CN109718185A - One kind is releived antianaphylactic herbal composite - Google Patents
One kind is releived antianaphylactic herbal composite Download PDFInfo
- Publication number
- CN109718185A CN109718185A CN201910182961.1A CN201910182961A CN109718185A CN 109718185 A CN109718185 A CN 109718185A CN 201910182961 A CN201910182961 A CN 201910182961A CN 109718185 A CN109718185 A CN 109718185A
- Authority
- CN
- China
- Prior art keywords
- antianaphylactic
- radix
- extraction
- carries out
- herbal composite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002804 anti-anaphylactic effect Effects 0.000 title claims abstract description 21
- 239000002131 composite material Substances 0.000 title claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 210000000582 semen Anatomy 0.000 claims abstract description 8
- 241001645380 Bassia scoparia Species 0.000 claims abstract description 7
- 240000005001 Paeonia suffruticosa Species 0.000 claims abstract description 7
- 235000003889 Paeonia suffruticosa Nutrition 0.000 claims abstract description 7
- 244000143590 Salvia chinensis Species 0.000 claims abstract description 7
- 235000007154 Salvia chinensis Nutrition 0.000 claims abstract description 7
- 235000005794 Salvia japonica Nutrition 0.000 claims abstract description 7
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 7
- 230000001815 facial effect Effects 0.000 claims abstract description 7
- 238000002360 preparation method Methods 0.000 claims abstract description 7
- 244000157790 Buglossoides arvense Species 0.000 claims abstract description 6
- 235000004256 Buglossoides arvense Nutrition 0.000 claims abstract description 6
- 244000234609 Portulaca oleracea Species 0.000 claims abstract description 6
- 235000001855 Portulaca oleracea Nutrition 0.000 claims abstract description 6
- 239000006071 cream Substances 0.000 claims abstract description 4
- 239000000654 additive Substances 0.000 claims abstract description 3
- 230000000996 additive effect Effects 0.000 claims abstract description 3
- 239000006210 lotion Substances 0.000 claims abstract description 3
- 238000004140 cleaning Methods 0.000 claims abstract 3
- 238000000605 extraction Methods 0.000 claims description 12
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 4
- 238000000926 separation method Methods 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 3
- 239000002904 solvent Substances 0.000 claims description 3
- 238000002137 ultrasound extraction Methods 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 2
- 238000007654 immersion Methods 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims description 2
- 238000004062 sedimentation Methods 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 abstract description 2
- 239000000490 cosmetic additive Substances 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 23
- 239000003814 drug Substances 0.000 description 17
- 230000000694 effects Effects 0.000 description 17
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 12
- 239000002537 cosmetic Substances 0.000 description 11
- 229940079593 drug Drugs 0.000 description 11
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 description 8
- 241000721047 Danaus plexippus Species 0.000 description 8
- 230000003110 anti-inflammatory effect Effects 0.000 description 7
- 241000411851 herbal medicine Species 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 230000002401 inhibitory effect Effects 0.000 description 6
- 201000004624 Dermatitis Diseases 0.000 description 5
- 206010020751 Hypersensitivity Diseases 0.000 description 5
- 230000003712 anti-aging effect Effects 0.000 description 5
- 150000003254 radicals Chemical class 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 238000011282 treatment Methods 0.000 description 5
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 4
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 4
- 229920002385 Sodium hyaluronate Polymers 0.000 description 4
- 208000026935 allergic disease Diseases 0.000 description 4
- 230000007815 allergy Effects 0.000 description 4
- 230000003266 anti-allergic effect Effects 0.000 description 4
- 239000003963 antioxidant agent Substances 0.000 description 4
- 230000003078 antioxidant effect Effects 0.000 description 4
- 229960003237 betaine Drugs 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 4
- SVTBMSDMJJWYQN-UHFFFAOYSA-N hexylene glycol Natural products CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 4
- 229940051250 hexylene glycol Drugs 0.000 description 4
- 230000003020 moisturizing effect Effects 0.000 description 4
- 229940010747 sodium hyaluronate Drugs 0.000 description 4
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 description 3
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 3
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 3
- 108060001084 Luciferase Proteins 0.000 description 3
- 239000005089 Luciferase Substances 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 210000001789 adipocyte Anatomy 0.000 description 3
- 230000000578 anorexic effect Effects 0.000 description 3
- 208000010668 atopic eczema Diseases 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 239000005556 hormone Substances 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 229940010454 licorice Drugs 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000035755 proliferation Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 239000004475 Arginine Substances 0.000 description 2
- 241000984231 Atractylodes chinensis Species 0.000 description 2
- VAVMMEMXCQCWCG-UHFFFAOYSA-N CN(C)CCS(O)(=O)=O.C=CC(N)=O.N Chemical compound CN(C)CCS(O)(=O)=O.C=CC(N)=O.N VAVMMEMXCQCWCG-UHFFFAOYSA-N 0.000 description 2
- 244000077995 Coix lacryma jobi Species 0.000 description 2
- 235000007354 Coix lacryma jobi Nutrition 0.000 description 2
- MKMCJLMBVKHUMS-UHFFFAOYSA-N Coixol Chemical compound COC1=CC=C2NC(=O)OC2=C1 MKMCJLMBVKHUMS-UHFFFAOYSA-N 0.000 description 2
- 206010012442 Dermatitis contact Diseases 0.000 description 2
- 206010015150 Erythema Diseases 0.000 description 2
- 240000004670 Glycyrrhiza echinata Species 0.000 description 2
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 2
- 240000007817 Olea europaea Species 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 201000004681 Psoriasis Diseases 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 2
- 229930013930 alkaloid Natural products 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 2
- 201000008937 atopic dermatitis Diseases 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 229960001631 carbomer Drugs 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 229940082500 cetostearyl alcohol Drugs 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 208000010247 contact dermatitis Diseases 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 229930182478 glucoside Natural products 0.000 description 2
- 150000008131 glucosides Chemical class 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 230000004089 microcirculation Effects 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 229940049964 oleate Drugs 0.000 description 2
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 2
- -1 oxygen radical Chemical class 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000005808 skin problem Effects 0.000 description 2
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 230000002087 whitening effect Effects 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- NEZONWMXZKDMKF-JTQLQIEISA-N Alkannin Chemical compound C1=CC(O)=C2C(=O)C([C@@H](O)CC=C(C)C)=CC(=O)C2=C1O NEZONWMXZKDMKF-JTQLQIEISA-N 0.000 description 1
- 239000004229 Alkannin Substances 0.000 description 1
- 244000061520 Angelica archangelica Species 0.000 description 1
- NBGBEUITCPENLJ-UHFFFAOYSA-N Bunazosin hydrochloride Chemical compound Cl.C1CN(C(=O)CCC)CCCN1C1=NC(N)=C(C=C(OC)C(OC)=C2)C2=N1 NBGBEUITCPENLJ-UHFFFAOYSA-N 0.000 description 1
- 102000005600 Cathepsins Human genes 0.000 description 1
- 108010084457 Cathepsins Proteins 0.000 description 1
- DPQCZNIGGNJGTD-UHFFFAOYSA-N Chloride-(??)-2-Methylpentanoic acid Natural products CCCCCCC=CCCCCCCCCCC(=O)OC(C)C(C)OC(=O)CCCCCCCC=CCCCCCC DPQCZNIGGNJGTD-UHFFFAOYSA-N 0.000 description 1
- DPQCZNIGGNJGTD-MVCBGFDASA-N Coixenolide Chemical compound CCCCCC\C=C\CCCCCCCCCC(=O)O[C@@H](C)[C@@H](C)OC(=O)CCCCCCC\C=C/CCCCCC DPQCZNIGGNJGTD-MVCBGFDASA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010012434 Dermatitis allergic Diseases 0.000 description 1
- 206010012438 Dermatitis atopic Diseases 0.000 description 1
- 235000002673 Dioscorea communis Nutrition 0.000 description 1
- 241000544230 Dioscorea communis Species 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 244000303040 Glycyrrhiza glabra Species 0.000 description 1
- 235000001287 Guettarda speciosa Nutrition 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000003351 Melanosis Diseases 0.000 description 1
- 206010033733 Papule Diseases 0.000 description 1
- 208000035753 Periorbital contusion Diseases 0.000 description 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 description 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 description 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- XBBAEVVIDHSGKC-UHFFFAOYSA-N [As].[Hg] Chemical compound [As].[Hg] XBBAEVVIDHSGKC-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- UNNKKUDWEASWDN-UHFFFAOYSA-N alkannin Natural products CC(=CCC(O)c1cc(O)c2C(=O)C=CC(=O)c2c1O)C UNNKKUDWEASWDN-UHFFFAOYSA-N 0.000 description 1
- 235000019232 alkannin Nutrition 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000000629 anti-dermatophyte Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 125000000332 coumarinyl group Chemical class O1C(=O)C(=CC2=CC=CC=C12)* 0.000 description 1
- 238000005138 cryopreservation Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 229960001340 histamine Drugs 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000005847 immunogenicity Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000011221 initial treatment Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000008099 melanin synthesis Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000002068 microbial inoculum Substances 0.000 description 1
- 210000000107 myocyte Anatomy 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000005502 peroxidation Methods 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 229940064064 purslane extract Drugs 0.000 description 1
- 238000007348 radical reaction Methods 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 210000000636 white adipocyte Anatomy 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
It releives antianaphylactic herbal composite the present invention provides one kind, it is the cosmetic additive agent being prepared by the raw material of following weight proportion: purslane 20-25%, radix scutellariae 10-13%, kuh-seng 10-20%, Asian puccoon 8-15%, root bark of tree peony 4-10%, Salvia japonica 10-20%, semen coicis 10-20%, fruit of summer cypress 4-10%, radix saposhnikoviae 2-8%, Radix Angelicae Sinensis 2-8%, rhizoma atractylodis 2-8%, Radix Glycyrrhizae 2-8%.It releives in antianaphylactic skin care item, including facial mask, water, essence, milky lotion, cream and cleaning product applied to preparation, additive amount 1-5%.
Description
Technical field
It releives antianaphylactic herbal composite the present invention relates to one kind, specially one kind is releived antianaphylactic Chinese herbal medicine group
Close method for preparing extractive and the application of object.
Background technique
The production and use of natural skin care product have had thousands of years history in China.It is received if in Shennong's Herbal
A variety of Chinese herbal medicine cosmetic formulations are recorded.The Compendium of Material Medica of Li Shizhen (1518-1593 A.D.) is even more to collect the great achievement of successive dynasties beauty prescription, for modern research and development
Reliable foundation is provided with exploitation natural cosmetics.
With the development and improvement of living standard of commodity economy, people are more and more common to the pursuit of beauty.Sense of loving to make up and wearing beautiful clothes,
It is owned by everyone.And most direct, the most effective commodity of this needs of people are able to satisfy, it is all kinds of cosmetics.Because various natural
It is cosmetics, nonirritant, to the skin fanout free region of people, so favoring by the majority of consumers.
People are common and the cosmetics overwhelming majority that uses is synthetic, in these chemically synthesized cosmetics,
General all different degrees of contain harmful substances, the toxic side effects of these substances such as lead mercury arsenic often cause allergy anti-to user
It answers.Serious pollution with environment in especially this several years, the skin of people are generally more fragile.Therefore, it is necessary to a kind of natural to relax
Slow antianaphylaxis components alleviate the skin problem of people.
Allergic reaction is the immunogenicity inflammatory reaction that skin generates certain substance, occurs to be also known as allergic effect on the person
Property contact dermatitis, by itch, erythema, papule, blister, fusion blister characterized by.Cosmetics improper use can cause skin mistake
Phenomena such as quick, itch, furfur, redness, red capillary, occurs.Preservative in cosmetic material, surfactant, kills at spices and essence
Microbial inoculum, pigment, has sun-screening agent, antioxidant etc. and can become sensibiligen preservative.
Chinese medicine compound prescription is mainly to be carried out according to the prescription theory of " monarch " and the principles of formulating prescriptions of " seven feelings compatibilities ".It closes
Yu Jun, the theory for minister, helping, making prescription, see Huangdi's Internal Classics earliest, and " Plain Questions to very to discuss greatly " is said: " main disease for monarch,
Help monarch is minister, and answer minister is to make." monarch drug in a prescription is to play the drug of primary treatment for main disease or main symptom.Ministerial drug connotation has two
It is a, first is that auxiliary monarch drug in a prescription reinforces the drug of the main disease for the treatment of or main symptom effect;It is mainly controlled second is that being risen for important simultaneous disease or accompanying symptoms
The drug for the treatment of effect.Adjutant i.e. cooperation monarch drug in a prescription, ministerial drug is to reinforce therapeutic effect, or directly treats the drug of secondary accompanying symptoms.Make medicine
For harmonizing drug, the i.e. drug with all medicine effects in reconciliation side." monarch " prescription thought is passed on and is used till today from ancient times, this
Invention carries out prescription compatibility according to this principle, and the application in cosmetics has practical significance.Aiming at the problem that skin allergy,
Dialectical analysis and induction and conclusion are carried out to the symptom of skin, obtain solution, the principles of formulating prescriptions using " monarch " are suited the medicine to the illness
Prescribe medicine, comprehensively solve skin problem.
Summary of the invention
It releives antianaphylactic herbal composite the present invention provides one kind, it is prepared by the raw material of following weight proportion
Made of cosmetic additive agent:
Purslane 20-25%, radix scutellariae 10-13%, kuh-seng 10-20%, Asian puccoon 8-15%, root bark of tree peony 4-10%, Salvia japonica 10-
20%, semen coicis 10-20%, fruit of summer cypress 4-10%, radix saposhnikoviae 2-8%, Radix Angelicae Sinensis 2-8%, rhizoma atractylodis 2-8%, Radix Glycyrrhizae 2-8%.
Extraction solvent of the invention: the 1.3- propylene glycol that Extraction solvent is 70%.
Extracting method of the invention, ultrasonic cryogenic extraction.Particular content is as follows:
Pharmaceutical composition and 1.3- propylene glycol are mixed according to the ratio of 1:3, under conditions of temperature is 50-60 DEG C, low speed
Stirring is impregnated 24 hours, and ultrasonic extraction in 30 minutes is then carried out.After extraction, coarse filtration separation, laggard andante formula mistake are carried out
Filter finally carries out low temperature sedimentation, final composite extract is obtained after separation.
The present invention is applied to prepare releive antianaphylactic skin care item, including facial mask, water, essence, milky lotion, cream and washing
In product, additive amount 1-5%.
Purslane extract has the antibiotic property of wide spectrum, and has antiinflammation, can prevent and treat skin eczema, allergic dermatitis,
The skin diseases such as contact dermatitis;There is good oxygen radical removing ability, illustrates that it has apparent oxidation resistant effect;Have good
Skin moisture-keeping.
Radix scutellariae root extract can inhibit elastoser, can eliminate free radical, to increase skin metabolism, increase
Skin elasticity and wrinkle resistance, can be with anti-aging;Promote brain amide, and improving sebum keeps skin soft and moist;It can inhibit dermatitis, enhancing skin
The resistance of skin has anti-inflammatory;The histamine that release can be neutralized, has the ability for preventing allergy.
Kuh-seng is containing there are many alkaloids.There is different inhibiting effect to a variety of biologies and fungi, have antibacterial and anti-inflammatory
Effect;It is cultivated in fiber sprout cell etc., the generation of collagen can be effectively facilitated, there is anti-aging function;With very
Moisturizing well, water holding effect have water supplement function;The decomposition that can promote fat cell, can be used as anoretic.
