CN111450031A

CN111450031A - Freeze-dried nanofiber invisible mask and preparation method thereof

Info

Publication number: CN111450031A
Application number: CN202010347228.3A
Authority: CN
Inventors: 刘科勇
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-04-28
Filing date: 2020-04-28
Publication date: 2020-07-28

Abstract

The invention discloses a freeze-dried nanofiber invisible mask and a preparation method thereof, wherein the freeze-dried nanofiber invisible mask comprises mask active ingredients and a mask base material, and the mask active ingredients comprise the following raw materials in parts by weight: 0.1-30 parts of collagen, 0.1-30 parts of plant extract, 1-50 parts of hyaluronic acid, 0.1-10 parts of peptide, 1-20 parts of sturgeon caviar extract, 1-20 parts of fucus extract, 0.1-5 parts of superoxide dismutase and 0-100 parts of water. The mask disclosed by the invention has the functions of whitening, nourishing, moisturizing, resisting oxidation, removing wrinkles and the like, the mask base material is very thin and is almost in a transparent state when being applied, and the obvious white, milky white, black or other color traces of a common mask are not generated.

Description

Freeze-dried nanofiber invisible mask and preparation method thereof

Technical Field

The invention relates to the technical field of skin care products, in particular to a freeze-dried nanofiber invisible mask and a preparation method thereof.

Background

The facial mask is characterized in that the face is covered with the essence within a short time, so that the external air and pollution are temporarily isolated, the nutrient content on the surface of the skin is improved, pores of the skin are expanded, the secretion and metabolism of sweat glands are promoted, the oxygen content of the skin is increased, the skin is favorable for removing products of metabolism of epidermal cells and accumulated grease substances, and on the other hand, the moisture in the facial mask permeates into the cuticle of the epidermis, so that the skin becomes soft, and is naturally bright and elastic. The facial mask mainly has four types, namely a paste type, a tearing type, a jelly type and a wet tissue type. The mud paste type facial mask is commonly an alga facial mask, a mud facial mask and the like, the most common tear-off facial mask is a special nasal paste for blackheads, the jelly type is popular with a sleep facial mask, and the wet tissue type is generally a facial mask paper which is packaged in a single piece and is soaked with facial mask essence. Later appearing facial masks made of silk belong to the wet tissue type facial masks.

The plant extract, such as bitter orange, is rich in vitamin C, natural vitamin P and carotene, and has effects of increasing body resistance, increasing capillary elasticity, inhibiting formation of carcinogen, softening and protecting blood vessel, promoting blood circulation, and reducing cholesterol and blood lipid. Grapefruit (known under the name Citrus paradisi Macf.) is a plant of the genus Citrus of the family rutaceae that is rich in vitamin C, various isoflavones and flavones, as well as coumarins, furocoumarins and limonoids. Therefore, the grapefruit is a natural antioxidant, can eliminate fatigue, promote the generation of antibodies, beautify skin, enhance the functions of skin and pores, and is beneficial to the health care and beauty of the skin, and meanwhile, has the effects of clearing heat and annealing, and is beneficial to the improvement of the permeability and fragility of blood vessels.

The determinant of skin aging is the destruction of collagen in the dermal layer by the internal or external environment. Collagen accounts for about 70% of the skin, and collagen accounts for about 80% of the dermis, and the three-dimensional spiral structure of the collagen can lock deep moisture of the skin, so that the skin is glossy, moist and tender. Collagen supports the skin like a spring in the skin, and when a rupture occurs, the dermal tissue collapses, wrinkles appear, and the skin relaxes and sags. Whitening and moisturizing are always pursued in the field of cosmetics, and the moisturizing effect is an important condition for ensuring the health of skin and delaying aging. As people age, the skin moisturizing mechanisms are damaged, the water content between skin tissue cells and cells is reduced, and when the water content of the stratum corneum is reduced to below 10%, the skin becomes dry, loses elasticity, wrinkles and accelerates skin aging. On the other hand, the skin is affected by heat, cold, wind, detergent, ultraviolet radiation, etc., and the top layer becomes drier. The cosmetics on the market at present often contain a sealing agent, a moisture absorbent, a hydrophilic matrix, a light-proofing agent and some special additive ingredients. However, these ingredients are relatively irritating, and especially most cosmetics are preserved for a long period of time by adding a preservative, which causes permanent damage to the skin. Even the whitening mask on the market at present contains heavy metal elements such as lead and mercury, and the whitening purpose is achieved temporarily, but the whitening mask can cause serious damage to human bodies. Therefore, the selection of safe and effective whitening and moisturizing masks is very important. In addition, the mask on the market at present often appears white, milk white, black or other colors when being applied and used, and is difficult to avoid unnatural feeling or embarrassing atmosphere when facing other people, so a mask product which is transparent when being applied and used is needed, and the situation which is repulsive is avoided.

Disclosure of Invention

In view of the problems in the prior art, an object of the present invention is to provide a freeze-dried nanofiber invisible mask.

The invention also aims to provide a preparation method of the freeze-dried nanofiber invisible mask.

Further, the invention also aims to provide a using method of the freeze-dried nanofiber invisible mask.

The invention adopts the following technical scheme:

the freeze-dried nanofiber invisible mask comprises mask active ingredients and a mask base material, wherein the mask active ingredients comprise the following raw materials in parts by weight:

optionally, the mask active ingredients comprise the following raw materials:

further, the mask base material comprises a nanofiber layer made of Thermoplastic Polyurethane (TPU) by electrospinning, and the thickness of the individual nanofiber layers is 100nm to 1000nm, such as 100nm, 200nm, 300nm, 400nm, 500nm, 600nm, 700nm, 800nm, 900nm, 1000 nm.

Furthermore, the electrostatic spinning parameters are set to be spinning distance of 1-10 mm, voltage of 2.5-8.5 KV, liquid supply rate of 0.001-0.05 m L/min, the thermoplastic polyurethane is made into a nanofiber layer by the electrostatic spinning technology, and the mask base material can be formed by laminating a plurality of (for example, 2, 3, 4 and the like) nanofibers.

Collagen is the main component in skin, and accounts for more than 72% of the protein content in skin cells. The skin luster depends on the water content, and the collagen has good water retention capacity, so that the skin is moist, glossy and healthy. Specifically, the collagen has similarity with the structure of the skin stratum corneum, so that the collagen has good affinity and compatibility with the skin, can permeate into the epidermis layer of the skin, can form a skin membrane, protects the skin, moistens and softens the skin, and promotes the fine shrinkage of pores; and combines with water in the horny layer to form a net structure, locks water, is absorbed by the skin, plays a role of natural moisturizing factors, makes the skin plump, stretches wrinkles and effectively prevents aging.

Further, the collagen is 0.1 to 30 parts, for example, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29 or 30 parts.

Further, the plant extract comprises at least one of a wintergreen extract, a boswellia extract, a tea tree extract, an origanum majorana extract, a bitter orange extract, a eucalyptus extract, a patchouli extract, a lemon extract, a sandalwood extract, a chamomile extract, a bergamot extract, a grapefruit extract, a rose extract, an osmanthus fragrans extract, a clove extract, a jasmine extract, a rosemary extract, a lavender extract, a mint extract, a avocado extract, a centella extract, and a agave extract.

The term "plant extract" as used herein is a volatile aromatic substance extracted from parts of plants such as leaves, flowers, seeds, fruits, roots, barks, resins, hearts, etc. by steam distillation, extrusion, cold dipping, liposuction, solvent extraction, etc., and has high concentration of aroma and volatility.

Further, the holly extract is a ilex purpurea thunb leaf extract. The term "wintergreen" as used herein is of the genus gaultheria of ericaceae. The ilex extract can improve skin blood microcirculation, relieve dryness, improve spirit and improve perception.

The term "boswellia extract" as used herein is extracted from boswellia resin, and emits a mild, pure woody aroma, but also a bland fruity aroma, which can be relaxed and relaxed never before.

