CN112043661B

CN112043661B - Whitening aloe gel and preparation method thereof

Info

Publication number: CN112043661B
Application number: CN202011138390.0A
Authority: CN
Inventors: 马春雨; 范贺丽; 郭永民; 陈丽红
Original assignee: Zhengzhou Kelly Lai Biotechnology Co ltd
Current assignee: Zhengzhou Kelly Lai Biotechnology Co ltd
Priority date: 2020-10-22
Filing date: 2020-10-22
Publication date: 2023-02-03
Anticipated expiration: 2040-10-22
Also published as: CN112043661A

Abstract

The invention provides a whitening aloe gel and a preparation method thereof, wherein the whitening aloe gel comprises the following components in percentage by weight: polyacrylate crosslinked polymer-6.5%, acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer 1%, SOLAGUM AX0.3%, polyethylene glycol-75%, 2501Cosmetic Wax 3%, dipropylene glycol 4%, moistShield HA eight kinds of hyaluronic acid COMPLEX 0.05%, p-hydroxyacetophenone 0.2%, ALISTIN Alistine 2%, ANTI IRRITATION COMPLEX PLUS 2%, triethanolamine 1.2%, essence 0.01%, aloe extract 2-4%, purslane extract 1-3%, chinese medicine extract 1-3%, and the balance of deionized water; the preparation method of the whitening aloe gel disclosed by the invention is convenient to process, the raw material source is wide, the whitening aloe gel can inhibit the generation of melanin, reduce pigmentation caused by ultraviolet irradiation, fade chloasma and brighten skin color, and meanwhile, the whitening aloe gel has excellent skin feel and pleasant and transparent luster.

Description

Whitening aloe gel and preparation method thereof

Technical Field

The invention relates to the technical field of skin care products, and particularly relates to whitening aloe gel and a preparation method thereof.

Background

Aloe vera, known as "all-purpose adhesive", is widely used in the cosmetics industry, and is also a popular trend as a whitening skin care product. Through continuous research, the aloe is rich in various effective components, not only has the effect of wound healing, but also has the function of inhibiting human epidermal melanocyte tyrosinase and melanin pigmentation caused by ultraviolet irradiation so as to achieve the effect of whitening the skin. The purslane extract has good scavenging capacity for oxygen free radicals, has obvious effects of resisting oxidation and delaying aging, increases skin elasticity, is prepared from the' good prescription complete, has the efficacy of nourishing liver and kidney, is mainly used for treating chloasma, and can improve skin microcirculation. According to the special whitening effect of aloe, the natural purslane extract is matched, and the traditional Chinese medicine extracting solution is prepared into the aloe gel with the natural whitening effect.

Disclosure of Invention

The invention aims to provide a whitening aloe gel with the functions of moisturizing, whitening, removing freckles and resisting aging.

The invention also discloses a preparation method of the whitening aloe gel, which has wide raw material source and convenient preparation and processing.

In order to achieve the purpose, the invention adopts the technical scheme that: the whitening aloe gel comprises the following components in percentage by weight: 60.5 percent of polyacrylate cross-linked polymer, 1 percent of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.3 percent of SOLLAUMTMAX, 0.3 percent of polyethylene glycol-752 percent of 2501cosmetic Wax, 4 percent of dipropylene glycol, 0.05 percent of eight hyaluronic acid compounds of MoistShield H HA, 0.2 percent of p-hydroxyacetophenone, 2 percent of ALISTIN Alistine, 2 percent of ANTI IRISTTATION COMPLEX PLUS, 1.2 percent of triethanolamine, 0.01 percent of essence, 2-4 percent of aloe extract, 1-3 percent of purslane extract, 1-3 percent of traditional Chinese medicine extract and the balance of deionized water.

Wherein, the weight percentage of the aloe extract is 3 percent, the weight percentage of the purslane extract is 2 percent, and the weight percentage of the traditional Chinese medicine extracting solution is 2 percent.

Wherein the traditional Chinese medicine extracting solution consists of the following raw materials in percentage by mass: 18 parts of prepared rehmannia root, 20 parts of Chinese yam, 15 parts of poria cocos, 15 parts of rhizoma alismatis, 12 parts of golden cypress, 12 parts of chrysanthemum, 9 parts of moutan bark, 9 parts of dogwood fruit, 9 parts of wolfberry fruit and 9 parts of dried orange peel.