Radix Arnebiae extract has anti-dermatophyte virus function, and in conjunction with its anti-inflammatory, dermatology is clinically used for treating flat
Wart, psoriasis, dermatitis, eczema etc.;Radix Arnebiae extract has facilitation to cathepsin active, indicates that the extract can enhance
The metabolism of Skin Cell has Antiageing effect in conjunction with its antioxidant.Alkannin is widely used to cure as natural pigment
In medicine, cosmetics industry.
The root of tree peony has anti-inflammatory and anti-allergic effects.It can prevent melanin production, and the production of freckle can be prevented
It is raw.And the effect of skin aging caused by due to peroxidation can be fought.
Salvia japonica has activation to luciferase it is obvious that explanation has anti-inflammatory;There is inhibiting effect to phosphodiesterase,
Mean that the generation for reducing grease can be applied to Firm diet products in conjunction with the contraction that it rolls into a ball collagenous fibres;In skin
Skin thickness can be reduced after upper coating, illustrate there is sun-proof result.
Semen coicis Job's tears seed contains Coixenolide, coixol, the natural products extracted from coix lacryma-jobi seed, has good moisturizing
Effect can improve skin and decline because dark and gloomy caused by drying with metabolic capability.The semen coicis rouge wherein contained can accelerate cortex
Blood circulation, have inhibit melanin formation effect, soft and smooth and conditioning skin, generally with absorption enhancer share can promote treatment
Effect.
The fruit of summer cypress mainly contains the ingredients such as triterpene soap alkali, alkaloid, flavonoids and fat oil, has well to bacterium, tinea bacterium etc.
Inhibiting effect, can be used for preventing and treating the dermatopathies such as psoriasis, have elimination effect to free radical, antioxidant can be made;Have to allergy
Inhibiting effect can make allergy inhibitor;There is inhibiting effect to fat cell activity, anoretic can be made.
Opoponax contains many coumarin compounds and chromogen ketone compound.Radix Saposhnikoviae volatile oil is used to prepare essence on a small quantity;
In the fat cell hydrolysis experiment of test tube, Radix Saposhnikoviae extract has facilitation to fat splitting, can be used for diet products;To more
Kind free radical has elimination effect, can be used as antioxidant;It is known as certain inhibiting effect to black, can be used as whitening product;It can
With pore refining, it is used as astringent;Has the function of antibacterial anti-inflammatory simultaneously.
Effect of the angelica extract based on Radix Angelicae Sinensis activating microcirculation and removing stasis medicinal, improvement skin microcirculation, can be used for the makeup of many promoting blood circulations
Product, such as hair tonic, the secretion of adjustment skin, extra-nutrition, neutralizing black eye;Radix Angelicae Sinensis to the proliferation of blood vessel chrotoplast show it
Promoting blood circulation simultaneously, plays the role of solidifying capillary;Radix Angelicae Sinensis has good SOD sample activity, inhibits film rouge caused by superoxide radical
Matter peroxidization and radical reaction, and with a variety of mechanism antagonism free radicals pair such as biological film phospholipid join protection membrane lipid
The damage of tissue, gloomy to complexion caused by free radical retardance or raw sore swells, there is special efficacy;Activation rate to luciferase and to dry
The proliferation function of cell shows Antiageing effect.
Activated display of the atractylodes chinensis to luciferase, atractylodes chinensis have anti-inflammatory, have to atopic dermatitis
Preventive and therapeutic effect;Some researches show that it to have facilitation to the decomposition of the subcutaneous white adipocyte of mouse, therefore can be used as anoretic, together
When have activation to aromatizing enzyme, make the more female hormone of human secretory, keep the elasticity and gloss of skin.
Proliferation function of the licorice to myocyte, the facilitation to vascular endothelial cell proliferation, to collagen-
The promotion that 4 types generate, the studies have shown thats licorice such as inhibition that NO is generated improve skin in terms of have promotion
Effect, can be used for anti-ageing cosmetics;Licorice has inhibition melanin, the effect of skin whitening simultaneously;To some bacteriums
It significantly inhibits, can be used as anti-inflammatory agent.