Furthermore, the tea tree extract is tea tree extract, the main chemical components are terpineol, limonene, eucalyptol, balol and anisic, and the tea tree extract has the effects of sterilizing and diminishing inflammation, astringing pores, treating common cold, cough, rhinitis and asthma, improving dysmenorrheal, irregular menstruation, genital infection and the like. It is suitable for oily and acne skin, and can be used for treating suppurative wound, burn, sunburn, tinea pedis, and dandruff.

Further, the marjoram extract can relieve pain caused by mental diseases, increase perspiration function, remove water retention of tissues, help to lose weight, and relieve anxiety and stress.

Further, the bitter orange extract includes at least one of a bitter orange flower extract and a bitter orange leaf extract. The bitter orange flower has the functions of purifying, astringing, resisting inflammation, resisting bacteria, relieving, resisting oxidation, scavenging free radicals, whitening and balancing skin. The bitter orange leaf extract is extracted from bitter orange leaves and twigs, has the functions of regulating skin, relieving sebum secretion, cleaning greasy skin, stimulating brain to consciously accept knowledge, and has good relaxing effect, so that fast beating heart can be gently removed, and sleep can be facilitated.

The term "free radical" as used herein refers to an atom or group with an unpaired electron formed by homolytic cleavage of a covalent bond, including, but not limited to, the following: superoxide anion radical (O)₂ ^-) Hydrogen peroxide (H)₂O₂) Hydroxyl radical (. OH), monooxygen (C) ((II))¹O₂) Carbon-centered (CH-R) lipid radicals or L radicals, and the like free radicals in the human body are very active atoms or groups that can oxidize other substances in the human body.

Further, the eucalyptus extract is a eucalyptus leaf extract. The term "eucalyptus" as used herein is eucalyptus, a plant of the family myrtaceae, genus eucalyptus. The Eucalyptus globulus extract has obvious effects on skin scald, can prevent bacterial breeding and pus accumulation, promote the construction of new skin tissues, improve the purulent, herpes and whelk skins, and dredge pores; can also be used for treating incised wound, ulcer and inflammation, and has effects of refreshing brain and concentrating attention. The California leaf extract can be administered to relieve muscular soreness and improve blood circulation.

Further, the patchouli extract can promote cell renewal, balance the central nervous system, and improve the problems of rough skin, acne, skin inflammation, athlete's foot, scalp fat leakage, eczema, and the like.

After the lemon extract is added into the product, the product can be applied to a human body to realize local weight loss, remove redundant ponding and fat and thin the face.

Furthermore, the rosemary extract has strong astringency, can condition greasy and dirty skin, promote blood circulation, stimulate hair regeneration, relieve skin congestion, edema and swelling, relieve dysmenorrhea, promote urination and reduce weight.

The lignum Santali albi extract has effects of improving skin aging, dryness and water deficiency, removing scar and fine lines, moistening skin, preventing wrinkle, soothing nervous tension and anxiety, and relaxing people.

Further, the bergamot extract is a bergamot fruit extract. The term "bergamot" as used herein is of the genus citrus, rutaceae. The bergamot extract has obvious antibacterial effect, and can be used for treating eczema, psoriasis, acne, scabies, varicosis, wound, herpes, and seborrheic dermatitis of skin and scalp; is especially beneficial to oily skin, can balance sebaceous gland secretion of oily skin, and can remarkably improve the health state of the skin when being used together with the Eucalyptus extract.

Further, the grapefruit extract is a grapefruit peel extract. The grapefruit extract is obtained by squeezing grapefruit pericarp, and has fresh and sweet smell. The grapefruit extract has effects of nourishing skin tissue cells, increasing physical strength, helping oily skin keep clean, relieving bronchitis, promoting urination, improving obesity, edema and lymph gland system diseases, and resisting infection. The grapefruit extract can also be used for relieving depression, especially depression or drowsiness in winter, and refreshing, and is used as regulator of seasonal mental disorder to stimulate mood, and relieve stress and depression.

Furthermore, the rose extract contains various plant proteins and tannins, is fragrant and sweet in smell, has the characteristics of smoothness, quietness and soothing, is strong in moisture-retaining capacity, and also has certain whitening and anti-aging effects. In addition, the rose extract is the mildest bactericide and astringent, can enhance skin luster, quickly supplement moisture, enhance skin vitality, tighten skin, eliminate wrinkles and relieve emotion.

