KR102434748B1 - Method for Manufacturing Cosmetic composition for Moisturizing Cream containing Houttuynia Cordata Extract - Google Patents

Method for Manufacturing Cosmetic composition for Moisturizing Cream containing Houttuynia Cordata Extract Download PDF

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KR102434748B1
KR102434748B1 KR1020220066744A KR20220066744A KR102434748B1 KR 102434748 B1 KR102434748 B1 KR 102434748B1 KR 1020220066744 A KR1020220066744 A KR 1020220066744A KR 20220066744 A KR20220066744 A KR 20220066744A KR 102434748 B1 KR102434748 B1 KR 102434748B1
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여지은
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여지은
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/606Nucleosides; Nucleotides; Nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24Thermal properties
    • A61K2800/244Endothermic; Cooling; Cooling sensation

Abstract

The present invention relates to a cosmetic composition for a moisture cream containing an extract of Houttuynia cordata. The cosmetic composition includes: 50 parts by weight of a Houttuynia cordata extract; 50 parts by weight of a green tea extract; 6 parts by weight of hydrolyzed collagen; 60 parts by weight of panthenol; 20 parts by weight of pajama oil; 15 parts by weight of a Scutellaria baicalensis Georgi extract; 20 parts by weight of ceramide NP; 20 parts by weight of a candle bush leaf extract; 10 parts by weight of a Hamamelis virginiana extract; 10 parts by weight of arbutin; 10 parts by weight of adenosine; and 10 parts by weight of hyaluronic acid. The Houttuynia cordata extract and green tea extract are first mixed with hydrolyzed collagen, then ultrasonicated for 2 to 3 hours, and then the remaining ingredients except for the Houttuynia cordata extract and green tea extract are mixed. Even when stored for a long time, the cosmetic composition has excellent skin care and improvement effects.

Description

어성초 추출물을 포함하는 수분크림용용 화장료 조성물 제조방법{Method for Manufacturing Cosmetic composition for Moisturizing Cream containing Houttuynia Cordata Extract}Method for Manufacturing Cosmetic composition for Moisturizing Cream containing Houttuynia Cordata Extract

본 발명은 어성초 추출물을 포함하는 수분크림용 화장료 조성물에 관한 것으로, 보다 상세하게는 피부의 온도를 감소시키고 피부 수분을 유지시키면서 피부를 진정시키는 효과가 있으며 장기간 보관이 용이한 어성초 추출물을 포함하는 수분크림용 화장료 조성물에 관한 것이다. The present invention relates to a cosmetic composition for a moisture cream containing eoseongcho extract, and more particularly, to reduce the skin temperature and maintain skin moisture while calming the skin, and to a moisture containing eoseongcho extract that is easy to store for a long period of time It relates to a cosmetic composition for cream.

