CN104288254A - Traditional Chinese medicine powder special for treating diaper dermatitis in infants - Google Patents
Traditional Chinese medicine powder special for treating diaper dermatitis in infants Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
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- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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Abstract
The invention discloses traditional Chinese medicine powder special for treating diaper dermatitis in infants. The medicine comprises the following components in parts by weight: 10 parts of rheum officinale, 10 parts of coptis chinensis, 12 parts of Chinese gall and 12 parts of dried alum. The traditional Chinese medicine powder is simple in compatibility of medicines, convenient to manufacture and low in cost, can relieve symptoms such as redness and swelling and ulceration generated by diaper dermatitis in infants and does not have any toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, especially a kind of Chinese powder medicine for the treatment of bady's diaper dermatitis.
Background technology
It is red that diaper dermatitis is commonly called as buttocks, is the very multiple dermal inflammatory pathological changes of infant, and its clinical main manifestations is that the symptoms such as rubescent, vesicle, erosion, pimple, ulcer appear in partial skin.According to the order of severity of diaper dermatitis, generally can be divided into three kinds: slightly show as erubescence and erythra shows as chestnut grain sample, concentrate on perineal position and and buttocks perianal 2cm-3cm place may be involved; Moderate shows as erythra affects whole baby buttocks, or large stretch of erythra is connected, and continues development and then occurs transudate, form the ulcer of shallow table, and can with erythema, pimple; Severe shows as erythra to extension and the diffusion of the place such as femoribus internus or stomach wall, and pudendum exfoliation, easily develops into decubital ulcer, even causes septicemia time serious.
For the cause of disease that diaper dermatitis produces, doctor trained in Western medicine be it is generally acknowledged: the impact being subject to wet diaper hectic fever microenvironment, breed rapidly with the antibacterial of skin surface and decompose the carbamide contained by urine in infant feces, produce a large amount of ammonia, skin this wet diaper of Long contact time under stuffy, air-locked state that infant is tender and lovely, causes stimulating aggravation and occurring red and swollen; If diaper is not cleaned, diaper both may speckle with the alkaline matter such as detergent and soap stain, can remain again the acidic materials such as urine and feces of infant, above two class materials all can bring out and increase the weight of diaper dermatitis; The material of the poor air permeability such as some father and mother's life-time service oilcloth, blanket and plastics makes diaper, because steam is difficult to effusion, adds the repeatedly friction of diaper to skin, causes the generation of diaper dermatitis.
Stress the concern to " exopathogenic factor " relative to doctor trained in Western medicine, the more angles from " internal and external reasons is dialectical " of the traditional Chinese medical science consider the origin cause of formation of diaper dermatitis.The traditional Chinese medical science is thought: the life of endogenous dampness, and how by dysfunction of the spleen, the wet of water paddy is not changed; Exogenous damp is the damp of six climate exopathogens, the wetting or lying on bed for a long time wetland in mist dew of wound.Because infant spleen and stomach function is more weak, be difficult to discharge dampness, therefore dampness easily smoulders in vivo.Add infant resistance on the low side, the dampness of diaper and even air invades human body, causes " damp syndrome " by cutaneous manifestations out.
Diaper ointment in the market, main component comprises vaseline, zinc oxide, sodium lactate etc., some product even also added essence, its shortcoming is: 1. diaper ointment belongs to ointment product, when being applied in skin use, poor air permeability easily makes skin produce anaerobic respiration, and then cutaneous comfort level; 2. irritation effect is produced to skin, smear this product and have glutinous soapy feeling when skin, if the overlong time that this product is Dermallly affixed, easily cause skin to itch, scratch, because the skin of infant is usually tenderer, excessive scratching meeting lesional epidermis layer, and then affect skin infection antibacterial; 3. commercially available diaper ointment raw material is mainly chemical medicine product, virtually makes the side effect of skin irritation strengthen further; To sum up, cause commercially available prod very not remarkable for the therapeutic effect of infant dermatitis.
Application number be 03109736.7 patent document disclose a kind of Chinese medicine compound ointment, be mainly made up of Rhizoma Coptidis, Galla Chinensis and other adjuvant.Preparation method is that Rhizoma Coptidis is for subsequent use through pulverizing; Carry out spraying dry after concentrated after Galla Chinensis warm macerating, obtain powder; Both add in simple Ointment substrate, obtained ointment.The weak point of this technical scheme is: this product is ointment poor air permeability, and after applying ointment or plaster for a long time, the easy anaerobic respiration of skin, can, to irritating side effect such as skin bring skin to itch, cause final therapeutic effect not good after the time is long.
Application number be 201310178076.9 patent document disclose a kind of Chinese medicinal ointment for the treatment of infant diaper rash and preparation method thereof, primary raw material medicine has Flos Lonicerae, Indigo Naturalis, Talcum, Folium Mori, Herba Violae, Radix Cynanchi Atrati, Fructus Arctii, Rhizoma Coptidis, Borneolum Syntheticum, Radix Arnebiae (Radix Lithospermi), Cortex Phellodendri, Radix Scutellariae, the Rhizoma Atractylodis Macrocephalae.The weak point of this technical scheme is: 1. this product is unguentum poor air permeability, and after applying ointment or plaster for a long time, the easy anaerobic respiration of skin, can to irritating side effect such as skin bring skin to itch after the time is long; 2. this unguentum medication become be grouped into complexity, raw material and manufacturing cost high; 3. in composition, contain Talcum, and Talcum is carcinogen, creates very large impact to the safe handling of infant, causes final therapeutic effect not good.
Summary of the invention
For existing deficiency, the invention provides a kind of Chinese powder medicine being exclusively used in treatment bady's diaper dermatitis, this Chinese powder medicine has good therapeutic effect to bady's diaper dermatitis, and to no skin irritation effect.
Treat a Chinese powder medicine for bady's diaper dermatitis, be made up of the raw material of following weight proportion: Radix Et Rhizoma Rhei 5-15 part, Rhizoma Coptidis 5-15 part, Galla Chinensis 7-17 part and dried Alumen 7-17 part.
Preferably, be made up of the raw material of following weight proportion: Radix Et Rhizoma Rhei 10 parts, Rhizoma Coptidis 10 parts, Galla Chinensis 12 parts and dried Alumen 12 parts.
Be exclusively used in a preparation method for the Chinese powder medicine for the treatment of bady's diaper dermatitis, comprise the steps: to take the Radix Et Rhizoma Rhei of recipe quantity, Rhizoma Coptidis, Galla Chinensis and dried Alumen, cut into slices respectively, cure, damp eliminating is dry; Dried Radix Et Rhizoma Rhei, Rhizoma Coptidis, Galla Chinensis and dried Alumen are ground to form fine powder respectively, crosses 200 mesh sieves, mixed-powder, and polish, autoclaving, obtained.
Preferably, fine powder is the powder of particle diameter 50 ~ 70 μm.
Preferably, pressure during autoclaving is 104.0 ~ 137.3kPa, and sterilising temp is 121 ~ 126 DEG C.
Preferred, take the Radix Et Rhizoma Rhei of recipe quantity, Rhizoma Coptidis, Galla Chinensis and dried Alumen, cut into slices respectively, cure, at 124 DEG C, carry out damp eliminating drying; Dried Radix Et Rhizoma Rhei, Rhizoma Coptidis, Galla Chinensis and dried Alumen are ground to form respectively the fine powder of particle diameter 60 microns, cross 200 mesh sieves, mixed-powder, and polish, sterilizing under the pressure of 120.0kPa, obtained.
Present invention also offers two kinds of usings method of this medicine:
(1) first cleaned up by affected part warm water when using, after drying, get this appropriate Chinese powder medicine in the external application of infant affected part, every day treats 3 times altogether, and treatment 5 days is a course for the treatment of continuously.
(2) first affected part warm water is cleaned up when using, also can select after drying directly appropriate powder powder to be sprinkling upon on diaper, be reached the object of smearing by diaper.
