IL156578A0 - A method for formulating an epothilone analog for pharmaceutical use and pharmaceutical preparations including an epothilone analog - Google Patents

A method for formulating an epothilone analog for pharmaceutical use and pharmaceutical preparations including an epothilone analog

Info

Publication number
IL156578A0
IL156578A0 IL15657802A IL15657802A IL156578A0 IL 156578 A0 IL156578 A0 IL 156578A0 IL 15657802 A IL15657802 A IL 15657802A IL 15657802 A IL15657802 A IL 15657802A IL 156578 A0 IL156578 A0 IL 156578A0
Authority
IL
Israel
Prior art keywords
epothilone analog
formulating
pharmaceutical
preparations including
pharmaceutical preparations
Prior art date
Application number
IL15657802A
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of IL156578A0 publication Critical patent/IL156578A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IL15657802A 2001-01-25 2002-01-22 A method for formulating an epothilone analog for pharmaceutical use and pharmaceutical preparations including an epothilone analog IL156578A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26422801P 2001-01-25 2001-01-25
US29000601P 2001-05-11 2001-05-11
PCT/US2002/001813 WO2002058700A1 (en) 2001-01-25 2002-01-22 Methods of administering epothilone analogs for the treatment of cancer

Publications (1)

Publication Number Publication Date
IL156578A0 true IL156578A0 (en) 2004-01-04

Family

ID=26950348

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15657802A IL156578A0 (en) 2001-01-25 2002-01-22 A method for formulating an epothilone analog for pharmaceutical use and pharmaceutical preparations including an epothilone analog

Country Status (10)

Country Link
JP (1) JP4633331B2 (en)
AU (1) AU2002245296B2 (en)
CA (1) CA2434526C (en)
HR (1) HRP20030677B1 (en)
IL (1) IL156578A0 (en)
MX (1) MXPA03006412A (en)
NO (1) NO335119B1 (en)
PL (1) PL207720B1 (en)
RU (1) RU2292202C2 (en)
WO (1) WO2002058700A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6867305B2 (en) 1996-12-03 2005-03-15 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
WO1999001124A1 (en) 1996-12-03 1999-01-14 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US8618085B2 (en) * 2000-04-28 2013-12-31 Koasn Biosciences Incorporated Therapeutic formulations of desoxyepothilones
NZ526871A (en) 2001-01-25 2006-01-27 Bristol Myers Squibb Co Pharmaceutical dosage forms of epothilones for oral administration
GB0305928D0 (en) * 2003-03-14 2003-04-23 Novartis Ag Organic compounds
AU2008200555C1 (en) * 2003-03-14 2011-12-15 Novartis Ag Treatment of proliferative diseases with epothilone derivatives and radiation
EP1674098A1 (en) * 2004-12-23 2006-06-28 Schering Aktiengesellschaft Stable and tolerable parental formulations of highly reactive organic drug substances with low or no solubility in water
ES2881391T3 (en) * 2007-06-01 2021-11-29 Wyeth Llc Treatment of imatinib-resistant chronic myelogenous leukemia having the 1457T> C mutation in the BcrAbl gene using the compound bosutinib
WO2009089138A1 (en) * 2008-01-04 2009-07-16 Bristol-Myers Squibb Company Oral administration of ixabepilone