피부는 신체 중 가장 큰 기관으로서 물리적인 찰과상으로부터 보호하고, 몸 안에 가지고 있는 물의 손실을 막아 주며, 태양으로부터 나오는 해로운 자외선으로부터 보호해주고, 몸의 체온을 조절해주는데 매우 중요한 역할을 담당하고 있다. 피부는 외부 환경에 직접적으로 노출되는 부위로서, 과도한 자외선이나 오염 물질 등에 노출되면 홍반, 부종, 뾰루지, 따끔거림, 가려움 등의 피부 자극 및 염증 반응이 유발된다. 이러한 원인들에 의해 생성된 피부 트러블 은 미관상 문제가 될 뿐만 아니라, 염증 반응 과정에서 생성되는 물질들이 부수적으로 피부의 색소 침착을 일으 키고, 피부 탄력 섬유의 붕괴를 촉진시켜 피부 주름의 증가에까지 영향을 미치는 것으로 알려져 있다. 피부를 보호하고 미화 청결을 위해 사용되는 피부 외용 제품들에 있어서, 계면활성제, 방부제, 향료, 자외선 차단제, 기능성 원료 등의 사용이 불가피하지만, 이들 성분들은 피부에 여러 가지 부작용을 발생시키고 있다. 특히 미백, 주름 개선, 피부 진정 등을 목적으로 하는 기능성 제품에 함유되는 성분들이 피부트러블을 일으키는 주된 원인으로 작용하기도 한다. 이에 따라, 최근 소비자의 지향은 자연 친화적, 저자극성의 화장품을 선호하는 추세이며, 외부 환경 및 자극 유 발 물질로부터 민감성 피부를 보호하고 노화를 예방하고 최소화시킬 수 있는 피부 진정 및 피부 자극 완화용 물질에 대한 관심이 높아지고 있다. 최근에는 천연물에서 추출하고 분리한 물질들이 피부에 자극이 적고, 수렴작용, 항균 작용과 같은 기타의 약리작용을 가지고 있다는 사실이 널리 알려짐에 따라, 천연물을 이용하여 화장품 조성물을 제조하고자 하는 다양한 시도가 이루어지고 있다. As the largest organ in the body, the skin plays a very important role in protecting it from physical abrasions, preventing the loss of water in the body, protecting it from harmful ultraviolet rays from the sun, and regulating the body temperature. The skin is a part directly exposed to the external environment, and when exposed to excessive ultraviolet rays or pollutants, skin irritation and inflammatory reactions such as erythema, edema, pimples, tingling, and itching are induced. Skin troubles generated by these causes are not only aesthetically problematic, but substances generated in the inflammatory reaction process incidentally cause skin pigmentation and promote the breakdown of skin elastic fibers, which also affects the increase in skin wrinkles. known to affect In external skin products used to protect skin and beautify and clean, the use of surfactants, preservatives, fragrances, sunscreens, functional raw materials, etc. is inevitable, but these ingredients cause various side effects to the skin. In particular, ingredients contained in functional products for the purpose of whitening, wrinkle improvement, and skin soothing are also the main causes of skin troubles. Accordingly, the recent trend of consumers is to prefer nature-friendly and hypoallergenic cosmetics, and a substance for soothing and alleviating skin irritation that can protect sensitive skin from external environments and irritants and prevent and minimize aging. There is growing interest in Recently, as it is widely known that substances extracted and separated from natural products have less irritation to the skin and other pharmacological actions such as astringent and antibacterial actions, various attempts to prepare cosmetic compositions using natural products have been made. is being done

그리고, 세안 후에는 피부 정돈, 영양 및 수분 공급 등을 위하여 액상의 기초 화장품을 바르게 된다. 이러한 액상 기초 화장품에는 이른바 토너, 스킨, 로션, 에센스 등이 있는데 이런 제품을 바를 때에는 손에 있을 수 있는 세균 및 더러움이 얼굴에 묻지 않도록 따로 화장솜에 액상 화장품을 적용해 바르기도 한다.And, after washing the face, liquid basic cosmetics are applied for skin preparation, nutrition, and moisture supply. These liquid basic cosmetics include so-called toners, skins, lotions, and essences.

이 경우, 피부의 수분 유지, 진정 등의 효과와 함께 장기간 보관 시에도 안전하게 사용할 수 있는 화장료 개발이 필요하다. In this case, it is necessary to develop a cosmetic that can be safely used even when stored for a long time with effects such as moisture retention and soothing of the skin.

한편 피부 보습이나 관리를 위한 화장료 성분으로 어성초가 사용되고 있다. 어성초는 삼백초과에 속하는 다년생 초본으로서 학명은 Houttuynia Cordata이고, 중약대사전(상해과학기술출판사)에 따르면 약모밀, 십약 등의 다른 이름이 있다. 어성초는 잎, 줄기, 뿌리 전체에 유효성분이 함유되어 있으며 특유의 독특한 냄새를 포함한 생리활성물질들이 신진대사를 도와 혈액을 맑게 하고 신장기능을 촉진시키며, 염증 증상과 체내 독소를 배설하는 등의 기능이 있어서 중국, 일본 등에서 민간약으로 널리 이용되어 왔다. 한방에서 어성초는 고혈압, 변비증, 당뇨병, 해열, 종기, 해독, 관절염, 염증성 질환과 피부질환에 이용되고 있다. 대한민국 공개 특허 제10-2004-0007404호에는 어성초와 복분자의 혼합추출물을 유효성분으로 함유하는 알레르기 질환의 예방 및 치료용 조성물이 개시된 바 있다On the other hand, Eoseongcho is used as a cosmetic ingredient for skin moisturizing or management. Eoseongcho is a perennial herb belonging to the family Trifoliumaceae, and its scientific name is Houttuynia Cordata, and according to the Dictionary of Traditional Chinese Medicine (Shanghai Science and Technology Publishing Company), there are other names such as Yakmomil and Sipyak. Eoseongcho contains active ingredients in the entire leaf, stem, and root, and physiologically active substances including a unique odor help metabolism to purify blood, promote kidney function, and have functions such as inflammatory symptoms and excretion of toxins from the body. It has been widely used as a folk medicine in China and Japan. In oriental medicine, Eoseongcho is used for high blood pressure, constipation, diabetes, fever, boils, detoxification, arthritis, inflammatory diseases and skin diseases. Korean Patent Laid-Open Patent No. 10-2004-00007404 discloses a composition for preventing and treating allergic diseases containing a mixed extract of eoseongcho and bokbunja as an active ingredient.

하지만, 어성초가 실제 화장료의 에멀젼 형태로 사용되는 경우, 유화 상태에서 장기간 보관시 변성되는 등의 문제가 있으며, 보습 등의 효과가 오랫동안 유지되지 않으며, 공기 중으로 쉽게 날라가는 문제가 있다. However, when Eoseongcho is actually used in the form of an emulsion of a cosmetic, there is a problem such as being denatured when stored for a long time in an emulsified state, the effect of moisturizing is not maintained for a long time, and there is a problem that it is easily blown into the air.

등록특허 10-2349786 : 주름 개선 및 미백용 화장료 조성물Registered Patent 10-2349786 : Cosmetic composition for wrinkle improvement and whitening

따라서, 본 발명이 해결하기 위한 과제는 어성초 등을 유효성분으로 사용하며 피부 온도 감소, 피부 보습, 피부 진정 효과 등을 극대화시키며 장기간 보관시에도 우수한 피부관리, 개선 효과를 갖는 수분크림용 화장표 조성물을 제공하는 것이다. Therefore, the problem to be solved by the present invention is a cosmetic composition for a moisture cream that uses eosin-chief as an active ingredient, maximizes skin temperature reduction, skin moisturizing, skin soothing effect, etc., and has excellent skin care and improvement effects even when stored for a long period of time is to provide

본 발명은, 어성초 추출물을 포함하는 수분크림용 화장료 조성물로서, 어성초추출물 50중량부; 녹차추출물 50 중량부; 하이드롤라이즈드콜라겐 6중량부; 판테놀 60중량부; 파자마오일 20중량부; 황금추출물 15중량부; 세라마이드엔피 20중량부; 캔들부쉬잎 추출물 20 중량부; 및 버지니아풍년화잎 추출물 10 중량부; 알부틴 10중량부; 아데노신 10중량부; 히알루로닉애씨드 10중량부로 이루어진 것을 특징으로 하는 수분크림용 화장료 조성물을 제공한다.The present invention, as a cosmetic composition for a moisture cream comprising an eoseongcho extract, 50 parts by weight of eoseongcho extract; 50 parts by weight of green tea extract; 6 parts by weight of hydrolyzed collagen; 60 parts by weight of panthenol; 20 parts by weight of pajama oil; 15 parts by weight of golden extract; Ceramide NP 20 parts by weight; 20 parts by weight of candlebush leaf extract; and 10 parts by weight of an extract of Virginia fern leaf extract; Arbutin 10 parts by weight; 10 parts by weight of adenosine; It provides a cosmetic composition for a moisture cream, characterized in that it consists of 10 parts by weight of hyaluronic acid.

상기 어성초추출물과 녹차추출물은 하이드롤라이즈드콜라겐에 먼저 혼합된 후, 2 내지 3시간 동안 초음파 처리되며, 이후 상기 어성초추출물과 녹차추출물을 제외한 나머지 성분이 혼합된다.The eoseongcho extract and green tea extract are first mixed with hydrolyzed collagen, and then sonicated for 2 to 3 hours, and then the remaining ingredients except for the eoseongcho extract and green tea extract are mixed.

