CN1133431C - 用罗西格列酮和胰岛素治疗糖尿病 - Google Patents

用罗西格列酮和胰岛素治疗糖尿病 Download PDF

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Publication number
CN1133431C
CN1133431C CNB988062232A CN98806223A CN1133431C CN 1133431 C CN1133431 C CN 1133431C CN B988062232 A CNB988062232 A CN B988062232A CN 98806223 A CN98806223 A CN 98806223A CN 1133431 C CN1133431 C CN 1133431C
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CN
China
Prior art keywords
chemical compound
pharmaceutically acceptable
insulin
diabetes
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB988062232A
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English (en)
Chinese (zh)
Other versions
CN1260715A (zh
Inventor
��S��A��ʷ����˹
S·A·史密斯
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SmithKline Beecham Ltd
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SmithKline Beecham Ltd
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Publication of CN1260715A publication Critical patent/CN1260715A/zh
Application granted granted Critical
Publication of CN1133431C publication Critical patent/CN1133431C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
CNB988062232A 1997-06-18 1998-06-15 用罗西格列酮和胰岛素治疗糖尿病 Expired - Fee Related CN1133431C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9712866.4 1997-06-18
GBGB9712866.4A GB9712866D0 (en) 1997-06-18 1997-06-18 Novel method of treatment

Publications (2)

Publication Number Publication Date
CN1260715A CN1260715A (zh) 2000-07-19
CN1133431C true CN1133431C (zh) 2004-01-07

Family

ID=10814527

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988062232A Expired - Fee Related CN1133431C (zh) 1997-06-18 1998-06-15 用罗西格列酮和胰岛素治疗糖尿病

Country Status (30)

Country Link
EP (1) EP0999837A1 (enrdf_load_stackoverflow)
JP (1) JP2002504138A (enrdf_load_stackoverflow)
KR (1) KR20010013843A (enrdf_load_stackoverflow)
CN (1) CN1133431C (enrdf_load_stackoverflow)
AP (1) AP1287A (enrdf_load_stackoverflow)
AR (2) AR015894A1 (enrdf_load_stackoverflow)
AU (1) AU8216398A (enrdf_load_stackoverflow)
BG (1) BG104059A (enrdf_load_stackoverflow)
BR (1) BR9810444A (enrdf_load_stackoverflow)
CA (1) CA2294141A1 (enrdf_load_stackoverflow)
CO (1) CO4940454A1 (enrdf_load_stackoverflow)
DZ (1) DZ2521A1 (enrdf_load_stackoverflow)
EA (1) EA004800B1 (enrdf_load_stackoverflow)
GB (1) GB9712866D0 (enrdf_load_stackoverflow)
HU (1) HUP0003260A3 (enrdf_load_stackoverflow)
ID (1) ID23951A (enrdf_load_stackoverflow)
IL (1) IL133143A0 (enrdf_load_stackoverflow)
IN (1) IN189723B (enrdf_load_stackoverflow)
MA (1) MA26511A1 (enrdf_load_stackoverflow)
NO (1) NO996265D0 (enrdf_load_stackoverflow)
OA (1) OA11517A (enrdf_load_stackoverflow)
PE (1) PE104499A1 (enrdf_load_stackoverflow)
PL (1) PL343123A1 (enrdf_load_stackoverflow)
SK (1) SK179399A3 (enrdf_load_stackoverflow)
TR (1) TR199903095T2 (enrdf_load_stackoverflow)
TW (1) TW587937B (enrdf_load_stackoverflow)
UA (1) UA70299C2 (enrdf_load_stackoverflow)
UY (1) UY25050A1 (enrdf_load_stackoverflow)
WO (1) WO1998057636A1 (enrdf_load_stackoverflow)
ZA (1) ZA985237B (enrdf_load_stackoverflow)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291495B1 (en) * 1997-02-24 2001-09-18 Robert B. Rieveley Method and composition for the treatment of diabetes
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
TWI249401B (en) 1999-04-14 2006-02-21 Takeda Chemical Industries Ltd Agent for improving ketosis
PT1173434E (pt) 1999-04-23 2003-12-31 Smithkline Beecham Plc Novo produto farmaceutico
SI1133312T1 (sl) * 1999-06-21 2008-02-29 Lilly Co Eli Uporaba tiazolidindionov v kombinaciji z glukagonu podobnim peptidom-1 in njegovimi agonisti za zdravljenje sladkorne bolezni, neodvisne od inzulina
AU5760900A (en) * 1999-06-25 2001-01-31 Minimed, Inc. Multiple agent diabetes therapy
US6468507B1 (en) * 2000-05-01 2002-10-22 Aeropharm Technology, Inc. Non-aqueous aerosol formulation comprising rosiglitazone maleate, a non-aqueous carrier, and an amino acid stabilizer
GB0023970D0 (en) * 2000-09-29 2000-11-15 Smithkline Beecham Plc Novel pharmaceutical
AU2002248464A1 (en) 2001-02-21 2002-09-12 Medtronic Minimed, Inc. Stabilized insulin formulations
US6531461B1 (en) 2001-06-04 2003-03-11 Louis Obyo Obyo Nelson Medicament for the treatment of diabetes
WO2002100396A1 (en) * 2001-06-07 2002-12-19 Wyeth COMBINATION OF A PTPase INHIBITOR AND A THIAZOLIDINEDIONE AGENT
US6737401B2 (en) 2001-06-28 2004-05-18 Metronic Minimed, Inc. Methods of evaluating protein formulation stability and surfactant-stabilized insulin formulations derived therefrom
JP4551222B2 (ja) * 2002-11-08 2010-09-22 エフ.ホフマン−ラ ロシュ アーゲー Pparアゴニストとしての置換4−アルコキシオキサゾール誘導体
US7264813B2 (en) * 2003-09-24 2007-09-04 Nikken Sohonsha Corporation Therapeutic uses of Dunaliella powder
CN102389427A (zh) * 2011-10-10 2012-03-28 成都恒瑞制药有限公司 含有罗格列酮和盐酸西替利嗪的固体口服制剂

