CN110613663A - Skin repairing composition, skin care product and preparation method thereof - Google Patents

Skin repairing composition, skin care product and preparation method thereof Download PDF

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Publication number
CN110613663A
CN110613663A CN201911020476.0A CN201911020476A CN110613663A CN 110613663 A CN110613663 A CN 110613663A CN 201911020476 A CN201911020476 A CN 201911020476A CN 110613663 A CN110613663 A CN 110613663A
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extract
skin
skin care
care product
composition
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钟鸣
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Zhejiang Lanshu Cosmetics Co Ltd
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Zhejiang Lanshu Cosmetics Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/75Anti-irritant

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
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  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a skin repairing composition, a skin care product and a preparation method thereof, wherein the skin repairing composition comprises the following components: houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract and American ginseng extract; the weight ratio of the houttuynia cordata extract to the pseudo-ginseng extract to the ganoderma atrum extract to the polygonatum odoratum extract to the American ginseng extract is (0.3-3): (0.1-1): (0.1-1): (0.1-1): (0.1 to 1). The skin repairing composition and the skin care product containing the skin repairing composition have the effects of moisturizing, sterilizing, resisting inflammation, resisting allergy, repairing, enhancing the autoimmunity of the skin, resisting aging and the like, and the skin repairing liquid product is mild, safe and non-toxic and is suitable for various skins.

Description

Skin repairing composition, skin care product and preparation method thereof
Technical Field
The invention relates to the technical field of cosmetics, and particularly relates to a skin repairing composition, a skin care product and a preparation method thereof.
Background
With the development of science and technology and the improvement of the living standard of people in recent years, a plurality of animal and plant active ingredients with skin beautifying and protecting functions in the nature are discovered by human beings, are widely applied to the fields of cosmetics and skin care products, and continuously develop new functional skin care products to achieve better skin beautifying and protecting effects.
Most of the existing cosmetics and skin care products have single effect, a large amount of chemical substances harmful to human bodies are added for increasing the effect, especially anti-inflammatory and repairing cosmetics and skin care products, and limited or forbidden chemical substances such as medicament-containing hormones and the like are added, and the harmful substances can cause serious injury to the human bodies after long-term use.
Disclosure of Invention
In view of the above, the present invention aims to provide a skin repairing composition, a skin care product and a preparation method thereof, which have the effects of moisturizing, continuously preserving moisture, sterilizing, resisting inflammation, resisting allergy, repairing, enhancing skin immunity, skin elasticity, resisting aging, etc., are safe and non-toxic, and are suitable for various skin types.
In order to achieve the above purpose, the invention provides the following technical scheme:
a skin rejuvenation composition comprising: houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract and American ginseng extract; the weight ratio of the houttuynia cordata extract to the pseudo-ginseng extract to the ganoderma atrum extract to the polygonatum odoratum extract to the American ginseng extract is (0.3-3): (0.1-1): (0.1-1): (0.1-1): (0.1 to 1).
As a further improvement of the above technical solution, said skin rejuvenation composition further comprises dipotassium glycyrrhizinate; preferably, the mass ratio of the dipotassium glycyrrhizinate to the houttuynia cordata extract is (1-5): (1-10).
As a further improvement of the above technical solution, the skin rejuvenation composition further comprises allantoin; preferably, the mass ratio of the allantoin to the houttuynia cordata extract is (1-3): (1-10).
A skin care product containing the skin repairing composition is provided.
As a further improvement of the above technical scheme, the raw materials of the skin care product further comprise: solvents, humectants, chelating agents, preservatives, fragrances, and solubilizers.
As a further improvement of the technical scheme, the skin care product comprises the following raw materials in parts by weight: 2-8 parts of a skin repairing composition, 78-95 parts of a solvent, 3-10 parts of a humectant, 0.05-0.2 part of a chelating agent, 0.3-1 part of a preservative, 0.01-0.1 part of an aromatic and 0.05-0.15 part of a solubilizer.
As a further improvement of the technical scheme, the solvent is water.
As a further improvement of the technical scheme, the humectant comprises one or more of butanediol, propylene glycol, glyceryl polyether-26, ethylhexyl glycerin and sodium hyaluronate.
As a further improvement of the technical scheme, the chelating agent comprises one or two of disodium EDTA and tetrasodium EDTA.
As a further improvement of the technical scheme, the preservative comprises one or two of phenoxyethanol and methylparaben.
As a further improvement of the above technical scheme, the aromatic comprises essence and/or plant essential oil.