Further, the preparation method of the whitening aloe gel comprises the following steps:

(1) Weighing a certain amount of deionized water, pouring the deionized water into a dry and clean beaker, then sequentially weighing a certain amount of polyacrylate cross-linked polymer-6 and acrylic acid (acrylate)/C10-30 alkanol acrylate cross-linked polymer according to the weight percentage, adding the weighed materials into the beaker, uniformly stirring the materials by using a glass rod, and homogenizing the materials for 3min by using a homogenizer to obtain a solution A;

(2) Weighing a certain amount of eight hyaluronic acid compounds, namely SOLAGUMTMAX, polyethylene glycol-75, 2501CosmeticWAx and MoistShieldTMHA in sequence according to the weight percentage, adding the eight hyaluronic acid compounds into the solution A, carrying out micro-homogenization until a material body rolls, and completely dispersing and dissolving the material body to obtain a solution B;

(3) Putting a beaker on a heating device, starting heating and stirring, stopping heating after heating to 85 ℃, then putting the beaker in cold water, cooling to 60 ℃, adding a dipropylene glycol and p-hydroxyacetophenone mixed solution into the solution while stirring, fully and uniformly mixing the solution, then weighing a certain amount of ALISTIN Alistine, ANTI IRRITATION OMPLEX PLUS and triethanolamine according to weight percentage, and uniformly stirring;

(4) And (3) continuously stirring and cooling to 45 ℃, sequentially weighing a certain amount of essence, aloe extract, purslane extract and traditional Chinese medicine extract according to the weight percentage, adding the essence, the aloe extract, the purslane extract and the traditional Chinese medicine extract into the solution, continuously stirring to fully and uniformly mix the solution, and standing and cooling to 38 ℃ to obtain the essence.

The preparation method of the traditional Chinese medicine extracting solution comprises the following steps:

(1) Weighing the traditional Chinese medicine extract according to the proportion of each component in a dry medicine spoon in a scale room;

(2) Mixing 3 parts of dogwood fruit, 2.5 parts of tree peony bark, 9 parts of tangerine peel and 20 parts of Chinese yam, placing the mixture into a drying and crushing machine to be ground into fine powder, adding water to decoct for 3 hours, filtering, and concentrating the filtrate to 2/3 to obtain a solution 1;

(3) Decocting 15 parts of rhizoma Alismatis and 15 parts of Poria in water twice (3 hr for the first time and 2 hr for the second time), filtering, mixing filtrates, and concentrating to 2/3 to obtain solution 2;

(4) Decocting 18 parts of radix rehmanniae Preparata in water for three times, namely 3 hours for the first time, 2 hours for the second time and 1 hour for the third time, filtering, mixing filtrates, and concentrating to 2/3 to obtain a solution 3;

(5) Soaking 9 parts of fructus Lycii in 45% ethanol for 24 hr, collecting percolate, placing in evaporating dish, and volatilizing until ethanol smell disappears to obtain solution 4;

(6) Soaking the rest 6 parts of Corni fructus, 6.5 parts of cortex moutan, 12 parts of cortex Phellodendri and 12 parts of flos Chrysanthemi in 70% ethanol for 24 hr, collecting percolate, placing in evaporating dish, and volatilizing until ethanol smell disappears to obtain solution 5;

(7) Mixing the above solutions 1-5, and mixing to obtain Chinese medicinal extractive solution.

The invention has the beneficial effects that:

the components in the formula of the whitening aloe gel provided by the invention fully play roles, and the components are subjected to synergistic reaction, so that the formula effect is more remarkable, the most effective proportion is obtained through multiple tests, the aloe gel with the whitening effect is developed, the aloe extract, the purslane extract and the traditional Chinese medicine extracting solution are added, so that multiple effects are mutually and synergistically complemented, the whitening effect is jointly achieved, the purslane extract has good scavenging capacity for oxygen radicals, and has an obvious antioxidation effect, the traditional Chinese medicine extracting solution contains natural whitening, moisturizing and anti-aging components, the skin barrier can be repaired, the water loss is reduced, the skin microcirculation is improved, and the whitening effect is more remarkable due to the matching of the aloe extract with the purslane extract and the traditional Chinese medicine extracting solution.

The polyacrylate crosslinked polymer-6 is a high molecular polymer, is used as a thickening agent and a film-forming agent in cosmetics, is produced by a traditional polymerization process, is resistant to high electrolytes, is stable to shearing force and ultraviolet light, and has good suspension stability, and the thickening capability comes from the interaction between electrostatic repulsion and hydrophobic groups.

The acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer is prepared by crosslinking poly (acrylic acid) polymer and allyl sucrose or allyl pentaerythritol, and has the characteristics of smoothness and long fluidity. High transparency, and has the effect of keeping the formula stable, so that the skin feel is rich, smooth and pleasant.

Solarumax consists of gum arabic and xanthan gum. The acacia gum is natural gum prepared by extracting plant juice from Acacia Senticosa of Mimosaceae of Leguminosae such as Acacia senegal and Acacia seyi. Similar to the state of natural skin cells, the skin repair liquid has the functions of whitening and tendering skin, can repair injured skin, has ideal recovery effect on striae gravidarum skin, can repair partial light scars and does not cause allergy; the xanthan gum is dispersed and emulsified in water to form stable hydrophilic viscous colloid; is biological glue integrating thickening, suspending, emulsifying and stabilizing.

The polyethylene glycol-75 mainly acts as a solvent and an adhesive in the skin care product and has no pox-causing property.

The 2501Cosmetic Wax has good moisture retention and good absorption when contacting with the skin, so that the skin is more moist. Can reduce sticky feeling and has good skin feeling. Good air permeability, and no blackhead or acne on skin.

Dipropylene glycol is the most desirable solvent for many flavor and fragrance and cosmetic applications, and this material has good water, oil and hydrocarbon co-melting ability, and is mild in odor and excellent in quality.

The eight hyaluronic acid compounds of MoistShieldTMHA have excellent moisturizing and lubricating properties, are commonly called as 'natural moisturizing factors', form a hydrated film on the surface of skin, have 1000 times of water locking capacity, and well increase the water in the horny layer of the skin. The small molecular hyaluronic acid can permeate into the dermis of the skin, supplement hyaluronic acid in the skin, regulate skin metabolism, promote blood circulation, moisten, smooth, fine and soft the skin, delay skin aging and have the effects of resisting senility and wrinkles. It also helps to repair damage of epidermis and eliminate oxygen free radical generated by sun exposure, and has sunscreen effect.

The p-hydroxyacetophenone is obtained by acylating and translocating phenol, and is used together with the traditional preservative, so that the dosage of the traditional preservative can be reduced, and the sterilization is comprehensively accelerated. Has multiple effects of resisting oxidation, resisting stimulation and protecting products.

The ALISTIN Alistine (decarboxylated carnosine HCl) has effects of capturing hydroxyl free radical, simple substance oxygen and hydrogen peroxide free radical, and can inhibit lipid oxidation caused by non-metal ions, and stably protect cell membrane. The glycosylation is performed on the skin, which can cause the gradual loss of elasticity of collagen, wrinkle formation on the surface of the skin, yellow skin color and the like, and the decarboxylated carnosine inhibits the glycosylation of structural protein through two different target points, thereby protecting the collagen and the elastin and brightening the skin color.

The ANTI IRRITATION COMPLEX PLUS is prepared by compounding centella asiatica extract, polygonum cuspidatum root extract, scutellaria baicalensis root extract, tea leaf extract, glycyrrhiza glabra root extract, matricaria chamomilla flower extract and rosemary leaf extract;

the centella asiatica extract is commonly called plant collagen, and can promote skin collagen regeneration, enhance cell basal layer cell activity and keep skin elastic and compact; resisting oxidation, inhibiting free radical activity, regulating skin immunity, removing melanin pigmentation, regenerating skin cells, increasing skin water retention, and activating and regenerating skin cells;

the giant knotweed rhizome extract mainly comprises resveratrol and emodin, can inhibit the activity of melanocytes and has the function of promoting the activity of macrophages, and the giant knotweed rhizome extract can reduce the content of melanin on the skin and brighten the skin color from the two points, has the function of inhibiting elastase, and can resist wrinkles and reduce wrinkles;

the radix Scutellariae extract has effects of inhibiting various skin pathogenic fungi, resisting inflammation, resisting allergy, repairing sunburned skin, absorbing ultraviolet ray, scavenging oxygen free radical, inhibiting melanin generation, and cleaning and smoothing skin. Flavonoids, zinc baicalin and copper baicalin have obvious scavenging effect on superoxide radicals and can protect skin cells from excessive oxidation of oxygen radicals;

the tea polyphenol compounds in the tea extract are sensitive to ultraviolet rays, especially have strong absorption peak to ultraviolet rays with wavelength of 2000-3300 angstroms causing solar dermatitis, and reduce melanin deposition. Has strong antioxidant ability, and has effects in scavenging active oxygen free radicals higher than vitamin C and vitamin E, and relieving skin aging;

