CN109498538B

CN109498538B - Composition, cosmetic and essence with moisturizing and whitening effects and preparation method thereof

Info

Publication number: CN109498538B
Application number: CN201811625187.9A
Authority: CN
Inventors: 陈昭武
Original assignee: Guangzhou Baiyun Yanmei Cosmetics Factory
Current assignee: Guangzhou Baiyun Yanmei Cosmetics Factory
Priority date: 2018-12-28
Filing date: 2018-12-28
Publication date: 2021-11-26
Anticipated expiration: 2038-12-28
Also published as: CN109498538A

Abstract

The invention relates to a composition with moisturizing and whitening effects, a cosmetic, an essence and a preparation method thereof, wherein the composition with moisturizing and whitening effects comprises the following raw material components in parts by mass: 1-8 parts of dendrobium stem extract, 1-8 parts of sophora flavescens root extract, 1-10 parts of aloe barbadensis leaf extract and 0.8-6 parts of angelica root extract. The components in the composition with the moisturizing and whitening effects are matched with each other, and the components can fully exert the respective effects by controlling the reasonable dosage of the components, so that the composition with the moisturizing and whitening effects fully exerts good moisturizing and whitening effects.

Description

Composition, cosmetic and essence with moisturizing and whitening effects and preparation method thereof

Technical Field

The invention relates to the field of cosmetics, and particularly relates to a composition, a cosmetic, an essence and a preparation method thereof.

Background

With the continuous improvement of living standard of people, the market demand of cosmetics with the effects of moisturizing, whitening and protecting skin is continuously increased. Conventional moisturizing and whitening cosmetics are classified into moisturizing and whitening cosmetics having a chemically synthesized substance as an active ingredient and moisturizing and whitening cosmetics containing a natural extract as an active ingredient. Among them, the moisturizing and whitening cosmetics containing the chemical synthetic substances have great side effects on human bodies while moisturizing and whitening, and the moisturizing and whitening cosmetics containing the natural extracts have relatively poor moisturizing and whitening effects.

Disclosure of Invention

Based on this, it is necessary to provide a composition, a cosmetic, an essence and a preparation method thereof with good moisturizing and whitening effects, aiming at the problem that the moisturizing and whitening effects of the traditional whitening cosmetics containing natural extracts are relatively poor.

The composition with the effects of moisturizing and whitening comprises the following raw material components in parts by mass:

the components of the composition with the moisturizing and whitening effects are matched with each other, but one is not required. In addition, by controlling the reasonable proportion of the using amount of each component, each component can fully exert respective effect, and the composition with the moisturizing and whitening effects can fully exert good moisturizing and whitening effects.

In one embodiment, at least one of an extract of wolfberry fruit, an extract of echinacea purpurea, an extract of licorice root, an extract of reed rhizome, an extract of salvia miltiorrhiza root, an extract of dogwood fruit, and an extract of wolfberry root is further included.

In one embodiment, the material comprises the following raw material components in parts by mass:

the invention also provides a cosmetic which comprises the composition with the moisturizing and whitening effects.

The invention also provides essence which comprises the following raw material components in parts by mass:

in one embodiment, the preservative is further comprised in an amount of 0.1 to 0.7 parts by mass.

In one embodiment, the humectant is selected from at least one of sodium hyaluronate crosspolymer, polyglutamic acid, and L-lactic acid.

The invention also provides a preparation method of the essence, which comprises the following steps:

uniformly mixing 0.2-5.5 parts by mass of humectant with 20-90 parts by mass of water to obtain phase A;

adding 1-8 parts by mass of dendrobium stem extract, 1-8 parts by mass of sophora flavescens root extract, 1-10 parts by mass of aloe barbadensis leaf extract and 0.8-6 parts by mass of angelica root extract into the phase A, and uniformly mixing to obtain a phase B;

filtering the phase B, and reserving filtrate to obtain the essence.

In one embodiment, the method further comprises the step of adding a preservative to the phase B and mixing the preservative to the phase B before filtering the phase B.

The cosmetics and the essence containing the composition with the moisturizing and whitening effects have good moisturizing and whitening effects.

Detailed Description

The present invention will be described in detail with reference to the following embodiments in order to make the aforementioned objects, features and advantages of the invention more comprehensible. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

The invention provides a composition with moisturizing and whitening effects, which comprises the following raw material components in parts by mass:

the aloe vera leaf extract is rich in polysaccharides, vitamins, amino acids and trace elements, which are components of the natural skin moisturizing factor NMF. The polysaccharide component in the aloe vera leaf extract has a significant moisturizing effect on the skin by hydrating and locking water. The moisture retention mechanism is mainly that polysaccharide contains a large number of polar groups such as hydroxyl, carboxyl and the like, and can form hydrogen bonds with water molecules to bond and lock water, and polysaccharide molecular chains are mutually interwoven into a net, so that the polysaccharide has a strong water locking effect. In addition, the polysaccharide has good film forming property, can form a layer of uniform film, reduces the water evaporation of epidermis, and can induce the stratum corneum to be further hydrated when water is dispersed to the stratum corneum from the basal tissue, so as to preserve the water of the skin and achieve the skin moistening effect. In addition, the polysaccharide, the endogenous polysaccharide component in the skin extracellular matrix and the fibrous protein form an extracellular colloidal matrix, and the matrix contains a large amount of water and can provide water for the skin so as to achieve the effect of deeply replenishing water.

The extract of the sophora flavescens ait root is mainly derived from the root of the sophora flavescens ait, can promote metabolism and activity of keratinocytes, and has the effect of shrinking pores, so that the effect of astringing and locking water is achieved, and water loss is prevented. In addition, the active ingredient matrine contained in the sophora flavescens root extract has the effects of resisting bacteria and diminishing inflammation.

The dendrobium stem extract can promote the expression of AQP3 of cell aquaporin, break through the whole transmembrane protein channel, and facilitate nutrient substances of all components in the composition to enter the stratum corneum of the skin without barriers. In addition, the dendrobium stem extract also has various pharmacological effects, such as the effects of enhancing the immunity of the organism, resisting oxidation and aging, reducing blood sugar, supplementing fluid, promoting the production of body fluid, promoting blood circulation and tonifying qi, fundamentally regulating the functions of the human body, improving the sub-health state of the human body and whitening the skin. In addition, the dendrobium stem extract is rich in nutrient substances such as polysaccharide, dendrobine, free amino acid, vitamin A, vitamin C, vitamin E and the like, and can supplement nutrition for the skin, improve the skin elasticity, moisturize the skin and increase the resistance of the skin to the external adverse environment.

Wherein, the angelica has the functions of anti-inflammation, scavenging oxygen free radicals, enhancing immunity and the like. Research shows that the angelica root extract can inhibit the activity of tyrosinase, block the oxidation path of the melanin generated by the tyrosine, reduce the generation of the melanin and achieve the effect of whitening the skin. In addition, the radix Angelicae sinensis extract also has effects of enhancing skin epidermal water content and cell SOD activity.

In one embodiment, the composition having moisturizing and whitening effects further comprises at least one of a lycium barbarum fruit extract, a echinacea purpurea extract, a licorice root extract, a reed root extract, a salvia miltiorrhiza root extract, a dogwood fruit extract, and a lycium barbarum root extract. Preferably, the composition having moisturizing and whitening effects further comprises a combination of lycium barbarum fruit extract, echinacea purpurea extract, licorice root extract, reed rhizome extract, salvia miltiorrhiza root extract, dogwood fruit extract and lycium barbarum root extract. Further improving the moisturizing and whitening effects of the composition with the moisturizing and whitening effects. Wherein the fructus Lycii and root of fructus Lycii are preferably Ningxia fructus Lycii and Ningxia root of fructus Lycii.

In one embodiment, the composition with the moisturizing and whitening effects comprises the following raw material components in parts by mass:

it should be noted that the sources of the components of the composition with moisturizing and whitening effects are all purchased from santong ford biotechnology limited.