또한, 본 발명은 상기 어성초추출물과 녹차추출물을 하이드롤라이즈드 콜라겐에 혼합하는 단계; 상기 혼합된 하이드롤라이즈드콜라겐을 섭씨 50 내지 70도의 온도에서 2시간 동안 초음파 처리하는 단계; 및 상기 판테놀, 파자마오일, 황금추출물, 세라마이드엔피, 캔들부쉬잎 추출물, 버지니아풍년화잎 추출물, 알부틴, 아데노신 및 히알루로닉애씨드를 상기 초음파처리된 용액에 혼합하는 단계;를 포함하는 것을 특징으로 하는 수분크림용 화장료 조성물 제조방법을 제공한다.In addition, the present invention comprises the steps of mixing the eoseongcho extract and green tea extract with hydrolyzed collagen; Sonicating the mixed hydrolyzed collagen at a temperature of 50 to 70 degrees Celsius for 2 hours; and mixing the panthenol, pajama oil, golden extract, ceramide NP, candlebush leaf extract, Virginia fern leaf extract, arbutin, adenosine and hyaluronic acid into the sonicated solution; Moisture comprising a; A method for preparing a cosmetic composition for a cream is provided.

본 발명에 따른 조성물은 피부 온도 감소, 피부 보습, 피부 진정 효과 등의 개선 효과를 장기간 유지할 수 있다.The composition according to the present invention can maintain improvement effects such as skin temperature reduction, skin moisturizing, and skin soothing effect for a long period of time.

도 1은 본 발명의 일 실시예에 따른 화장료 제조방법의 단계도이다. 1 is a step diagram of a method for manufacturing a cosmetic according to an embodiment of the present invention.

이하, 첨부한 도면을 참고로 하여 본 발명의 바람직한 실시예에 대하여 상세히 설명하면 다음과 같다.Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

본 발명을 상세하게 설명하기 전에, 본 명세서에서 사용된 용어나 단어는 통상적이거나 사전적인 의미로 무조건 한정하여 해석되어서는 아니 되며, 본 발명의 발명자가 자신의 발명을 가장 최선의 방법으로 설명하기 위해서 각종 용어의 개념을 적절하게 정의하여 사용할 수 있다.Before describing the present invention in detail, the terms or words used herein should not be construed as being unconditionally limited to their ordinary or dictionary meanings, and in order for the inventor of the present invention to describe his invention in the best way Concepts of various terms can be appropriately defined and used.

더 나아가 이들 용어나 단어는 본 발명의 기술적 사상에 부합하는 의미와 개념으로 해석되어야 함을 알아야 한다.Furthermore, it should be understood that these terms or words should be interpreted as meanings and concepts consistent with the technical spirit of the present invention.

즉, 본 명세서에서 사용된 용어는 본 발명의 바람직한 실시예를 설명하기 위해서 사용되는 것일 뿐이고, 본 발명의 내용을 구체적으로 한정하려는 의도로 사용된 것이 아니다. 이들 용어는 본 발명의 여러 가지 가능성을 고려하여 정의된 용어임을 알아야 한다. 또한, 본 명세서에 있어서, 단수의 표현은 문맥상 명확하게 다른 의미로 지시하지 않는 이상, 복수의 표현을 포함할 수 있다.That is, the terms used herein are only used to describe preferred embodiments of the present invention, and are not intended to specifically limit the content of the present invention. It should be understood that these terms are defined in consideration of various possibilities of the present invention. Also, in the present specification, a singular expression may include a plural expression unless the context clearly indicates otherwise.

본 명세서의 전체에 걸쳐서 어떤 구성 요소가 다른 구성 요소를 "포함"한다고 기재하는 경우에는, 특별히 반대되는 의미의 기재가 없는 한 임의의 다른 구성 요소를 제외하는 것이 아니라 임의의 다른 구성 요소를 더 포함할 수도 있다는 것을 의미할 수 있다.In the case where it is stated throughout this specification that a component "includes" another component, it does not exclude any other component, but further includes any other component unless otherwise indicated. It could mean that you can.

