CN104906466A - Eucalyptus leaf cream and preparation method thereof - Google Patents

Eucalyptus leaf cream and preparation method thereof Download PDF

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CN104906466A
CN104906466A CN201510367377.5A CN201510367377A CN104906466A CN 104906466 A CN104906466 A CN 104906466A CN 201510367377 A CN201510367377 A CN 201510367377A CN 104906466 A CN104906466 A CN 104906466A
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parts
eucalyptus
emulsifiable paste
radix
folium eucalypti
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CN104906466B (en
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朱明芳
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Hunan University of Chinese Medicine
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Abstract

The invention provides a eucalyptus leaf cream comprising the following Chinese medicinal herb raw materials in parts by weight: 10-15 parts of eucalyptus oil, 5-8 parts of rhubarb, 5-8 parts of baical skullcap root, 7-12 parts of bark of Chinese corktree, 10-15 parts of densefruit pittany root-bark, 7-12 parts of glabrous greenbrier rhizome, 3-5 parts of wild chrysanthemum and 8-15 parts of belvedere fruit. All the raw materials of the eucalyptus leaf cream provided by the invention are reasonably compatible, the specific properties and effects of each raw material are brought into full play, the complementary effects among the raw materials are taken into account, the effects are significant, and the eucalyptus leaf cream can condition a human body comprehensively from the intrinsic causes of acnes to achieve the aim of treating both symptoms and root causes and does not cause toxic or side effects, so that the problems that a medicament for treating acnes in the prior art is low in cure rate and relatively big in side effect can be solved.