The invention also provides a cosmetic.

A cosmetic comprising the composition having moisturizing and whitening effects of the present invention.

The cosmetic has good moisturizing and whitening effects.

It can be understood that the cosmetics of the present invention can be various products such as lotion, essence, skin cream, moisturizing cream, etc., and are not described herein in any greater detail.

in one embodiment, the essence comprises the following components in parts by mass:

in one embodiment, the essence further comprises 0.1-0.7 parts by mass of a preservative. Furthermore, the preservative is the combination of caprylyl hydroximic acid and 1.3-propylene glycol, and the combination of caprylyl hydroximic acid and 1.3-propylene glycol does not contain a bactericide and traditional preservative components, but has a good effect of inhibiting bacteria and fungi (containing mold), broad-spectrum antibiosis, no need of matching with traditional preservatives, mild property, no stimulation to skin and no hot and pungent feeling after use. In addition, the preservative consisting of the caprylyl hydroximic acid and the 1, 3-propylene glycol has good water solubility, safety, mildness, high efficiency and good compatibility, and is an ideal substitute of the traditional preservative. In addition, the 1, 3-propylene glycol also has the moisturizing effect, and can endow the skin with smooth, fine and moist use feeling after being used. Further, 0.1 to 0.4 part by mass of caprylhydroxamic acid and 0.1 to 0.3 part by mass of 1.3-propanediol are used.

In one embodiment, the humectant is selected from at least one of sodium hyaluronate crosspolymer, polyglutamic acid, and L-lactic acid. Furthermore, experiments prove that the humectant can exert the optimal moisturizing effect when being the combination of the sodium hyaluronate cross-linked polymer, the polyglutamic acid and the L-lactic acid. Further, 0.01 to 0.2 part by mass of a sodium hyaluronate cross-linked polymer, 0.01 to 0.2 part by mass of polyglutamic acid, and 0.2 to 5 parts by mass of L-lactic acid.

L-lactic acid is naturally present in the human body, and it is also a Natural Moisturizing Factor (NMF) and helps to keep moisture in the skin.

The sodium hyaluronate cross-linked polymer belongs to a skin moisturizer, is an acidic mucopolysaccharide, naturally exists in corneal skin, can absorb 1000 times of water by weight of the corneal skin, so as to achieve the purposes of keeping skin moisture, preventing water from losing through epidermis, ensuring that the skin does not feel dry after being used and increasing luster by repairing barriers when the skin is damaged, can improve skin nutrition metabolism, enables the skin to be soft and smooth, removes wrinkles, increases elasticity and prevents aging, and is a good transdermal absorption promoter while keeping moisture. The composition can be used in combination with other nutritional ingredients of the composition with moisturizing and whitening effects, and has effect of promoting nutrient absorption.

The polyglutamic acid has excellent moisturizing performance, can enhance the skin elasticity, mildly inhibits the tyrosine kinase activity, has comprehensive and deep certification on the safety and efficacy, is safe in source, is an edible raw material, and greatly improves the skin elasticity after long-term testing.

It can be understood that the essence of the invention can be uniformly coated on a mask substrate to prepare a mask.

The essence comprises the composition with the moisturizing and whitening effects, and the essence has good moisturizing and whitening effects.

The invention also provides a preparation method of the essence.

A preparation method of essence comprises the following steps:

(1) mixing 0.2-5.5 parts by mass of humectant with 20-90 parts by mass of water to obtain phase A.

(2) Adding 1-8 parts by mass of dendrobium stem extract, 1-8 parts by mass of sophora flavescens root extract, 1-10 parts by mass of aloe barbadensis leaf extract and 0.8-6 parts by mass of angelica root extract into the phase A, and uniformly mixing to obtain a phase B.

(3) Filtering the phase B, and reserving filtrate to obtain the essence.

In one embodiment, the water is deionized water without impurities.