Specific embodiment
1 one kind of embodiment is releived the preparation of antianaphylactic herbal composite;
By purslane, radix scutellariae, kuh-seng, Asian puccoon, the root bark of tree peony, Salvia japonica, semen coicis, the fruit of summer cypress, radix saposhnikoviae, Radix Angelicae Sinensis, rhizoma atractylodis, Radix Glycyrrhizae
After washing, it is put into air dry oven, it is sufficiently dry.
Weigh dry purslane: 600g, radix scutellariae 300g, kuh-seng 300g, Asian puccoon 300g, root bark of tree peony 150g, Salvia japonica 200g,
Semen coicis 200g, fruit of summer cypress 150g, radix saposhnikoviae 100g, Radix Angelicae Sinensis 100g, rhizoma atractylodis 100g, Radix Glycyrrhizae 100g are crushed.
The Chinese herbal medicine of crushing is put into constant temperature extracting tank.
70%1.3- propylene glycol 2.6KG is added, temperature maintains 55 DEG C, is slowly stirred, and impregnates 8 hours.
After immersion, progress ultrasonic extraction, interrupted extraction 30 minutes.
It is filtered with plate filter, is put into cryopreservation tank and is settled, settled 72 hours, take the supernatant to be
Finished product.
A kind of application of the antianaphylactic herbal composite in facial mask of releiving of embodiment 2
The constituent and content (%) of facial mask are as follows:
Antianaphylactic Chinese herbal medicine combination: 1.5
Water: 92.55
Glycerol: 3
EDTA:0.05
Sodium Hyaluronate: 0.05
Xanthan gum: 0.1
Carbomer: 0.15
Glycine betaine: 1.5
Arginine: 0.12
1.2- hexylene glycol: 0.5
Parahydroxyacet-ophenone: 0.5
Facial mask the preparation method is as follows:
Antianaphylactic Chinese herbal medicine combine 1.5Kg, water 92.55Kg, glycerol 3Kg, EDTA 0.05Kg, Sodium Hyaluronate
0.05Kg, xanthan gum 0.1Kg, carbomer 0.15Kg, glycine betaine 1.5Kg are put into kettle, are heated to 85 DEG C, are stirred 30 minutes,
It homogeneous 3 minutes, is uniformly dispersed.
40 DEG C of addition arginine 0.12Kg are cooled to, are stirred evenly.
It is down to room temperature and 1.2- hexylene glycol 0.5Kg, parahydroxyacet-ophenone 0.5Kg is added, stir evenly.
Film cloth is added in ready-made facial mask essence, so that it may releive face as people's natural antiallergy used in everyday
Film can be used as skin repair, antiallergy, treatment hormone face and use.
A kind of application of the antianaphylactic herbal composite in frost of releiving of embodiment 3
The constituent and content (%) of frost are as follows:
Antianaphylactic Chinese herbal medicine combination: 3
Water: 80.9
Glycerol: 3
EDTA:0.05
Sodium Hyaluronate: 0.05
Acrylamide dimethyltaurine ammonium/VP copolymer: 1
Glycine betaine: 1.5
The smooth olive oleate of cetearyl glucoside, sorb, cetostearyl alcohol: 1.5
Caprylic/capric triglyceride: 8
1.2- hexylene glycol: 0.5
Parahydroxyacet-ophenone: 0.5
Frost the preparation method is as follows:
Antianaphylactic Chinese herbal medicine combine 3Kg, water 80.9Kg, glycerol 3Kg, EDTA 0.05Kg, Sodium Hyaluronate
0.05Kg, acrylamide dimethyltaurine ammonium/VP copolymer 1 Kg, glycine betaine 1.5Kg are put into emulsion pot, are heated to 85 DEG C,
Stirring 30 minutes, homogeneous 3 minutes, is uniformly dispersed.
By cetearyl glucoside, the smooth olive oleate of sorb, cetostearyl alcohol 1.5Kg, caprylic/capric triglyceride
Oil cauldron, 85 DEG C of dissolutions are added in 8Kg.It is down to room temperature and 1.2- hexylene glycol 0.5Kg, parahydroxyacet-ophenone 0.5Kg is added, stir evenly.
