CN109846771A - A kind of composition of plant extracts and preparation method thereof with acne-removing - Google Patents
A kind of composition of plant extracts and preparation method thereof with acne-removing Download PDFInfo
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- CN109846771A CN109846771A CN201810729464.4A CN201810729464A CN109846771A CN 109846771 A CN109846771 A CN 109846771A CN 201810729464 A CN201810729464 A CN 201810729464A CN 109846771 A CN109846771 A CN 109846771A
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Abstract
The present invention relates to cosmetic technical fields, more particularly to a kind of composition of plant extracts and preparation method thereof with acne-removing, on the basis of the composition of plant extracts gross mass with acne-removing, the composition of plant extracts with acne-removing includes the component of following mass percentage: granatum 1 ~ 98%, magnolia bark 1 ~ 98% and mangosteen pericarp 1 ~ 98%.The present invention takes into account the effect of efficient oil-control, potent anti-inflammatory, and skin irritation is small；At low cost, simple process, product quality are controllably stablized；It is of light color, smell is light, wide without obvious formula taboo, application, natural safety meets the needs of consumer is for really pressing down acne product for resolving poxes conscientiously.
Description
Technical field
The present invention relates to cosmetic technical field more particularly to a kind of composition of plant extracts with acne-removing and
Preparation method.
Background technique
Acne (also known as whelk) is used as a kind of damage capacitive skin lesion, makes to vast teen-age quality of the life and mental health
Age bracket at influence, and acne effect also extended to 30 ~ 40 years old.In order to meet the needs of remissive treatment acne, manyization
Cosmetic company and hospital release preparation in respective product or institute.Wherein cosmetics company's product is mostly that the concept of without effect produces
Product, even the product of well-known producer, leading ingredient to be added is salicylic acid, Pi Aoning, the disadvantage is that acting on single, irritation
By force, rebound is big；In contrast, preparation (Western medicine is mostly steroids) complicated component, quality controllability are poor, big in the Chinese medicine institute of hospital
Content of starting materials (especially rare medicinal herbs) supply bottleneck can not be mass produced, in addition color is deep, smell remakes into people and uses meaning
It is willing to low, makes its application range critical constraints.
Summary of the invention
The present invention provides one kind and takes into account efficient oil-control, strong to solve the problems, such as above-mentioned traditional product for resolving poxes
Anti-inflammatory effect is imitated, skin irritation is small, of light color, smell is light, the plant with acne-removing without obvious formula taboo mentions
Take compositions.
The present invention also provides the controllably stable plants with acne-removing of a kind of at low cost, simple process, product quality
The preparation method of object extractive composition.
To achieve the goals above, the invention adopts the following technical scheme:
A kind of composition of plant extracts with acne-removing, with the composition of plant extracts gross mass with acne-removing
On the basis of, the composition of plant extracts with acne-removing includes the component of following mass percentage: granatum 1 ~
98%, magnolia bark 1 ~ 98% and mangosteen pericarp 1 ~ 98%.
A kind of preparation method of the composition of plant extracts with acne-removing, comprising the following steps:
(1) granatum, magnolia bark and mangosteen pericarp are weighed according to said ratio, with ethanol water in 30 ~ 80 DEG C of temperature strips
Soak extraction under part, obtains ethanol extract；
(2) ethanol extract filtering, the concentration obtained step (1), purifying elution obtain eluent；
(3) chitosan solution is added under the conditions of 45 ~ 70 DEG C of temperature in the eluent that step (2) obtains, stirred evenly, then added
Enter active carbon, stir evenly, stands 12h, collect to obtain the first supernatant；
(4) the first supernatant liquid filtering obtained by step (3) is concentrated, 1,3-BDO is added, stirs evenly, stand 12-36h, received
Collect to obtain the second supernatant；
(5) the second supernatant is centrifuged, obtains centrifuged supernatant to get the plant extracts group with acne-removing
Close object.
The present invention, which is prepared for one kind with granatum, magnolia bark and mangosteen pericarp (mangosteen skin) these three ingredients, really to be had
Press down the multifunctional plant extractive composition of acne acne-removing.Firstly, this three has been completed rule as industrial crops now
Modelling plantation, raw material supply are sufficient.Wherein granatum and mangosteen pericarp are that fruit pomegranate and mangosteen abandon or adopt pericarp, it may be said that
It is " turning waste into wealth ", increases the secondary use of crops.Secondly, not interacting between the dominant chemical of these three ingredients
The substance for generating toxicity or strong and stimulating, does not need that other Multiple components are added as Chinese medicinal formulae in this way, in this way can be
Guarantee to reduce cost under the premise of effect, simplify technique.Third passes through above-mentioned life although the present invention is plant composition
Production. art can obtain quality controllable, effect and be formulated the not defeated product in synthesis Effect raw material of application, and safety, environmental protection
Property is better than synthesis material.The present invention can be described as that the product of getting up will be merged the advantages of preparation in institute and synthesis material.
Preferably, the percent by volume of the ethanol water is 10 ~ 80% in step (1).
Preferably, the additive amount of the ethanol water is granatum, magnolia bark and mangosteen pericarp gross mass 5 ~
20 times.
Preferably, extraction time is 1 ~ 3 time in step (1), the time control of each soak extraction merges in 2 ~ 48h
Ethanol extract.
Preferably, cycles of concentration is 10 ~ 50 times in step (2)；Purify the process conditions of elution are as follows: inhale using macropore
Attached resin is purified, and eluant, eluent used in elution step is the ethanol water that percent by volume is 10 ~ 95%.
Preferably, in step (3), the preparation steps of the chitosan solution are as follows: 0.5 ~ 2.0g chitosan is added
It is stirred evenly in 100mL glacial acetic acid aqueous solution, 1mL glacial acetic acid is contained in the glacial acetic acid aqueous solution.
Preferably, the additional amount of the chitosan solution is the 1.0 ~ 6.0% of eluent in step (3).
Preferably, cycles of concentration is 10 ~ 20 times in step (4)；The additive amount of the 1,3 butylene glycol is eluting liquid
Long-pending 0.5 ~ 3 times.
Therefore, the invention has the following beneficial effects:
(1) in terms of effect: while in addition to keeping conventional splendid antibacterial action, taking into account the effect of efficient oil-control, potent anti-inflammatory, skin
Skin irritation is small；
(2) production aspect: at low cost, simple process, product quality are controllably stablized；.
(3) formula application: of light color, smell is light, wide without obvious formula taboo, application, natural safety meets conscientiously and disappears
Expense person is for really pressing down the demand of acne product for resolving poxes.
Specific embodiment
Below by specific embodiment, the technical solutions of the present invention will be further described.
In the present invention, if not refering in particular to, all devices and raw material is commercially available or the industry is common are following
Method in embodiment is unless otherwise instructed conventional method in that art.
Embodiment 1
(1) raw material 100g: granatum 1g is weighed according to following quality proportioning, magnolia bark 1g and mangosteen pericarp 98g, with 500g body
The ethanol water that product percentage is 80% soak extraction under the conditions of 80 DEG C of temperature, extraction time are 1 time, each soak extraction
Time control in 48h, merge to obtain ethanol extract；
(2) ethanol extract that step (1) obtains filtered, be concentrated into 10 times, purifying elution is carried out using macroporous absorbent resin,
Eluant, eluent used in elution step is the ethanol water that percent by volume is 10%, obtains eluent；
(3) 0.5g chitosan is added in the 100mL glacial acetic acid aqueous solution containing 1mL glacial acetic acid and is stirred evenly, chitosan is made
Solution；1.0% chitosan solution of eluent is added in the eluent that step (2) is obtained under the conditions of 45 DEG C of temperature, and stirring is equal
It is even, active carbon is then added, stirs evenly, stands 12h, collects to obtain the first supernatant；
(4) the first supernatant liquid filtering obtained by step (3) is concentrated into 10 times, 0.5 times of 1,3- fourth two of effluent volume is added
Alcohol stirs evenly, and stands 12h, collects to obtain the second supernatant；
(5) the second supernatant is centrifuged, obtains centrifuged supernatant to get the plant extracts group with acne-removing
Close object.
