CN111542596B - 产生工程化细胞的治疗性组合物的方法 - Google Patents
产生工程化细胞的治疗性组合物的方法 Download PDFInfo
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- CN111542596B CN111542596B CN201880084155.4A CN201880084155A CN111542596B CN 111542596 B CN111542596 B CN 111542596B CN 201880084155 A CN201880084155 A CN 201880084155A CN 111542596 B CN111542596 B CN 111542596B
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- A61K40/10—Cellular immunotherapy characterised by the cell type used
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- A61K40/00—Cellular immunotherapy
- A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
- A61K40/31—Chimeric antigen receptors [CAR]
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- A61K40/41—Vertebrate antigens
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- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762580409P | 2017-11-01 | 2017-11-01 | |
| US62/580,409 | 2017-11-01 | ||
| US201762596771P | 2017-12-08 | 2017-12-08 | |
| US62/596,771 | 2017-12-08 | ||
| US201862721603P | 2018-08-22 | 2018-08-22 | |
| US62/721,603 | 2018-08-22 | ||
| PCT/US2018/058590 WO2019089855A1 (en) | 2017-11-01 | 2018-10-31 | Process for generating therapeutic compositions of engineered cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111542596A CN111542596A (zh) | 2020-08-14 |
| CN111542596B true CN111542596B (zh) | 2025-01-14 |
Family
ID=64362686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880084155.4A Active CN111542596B (zh) | 2017-11-01 | 2018-10-31 | 产生工程化细胞的治疗性组合物的方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US12258580B2 (https=) |
| EP (2) | EP3704230B1 (https=) |
| JP (2) | JP7357626B2 (https=) |
| KR (1) | KR20200099132A (https=) |
| CN (1) | CN111542596B (https=) |
| AU (2) | AU2018360599A1 (https=) |
| BR (1) | BR112020008340A2 (https=) |
| CA (1) | CA3084514A1 (https=) |
| DK (1) | DK3704230T3 (https=) |
| ES (1) | ES2999361T3 (https=) |
| FI (1) | FI3704230T3 (https=) |
| IL (1) | IL274293B2 (https=) |
| MA (1) | MA50855A (https=) |
| MX (1) | MX2020004240A (https=) |
| PL (1) | PL3704230T3 (https=) |
| PT (1) | PT3704230T (https=) |
| SG (1) | SG11202003688PA (https=) |
| WO (1) | WO2019089855A1 (https=) |
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| RU2763795C2 (ru) | 2014-04-23 | 2022-01-11 | Джуно Терапьютикс, Инк. | Способы выделения, культивирования и генетической инженерии популяций клеток иммунной системы для адоптивной терапии |
| WO2019113557A1 (en) | 2017-12-08 | 2019-06-13 | Juno Therapeutics, Inc. | Process for producing a composition of engineered t cells |
| JP7433230B2 (ja) | 2017-12-08 | 2024-02-19 | ジュノー セラピューティクス インコーポレイテッド | 細胞を培養するための無血清培地配合物およびその使用の方法 |
| CN113474450A (zh) | 2018-08-09 | 2021-10-01 | 朱诺治疗学股份有限公司 | 产生工程化细胞的方法以及所述工程化细胞的组合物 |
| KR20210104713A (ko) | 2018-11-16 | 2021-08-25 | 주노 쎄러퓨티크스 인코퍼레이티드 | B 세포 악성 종양 치료를 위한 조작된 t 세포 투약 방법 |
| KR102624804B1 (ko) * | 2018-11-16 | 2024-01-12 | 에프. 호프만-라 로슈 아게 | 결합 쌍의 부재를 갖는 스트렙타비딘 코팅된 고체상 |
| PL3886894T3 (pl) | 2018-11-30 | 2024-07-01 | Juno Therapeutics, Inc. | Metody dawkowania i leczenia nowotworów b-komórkowych w adoptywnej terapii komórkowej |
| PL3886875T3 (pl) | 2018-11-30 | 2024-09-09 | Juno Therapeutics, Inc. | Metody leczenia z wykorzystaniem adoptywnej terapii komórkowej |
| KR20220004028A (ko) * | 2019-04-26 | 2022-01-11 | 알로젠 테라퓨틱스 인코포레이티드 | 동종 car t 세포를 제조하는 방법 |