In the present invention, effect of each raw material is respectively:
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature, attack stagnant, clearing away damp-heat, purging fire and cooling blood, blood stasis dispelling detoxifies;
Rhizoma Coptidis: bitter in the mouth, cold in nature, heat clearing away, dampness, eliminating fire and detoxication;
Galla Chinensis: sour in the mouth, puckery, cold in nature, hidroschesis of astringing the lung, astringing intestine to stop diarrhea controlling nocturnal emission with astringent drugs, hemostasis removing toxic substances;
Dried Alumen: sour in the mouth, cold in nature, expectorant dampness, antidiarrheal is stopped blooding, removing toxic substances parasite killing.
The Chinese powder medicine prescription being exclusively used in treatment bady's diaper dermatitis provided by the invention, compared with prior art, has the following advantages:
(1) potentiation is combined:
Heat-clearing and toxic substances removing: in product composition, Radix Et Rhizoma Rhei and Rhizoma Coptidis have the effects such as heat clearing away, pathogenic fire purging, removing toxic substances, can comparatively fast make symptom be eased;
Opposing is infected: patient has inflammation performance, hygrothermal environment and grow each bacterioid, and the emodin in product composition, coptisine have the effect to anti-Staphylococcus aureus, Hemolytic streptococcus, Bacillus proteus;
Removing dampness sore: in product composition, dried Alumen has effect of removing dampness sore hemostasis, and the ammonia that can absorb rapidly excessive moisture and be decomposed by urine, helps impaired wound surface skin contraction simultaneously, accelerates dry caking, has good result of use for serious symptom infant patients;
Form protecting film: in product composition, Galla Chinensis contains tannin and tannic acid, after skin ulcer face, mucosa are in contact with it, namely tissue protein is solidified, the protecting film that one deck is natural can be formed, good astriction can be played, promote that thin vessels is forced to shrink simultaneously, bleed and therefore condense and possess the function of hemostasis;
Moistureproof water-resisting property: because Galla Chinensis in product composition contains tannin and tannic acid; the protecting film that one deck is natural can be formed; so this product has moistureproof water-resisting property; the material such as product and water is avoided to mix; original form of this product can be kept preferably; be conducive to ensureing product quality, have good result of use to infant patients.
(2) nonirritant:
Take vegetable material as the raw material of this product, pure natural, nonirritant compared with chemical drugs, this Chinese powder medicine is have higher breathability after Powdered use, can not cutaneous comfort level, product when skin without glutinous soapy feeling, can effectively avoid because long skin service time is airtight, cause chafe and produce the generation of the situations such as skin is itched, scratching, redness, ulcer symptoms that bady's diaper dermatitis produces can be alleviated, using natural Chinese medicines formula, nontoxic, have no side effect.
(3) using method is simple:
First cleaned up by affected part warm water during use, after drying, desirable this Chinese powder medicine is in right amount in the external application of infant affected part, also can select directly appropriate powder powder to be sprinkling upon on diaper, reached the object of smearing by diaper, the using method of this product is simple, convenient operation.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with specific embodiment and experiment, but its protection domain is not limited.
A kind of Chinese powder medicine for the treatment of bady's diaper dermatitis of the present invention, the technical scheme taked is: medicine composition by its weight proportion is: Radix Et Rhizoma Rhei 5-15 part, Rhizoma Coptidis 5-15 part, Galla Chinensis 7-17 part and dried Alumen 7-17 part.
Embodiment 1:
Prescription forms: containing Radix Et Rhizoma Rhei 2.27g, Rhizoma Coptidis 2.27g, Galla Chinensis 2.73g, dried Alumen 2.73g in every 10g medicine.
A kind of preparation method being exclusively used in the Chinese powder medicine for the treatment of bady's diaper dermatitis:
Take Radix Et Rhizoma Rhei 2.27g, Rhizoma Coptidis 2.27g, Galla Chinensis 2.73g, dried Alumen 2.73g, cut into slices respectively, cure, carry out damp eliminating drying; Dried Radix Et Rhizoma Rhei, Rhizoma Coptidis, Galla Chinensis and dried Alumen are ground to form respectively the fine powder of particle diameter 60 microns, cross 200 mesh sieves, mixed-powder, and polish, under the pressure and 124 DEG C of temperature of 120.0kPa, carry out sterilizing, obtained.