the raw material of the glycyrrhiza glabra root extract is very precious, the extraction process is difficult, and the glycyrrhiza glabra root extract is known as 'whitening gold' in the world of cosmetics. The skin whitening and freckle removing cream can penetrate into the skin to keep high activity, effectively inhibit the activity of tyrosinase, reduce the generation of melanin, and has quick, efficient, green and safe whitening and freckle removing effects;

the chamomile extract can well relieve skin and resist skin sensitivity, has the functions of anti-inflammation, antibiosis and antioxidation, and can play a role in quickly relieving skin problems by relieving and deeply moisturizing;

rosemary leaf extract is a powerful natural antioxidant. The extract contains rich rosmarinic acid, which is obtained by extracting rosemary and has strong antioxidant activity, and the antioxidant activity of the extract is stronger than that of vitamin E, caffeic acid, chlorogenic acid, folic acid and the like. It can effectively remove active oxygen in environmental pollution, inhibit melanin formation, and has excellent whitening and moisturizing effects.

The triethanolamine serving as a neutralizer in the cosmetics can achieve the effects of thickening and moisturizing, and the cream in the cream preparation is more exquisite and bright white, so that the stability of the product quality is ensured while the use experience is increased.

The aloe extract is rich in various vitamins, the vitamins include vitamin B1, vitamin B2, vitamin C, vitamin E and nicotinamide, and also include polysaccharide compounds and essential amino acids, and show various biological activities, the contained active substances have the effects of promoting the growth of fibrin, inhibiting elastase, promoting the synthesis of collagen and removing hydroxyl free radicals, and have obvious effects of activating skin and resisting aging. In addition, the aloe extract can play the roles of sun screening, anti-inflammation, oxidation resistance and moisture preservation.

The herba Portulacae extract is rich in flavonoids, epinephrine, polysaccharides, various vitamins, amino acids, etc. The plant polysaccharides and vitamins can nourish and lubricate skin, promote normal physiological function of epithelial cells, and reduce generation of dead skin and stratum corneum caused by dryness. The amino acids can contract vascular smooth muscle, and has effects of contracting central and peripheral nature, relieving skin and inhibiting skin pruritus caused by dryness. The flavone and saponin can remove free radicals, resist oxidation, and delay skin aging. The alkaloids and flavones can be used for resisting bacteria and inhibiting common pathogenic dermatophytes.

The traditional Chinese medicine extract contains various active ingredients, the prepared rehmannia root contains catalpol, digitonin, saccharides and the like, can change the composition of sebum, and can inhibit the generation of grease by combining the inoxidizability of the extract and the moisture absorption capacity in a low-temperature environment, soften the skin and moisten the skin. The Chinese yam contains Chinese yam polysaccharide and various amino acids, and can activate skin, resist wrinkle, preserve moisture, resist oxidation and condition skin. Poria mainly contains other effective components such as polysaccharide, and has effects of promoting synthesis, shrinking pore, tightening skin, and removing fine wrinkles. The Alismatis rhizoma extract has effects in inhibiting elastase, resisting oxidation, and resisting aging. Cortex Phellodendri and flos Chrysanthemi extract can be used for regulating skin. Cortex moutan and Corni fructus extract have effects of activating skin, whitening skin, and resisting oxidation. The fructus Lycii extract has effects of preventing red blood streak, resisting aging, and promoting immunity. Pericarpium Citri Tangerinae contains hesperidin and hesperetin, and volatile oil has antiinflammatory and antioxidant effects. The compatibility of the Chinese medicines and the mutual cooperation of other components can achieve multiple whitening effects together.

Detailed Description

The invention is further illustrated by the following examples.

Example 1: the whitening aloe gel comprises the following components in percentage by weight: 60.5 percent of polyacrylate cross-linked polymer, 1 percent of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.3 percent of SOLLAUMTMAX, 0.2 percent of polyethylene glycol-752 percent, 2501Cosmetic Wax 3 percent, 4 percent of dipropylene glycol, 0.05 percent of eight hyaluronic acid compounds of MoistShield dTMAH A, 0.2 percent of p-hydroxyacetophenone, 2 percent of ALISTIN Alistine, 2 percent of ANTI IRTATION COMPLEX PLUS, 1.2 percent of triethanolamine, 0.01 percent of essence, 3 percent of aloe extract, 2 percent of purslane extract, 2 percent of traditional Chinese medicine extract and the balance of deionized water.

