AR015894A1 - USE OF 5- [4- [2- (N-METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] TIAZOLIDIN-2,4-DIONA AND INSULIN FOR THE PREPARATION OF A MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINS SUCH COMPOUNDS - Google Patents
USE OF 5- [4- [2- (N-METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] TIAZOLIDIN-2,4-DIONA AND INSULIN FOR THE PREPARATION OF A MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINS SUCH COMPOUNDSInfo
- Publication number
- AR015894A1 AR015894A1 ARP980102886A ARP980102886A AR015894A1 AR 015894 A1 AR015894 A1 AR 015894A1 AR P980102886 A ARP980102886 A AR P980102886A AR P980102886 A ARP980102886 A AR P980102886A AR 015894 A1 AR015894 A1 AR 015894A1
- Authority
- AR
- Argentina
- Prior art keywords
- insulin
- amino
- methyl
- compounds
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Uso de 5-[4-[2-(N-metil-N-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona (compuesto I) e insulina para la preparacion de un medicamento util para eltratamiento de diabetes mellitus y procesos asociados a la diabetes mellitus en un mamífero, que comprende una cantidad eficaz, no toxica y farmacéuticamenteeficaz de compuesto I e insulina a un mamífero con necesidad de ello; y una composicion farmacéutica que contiene dichos compuestos.Use of 5- [4- [2- (N-methyl-N- (2-pyridyl) amino) ethoxy] benzyl] thiazolidin-2,4-dione (compound I) and insulin for the preparation of a medicament useful for treatment of diabetes mellitus and processes associated with diabetes mellitus in a mammal, comprising an effective, non-toxic and pharmaceutically effective amount of compound I and insulin to a mammal in need thereof; and a pharmaceutical composition containing said compounds.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9712866.4A GB9712866D0 (en) | 1997-06-18 | 1997-06-18 | Novel method of treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR015894A1 true AR015894A1 (en) | 2001-05-30 |
Family
ID=10814527
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980102886A AR015894A1 (en) | 1997-06-18 | 1998-06-17 | USE OF 5- [4- [2- (N-METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] TIAZOLIDIN-2,4-DIONA AND INSULIN FOR THE PREPARATION OF A MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINS SUCH COMPOUNDS |
| ARP980102883A AR012997A1 (en) | 1997-06-18 | 1998-06-17 | USE OF 5- [4- [2- (N-METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] THIAZOLIDIN-2,4- DIONA AND INSULIN FOR THE PREPARATION OF MEDICINES, AND CONTAINING PHARMACEUTICAL COMPOSITION. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980102883A AR012997A1 (en) | 1997-06-18 | 1998-06-17 | USE OF 5- [4- [2- (N-METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] THIAZOLIDIN-2,4- DIONA AND INSULIN FOR THE PREPARATION OF MEDICINES, AND CONTAINING PHARMACEUTICAL COMPOSITION. |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0999837A1 (en) |
| JP (1) | JP2002504138A (en) |
| KR (1) | KR20010013843A (en) |
| CN (1) | CN1133431C (en) |
| AP (1) | AP1287A (en) |
| AR (2) | AR015894A1 (en) |
| AU (1) | AU8216398A (en) |
| BG (1) | BG104059A (en) |
| BR (1) | BR9810444A (en) |
| CA (1) | CA2294141A1 (en) |