Ready-made face cream has effects that moisturizing moisturizing is repaired, and can be used as skin repair, antiallergy, treatment hormone face and uses.
Claims (5)
- The antianaphylactic herbal composite 1. one kind is releived, it is characterised in that: containing purslane, radix scutellariae, kuh-seng, Asian puccoon, the root bark of tree peony, Salvia japonica, semen coicis, the fruit of summer cypress, radix saposhnikoviae, Radix Angelicae Sinensis, rhizoma atractylodis, Radix Glycyrrhizae.
- 2. antianaphylactic herbal composite of releiving as described in claim 1, which is characterized in that the content of its composition by with Lower mass percent composition: purslane 20-25%, radix scutellariae 10-13%, kuh-seng 10-20%, Asian puccoon 8-15%, root bark of tree peony 4-10%, Salvia japonica 10-20%, semen coicis 10-20%, fruit of summer cypress 4-10%, radix saposhnikoviae 2-8%, Radix Angelicae Sinensis 2-8%, rhizoma atractylodis 2-8%, Radix Glycyrrhizae 2- 8%.
- 3. such as the extraction preparation method of the described in any item antianaphylactic herbal composites of releiving of claim 1 and 2, feature It is, prepares as follows:(1) by the cleaning compositions in claim 1, drying, crushing;(2) the 1.3- propylene glycol that Extraction solvent is 70%;(3) extraction process is ultrasonic cryogenic extraction.
- 4. the extraction preparation method for antianaphylactic herbal composite of releiving as described in right 3, which is characterized in that extract special Sign is that solid-to-liquid ratio 1:3 carries out low temperature extraction, and pharmaceutical composition and 1.3- propylene glycol are mixed according to the ratio of 1:3, are 50- in temperature Under conditions of 60 DEG C, immersion 24 hours is stirred at low speed, then carries out ultrasonic extraction in 30 minutes, after extraction, carries out coarse filtration Separation, carries out plate-type filtering afterwards, finally carries out low temperature sedimentation, final composite extract is obtained after separation.
- 5. the antianaphylactic herbal composite of releiving as described in right 1, which is characterized in that releive applied to preparation antianaphylactic In skin care item, including facial mask, water, essence, milky lotion, cream and cleaning product, additive amount 1-5%.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910182961.1A CN109718185A (en) | 2019-03-12 | 2019-03-12 | One kind is releived antianaphylactic herbal composite |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910182961.1A CN109718185A (en) | 2019-03-12 | 2019-03-12 | One kind is releived antianaphylactic herbal composite |
Publications (1)
Publication Number | Publication Date |
---|---|
CN109718185A true CN109718185A (en) | 2019-05-07 |
Family
ID=66302181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201910182961.1A Pending CN109718185A (en) | 2019-03-12 | 2019-03-12 | One kind is releived antianaphylactic herbal composite |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109718185A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111467447A (en) * | 2020-04-18 | 2020-07-31 | 北温草生物科技(上海)有限公司 | Chinese herbal medicine composition for inhibiting skin allergy |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101224287A (en) * | 2007-12-27 | 2008-07-23 | 佟家勇 | Oral administration Chinese traditional medicine for treating acne and preparing method thereof |
CN101584773A (en) * | 2009-06-10 | 2009-11-25 | 张学贵 | Chinese herbal medicament for treating skin diseases |
CN103127269A (en) * | 2011-12-05 | 2013-06-05 | 上海原尚草化妆品有限公司 | Extractive of Chinese herbal compound and cosmetics including active ingredients |
CN104257528A (en) * | 2014-08-07 | 2015-01-07 | 天津郁美净集团有限公司 | Traditional Chinese medicine active matter composition and application thereof in cosmetics |
CN107753378A (en) * | 2017-11-18 | 2018-03-06 | 上海煓梅生物科技有限公司 | A kind of extracts of Chinese herbal medicine and its preparation method and application |
CN108514572A (en) * | 2018-05-24 | 2018-09-11 | 重庆市中医院 | Chinese medicine composition, extract and preparation a kind of anti-inflammatory and that repair skin barrier |