본 발명은 상술한 문제를 해결하기 위하여, 어성초 추출물과 녹차 추출물을 포함하는 화장료 조성물을 제공한다. 특히 본 발명은 어성초와 녹차추출물을 하이드롤라이즈드콜라겐에 혼합한 후, 이를 초음파 처리하여 핵심 추출물 성분을 콜라겐에 먼저 결합시킨다. 하이드롤라이즈드콜라겐은 콜라겐의 가수분해를 통해 생긴 작은 펩타이드의 혼합물로서, 특히 어성초 추출물의 유효성분인 하이르록실기를 이펩타이드에 먼저 결합시킴으로써 증발 등을 막아 유효성분의 효과를 오래 유지시킬 수 있다. The present invention provides a cosmetic composition comprising eoseongcho extract and green tea extract in order to solve the above problems. In particular, in the present invention, after mixing eoseongcho and green tea extract in hydrolyzed collagen, it is sonicated to bind the core extract component to collagen first. Hydrolyzed collagen is a mixture of small peptides generated through the hydrolysis of collagen. In particular, by first binding the hydroxyl group, an active ingredient of the Echo extract, to this peptide, evaporation, etc., can be prevented and the effect of the active ingredient can be maintained for a long time. .

본 발명은 어성초 추출물을 포함하는 수분크림용 화장료 조성물로서, 상기 어성초추출물 50중량부; 녹차추출물 50 중량부; 하이드롤라이즈드콜라겐 6중량부; 판테놀 60중량부; 파자마오일 20중량부; 황금추출물 15중량부; 세라마이드엔피 20중량부; 캔들부쉬잎 추출물 20 중량부; 및 버지니아풍년화잎 추출물 10 중량부; 알부틴 10중량부; 아데노신 10중량부; 히알루로닉애씨드 10중량부로 이루어진다.The present invention is a cosmetic composition for a moisture cream comprising an eoseongcho extract, 50 parts by weight of the eoseongcho extract; 50 parts by weight of green tea extract; 6 parts by weight of hydrolyzed collagen; 60 parts by weight of panthenol; 20 parts by weight of pajama oil; 15 parts by weight of golden extract; Ceramide NP 20 parts by weight; 20 parts by weight of candlebush leaf extract; and 10 parts by weight of an extract of Virginia fern leaf extract; Arbutin 10 parts by weight; 10 parts by weight of adenosine; It consists of 10 parts by weight of hyaluronic acid.

본 발명에 따른 상기 추출물은 당업계에 공지된 추출 및 분리하는 방법을 사용하여 추출물을 분리 및 수득한 것을 사용할 수 있으며, 본 발명에서 정의된 추출물은 적절한 용매를 이용하여 상기의 방법으로 준비된 유효성분 원료를 그대로 또는 분쇄하여 추출할 수 있다. 이때 추출물을 수득하기 위해 사용할 수 있는 적절한 용매로는 당업계에서 허용되는 용매라면 어느 것을 사용해도 무방하며, 물 또는 유기용매를 사용할 수 있다. 예를 들어, 정제수, 메탄올(methanol), 에탄올(ethanol), 프로판올(propanol), 이소프로판올(isopropanol), 부탄올(butanol) 등을 포함하는 탄소수 1 내지 4의 알코올, 아세톤(acetone), 에테르(ether), 벤젠(benzene), 클로로포름(chloroform), 에틸아세테이트(ethyl acetate), 메틸렌클로라이드(methylene chloride), 헥산(hexane) 및 시클로헥산(cyclohexane) 등의 각종 용매를 단독으로 혹은 혼합하여 사용할 수 있으나, 이에 제한되지는 않는다.The extract according to the present invention may be obtained by separating and obtaining the extract using a method known in the art for extraction and separation, and the extract defined in the present invention is an active ingredient prepared by the above method using an appropriate solvent. The raw material may be extracted as it is or by grinding. In this case, as a suitable solvent that can be used to obtain the extract, any solvent acceptable in the art may be used, and water or an organic solvent may be used. For example, purified water, methanol (methanol), ethanol (ethanol), propanol (propanol), isopropanol (isopropanol), alcohols having 1 to 4 carbon atoms including butanol (butanol), acetone (acetone), ether (ether) , benzene (benzene), chloroform (chloroform), ethyl acetate (ethyl acetate), methylene chloride (methylene chloride), hexane (hexane) and various solvents such as cyclohexane (cyclohexane) can be used alone or in combination, but Not limited.