The preparation method of the whitening aloe gel comprises the following steps:

(1) Weighing a certain amount of deionized water, pouring the deionized water into a dry and clean beaker, then sequentially weighing a certain amount of polyacrylate cross-linked polymer-6 and acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer according to the weight percentage, adding the weighed materials into the beaker, uniformly stirring the materials by using a glass rod, and homogenizing the materials for 3min by using a homogenizer to obtain a solution A;

(4) And continuously stirring and cooling to 45 ℃, then sequentially weighing a certain amount of essence, aloe extract, purslane extract and traditional Chinese medicine extract according to the weight percentage, adding the essence, the aloe extract, the purslane extract and the traditional Chinese medicine extract into the solution, continuously stirring to fully and uniformly mix the solution, and standing and cooling to 38 ℃ to obtain the essence.

(2) Mixing 3 parts of fructus Corni, 2.5 parts of cortex moutan, 9 parts of pericarpium Citri Tangerinae and 20 parts of rhizoma Dioscoreae, pulverizing into fine powder in a drying pulverizer, decocting in water for 3 hr, filtering, and concentrating the filtrate to 2/3 to obtain solution 1;

(4) Decocting 18 parts of radix rehmanniae Preparata with water for three times, the first time for 3 hours, the second time for 2 hours and the third time for 1 hour, filtering, mixing filtrates, and concentrating to 2/3 to obtain solution 3;

Example 2: the whitening aloe gel comprises the following components in percentage by weight: 60.5 percent of polyacrylate cross-linked polymer, 1 percent of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.3 percent of SOLLAUMTMAX, 0.3 percent of polyethylene glycol-752 percent of 2501cosmetic Wax, 4 percent of dipropylene glycol, 0.05 percent of eight hyaluronic acid complexes of MoistShield H HA, 0.2 percent of p-hydroxyacetophenone, 2 percent of ALISTIN Alistine, 2 percent of ANTI IRISTTATION COMPLEX PLUS, 1.2 percent of triethanolamine, 0.01 percent of essence, 4 percent of aloe extract, 1 percent of purslane extract, 1 percent of traditional Chinese medicine extract and the balance of deionized water.

The preparation method of the whitening aloe gel and the traditional Chinese medicine extracting solution is the same as that of the example 1.

Example 3: the whitening aloe gel comprises the following components in percentage by weight: 60.5 percent of polyacrylate cross-linked polymer, 1 percent of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.3 percent of SOLLAUMTMAX, 0.2 percent of polyethylene glycol-752 percent, 3 percent of 2501Cosmetic Wax, 4 percent of dipropylene glycol, 0.05 percent of eight hyaluronic acid compounds of MoistShield dTMAH, 0.2 percent of p-hydroxyacetophenone, 2 percent of ALISTIN Alistine, 2 percent of ANTI IRTATION COMPLEX PLUS, 1.2 percent of triethanolamine, 0.01 percent of essence, 2 percent of aloe extract, 3 percent of purslane extract, 3 percent of traditional Chinese medicine extract and the balance of deionized water.

Example 4: the whitening aloe gel comprises the following components in percentage by weight: 60.5 percent of polyacrylate cross-linked polymer, 1 percent of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.3 percent of SOLLAUMTMAX, 0.2 percent of polyethylene glycol-752 percent, 2501Cosmetic Wax 3 percent, 4 percent of dipropylene glycol, 0.05 percent of eight hyaluronic acid compounds of MoistShield dTMAH A, 0.2 percent of p-hydroxyacetophenone, 2 percent of ALISTIN Alistine, 2 percent of ANTI IRTATION COMPLEX PLUS, 1.2 percent of triethanolamine, 0.01 percent of essence, 3 percent of aloe extract, 2 percent of traditional Chinese medicine extract and the balance of deionized water.

The preparation method of the whitening aloe gel is the same as that of example 1, except that the purslane extract is not added into the whitening aloe gel.

Example 5: the whitening aloe gel comprises the following components in percentage by weight: 60.5 percent of polyacrylate cross-linked polymer, 1 percent of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.3 percent of SOLLAUMTMAX, 0.2 percent of polyethylene glycol-752 percent, 2501Cosmetic Wax 3 percent, 4 percent of dipropylene glycol, 0.05 percent of eight hyaluronic acid complexes of MoistShield dTMAH, 0.2 percent of p-hydroxyacetophenone, 2 percent of ALISTIN Alistine, 2 percent of ANTI IRTATION COMPLEX PLUS, 1.2 percent of triethanolamine, 0.01 percent of essence, 3 percent of aloe extract, 2 percent of purslane extract and the balance of deionized water.

