CN103891772B - A kind of compound disinfecting antibacterial - Google Patents
A kind of compound disinfecting antibacterial Download PDFInfo
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- CN103891772B CN103891772B CN201410160247.XA CN201410160247A CN103891772B CN 103891772 B CN103891772 B CN 103891772B CN 201410160247 A CN201410160247 A CN 201410160247A CN 103891772 B CN103891772 B CN 103891772B
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- iodine
- double
- ammonium chloride
- alkyl dimethyl
- dimethyl ammonium
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Abstract
The invention provides a kind of compound disinfecting antibacterial, be made up of double-strand alkyl dimethyl ammonium chloride, iodine, phosphoric acid, solvent, the percentage by weight of each component is: double-strand alkyl dimethyl ammonium chloride: 10% 75%；Iodine: 0.1% 5%；Phosphoric acid: 0.5% 10%；Remaining is solvent, the invention provides the sterilization speed high feature of the fast efficiency of sterilization degree both with iodine class disinfectant, there is again the efficient long-acting disinfectant of quaternary ammonium disinfectant bactericidal persistent period long feature, double-strand alkyl dimethyl ammonium chloride and iodine have the most collaborative and potentiation, identical Disinfection Effect can be issued at lower consumption, frequency is used such that it is able to reach to reduce, its preparation method is simple, the product usability made is good, dissolubility is good, good stability, use cost is low, safety and environmental protection, degradable feature, belong to nontoxic non-irritating Green Product, present invention process process is simple, it is easily controlled, with short production cycle, production cost is low, it is suitable for industrialized production.
Description
Technical field
The invention belongs to disinfectant technical field, the one of use of sterilizing particularly to animal husbandry sterilization and fishery
New green environment protection contains a kind of compound disinfecting antibacterial of double-strand alkyl dimethyl ammonium chloride chelated iodine efficiently.
Background technology
Along with the fast development of society, the living standard of people is constantly improving, and problem of environmental pollution is day by day
Affecting the life of people, the factor such as the pollution of haze, water, light pollution, sandstorm causes environment increasingly serious,
Environmental protection is increasingly paid close attention to by government and the society common people, and the idea of development of environmental protection is sustainable with country
Development strategy is consistent, by highly recognition and the active support of the government of society.
In order to pollutant reach sterilisation purpose, iodine sterilization different classes of, different dosage form, different efficacies is produced
Product are just being widely used in the aspects such as health, daily life, agriculture and animal husbandry aquaculture and drinking water, are widely used at present
Disinfectant be mainly iodine class, quaternary ammonium salt, and chloride class disinfectant, but in actually used mistake
Cheng Zhong, there is defect clearly, such as: quaternary ammonium disinfectant bactericidal effect is poor, makes in single disinfectant
High by concentration, though good containing iodine and chlorine-containing disinfectant bactericidal effect, the persistent period is short, uses frequency high,
These have resulted in resource and have greatly wasted, and environment also can be caused certain impact by excessive use.
Summary of the invention
It is an object of the invention to provide a kind of environmental protection, low cost, technique is simple, the disappearing of good stability
Poison product.
A kind of compound disinfecting antibacterial, is made up of double-strand alkyl dimethyl ammonium chloride, iodine, phosphoric acid, solvent,
The percentage by weight of each component is:
Double-strand alkyl dimethyl ammonium chloride: 10%-75%；Iodine: 0.1%-5%；Phosphoric acid: 0.5%-10%；Remaining
For solvent.
Double-strand alkyl dimethyl ammonium chloride, iodine, phosphoric acid and solvent are added in reactor, is heated to 30 DEG C-90
DEG C, react 1-10 hour, until iodine is completely dissolved, after solution cools down, i.e. obtain product.
In technique scheme, described double-strand alkyl dimethyl ammonium chloride at least by double-track suspended self-propelled conveyor,
One of double octyldimethyl ammonium chloride form.
In above-mentioned preferred technical scheme, described double-strand alkyl dimethyl ammonium chloride is by double decyl dimethyl chlorinations
Ammonium, double octyldimethyl ammonium chloride mix composition according to the ratio of 1:1 3.
In technique scheme, described solvent uses water or ethanol a kind of.
The invention provides a kind of efficient long-acting can being widely used on poultry and fishery disinfection to disappear
Poisoning microbial inoculum, had both had the feature that the sterilization speed fast efficiency of sterilization degree of iodine class disinfectant is high, had had again quaternary ammonium salt
The feature of class disinfectant bactericidal persistent period length, double-strand alkyl dimethyl ammonium chloride and iodine have the most collaborative
And potentiation, identical Disinfection Effect can be issued at lower consumption, make such that it is able to reach minimizing
By frequency, its preparation method is simple, the product usability made is good, dissolubility is good, good stability, use
Low cost, safety and environmental protection, degradable feature, belong to nontoxic non-irritating Green Product, this
Bright technical process is simple, is easily controlled, and with short production cycle, production cost is low, is suitable for industrialized production.