Embodiment 2
(1) raw material 100g: granatum 98g is weighed according to following quality proportioning, magnolia bark 1g and mangosteen pericarp 1g use 2000g
Percent by volume be 10% ethanol water under the conditions of 30 DEG C of temperature soak extraction, extraction time be 3 times, every time impregnate
The time of extraction controls in 2h, merges to obtain ethanol extract；
(2) ethanol extract that step (1) obtains filtered, be concentrated into 50 times, purifying elution is carried out using macroporous absorbent resin,
Eluant, eluent used in elution step is the ethanol water that percent by volume is 95%, obtains eluent；
(3) 2.0g chitosan is added in the 100mL glacial acetic acid aqueous solution containing 1mL glacial acetic acid and is stirred evenly, chitosan is made
Solution；6.0% chitosan solution of eluent is added in the eluent that step (2) is obtained under the conditions of 70 DEG C of temperature, and stirring is equal
It is even, active carbon is then added, stirs evenly, stands 12h, collects to obtain the first supernatant；
(4) the first supernatant liquid filtering obtained by step (3) is concentrated into 20 times, 3 times of 1,3-BDO of effluent volume is added,
It stirs evenly, stands 36h, collect to obtain the second supernatant；
(5) the second supernatant is centrifuged, obtains centrifuged supernatant to get the plant extracts group with acne-removing
Close object.
Embodiment 3
(1) raw material 100g: granatum 1g is weighed according to following quality proportioning, magnolia bark 98g and mangosteen pericarp 1g use 1000g
The ethanol water that percent by volume is 65% soak extraction under the conditions of 55 DEG C of temperature, extraction time are 2 times, impregnate mention every time
The time control taken for 24 hours, is merging to obtain ethanol extract；
(2) ethanol extract that step (1) obtains filtered, be concentrated into 30 times, purifying elution is carried out using macroporous absorbent resin,
Eluant, eluent used in elution step is the ethanol water that percent by volume is 55%, obtains eluent；
(3) 1.5g chitosan is added in the 100mL glacial acetic acid aqueous solution containing 1mL glacial acetic acid and is stirred evenly, chitosan is made
Solution；2.5% chitosan solution of eluent is added in the eluent that step (2) is obtained under the conditions of 50 DEG C of temperature, and stirring is equal
It is even, active carbon is then added, stirs evenly, stands 12h, collects to obtain the first supernatant；
(4) the first supernatant liquid filtering obtained by step (3) is concentrated into 15 times, 2 times of 1,3-BDO of effluent volume is added,
It stirs evenly, stands for 24 hours, collect to obtain the second supernatant；
(5) the second supernatant is centrifuged, obtains centrifuged supernatant to get the plant extracts group with acne-removing
Close object.
Embodiment 4
(1) raw material 100g: granatum 10g is weighed according to following quality proportioning, magnolia bark 50g and mangosteen pericarp 40g are used
The ethanol water that 1500g percent by volume is 75% soak extraction under the conditions of 45 DEG C of temperature, extraction time are 3 times, are soaked every time
The time that bubble extracts controls in 40h, merges to obtain ethanol extract；
(2) ethanol extract that step (1) obtains filtered, be concentrated into 40 times, purifying elution is carried out using macroporous absorbent resin,
Eluant, eluent used in elution step is the ethanol water that percent by volume is 20%, obtains eluent；
(3) 1.0g chitosan is added in the 100mL glacial acetic acid aqueous solution containing 1mL glacial acetic acid and is stirred evenly, chitosan is made
Solution；4.5% chitosan solution of eluent is added in the eluent that step (2) is obtained under the conditions of 45 DEG C of temperature, and stirring is equal
It is even, active carbon is then added, stirs evenly, stands 12h, collects to obtain the first supernatant；
(4) the first supernatant liquid filtering obtained by step (3) is concentrated into 10 times, 1.5 times of 1,3- fourth two of effluent volume is added
Alcohol stirs evenly, and stands 30h, collects to obtain the second supernatant；
(5) the second supernatant is centrifuged, obtains centrifuged supernatant to get the plant extracts group with acne-removing
Close object.