The whitening aloe gel is prepared by the same steps as example 1 without adding any traditional Chinese medicine extract.

Effect experiment:

study subjects: 50 healthy women of 25-35 years old were divided into five groups of 10 persons/group on a parallel, randomized basis.

The first group of subjects used the whitening aloe vera gel prepared according to example 1 daily;

the second group of subjects used the whitening aloe vera gel prepared according to example 2 daily;

the third group of subjects used the whitening aloe vera gel prepared according to example 3 daily;

a fourth group of subjects used the whitening aloe vera gel prepared according to example 4 daily;

a fifth group of subjects used the whitening aloe vera gel prepared according to example 5 daily;

the corresponding skin care products are used by the testee once in the morning and at night every day, and are not used with other skin care products during the test period.

The experimental results are as follows:

1. melanin content (MI value)

Table 1: MI value of melanin content of the same part in the fourth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	165	163	166	165	158	169	156	165	159	161
Example 2	159	162	170	158	159	164	164	154	163	162
											Example 3	169	170	168	157	160	153	161	159	165	161
Example 4	165	159	156	152	165	158	154	169	170	173
											Example 5	155	162	161	158	168	163	156	158	160	155

Table 2: MI value of melanin content of the same part in the eighth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	120	132	135	125	131	143	120	134	122	130
Example 2	138	142	145	140	136	150	135	129	138	142
											Example 3	135	146	138	136	135	133	129	131	135	137
Example 4	149	145	139	142	145	138	146	151	148	149
											Example 5	146	150	142	145	149	143	148	146	145	142

Note: the MI value of the skin melanin content is indicative of the melanin index, and the larger the MI value, the higher the skin melanin content.

As shown in tables 1 and 2, the skin melanin content of the test subjects is significantly reduced after the whitening aloe gel prepared in example 1 is used, i.e., the whitening aloe gel provided by the present invention has a better effect.

2. Heme (red pigment) content

Table 3: the hemoglobin content of the same part in the periphery

	1	2	3	4	5	6	7	8	9	10
											Example 1	310	319	297	298	315	288	285	320	319	318
Example 2	311	315	331	312	298	301	296	281	313	307
											Example 3	300	316	297	298	315	298	285	320	329	318
Example 4	305	315	323	295	314	296	297	315	317	296
											Example 5	315	316	297	288	315	292	285	310	329	318

Table 4: hemoglobin content of the same part in the eighth week

Note: human skin tends to be redder when hemoglobin content is higher.

As can be seen from tables 3 and 4, the skin color improvement effect of the subjects was better after the whitening aloe gel prepared in example 1 was used.

3. Skin color difference ITA DEG value

Table 5: skin complexion change of the same part of the skin in the fourth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	38	39	40	39	37	38	40	36	38	39
Example 2	41	40	38	37	39	42	41	38	36	42
											Example 3	38	39	40	41	39	43	38	37	39	40
Example 4	38	37	41	40	42	37	41	39	43	42
											Example 5	44	38	39	36	39	43	39	42	42	38

Table 6: skin complexion change of the same part in the eighth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	55	53	50	48	53	50	51	48	49	48
Example 2	48	48	47	46	45	48	50	46	45	50
											Example 3	51	46	45	49	48	50	48	47	47	48

Example 2	43	48	42	45	42	46	45	46	45	52
											Example 2	45	46	47	42	41	44	42	43	43	46

Note: a represents the red-green shade, + a represents red, -a represents green; b denotes the degree of blue-yellow, + b denotes yellow, -b denotes blue; the ITA ° value (individual type angle) characterizes the skin brightness, and is calculated by the following formula, wherein the larger the ITA ° value is, the brighter the skin is, and conversely, the darker the skin is.

ITA°＝[Arctan(L*-50/b*)]×180/π

From table 5, table 6, it can be seen that the skin color lightening effect of the subjects was better after using the whitening aloe gel prepared according to example 1.