Detailed description of the invention
Below in conjunction with embodiments of the invention, technical scheme is clearly and completely described,
Obviously, described embodiment is only a part of embodiment of the present invention rather than whole embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained under not making creative work premise
The every other embodiment obtained, broadly falls into the scope of protection of the invention.
Embodiment 1: a kind of compound disinfecting antibacterial, weight percentages of components is as follows:
Said components is added in reactor, be heated to 40 DEG C, react 6 hours, until iodine is completely dissolved,
Product is i.e. obtained after solution cools down.
Embodiment 2: a kind of compound disinfecting antibacterial, weight percentages of components is as follows:
Said components is added in reactor, be heated to 40 DEG C, react 4 hours, until iodine is completely dissolved,
Product is i.e. obtained after solution cools down.
Embodiment 3: a kind of compound disinfecting antibacterial, weight percentages of components is as follows:
Said components is added in reactor, be heated to 60 DEG C, react 4 hours, until iodine is completely dissolved,
Product is i.e. obtained after solution cools down.
Embodiment 4: a kind of compound disinfecting antibacterial, weight percentages of components is as follows:
Said components is added in reactor, be heated to 60 DEG C, react 4 hours, until iodine is completely dissolved,
Product is i.e. obtained after solution cools down.
Embodiment 5: a kind of compound disinfecting antibacterial, weight percentages of components is as follows:
Said components is added in reactor, be heated to 90 DEG C, react 2 hours, until iodine is completely dissolved,
Product is i.e. obtained after solution cools down.
The various embodiments described above are shown in the detection data of available iodine content, double-strand alkyl dimethyl ammonium chloride content
Table 1.
Table 1 detects data
Table 1 illustrates that embodiment product available iodine content can slightly reduce with the resting period, but good stability.
Above-described embodiment 5 products obtained therefrom is carried out sterilization experiment, present invention Candida albicans, escherichia coli,
Staphylococcus aureus, is cooked fungus killing test result as follows, is shown in Table 2, table 3, table 4.
One, equipment
(1) experimental strain Candida albicans, escherichia coli, staphylococcus aureus
(2) laboratory sample title: the last of the ten Heavenly stems Matsubain, povidone iodine, double-strand alkyl dimethyl ammonium chloride iodine.
(3) nertralizer: the PBS of the 0.03mol/L of 0.5%Na2S2O3+0.7% lecithin+2% tween 80
Solution.
Two, method: test basis: " disinfection technology standard " (version in 2002) 2.1.1.9.5 fungus kills
Go out experiment
Three, assay
Table 2, Candida albicans sterilization experiment result
According to above-mentioned experimental data, sterilize logarithm value > 4 time, the last of the ten Heavenly stems Matsubain and povidone iodine be used alone minimum
Concentration is 1000mg/L effect 10 minutes and 50mg/L effect 10 minutes, if double-strand alkyl dimethyl chlorine
Changing ammonium and iodine is pressed 20:1 and compounded, be 12.5mg/L at iodine concentration, double-strand alkyl dimethyl ammonium chloride concentration is
250mg/L effect i.e. can reach for 10 minutes > the sterilization logarithm value of 4, so in sterilization experiment, the present invention couple
Candida albicans has good sterilization and bacteriostasis effect.
Table 3, escherichia coli sterilization experiment result
According to above-mentioned experimental data, sterilize logarithm value > 4 time, the last of the ten Heavenly stems Matsubain and povidone iodine be used alone minimum
Concentration is 1000mg/L effect 10 minutes and 50mg/L effect 10 minutes, if double-strand alkyl dimethyl chlorine
Changing ammonium and iodine is pressed 20:1 and compounded, be 12.5mg/L at iodine concentration, double-strand alkyl dimethyl ammonium chloride concentration is
250mg/L effect i.e. can reach for 10 minutes > the sterilization logarithm value of 4, so in sterilization experiment, the present invention couple
Candida albicans has good sterilization and bacteriostasis effect,
Table 4, staphylococcus aureus sterilization experiment result
According to above-mentioned experimental data, sterilize logarithm value > 4 time, the last of the ten Heavenly stems Matsubain and povidone iodine be used alone minimum
Concentration is 1500mg/L effect 10 minutes and 75mg/L effect 10 minutes, if double-strand alkyl dimethyl chlorine
Changing ammonium and iodine is pressed 20:1 and compounded, be 25mg/L at iodine concentration, double-strand alkyl dimethyl ammonium chloride concentration is
500mg/L effect i.e. can reach for 10 minutes > the sterilization logarithm value of 4, so in sterilization experiment, the present invention couple
Staphylococcus aureus has good sterilization and bacteriostasis effect,
Four, conclusion
According to above-mentioned experimental data, a kind of compound recipe containing double-strand alkyl dimethyl ammonium chloride chelated iodine of the present invention
The bactericidal effect of disinfectant is better than independent povidone iodine or the bactericidal effect of Matsubain in the last of the ten Heavenly stems, illustrates double
Alkyl group alkyl dimethyl ammonium chloride chelated iodine is a kind of excellent spectrum sterilised products.