Embodiment 2:
Prescription forms: containing Radix Et Rhizoma Rhei 2.27g, Rhizoma Coptidis 2.27g, Galla Chinensis 2.73g, dried Alumen 2.73g in every 10g medicine.
A kind of preparation method being exclusively used in the Chinese powder medicine for the treatment of bady's diaper dermatitis:
Take Radix Et Rhizoma Rhei 2.27g, Rhizoma Coptidis 2.27g, Galla Chinensis 2.73g, dried Alumen 2.73g, cut into slices respectively, cure, carry out damp eliminating drying; Dried Radix Et Rhizoma Rhei, Rhizoma Coptidis, Galla Chinensis and dried Alumen are ground to form respectively the fine powder of particle diameter 50 microns, cross 200 mesh sieves, mixed-powder, and polish, under the pressure and 124 DEG C of temperature of 120.0kPa, carry out sterilizing, obtained.
Embodiment 3:
Prescription forms: containing Radix Et Rhizoma Rhei 2.27g, Rhizoma Coptidis 2.27g, Galla Chinensis 2.73g, dried Alumen 2.73g in every 10g medicine.
A kind of preparation method being exclusively used in the Chinese powder medicine for the treatment of bady's diaper dermatitis:
Take Radix Et Rhizoma Rhei 2.27g, Rhizoma Coptidis 2.27g, Galla Chinensis 2.73g, dried Alumen 2.73g, cut into slices respectively, cure, carry out damp eliminating drying; Dried Radix Et Rhizoma Rhei, Rhizoma Coptidis, Galla Chinensis and dried Alumen are ground to form respectively the fine powder of particle diameter 70 microns, cross 200 mesh sieves, mixed-powder, and polish, under the pressure and 124 DEG C of temperature of 120.0kPa, carry out sterilizing, obtained.
Test example: the analysis carrying out clinical trial with the medicine that embodiment 1 is obtained
1. subjects
Choose 50 routine diaper dermatitis infants, wherein man 27 example, female 23 example, children age is 8-30 days, and the mean age is (13 ± 2) sky.According to patient admits's time, above infant is divided into treatment group and matched group at random, often organizes each 25 routine infants.Man 14 example in treatment group, female 11 example; Children age 8-25 days, mean age (13 ± 1.5) sky; Wherein skin lesion occurs in perineum part infant 10 example, skin lesion occurs in buttocks infant 5 example, skin lesion occurs in burst inside line infant 6 example, skin lesion occurs in hypogastric region infant 4 example, according to diaper rash symptom in various degree, its mild or moderate infant diaper rash accounts for 12 examples, and moderate infant diaper rash accounts for 8 examples, and severe infant diaper rash accounts for 5 examples.Man 13 example in matched group, female 12 example; Children age is 10-30 days, and the mean age is (12 ± 2) sky; Wherein skin lesion occurs in perineum part infant 9 example, skin lesion occurs in buttocks infant 8 example, skin lesion occurs in burst inside line infant 4 example, skin lesion occurs in hypogastric region infant 4 example, according to diaper rash symptom in various degree, its mild or moderate infant diaper rash accounts for 11 examples, and moderate infant diaper rash accounts for 9 examples, and severe infant diaper rash accounts for 5 examples.Contrast the basic document such as sex, age, cutaneous lesion of two groups of infants, no significant difference, p>0.05, has comparability.
2. Therapeutic Method
Treatment group infant uses the Chinese powder medicine (i.e. this product) of embodiment 1, matched group infant uses commercially available diaper ointment (i.e. reference substance), two groups of infants first clean damage location with warm water before treating, dry after cleaning, external application for curing group or matched group product used are in skin damage place, treat 3 every day, treatment 5 days is a course for the treatment of continuously.
3. efficacy determination
Observe the external application effect of infant skin lesion sites, be divided into healing, this level Four effect effective, effective, invalid; Wherein cure and thoroughly disappear for skin lesion, skin lesion place skin returns to normal condition; Effectively significantly to alleviate for skin lesion symptom has; Effectively for skin lesion symptom has slight alleviating; Invalid is compare zero difference before skin lesion symptom and treatment.
Calculate total effective rate=[(curing number of cases+effective number of cases)/total number of cases] × 100%.Two groups of infant skin lesion resume speeds are compared.
4. statistical method
This experimental data adopts SPSS13.0 software to carry out statistical analysis, and wherein measurement data contrast adopts t inspection, and enumeration data contrast adopts X 2 test, with p < 0.05 for difference has statistical significance.
5. therapeutic outcome and analysis
Table 1 uses this product to contrast with the therapeutic effect of reference substance
Result of the test shows: the routine infant for the treatment of group 25 cures 23 examples, and proportion is 92.0%; Effective 1 example, proportion is 4.0%; Effective 1 example, proportion is 4.0%; Therefore total effective rate is 96.0%; The routine infant of matched group 25 cures 16 examples, and proportion is 64.0%, effective 2 examples, shared by
Ratio is 8.0%, effective 5 examples, and proportion is 20.0%, and invalid 2 examples, proportion 8.0%, total effective rate is 72.0%.Contrast between two groups of infant therapeutic effect has the significance difference opposite sex, has statistical significance (p<0.05).According to statistical result, can show that infant uses Chinese powder medicine of the present invention to treat diaper dermatitis conclusion evident in efficacy.
Treatment group infant skin lesion healing time is 2-4 days, and Mean Time To Recovery is 3 days; Matched group infant skin lesion recovery time is 3-6 days, and Mean Time To Recovery is 5 days.Contrast between two groups of infant skin lesion recovery times has the significance difference opposite sex, has statistical significance (t=11.2045, p<0.05).According to statistical result, can show that infant uses Chinese powder medicine of the present invention can shorten the conclusion of skin lesion healing time.
Table 2 uses the therapeutic effect contrast of this product in different onset position
| ? | Perineal position | Buttocks | Stock inner side | Hypogastric region |
| Patient numbers | 10 | 5 | 6 | 4 |
| Healing time | Average cure time (3.5 days) | Average cure time (2.5 days) | Average cure time (3 days) | Average cure time (3 days) |
| Cure rate | Cure rate (90%) | Cure rate (100%) | Cure rate (100%) | Cure rate (75%) |
| Total effective rate | 90% | 100% | 100% | 100% |
Result of the test shows: skin lesion occurs in perineum part infant 10 example, cure 9 examples, effective 1 example, known cure rate is 90.0%, total effective rate is 90.0%, its average cure time is 3.5 days, skin lesion occurs in buttocks infant 5 example, cure 5 examples, proportion is 100.0%, its average cure time is 2.5 days, skin lesion occurs in burst inside line infant 6 example, cure 6 examples, proportion is 100.0%, its average cure time is 2.5 days, skin lesion occurs in hypogastric region infant 4 example, cure 3 examples, proportion is 75.0%, effective 1 example, proportion is 25.0%, its average cure time is 3 days, according to statistical result, can show that the diaper dermatitis cure rate that infant uses Chinese powder medicine of the present invention to treat inside skin buttocks and stock is best, the diaper dermatitis cure rate of perineal position takes second place, underbelly diaper dermatitis cure rate is relatively low, because disease site is fewer in number at hypogastric region, but from total effective rate analysis, underbelly therapeutic effect still obviously, can show that the diaper dermatitis of Chinese powder medicine of the present invention treatment skin diverse location treats all effectively significant conclusion.
Use this product and reference substance for the therapeutic effect contrast of infant diaper rash in various degree
| ? | Slight infant diaper rash | Moderate infant diaper rash | Severe infant diaper rash |
| This product patient numbers/reference substance patient numbers | 12/11 | 8/9 | 5/5 |
| The cure rate of the cure rate/reference substance of this product | Cure rate (100%)/cure rate (81.2%) | Cure rate (87.5%)/cure rate (55.6%) | Cure rate (80%)/cure rate (20%) |
| The aggregate efficiency of the aggregate efficiency/reference substance of this product | 100%/91% | 100%/66.7% | 80%/20% |
| The average cure time of the average cure time/reference substance of this product | (2 days)/(3 days) | (3 days)/(5 days) | (5 days)/(7 days) |
This product: its mild or moderate infant diaper rash accounts for 12 examples, cure 12 examples, proportion is 100.0%, have its average cure time to be 2 days, moderate infant diaper rash accounts for 8 examples, cures 7 examples, proportion is 87.5%, effective 1 example, and proportion is 12.5%, its average cure time is 3 days, and severe infant diaper rash accounts for 5 examples, cures 4 examples, proportion is 80.0%, effective 1 example, proportion is 20.0%, and its average cure time is 5 days.
Reference substance: its mild or moderate infant diaper rash accounts for 11 examples, cure 9 examples, proportion is 81.2%, effective 1 example, proportion is 9.1%, has its average cure time to be 3 days, moderate infant diaper rash accounts for 9 examples, and cure 5 examples, proportion is 55.6%, its average cure time is 5 days, and severe infant diaper rash accounts for 5 examples, cures 1 example, proportion is 20.0%, effective 1 example, proportion is 20.0%, and its average cure time is 7 days.
According to statistical result, when slight infant diaper rash situation, this product and reference substance all have good effective percentage and cure rate, this product average cure time and cure rate are dominant slightly, when moderate infant diaper rash situation, this product and reference substance average cure time and cure rate gap larger, this product average cure time is shorter, cure rate is higher, when severe infant diaper rash situation, this product and reference substance have a long way to go at average cure time and cure rate, this product average cure time relative comparison product are shorter, cure rate is higher, and the cure rate of reference substance is very low, average cure time is also very long, can show that this product Chinese powder medicine is relative to reference substance diaper ointment, therapeutic effect and the larger conclusion of healing time gap when treating the diaper dermatitis of skin moderate and severe.
Claims (6)
1. be exclusively used in a Chinese powder medicine for treatment bady's diaper dermatitis, be made up of the raw material of following weight proportion: Radix Et Rhizoma Rhei 5-15 part, Rhizoma Coptidis 5-15 part, Galla Chinensis 7-17 part and dried Alumen 7-17 part.
2. the Chinese powder medicine being exclusively used in treatment bady's diaper dermatitis according to claim 1, is characterized in that, be made up of the raw material of following weight proportion: Radix Et Rhizoma Rhei 10 parts, Rhizoma Coptidis 10 parts, Galla Chinensis 12 parts and dried Alumen 12 parts.
3. be exclusively used in a preparation method for the Chinese powder medicine for the treatment of bady's diaper dermatitis as claimed in claim 1, comprise the steps: to take the Radix Et Rhizoma Rhei of recipe quantity, Rhizoma Coptidis, Galla Chinensis and dried Alumen, cut into slices respectively, cure, damp eliminating is dry; Dried Radix Et Rhizoma Rhei, Rhizoma Coptidis, Galla Chinensis and dried Alumen are ground to form fine powder respectively, crosses 200 mesh sieves, mixed-powder, and polish, autoclaving, obtained.
4. the preparation method being exclusively used in the Chinese powder medicine for the treatment of bady's diaper dermatitis according to claim 3, is characterized in that: described fine powder is the powder of particle diameter 50 ~ 70 microns.
5. the preparation method being exclusively used in the Chinese powder medicine for the treatment of bady's diaper dermatitis according to claim 3, is characterized in that: described autoclaving is pressure 104.0 ~ 137.3kPa, sterilising temp 121 ~ 126 DEG C.
6. the preparation method being exclusively used in the Chinese powder medicine for the treatment of bady's diaper dermatitis according to claim 4 or 5, is characterized in that: take the Radix Et Rhizoma Rhei of recipe quantity, Rhizoma Coptidis, Galla Chinensis and dried Alumen, cut into slices respectively, cure, carry out damp eliminating drying; Dried Radix Et Rhizoma Rhei, Rhizoma Coptidis, Galla Chinensis and dried Alumen are ground to form respectively the fine powder of particle diameter 60 microns, cross 200 mesh sieves, mixed-powder, and polish, under the pressure and 124 DEG C of temperature of 120.0kPa, carry out sterilizing, obtained.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108671176A (en) * | 2018-07-13 | 2018-10-19 | 黄颖 | A kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash |
| CN110917267A (en) * | 2018-09-20 | 2020-03-27 | 西南医科大学附属中医医院 | Pharmaceutical composition for treating dermatitis and preparation method and application thereof |
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