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW406020B (en) * 1993-09-29 2000-09-21 Bristol Myers Squibb Co Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
US5681846A (en) * 1995-03-17 1997-10-28 Board Of Regents, The University Of Texas System Extended stability formulations for paclitaxel
WO1999001124A1 (en) * 1996-12-03 1999-01-14 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US6605599B1 (en) * 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
WO1999004330A1 (en) * 1997-07-18 1999-01-28 Hewlett-Packard Company Format for passing information between devices
US6365749B1 (en) * 1997-12-04 2002-04-02 Bristol-Myers Squibb Company Process for the preparation of ring-opened epothilone intermediates which are useful for the preparation of epothilone analogs
AR017979A1 (en) * 1998-02-05 2001-10-24 Novartis Ag PHARMACEUTICAL FORMULATIONS OF EPOTILONES, METHOD FOR THE PREPARATION AND USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT
FR2775187B1 (en) * 1998-02-25 2003-02-21 Novartis Ag USE OF EPOTHILONE B FOR THE MANUFACTURE OF AN ANTIPROLIFERATIVE PHARMACEUTICAL PREPARATION AND A COMPOSITION COMPRISING EPOTHILONE B AS AN IN VIVO ANTIPROLIFERATIVE AGENT
US6380395B1 (en) * 1998-04-21 2002-04-30 Bristol-Myers Squibb Company 12, 13-cyclopropane epothilone derivatives
EA009206B1 (en) * 1999-02-18 2007-12-28 Шеринг Акциенгезельшафт 16-halogen-epothilone derivatives and their pharmaceutical use
UA75365C2 (en) * 2000-08-16 2006-04-17 Bristol Myers Squibb Co Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon

Also Published As

Publication number Publication date
PL373727A1 (en) 2005-09-05
AU2002245296B2 (en) 2006-12-21
NO20033341L (en) 2003-09-04
WO2002058700A1 (en) 2002-08-01
HRP20030677B1 (en) 2011-10-31
RU2292202C2 (en) 2007-01-27
RU2003126170A (en) 2005-02-27
JP4633331B2 (en) 2011-02-16
JP2005503323A (en) 2005-02-03
HRP20030677A2 (en) 2004-08-31
CA2434526A1 (en) 2002-08-01
NO20033341D0 (en) 2003-07-24
PL207720B1 (en) 2011-01-31
CA2434526C (en) 2011-11-01
NO335119B1 (en) 2014-09-22
MXPA03006412A (en) 2003-10-15

Similar Documents

Publication Publication Date Title
IL156580A0 (en) A method for formulating an epothilone analog for parenteral use and pharmaceutical preparations including an epothilone analog
EP1391212A4 (en) Oral preparations and supports for oral preparations
EP1367060A4 (en) Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
EP1364957A4 (en) Glycopyranosyloxypyrazole derivatives and medicinal use thereof
EP1364958A4 (en) Glycopyranosyloxypyrazole derivatives and medicinal use thereof
EP1248369A3 (en) Proximity sensor and a method for operating same
AU2001280188A1 (en) Pyrazolopyridine compound and pharmaceutical use thereof
AU4694501A (en) Protein capable of self-assembly at a hydrophobic-hydrophilic interface and usesthereof
AU2002362129A1 (en) A universal electrocardiogram sensor positioning device and method for four sizes including extra large
AU2001262221A1 (en) Novel epothilone derivatives, method for the preparation thereof and their pharmaceutical use
AU2002354476A1 (en) Pyrazolopyridine derivatives and medicinal use thereof
AU2002339080A1 (en) Apparatus and method for registering the position of a surgical robot
IL156578A0 (en) A method for formulating an epothilone analog for pharmaceutical use and pharmaceutical preparations including an epothilone analog
PL360885A1 (en) 10-aryl-11h-benzo [b]fluorene derivatives and analogs for medicinal use
PT1377578E (en) Beta-carboline derivatives and its pharmaceutical use against depression and anxiety
AU2002360477A1 (en) A dental impression method and device
HUP0401153A3 (en) Combinations comprising epothilones and pharmaceutical uses thereof
SI1581258T1 (en) Pharmaceutical formulation and a method of making same
AU2001256953A1 (en) Method and apparatus for biopotential sensing and stimulation
AU2002340328A1 (en) Olanzapine dihydrate-ii a process for its preparation and use thereof
AU2992901A (en) Method for preparing and administering medicinal plant material
AUPR916301A0 (en) Pyrazolopyridine compound and pharmaceutical use thereof
AUPR606401A0 (en) Pyrazolopyridine compound and pharmaceutical use thereof
AU2002211147A1 (en) Apparatus for making dental inlays and the like
AUPR548601A0 (en) Pyrazolopyrazinecompound and pharmaceutical use thereof

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees