CN106038905A - Narcotic analgesic and preparation method thereof - Google Patents

Narcotic analgesic and preparation method thereof Download PDF

Info

Publication number
CN106038905A
CN106038905A CN201610499980.3A CN201610499980A CN106038905A CN 106038905 A CN106038905 A CN 106038905A CN 201610499980 A CN201610499980 A CN 201610499980A CN 106038905 A CN106038905 A CN 106038905A
Authority
CN
China
Prior art keywords
parts
radix
herba
narcotic analgesic
raw material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610499980.3A
Other languages
Chinese (zh)
Inventor
杨文礼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610499980.3A priority Critical patent/CN106038905A/en
Publication of CN106038905A publication Critical patent/CN106038905A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538—Schizonepeta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/89—Cyperaceae (Sedge family)
    • A61K36/8905—Cyperus (flatsedge)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Insects & Arthropods (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a narcotic analgesic and a preparation method thereof and belongs to the technical field of medicines. Raw materials of effective components of the narcotic analgesic comprise albizia flower, pinellia ternate, cyperus rotundus, stigma croci, primula efarinosa pax, asarum, lindera aggregate, garden balsam stem, rhizoma acori graminei, mint, alangium platanifolium, salviae miltiorrhiza, angelica root, fructus piperis longi, debregeasia salicifolia, schefflera kwangsiensis, chamomile, schizonepeta, dried tangerine or orange peel and madder. The medicinal materials selected for the narcotic analgesic are appropriate in compatibility, traditional Chinese medicine and modern medicine and pharmacology theories can be met, and the narcotic analgesic has the effects of anesthetizing, promoting blood circulation to remove blood stasis as well as diminishing inflammation and stopping pain. Meanwhile, the narcotic analgesic is good in curative effect, high in effect taking speed, convenient to take and safe and reliable, has no toxic or side effect, can be used for rapidly and effectively relieving pain of a patient in a surgery and is low in cost, thereby being worthy of clinically extensive popularization and application.

