HUP0301799A2 - 5-[4-{2-[N-metil-N-(2-piridil)-amino]-etoxi}-benzil]-2,4-dioxo-tiazolidin-hidrojodid alkalmazása diabetetes mellitus kezelésére, eljárás a vegyület előállítására és ezt tartalmazó gyógyszerkészítmény - Google Patents

5-[4-{2-[N-metil-N-(2-piridil)-amino]-etoxi}-benzil]-2,4-dioxo-tiazolidin-hidrojodid alkalmazása diabetetes mellitus kezelésére, eljárás a vegyület előállítására és ezt tartalmazó gyógyszerkészítmény

Info

Publication number
HUP0301799A2
HUP0301799A2 HU0301799A HUP0301799A HUP0301799A2 HU P0301799 A2 HUP0301799 A2 HU P0301799A2 HU 0301799 A HU0301799 A HU 0301799A HU P0301799 A HUP0301799 A HU P0301799A HU P0301799 A2 HUP0301799 A2 HU P0301799A2
Authority
HU
Hungary
Prior art keywords
thiazolidine
pyridyl
ethoxy
benzyl
amino
Prior art date
Application number
HU0301799A
Other languages
English (en)
Inventor
Andrew Simon Craig
Tim Chien Ting Ho
Michael John Millan
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Publication of HUP0301799A2 publication Critical patent/HUP0301799A2/hu
Publication of HUP0301799A3 publication Critical patent/HUP0301799A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A találmány az 5-[4-{2-[N-metil-N-(2-piridil)-amino]-etoxi}-benzil]-2,4-dioxo-tiazolidin-hidrojodidra és szolvátjaira mint újgyógyszerhatóanyagra, a gyógyszerhatóanyag előállítási eljárására, agyógyszerhatóanyagot tartalmazó gyógyszerkészítményekre, valamint agyógyszerhatóanyag gyógyászati alkalmazására vonatkozik. Ó
HU0301799A 2000-06-08 2001-06-08 Use of 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione hydriodide for treating diabetes mellitus, process for preparation thereof and pharmaceutical composition containing the same HUP0301799A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0014005.3A GB0014005D0 (en) 2000-06-08 2000-06-08 Novel pharmaceutical
PCT/GB2001/002545 WO2001094343A1 (en) 2000-06-08 2001-06-08 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione hydriodide as pharmaceutical

Publications (2)

Publication Number Publication Date
HUP0301799A2 true HUP0301799A2 (hu) 2003-12-29
HUP0301799A3 HUP0301799A3 (en) 2005-04-28

Family

ID=9893256

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301799A HUP0301799A3 (en) 2000-06-08 2001-06-08 Use of 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione hydriodide for treating diabetes mellitus, process for preparation thereof and pharmaceutical composition containing the same

Country Status (26)

Country Link
US (1) US20040024027A1 (hu)
EP (1) EP1292595A1 (hu)
JP (1) JP2003535861A (hu)
KR (1) KR20030007919A (hu)
CN (1) CN1443185A (hu)
AP (1) AP2002002684A0 (hu)
AU (2) AU2001262550B2 (hu)
BG (1) BG107356A (hu)
BR (1) BR0111508A (hu)
CA (1) CA2411064A1 (hu)
CZ (1) CZ20024029A3 (hu)
DZ (1) DZ3383A1 (hu)
EA (1) EA004298B1 (hu)
GB (1) GB0014005D0 (hu)
HU (1) HUP0301799A3 (hu)
IL (1) IL153280A0 (hu)
MA (1) MA26912A1 (hu)
MX (1) MXPA02012173A (hu)
NO (1) NO20025882L (hu)
NZ (1) NZ522997A (hu)
OA (1) OA12283A (hu)
PL (1) PL363683A1 (hu)
SK (1) SK17152002A3 (hu)
WO (1) WO2001094343A1 (hu)
YU (1) YU93002A (hu)
ZA (1) ZA200300017B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39384E1 (en) 1993-09-01 2006-11-07 Smithkline Beecham P.L.C. Substituted thiazolidinedione derivatives
DE102005034406A1 (de) * 2005-07-22 2007-02-01 Ratiopharm Gmbh Neue Salze von Rosiglitazon
US7435741B2 (en) * 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856378T2 (de) * 1987-09-04 2000-05-11 Beecham Group Plc Substituierte Thiazolidindionderivate
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
GB9726563D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726568D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726566D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9909041D0 (en) * 1999-04-20 1999-06-16 Smithkline Beecham Plc Novel pharmaceutical
GB9909075D0 (en) * 1999-04-20 1999-06-16 Smithkline Beecham Plc Novel pharmaceutical

Also Published As

Publication number Publication date
NO20025882D0 (no) 2002-12-06
CN1443185A (zh) 2003-09-17
WO2001094343A1 (en) 2001-12-13
EA004298B1 (ru) 2004-02-26
MXPA02012173A (es) 2003-04-25
SK17152002A3 (sk) 2003-05-02
JP2003535861A (ja) 2003-12-02
EA200300004A1 (ru) 2003-04-24
IL153280A0 (en) 2003-07-06
KR20030007919A (ko) 2003-01-23
HUP0301799A3 (en) 2005-04-28
BR0111508A (pt) 2003-03-25
CZ20024029A3 (cs) 2003-04-16
GB0014005D0 (en) 2000-08-02
EP1292595A1 (en) 2003-03-19
PL363683A1 (en) 2004-11-29
US20040024027A1 (en) 2004-02-05
YU93002A (sh) 2006-01-16
AU6255001A (en) 2001-12-17
CA2411064A1 (en) 2001-12-13
DZ3383A1 (fr) 2001-12-13
OA12283A (en) 2003-11-10
ZA200300017B (en) 2004-04-08
AP2002002684A0 (en) 2002-12-31
NO20025882L (no) 2003-01-29
MA26912A1 (fr) 2004-12-20
AU2001262550B2 (en) 2004-04-22
NZ522997A (en) 2004-05-28
BG107356A (bg) 2003-06-30

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees