AR015894A1 - Uso de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona e insulina para la preparacion de un medicamento y composicion farmaceuticaque contiene dichos compuestos - Google Patents

Uso de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona e insulina para la preparacion de un medicamento y composicion farmaceuticaque contiene dichos compuestos

Info

Publication number
AR015894A1
AR015894A1 ARP980102886A ARP980102886A AR015894A1 AR 015894 A1 AR015894 A1 AR 015894A1 AR P980102886 A ARP980102886 A AR P980102886A AR P980102886 A ARP980102886 A AR P980102886A AR 015894 A1 AR015894 A1 AR 015894A1
Authority
AR
Argentina
Prior art keywords
insulin
amino
methyl
compounds
preparation
Prior art date
Application number
ARP980102886A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of AR015894A1 publication Critical patent/AR015894A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Abstract

Uso de 5-[4-[2-(N-metil-N-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona (compuesto I) e insulina para la preparacion de un medicamento util para eltratamiento de diabetes mellitus y procesos asociados a la diabetes mellitus en un mamífero, que comprende una cantidad eficaz, no toxica y farmacéuticamenteeficaz de compuesto I e insulina a un mamífero con necesidad de ello; y una composicion farmacéutica que contiene dichos compuestos.
ARP980102886A 1997-06-18 1998-06-17 Uso de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona e insulina para la preparacion de un medicamento y composicion farmaceuticaque contiene dichos compuestos AR015894A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9712866.4A GB9712866D0 (en) 1997-06-18 1997-06-18 Novel method of treatment

Publications (1)

Publication Number Publication Date
AR015894A1 true AR015894A1 (es) 2001-05-30

Family

ID=10814527

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP980102886A AR015894A1 (es) 1997-06-18 1998-06-17 Uso de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona e insulina para la preparacion de un medicamento y composicion farmaceuticaque contiene dichos compuestos
ARP980102883A AR012997A1 (es) 1997-06-18 1998-06-17 Uso de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4- diona e insulina para la preparacion de medicamentos, y composicionfarmaceutica que los contiene.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP980102883A AR012997A1 (es) 1997-06-18 1998-06-17 Uso de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4- diona e insulina para la preparacion de medicamentos, y composicionfarmaceutica que los contiene.

Country Status (30)