The above, the only detailed description of the invention of the present invention, but protection scope of the present invention is not limited to
This, any those familiar with the art, in the technical scope that the invention discloses, can readily occur in
Change or replacement, all should contain within protection scope of the present invention.Therefore, protection scope of the present invention should
Described it is as the criterion with scope of the claims.
Claims (1)
1. a compound disinfecting antibacterial, it is characterised in that: by double-strand alkyl dimethyl ammonium chloride, iodine,
Phosphoric acid, solvent form, and the percentage by weight of each component is:
Double-strand alkyl dimethyl ammonium chloride: 60%；Iodine: 3.5%；Phosphoric acid: 5%；Remaining is solvent；Described
Solvent uses ethanol；
Described double-strand alkyl dimethyl ammonium chloride is by double octyldimethyl ammonium chloride, double-track suspended self-propelled conveyor
Composition is mixed according to the ratio of 1:3；
Double-strand alkyl dimethyl ammonium chloride, iodine, phosphoric acid and solvent are added in reactor, are heated to 90 DEG C,
React 1-10 hour, until iodine is completely dissolved, after solution cools down, i.e. obtain product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201410160247.XA CN103891772B (en) | 2014-04-21 | 2014-04-21 | A kind of compound disinfecting antibacterial |
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| CN201410160247.XA CN103891772B (en) | 2014-04-21 | 2014-04-21 | A kind of compound disinfecting antibacterial |
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| CN103891772A CN103891772A (en) | 2014-07-02 |
| CN103891772B true CN103891772B (en) | 2016-07-20 |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104604934B (en) * | 2015-01-21 | 2017-11-03 | 成都科宏达科技有限公司 | A kind of compound iodine disinfectant and its preparation method and application |
| CN107619076B (en) * | 2017-11-08 | 2020-08-14 | 山东利水环保科技有限公司 | Formula of special water purifying agent for aquaculture |
| CN108774144A (en) * | 2018-07-23 | 2018-11-09 | 山东利水环保科技有限公司 | Double ten alkyl methyls propyl ammonium iodides and its application |
| CN109042728B (en) * | 2018-09-19 | 2021-01-01 | 青岛安特斯生物制药有限公司 | Iodine disinfectant and preparation and use method thereof |
| CN114532358A (en) * | 2021-12-01 | 2022-05-27 | 山东志存科技有限公司 | Synthesis process of mixed double-chain quaternary ammonium salt complex iodine for aquaculture |
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|---|---|---|---|---|
| CN1593150A (en) * | 2004-07-16 | 2005-03-16 | 哈尔滨工业大学 | Bi-dodecyl double quaternary ammonium salt iodine attached bactericide |
| CN1830250A (en) * | 2005-12-16 | 2006-09-13 | 李安民 | Biester quarternary ammoniumsalt compsite iodine bactericide |
| CN1965651A (en) * | 2005-11-18 | 2007-05-23 | 天津市润拓生物技术有限公司 | Disinfectant containing clustered water for animal |
| CN102550602A (en) * | 2010-11-30 | 2012-07-11 | 中国科学院成都有机化学有限公司 | High-iodine controlled-release type sanitizer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH703973A1 (en) * | 2010-10-29 | 2012-04-30 | Obrist Engineering Gmbh | Temperature-controlled battery. |
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2014
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1593150A (en) * | 2004-07-16 | 2005-03-16 | 哈尔滨工业大学 | Bi-dodecyl double quaternary ammonium salt iodine attached bactericide |
| CN1965651A (en) * | 2005-11-18 | 2007-05-23 | 天津市润拓生物技术有限公司 | Disinfectant containing clustered water for animal |
| CN1830250A (en) * | 2005-12-16 | 2006-09-13 | 李安民 | Biester quarternary ammoniumsalt compsite iodine bactericide |
| CN102550602A (en) * | 2010-11-30 | 2012-07-11 | 中国科学院成都有机化学有限公司 | High-iodine controlled-release type sanitizer |
Non-Patent Citations (2)
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| 双季铵盐络合碘;无;《无》;20121029;全文 * |
| 碘制剂在水产上的应用;王民权 等;《渔业现代化》;20051231(第2期);第26-27页 * |
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Inventor after: Zhang Yuhong Inventor after: Lv Liang Inventor before: Zhang Yuhong Inventor before: Yao Yongyi |
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