Comparative example
Using commercially available anti-acne face cleaning milk product.
The composition of plant extracts with acne-removing of embodiment 1-4 is equipped with suitable water and face cleaning is made in auxiliary agent
Cream, the commercially available anti-acne face cleaning milk product with comparative example transfer to 50 patients with acne to use respectively, sooner or later primary, and tracking and testing
Its effect, the results are shown in Table 1.
Test method and effect standard
(1) " new Chinese medicine guideline of clinical investigations " is referred to, Evaluation of Synthetic Effect of Holistic is with skin lesion degree, skin lesion distribution, symptom, body
The total mark of sign calculates curative effect rate.
Skin lesion counts * 100% to curative effect=(skin lesion counts after skin lesion counting-treatment before treating)/before treating.
It cures: 90% or more skin lesion recession, only a little pigmentation；
Effective: skin lesion recession 60% ~ 90%, symptom mitigates；
Effective: skin lesion recession 20% ~ 60%, symptom improves；
Invalid: skin lesion recession < 20%, clinical symptoms do not improve.
Total effective rate=cure rate+obvious effective rate+effective percentage.
(2) fat secretion reduction amount is tested: is detected respectively before using product and using product with grease measuring instrument for 24 hours
Afterwards, skin surface fat content calculates the reduction amount of skin surface fat content, is averaged.
(3) lasting fat secretion reduction amount: continuous use product 1 week is contained with grease measuring instrument detection skin surface grease
Amount deactivates product, after waiting 28 days, then detects skin surface fat content, calculate the lasting fat secretion reduction amount of skin, make even
Mean value.
(4) it cures the time of acne: using product, sight is looked into the healing time used, is averaged.
1. testing result of table
| Performance indicator | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Comparative example |
| Healing number | 30 | 28 | 33 | 32 | 20 |
| Cure rate | 60% | 56% | 66% | 62% | 40% |
| Effective number | 15 | 19 | 12 | 11 | 14 |
| Obvious effective rate | 30% | 38% | 24% | 20% | 28% |
| Efficiently individual quantity | 2 | 2 | 4 | 5 | 8 |
| It is efficient | 4% | 4% | 8% | 10% | 16% |
| Invalid number | 3 | 1 | 1 | 2 | 8 |
| Inefficiency | 6% | 2% | 2% | 4% | 16% |
| Total effective rate | 94% | 98% | 98% | 96% | 84% |
| Fat secretion reduction amount | 35% | 40% | 30% | 38% | 23% |
| Lasting fat secretion reduction amount | 80% | 85% | 87% | 78% | 50% |
| It cures in acne time (day) | 6 | 5 | 4 | 7 | 15 |
As can be seen from Table 1, it is directly applied to using the facial cleanser of the composition of plant extracts containing the present invention with acne-removing
Suffer from acne skin surface, is easy by human skin absorption and utilization and noresidue, to effectively reach oil suction oil-control, eliminate small pox
And to damaged before, the skin of acne scar is effectively repaired, permanence operation is more preferably；Its safety is much higher than with mildness
Presently commercially available product, by experiments have shown that the ability that the present invention adjusts skin fat secretion from the root is higher than presently commercially available production
Product, and presently commercially available product is equally better than for the effect and time of curing acne, it is of light color, smell is light, without obviously matching
Side's taboo, application are wide, and natural safety meets the needs of consumer is for really pressing down acne product for resolving poxes conscientiously.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the present invention in any form, and is not surpassing
There are also other variations and modifications under the premise of technical solution documented by claim out.