추출 방법으로는 열수추출법, 냉침추출법, 환류냉각추출법, 용매추출법, 수증기증류법, 초음파추출법, 용출법, 압착법 등의 방법 중 어느 하나를 선택하여 사용할 수 있다. 또한, 목적하는 추출물은 추가로 통상의 분획 공정을 수행할 수도 있으며, 통상의 정제 방법을 이용하여 정제될 수도 있다. 본 발명의 추출물의 제조방법에는 제한이 없으며, 공지되어 있는 어떠한 방법도 이용될 수 있다As the extraction method, any one of methods such as hot water extraction, cold extraction, reflux cooling extraction, solvent extraction, steam distillation, ultrasonic extraction, elution, and compression may be selected and used. In addition, the desired extract may be further subjected to a conventional fractionation process, and may be purified using a conventional purification method. There is no limitation on the method for preparing the extract of the present invention, and any known method may be used.

여기에서 바람직하게는 상기 어성초추출물과 녹차추출물은 하이드롤라이즈드콜라겐에 먼저 혼합된 후, 2 내지 3시간 동안 초음파 처리되며, 이후 상기 어성초추출물과 녹차추출물을 제외한 나머지 성분이 혼합된다. Here, preferably, the eoseongcho extract and green tea extract are first mixed with hydrolyzed collagen, and then sonicated for 2 to 3 hours, and then the rest of the components except for the eoseongcho extract and green tea extract are mixed.

본 발명에서 상기 어성초 추출물은 항염, 아토피, 여드름에 효과가 있으며, 녹차추출물은 피부를 진정시키고 쿨링하는 효과가 있다. 또한, 본 발명의 판테놀은 피부 수분을 유지하고 피부발진을 예방하며, 파자마오일은 항염 및 보습의 보습의 효과가 있다. 그리고, 본 발명의 황금추출물은 항산화, 피부보호, 피부진정, 항염 및 항균의 효과가 발휘되며, 세라마이드엔피는 피부 보습을 강화하고 피부 장벽을 강화하는 효과가 있다. 그리고, 캔들부쉬잎 추출물은 피부 컨디셔닝과 보습의 효과가 있고, 버지니아풍년화잎 추출물은 피부트러블을 완화하고 모공탄력을 증가시키는 효능이 있다. 또한, 히알루로닉애씨드는 피부 보습에 효과가 있다. 그리고, 본 발명의 기능성 원료인 알부틴은 미백의 효과가 있고, 아데노신은 피부 주름 개선의 효과가 있다. In the present invention, the eoseongcho extract is effective in anti-inflammatory, atopy and acne, and green tea extract has an effect of soothing and cooling the skin. In addition, the panthenol of the present invention maintains skin moisture and prevents skin rashes, and pajama oil has anti-inflammatory and moisturizing effects. And, the golden extract of the present invention exhibits antioxidant, skin protection, skin soothing, anti-inflammatory and antibacterial effects, and ceramide NP enhances skin moisture and strengthens the skin barrier. In addition, the Candlebush leaf extract has the effect of conditioning and moisturizing the skin, and the Virginia Peony leaf extract has the effect of alleviating skin troubles and increasing the elasticity of the pores. In addition, hyaluronic acid is effective in moisturizing the skin. And, arbutin, which is a functional raw material of the present invention, has an effect of whitening, and adenosine has an effect of improving skin wrinkles.

본 발명의 실시예에 따른 상기 어성초 추출물은 항염, 아토피, 여드름 개선 효과를 가지며, 녹차 추출물은 피부진정과, 쿨링효과를 갖는다. 즉, 본 발명은 이러한 핵심 성분을 먼저 하이드롤라이즈드콜라겐에 혼합시켜 화장료의 효능 안정성을 향상시키며, 이후 항산화, 피부진정, 피부 보습, 주름 개선, 미백 등의 효능을 가지는 판테놀, 파자마오일, 황금추출물, 세라마이드엔피, 캔들부쉬잎 추출물, 버지니아풍년화잎 추출물, 알부틴, 아데노신, 히알루로닉애씨드를 상기 배합비율로 혼합한다.According to an embodiment of the present invention, the extract of eosinthiasis has anti-inflammatory, atopy, and acne improving effects, and the green tea extract has skin soothing and cooling effects. That is, the present invention improves the efficacy and stability of cosmetics by first mixing these key ingredients with hydrolyzed collagen, and then panthenol, pajama oil, golden Extract, ceramide NP, Candlebush leaf extract, Virginia lotus leaf extract, arbutin, adenosine, and hyaluronic acid are mixed in the above mixing ratio.