Country Link
EP (1) EP0999837A1 (es)
JP (1) JP2002504138A (es)
KR (1) KR20010013843A (es)
CN (1) CN1133431C (es)
AP (1) AP1287A (es)
AR (2) AR015894A1 (es)
AU (1) AU8216398A (es)
BG (1) BG104059A (es)
BR (1) BR9810444A (es)
CA (1) CA2294141A1 (es)
CO (1) CO4940454A1 (es)
DZ (1) DZ2521A1 (es)
EA (1) EA004800B1 (es)
GB (1) GB9712866D0 (es)
HU (1) HUP0003260A3 (es)
ID (1) ID23951A (es)
IL (1) IL133143A0 (es)
IN (1) IN189723B (es)
MA (1) MA26511A1 (es)
NO (1) NO996265L (es)
OA (1) OA11517A (es)
PE (1) PE104499A1 (es)
PL (1) PL343123A1 (es)
SK (1) SK179399A3 (es)
TR (1) TR199903095T2 (es)
TW (1) TW587937B (es)
UA (1) UA70299C2 (es)
UY (1) UY25050A1 (es)
WO (1) WO1998057636A1 (es)
ZA (1) ZA985237B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291495B1 (en) * 1997-02-24 2001-09-18 Robert B. Rieveley Method and composition for the treatment of diabetes
TWI249401B (en) 1999-04-14 2006-02-21 Takeda Chemical Industries Ltd Agent for improving ketosis
WO2000064892A2 (en) 1999-04-23 2000-11-02 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
AU5325200A (en) 1999-06-21 2001-01-09 Eli Lilly And Company Synergistic use of thiazolidinediones with glucagon-like peptide-1 and agonists thereof to treat metabolic instability associated with non-insulin dependent diabetes
EP1196189A2 (en) * 1999-06-25 2002-04-17 Medtronic MiniMed, Inc. Multiple agent diabetes therapy
US6468507B1 (en) * 2000-05-01 2002-10-22 Aeropharm Technology, Inc. Non-aqueous aerosol formulation comprising rosiglitazone maleate, a non-aqueous carrier, and an amino acid stabilizer
GB0023970D0 (en) * 2000-09-29 2000-11-15 Smithkline Beecham Plc Novel pharmaceutical
WO2002067969A2 (en) 2001-02-21 2002-09-06 Medtronic Minimed, Inc. Stabilized insulin formulations
US6531461B1 (en) 2001-06-04 2003-03-11 Louis Obyo Obyo Nelson Medicament for the treatment of diabetes
WO2002100396A1 (en) * 2001-06-07 2002-12-19 Wyeth COMBINATION OF A PTPase INHIBITOR AND A THIAZOLIDINEDIONE AGENT
US6737401B2 (en) 2001-06-28 2004-05-18 Metronic Minimed, Inc. Methods of evaluating protein formulation stability and surfactant-stabilized insulin formulations derived therefrom
AU2003276234B2 (en) 2002-11-08 2007-04-19 F. Hoffmann-La Roche Ag Substituted 4-alkoxyoxazol derivatives as PPAR agonists
US7264813B2 (en) * 2003-09-24 2007-09-04 Nikken Sohonsha Corporation Therapeutic uses of Dunaliella powder
CN102389427A (zh) * 2011-10-10 2012-03-28 成都恒瑞制药有限公司 含有罗格列酮和盐酸西替利嗪的固体口服制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU679572B2 (en) * 1993-09-15 1997-07-03 Daiichi Sankyo Company, Limited Use of thiazolidinediones to prevent or delay onset of NIDDM
NZ313874A (en) * 1995-08-10 2000-09-29 Warner Lambert Co Compounds used as medicaments useful in eliminating the amount of exogenous insulin administered to a patient having noninsulin-dependent diabetes mellitus
PT859608E (pt) * 1995-09-18 2004-06-30 Ligand Pharm Inc Tratamento de niddm com agonistas de rxr

Also Published As

Publication number Publication date
BR9810444A (pt) 2000-09-05
JP2002504138A (ja) 2002-02-05
CA2294141A1 (en) 1998-12-23
UA70299C2 (en) 2004-10-15
BG104059A (en) 2000-10-31
OA11517A (en) 2004-02-04
EA004800B1 (ru) 2004-08-26
AP9901718A0 (en) 1999-12-31
IL133143A0 (en) 2001-03-19
PL343123A1 (en) 2001-07-30
AR012997A1 (es) 2000-11-22
MA26511A1 (fr) 2004-12-20
GB9712866D0 (en) 1997-08-20
TR199903095T2 (xx) 2000-08-21
ID23951A (id) 2000-06-08
ZA985237B (en) 2000-02-17
AU8216398A (en) 1999-01-04
CN1260715A (zh) 2000-07-19
EA200000042A1 (ru) 2000-08-28
HUP0003260A3 (en) 2001-12-28
NO996265D0 (no) 1999-12-17
KR20010013843A (ko) 2001-02-26
NO996265L (no) 1999-12-17
TW587937B (en) 2004-05-21
IN189723B (es) 2003-04-19
PE104499A1 (es) 2000-01-13
CO4940454A1 (es) 2000-07-24
EP0999837A1 (en) 2000-05-17
HUP0003260A2 (hu) 2001-05-28
UY25050A1 (es) 2000-09-29
AP1287A (en) 2004-06-26
DZ2521A1 (fr) 2003-02-08
SK179399A3 (en) 2000-11-07
WO1998057636A1 (en) 1998-12-23
CN1133431C (zh) 2004-01-07

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