| CA3142108A1 (en) * | 2019-05-28 | 2020-12-03 | Miltenyi Biotec B.V. & Co. KG | Method for generation of genetically modified t cells |
| US20220412954A1 (en) | 2019-11-05 | 2022-12-29 | Juno Therapeutics, Inc. | Methods of determining attributes of therapeutic t cell compositions |
| IL293393A (en) | 2019-12-06 | 2022-07-01 | Juno Therapeutics Inc | Cell therapy-related toxicity and response-related methods for the treatment of b-cell malignancies |
| JP2023513434A (ja) | 2020-01-24 | 2023-03-31 | ジュノー セラピューティクス インコーポレイテッド | 養子細胞療法における投与ならびに濾胞性リンパ腫および辺縁帯リンパ腫の処置のための方法 |
| US20230201440A1 (en) * | 2020-05-08 | 2023-06-29 | Innovative Cellular Therapeutics Holdings, Ltd. | System and method for gene and/or cellular therapy |
| JP7727662B2 (ja) | 2020-05-13 | 2025-08-21 | ジュノー セラピューティクス インコーポレイテッド | 臨床応答に関連する特徴量の特定方法およびその使用 |
| AU2022227686A1 (en) | 2021-02-25 | 2023-07-27 | Lyell Immunopharma, Inc. | Ror1 targeting chimeric antigen receptor |
| KR20230159851A (ko) | 2021-03-22 | 2023-11-22 | 주노 쎄러퓨티크스 인코퍼레이티드 | 치료 세포 조성물의 효력을 결정하는 방법 |
| TWI828009B (zh) * | 2021-11-19 | 2024-01-01 | 財團法人工業技術研究院 | 免標記式細胞活性檢測的方法及訓練人工智慧執行免標記式細胞活性檢測的方法 |
| WO2023230548A1 (en) | 2022-05-25 | 2023-11-30 | Celgene Corporation | Method for predicting response to a t cell therapy |
| EP4543923A1 (en) | 2022-06-22 | 2025-04-30 | Juno Therapeutics, Inc. | Treatment methods for second line therapy of cd19-targeted car t cells |
| CN121100267A (zh) | 2022-12-09 | 2025-12-09 | 朱诺治疗学股份有限公司 | 使用全息成像预测细胞表型的机器学习方法 |
| KR20260005874A (ko) | 2023-02-28 | 2026-01-12 | 주노 쎄러퓨티크스 인코퍼레이티드 | 전신 자가면역 질환을 치료하기 위한 세포 요법 |
| KR20250169631A (ko) | 2023-04-18 | 2025-12-03 | 주노 쎄러퓨티크스 인코퍼레이티드 | 치료 세포 조성물의 효력을 평가하기 위한 세포독성 검정 |
| WO2024226858A1 (en) | 2023-04-26 | 2024-10-31 | Juno Therapeutics, Inc. | Methods for viral vector manufacturing |
| CN121464348A (zh) | 2023-05-23 | 2026-02-03 | 朱诺治疗学股份有限公司 | T细胞的激活标记物和评估t细胞激活的方法 |
| WO2025024310A2 (en) * | 2023-07-21 | 2025-01-30 | Kyverna Therapeutics, Inc. | Methods for rapid manufacture of engineered t cells expressing chimeric antigen receptors |
| KR102684935B1 (ko) * | 2024-02-22 | 2024-07-17 | 유진산업개발 주식회사 | 폴리우레아 수지 방수제 및 이를 이용한 방수 공법 |
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| CN119424317A (zh) * | 2024-11-14 | 2025-02-14 | 山东大学 | 一种小鼠干性car-t细胞及其水凝胶细胞库的制备 |
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Also Published As
| Publication number | Publication date |
|---|---|
| MA50855A (fr) | 2020-09-09 |
| FI3704230T3 (fi) | 2024-12-27 |
| EP3704230A1 (en) | 2020-09-09 |
| KR20200099132A (ko) | 2020-08-21 |
| IL274293B2 (en) | 2025-11-01 |
| JP2023182652A (ja) | 2023-12-26 |
| IL274293B1 (en) | 2025-07-01 |
| EP4512823A3 (en) | 2025-05-14 |
| MX2020004240A (es) | 2020-09-25 |
| JP7850117B2 (ja) | 2026-04-22 |
| CN111542596A (zh) | 2020-08-14 |
| JP7357626B2 (ja) | 2023-10-06 |
| ES2999361T3 (en) | 2025-02-25 |
| WO2019089855A1 (en) | 2019-05-09 |
| JP2021501604A (ja) | 2021-01-21 |
| BR112020008340A2 (pt) | 2020-11-17 |
| AU2018360599A1 (en) | 2020-05-07 |
| PL3704230T3 (pl) | 2025-02-24 |
| CA3084514A1 (en) | 2019-05-09 |
| DK3704230T3 (da) | 2025-01-02 |
| US20250171739A1 (en) | 2025-05-29 |
| IL274293A (en) | 2020-06-30 |
| EP4512823A2 (en) | 2025-02-26 |
| AU2025205183A1 (en) | 2025-08-07 |
| US20200354677A1 (en) | 2020-11-12 |
| US12258580B2 (en) | 2025-03-25 |
| SG11202003688PA (en) | 2020-05-28 |
| EP3704230B1 (en) | 2024-10-23 |
| PT3704230T (pt) | 2024-11-19 |
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