The term "avocado extract" as used herein is rich in vitamins and vegetable oils, and has moisturizing, exfoliating, and sunscreen effects. In addition, the skin care product is rich in unsaturated fatty acid and vitamin, active ingredients of the skin care product can deeply nourish the skin, strengthen the moisture retention of the skin, and is rich in sterol, so that the skin care product can help to produce more skin collagen, soften the skin and lighten color spots. Vitamin E contained in the avocado extract is an antioxidant, and can effectively relieve skin, prevent aging, prevent the generation of wrinkles in advance and delay the aging speed of the skin. These rich nutrients can meet the requirements of various skin types, such as dry skin: has good moisture retention and water locking effects, and is helpful for restoring the sebum membrane of the skin on the surface layer and keeping moisture; sensitive muscle: can play the roles of relieving, repairing and enhancing the skin barrier; mature skin: has the effect of firming the skin, especially the care to the skin around the eyes, and can also effectively maintain the skin structure, resist aging and prevent wrinkles from growing early.

The term "centella asiatica extract" as used herein is mainly composed of asiaticoside and madecassoside, centella asiatica (CENTE LL A ASIATICA) extract can tighten the junction between epidermis and dermis, can soften skin, helps promote the formation of collagen in dermis, and has the effect of tightening skin.

Specifically, the centella asiatica extract has the effects of resisting oxidation, inhibiting free radical activity, regulating skin balance, lightening pigmentation and refreshing skin, can effectively remove redundant free radicals in vivo and protect human cell tissues from being oxidized and damaged by the free radicals. Asiaticoside, the main component of centella asiatica, has the effect of promoting the activity of scar fibroblast, so that the asiaticoside has the effect of removing scars, has good polymerization effect with phospholipid substances, can be used for eliminating whelk, has the effect of inhibiting glucuronidase, can inhibit bacteria and promote the activity of cells.

The term "agave" as used herein is a perennial evergreen large herb of the genus agave of the family asparagiceae. The Agave americana extract has effect in inhibiting hyaluronidase, effectively inhibiting decomposition of hyaluronic acid, and moisturizing skin, and can be added into product to increase water content of horny layer after being applied to skin, and can be used as skin-activating anti-wrinkle agent, allergy inhibitor, slimming agent and antiinflammatory agent.

Further, the plant extract is 0.1-30 parts, such as 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29 or 30 parts.

Further, the hyaluronic acid comprises small molecule hyaluronic acid and/or ultra-small molecule hyaluronic acid.

Further, the molecular weight of the small molecule hyaluronic acid is 200000-1000000 daltons, optionally 200000-400000 daltons, 400000-600000 daltons, 600000-800000 daltons, 800000-1000000 daltons.

Further, the molecular weight of the ultra-small hyaluronic acid is 3000-100000 daltons, optionally 3000-8000 daltons, 8000-10000 daltons, 10000-20000 daltons, 20000-40000 daltons, 40000-60000 daltons, 60000-80000 daltons, 80000-100000 daltons.

In this context, the paste formed by emulsifying hyaluronic acid and oil phase is uniform and fine, and has stable emulsifying effect. Furthermore, hyaluronic acid is an ideal natural moisturizing factor, is a main component of intercellular matrix, can increase the water content of skin, and has the effects of protecting skin, repairing skin barrier and recovering skin physiological function. In view of poor skin permeability of macromolecular hyaluronic acid, hyaluronic acid of the present application preferably includes small molecular hyaluronic acid and ultra-small molecular hyaluronic acid. The small molecular hyaluronic acid has good permeability, and can penetrate into dermis to increase skin water content. The ultra-small molecular hyaluronic acid can carry other active ingredients to permeate into dermis, so that the active ingredients exert the maximum effect. Meanwhile, the hyaluronic acid with small and ultra-small molecular weight can exert the best effect.

Further, the hyaluronic acid is 1-50 parts, for example 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49 or 50 parts.

Further, the peptide is 0.1-10 parts, such as 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10 parts. Peptides belong to oligopeptides and are easily absorbed.

Further, the peptide comprises at least one of a dipeptide, a tripeptide, a tetrapeptide, a pentapeptide, a hexapeptide, a heptapeptide, an octapeptide and a nonapeptide.

In the application, the components of the peptides have adaptive effects, specifically, in various embodiments, the second peptide has the effects of resisting wrinkles, promoting absorption and utilization of collagen and relaxing muscles, the third peptide can stimulate generation of glucosamine polyacid and collagen and promote growth of skin cells and wound healing and proliferation, the fourth peptide has the effects of resisting edema, improving microcirculation, strengthening blood circulation and eliminating inflammation, the fifth peptide can directly act on a dermis layer to promote proliferation of collagen, elastic fibers and hyaluronic acid, achieve the aim of tightening the skin, improve the moisture content of the skin, and can accelerate the effect of tightening and pulling by matching with other moisture-retaining components, the sixth peptide can inhibit excessive release of nerve substances, influence the action of transfer proteins between subcutaneous nerves and muscles, reduce the generation of dynamic lines, wrinkles and the like, the seventh peptide can relax the muscles, achieve the effects of smoothing dynamic lines, static lines and fine lines, the eighth peptide can promote the proliferation of collagen, elastic fibers and the hyaluronic acid, increase the thickness of the skin, reduce the generation of melanin-induced melanin lines, reduce the melanin-induced breakdown, and reduce the melanin-induced melanin-derived melanin-induced cell-induced breakdown-induced melanin-induced skin receptor.

The term "sturgeon caviar extract" as used herein is an extract of roe of sturgeon, is a collagen enhancer and protein crosslinking inhibitor, and improves cell mitochondrial function, and it is rich in vitamins and minerals, and can nourish skin and reduce aging. In addition, it can relieve the symptoms of skin aging, including skin roughness, fine lines, wrinkles, sagging and hyperpigmentation, i.e., skin darkening, while it has the effect of keeping the skin moist. The sturgeon caviar extract in the present application, in conjunction with other ingredients, may improve mitochondrial function and thus help improve skin appearance at the cellular level and alleviate inflammatory symptoms around aging skin tissue cells.

Further, the sturgeon caviar extract is 1-20 parts, such as 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 or 20 parts.

The term "Fucus vesiculosus extract" as used herein is a brown alga grown on a rock on the shore, which has a dark brown alga body, is bifurcated, is a flat angular leaf, contains fucoidan sulfate, and is effective in scavenging superoxide anion radicals and hydroxyl radicals. The Fucus vesiculosus extract is prepared from Fucus vesiculosus in rock coast and saline-alkali beach of northern temperate zone. The Fucus vesiculosus extract can balance metabolism, improve immunity, supplement mineral substances, absorb arsenic, form metallothionein containing arsenic in cells, is rich in calcium element and iodine element, has effects of caring skin, delaying aging, moistening skin, whitening skin, removing speckle, and repairing damaged skin, and makes skin refreshing, smooth, bright and beautiful.

Further, the fucus extract accounts for 1-20 parts, such as 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 or 20 parts.

As used herein, the term "Superoxide Dismutase" (SOD), alternative name liver protein, oryzanol protein, which includes copper-and zinc-containing Superoxide Dismutase (Cu-Zn-SOD), manganese-containing Superoxide Dismutase (Mn-SOD), iron-containing Superoxide Dismutase (Fe-SOD), and the like. The source of the superoxide dismutase is not limited to animals and plants, but is not limited to superoxide dismutase, recombinant superoxide dismutase, modified superoxide dismutase and derivatives showing the activity of the superoxide dismutase. Can eliminate free radical and lipid peroxide in mammary duct, activate atrophic mammary cell, and promote microcirculation. Superoxide dismutase can stimulate the absorption of collagen, inhibit collagen breakage, effectively stabilize fibrous protein in mammary tissue, and promote the balance development of mammary tissue.

Superoxide dismutase is commercially available, and considering that there may be some differences in enzyme activity between different producers and between different lots, the enzyme activity of superoxide dismutase is, as an example, 100 to 1000 international units/mg (U/mg), such as about 100, 200, 300, 400, 500, 600, 700, 800, 900, 1000U/mg.

Further, the superoxide dismutase accounts for 0.1-5 parts, such as 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 2, 3, 4 or 5 parts.

Further, the water may be distilled water, deionized water, ultrapure water, or the like, with deionized water being preferred. The amount of water is 0 to 100 parts, for example 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 60, 70, 80, 90 or 100 parts.

The raw materials used in the present invention are generally commercially available unless otherwise specified.

In various embodiments, the mask or mask fluid of the present application is free of preservatives, such as, by way of example: benzoic acid and salts thereof, sorbic acid and salts thereof, dehydroacetic acid and salts thereof, parabens, and the like, and specifically, for example, methylparaben, propylparaben, phenoxyethanol, benzyl alcohol, phenethyl alcohol, bis (hydroxymethyl) imidazolidinyl urea, potassium sorbate, sodium benzoate, chlorphenesin, sodium dehydroacetate, and the like.

Further, the mask pack or mask solution is free of dioxane, silicone oil (dimethicone), sodium lauryl sulfate, sodium laureth sulfate, sodium trideceth sulfate, ammonium lauryl sulfate, ammonium laureth sulfate, styrene-acrylamide copolymer, diethanolamide cocoate, monoethanolamide cocoate, olive cetearyl oleate, polysorbate-60, polysorbate-80, sorbitan olive oleate, methylgluco sesquistearate, PEG-20 methylgluco sesquistearate, PEG-40 hydrogenated castor oil, PPG-26-butanolether-26, PEG-4 polyglycerol-2 stearate, PEG-60 hydrogenated castor oil, steareth-2, steareth-21, stearyl alcohol ether-40, and mixtures thereof, PPG-13-decyltetradecyltetraeth-24, cetearyl glucoside, PEG-100 stearate, glyceryl stearate, cocoyl glucoside, ceteareth-25, PEG-40 stearate, glyceryl stearate citrate, polyglyceryl-3-methylglucose distearate, polyglyceryl-10 stearate, polyglyceryl-10 myristate, polyglyceryl-10 dioleate, polyglyceryl-10 laurate, polyglyceryl-10 isostearate, polyglyceryl-10 oleate, polyglyceryl-10 diisostearate, polyglyceryl-6 laurate, polyglyceryl-6 myristate, sucrose stearate, sucrose polystearate, and the like.

In various embodiments, a method for preparing a freeze-dried nanofiber invisible mask comprises the following steps:

(A) preparing active ingredients of the facial mask: uniformly mixing collagen, plant extract, hyaluronic acid, peptide, sturgeon caviar extract, Fucus vesiculosus extract, superoxide dismutase and water to obtain active ingredients of the facial mask;

(B) coating or soaking the active ingredients of the facial mask on a facial mask substrate;

(C) pre-freezing: freeze-drying the facial mask base material with facial mask active ingredients at-20 deg.C to-30 deg.C for 2-5 h under vacuum degree of 5-50 Pa (for example, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 30, 32, 35, 38, 42, 45, 48, 50Pa), removing water, and vacuum packaging.

In certain embodiments, a method of using a lyophilized nanofiber invisible mask, comprising the steps of:

(a) wetting the mask with 10-40 ml of water;

(b) and applying the moistened facial mask to the face for 10-30 minutes.

The moisture in the mask is removed by a freeze drying technology, and the rest of the nutritional skin care essence is remained in the mask base material, so that the mask base material is a nanofiber layer with a very thin thickness, and is almost in a transparent state after a user wets the mask with water, and the obvious marks of white, milky white, black or other colors of a common mask are avoided, so that the mask has a more scientific and technological sense and is more fashionable in use visual effect, and can be favored by young users.

The storage method of the product of the present application: storing in dry and cool environment. Is suitable for the crowd: any skin type.

And (4) inspecting the prepared mask, enabling the product to be qualified, discharging, performing spot inspection to be qualified, and warehousing.

As used herein, "and/or" includes any and all combinations of one or more of the associated listed items. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.

Unless defined otherwise, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the relevant art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.

The exemplary invention described herein may suitably lack any one or more of the element limitations, which are not specifically disclosed herein. Thus, the terms "comprising," "including," "containing," and the like are to be construed broadly and in a non-limiting sense. Furthermore, the terms used herein are used as terms of description and not of limitation, and there is no intention in the use of such terms to describe only some of their characteristics but, in the light of the claims, various modifications are possible within the scope of the invention. Thus, while the present invention has been particularly disclosed in terms of preferred embodiments and optional features, modification of the invention herein disclosed to embody it may be noted by those skilled in the art, and such modifications and variations are considered to be within the scope of the invention.

Compared with the prior art, the invention has the beneficial effects that:

(1) the facial mask disclosed by the invention has the functions of whitening, nourishing, moisturizing, resisting oxidation, removing wrinkles and the like, the base material of the facial mask is very thin, the facial mask is almost in a transparent state when being applied, the obvious white, milky white, black or other color traces of a common facial mask are avoided, and the facial mask is very beneficial for small molecular hyaluronic acid and other solution-state molecular essence to permeate into the deep layer of skin;

(2) the mask disclosed by the invention has no bad irritation in the using process, is mild and comfortable, has the capabilities of continuously whitening and moisturizing, and is fresh and not greasy.

Detailed Description

For better explanation of the present invention, the following specific examples are further illustrated, but the present invention is not limited to the specific examples.

Example 1

the plant extract is prepared from the following components in a mass ratio of 1: 1: 0.5: 0.5 parts of ilex extract, eucalyptus extract, bergamot extract, grapefruit extract. The hyaluronic acid is micromolecular hyaluronic acid with the molecular weight of 200000-400000 daltons. The mass ratio of the peptides is 1: 1 and five peptides.

The preparation method of the freeze-dried nanofiber invisible mask comprises the following steps:

(B) coating or soaking a facial mask substrate with a facial mask active component, wherein the facial mask substrate is a single-layer nanofiber layer with the thickness of 800 nm;

(C) pre-freezing: freeze-drying the mask base material with the mask active ingredients at-30 ℃ for 4-5 h, wherein the vacuum degree is 40 Pa.

Example 2

the plant extract is prepared from the following components in a mass ratio of 2: 1: 2: 0.5 of bitter orange extract, Eucalyptus extract, grapefruit extract, rosemary extract. The hyaluronic acid is micromolecular hyaluronic acid (20 parts) with the molecular weight of 400000-600000 daltons and ultra-micromolecular hyaluronic acid (10 parts) with the molecular weight of 3000-10000 daltons. The mass ratio of the peptides is 1: 1 and hexapeptides.

The preparation method of the mask was the same as in example 1.

Example 3

the plant extract is prepared from the following components in a mass ratio of 1: 1: 1: 0.5: 0.5: 0.5 of ilex extract, tea tree extract, bitter orange extract, eucalyptus extract, bergamot extract, grapefruit extract. The hyaluronic acid is micromolecular hyaluronic acid with the molecular weight of 600000-1000000 daltons. The mass ratio of the peptides is 1: 2, and heptapeptide.

The preparation method of the mask was the same as in example 1.

Example 4

the plant extract is prepared from the following components in a mass ratio of 1: 1: 1: 1: 0.5: 0.5 of tea tree extract, bitter orange extract, eucalyptus extract, bergamot extract, rose extract, rosemary extract. The hyaluronic acid is micromolecular hyaluronic acid with the molecular weight of 400000-1000000 daltons. The mass ratio of the peptides is 1: 2: 2, a tetrapeptide, a heptapeptide and an octapeptide.

The preparation method of the mask was the same as in example 1.

Comparative example 1

The ingredients of comparative example 1 did not contain plant extracts, peptides, and the rest was the same as example 2.

Comparative example 2

The hyaluronic acid in the components of comparative example 2 was all high molecular weight hyaluronic acid, and the rest was the same as in example 2.

Comparative example 3

The mask of comparative example 3 was a mask base material made of a general nonwoven fabric, and the rest was the same as in example 2.