4. Water content

Table 7: the moisture content of the skin at the same part in the fourth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	39.3	40.2	46.9	45.2	48.3	48.5	39.7	49.8	48.1	39.7
Example 2	41.3	39.9	48.3	49.1	49.6	51.2	51.3	48.5	47.1	38.5
											Example 3	37.5	39.4	44.5	47.5	50.6	48.3	48.1	51.2	49.3	38.8
Example 4	41.4	41.3	38.8	49.3	47.3	49.8	49.4	48.7	49.6	42.5
											Example 5	39.2	38.9	41.7	48.6	50.1	51.5	51.8	48.6	47.5	49.8

Table 8: moisture content of the skin of the same part in the eighth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	62.4	60.3	62.5	60.5	61.2	61.3	63.4	68.6	69.1	59.2
Example 2	60.4	58.3	58.6	59.7	59.8	57.4	58.7	62.8	60.7	57.5
											Example 3	59.8	59.1	60.8	57.3	58.6	60.8	59.5	62.7	61.5	58.9
Example 4	57.5	59.8	57.3	56.7	57.5	58.5	56.7	57.3	57.6	56.8
											Example 5	57.4	59.3	58.5	57.7	56.5	56.6	57.9	56.3	58.9	58.1

Note: the larger the value, the higher the skin moisture content.

From table 7 and table 8, it can be seen that the moisture content of the skin of the subject is increased and the moisturizing effect is better after the whitening aloe gel prepared according to example 1 is used.

5. TEWL value of percutaneous water loss

Table 9: TEWL value of the same skin part in the periphery

	1	2	3	4	5	6	7	8	9	10
											Example 1	29.21	30.14	29.17	29.31	30.22	31.26	28.71	29.75	27.38	30.85
Example 2	28.67	27.81	30.63	28.66	29.15	30.45	26.78	29.98	26.71	31.25

Example 3	30.33	29.87	31.24	28.49	28.35	28.68	30.45	27.38	27.51	30.43
											Example 4	28.76	29.69	30.73	29.78	28.59	31.22	27.65	26.17	29.87	30.23
Example 5	29.67	30.55	29.64	30.66	31.45	30.66	27.52	28.49	30.01	26.41

Table 10: the TEWL value of the same part of skin after percutaneous water loss in the eighth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	22.74	25.51	22.11	21.35	22.46	25.43	19.42	21.34	22.37	23.62
Example 2	19.31	20.93	21.11	19.34	20.64	21.16	17.47	18.12	19.23	19.62
											Example 3	20.45	18.32	20.85	18.13	19.43	19.35	18.67	19.36	18.61	20.25
Example 4	19.11	20.33	18.31	18.26	19.32	18.32	18.57	16.78	20.45	21.47
											Example 5	18.43	19.15	20.32	19.43	19.76	19.43	18.45	19.33	17.53	19.34

Note: the skin water dispersion reflects the change rule of skin moisture loss along with time in a test period, and the smaller the value is, the less the moisture loss is, and the better the barrier function of the skin is.

From tables 9 and 10, it can be seen that the skin of the test subjects has less moisture loss through the skin and the barrier function of the skin care product is better after the test subjects use the whitening aloe gel prepared according to example 1.

6. Skin elasticity

Table 11: the skin elasticity of the same part in the fourth week%

	1	2	3	4	5	6	7	8	9	10
											Example 1	59.70	60.75	58.67	61.67	58.54	58.76	60.22	59.56	58.45	57.21
Example 2	59.89	59.53	59.56	60.56	61.45	59.34	59.71	62.33	58.76	61.25
											Example 3	58.78	58.45	60.46	60.57	58.71	58.56	60.73	61.34	59.56	60.63
Example 4	60.31	58.97	58.87	59.46	60.41	57.31	59.34	60.31	57.44	60.62
											Example 5	58.42	59.56	61.78	58.74	59.66	60.45	62.45	59.82	59.71	58.79

Table 12: elastic modulus of the skin at the same site in the eighth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	81.56	79.76	76.68	80.54	76.85	77.98	76.37	78.74	77.34	76.46
Example 2	77.84	76.56	76.65	78.88	76.96	77.59	75.12	74.34	76.65	74.34

Example 3	78.45	73.36	75.76	75.37	74.15	76.89	74.81	73.42	75.45	75.64
											Example 4	74.89	73.67	73.85	74.54	73.94	74.61	74.83	72.57	73.45	73.91
Example 5	75.67	72.31	72.98	74.45	73.77	72.91	73.65	71.89	74.57	72.23

Note: the skin elasticity ratio refers to the percentage of the resilience of the skin without negative pressure to the maximum stretching amount with negative pressure, and the larger the skin elasticity percentage value is, the better the skin elasticity is.