As a further improvement of the technical scheme, the solubilizer comprises one or more of PEG-40 hydrogenated castor oil, PEG-20 hydrogenated castor oil and polysorbate-20.
The preparation method of the skin care product comprises the following steps: the raw materials are mixed and stirred evenly under the closed condition.
As a further improvement of the above technical scheme, the raw materials of the skin care product further comprise: solvents, humectants, chelating agents, preservatives, fragrances, and solubilizers; the preparation method comprises the following steps:
firstly, heating a solvent, a humectant and a chelating agent to 80-85 ℃ under a closed condition while stirring, and uniformly mixing to obtain a first mixing agent;
cooling the first mixture to 40-45 ℃ under stirring in a closed condition, adding the skin repair composition and the preservative, cooling to 35-38 ℃ under stirring in a closed condition, adding the solubilizer and the aromatic, and uniformly stirring in a closed condition; obtaining a second mixture;
the resulting second mixture was filtered.
As a further improvement of the above technical solution, the preparation method of the skin care product further comprises: and sterilizing the first mixture at the constant temperature of 80-85 ℃ for 15-40 min.
As a further improvement of the above technical solution, the preparation method further comprises: the stirring speed is 15-35 r/min.
The invention has the beneficial effects that:
(1) the synergistic interaction effect among the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract and the American ginseng extract is utilized, so that the obtained skin repairing composition and the skin care product containing the skin repairing composition have the effects of moisturizing, sterilizing, resisting inflammation, resisting allergy, repairing, enhancing the self-immunity and the elasticity of the skin, resisting aging and the like, and the skin repairing liquid is mild, safe, non-toxic, non-irritant and suitable for various skin types.
(2) The skin care product disclosed by the invention is simple in preparation method, low in preparation cost, wide in market prospect and suitable for large-scale production.
In order to make the aforementioned and other objects, features and advantages of the invention more comprehensible, preferred embodiments accompanied with figures are described in detail below.
Detailed Description
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention.
This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, but rather should be construed as broadly as the present invention is capable of modification in various respects, all without departing from the spirit and scope of the present invention.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.
The terms as used herein:
"prepared from … …" is synonymous with "comprising". The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.
The conjunction "consisting of … …" excludes any unspecified elements, steps or components. If used in a claim, the phrase is intended to claim as closed, meaning that it does not contain materials other than those described, except for the conventional impurities associated therewith. When the phrase "consisting of … …" appears in a clause of the subject matter of the claims rather than immediately after the subject matter, it defines only the elements described in the clause; other elements are not excluded from the claims as a whole.
When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when the range "1 ~ 5" is disclosed, the ranges described should be construed to include the ranges "1 ~ 4", "1 ~ 3", "1 ~ 2 and 4 ~ 5", "1 ~ 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.
"and/or" is used to indicate that one or both of the illustrated conditions may occur, e.g., a and/or B includes (a and B) and (a or B).
A skin rejuvenation composition comprising: houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract and American ginseng extract; the weight ratio of the houttuynia cordata extract to the pseudo-ginseng extract to the ganoderma atrum extract to the polygonatum odoratum extract to the American ginseng extract is (0.3-3): (0.1-1): (0.1-1): (0.1-1): (0.1 to 1);
in addition, the above extract: refers to a solution obtained by soaking or mixing a substance of an extract to be obtained in a solvent for extraction. The extraction process can be carried out with the aid of the selection of suitable solvents, such as: water, ethanol/water mixture, and extracting by separation, percolation, decoction, countercurrent extraction, ultrasonic extraction, microwave extraction, and supercritical fluid extraction, wherein the extract can be further evaporated and concentrated to obtain extract and dried extract.
The herba Houttuyniae extract contains volatile oil, African bean glycoside, hyperoside and houttuynia cordata alkali; the essential components of the volatile oil comprise decanoyl acetaldehyde, methyl n-nonanone, myrcene and sunflower aldehyde; the flavone components comprise quercetin, rutin, etc., wherein the content of decanoyl acetaldehyde is the highest; decanoyl acetaldehyde is houttuynine sodium bisulfite, and modern pharmacological tests prove that the houttuynine sodium bisulfite has the functions of antibiosis, antivirus, anti-inflammation, antianaphylaxis, antitumor, diuresis and enhancing the immunity of the organism. The houttuynia cordata has obvious inhibiting effect on streptococcus, staphylococcus aureus, bacillus influenzae, catacoccus and pneumococcus; it also has therapeutic effect on Escherichia coli, dysentery bacillus, and typhoid bacillus.
The Notoginseng radix extract contains Notoginseng radix saponin R1, ginsenoside Rg1, ginsenoside Rc, ginsenoside Rb1 and ginsenoside Rd, and has effects of resisting inflammation, improving microcirculation, removing wrinkle and speckle, scavenging oxygen free radical, increasing oxygen saturation of skin tissue, and increasing skin activity.
The ganoderma atrum extract contains ganoderma triterpenes, polysaccharide, protein, amino acid, adenine, steroid saponin and trace element effective components, has obvious SOD activity, and can obviously remove free radicals generated by organisms, thereby preventing the free radicals from damaging the organisms, preventing lipid peroxidation, protecting cells, delaying cell aging, and comprehensively playing the roles of oxidation resistance, aging resistance and bacteriostasis.
The rhizoma Polygonati Odorati extract is derived from rhizome of Polygonatum odoratum of Liliaceae, and has effects of keeping moisture and resisting aging.
The American ginseng extract contains various saponins and polysaccharides, can promote skin blood circulation, increase skin nutrition, regulate water-oil balance of skin, prevent skin dehydration, sclerosis and wrinkling, and the active substances can also enhance skin elasticity to regenerate cells. In particular, the saponin contained in the American ginseng extract has the effects of resisting oxidation, delaying senility and inhibiting bacteria, and can eliminate acne marks and make skin white, tender and glossy.
Commercially available houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract and American ginseng extract are adopted in the application. Through a large amount of researches, the inventor of the application finds that the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract and the American ginseng extract are compounded as raw materials, the raw materials have good synergistic effects, and the obtained skin repairing composition has remarkable effects of moisturizing, continuously moisturizing, sterilizing, resisting inflammation, resisting allergy, repairing, enhancing the skin immunity, the skin elasticity, resisting aging and the like. The proportion of the raw materials is obtained by a large amount of research and statistical analysis of the inventor, and the raw materials can play a good synergistic effect in the dosage range and simultaneously do not generate any side effect.
Preferably, the raw materials of the skin rejuvenation composition further include dipotassium glycyrrhizinate; the ratio of the dipotassium glycyrrhizinate to the houttuynia cordata extract is (1-5): (1-10).
The dipotassium glycyrrhizinate not only has the functions of resisting allergy, inflammation, oxidation and bacteria, but also can effectively remove superoxide ions and hydroxyl free radicals, obviously inhibit liposome peroxide, promote epithelial cell tissue regeneration, activate skin self-repair energy and the like; the research of the inventor finds that the skin repairing composition has good compatibility with the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract and the American ginseng extract, and can enhance the absorption of the skin to active ingredients in the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract and the American ginseng extract to enhance the effect, so that the obtained skin repairing composition has better effects of sterilization, anti-inflammation and anti-allergy repairing, and does not generate side effects.
Preferably, the raw material of the skin rejuvenation composition further comprises allantoin; the ratio of the allantoin to the houttuynia cordata extract is (1-3): (1-10).
Allantoin is an amphoteric compound, can combine with multiple substances to form double salt, has effects of protecting from light, sterilizing, relieving pain, resisting oxidation, and keeping skin moisture, moistening and softening. The inventor of the application finds that the further addition of allantoin can further enhance the effects of protecting skin tissues, preventing skin moisture from diffusing, sterilizing and the like, clear necrotic tissues, stimulate the growth of new healthy tissues, proliferate cells, contribute to the self-improvement of skin, relieve discomfort and skin irritation reaction of other cosmetic additives such as surfactants, eliminate allergic phenomena such as skin redness, roughness, erythra and the like, and achieve the effect of repairing skin.
A skin care product containing the skin repairing composition is provided. The skin care product can be skin care cream, eye cream, facial mask, facial cleanser, smoothing toner or essence and the like.
Optionally, the raw materials of the skin care product further comprise: solvents, humectants, chelating agents, preservatives, fragrances, and solubilizers.
Further, the skin care product comprises the following raw materials in parts by weight:
2-8 parts of skin repairing composition, such as 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts or 8 parts;
78-95 parts of solvent, such as 78 parts, 80 parts, 83 parts, 85 parts, 88 parts, 90 parts, 92 parts or 95 parts;
3-10 parts of humectant, such as 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts;
0.05-0.2 parts of chelating agent, such as 0.05 part, 0.08 part, 0.1 part, 0.12 part, 0.15 part, 0.18 part or 0.2 part;
0.3-1 part of preservative, such as 0.3 part, 0.4 part, 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part or 1 part and the like;
0.01 to 0.1 part of aromatic, such as 0.01 part, 0.03 part, 0.05 part, 0.08 part or 0.1 part and the like;
0.05-0.15 part of solubilizer, such as 0.05 part, 0.08 part, 0.1 part, 0.12 part or 0.15 part.
Optionally, the solvent is water, preferably pure water or deionized water, so that the shelf life of the obtained skin care product is longer.
Optionally, the moisturizer comprises one or more of butylene glycol, propylene glycol, glyceryl polyether-26, ethylhexyl glycerin, and sodium hyaluronate.
Optionally, the chelating agent comprises one or both of disodium EDTA and tetrasodium EDTA.
Optionally, the preservative comprises one or both of phenoxyethanol and methylparaben.
Optionally, the fragrance comprises a perfume and/or a plant essential oil.
The essence is preferably natural plant essence, and has little or even no irritation to skin; of course, other artificially synthesized essences can also be used. The plant essential oil is volatile aromatic substance extracted from flower, leaf, stem, root or fruit of plant by steam distillation, extrusion, cold soaking or solvent extraction. The plant essential oil can be jasmine essential oil, rose essential oil, orchid essential oil or lavender essential oil.
Optionally, the solubilizer comprises one or more of PEG-40 hydrogenated castor oil, PEG-20 hydrogenated castor oil and polysorbate-20.
The preparation method of the skin care product comprises the following steps: the raw materials are mixed and stirred evenly under the closed condition.
Preferably, the preparation method comprises:
firstly, heating a solvent, a humectant and a chelating agent to 80-85 ℃ under a closed condition while stirring, and uniformly mixing to obtain a first mixing agent;
cooling the first mixture to 40-45 ℃ under stirring in a closed condition, adding the skin repair composition and the preservative, cooling to 35-38 ℃ under stirring in a closed condition, adding the solubilizer and the aromatic, and uniformly stirring in a closed condition; obtaining a second mixture;
the resulting second mixture was filtered.
Preferably, the preparation method further comprises: and sterilizing the first mixture at the constant temperature of 80-85 ℃ for 15-40 min.
The obtained first mixture is sterilized at the constant temperature of 80-85 ℃ for 15-40 min, so that the effective period of the finally obtained skin care product can be effectively prolonged.
Optionally, the preparation method further comprises: the stirring speed is 15-35 r/min.
Preferably, the preparation method further comprises: the filtered second mixture was allowed to stand between stills to ensure product consistency.
The synergistic interaction effect among the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract and the American ginseng extract is utilized, so that the obtained skin repairing composition and the skin care product containing the skin repairing composition have the effects of moisturizing, sterilizing, resisting inflammation, resisting allergy, repairing, enhancing the self-immunity and the elasticity of the skin, resisting aging and the like, and the skin repairing liquid is mild, safe and nontoxic and is suitable for various skins.
In order to facilitate understanding of the present invention, embodiments of the present invention will be described in detail below with reference to specific examples, but those skilled in the art will appreciate that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
Example 1
The skin care composition of the embodiment comprises houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract and American ginseng extract, wherein the mass ratio of the houttuynia cordata extract to the pseudo-ginseng extract to the ganoderma atrum extract to the polygonatum odoratum extract to the American ginseng extract is 0.3: 0.5: 1: 1: 1.
the skin care product of the embodiment comprises the following raw materials in parts by weight: 78 parts of solvent, 10 parts of humectant, 3 parts of the skin care composition of the embodiment, 1 part of preservative, 0.2 part of chelating agent, 0.15 part of solubilizer and 0.1 part of aromatic; wherein the solvent is deionized water, and the humectant is butanediol, propylene glycol and glyceryl polyether-26 in a weight ratio of 1: 1: 1, the preservative is methyl hydroxybenzoate, the chelating agent is disodium EDTA, the aromatic is orchid essential oil, and the solubilizer is PEG-40 hydrogenated castor oil.
