CN115087631B - FormII型的还原型辅酶Q10结晶的制造方法 - Google Patents

FormII型的还原型辅酶Q10结晶的制造方法 Download PDF

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Publication number
CN115087631B
CN115087631B CN202180014205.3A CN202180014205A CN115087631B CN 115087631 B CN115087631 B CN 115087631B CN 202180014205 A CN202180014205 A CN 202180014205A CN 115087631 B CN115087631 B CN 115087631B
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crystals
reduced coenzyme
formii
temperature
type
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Chinese (zh)
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CN115087631A (zh
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北村志郎
木下浩一
植田尚宏
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Kaneka Corp
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Kaneka Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/34—Separation; Purification; Stabilisation; Use of additives
    • C07C41/40—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN202180014205.3A 2020-02-12 2021-01-29 FormII型的还原型辅酶Q10结晶的制造方法 Active CN115087631B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020-021358 2020-02-12
JP2020021358 2020-02-12
PCT/JP2021/003220 WO2021161807A1 (ja) 2020-02-12 2021-01-29 ＦｏｒｍＩＩ型の還元型補酵素Ｑ１０結晶の製造方法

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CN115087631A CN115087631A (zh) 2022-09-20
CN115087631B true CN115087631B (zh) 2024-05-14

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US (1) US20230339836A1 (https=)
EP (1) EP4105194A4 (https=)
JP (2) JPWO2021161807A1 (https=)
CN (1) CN115087631B (https=)
WO (1) WO2021161807A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022202213A1 (ja) * 2021-03-26 2022-09-29 株式会社カネカ ＦｏｒｍＩＩ型の還元型補酵素Ｑ１０結晶又はその結晶性固体の製造方法
WO2022202214A1 (ja) * 2021-03-26 2022-09-29 株式会社カネカ ＦｏｒｍＩＩ型の還元型補酵素Ｑ１０結晶又はその結晶性固体の製造方法
EP4317125B1 (en) * 2021-03-26 2026-04-29 Kaneka Corporation Method for producing form-ii type reduced coenzyme q10 crystal or crystalline solid of same, and crystallizing apparatus
JPWO2023120553A1 (https=) * 2021-12-24 2023-06-29
JPWO2023120557A1 (https=) * 2021-12-24 2023-06-29
JPWO2024204380A1 (https=) * 2023-03-30 2024-10-03

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012176842A1 (ja) * 2011-06-24 2012-12-27 株式会社カネカ 安定性に優れた還元型補酵素ｑ１０結晶

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3889481B2 (ja) 1996-08-16 2007-03-07 株式会社カネカ 医薬組成物
TWI237018B (en) 2001-07-13 2005-08-01 Kaneka Corp Method of producing reduced coenzyme Q10 crystals
TWI310029B (https=) * 2001-07-13 2009-05-21 Kaneka Corp
JP4170657B2 (ja) 2001-07-13 2008-10-22 株式会社カネカ 還元型補酵素ｑ１０の結晶化法
WO2009057611A1 (ja) * 2007-10-30 2009-05-07 Kaneka Corporation 含水有機溶媒を用いる還元型補酵素ｑ１０の製造方法
JP6704433B2 (ja) 2018-08-02 2020-06-03 三菱電機インフォメーションシステムズ株式会社 入退室管理サーバおよび入退室管理システム
JP7330987B2 (ja) * 2018-08-30 2023-08-22 株式会社カネカ 安定性に優れた還元型補酵素ｑ１０結晶の製造方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012176842A1 (ja) * 2011-06-24 2012-12-27 株式会社カネカ 安定性に優れた還元型補酵素ｑ１０結晶
CN103635452A (zh) * 2011-06-24 2014-03-12 株式会社钟化 稳定性优良的还原型辅酶q10晶体

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Publication number Publication date
CN115087631A (zh) 2022-09-20
US20230339836A1 (en) 2023-10-26
EP4105194A4 (en) 2024-03-13
JPWO2021161807A1 (https=) 2021-08-19
EP4105194A1 (en) 2022-12-21
WO2021161807A1 (ja) 2021-08-19
JP2025109930A (ja) 2025-07-25

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