본 발명에서 상술한 추출물은 열수추출 등의 공지된 방법으로 추출될 수 있으며, 본 발명의 범위는 추출 방법 등에 의하여 한정되지 않는다. The extract described above in the present invention may be extracted by a known method such as hot water extraction, and the scope of the present invention is not limited by the extraction method.

실시예Example

본 발명의 일 실시예에 따른 화장료 제조방법의 단계를 보다 상세히 설명하면 다음과 같다. The steps of the cosmetic preparation method according to an embodiment of the present invention will be described in more detail as follows.

어성초추출물 100g과 녹차추출물 100g을 하이드롤라이즈드콜라겐 12g과 혼합하였다. 이때 온도는 섭씨 60도로 하여 초음파 처리를 통하여 혼합하였다. 그리고, 판테놀 120g, 파자마오일 40g, 황금추출물 30g, 세라마이드엔피 40g, 캔들부쉬잎 추출물 40g, 버지니아풍년화잎 추출물 20g, 알부틴 20g, 아데노신 20g, 히알루로닉애씨드 20g을 혼합하였다. 100 g of Eoseongcho extract and 100 g of green tea extract were mixed with 12 g of hydrolyzed collagen. At this time, the temperature was set to 60 degrees Celsius and the mixture was mixed through ultrasonication. And, panthenol 120g, pajama oil 40g, golden extract 30g, ceramide NP 40g, candlebush leaf extract 40g, Virginia fern leaf extract 20g, arbutin 20g, adenosine 20g, hyaluronic acid 20g was mixed.

비교예comparative example

비교예에서는 어성초추출물, 녹차추출물, 판테놀을 나머지 모든 성분과 함께 혼합하여 화장료 조성물을 제조하였다. In the comparative example, a cosmetic composition was prepared by mixing eoseongcho extract, green tea extract, and panthenol with all the remaining ingredients.

실험예 1Experimental Example 1

DPPH 라디칼 소거능 DPPH radical scavenging ability

어성초가 가지는 유효한 효과 중 하나인 노화억제 효과를 확인하기 위하여 1,1-diphenyl-2-picrylhydrazyl(DPPH, Sigma, USA)라디칼소거능을 측정하였다. 실시예 및 비교예의 시료를 MeOH로 녹여500 ㎕를 1.5 ㎖ tube에 넣고 0.3 mM DPPH 500 ㎕를 넣어 총양이 1 ㎖가 되도록 하였다. 실온에서 30분간 반응시킨 후 ELISA reader(Bio-Tek, USA)로 517 nm 파장에서 흡광도를 측정하였다. DPPH 라디칼 소거능은 시료의 첨가구와 무첨가구사이의 흡광도의 차이를 백분율로 나타내었다. 하기 표 1은 초기 1일 및 상온 보관후 14일 경과한 후의 실험결과이다. 1,1-diphenyl-2-picrylhydrazyl (DPPH, Sigma, USA) radical scavenging ability was measured in order to confirm the anti-aging effect, which is one of the effective effects of Eoseongcho. The samples of Examples and Comparative Examples were dissolved in MeOH, 500 μl was put into a 1.5 ml tube, and 500 μl of 0.3 mM DPPH was added so that the total amount was 1 ml. After reacting at room temperature for 30 minutes, absorbance was measured at 517 nm wavelength with an ELISA reader (Bio-Tek, USA). The DPPH radical scavenging ability was expressed as a percentage of the difference in absorbance between the addition group and the non-additive group of the sample. Table 1 below shows the experimental results after the initial 1 day and 14 days after storage at room temperature.

1일 1 day 14일14 days 실시예 Example 53.8%53.8% 50.6%50.6% 비교예comparative example 49.5%49.5% 31.4%31.4%

위 결과를 참조하면, 펩타이드와 어성초 성분을 먼저 결합시키지 않은 비교예의 경우 14일이 경과한 경우 어성초 등에 의한 라디칼 소거능이 급격하게 떨어지는 것을 알 수 있다. 이것은 어성초 추출물의 유효성분의 기능기가 비교적 단분자인 펩타이드와 다량으로 결합하게 됨으로써 얻는 효과라 판단된다. Referring to the above results, it can be seen that in the case of the comparative example in which the peptide and eoseongcho component were not first combined, the radical scavenging ability by eoseongcho, etc. rapidly decreased when 14 days had elapsed. This is judged to be an effect obtained by binding a large amount of the functional group of the active ingredient of the Ewoongcho extract to the relatively monomolecular peptide.