-
2019
- 2019-03-12 CN CN201910182961.1A patent/CN109718185A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101224287A (en) * | 2007-12-27 | 2008-07-23 | 佟家勇 | Oral administration Chinese traditional medicine for treating acne and preparing method thereof |
CN101584773A (en) * | 2009-06-10 | 2009-11-25 | 张学贵 | Chinese herbal medicament for treating skin diseases |
CN103127269A (en) * | 2011-12-05 | 2013-06-05 | 上海原尚草化妆品有限公司 | Extractive of Chinese herbal compound and cosmetics including active ingredients |
CN104257528A (en) * | 2014-08-07 | 2015-01-07 | 天津郁美净集团有限公司 | Traditional Chinese medicine active matter composition and application thereof in cosmetics |
CN107753378A (en) * | 2017-11-18 | 2018-03-06 | 上海煓梅生物科技有限公司 | A kind of extracts of Chinese herbal medicine and its preparation method and application |
CN108514572A (en) * | 2018-05-24 | 2018-09-11 | 重庆市中医院 | Chinese medicine composition, extract and preparation a kind of anti-inflammatory and that repair skin barrier |
Non-Patent Citations (1)
Title |
---|
蔡津生, 上海科学技术文献出版社 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111467447A (en) * | 2020-04-18 | 2020-07-31 | 北温草生物科技(上海)有限公司 | Chinese herbal medicine composition for inhibiting skin allergy |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN107737041A (en) | A kind of novel skin antiallergic maintenance composition, skin repair frost and preparation method thereof | |
CN103479775B (en) | Scraping liniment and preparation method thereof | |
CN103816087A (en) | Whitening, sun-resistant and spot removing cosmetic of traditional Chinese medicine composition, and preparation method thereof | |
WO2017092176A1 (en) | Whitening and anti-wrinkle traditional chinese medicine composition, mixed extract thereof and application thereof | |
CN109010115A (en) | A kind of Shu Min creams with anti-inflammatory efficacy | |
CN104814908A (en) | Mask with effects of resisting wrinkle and tendering skin | |
CN105106103A (en) | Traditional Chinese medicine skincare product and preparation method thereof | |
CN108938493A (en) | A kind of Chinese medicine composition and its preparation method and application | |
CN112043661B (en) | Whitening aloe gel and preparation method thereof | |
CN106880563A (en) | A kind of Chinese medicine skin whitening, moisturizing gel frost and preparation method thereof | |
CN103041042B (en) | Tibetan medicine composition and application of composition in anti-off hair products | |
KR20050073918A (en) | Cosmetic composition comprising plant extract having anti-aging effect | |
KR20050002581A (en) | Cosmetic composition using a herb medicine | |
CN101234132A (en) | New use of angelica sinensis or its extract in preparing skin care products | |
CN113288854A (en) | Traditional Chinese medicine formula anti-aging whitening moisturizing mask and preparation method thereof | |
CN105878107A (en) | Skin-care product composition for sensitive skin | |
KR100891986B1 (en) | Cosmetic composition containing herb medicine extracts and powders | |
CN108785196A (en) | A kind of composition for smoothing acne hole acne print and its application in cosmetics | |
CN105030575A (en) | Rose health bathing powder and preparation method thereof | |
CN111329829A (en) | Traditional Chinese medicine mask and preparation method thereof | |
CN109718185A (en) | One kind is releived antianaphylactic herbal composite | |
CN105816663A (en) | Traditional Chinese medicine composition with nutrition and anti-aging effects and facial cream and preparation methods thereof | |
CN109431951A (en) | A kind of Chinese medicine lightening compositions and preparation method thereof | |
CN105342966A (en) | Skin care moisturizer containing hirudo nipponia and preparation method of skin care moisturizer | |
CN109568230A (en) | A kind of Chinese medicine cosmetic of the anti-aging of moisturizing whitening |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190507 |
|
RJ01 | Rejection of invention patent application after publication |