CN113679698B - 包含半氟化烷烃的混合物的组合物 - Google Patents

包含半氟化烷烃的混合物的组合物 Download PDF

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Publication number
CN113679698B
CN113679698B CN202110962896.1A CN202110962896A CN113679698B CN 113679698 B CN113679698 B CN 113679698B CN 202110962896 A CN202110962896 A CN 202110962896A CN 113679698 B CN113679698 B CN 113679698B
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compositions
composition
eye
semifluorinated
keratoconjunctivitis sicca
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Chinese (zh)
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CN113679698A (zh
Inventor
伯恩哈德·金特
巴斯蒂安·泰辛格
索尼娅·泰辛格
迪特尔·谢勒
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Novaliq GmbH
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Novaliq GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN202110962896.1A 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物 Active CN113679698B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12183997.1 2012-09-12
EP12183997 2012-09-12
CN201380044597.3A CN104619314B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
PCT/EP2013/068882 WO2014041055A1 (en) 2012-09-12 2013-09-12 Compositions comprising mixtures of semifluorinated alkanes

Related Parent Applications (1)

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CN201380044597.3A Division CN104619314B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物

Publications (2)

Publication Number Publication Date
CN113679698A CN113679698A (zh) 2021-11-23
CN113679698B true CN113679698B (zh) 2022-07-26

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Family Applications (7)

Application Number Title Priority Date Filing Date
CN202110962896.1A Active CN113679698B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN201380044597.3A Active CN104619314B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN202110965002.4A Active CN113679699B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN202111229399.7A Active CN113952321B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN202110961096.8A Active CN113694048B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN201610727043.9A Active CN106511322B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN202110962784.6A Pending CN113679697A (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物

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CN201380044597.3A Active CN104619314B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN202110965002.4A Active CN113679699B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN202111229399.7A Active CN113952321B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN202110961096.8A Active CN113694048B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN201610727043.9A Active CN106511322B (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物
CN202110962784.6A Pending CN113679697A (zh) 2012-09-12 2013-09-12 包含半氟化烷烃的混合物的组合物

Country Status (13)

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US (4) US10449164B2 (enExample)
EP (2) EP3100722B1 (enExample)
JP (3) JP6352266B2 (enExample)
KR (2) KR102158400B1 (enExample)
CN (7) CN113679698B (enExample)
AU (3) AU2013314370B2 (enExample)
BR (1) BR112015004997B1 (enExample)
CA (2) CA2883002C (enExample)
DE (1) DE202013012742U1 (enExample)
ES (2) ES2770398T3 (enExample)
MX (2) MX360469B (enExample)
MY (1) MY166228A (enExample)
WO (1) WO2014041055A1 (enExample)

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JP6039145B2 (ja) 2011-05-25 2016-12-07 ノバリック ゲーエムベーハー 半フッ化アルカンを基礎にした局所薬学的組成物
JP6023181B2 (ja) 2011-05-25 2016-11-09 ノバリック ゲーエムベーハー 爪に投与するための医薬組成物
CN104066442B (zh) 2012-01-23 2018-05-18 诺瓦利克有限责任公司 基于半氟化烷烃的稳定蛋白质组合物
MX360469B (es) 2012-09-12 2018-11-05 Novaliq Gmbh Composiciones que comprenden mezclas de alcanos semifluorados.
DE202013012753U1 (de) 2012-09-12 2019-03-04 Novaliq Gmbh Zusammensetzungen semifluorierter Alkane zur Verwendung in der Behandlung von Keratoconjunctivitis Sicca
WO2015011199A1 (en) 2013-07-23 2015-01-29 Novaliq Gmbh Stabilized antibody compositions
CN120884568A (zh) 2015-09-30 2025-11-04 诺瓦利克有限责任公司 半氟化化合物和其组合物
ES2953837T3 (es) * 2015-09-30 2023-11-16 Novaliq Gmbh 2-perfluorobutil pentano para administración oftálmica
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US10098895B2 (en) * 2016-09-07 2018-10-16 Glia, Llc Treatment of symptoms related to neurodegenerative disorders through pharmacological dermal activation of cranial nerves
US11684589B2 (en) 2016-09-22 2023-06-27 Novaliq Gmbh Pharmaceutical compositions for use in the therapy of blepharitis
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EP3698785A1 (en) * 2016-09-28 2020-08-26 Novaliq GmbH Compositions comprising a cannabinoid receptor binding ligand
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KR101895321B1 (ko) 2017-04-24 2018-09-05 주식회사 이루다 눈꺼풀의 분비샘 이상에 대한 치료장치
US10717691B2 (en) 2017-05-05 2020-07-21 Novaliq Gmbh Process for the production of semifluorinated alkanes
US20210069014A1 (en) 2017-05-06 2021-03-11 Novaliq Gmbh Drop dispenser
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IL273531B2 (en) 2017-09-27 2024-05-01 Novaliq Gmbh Ophthalmic compositions comprising latanoprost for use in the treatment of ocular diseases
US11896559B2 (en) 2017-10-04 2024-02-13 Novaliq Gmbh Opthalmic compositions comprising F6H8
EP3758676A1 (en) 2018-03-02 2021-01-06 Novaliq GmbH Pharmaceutical compositions comprising nebivolol
JP2021522219A (ja) 2018-04-27 2021-08-30 ノバリック ゲーエムベーハー 緑内障の治療のためのタフルプロストを含む眼科用組成物
KR20210080388A (ko) 2018-09-22 2021-06-30 노바리크 게엠베하 안구 표면 손상 및 건조 증상 치료를 위한 안약 조성물
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WO2020074697A1 (en) 2018-10-12 2020-04-16 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
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