Description

A kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste and preparation method thereof
Technical field
The present invention relates to a kind of field of Chinese herbal, particularly relate to a kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste and preparation method thereof.
Background technology
Acne is that a kind of pilosebaceous chronic inflammatory skin is sick, is mainly in face, chest and back, more common at adolescence.Acne has various skin damage form, comprise acne, pimple, pustule, tuberosity etc., therefore, therefore acne is all commonly encountered diseases and the frequently-occurring disease of department of dermatologry all the time.The cause of disease of acne is comparatively complicated, and the factors such as modern medicine thinks that the pathogenesis of acne is main and hypersteatosis, pilosebaceous duct block, bacteriological infection and inflammatory reaction are closely related.After adolescing, in human body, the content of androgen particularly testosterone raises rapidly, promotes that sebaceous gland is grown and produces a large amount of sebum.The dyskeratosis of pilosebaceous duct causes catheter blockage, dyssebacia simultaneously, forms horn plug, i.e. micropowder thorn.Multiple-microorganism especially propionibacterium acnes amount reproduction in hair follicle, the lipase decomposition sebum that propionibacterium acnes produces generates free fatty, chemotactic inflammatory cell and medium simultaneously, final induction also exacerbate inflammation reaction.It is long that acne has the course of disease, the feature of easily recurrence, and cause certain pressure to patient's health and psychology, long-standing problem vast teenager.
In recent years, due to environmental pollution increase the weight of, dietary habit change, the multiple factors such as stress increase, the sickness rate of acne is in the trend risen year by year.At present, usually the mode Acne treatment of oral or topical antibiotic, tretinoin is adopted clinically, although said medicine has certain curative effect to Acne treatment, but the limitation of drug use is caused due to its drug resistance and teratogenecity, make it fundamentally cannot cure acne, and excessively use antibiotics medicine that the immunity of human body can be made to reduce gradually, thus health is caused serious harm.Meanwhile, the medicine of current Acne treatment has zest more, injured skin while Acne treatment.
Summary of the invention
The invention provides a kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste and preparation method thereof, low with the cured substance rate solving Acne treatment in prior art, the problem that side effect is larger.
The invention provides a kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the herbal raw material of following parts by weight: eucalyptus oil 10-15 part, Radix Et Rhizoma Rhei 5-8 part, Radix Scutellariae 5-8 part, Cortex Phellodendri 7-12 part, Cortex Dictamni 10-15 part, Rhizoma Smilacis Glabrae 7-12 part, Flos Chrysanthemi Indici 3-5 part and Fructus Kochiae 8-15 part.
Preferably, described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the herbal raw material of following parts by weight: eucalyptus oil 15 parts, Radix Et Rhizoma Rhei 6 parts, Radix Scutellariae 6 parts, Cortex Phellodendri 12 parts, Cortex Dictamni 12 parts, Rhizoma Smilacis Glabrae 7 parts, Flos Chrysanthemi Indici 3 parts and the Fructus Kochiae 10 parts.
The invention provides a kind of preparation method of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, the preparation method of described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the following steps:
S01: take the eucalyptus oil of the parts by weight as described in formula, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri, Cortex Dictamni, Rhizoma Smilacis Glabrae, Flos Chrysanthemi Indici and the Fructus Kochiae;
S02: by described Radix Et Rhizoma Rhei, described Radix Scutellariae, described Cortex Phellodendri, described Cortex Dictamni, described Rhizoma Smilacis Glabrae, described Flos Chrysanthemi Indici and described Fructus Kochiae roguing afterwash;
S03: the described Radix Et Rhizoma Rhei cleaned, described Radix Scutellariae, described Cortex Phellodendri, described Cortex Dictamni, described Rhizoma Smilacis Glabrae, described Flos Chrysanthemi Indici and the described Fructus Kochiae are added suitable quantity of water and decocts 1-3 time, and filter, by concentrated after filtrate mixing, obtains concentrated solution;
S04: by described concentrated solution and described eucalyptus oil mixing simmer down to paste.
The technical scheme that embodiments of the invention provide can comprise following beneficial effect:
Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste provided by the invention comprises following herbal raw material: eucalyptus oil, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri, Cortex Dictamni, Rhizoma Smilacis Glabrae, Flos Chrysanthemi Indici and the Fructus Kochiae, and effect of above herbal raw material is as follows:
Radix Et Rhizoma Rhei: the effect such as removing heat from blood, blood stasis dispelling, removing toxic substances.
Radix Scutellariae: eliminating fire and detoxication, hemostasis, antibacterial.
Cortex Phellodendri: heat clearing and damp drying, pathogenic fire purging remove steaming, detoxification sore treatment, for damp-heat dysentery, jaundice, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever, night sweat, sore swollen toxin, eczema pruritus.
Cortex Dictamni: heat-clearing and toxic substances removing, dispeiling pathogenic wind and removing dampness, killing parasites for relieving itching.
Rhizoma Smilacis Glabrae: removing toxic substances, damp eliminating heat, sharp joint, sore, carbuncle and painful swelling, eczema, impetigo, erysipelas, tinea pedis, dermatitis rhus etc. smelly for syphilis, damp and hot arthralgia, stranguria, leukorrhagia Huang.
Flos Chrysanthemi Indici: heat-clearing and toxic substances removing, cures mainly cold, fever, carbuncle sore tumefacting virus, innominate toxic swelling, eczema, dermatitis, snake bite and insect sting etc.
The Fructus Kochiae: clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching, cures mainly difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.
The invention provides a kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the herbal raw material of following parts by weight: eucalyptus oil 10-15 part, Radix Et Rhizoma Rhei 5-8 part, Radix Scutellariae 5-8 part, Cortex Phellodendri 7-12 part, Cortex Dictamni 10-15 part, Rhizoma Smilacis Glabrae 7-12 part, Flos Chrysanthemi Indici 3-5 part and Fructus Kochiae 8-15 part.All raw materials are pure natural Chinese herbal medicine, do not become containing any chemistry, to human skin action temperature and, the untoward reaction such as have no side effect and irritated, and therapeutic effect is good, instant effect.Because eucalyptus oil, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri, Cortex Dictamni, Rhizoma Smilacis Glabrae, Flos Chrysanthemi Indici and the Fructus Kochiae have the effect such as heat-clearing and toxic substances removing, dispelling wind for relieving itching.Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste provided by the invention, each raw material is through rational compatibility, give full play to each raw material self distinctive performance and effect, take into account complementary action each other, Be very effective, by the inherent cause of disease of acne, human body is nursed one's health in all directions, reaches the object for the treatment of both the principal and secondary aspects of a disease, and have no side effect, the cured substance rate that can solve Acne treatment in prior art is low, the problem that side effect is larger.
Should be understood that, it is only exemplary and explanatory that above general description and details hereinafter describe, and can not limit the present invention.
Accompanying drawing explanation
Fig. 1 is the flow chart of the preparation method of the Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste that the embodiment of the present invention provides.
Detailed description of the invention
Each embodiment in this description all adopts the mode of going forward one by one to describe, between each embodiment identical similar part mutually see, what each embodiment stressed is the difference with other embodiment.
Fig. 1 is the flow chart of the preparation method of a kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste provided in the embodiment of the present invention, contains the basic step preparing Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, and the preparation method of the Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste provided in embodiment is all based on the step shown in Fig. 1.
The eucalyptus oil that the present invention uses is finished product eucalyptus oil, and the content of effective ingredient is 85%.
Embodiment 1
The invention provides a kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the herbal raw material of following parts by weight: eucalyptus oil 15 parts, Radix Et Rhizoma Rhei 6 parts, Radix Scutellariae 6 parts, Cortex Phellodendri 12 parts, Cortex Dictamni 12 parts, Rhizoma Smilacis Glabrae 7 parts, Flos Chrysanthemi Indici 3 parts and the Fructus Kochiae 10 parts.
The invention provides a kind of preparation method of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, the preparation method of described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the following steps:
S101: take eucalyptus oil 15 parts, Radix Et Rhizoma Rhei 6 parts, Radix Scutellariae 6 parts, Cortex Phellodendri 12 parts, Cortex Dictamni 12 parts, Rhizoma Smilacis Glabrae 7 parts, Flos Chrysanthemi Indici 3 parts and the Fructus Kochiae 10 parts;
S102: by described Radix Et Rhizoma Rhei, described Radix Scutellariae, described Cortex Phellodendri, described Cortex Dictamni, described Rhizoma Smilacis Glabrae, described Flos Chrysanthemi Indici and described Fructus Kochiae roguing afterwash;
S103: the described Radix Et Rhizoma Rhei cleaned, described Radix Scutellariae, described Cortex Phellodendri, described Cortex Dictamni, described Rhizoma Smilacis Glabrae, described Flos Chrysanthemi Indici and the described Fructus Kochiae are added suitable quantity of water and decocts 1-3 time, and filter, by concentrated after filtrate mixing, obtains concentrated solution;
S104: by described concentrated solution and described eucalyptus oil mixing simmer down to paste.
Embodiment 2
The invention provides a kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the herbal raw material of following parts by weight: eucalyptus oil 10 parts, Radix Et Rhizoma Rhei 5 parts, Radix Scutellariae 5 parts, Cortex Phellodendri 7 parts, Cortex Dictamni 10 parts, Rhizoma Smilacis Glabrae 7 parts, Flos Chrysanthemi Indici 3 parts and the Fructus Kochiae 8 parts.
Embodiment 3
The invention provides a kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the herbal raw material of following parts by weight: eucalyptus oil 15 parts, Radix Et Rhizoma Rhei 8 parts, Radix Scutellariae 8 parts, Cortex Phellodendri 12 parts, Cortex Dictamni 15 parts, Rhizoma Smilacis Glabrae 12 parts, Flos Chrysanthemi Indici 5 parts and the Fructus Kochiae 15 parts.
Embodiment 4
The invention provides a kind of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the herbal raw material of following parts by weight: eucalyptus oil 12 parts, Radix Et Rhizoma Rhei 6 parts, Radix Scutellariae 6 parts, Cortex Phellodendri 10 parts, Cortex Dictamni 12 parts, Rhizoma Smilacis Glabrae 10 parts, Flos Chrysanthemi Indici 4 parts and the Fructus Kochiae 10 parts.
Embodiment 2, embodiment 3 are identical with embodiment 1 with the preparation method of the Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste that embodiment 4 provides, and difference is only that the parts by weight of raw material are different, repeats no more here.
Clinical trial
Experimental group:
Experimental subject: patients with acne adds up to 200, wherein patients with mild number is 50, and moderate patient numbers is 100, and severe patient numbers is 50.
Experimental technique: use two courses for the treatment of of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste that the embodiment of the present invention 1 provides, each course for the treatment of is seven days.
Matched group:
Experimental subject: patients with acne adds up to 200, wherein patients with mild number is 50, and moderate patient numbers is 100, and severe patient numbers is 50.
Experimental technique: two courses for the treatment of of external used medicine using existing Acne treatment, each course for the treatment of is seven days.
It should be noted that, in the patient that experimental group and matched group are selected, M-F is identical, and skin skin quality is similar.
Efficacy assessment standard:
Recovery from illness: acne symptom disappears completely, face is as usual, no longer continues medication.
Effective: acne symptom has clear improvement, need continual cure.
Invalid: acne symptom, without improvement, need be treated with other drug.
Experimental result is as shown in table 1.
Table 1: the experimental data of clinical trial
From the clinical laboratory data in table 1, the Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste provided in the embodiment of the present invention 1, has good therapeutic effect to acne, and all have curative effect in various degree for 200 patients with acne, invalid number is 0 people.By the treatment of two courses for the treatment of, 50 patients with mild are all cured, and meanwhile, 83 moderate patients and 35 severe patients also fully recover, and no longer need continual cure.Raw material due to this Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste is pure Chinese herbal medicine, no side effects, from the endogenous cause of ill of curing the disease, controls that it is basic, conditioning emphatically, and therefore, therapeutic effect is good and have no side effect after use.The medicine of the Acne treatment that matched group provides is not good to the therapeutic effect of acne, especially severe acne patient, and in 50 severe patients, invalid number is up to 20 people, and acne symptom, without improvement, need be treated with other drug.The treatment situation of moderate acne patient is also barely satisfactory, only has 57 patients to cure in 100 moderate acne patients.Meanwhile, after the treatment through two courses for the treatment of, the side reactions such as patient has face red and swollen, irritated are used to occur, injured patient's skin.It can thus be appreciated that Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste provided by the invention, by the inherent cause of disease of acne, human body is nursed one's health in all directions, no side effects, reach the object for the treatment of both the principal and secondary aspects of a disease, the cured substance rate that can solve Acne treatment in prior art is low, the problem that side effect is larger.
The clinical test results of the Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste that embodiment 2, embodiment 3 and embodiment 4 provide and the similar of embodiment 1, the clinical effectiveness of embodiment 1 slightly well, no longer describes in detail here.
Above-described embodiment of the present invention, does not form limiting the scope of the present invention.Any amendment done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.

Claims (3)

1. a Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, it is characterized in that, described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the herbal raw material of following parts by weight: eucalyptus oil 10-15 part, Radix Et Rhizoma Rhei 5-8 part, Radix Scutellariae 5-8 part, Cortex Phellodendri 7-12 part, Cortex Dictamni 10-15 part, Rhizoma Smilacis Glabrae 7-12 part, Flos Chrysanthemi Indici 3-5 part and Fructus Kochiae 8-15 part.
2. Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste according to claim 1, it is characterized in that, described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the herbal raw material of following parts by weight: eucalyptus oil 15 parts, Radix Et Rhizoma Rhei 6 parts, Radix Scutellariae 6 parts, Cortex Phellodendri 12 parts, Cortex Dictamni 12 parts, Rhizoma Smilacis Glabrae 7 parts, Flos Chrysanthemi Indici 3 parts and the Fructus Kochiae 10 parts.
3. a preparation method for Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste, for the preparation of Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste as claimed in claim 1 or 2, is characterized in that, the preparation method of described Folium eucalypti globueli (Eucalyptus globulus Labill.) emulsifiable paste comprises the following steps:
S01: take the eucalyptus oil of parts by weight as claimed in claim 1 or 2, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri, Cortex Dictamni, Rhizoma Smilacis Glabrae, Flos Chrysanthemi Indici and the Fructus Kochiae;
S02: by described Radix Et Rhizoma Rhei, described Radix Scutellariae, described Cortex Phellodendri, described Cortex Dictamni, described Rhizoma Smilacis Glabrae, described Flos Chrysanthemi Indici and described Fructus Kochiae roguing afterwash;
S03: the described Radix Et Rhizoma Rhei cleaned, described Radix Scutellariae, described Cortex Phellodendri, described Cortex Dictamni, described Rhizoma Smilacis Glabrae, described Flos Chrysanthemi Indici and the described Fructus Kochiae are added suitable quantity of water and decocts 1-3 time, and filter, by concentrated after filtrate mixing, obtains concentrated solution;
S04: by described concentrated solution and described eucalyptus oil mixing simmer down to paste.
CN201510367377.5A 2015-06-29 2015-06-29 A kind of folium eucalypti emulsifiable paste and preparation method thereof Expired - Fee Related CN104906466B (en)

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CN114404489A (en) * 2018-08-06 2022-04-29 上海萱蕙生物科技有限公司 Spray liquid and preparation method and application thereof
CN115869351A (en) * 2021-09-28 2023-03-31 北京远大九和药业有限公司 Composition containing eucalyptus oil and preparation method and application thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168363A (en) * 2015-10-09 2015-12-23 湖南中医药大学 Pharmaceutic preparation
CN114404489A (en) * 2018-08-06 2022-04-29 上海萱蕙生物科技有限公司 Spray liquid and preparation method and application thereof
CN115869351A (en) * 2021-09-28 2023-03-31 北京远大九和药业有限公司 Composition containing eucalyptus oil and preparation method and application thereof

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