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997005875A2 (en) * 1995-08-10 1997-02-20 Warner-Lambert Company A method of reducing the amount of exogenous insulin administered to a patient having noninsulin-dependent diabetes mellitus
WO1997010819A1 (en) * 1995-09-18 1997-03-27 Ligand Pharmaceuticals Incorporated Treating niddm with rxr agonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0719140B1 (en) * 1993-09-15 2007-10-31 Daiichi Sankyo Company, Limited Use of thiazolidinediones to prevent or delay onset of niddm

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997005875A2 (en) * 1995-08-10 1997-02-20 Warner-Lambert Company A method of reducing the amount of exogenous insulin administered to a patient having noninsulin-dependent diabetes mellitus
WO1997010819A1 (en) * 1995-09-18 1997-03-27 Ligand Pharmaceuticals Incorporated Treating niddm with rxr agonists

Also Published As

Publication number Publication date
BR9810444A (pt) 2000-09-05
EP0999837A1 (en) 2000-05-17
BG104059A (en) 2000-10-31
PL343123A1 (en) 2001-07-30
JP2002504138A (ja) 2002-02-05
CO4940454A1 (es) 2000-07-24
AR015894A1 (es) 2001-05-30
AP1287A (en) 2004-06-26
AU8216398A (en) 1999-01-04
UY25050A1 (es) 2000-09-29
IL133143A0 (en) 2001-03-19
ID23951A (id) 2000-06-08
UA70299C2 (en) 2004-10-15
OA11517A (en) 2004-02-04
NO996265L (no) 1999-12-17
TW587937B (en) 2004-05-21
SK179399A3 (en) 2000-11-07
GB9712866D0 (en) 1997-08-20
ZA985237B (en) 2000-02-17
MA26511A1 (fr) 2004-12-20
KR20010013843A (ko) 2001-02-26
AP9901718A0 (en) 1999-12-31
CA2294141A1 (en) 1998-12-23
DZ2521A1 (fr) 2003-02-08
IN189723B (enrdf_load_stackoverflow) 2003-04-19
NO996265D0 (no) 1999-12-17
CN1260715A (zh) 2000-07-19
TR199903095T2 (xx) 2000-08-21
EA004800B1 (ru) 2004-08-26
WO1998057636A1 (en) 1998-12-23
AR012997A1 (es) 2000-11-22
EA200000042A1 (ru) 2000-08-28
PE104499A1 (es) 2000-01-13
HUP0003260A3 (en) 2001-12-28
HUP0003260A2 (hu) 2001-05-28

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