CN103891772A - Compound sterilizing agent - Google Patents
Compound sterilizing agent Download PDFInfo
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- CN103891772A CN103891772A CN201410160247.XA CN201410160247A CN103891772A CN 103891772 A CN103891772 A CN 103891772A CN 201410160247 A CN201410160247 A CN 201410160247A CN 103891772 A CN103891772 A CN 103891772A
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- iodine
- dimethyl ammonium
- sterilizing agent
- ammonium chloride
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Abstract
The invention provides a compound sterilizing agent. The compound sterilizing agent comprises the following components in percentage by weight: 10%-75% of double-chain alkyl dimethyl ammonium chloride, 0.1%-5% of iodine, 0.5%-10% of phosphoric acid and the balance of solvent. The invention provides a high-efficiency long-acting sterilizing agent which has the characteristics of high sterilization speed and high efficiency of an iodine sterilizing agent and the characteristics of long sterilization and bacterial inhibition duration of a quaternary ammonium salt sterilizing agent; through the mutual cooperation and synergistic effect of the double-chain alkyl dimethyl ammonium chloride and the iodine, the same sterilization effect can be achieved under the condition of low using amount, thus the utilization frequency can be reduced. A preparation method of the compound sterilizing agent is simple; the prepared product has the characteristics of good usability, good solubility, good stability, low using cost, safety, environmental protection and easy degradation and belongs to a non-toxic non-irrigating green environment-friendly product. The preparation method is simple in technological process, easy to control, short in production cycle, low in production cost and suitable for industrial production.
Description
Technical field
The invention belongs to disinfectant technical field, a kind of new green environment protection that particularly livestock breeding sterilization and fishery sterilization are used contains a kind of compound disinfecting bactericide of double-stranded alkyl-dimethyl ammonium chloride chelated iodine efficiently.
Background technology
Along with social fast development, people's living standard is in continuous improve, problem of environmental pollution affects people's life day by day, the factors such as haze, water pollution, light pollution, sandstorm cause environment increasingly serious, environmental protection more and more receives the government and society common people's concern, the idea of development of environmental protection conforms to the national strategy of sustainable development, is subject to social height accreditation and the active support of the government.
For pollutant is reached to sterilisation purpose, different classes of, different dosage form, the iodine sterile products of different efficacies is just being widely used in health, daily life, the aspects such as agriculture and animal husbandry aquaculture and drinking water, now widely used disinfectant is mainly iodine class, quaternary ammonium salt, and chloride class disinfectant, but in actual use, there is defect clearly in single disinfectant, as: quaternary ammonium disinfectant bactericidal effect is poor, working concentration is high, although good containing iodine and chlorine-containing disinfectant bactericidal effect, but the duration is short, frequency of utilization is high, these have all caused resource to be wasted greatly, excessively use also can cause certain influence to environment.
Summary of the invention
The object of the present invention is to provide a kind of environmental protection, cost low, technique is simple, the sterile products of good stability.
A kind of compound disinfecting bactericide, by double-stranded alkyl-dimethyl ammonium chloride, iodine, phosphoric acid, solvent composition, the percentage by weight of each component is:
Double-stranded alkyl-dimethyl ammonium chloride: 10%-75%; Iodine: 0.1%-5%; Phosphoric acid: 0.5%-10%; All the other are solvent.
Double-stranded alkyl-dimethyl ammonium chloride, iodine, phosphoric acid and solvent are added in reactor, be heated to 30 DEG C-90 DEG C, reaction 1-10 hour until iodine dissolves completely, obtains product after solution is cooling.
In technique scheme, described double-stranded alkyl-dimethyl ammonium chloride is at least made up of one of two decyl alkyl dimethyl ammonium chlorides, two octyldimethyl ammonium chlorides.
In above-mentioned preferred technical scheme, described double-stranded alkyl-dimethyl ammonium chloride is mixed and forms according to the ratio of 1:1-3 by two decyl alkyl dimethyl ammonium chlorides, two octyldimethyl ammonium chloride.
In technique scheme, described solvent adopts water or ethanol one.
The invention provides a kind of efficient long-acting disinfectant that can be widely used on livestock and poultry and fishery disinfection, both there is the high feature of the sterilization speed fast efficiency of sterilization degree of iodine class disinfectant, there is again long feature of quaternary ammonium disinfectant bactericidal duration, double-stranded alkyl-dimethyl ammonium chloride and iodine have collaborative and synergistic effect mutually, can be at the identical Disinfection Effect of being issued to of lower consumption, thereby can reach minimizing frequency of utilization, its preparation method is simple, the product usability of making is good, dissolubility is good, good stability, use cost is low, safety and environmental protection, the easily feature of degraded, belong to nontoxic non-irritating Green Product, technical process of the present invention is simple, easily control, with short production cycle, production cost is low, be applicable to suitability for industrialized production.