In one embodiment, the preparation method of the essence comprises the following steps: adding 0.05 part of polyglutamic acid, 0.05 part of sodium hyaluronate cross-linked polymer, 2 parts of L-lactic acid and 40 parts of deionized water into a stirring pot together by mass, stirring for 30-40min at 60-65 r/min to obtain phase A, then adding 1-8 parts by mass of dendrobium stem extract, 1-8 parts by mass of sophora flavescens root extract, 1-10 parts by mass of aloe barbadensis leaf extract and 0.8-6 parts by mass of angelica root extract into the phase A, stirring at 60 r/min for 50-60min to disperse uniformly to obtain phase B, adding 0.3 part of caprylyl hydroximic acid and 0.2 part of 1.3-propylene glycol, stirring at 60-65 r/min for 50-60min, stopping stirring, standing for 30-40min, filtering with a 500-mesh filter screen, and retaining the filtrate to obtain the essence.

The preparation method of the essence is simple, and the prepared essence has good moisturizing and whitening effects.

In order that the objects and advantages of the invention will be more clearly understood, the invention is further described in detail below with reference to examples. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

Example 1

A preparation method of essence comprises the following steps:

adding 0.05 part of polyglutamic acid, 2 parts of L-lactic acid and 40 parts of deionized water into a stirring pot together by mass, stirring for 30min at 60 revolutions per minute to obtain a phase A, then adding the components of the composition with the moisturizing and whitening effects in the table 1 into the phase A, stirring for 50min at 60 revolutions per minute until the components are uniformly dispersed to obtain a phase B, then adding 0.3 part of caprylyl hydroximic acid and 0.2 part of 1.3-propylene glycol, continuously stirring for 50min at 60 revolutions per minute, stopping stirring, standing for 30min, filtering through a 500-mesh filter screen, and then retaining a filtrate to obtain the essence.

TABLE 1

Name of raw materials	Content (in)
		Dendrobium stem extract	2
Sophora flavescens root extract	1
		Aloe barbadensis leaf extract	1.5
Angelica root extract	1

Example 2

A preparation method of essence comprises the following steps:

adding 0.05 part of polyglutamic acid, 2 parts of L-lactic acid and 40 parts of deionized water into a stirring pot together by mass, stirring for 30min at 60 revolutions per minute to obtain a phase A, then adding the components of the composition with the moisturizing and whitening effects in the table 2 into the phase A, stirring for 50min at 60 revolutions per minute until the components are uniformly dispersed to obtain a phase B, then adding 0.3 part of caprylyl hydroximic acid and 0.2 part of 1.3-propylene glycol, continuously stirring for 50min at 60 revolutions per minute, stopping stirring, standing for 30min, filtering through a 500-mesh filter screen, and then retaining a filtrate to obtain the essence.

TABLE 2

Name of raw materials	Content (in)
		Dendrobium stem extract	7
Sophora flavescens root extract	6
		Aloe barbadensis leaf extract	5
Angelica root extract	6

Example 3

A preparation method of essence comprises the following steps:

adding 0.05 part of polyglutamic acid, 0.05 part of sodium hyaluronate cross-linked polymer, 2 parts of L-lactic acid and 40 parts of deionized water into a stirring pot together, stirring for 30min at 60 revolutions per minute to obtain a phase A, adding the components of the composition with the moisturizing and whitening effects in the table 3 into the phase A, stirring for 50min at 60 revolutions per minute until the components are uniformly dispersed to obtain a phase B, adding 0.3 part of caprylyl hydroximic acid and 0.2 part of 1.3-propylene glycol, continuously stirring for 50min at 60 revolutions per minute, stopping stirring, standing for 30min, filtering through a 500-mesh filter screen, and retaining a filtrate to obtain the essence.

TABLE 3

Example 4

A preparation method of essence comprises the following steps:

adding 0.05 part of polyglutamic acid, 0.05 part of sodium hyaluronate cross-linked polymer, 2 parts of L-lactic acid and 40 parts of deionized water into a stirring pot together, stirring for 30min at 60 revolutions per minute to obtain a phase A, adding the components of the composition with the moisturizing and whitening effects shown in the table 4 into the phase A, stirring for 50min at 60 revolutions per minute until the components are uniformly dispersed to obtain a phase B, adding 0.3 part of caprylyl hydroximic acid and 0.2 part of 1.3-propylene glycol, continuously stirring for 50min at 60 revolutions per minute, stopping stirring, standing for 30min, filtering through a 500-mesh filter screen, and retaining a filtrate to obtain the essence.

TABLE 4

Name of raw materials	Content (in)
		Dendrobium stem extract	5
Sophora flavescens root extract	6
		Aloe barbadensis leaf extract	5
Angelica root extract	4
		Ningxia wolfberry fruit extract	3
Echinacea purpurea extract	4
		Licorice root extract	3
Reed root extract	3

Example 5

A preparation method of essence comprises the following steps:

adding 0.05 part of polyglutamic acid, 0.05 part of sodium hyaluronate cross-linked polymer, 2 parts of L-lactic acid and 40 parts of deionized water into a stirring pot together, stirring for 30min at 60 revolutions per minute to obtain a phase A, adding the components of the composition with the moisturizing and whitening effects in the table 5 into the phase A, stirring for 50min at 60 revolutions per minute until the components are uniformly dispersed to obtain a phase B, adding 0.3 part of caprylyl hydroximic acid and 0.2 part of 1.3-propylene glycol, continuously stirring for 50min at 60 revolutions per minute, stopping stirring, standing for 30min, filtering through a 500-mesh filter screen, and retaining a filtrate to obtain the essence.

TABLE 5

Name of raw materials	Content (in)
		Dendrobium stem extract	5
Sophora flavescens root extract	6
		Aloe barbadensis leaf extract	5
Angelica root extract	4
		Ningxia wolfberry fruit extract	3
Echinacea purpurea extract	4
		Licorice root extract	3
Reed root is carriedFetching article	3
		Salvia miltiorrhiza root extract	3
Extract of dogwood fruit	3.5
		Ningxia wolfberry root extract	2.5

Comparative example 1

A method of preparing an essence, the steps of which are substantially the same as in example 1, except that: the components of the composition with the moisturizing and whitening effects do not contain dendrobium stem extract.

Comparative example 2

A method for preparing essence, which comprises the steps substantially the same as those of example 1, except that the composition having the moisturizing and whitening effects does not contain the extract of the sophora flavescens ait roots.

Comparative example 3

A method for preparing an essence, which substantially comprises the same steps as in example 1, except that the composition having moisturizing and whitening effects does not contain aloe vera leaf extract.

Comparative example 4

The commercially available natural moisturizing and whitening essence with certain brand comprises 2 parts of pullulan, 3 parts of aloe juice, 10 parts of glycerin and 5 parts of sophora flavescens extracts.

Comparative example 5

A method for preparing essence, which has substantially the same steps as in example 1, except that the components of the composition having moisturizing and whitening effects are different, as shown in table 6 below:

TABLE 6

Performance testing

Test of whitening effectiveness

The inhibition of tyrosinase activity by the essences prepared in examples 1-5 and comparative examples 1-5 was examined in this test.

1. Test method

Referring to section 2.3 of whitening effectiveness test method of in vitro experimental study on skin aging resistance and whitening efficacy of angelica sinensis extract in the 21 st volume of 2010, 4 th of the journal Shizhen national medicine.

1. Evaluation of Effect

The tyrosinase inhibition results are shown in table 7.

TABLE 7

Group of	Tyrosinase inhibition (%)
		Example 1	22.6
Example 2	22.7
		Example 3	24.6
Example 4	29.9
		Example 5	32.6
Comparative example 1	15.2
		Comparative example 2	17.2
Comparative example 3	16.3
		Comparative example 4	13.5
Comparative example 5	12.2

As can be seen from table 7, in the tyrosinase inhibition rate test, the inhibition degree of tyrosinase was significantly better in the example group than in the comparative example group, and the tyrosinase inhibition rate was the highest in the example 5 group, mainly because the whitening efficacy of the composition with moisturizing and whitening efficacy was further improved by the inclusion of the lycium barbarum fruit extract, the echinacea purpurea extract, the licorice root extract, and the like in addition to the conventional composition with moisturizing and whitening efficacy in the example 5 group. The essential liquids in comparative examples 1 to 3 have poor inhibition degrees on tyrosinase mainly because the comparative examples lack important components in the composition with moisturizing and whitening effects, the comparative example 1 lacks dendrobium stem extract, the comparative example 2 lacks sophora flavescens root extract, the comparative example 3 lacks aloe barbadensis leaf extract, and the comparative example 4 is commercially available moisturizing and whitening essential liquid of a certain brand, which has main components different from those of the composition with moisturizing and whitening effects in the embodiments of the present application and has poor whitening effects, and the formula components of the essential liquid of the present application are obtained by a large number of experimental screening by an inventor and can not be randomly combined to bring the tyrosinase inhibition rate as high as 20% or more in table 7 of the present invention. Comparative example 5 although the four effective ingredients of the composition having moisturizing and whitening effects of the present invention were included, the ratio of the four ingredients was not listed in the formulation of the composition having whitening effects of the present invention. The above results indicate that the composition with moisturizing and whitening effects of the present invention has the advantages that the components are not available, and the composition can exert the maximum effect only by being mixed in a reasonable ratio, so as to obtain the optimal whitening effect.

Test of moisturizing Effect

Test samples: the essence of examples 1-5 and comparative examples 1-5 of the invention.

Subject: for women of 25 to 44 years old, the eligible subjects were divided into 10 groups on average, and 30 subjects in each group corresponded to the groups of examples 1 to 5 of the present invention and the groups of comparative examples 1 to 5.

The tested part: marking three tested parts on the inner sides of the two forearms, and randomly distributing the tested parts into a sample painting area 1, a sample painting area 2 and a sample painting area 3, wherein the sample painting area is used for painting each group of essence.

Smearing area of 3cm × 3cm, smearing dosage: 2mg/cm²。

The testing steps are as follows: see QB/T4256 + 2011 guide for evaluation of moisturizing efficacy of cosmetics.

And (3) testing results: the results of the sample application zone tests are shown in Table 8.

TABLE 8

Note: the application area 1 is the water content of stratum corneum of the skin 1 hour after application of the test substance (T1).

The application area 2 is the water content of the stratum corneum of the skin 4 hours after application of the test substance (T2).

The application area 3 is the water content of the stratum corneum of the skin 8 hours after the application of the test substance (T3).

The subjects in each of the examples had higher water content in the stratum corneum than in the comparative examples under the test conditions of 1 hour after application, 4 hours after application, and 8 hours after application. Further, after 1 hour, 4 hours, and 8 hours after the application, there was a significant difference in the moisture content of example 1 compared to comparative example 1, comparative example 2, comparative example 3, comparative example 4, and comparative example 5. Further, as can be seen from Table 8, the skin stratum corneum of the subjects in the example group showed no significant decrease in water content even after 8 hours of application. The above results indicate that the composition with moisturizing and whitening effects of the present invention has the advantages that the components are not available, and the composition can exert the effects to the maximum extent only by being mixed in a reasonable ratio, so as to obtain the optimal moisturizing effect.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. The essence is characterized by comprising the following raw material components in parts by mass:

2. the method for preparing the essence according to claim 1, comprising the steps of:

adding 0.05 part of polyglutamic acid, 0.05 part of sodium hyaluronate cross-linked polymer, 2 parts of L-lactic acid and 40 parts of deionized water into a stirring pot, stirring for 30min at 60 revolutions per minute to obtain phase A, then adding each extract into the phase A, stirring for 50min at 60 revolutions per minute until the extracts are uniformly dispersed to obtain phase B, then adding 0.3 part of caprylyl hydroximic acid and 0.2 part of 1.3-propylene glycol, continuously stirring for 50min at 60 revolutions per minute, stopping stirring, standing for 30min, filtering through a 500-mesh filter screen, and retaining filtrate to obtain the essence.