CN108671176A - A kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash - Google Patents
A kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash Download PDFInfo
- Publication number
- CN108671176A CN108671176A CN201810769188.4A CN201810769188A CN108671176A CN 108671176 A CN108671176 A CN 108671176A CN 201810769188 A CN201810769188 A CN 201810769188A CN 108671176 A CN108671176 A CN 108671176A
- Authority
- CN
- China
- Prior art keywords
- parts
- mixing
- oil
- emulsifying
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash, raw material includes water, vaseline, camellia seed oil, synthetic wax, Chinese gall, 3 diisopstearate of polyglycereol, moutan bark, Asian puccoon, alum, cuttle bone, Radix stemonae japonicae, cloves bud, purslane, centella, sorrel root, menthol, methyl hydroxybenzoate, hexylene glycol, Chlorphenesin, Phenoxyethanol；Preparation method includes the following steps：Oil phase thing mixing extraction, aqueous-phase material mixing extraction, oil phase mixing, water phase mixing, mixing and emulsifying, addition preservative, are mixed evenly rear natural cooling and obtain product.Due to be the external curing diaper rash without hormone constituted using pure natural components plant extract Chinese medicine composition preparation method, the product good effect prepared, Small side effects, easy to use, using effect is more preferable.
Description
Technical field
The present invention relates to tcm fields, and in particular to a kind of plant extract Chinese medicine composition of external curing diaper rash
Preparation method.
Background technology
The red hip of baby are medically also known as " diaper rash " or " diaper rash ", are skin diseases common in baby, hair
The raw finger that diaper position is wrapped up in baby betides the limitation sheet erythema at baby' diaper packing position or the illness of unboiled water bubble, is
A kind of dermal inflammatory lesion.For the common scytitis of ewborn infant, the mostly body because of children's blood-head, skin and flesh is delicate, wet diaper
Too long, dampness and heat is handed over steams dipping, and skin buttocks of falling into oblivion is caused to form.Skin of buttock is moist for a long time, sultry, the thorn in excrement and urine
Sharp substance can make skin damage and occur that small hip are rubescent, and secondary infection but will on damaged skin for the microorganisms such as bacterium, fungi
Aggravate the degree of red hip；Skin of buttock is also an induced factor often in contact with some cleaning solutions.Nurse it is improper can be serious
Skin infection and damage are affected to the life of baby.Traditional method is to smear vegetable oil or the progress of external application hormone ointment
Treatment；Serious can add takes antihistaminicum preparation or sedative to alleviate symptom.Vegetable oil is smeared just for red wind
A reason in the stock origin cause of formation works, and can only be that the slight red hip of symptom are effective.Frequently or a large amount of or prolonged application contains skin
The drug of matter hormone has the side effect of whole body and local skin, and the local skin side effect containing corticosteroid drug is more prominent
Be drug-dependent dermatitis and rebound dermatitis, steroid dependent dermatitis, atrophoderma, relaxation, because of blood capillary may be caused
Enlargement of pipe causes cheek to redden, pigmentation, skin susceptible, and crinosity or even generation system influence, and inhibit growth and development,
And the side effects such as immunity degradation.
Prior art treatment diaper rash mostly uses greatly following two methods：
A, vegetable oil is smeared.This method can only be effective to slight diaper rash.
B, it is smeared and is treated using external application hormone ointment.External application hormone ointment is treated；Serious can add takes anti-group
Amine preparation or sedative are knitted to alleviate symptom.It smears vegetable oil to work just for a reason in the red hip origin cause of formation, only
Can be that the slight red hip of symptom are effective.Frequent or a large amount of or drug of the prolonged application containing cortin, has whole body and skin
The side effect of skin part, the local skin side effect containing corticosteroid drug it is more prominent be drug-dependent dermatitis and it is rebound
Dermatitis may cause steroid dependent dermatitis, and atrophoderma, relaxation, because telangiectasis causes cheek to redden, pigment is heavy
It, skin susceptible, crinosity or even generation system influence, and inhibit the side effects such as growth and development and immunity degradation.