| CO (1) | CO4940454A1 (en) |
| DZ (1) | DZ2521A1 (en) |
| EA (1) | EA004800B1 (en) |
| GB (1) | GB9712866D0 (en) |
| HU (1) | HUP0003260A3 (en) |
| ID (1) | ID23951A (en) |
| IL (1) | IL133143A0 (en) |
| IN (1) | IN189723B (en) |
| MA (1) | MA26511A1 (en) |
| NO (1) | NO996265L (en) |
| OA (1) | OA11517A (en) |
| PE (1) | PE104499A1 (en) |
| PL (1) | PL343123A1 (en) |
| SK (1) | SK179399A3 (en) |
| TR (1) | TR199903095T2 (en) |
| TW (1) | TW587937B (en) |
| UA (1) | UA70299C2 (en) |
| UY (1) | UY25050A1 (en) |
| WO (1) | WO1998057636A1 (en) |
| ZA (1) | ZA985237B (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6291495B1 (en) * | 1997-02-24 | 2001-09-18 | Robert B. Rieveley | Method and composition for the treatment of diabetes |
| TWI249401B (en) | 1999-04-14 | 2006-02-21 | Takeda Chemical Industries Ltd | Agent for improving ketosis |
| AU765498B2 (en) | 1999-04-23 | 2003-09-18 | Smithkline Beecham Plc | Novel pharmaceutical |
| EP1849475A1 (en) | 1999-06-21 | 2007-10-31 | Eli Lilly & Company | Synergistic use of thiazolidinediones with glucagon-like peptide-1 and agonists thereof to treat non-insulin dependent diabetes |
| AU5760900A (en) * | 1999-06-25 | 2001-01-31 | Minimed, Inc. | Multiple agent diabetes therapy |
| US6468507B1 (en) * | 2000-05-01 | 2002-10-22 | Aeropharm Technology, Inc. | Non-aqueous aerosol formulation comprising rosiglitazone maleate, a non-aqueous carrier, and an amino acid stabilizer |
| GB0023970D0 (en) * | 2000-09-29 | 2000-11-15 | Smithkline Beecham Plc | Novel pharmaceutical |
| US6852694B2 (en) | 2001-02-21 | 2005-02-08 | Medtronic Minimed, Inc. | Stabilized insulin formulations |
| US6531461B1 (en) | 2001-06-04 | 2003-03-11 | Louis Obyo Obyo Nelson | Medicament for the treatment of diabetes |
| WO2002100396A1 (en) * | 2001-06-07 | 2002-12-19 | Wyeth | COMBINATION OF A PTPase INHIBITOR AND A THIAZOLIDINEDIONE AGENT |
| US6737401B2 (en) | 2001-06-28 | 2004-05-18 | Metronic Minimed, Inc. | Methods of evaluating protein formulation stability and surfactant-stabilized insulin formulations derived therefrom |
| ATE377419T1 (en) | 2002-11-08 | 2007-11-15 | Hoffmann La Roche | SUBSTITUTED 4-ALKOXYOXAZOLE DERIVATIVES AS PPAR AGONISTS |
| US7264813B2 (en) | 2003-09-24 | 2007-09-04 | Nikken Sohonsha Corporation | Therapeutic uses of Dunaliella powder |
| CN102389427A (en) * | 2011-10-10 | 2012-03-28 | 成都恒瑞制药有限公司 | Solid oral preparation containing rosiglitazone and cetirizine hydrochloride |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2195282C2 (en) * | 1993-09-15 | 2002-12-27 | Санкио Компани Лимитед | Application of thiazolidinediones for prevention or onset postponement of insulin-independent diabetes mellitus (niddm) |
| KR19990036290A (en) * | 1995-08-10 | 1999-05-25 | 로즈 암스트롱 | Reduction of Exogenous Insulin Dosage in Non-insulin-Dependent Diabetic Patients |
| JPH11511472A (en) * | 1995-09-18 | 1999-10-05 | リガンド・ファーマシューティカルズ・インコーポレイテッド | Treatment of NIDDM with RXR agonist |
-
1997
- 1997-06-18 GB GBGB9712866.4A patent/GB9712866D0/en active Pending
-
1998
- 1998-06-15 UA UA99126881A patent/UA70299C2/en unknown
- 1998-06-15 IL IL13314398A patent/IL133143A0/en unknown