Claims (9)
1. a kind of composition of plant extracts with acne-removing, which is characterized in that with the plant extract with acne-removing
On the basis of compositions gross mass, the composition of plant extracts with acne-removing includes following mass percentage
Component: granatum 1 ~ 98%, magnolia bark 1 ~ 98% and mangosteen pericarp 1 ~ 98%.
2. a kind of preparation method of the composition of plant extracts with acne-removing as described in claim 1, feature exist
In, comprising the following steps:
(1) granatum, magnolia bark and mangosteen pericarp are weighed according to said ratio, with ethanol water in 30 ~ 80 DEG C of temperature strips
Soak extraction under part, obtains ethanol extract；
(2) ethanol extract filtering, the concentration obtained step (1), purifying elution obtain eluent；
(3) chitosan solution is added under the conditions of 45 ~ 70 DEG C of temperature in the eluent that step (2) obtains, stirred evenly, then added
Enter active carbon, stir evenly, stands 12h, collect to obtain the first supernatant；
(4) the first supernatant liquid filtering obtained by step (3) is concentrated, 1,3-BDO is added, stirs evenly, stand 12-36h, received
Collect to obtain the second supernatant；
(5) the second supernatant is centrifuged, obtains centrifuged supernatant to get the plant extracts group with acne-removing
Close object.
3. a kind of composition of plant extracts with acne-removing according to claim 2, which is characterized in that step
(1) in, the percent by volume of the ethanol water is 10 ~ 80%.
4. a kind of composition of plant extracts with acne-removing according to claim 2, which is characterized in that step
(1) in, the additive amount of the ethanol water is granatum, 5 ~ 20 times of magnolia bark and mangosteen pericarp gross mass.
5. a kind of composition of plant extracts with acne-removing according to claim 2, which is characterized in that step
(1) in, extraction time is 1 ~ 3 time, and the time control of each soak extraction merges ethanol extract in 2 ~ 48h.
6. a kind of composition of plant extracts with acne-removing according to claim 2, which is characterized in that step
(2) in, cycles of concentration is 10 ~ 50 times；Purify the process conditions of elution are as follows: purified using macroporous absorbent resin, elution step
Rapid eluant, eluent used is the ethanol water that percent by volume is 10 ~ 95%.
7. a kind of composition of plant extracts with acne-removing according to claim 2, which is characterized in that step
(3) in, the preparation steps of the chitosan solution are as follows: 0.5 ~ 2.0g chitosan is added in 100mL glacial acetic acid aqueous solution and stirs
Uniformly, 1mL glacial acetic acid is contained in the glacial acetic acid aqueous solution.
8. a kind of composition of plant extracts with acne-removing according to claim 2 or 7, which is characterized in that step
Suddenly in (3), the additional amount of the chitosan solution is the 1.0 ~ 6.0% of eluent.