Using the method for smearing vegetable oil or painting hormone ointment of the prior art it is of course possible to use, otherwise but it can only be right
Slight diaper rash is effective or side effect is big.The using effect of the drug of the treatment diaper rash of the prior art is ideal not enough.
Invention content
In order to overcome the deficiencies of the prior art, the present invention provides a kind of external application without hormone constituted using pure natural components
Treat the preparation method of the plant extract Chinese medicine composition of diaper rash, the product good effect prepared, Small side effects, user
Just, using effect is more preferable.
The present invention is technical solution used by reaching above-mentioned technical purpose：A kind of plant of external curing diaper rash carries
The preparation method of Chinese medicine composition, raw material is taken to include by weight：1.5-2.5 parts of water, 45-55 parts of vaseline, camellia seed oil 25-
30 parts, 1-2 parts of synthetic wax, 1.5-2.5 parts of Chinese gall, 1.5-2.5 parts of polyglyceryl-3 diisostearate, moutan bark 1.5-2.5
Part, 1-2 parts of Asian puccoon, 1-2 parts of alum, 1-2 parts of cuttle bone, 1-2 parts of Radix stemonae japonicae, 1-2 parts of cloves bud, 1-2 parts of purslane, product
Avenge 1-2 parts of grass, 1-2 parts of sorrel root, 0.08-0.12 parts of menthol, 0.15-0.25 parts of methyl hydroxybenzoate, hexylene glycol 0.05-
0.08 part, 0.05-0.08 parts of Chlorphenesin, 0.05-0.08 parts of Phenoxyethanol；Preparation method includes the following steps：
Step A, oil phase thing mixing extraction：The Asian puccoon of corresponding parts by weight, cloves bud, moutan bark, camellia seed oil are placed in
After mixing is impregnated 24-30 hours in container, the liquid object in mixture is separated by filtration spare；
Step B, aqueous-phase material mixing extraction：By the water of corresponding parts by weight, Chinese gall, alum, cuttle bone, centella, palm leaf
Big xanthorrhiza, purslane, Radix stemonae japonicae are placed in container, 40-50 DEG C of water temperature, after impregnating 36-48 hours, by the liquid in mixture
Object is separated by filtration spare；
Step C, oil phase mixes：The vaseline of corresponding parts by weight is added in the liquid object filtered to isolate in above-mentioned steps A, is closed
At wax, polyglyceryl-3 diisostearate, it is heated to 75-85 DEG C after mixing, heating time 30-45 minute, is uniformly mixing to obtain
Oil mixture it is spare；
Step D, water phase mixes：The liquid object filtered to isolate in above-mentioned steps B is added to the menthol of corresponding parts by weight
75-85 DEG C is heated to after mixing, heating time 30-45 minute, the aqueous mixture being uniformly mixing to obtain is spare；
Step E, mixing and emulsifying：The oil mixture obtained in above-mentioned steps C is mixed with the water phase obtained in above-mentioned steps D
Close object mixing and emulsifying obtain mixing and emulsifying object, by mixing and emulsifying object be cooled to 45-55 DEG C it is spare；
Step F, preservative is added：Corresponding weight will be added in the mixing and emulsifying object after cooling obtained in above-mentioned E steps
The methyl hydroxybenzoate, hexylene glycol, Chlorphenesin, Phenoxyethanol of part are mixed evenly rear natural cooling and obtain product.
The beneficial effects of the invention are as follows：Due to being the external curing diaper rash without hormone constituted using pure natural components
Plant extract Chinese medicine composition preparation method, the product good effect prepared, Small side effects, easy to use, using effect
More preferably.
Specific implementation mode
With reference to embodiment, the invention will be further described：
Embodiment 1, a kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash, raw material is by weight
Part include：1.5 parts of water, 45 parts of vaseline, 25 parts of camellia seed oil, 1 part of synthetic wax, 1.5 parts of Chinese gall, two isostearic acid of polyglycereol -3
1.5 parts of ester, 1.5 parts of moutan bark, 1 part of Asian puccoon, 1 part of alum, 1 part of cuttle bone, 1 part of Radix stemonae japonicae, 1 part of cloves bud, purslane 1
Part, 1 part of centella, 1 part of sorrel root, 0.08 part of menthol, 0.15 part of methyl hydroxybenzoate, 0.05 part of hexylene glycol, Chlorphenesin
0.05 part, 0.05 part of Phenoxyethanol；Preparation method includes the following steps：
Step A, oil phase thing mixing extraction：The Asian puccoon of corresponding parts by weight, cloves bud, moutan bark, camellia seed oil are placed in
After mixing is impregnated 24 hours in container, the liquid object in mixture is separated by filtration spare；
Step B, aqueous-phase material mixing extraction：By the water of corresponding parts by weight, Chinese gall, alum, cuttle bone, centella, palm leaf
Big xanthorrhiza, purslane, Radix stemonae japonicae are placed in container, 40 DEG C of water temperature, and after impregnating 36 hours, the liquid object in mixture is passed through
Filter separation is spare；
Step C, oil phase mixes：The vaseline of corresponding parts by weight is added in the liquid object filtered to isolate in above-mentioned steps A, is closed
At wax, polyglyceryl-3 diisostearate, it is heated to 75 DEG C after mixing, 30 minutes heating times, the oil phase being uniformly mixing to obtain
Mixture is spare；
Step D, water phase mixes：The liquid object filtered to isolate in above-mentioned steps B is added to the menthol of corresponding parts by weight
75 DEG C are heated to after mixing, 30 minutes heating times, the aqueous mixture being uniformly mixing to obtain is spare；
Step E, mixing and emulsifying：The oil mixture obtained in above-mentioned steps C is mixed with the water phase obtained in above-mentioned steps D
Close object mixing and emulsifying obtain mixing and emulsifying object, by mixing and emulsifying object be cooled to 45 DEG C it is spare；
Step F, preservative is added：Corresponding weight will be added in the mixing and emulsifying object after cooling obtained in above-mentioned E steps
The methyl hydroxybenzoate, hexylene glycol, Chlorphenesin, Phenoxyethanol of part are mixed evenly rear natural cooling and obtain product.
Embodiment 2, a kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash, raw material is by weight
Part include：2.5 parts of water, 55 parts of vaseline, 30 parts of camellia seed oil, 2 parts of synthetic wax, 2.5 parts of Chinese gall, two isostearic acid of polyglycereol -3
2.5 parts of ester, 2.5 parts of moutan bark, 2 parts of Asian puccoon, 2 parts of alum, 2 parts of cuttle bone, 2 parts of Radix stemonae japonicae, 2 parts of cloves bud, purslane 2
Part, 2 parts of centella, 2 parts of sorrel root, 0.12 part of menthol, 0.25 part of methyl hydroxybenzoate, 0.08 part of hexylene glycol, Chlorphenesin
0.08 part, 0.08 part of Phenoxyethanol；Preparation method includes the following steps：
Step A, oil phase thing mixing extraction：The Asian puccoon of corresponding parts by weight, cloves bud, moutan bark, camellia seed oil are placed in
After mixing is impregnated 30 hours in container, the liquid object in mixture is separated by filtration spare；
Step B, aqueous-phase material mixing extraction：By the water of corresponding parts by weight, Chinese gall, alum, cuttle bone, centella, palm leaf
Big xanthorrhiza, purslane, Radix stemonae japonicae are placed in container, 50 DEG C of water temperature, and after impregnating 48 hours, the liquid object in mixture is passed through
Filter separation is spare；
Step C, oil phase mixes：The vaseline of corresponding parts by weight is added in the liquid object filtered to isolate in above-mentioned steps A, is closed
At wax, polyglyceryl-3 diisostearate, it is heated to 85 DEG C after mixing, 45 minutes heating times, the oil phase being uniformly mixing to obtain
Mixture is spare；
Step D, water phase mixes：The liquid object filtered to isolate in above-mentioned steps B is added to the menthol of corresponding parts by weight
85 DEG C are heated to after mixing, 45 minutes heating times, the aqueous mixture being uniformly mixing to obtain is spare；
Step E, mixing and emulsifying：The oil mixture obtained in above-mentioned steps C is mixed with the water phase obtained in above-mentioned steps D
Close object mixing and emulsifying obtain mixing and emulsifying object, by mixing and emulsifying object be cooled to 55 DEG C it is spare；
Step F, preservative is added：Corresponding weight will be added in the mixing and emulsifying object after cooling obtained in above-mentioned E steps
The methyl hydroxybenzoate, hexylene glycol, Chlorphenesin, Phenoxyethanol of part are mixed evenly rear natural cooling and obtain product.