- 1998-06-15 ID IDW991627A patent/ID23951A/en unknown
- 1998-06-15 BR BR9810444-6A patent/BR9810444A/en not_active IP Right Cessation
- 1998-06-15 PL PL98343123A patent/PL343123A1/en unknown
- 1998-06-15 CA CA002294141A patent/CA2294141A1/en not_active Abandoned
- 1998-06-15 CN CNB988062232A patent/CN1133431C/en not_active Expired - Fee Related
- 1998-06-15 AP APAP/P/1999/001718A patent/AP1287A/en active
- 1998-06-15 EP EP98932169A patent/EP0999837A1/en not_active Withdrawn
- 1998-06-15 EA EA200000042A patent/EA004800B1/en not_active IP Right Cessation
- 1998-06-15 JP JP50375799A patent/JP2002504138A/en not_active Ceased
- 1998-06-15 TR TR1999/03095T patent/TR199903095T2/en unknown
- 1998-06-15 HU HU0003260A patent/HUP0003260A3/en unknown
- 1998-06-15 WO PCT/EP1998/003692 patent/WO1998057636A1/en not_active Application Discontinuation
- 1998-06-15 KR KR1019997011864A patent/KR20010013843A/en not_active Application Discontinuation
- 1998-06-15 AU AU82163/98A patent/AU8216398A/en not_active Abandoned
- 1998-06-15 SK SK1793-99A patent/SK179399A3/en unknown
- 1998-06-17 ZA ZA9805237A patent/ZA985237B/en unknown
- 1998-06-17 TW TW087109619A patent/TW587937B/en not_active IP Right Cessation
- 1998-06-17 DZ DZ980131A patent/DZ2521A1/en active
- 1998-06-17 MA MA25122A patent/MA26511A1/en unknown
- 1998-06-17 AR ARP980102886A patent/AR015894A1/en not_active Application Discontinuation
- 1998-06-17 AR ARP980102883A patent/AR012997A1/en not_active Application Discontinuation
- 1998-06-18 CO CO98034654A patent/CO4940454A1/en unknown
- 1998-06-18 PE PE1998000535A patent/PE104499A1/en not_active Application Discontinuation
- 1998-06-18 IN IN1698DE1998 patent/IN189723B/en unknown
- 1998-06-18 UY UY25050A patent/UY25050A1/en unknown
-
1999
- 1999-12-17 OA OA9900296A patent/OA11517A/en unknown
- 1999-12-17 NO NO996265A patent/NO996265L/en not_active Application Discontinuation
-
2000
- 2000-01-06 BG BG104059A patent/BG104059A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW587937B (en) | 2004-05-21 |
| UA70299C2 (en) | 2004-10-15 |
| PE104499A1 (en) | 2000-01-13 |
| EP0999837A1 (en) | 2000-05-17 |
| JP2002504138A (en) | 2002-02-05 |
| ID23951A (en) | 2000-06-08 |
| BR9810444A (en) | 2000-09-05 |
| EA004800B1 (en) | 2004-08-26 |
| CA2294141A1 (en) | 1998-12-23 |
| DZ2521A1 (en) | 2003-02-08 |
| WO1998057636A1 (en) | 1998-12-23 |
| PL343123A1 (en) | 2001-07-30 |
| GB9712866D0 (en) | 1997-08-20 |
| AP9901718A0 (en) | 1999-12-31 |
| KR20010013843A (en) | 2001-02-26 |
| NO996265D0 (en) | 1999-12-17 |
| TR199903095T2 (en) | 2000-08-21 |
| EA200000042A1 (en) | 2000-08-28 |
| HUP0003260A2 (en) | 2001-05-28 |
| AP1287A (en) | 2004-06-26 |
| HUP0003260A3 (en) | 2001-12-28 |
| ZA985237B (en) | 2000-02-17 |
| CO4940454A1 (en) | 2000-07-24 |
| AU8216398A (en) | 1999-01-04 |
| UY25050A1 (en) | 2000-09-29 |
| BG104059A (en) | 2000-10-31 |
| AR012997A1 (en) | 2000-11-22 |
| CN1133431C (en) | 2004-01-07 |
| IN189723B (en) | 2003-04-19 |
| OA11517A (en) | 2004-02-04 |
| IL133143A0 (en) | 2001-03-19 |
| MA26511A1 (en) | 2004-12-20 |
| NO996265L (en) | 1999-12-17 |
| SK179399A3 (en) | 2000-11-07 |
| CN1260715A (en) | 2000-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |