.4A CN107372681B (en) | 2017-06-22 | 2017-06-22 | Novel veterinary compound disinfectant and preparation method thereof |
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| CN107372681A true CN107372681A (en) | 2017-11-24 |
| CN107372681B CN107372681B (en) | 2020-05-08 |
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ID=60332741
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108294069A (en) * | 2018-02-07 | 2018-07-20 | 合肥华盖生物科技有限公司 | A kind of disinfectant for animals and preparation method thereof |
| CN111096340A (en) * | 2019-12-02 | 2020-05-05 | 安徽启威生物科技有限公司 | Disinfectant concentrated solution for pet hospitals and preparation method thereof |
| CN111466416A (en) * | 2020-04-20 | 2020-07-31 | 重庆森盟新能源开发有限公司 | Composite disinfectant using photocatalysis technology |
| CN111789796A (en) * | 2020-04-28 | 2020-10-20 | 广东分子态生物股份有限公司 | Disinfectant with liposome-encapsulated bactericidal component and preparation method thereof |
| CN115119848A (en) * | 2021-10-19 | 2022-09-30 | 湖南坤源生物科技有限公司 | Disinfectant for livestock and poultry and preparation method thereof |
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| CN104886186A (en) * | 2015-05-14 | 2015-09-09 | 青岛国航祥玉技术服务有限公司 | Efficient bactericidal disinfectant for livestock breeding house |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104886186A (en) * | 2015-05-14 | 2015-09-09 | 青岛国航祥玉技术服务有限公司 | Efficient bactericidal disinfectant for livestock breeding house |
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| 武深树: "《畜禽粪便污染防治技术》", 31 December 2014, 湖南科学技术出版社 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108294069A (en) * | 2018-02-07 | 2018-07-20 | 合肥华盖生物科技有限公司 | A kind of disinfectant for animals and preparation method thereof |
| CN111096340A (en) * | 2019-12-02 | 2020-05-05 | 安徽启威生物科技有限公司 | Disinfectant concentrated solution for pet hospitals and preparation method thereof |
| CN111466416A (en) * | 2020-04-20 | 2020-07-31 | 重庆森盟新能源开发有限公司 | Composite disinfectant using photocatalysis technology |
| CN111789796A (en) * | 2020-04-28 | 2020-10-20 | 广东分子态生物股份有限公司 | Disinfectant with liposome-encapsulated bactericidal component and preparation method thereof |
| CN115119848A (en) * | 2021-10-19 | 2022-09-30 | 湖南坤源生物科技有限公司 | Disinfectant for livestock and poultry and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN107372681B (en) | 2020-05-08 |
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