Embodiment
Below in conjunction with embodiments of the invention, technical scheme of the present invention is clearly and completely described, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiment.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtaining under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1: a kind of compound disinfecting bactericide, weight percentages of components is as follows:
Said components is added in reactor, be heated to 40 DEG C, react 6 hours, until iodine dissolves completely, after solution is cooling, obtain product.
Embodiment 2: a kind of compound disinfecting bactericide, weight percentages of components is as follows:
Said components is added in reactor, be heated to 40 DEG C, react 4 hours, until iodine dissolves completely, after solution is cooling, obtain product.
Embodiment 3: a kind of compound disinfecting bactericide, weight percentages of components is as follows:
Said components is added in reactor, be heated to 60 DEG C, react 4 hours, until iodine dissolves completely, after solution is cooling, obtain product.
Embodiment 4: a kind of compound disinfecting bactericide, weight percentages of components is as follows:
Said components is added in reactor, be heated to 60 DEG C, react 4 hours, until iodine dissolves completely, after solution is cooling, obtain product.
Embodiment 5: a kind of compound disinfecting bactericide, weight percentages of components is as follows:
Said components is added in reactor, be heated to 90 DEG C, react 2 hours, until iodine dissolves completely, after solution is cooling, obtain product.
To the various embodiments described above with the detection data of available iodine content, double-stranded alkyl-dimethyl ammonium chloride content in table 1.
Table 1 detects data
Table 1 illustrates that embodiment product available iodine content can reduce slightly with the resting period, but good stability.
Above-described embodiment 5 products obtained therefroms are carried out to sterilization experiment, Candida albicans, Escherichia coli, Staphylococcus aureus for the present invention, doing fungi, to kill experimental result as follows, in table 2, table 3, table 4.
One, equipment
(1) experimental strain Candida albicans, Escherichia coli, Staphylococcus aureus
(2) laboratory sample title: the last of the ten Heavenly stems Matsubain, povidone iodine, double-stranded alkyl-dimethyl ammonium chloride iodine.
(3) neutralizer: the PBS solution of the 0.03mol/L of 0.5%Na2S2O3+0.7% lecithin+2% Tween-80.
Two, method: test basis: " disinfection technology standard " (version in 2002) 2.1.1.9.5 fungi is killed experiment
Three, assay
Table 2, Candida albicans sterilization experiment result
According to above-mentioned experimental data, when sterilization logarithm value >4, the last of the ten Heavenly stems, Matsubain and povidone iodine were used separately least concentration for 1000mg/L effect 10 minutes and 50mg/L effect 10 minutes, if it is composite that double-stranded alkyl-dimethyl ammonium chloride and iodine are pressed 20:1, be 12.5mg/L at iodine concentration, double-stranded alkyl dimethyl ammonium chloride concentration is the sterilization logarithm value that 250mg/L effect can reach >4 for 10 minutes, so in sterilization experiment, the present invention has good sterilization and bacteriostasis effect to Candida albicans.
Table 3, Escherichia coli sterilization experiment result
According to above-mentioned experimental data, when sterilization logarithm value >4, the last of the ten Heavenly stems, Matsubain and povidone iodine were used separately least concentration for 1000mg/L effect 10 minutes and 50mg/L effect 10 minutes, if it is composite that double-stranded alkyl-dimethyl ammonium chloride and iodine are pressed 20:1, be 12.5mg/L at iodine concentration, double-stranded alkyl dimethyl ammonium chloride concentration is the sterilization logarithm value that 250mg/L effect can reach >4 for 10 minutes, so in sterilization experiment, the present invention has good sterilization and bacteriostasis effect to Candida albicans
Table 4, Staphylococcus aureus sterilization experiment result
According to above-mentioned experimental data, when sterilization logarithm value >4, the last of the ten Heavenly stems, Matsubain and povidone iodine were used separately least concentration for 1500mg/L effect 10 minutes and 75mg/L effect 10 minutes, if it is composite that double-stranded alkyl-dimethyl ammonium chloride and iodine are pressed 20:1, be 25mg/L at iodine concentration, double-stranded alkyl dimethyl ammonium chloride concentration is the sterilization logarithm value that 500mg/L effect can reach >4 for 10 minutes, so in sterilization experiment, the present invention has good sterilization and bacteriostasis effect to Staphylococcus aureus
Four, conclusion
According to above-mentioned experimental data, the bactericidal effect of a kind of compound disinfecting bactericide containing double-stranded alkyl-dimethyl ammonium chloride chelated iodine of the present invention be better than separately with povidone iodine or the last of the ten Heavenly stems Matsubain bactericidal effect, illustrate that double-stranded alkyl-dimethyl ammonium chloride chelated iodine is a kind of good spectrum sterilised products.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited to this, any be familiar with those skilled in the art the present invention disclose technical scope in; can expect easily changing or replacing, within all should being encompassed in protection scope of the present invention.Therefore, protection scope of the present invention should described be as the criterion with the protection domain of claim.