Embodiment 3, a kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash, raw material is by weight
Part include：2 parts of water, 50 parts of vaseline, 28 parts of camellia seed oil, 1.5 parts of synthetic wax, 2 parts of Chinese gall, polyglyceryl-3 diisostearate
2 parts, 2 parts of moutan bark, 1.5 parts of Asian puccoon, 1.5 parts of alum, 1.5 parts of cuttle bone, 1.5 parts of Radix stemonae japonicae, 1.5 parts of cloves bud, horse
1.5 parts of bitterroot, 1.5 parts of centella, 1.5 parts of sorrel root, 0.1 part of menthol, 0.2 part of methyl hydroxybenzoate, 0.07 part of hexylene glycol,
0.06 part of Chlorphenesin, 0.07 part of Phenoxyethanol；Preparation method includes the following steps：
Step A, oil phase thing mixing extraction：The Asian puccoon of corresponding parts by weight, cloves bud, moutan bark, camellia seed oil are placed in
After mixing is impregnated 27 hours in container, the liquid object in mixture is separated by filtration spare；
Step B, aqueous-phase material mixing extraction：By the water of corresponding parts by weight, Chinese gall, alum, cuttle bone, centella, palm leaf
Big xanthorrhiza, purslane, Radix stemonae japonicae are placed in container, 45 DEG C of water temperature, and after impregnating 42 hours, the liquid object in mixture is passed through
Filter separation is spare；
Step C, oil phase mixes：The vaseline of corresponding parts by weight is added in the liquid object filtered to isolate in above-mentioned steps A, is closed
At wax, polyglyceryl-3 diisostearate, it is heated to 80 DEG C after mixing, 38 minutes heating times, the oil phase being uniformly mixing to obtain
Mixture is spare；
Step D, water phase mixes：The liquid object filtered to isolate in above-mentioned steps B is added to the menthol of corresponding parts by weight
80 DEG C are heated to after mixing, 37 minutes heating times, the aqueous mixture being uniformly mixing to obtain is spare；
Step E, mixing and emulsifying：The oil mixture obtained in above-mentioned steps C is mixed with the water phase obtained in above-mentioned steps D
Close object mixing and emulsifying obtain mixing and emulsifying object, by mixing and emulsifying object be cooled to 50 DEG C it is spare；
Step F, preservative is added：Corresponding weight will be added in the mixing and emulsifying object after cooling obtained in above-mentioned E steps
The methyl hydroxybenzoate, hexylene glycol, Chlorphenesin, Phenoxyethanol of part are mixed evenly rear natural cooling and obtain product.
The present invention is illustrated further：
The camellia oil prepared in formula is extracted using innovative technology, it is maximum remain in camellia oil to skin it is effective at
Point；The traditional Chinese medicine ingredients in formula are prepared, according to required drug effect in this formula, different modes extraction is respectively adopted, is retained with maximum
Active ingredient in Chinese medicine.Asian puccoon, cloves, moutan bark use camellia oil extraction, have abandoned traditional water or solvent extraction,
Both the purple to the effective ingredient-Acetylshikonin of the red hip of children, beta-hydroxy isovaleryl of the molten part of oil therein can have been extracted
Careless element, alkannin, β, β '-dimethylacrylshikonins, eugenol, aceteugenol, paeonol, paeonoside, paeonol
Former glycosides etc. in turn avoids bringing the other impurities in other dissolvent residuals and formula into；Chinese gall, cuttle bone, overgrows hundred at alum
Portion, purslane, centella, sorrel etc. use low-pressure low-temperature aqueous extraction method, avoid high temperature active ingredient therein.
The present invention is formulated using Water-In-Oil (W/O), and camellia oil and Asian puccoon, cloves, Cortex Moutan extract have skin moist
Heat preservation and film-formation result, moist protective film is formed in skin surface, is conducive to that red hip skin and environmental stimuli ingredient is isolated
Contact acts on eczema skin conducive to effective component of chinese medicine；Water phase in formula is all using Chinese gall, alum, cuttle bone, climing
The water extraction component of the raw tuber of stemona, purslane, centella, sorrel etc., ensure that the Chinese medicine content being entirely formulated.
For the cause of the red hip of children, the red hip of children is made to get well in terms of three：1, by camellia oil and in
The effect of medicament extract, invasion, anti-inflammation and sterilization, the convergence that red hip skin and environmental stimuli environment is isolated are red and swollen, improve skin
Shouting pain；2, Water-In-Oil (W/O) is formulated, and forms continuous waterproof membrane, is isolated in urine stimulant wet, in excrement, sweat, paper diaper
The stimulation of remaining detergent etc. in chemical substance, clothing reduces red hip and forms inducement；3, Chinese gall, centella, alum etc.
Extract can restrain red and swollen skin, the dry and comfortable health of Quick-return skin.Several respects act on simultaneously, to reach the red wind of removal
Stock, smooth skin, the effect for keeping baby's hip health smooth.
Asian puccoon, cloves, moutan bark directly use food grade camellia oil to extract, avoid bringing into other solvents or this formula with
Other outer substances, the oil-phase component in being formulated as this project.Traditional use water extract method or solvent extraction method.It is purple
Grass, cloves, moutan bark are lipophilic components to the active ingredient of red hip skin, and water extraction cannot be extracted effectively in this formula
Active principle.Solvent method can bring other solvents, have negative effect to red hip skin.Directly use food grade camellia oil immersion
It carries, avoids bringing other substances other than other solvents or this formula into.While ensure that effective, and formula is enabled to have followed baby
The pure simple principle of child's cosmetics.
Chinese gall, alum, cuttle bone, Radix stemonae japonicae, purslane, centella, sorrel etc. are extracted using low-pressure low-temperature water
It follows the example of, avoids high temperature active ingredient therein.
Oil-soluble, water-soluble effective component of chinese medicine are fused together to form a Water-In-Oil (W/O) by emulsifying technology
Cream, Water-In-Oil (W/O) cream tend to smear out, are easy to clean, can form continuous waterproof membrane.
Oil-soluble, the water-soluble effective component of chinese medicine being entirely formulated are fused together to form an oil by emulsifying technology
Packet water cream efficiently acts on the red hip of children, and red and swollen, the red and swollen wound of convergence is taken off in quick anti-inflammatory, and skin restores smooth delicacy.
It is formulated using Water-In-Oil (W/O), (can be difficult to rinse, children can be enabled tender to avoid that glutinous soapy feeling of pure oil formula
Tender skin feels more uncomfortable), also avoid stimulation of oil-in-water (O/W) formula to red hip skin.Water-In-Oil (W/O) formula is advantageous
In forming continuous waterproof membrane, can be effectively isolated urine stimulant wet, in excrement, sweat, the chemical substance in paper diaper, in clothing
The stimulation of remaining detergent etc. reduces red hip and forms inducement.
Major technique and performance indicator：
Appearance, smell：Dark brown exquisiteness lotion, specific taste of traditional Chinese medicine
Fusing point：48-53℃
Viscosity：12000-16000mPa.s
Pass through research and development in 06 months 1 year, 100 many cases under being supervised by pediatrician with product prepared by this technology
The test of the red hip skin of children improves by more than ten formula adjustment, obtains child skin section doctor and 200 multidigits are red
The affirmative of the mother of hip children.Product prepared by this technology is melted the oil of Chinese medicine, water active ingredient by emulsifying hybrid technology
It is combined together, than single lipophilic component or 80% or more single water-soluble composition improvement effect, fully acts on red hip skin, from
And take effect, general light, moderate red hip red and swollen can subside after smearing for 2 hours, and skin wound can close up two days later,
Mild non-stimulated, safe maintenance children skin enables children's wind wind skin restore smooth delicacy, and makees that the poison of hormone ointment is not secondary
With.
Claims (1)
1. a kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash, which is characterized in that its raw material is by weight
Measuring part includes：1.5-2.5 parts of water, 45-55 parts of vaseline, 25-30 parts of camellia seed oil, 1-2 parts of synthetic wax, 1.5-2.5 parts of Chinese gall,
1.5-2.5 parts of polyglyceryl-3 diisostearate, 1.5-2.5 parts of moutan bark, 1-2 parts of Asian puccoon, 1-2 parts of alum, cuttle bone 1-2
Part, 1-2 parts of Radix stemonae japonicae, 1-2 parts of cloves bud, 1-2 parts of purslane, 1-2 parts of centella, 1-2 parts of sorrel root, menthol
0.08-0.12 parts, 0.15-0.25 parts of methyl hydroxybenzoate, 0.05-0.08 parts of hexylene glycol, 0.05-0.08 parts of Chlorphenesin, benzene oxygen second
0.05-0.08 parts of alcohol；Preparation method includes the following steps：
Step A, oil phase thing mixing extraction：The Asian puccoon of corresponding parts by weight, cloves bud, moutan bark, camellia seed oil are placed in container
After middle mixing is impregnated 24-30 hours, the liquid object in mixture is separated by filtration spare；
Step B, aqueous-phase material mixing extraction：By the water of corresponding parts by weight, Chinese gall, alum, cuttle bone, centella, sorrel
Root, purslane, Radix stemonae japonicae are placed in container, 40-50 DEG C of water temperature, and after impregnating 36-48 hours, the liquid object in mixture is passed through
It is separated by filtration spare；
Step C, oil phase mixes：The liquid object filtered to isolate in above-mentioned steps A is added to vaseline, the synthesis of corresponding parts by weight
Wax, polyglyceryl-3 diisostearate are heated to 75-85 DEG C, heating time 30-45 minute, are uniformly mixing to obtain after mixing
Oil mixture is spare；
Step D, water phase mixes：The menthol that the liquid object filtered to isolate in above-mentioned steps B is added to corresponding parts by weight mixes
After be heated to 75-85 DEG C, heating time 30-45 minute, the aqueous mixture being uniformly mixing to obtain is spare；
Step E, mixing and emulsifying：The aqueous mixture that will be obtained in the oil mixture obtained in above-mentioned steps C and above-mentioned steps D
Mixing and emulsifying obtains mixing and emulsifying object, by mixing and emulsifying object be cooled to 45-55 DEG C it is spare；
Step F, preservative is added：Corresponding parts by weight will be added in the mixing and emulsifying object after cooling obtained in above-mentioned E steps
Methyl hydroxybenzoate, hexylene glycol, Chlorphenesin, Phenoxyethanol are mixed evenly rear natural cooling and obtain product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810769188.4A CN108671176A (en) | 2018-07-13 | 2018-07-13 | A kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810769188.4A CN108671176A (en) | 2018-07-13 | 2018-07-13 | A kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108671176A true CN108671176A (en) | 2018-10-19 |
Family
ID=63813881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810769188.4A Pending CN108671176A (en) | 2018-07-13 | 2018-07-13 | A kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108671176A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109700700A (en) * | 2019-03-14 | 2019-05-03 | 福建百想生物科技有限公司 | A kind of baby camellia diaper ointment and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1985899A (en) * | 2006-12-26 | 2007-06-27 | 刘永敦 | Externally applied medicine for treating burns and scalds and its preparing method |
| CN104288254A (en) * | 2014-10-13 | 2015-01-21 | 杭州莫诺生物科技有限公司 | Traditional Chinese medicine powder special for treating diaper dermatitis in infants |
| CN107811950A (en) * | 2017-12-06 | 2018-03-20 | 佛山微赢电子商务有限公司 | A kind of stern protection cream to baby's skin with nursing effect and preparation method thereof |
-
2018
- 2018-07-13 CN CN201810769188.4A patent/CN108671176A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1985899A (en) * | 2006-12-26 | 2007-06-27 | 刘永敦 | Externally applied medicine for treating burns and scalds and its preparing method |
| CN104288254A (en) * | 2014-10-13 | 2015-01-21 | 杭州莫诺生物科技有限公司 | Traditional Chinese medicine powder special for treating diaper dermatitis in infants |
| CN107811950A (en) * | 2017-12-06 | 2018-03-20 | 佛山微赢电子商务有限公司 | A kind of stern protection cream to baby's skin with nursing effect and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109700700A (en) * | 2019-03-14 | 2019-05-03 | 福建百想生物科技有限公司 | A kind of baby camellia diaper ointment and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102614102B (en) | Dandruff-removing medicinal composition and preparation method thereof | |
| AU2021102002A4 (en) | Combined plant extract for getting rid of mites and acne and preparation method and use thereof | |
| CN104940084B (en) | Massage oil after pure natural bath | |
| CN105853260A (en) | Cream for treating diaper dermatitis and preparation method thereof | |
| CN102302439A (en) | Health-care bath foam and preparation method thereof | |
| CN109260054A (en) | A kind of plant mosquito-repellent antipruritic cream and preparation method thereof | |
| CN105997785B (en) | A kind of stern protection cream for baby and preparation method thereof | |
| CN105816365A (en) | Pure natural essence oil mosquito-repellent liquid and preparation method thereof | |
| CN104116681A (en) | Hairdressing bath agent and preparation method thereof | |
| CN105194474B (en) | It is a kind of multi-functional except acarid emulsion and preparation method thereof | |
| CN108671176A (en) | A kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash | |
| KR102152752B1 (en) | Aromatic composition containing extract of korean fir for psychological relaxation | |
| DK148469B (en) | COSMETIC PREPARATION AND PROCEDURE FOR ITS PREPARATION | |
| CN102872240B (en) | Compound essential oil for relaxing and activating collaterals | |
| CN106109369A (en) | A kind of anti-wrinkle composition containing Hibiscus manihot L. and anti-wrinkle cream thereof | |
| JPH03106819A (en) | Hypoglycemic drug | |
| CN111040896A (en) | Antibacterial, anti-inflammatory and skin-beautifying handmade soap | |
| CN104666139A (en) | Composite mosquito-repellent toner and preparation method thereof | |
| CN106139077A (en) | A kind of fragrant plant hair growth promoter and preparation method thereof | |
| JP5302526B2 (en) | Artemisia essential oil topical preparation | |
| CN111773167B (en) | Shampoo special for women in puerperal month period and preparation method thereof | |
| CN109172489A (en) | A kind of infant's hygenic towelette and preparation method thereof that mosquito control is bitten | |
| CN107854360A (en) | A kind of shampoo used also as bath lotion and preparation method thereof | |
| CN108567944A (en) | A kind of preparation method of the plant extract Chinese medicine composition of external curing eczema | |
| KR20180088349A (en) | Earthworm fermented extracts and method for manuracturing thereof and natural cosmetics and functional health food comprising same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181019 |
|
| RJ01 | Rejection of invention patent application after publication |