9. a kind of composition of plant extracts with acne-removing according to claim 2, which is characterized in that step
(4) in, cycles of concentration is 10 ~ 20 times；The additive amount of the 1,3 butylene glycol is 0.5 ~ 3 times of effluent volume.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110522687A (en) * | 2019-08-22 | 2019-12-03 | 广州市茗妍化妆品有限公司 | A kind of anti-acne shin moisturizer and preparation method thereof |
| CN112675087A (en) * | 2020-12-31 | 2021-04-20 | 肇庆迪彩日化科技有限公司 | Plant antibacterial and bacteriostatic scalp care composition and preparation method and application thereof |
| CN112870131A (en) * | 2021-03-31 | 2021-06-01 | 深圳市萱嘉生物科技有限公司 | Traditional Chinese medicine extract composition with acne removing effect and preparation method thereof |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1143442A (en) * | 1997-07-25 | 1999-02-16 | Lotte Co Ltd | Legionella bacteria resistant composition |
| CN105687032A (en) * | 2016-02-03 | 2016-06-22 | 湖南朗林生物制品有限公司 | Natural composition for improving health condition of skin |
| CN105833187A (en) * | 2016-05-14 | 2016-08-10 | 广东轻工职业技术学院 | Botanical medicine composition with acne removing effect and application |
| CN107595690A (en) * | 2017-09-01 | 2018-01-19 | 杨仁荷 | Anti-acne essence and preparation method thereof |
| CN107753341A (en) * | 2017-10-31 | 2018-03-06 | 广州赛莱拉干细胞科技股份有限公司 | A kind of moisturizing is releived skin care item and preparation method thereof |
| CN107789253A (en) * | 2017-10-31 | 2018-03-13 | 广州赛莱拉干细胞科技股份有限公司 | A kind of anti-acne moisturizing skin care item and preparation method thereof |
| CN107865803A (en) * | 2017-12-18 | 2018-04-03 | 佛山市汇汾化妆品科技有限公司 | One kind preventing and treating acne composition |
| CN107898681A (en) * | 2017-11-17 | 2018-04-13 | 珠海姗拉娜化妆品有限公司 | A kind of Novel acne treatment naturally extracts composition, acne eliminating cream and preparation method thereof |
| CN107937176A (en) * | 2017-11-30 | 2018-04-20 | 宁波秋日小城智能科技有限公司 | A kind of high-efficiency antioxidant anti-acne handmade soap |
-
2018
- 2018-07-05 CN CN201810729464.4A patent/CN109846771A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1143442A (en) * | 1997-07-25 | 1999-02-16 | Lotte Co Ltd | Legionella bacteria resistant composition |
| CN105687032A (en) * | 2016-02-03 | 2016-06-22 | 湖南朗林生物制品有限公司 | Natural composition for improving health condition of skin |
| CN105833187A (en) * | 2016-05-14 | 2016-08-10 | 广东轻工职业技术学院 | Botanical medicine composition with acne removing effect and application |
| CN107595690A (en) * | 2017-09-01 | 2018-01-19 | 杨仁荷 | Anti-acne essence and preparation method thereof |
| CN107753341A (en) * | 2017-10-31 | 2018-03-06 | 广州赛莱拉干细胞科技股份有限公司 | A kind of moisturizing is releived skin care item and preparation method thereof |
| CN107789253A (en) * | 2017-10-31 | 2018-03-13 | 广州赛莱拉干细胞科技股份有限公司 | A kind of anti-acne moisturizing skin care item and preparation method thereof |
| CN107898681A (en) * | 2017-11-17 | 2018-04-13 | 珠海姗拉娜化妆品有限公司 | A kind of Novel acne treatment naturally extracts composition, acne eliminating cream and preparation method thereof |
| CN107937176A (en) * | 2017-11-30 | 2018-04-20 | 宁波秋日小城智能科技有限公司 | A kind of high-efficiency antioxidant anti-acne handmade soap |
| CN107865803A (en) * | 2017-12-18 | 2018-04-03 | 佛山市汇汾化妆品科技有限公司 | One kind preventing and treating acne composition |
Non-Patent Citations (2)
| Title |
|---|
| 陈明岭等: "《皮肤病常用中药药理及临床 第2版》", 31 October 2017, 中国科学技术出版社 * |
| 黄芝蓉等: "《家用食物功能手册》", 30 April 2009, 中国中医药出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110522687A (en) * | 2019-08-22 | 2019-12-03 | 广州市茗妍化妆品有限公司 | A kind of anti-acne shin moisturizer and preparation method thereof |
| CN112675087A (en) * | 2020-12-31 | 2021-04-20 | 肇庆迪彩日化科技有限公司 | Plant antibacterial and bacteriostatic scalp care composition and preparation method and application thereof |
| CN112870131A (en) * | 2021-03-31 | 2021-06-01 | 深圳市萱嘉生物科技有限公司 | Traditional Chinese medicine extract composition with acne removing effect and preparation method thereof |
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