From table 11, table 12, it can be seen that the skin elasticity improvement effect is better after the subjects use the whitening aloe gel prepared according to example 1.

7. Firmness of skin

Table 13: skin firmness of the same part in the fourth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	0.403	0.487	0.412	0.456	0.390	0.385	0.424	0.397	0.421	0.439
Example 2	0.456	0.478	0.408	0.416	0.376	0.376	0.387	0.408	0.455	0.436
											Example 3	0.382	0.431	0.410	0.407	0.414	0.416	0.427	0.432	0.365	0.467
Example 4	0.462	0.457	0.387	0.435	0.402	0.365	0.437	0.396	0.501	0.375
											Example 5	0.421	0.455	0.352	0.421	0.367	0.385	0.441	0.505	0.386	0.473

Table 14: skin firmness of the same part in the eighth week

	1	2	3	4	5	6	7	8	9	10
											Example 1	0.210	0.211	0.206	0.216	0.215	0.198	0.216	0.212	0.188	0.217
Example 2	0.235	0.226	0.212	0.232	0.251	0.227	0.226	0.232	0.219	0.223
											Example 3	0.247	0.235	0.230	0.225	0.265	0.229	0.129	0.245	0.226	0.233
Example 4	0.251	0.314	0.250	0.300	0.270	0.291	0.304	0.317	0.312	0.275
											Example 5	0.271	0.295	0.254	0.291	0.261	0.316	0.310	0.292	0.297	0.298

Note: skin firmness refers to the maximum stretching amount of the skin under negative pressure, and the smaller the skin firmness value is, the tighter the skin is.

From table 13, table 14, it can be seen that the skin firmness of the subjects was significantly improved after using the whitening aloe gel prepared according to example 1.

According to the whitening aloe gel, the aloe extract, the purslane extract and the traditional Chinese medicine extracting solution are added, so that multiple effects are mutually cooperated and complemented, the whitening effect is achieved, the purslane extract has good scavenging capacity for oxygen radicals, and has an obvious antioxidation effect, the traditional Chinese medicine extracting solution contains natural whitening, moisturizing and anti-aging components, the skin barrier can be repaired, the water loss is reduced, the skin microcirculation is improved, and the aloe extract is matched with the purslane extract and the traditional Chinese medicine extracting solution, so that the whitening effect is more obvious.

Claims

1. The whitening aloe gel is characterized by comprising the following components in percentage by weight: 60.5% of polyacrylate crosslinked polymer, 1% of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer and SOLLAUM ^TM AX0.3%, polyethylene glycol-752%, 2501Cosmetic Wax 3%, dipropylene glycol 4%, moistshield ^TM 0.05% of eight hyaluronic acid compounds of HA, 0.2% of p-hydroxyacetophenone, 2% of ALISTIN Alistine, 2% of ANTI IRTATION COMPLEX PLUS, 1.2% of triethanolamine, 0.01% of essence, 3% of aloe extract, 2% of purslane extract, 2% of traditional Chinese medicine extracting solution and the balance of deionized water;

the traditional Chinese medicine extracting solution is composed of the following raw materials in percentage by mass: 18 parts of prepared rehmannia root, 20 parts of Chinese yam, 15 parts of poria cocos, 15 parts of rhizoma alismatis, 12 parts of golden cypress, 12 parts of chrysanthemum, 9 parts of moutan bark, 9 parts of cornus officinalis, 9 parts of wolfberry fruit and 9 parts of dried orange peel;

2. The preparation method of the whitening aloe gel according to claim 1, characterized by comprising the following steps:

(2) Weighing a certain amount of SOLAGUM in sequence according to the weight percentage ^TM AX, PEG-75, 2501CosmeticWax, and MoistShield ^TM Adding eight hyaluronic acid compounds of HA into the solution A, carrying out micro-homogenization until the material body rolls, and completely dispersing and dissolving the material to obtain a solution B;

(3) Putting a beaker on a heating device, starting heating and stirring, stopping heating after heating to 85 ℃, then putting the beaker in cold water, cooling to 60 ℃, adding a dipropylene glycol and p-hydroxyacetophenone mixed solution into the solution while stirring, fully and uniformly mixing the solution, then weighing a certain amount of ALISTIN Alistine, ANTI IRRITATION COMPLEXPLUS and triethanolamine according to weight percentage, adding the mixture into the beaker, and uniformly stirring;