실험예 2Experimental Example 2

피부보습 효과 실험Skin moisturizing effect test

알레르기성 질환이나 아토피 피부염등질환의 병력이 없는 건강한 성인 남녀 5명을 대상으로 하여 도포 후 2일 경과 후 피부보습 효과를 측정하였다. 이때 수분 함량을 피부 정전부하용량 계측법(skin capacitance measurement)으로 측정하는 장비인 피부 수분 량 측정기(Corneometer CM 825)를 이용하여 피부의 수분 함량을 측정하였다. The skin moisturizing effect was measured 2 days after application in 5 healthy adult males and females without a history of allergic diseases or atopic dermatitis. At this time, the moisture content of the skin was measured using a skin moisture meter (Corneometer CM 825), which is a device for measuring the moisture content by skin capacitance measurement.

1일 1 day 2일2 days 실시예 Example 90.5%90.5% 88.388.3 비교예comparative example 85.5%85.5% 60.3%60.3%

이상의 결과는 본 발명에 따른 조성물은 항노화, 피부보습 등의 피부개선 효과를 장기간 유지할 수 있음을 의미한다. The above results mean that the composition according to the present invention can maintain skin improvement effects such as anti-aging and skin moisturizing for a long time.

이상에서 본 발명의 바람직한 실시예에 대하여 상세하게 설명하였지만 본 발명의 권리범위는 이에 한정되는 것은 아니고 다음의 청구범위에서 정의하고 있는 본 발명의 기본 개념을 이용한 당업자의 여러 변형 및 개량 형태 또한 본 발명의 권리범위에 속하는 것이다.Although preferred embodiments of the present invention have been described in detail above, the scope of the present invention is not limited thereto, and various modifications and improvements by those skilled in the art using the basic concept of the present invention as defined in the following claims are also provided. is within the scope of the

Claims (3)

어성초추출물 50중량부; 녹차추출물 50 중량부; 하이드롤라이즈드콜라겐 6중량부; 판테놀 60중량부; 파자마오일 20중량부; 황금추출물 15중량부; 세라마이드엔피 20중량부; 캔들부쉬잎 추출물 20 중량부; 및 버지니아풍년화잎 추출물 10 중량부; 알부틴 10중량부; 아데노신 10중량부; 히알루로닉애씨드 10중량부로 이루어진 수분크림용 화장료 조성물 제조방법으로서,
상기 어성초추출물과 녹차추출물을 하이드롤라이즈드콜라겐에 혼합하는 단계;
상기 혼합된 하이드롤라이즈드콜라겐을 섭씨 50 내지 70도의 온도에서 2시간 동안 초음파 처리하는 단계; 및
상기 판테놀, 파자마오일, 황금추출물, 세라마이드엔피, 캔들부쉬잎 추출물, 버지니아풍년화잎 추출물, 알부틴, 아데노신 및 히알루로닉애씨드를 상기 초음파처리된 용액에 혼합하는 단계;를 포함하는 것을 특징으로 하는 수분크림용 화장료 조성물 제조방법.
50 parts by weight of eoseongcho extract; 50 parts by weight of green tea extract; 6 parts by weight of hydrolyzed collagen; 60 parts by weight of panthenol; 20 parts by weight of pajama oil; 15 parts by weight of golden extract; Ceramide NP 20 parts by weight; 20 parts by weight of candlebush leaf extract; and 10 parts by weight of Virginia Peony Leaf extract; Arbutin 10 parts by weight; 10 parts by weight of adenosine; As a method of manufacturing a cosmetic composition for a moisture cream consisting of 10 parts by weight of hyaluronic acid,
mixing the eoseongcho extract and green tea extract with hydrolyzed collagen;
Sonicating the mixed hydrolyzed collagen at a temperature of 50 to 70 degrees Celsius for 2 hours; and
The step of mixing the panthenol, pajama oil, golden extract, ceramide NP, candlebush leaf extract, virginia leaf extract, arbutin, adenosine and hyaluronic acid into the sonicated solution; moisture cream comprising a; A method for preparing a cosmetic composition for use.
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