The preparation method of the skin care product of the embodiment comprises the following steps:
(1) sterilizing the container in advance and then washing the container clean by using sterile water;
(2) adding a solvent, a humectant and a chelating agent into a container, stirring at a stirring speed of 15r/min and heating to 80 ℃ under a closed condition to completely and uniformly mix the solvent, the humectant and the chelating agent to obtain a first mixture, and then keeping the first mixture at 80 ℃ for constant-temperature sterilization for 40 min;
(3) stirring the sterilized first mixture at a stirring speed of 25r/min and cooling to 45 ℃ under a closed condition; then adding the skin repairing composition and the preservative, and cooling to 37 ℃ under the closed condition while stirring at the stirring speed of 25 r/min; adding a solubilizer and an aromatic, and uniformly stirring at a stirring speed of 25r/min under a closed condition to obtain a second mixing agent;
(4) filtering with clean and sterilized 200 mesh filter screen, sampling, inspecting, and packaging.
Example 2
The skin care composition of the embodiment comprises houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract and American ginseng extract, wherein the mass ratio of the houttuynia cordata extract to the pseudo-ginseng extract to the ganoderma atrum extract to the polygonatum odoratum extract to the American ginseng extract is 1.5: 0.8: 0.5: 0.5: 0.5.
the skin care product of the embodiment comprises the following raw materials in parts by weight: 85 parts of solvent, 6 parts of humectant, 5 parts of the skin care composition of the embodiment, 0.6 part of preservative, 0.12 part of chelating agent, 0.1 part of solubilizer and 0.05 part of aromatic; wherein the solvent is deionized water, and the humectant is butanediol, propylene glycol, glyceryl polyether-26, ethylhexyl glycerin and sodium hyaluronate according to a weight ratio of 1: 1: 1: 0.5: 1, the preservative is phenoxyethanol and methylparaben in a weight ratio of 1: 1, the chelating agent is disodium EDTA, the aromatic is orchid essential oil, and the solubilizer is PEG-40 hydrogenated castor oil.
The preparation method of the skin care product of the embodiment comprises the following steps:
(1) sterilizing the container in advance and then washing the container clean by using sterile water;
(2) adding a solvent, a humectant and a chelating agent into a container, stirring at a stirring speed of 30r/min and heating to 85 ℃ under a closed condition to completely and uniformly mix the solvent, the humectant and the chelating agent to obtain a first mixture, and then keeping the first mixture at 85 ℃ for constant-temperature sterilization for 20 min;
(3) stirring the sterilized first mixture at a stirring speed of 30r/min and cooling to 45 ℃ under a closed condition; then adding the skin repairing composition and the preservative, and cooling to 37 ℃ under the closed condition while stirring at the stirring speed of 30 r/min; adding a solubilizer and an aromatic, and uniformly stirring at a stirring speed of 30r/min under a closed condition to obtain a second mixing agent;
(4) filtering with clean and sterilized 500-mesh filter screen, sampling, inspecting, and packaging.
Example 3
The skin care composition of the embodiment comprises houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract and American ginseng extract, wherein the mass ratio of the houttuynia cordata extract to the pseudo-ginseng extract to the ganoderma atrum extract to the polygonatum odoratum extract to the American ginseng extract is 3: 0.1: 0.1: 0.1: 0.1.
the skin care product of the embodiment comprises the following raw materials in parts by weight: 92 parts of solvent, 3 parts of humectant, 7 parts of the skin care composition of the embodiment, 0.3 part of preservative, 0.105 part of chelating agent, 0.05 part of solubilizer and 0.01 part of aromatic; wherein the solvent is deionized water, and the humectant is butanediol, propylene glycol and glyceryl polyether-26 in a weight ratio of 1: 1: 0.5, wherein the preservative is phenoxyethanol and methylparaben in a weight ratio of 1: 1, the chelating agent is disodium EDTA, the aromatic is orchid essential oil, and the solubilizer is PEG-40 hydrogenated castor oil.
The preparation method of the skin care product of the embodiment comprises the following steps:
(1) sterilizing the container in advance and then washing the container clean by using sterile water;
(2) adding a solvent, a humectant and a chelating agent into a container, stirring at a stirring speed of 35r/min and heating to 80 ℃ under a closed condition to completely and uniformly mix the solvent, the humectant and the chelating agent to obtain a first mixture, and then keeping the first mixture at 80 ℃ for constant-temperature sterilization for 15 min;
(3) stirring the sterilized first mixture at a stirring speed of 35r/min and cooling to 45 ℃ under a closed condition; then adding the skin repairing composition and the preservative, and cooling to 37 ℃ while stirring at a stirring speed of 35r/min under a closed condition; adding a solubilizer and an aromatic, and uniformly stirring at a stirring speed of 35r/min under a closed condition to obtain a second mixing agent;
(4) filtering with a clean and sterilized 800-mesh filter screen, sampling, inspecting, and packaging after qualification. .
Example 4
The skin care composition of the embodiment comprises houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract, American ginseng extract, dipotassium glycyrrhizinate and allantoin, wherein the mass ratio of the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract, the American ginseng extract, the dipotassium glycyrrhizinate and the allantoin is 3: 1: 1: 1: 1: 1: 1.
the skin care product of the embodiment comprises the following raw materials in parts by weight: 80 parts of solvent, 8 parts of humectant, 4 parts of the skin care composition of the embodiment, 0.8 part of preservative, 0.15 part of chelating agent, 0.12 part of solubilizer and 0.08 part of aromatic; wherein the solvent is deionized water, and the humectant is butanediol, propylene glycol, glyceryl polyether-26, ethylhexyl glycerin and sodium hyaluronate according to a weight ratio of 1: 1: 1: 0.5: 1, the preservative is phenoxyethanol and methylparaben in a weight ratio of 1: 1, the chelating agent is disodium EDTA, the aromatic is orchid essential oil, and the solubilizer is PEG-40 hydrogenated castor oil.
The preparation method of the skin care product of the embodiment comprises the following steps:
(1) sterilizing the container in advance and then washing the container clean by using sterile water;
(2) adding a solvent, a humectant and a chelating agent into a container, stirring at a stirring speed of 25r/min and heating to 80 ℃ under a closed condition to completely and uniformly mix the solvent, the humectant and the chelating agent to obtain a first mixture, and then keeping the first mixture at 80 ℃ for constant-temperature sterilization for 25 min;
(3) stirring the sterilized first mixture at a stirring speed of 25r/min and cooling to 45 ℃ under a closed condition; then adding the skin repairing composition and the preservative, and cooling to 37 ℃ under the closed condition while stirring at the stirring speed of 25 r/min; adding a solubilizer and an aromatic, and uniformly stirring at a stirring speed of 25r/min under a closed condition to obtain a second mixing agent;
(4) filtering with clean and sterilized 1000 mesh filter screen, sampling, inspecting, and packaging.
Example 5
The skin care composition of the embodiment comprises houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract, American ginseng extract, dipotassium glycyrrhizinate and allantoin, wherein the mass ratio of the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract, the American ginseng extract, the dipotassium glycyrrhizinate and the allantoin is 2: 1: 0.5: 0.5: 0.5: 1: 1.
the skin care product of the embodiment comprises the following raw materials in parts by weight: 88 parts of solvent, 5 parts of humectant, 6 parts of the skin care composition of the present example, 0.5 part of preservative, 0.08 part of chelating agent, 0.08 part of solubilizer and 0.03 part of fragrance; wherein the solvent is deionized water, and the humectant is butanediol, propylene glycol, glyceryl polyether-26, ethylhexyl glycerin and sodium hyaluronate according to a weight ratio of 1: 1: 1: 0.5: 1, the preservative is phenoxyethanol and methylparaben in a weight ratio of 1: 1, the chelating agent is disodium EDTA, the aromatic is orchid essential oil, and the solubilizer is PEG-40 hydrogenated castor oil.
The preparation method of the skin care product of the embodiment comprises the following steps:
(1) sterilizing the container in advance and then washing the container clean by using sterile water;
(2) adding a solvent, a humectant and a chelating agent into a container, stirring at a stirring speed of 30r/min and heating to 85 ℃ under a closed condition to completely and uniformly mix the solvent, the humectant and the chelating agent to obtain a first mixture, and then keeping the first mixture at 85 ℃ for constant-temperature sterilization for 30 min;
(3) stirring the sterilized first mixture at a stirring speed of 35r/min and cooling to 40 ℃ under a closed condition; then adding the skin repairing composition and the preservative, and cooling to 37 ℃ under the closed condition while stirring at the stirring speed of 30 r/min; adding a solubilizer and an aromatic, and uniformly stirring at a stirring speed of 30r/min under a closed condition to obtain a second mixing agent;
(4) filtering with clean and sterilized 500-mesh filter screen, sampling, inspecting, and packaging. .
Example 6
The skin care composition of the embodiment comprises houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract, American ginseng extract, dipotassium glycyrrhizinate and allantoin, wherein the mass ratio of the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract, the American ginseng extract, the dipotassium glycyrrhizinate and the allantoin is 3: 1: 1: 1: 1: 1: 1.
the skin care product of the embodiment comprises the following raw materials in parts by weight: 95 parts of solvent, 3 parts of humectant, 8 parts of the skin care composition of the embodiment, 0.3 part of preservative, 0.05 part of chelating agent, 0.05 part of solubilizer and 0.01 part of aromatic; wherein the solvent is deionized water, and the humectant is butanediol, propylene glycol and glyceryl polyether-26 in a weight ratio of 1: 1: 0.5, wherein the preservative is phenoxyethanol and methylparaben in a weight ratio of 1: 1, the chelating agent is disodium EDTA, the aromatic is orchid essential oil, and the solubilizer is PEG-40 hydrogenated castor oil.
The preparation method of the skin care product of the embodiment comprises the following steps:
(1) sterilizing the container in advance and then washing the container clean by using sterile water;
(2) adding a solvent, a humectant and a chelating agent into a container, stirring at a stirring speed of 25r/min and heating to 80 ℃ under a closed condition to completely and uniformly mix the solvent, the humectant and the chelating agent to obtain a first mixture, and then keeping the first mixture at 80 ℃ for constant-temperature sterilization for 25 min;
(3) stirring the sterilized first mixture at a stirring speed of 25r/min and cooling to 40-45 ℃ under a closed condition; then adding the skin repairing composition and the preservative, and cooling to 37 ℃ under the closed condition while stirring at the stirring speed of 25 r/min; adding a solubilizer and an aromatic, and uniformly stirring at a stirring speed of 25r/min under a closed condition to obtain a second mixing agent;
(4) filtering with clean and sterilized 500-mesh filter screen, sampling, inspecting, and packaging.
Comparative example 1
The difference from example 1 is that: the skin rejuvenation composition was prepared by removing the Panax notoginseng extract, as in example 1.
Comparative example 2
The difference from example 1 is that: the same procedure as in example 1 was repeated except that the extract of houttuynia cordata was removed from the skin-rejuvenating composition.
Comparative example 3
The difference from example 1 is that: the skin rejuvenation composition was prepared by removing the Ganoderma atrum extract, as in example 1.
Comparative example 4
The difference from example 1 is that: the same procedure as in example 1 was repeated except that the extract of Yuzhu in the skin care composition was removed.
Comparative example 5
The difference from example 1 is that: the skin rejuvenation composition was prepared as in example 1 except that the American ginseng extract was removed.
Comparative example 6
The difference from example 1 is that: replacing the mass ratio of the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract and the American ginseng extract with 0.1: 1: 1: 1: 1, the same as others
Example 1.
Comparative example 7
The difference from example 1 is that: replacing the mass ratio of the houttuynia cordata extract, the pseudo-ginseng extract, the ganoderma atrum extract, the polygonatum odoratum extract and the American ginseng extract with 3: 0.1: 0.1: 0.1: the other steps are the same as those in example 1.
It is to be noted that the same technical effects can be achieved by replacing the above-mentioned moisturizer, preservative, chelating agent, fragrance and solubilizer with the other compounds described above.
The skin care products obtained in examples 1 to 6 and comparative examples 1 to 7 were measured for their moisturizing effect, anti-inflammatory effect, and anti-allergy repairing effect.
1. Test of moisturizing Effect
14 sets of experiments were performed, and the skin care products obtained in examples 1 to 6 and comparative examples 1 to 7 and pure water were used, respectively, and 25 people in each set were women aged 18 to 45 years.
Before and after 1 hour, 2 hours and 4 hours of smearing, respectively measuring the moisture content (wt%) of different experimental areas of the face of each experimenter by using a skin moisture tester (CBS, CBS-805 model), and taking the average value of each group; the test results are shown in table 1 below.
TABLE 1
2. Anti-inflammatory Effect test
14 groups of experiments are set, the skin care products obtained in the above examples 1-6 and the skin care products obtained in the comparative examples 1-7 and pure water are respectively used, 25 persons in each group are selected from patients with the age of 18-45 years old whose skin is bitten by mosquitoes to cause inflammation, and the anti-inflammatory effect of the patients is observed by naked eyes.
Each group of experimenters applied the corresponding skin care product or pure water twice daily at the same time on the inflamed area, and the anti-inflammatory effect was tested three days later. The skin inflammatory condition was graded on 3 grades: no obvious relief, obvious relief and recovery. The test results are shown in table 2 below.
TABLE 2
3. Anti-allergy repair effect test
14 experiments were conducted, and the skin care products obtained in examples 1 to 6 and comparative examples 1 to 7 and pure water were used, respectively, and women with facial skin inflammation such as desquamation and erythema in the age range of 18 to 45 years old were selected for each group of 25 women.
After each group of experimenters cleans the face in the morning and evening, corresponding skin care products or pure water are smeared, the skin care products or the pure water are massaged until the skin care products or the pure water are absorbed, other products are not used or are used together, and the condition of the face skin of each group of experimenters is observed after one month and three months. When tested, skin condition was graded in 4 grades: excellent (no desquamation, no erythema, smooth and moist skin), good (no desquamation, no erythema), common (slight desquamation, slight erythema) and poor (desquamation, erythema); the test results are shown in table 3 below.
TABLE 3
In conclusion, the skin care product provided by the invention can simultaneously realize good effects of moisturizing, resisting inflammation and resisting allergy and repairing the skin.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.
Furthermore, those skilled in the art will appreciate that while some embodiments herein include some features included in other embodiments, rather than other features, combinations of features of different embodiments are meant to be within the scope of the invention and form different embodiments. For example, in the claims above, any of the claimed embodiments may be used in any combination. The information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person skilled in the art.

Claims (10)

1. A skin rejuvenation composition characterized by: the method comprises the following steps: houttuynia cordata extract, pseudo-ginseng extract, ganoderma atrum extract, polygonatum odoratum extract and American ginseng extract; the weight ratio of the houttuynia cordata extract to the pseudo-ginseng extract to the ganoderma atrum extract to the polygonatum odoratum extract to the American ginseng extract is (0.3-3): (0.1-1): (0.1-1): (0.1-1): (0.1 to 1).
2. The skin rejuvenation composition as defined in claim 1 wherein: the skin rejuvenation composition further comprises dipotassium glycyrrhizinate; preferably, the mass ratio of the dipotassium glycyrrhizinate to the houttuynia cordata extract is (1-5): (1-10).
3. The skin rejuvenation composition as defined in claim 2 wherein: the skin rejuvenation composition further includes allantoin; preferably, the mass ratio of the allantoin to the houttuynia cordata extract is (1-3): (1-10).
4. A skin care product comprising the skin care composition according to any one of claims 1 to 3.
5. A skin care product according to claim 4 wherein: the skin care product also comprises the following raw materials: solvents, humectants, chelating agents, preservatives, fragrances, and solubilizers.
6. A skin care product according to claim 5, characterized in that: the skin care product comprises the following raw materials in parts by weight: 2-8 parts of a skin repairing composition, 78-95 parts of a solvent, 3-10 parts of a humectant, 0.05-0.2 part of a chelating agent, 0.3-1 part of a preservative, 0.01-0.1 part of an aromatic and 0.05-0.15 part of a solubilizer.
7. A skin care product according to claim 5, characterized in that: the solvent is water; the humectant comprises one or more of butanediol, propylene glycol, glyceryl polyether-26, ethylhexyl glycerin and sodium hyaluronate; the chelating agent comprises one or two of disodium EDTA and tetrasodium EDTA; the preservative comprises one or two of phenoxyethanol and methylparaben; the aromatic comprises essence and/or plant essential oil; the solubilizer comprises one or more of PEG-40 hydrogenated castor oil, PEG-20 hydrogenated castor oil and polysorbate-20.
8. A method of preparing a skin care product according to any one of claims 4 to 7, characterized in that: the method comprises the following steps: the raw materials are mixed and stirred evenly under the closed condition.
9. The method for preparing a skin care product according to claim 8, characterized in that: the skin care product also comprises the following raw materials: solvents, humectants, chelating agents, preservatives, fragrances, and solubilizers; the preparation method comprises the following steps:
firstly, heating a solvent, a humectant and a chelating agent to 80-85 ℃ under a closed condition while stirring, and uniformly mixing to obtain a first mixing agent;
cooling the first mixture to 40-45 ℃ under stirring in a closed condition, adding the skin repair composition and the preservative, cooling to 35-38 ℃ under stirring in a closed condition, adding the solubilizer and the aromatic, and uniformly stirring in a closed condition; obtaining a second mixture;
filtering the obtained second mixture;
preferably, the stirring speed is 15-35 r/min.
10. The method for preparing a skin care product according to claim 9, characterized in that: the preparation method further comprises the following steps: and sterilizing the first mixture at the constant temperature of 80-85 ℃ for 15-40 min.
CN201911020476.0A 2019-10-25 2019-10-25 Skin repairing composition, skin care product and preparation method thereof Pending CN110613663A (en)

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Application publication date: 20191227