Claims (4)
1. a compound disinfecting bactericide, is characterized in that: by double-stranded alkyl-dimethyl ammonium chloride, iodine, phosphoric acid, solvent composition, the percentage by weight of each component is:
Double-stranded alkyl-dimethyl ammonium chloride: 10%-75%; Iodine: 0.1%-5%; Phosphoric acid: 0.5%-10%; All the other are solvent;
Double-stranded alkyl-dimethyl ammonium chloride, iodine, phosphoric acid and solvent are added in reactor, be heated to 30 DEG C-90 DEG C, reaction 1-10 hour until iodine dissolves completely, obtains product after solution is cooling.
2. a kind of compound disinfecting bactericide according to claim 1, is characterized in that: described double-stranded alkyl-dimethyl ammonium chloride is at least made up of one of two decyl alkyl dimethyl ammonium chlorides, two octyldimethyl ammonium chlorides.
3. a kind of compound disinfecting bactericide according to claim 2, is characterized in that: described double-stranded alkyl-dimethyl ammonium chloride is mixed and forms according to the ratio of 1:1-3 by two decyl alkyl dimethyl ammonium chlorides, two octyldimethyl ammonium chloride.
4. a kind of compound disinfecting bactericide according to claim 1, is characterized in that: described solvent adopts water or ethanol one.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410160247.XA CN103891772B (en) | 2014-04-21 | 2014-04-21 | A kind of compound disinfecting antibacterial |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410160247.XA CN103891772B (en) | 2014-04-21 | 2014-04-21 | A kind of compound disinfecting antibacterial |
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| CN103891772A true CN103891772A (en) | 2014-07-02 |
| CN103891772B CN103891772B (en) | 2016-07-20 |
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| CN201410160247.XA Active CN103891772B (en) | 2014-04-21 | 2014-04-21 | A kind of compound disinfecting antibacterial |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104604934A (en) * | 2015-01-21 | 2015-05-13 | 成都科宏达科技有限公司 | Novel composite iodine disinfectant as well as preparation method and application thereof |
| CN107619076A (en) * | 2017-11-08 | 2018-01-23 | 山东利水环保科技有限公司 | The formula of the special water purification agent of aquaculture class |
| CN108774144A (en) * | 2018-07-23 | 2018-11-09 | 山东利水环保科技有限公司 | Double ten alkyl methyls propyl ammonium iodides and its application |
| CN109042728A (en) * | 2018-09-19 | 2018-12-21 | 青岛安特斯生物制药有限公司 | A kind of iodine class disinfectant and its preparation and application |
| CN114532358A (en) * | 2021-12-01 | 2022-05-27 | 山东志存科技有限公司 | Synthesis process of mixed double-chain quaternary ammonium salt complex iodine for aquaculture |
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| CN1593150A (en) * | 2004-07-16 | 2005-03-16 | 哈尔滨工业大学 | Bi-dodecyl double quaternary ammonium salt iodine attached bactericide |
| CN1830250A (en) * | 2005-12-16 | 2006-09-13 | 李安民 | Biester quarternary ammoniumsalt compsite iodine bactericide |
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| CN1593150A (en) * | 2004-07-16 | 2005-03-16 | 哈尔滨工业大学 | Bi-dodecyl double quaternary ammonium salt iodine attached bactericide |
| CN1965651A (en) * | 2005-11-18 | 2007-05-23 | 天津市润拓生物技术有限公司 | Disinfectant containing clustered water for animal |
| CN1830250A (en) * | 2005-12-16 | 2006-09-13 | 李安民 | Biester quarternary ammoniumsalt compsite iodine bactericide |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104604934A (en) * | 2015-01-21 | 2015-05-13 | 成都科宏达科技有限公司 | Novel composite iodine disinfectant as well as preparation method and application thereof |
| CN104604934B (en) * | 2015-01-21 | 2017-11-03 | 成都科宏达科技有限公司 | A kind of compound iodine disinfectant and its preparation method and application |
| CN107619076A (en) * | 2017-11-08 | 2018-01-23 | 山东利水环保科技有限公司 | The formula of the special water purification agent of aquaculture class |
| CN107619076B (en) * | 2017-11-08 | 2020-08-14 | 山东利水环保科技有限公司 | Formula of special water purifying agent for aquaculture |
| CN108774144A (en) * | 2018-07-23 | 2018-11-09 | 山东利水环保科技有限公司 | Double ten alkyl methyls propyl ammonium iodides and its application |
| CN109042728A (en) * | 2018-09-19 | 2018-12-21 | 青岛安特斯生物制药有限公司 | A kind of iodine class disinfectant and its preparation and application |
| CN109042728B (en) * | 2018-09-19 | 2021-01-01 | 青岛安特斯生物制药有限公司 | Iodine disinfectant and preparation and use method thereof |
| CN114532358A (en) * | 2021-12-01 | 2022-05-27 | 山东志存科技有限公司 | Synthesis process of mixed double-chain quaternary ammonium salt complex iodine for aquaculture |
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| CN103891772B (en) | 2016-07-20 |
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Inventor after: Zhang Yuhong Inventor after: Lv Liang Inventor before: Zhang Yuhong Inventor before: Yao Yongyi |
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