CN1142923C - 12,13-修饰的依泊斯隆衍生物 - Google Patents

12,13-修饰的依泊斯隆衍生物 Download PDF

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Publication number
CN1142923C
CN1142923C CNB998052663A CN99805266A CN1142923C CN 1142923 C CN1142923 C CN 1142923C CN B998052663 A CNB998052663 A CN B998052663A CN 99805266 A CN99805266 A CN 99805266A CN 1142923 C CN1142923 C CN 1142923C
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China
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methyl
alkyl
compound
thiazolyl
substituted
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Expired - Fee Related
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CNB998052663A
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English (en)
Chinese (zh)
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CN1298398A (zh
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G��D����
G·D·维特
K
S·－H·K·金
G·霍夫勒
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CNB998052663A 1998-04-21 1999-04-05 12,13-修饰的依泊斯隆衍生物 Expired - Fee Related CN1142923C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8256498P 1998-04-21 1998-04-21
US60/082564 1998-04-21

Publications (2)

Publication Number Publication Date
CN1298398A CN1298398A (zh) 2001-06-06
CN1142923C true CN1142923C (zh) 2004-03-24

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Family Applications (1)

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CNB998052663A Expired - Fee Related CN1142923C (zh) 1998-04-21 1999-04-05 12,13-修饰的依泊斯隆衍生物

Country Status (17)

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US (2) US6380395B1 (enExample)
EP (3) EP1073647B1 (enExample)
JP (2) JP4476483B2 (enExample)
CN (1) CN1142923C (enExample)
AR (2) AR015007A1 (enExample)
AT (2) ATE340177T1 (enExample)
AU (2) AU748526B2 (enExample)
BR (1) BR9909795A (enExample)
CA (2) CA2329181C (enExample)
CY (2) CY1105836T1 (enExample)
DE (2) DE69933287T2 (enExample)
DK (3) DK1073648T3 (enExample)
ES (3) ES2400049T3 (enExample)
PE (1) PE20000460A1 (enExample)
PT (3) PT1073648E (enExample)
TR (1) TR200003036T2 (enExample)
WO (2) WO1999054319A1 (enExample)

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WO2003026744A1 (en) * 2001-09-25 2003-04-03 Alcon, Inc. The use of epothilones and analogs in conjunction with ophthalmic surgery
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Also Published As

Publication number Publication date
EP1589017A2 (en) 2005-10-26
DE69933287D1 (de) 2006-11-02
PE20000460A1 (es) 2000-06-09
AU3382799A (en) 1999-11-08
DK1073647T3 (da) 2009-11-09
CY1105836T1 (el) 2011-02-02
WO1999054318A1 (en) 1999-10-28
DK1073648T3 (da) 2007-01-08
JP2002512238A (ja) 2002-04-23
ES2273484T3 (es) 2007-05-01
PT1073647E (pt) 2009-07-17
EP1073648A1 (en) 2001-02-07
CY1109593T1 (el) 2014-08-13
AU757733B2 (en) 2003-03-06
EP1589017A3 (en) 2009-04-22
CA2329181C (en) 2011-02-22
US6380395B1 (en) 2002-04-30
ES2327803T3 (es) 2009-11-03
JP4476483B2 (ja) 2010-06-09
AR015007A1 (es) 2001-04-11
CA2329181A1 (en) 1999-10-28
PT1073648E (pt) 2006-12-29
PT1589017E (pt) 2013-03-04
EP1073648B1 (en) 2006-09-20
EP1073647A4 (en) 2003-01-02
EP1073647B1 (en) 2009-07-08
AU748526B2 (en) 2002-06-06
BR9909795A (pt) 2000-12-26
ATE435861T1 (de) 2009-07-15
CA2323609A1 (en) 1999-10-28
TR200003036T2 (tr) 2001-01-22
DE69933287T2 (de) 2007-05-03
ATE340177T1 (de) 2006-10-15
WO1999054319A1 (en) 1999-10-28
DE69941083D1 (en) 2009-08-20
US6399638B1 (en) 2002-06-04
ES2400049T3 (es) 2013-04-05
CN1298398A (zh) 2001-06-06
JP2002512239A (ja) 2002-04-23
EP1073648A4 (en) 2003-01-02
AU3471699A (en) 1999-11-08
EP1589017B1 (en) 2012-12-05
EP1073647A1 (en) 2001-02-07
DK1589017T3 (da) 2013-03-18
AR015774A1 (es) 2001-05-16

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