And (3) evaluating the product effect: human body application test

1. The test method comprises the following steps: volunteers 210 (female, age 18-30 years), health: the skin of the subject is healthy, has no allergic history of the skin disease, and meets the voluntary selection standard of the subject. The facial masks of examples 1 to 4 and comparative examples 1 to 3 were used for each group of 30 persons, which were randomly divided into 7 groups based on the parallel control principle. After cleaning the face of the test volunteer in the morning and evening, 1 piece of the finished facial mask is respectively applied to the face, and the skin moisture change and the melanin change are tested 3 times each time after the test volunteer is used for 30 days and is stopped for 15 days, and the average value is taken.

2. A detection instrument:

a skin tester (korean EHANG, EH-990U) for detecting moisture change and melanin change of the skin.

3. The experimental result standard is as follows:

the effect is shown: the water content is 40-50%, and the melanin value is lower than 20;

the method has the following advantages: the water content is 20-30%, and the melanin value is 20-30%;

and (4) invalidation: the water content is less than 20%, and the melanin value is more than 30%.

Table 1: results of the volunteer skin whitening and moisturizing test (human).

As can be seen from table 1, examples 1 to 4 of the present invention have significant moisturizing and whitening effects, and compared with the masks of comparative examples 1 to 3, the whitening effects of examples 1 to 4 were still significant after being used for 15 days after 30 days, while the whitening effect of the volunteers who used the masks of comparative examples 1 to 3 was significantly reduced, indicating that the masks of the present invention have more durable whitening effects.

The above description is only exemplary of the present invention and is not intended to limit the scope of the present invention, which is defined by the claims appended hereto, as well as the appended claims.

Claims

1. The freeze-dried nanofiber invisible mask comprises mask active ingredients and a mask base material, and is characterized in that the mask active ingredients comprise the following raw materials in parts by weight:

2. the freeze-dried nanofiber invisible mask as claimed in claim 1, wherein the mask base material comprises a nanofiber layer, the nanofiber layer is made of thermoplastic polyurethane through electrostatic spinning, and the thickness of a single nanofiber layer is 100 nm-1000 nm.

3. The freeze-dried nanofiber invisible mask as claimed in claim 2, wherein the electrostatic spinning parameters are set to spinning distance of 1-10 mm, voltage of 2.5-8.5 KV and liquid supply rate of 0.001-0.05 m L/min.

4. The lyophilized nanofiber facial mask as claimed in claim 1, wherein the plant extract comprises at least one of ilex extract, boswellia extract, camellia sinensis extract, marjoram extract, bitter orange extract, eucalyptus extract, pogostemon cablin extract, lemon extract, sandalwood extract, chamomile extract, bergamot extract, grapefruit extract, rose extract, osmanthus fragrans extract, clove extract, jasmine extract, rosemary extract, lavender extract, mint extract, avocado extract, centella asiatica extract, and agave extract.

5. The lyophilized nanofiber invisible mask as claimed in claim 1, wherein the hyaluronic acid comprises small molecule hyaluronic acid and/or ultra-small molecule hyaluronic acid.

6. The freeze-dried nanofiber invisible mask as claimed in claim 5, wherein the molecular weight of the small molecular hyaluronic acid is 200000-1000000 daltons; the molecular weight of the ultra-small molecular hyaluronic acid is 3000-100000 daltons.

7. The lyophilized nanofiber invisible mask as claimed in claim 1, wherein the peptides comprise at least one of peptides selected from the group consisting of dipeptide, tripeptide, tetrapeptide, pentapeptide, hexapeptide, heptapeptide, octapeptide and nonapeptide.

8. The lyophilized nanofiber facial mask as claimed in claim 1, wherein the facial mask contains no preservative.

9. The preparation method of the freeze-dried nanofiber invisible mask as claimed in any one of claims 1-8, which is characterized by comprising the following steps:

(C) pre-freezing: freeze-drying the mask base material with the mask active ingredients at-20 ℃ to-30 ℃ for 2-5 h, wherein the vacuum degree is 5-50 Pa.

10. The use method of the freeze-dried nanofiber invisible mask as claimed in any one of claims 1 to 8, characterized by comprising the following steps:

(a) wetting the mask with 10-40 ml of water;

(b) and applying the moistened facial mask to the face for 10-30 minutes.