Description

A kind of narcotic analgesic medicine and preparation method thereof
Technical field
The present invention relates to pharmaceutical technology field, particularly relate to a kind of narcotic analgesic medicine and preparation method thereof.
Background technology
From the point of view of medical angle, anesthesia is meant that and makes patient overall by medicine or additive method or be locally temporarily lost with Sensation, to reach painless purpose, treats offer condition for operative treatment or other medical examination, in clinical operation, especially It is in the operation of local anesthesia, is required for using anesthetics.
At present, the method for the anesthetis such as commonly used injection Western medicine procaine and benefit card or employing conduction block is entered Row anesthesia, or carry out topical anesthesia by pad pasting.These anesthesia methods used now, although there is certain treatment effect Really, but but there is slow curative effect, medical expense is high, toxic and side effects is big shortcoming, not only complex operation, and to anesthetis Consumption have strict requirements, injection deficiency, do not have good anaesthetic effect, injection excess then can be to the brain of human body, god Harmful effect is produced through system.Therefore the development to Chinese medicine class narcotic analgesic medicine is more and more meaningful.
Summary of the invention
For the deficiencies in the prior art, the invention provides a kind of narcotic analgesic medicine and preparation method thereof, have notable Curative effect, and instant effect, taking convenience, safe and reliable advantage.
For realizing object above, the present invention is achieved by the following technical programs:
The invention provides a kind of narcotic analgesic medicine, the raw material of following weight portion be prepared from: Flos Albiziae 20-30 Part, Rhizoma Pinelliae 8-15 part, Rhizoma Cyperi 3-10 part, Stigma Croci 5-10 part, cloud sedge 1-5 part, Herba Asari 2-6 part, Radix Linderae 1-7 part, deep Grass 2-10 part, Rhizoma Acori Graminei 6-10 part, Herba Menthae 6-12 part, Radix Alangii 5-10 part, Radix Salviae Miltiorrhizae 4-10 part, Radix Angelicae Dahuricae 3-8 part, Fructus Piperis Longi 4-8 part, Ramulus et Folium Debregeasiae Edulis 6-10 part, Radix Schefflerae Arboricolae 5-10 part, Flos Matricariae chamomillae 6-12 part, Herba Schizonepetae 4-8 part, Pericarpium Citri Reticulatae 3-7 part, Radix Rubiae 4-10 part；
Its preparation method is:
(1) weighing raw medicinal material described above the most by weight, being ground into mean diameter after processing is 0.1- The mixed powder of the micron particles of 10 μm；
(2) by the ethanol that determining alcohol is 85-95% that mixed powder addition is mixed powder 4-8 times, stirring and dissolving After by ethanol solution under conditions of 4-6 DEG C, stand 30-60 hour and carry out filtration treatment, by filtrate at 60-75 DEG C after filtration Under the conditions of be dried 4-6 hour, obtain dry raw material；
(3) being added in the ethanol mixed liquor with Mel by dry raw material, being configured to the medicinal liquid that concentration is 0.1-0.5g/ml is Can.
Preferably, the raw material of following weight portion it is prepared from: Flos Albiziae 22-28 part, Rhizoma Pinelliae 10-13 part, Rhizoma Cyperi 5-9 Part, Stigma Croci 6-8 part, cloud sedge 2-4 part, Herba Asari 3-6 part, Radix Linderae 2-6 part, Herba speranskiae tuberculatae 3-9 part, Rhizoma Acori Graminei 7-9 part, Herba Menthae 5- 10 parts, Radix Alangii 6-8 part, Radix Salviae Miltiorrhizae 5-8 part, Radix Angelicae Dahuricae 4-7 part, Fructus Piperis Longi 5-7 part, Ramulus et Folium Debregeasiae Edulis 7-9 part, Radix Schefflerae Arboricolae 6-8 part, Flos Matricariae chamomillae 7-11 part, Herba Schizonepetae 5-7 part, Pericarpium Citri Reticulatae 4-6 part, Radix Rubiae 5-9 part.
Preferably, the raw material of following weight portion it is prepared from: Flos Albiziae 23 parts, the Rhizoma Pinelliae 10 parts, Rhizoma Cyperi 5 parts, western red Spend 6 parts, cloud sedge 3 parts, Herba Asari 3 parts, the Radix Linderae 3 parts, Herba speranskiae tuberculatae 4 parts, Rhizoma Acori Graminei 7 parts, Herba Menthae 7 parts, Radix Alangii 6 parts, Radix Salviae Miltiorrhizae 5 Part, the Radix Angelicae Dahuricae 4 parts, Fructus Piperis Longi 5 parts, Ramulus et Folium Debregeasiae Edulis 7 parts, Radix Schefflerae Arboricolae 6 parts, Flos Matricariae chamomillae 6 parts, Herba Schizonepetae 5 parts, Pericarpium Citri Reticulatae 4 parts, 5 parts of Radix Rubiae.
Preferably, the raw material of following weight portion it is prepared from: Flos Albiziae 25 parts, the Rhizoma Pinelliae 12 parts, Rhizoma Cyperi 6 parts, western red Spend 7 parts, cloud sedge 4 parts, Herba Asari 4 parts, the Radix Linderae 4 parts, Herba speranskiae tuberculatae 5 parts, Rhizoma Acori Graminei 8 parts, Herba Menthae 9 parts, Radix Alangii 8 parts, Radix Salviae Miltiorrhizae 6 Part, the Radix Angelicae Dahuricae 5 parts, Fructus Piperis Longi 6 parts, Ramulus et Folium Debregeasiae Edulis 8 parts, Radix Schefflerae Arboricolae 6 parts, Flos Matricariae chamomillae 8 parts, Herba Schizonepetae 5 parts, Pericarpium Citri Reticulatae 4 parts, 8 parts of Radix Rubiae.
Preferably, the described process in preparation method step (1) is that dried processes with squeezing.
Preferably, the described Mel in preparation method step (3) is chrysanthemum honey, and the concentration in mixed liquor is 2- 4g/ml。
In the present invention, effect of each raw material is as follows:
Flos Albiziae: nature and flavor are sweet, flat, Shu Yu, regulate the flow of vital energy, calm the nerves, active, nourish blood, YIN nourishing kidney, clear away heart-fire improving eyesight.
The Rhizoma Pinelliae: main enter taste double enter lung, water of manageing it is wet, lowering the adverse flow of QI, and kind taste damp-phlegm of dispelling；Water is wet goes then spleen strong and sputum From disappearing, inverse gas drops then harmonization of the stomach and feeling of fullness vomiting from only, therefore is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the good medicine of dissolving lump and resolving mass.
Rhizoma Cyperi: hardship pungent, micro-, micro-sweet is flat.Return liver, spleen, tri-jiao channel；Function cures mainly: promoting QI circulation for relieving depression, menstruction regulating and pain relieving；For Stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea pain Warp.
Stigma Croci: sweet in the mouth, property is flat, energy blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens, pain relieving；For treating troubled thoughts pent-up, chest and diaphragm painful abdominal mass is vexed, Spitting blood, typhoid fever is gone mad, and blood stasis is had a pain, measles, traumatic injury etc..
Cloud sedge: bitter in the mouth, pungent, property is put down, is had expelling wind and removing dampness, effect of removing toxic substances and promoting subsidence of swelling；Cure mainly cold, fever, cough, pharynx Larynx swells and ache, toothache, rheumatic arthralgia, hepatitis, dysentery, skin pruritus, venom etc..
Herba Asari: acrid in the mouth, warm in nature, return lung, kidney channel, there is expelling wind and cold pain relieving, effect that warming the lung to resolve fluid-retention is sensible, cure mainly diseases caused by exogenous pathogenic factor Wind and cold, headache, toothache, wind and cold temperature numbness, affection of exogenous wind-cold, in stop lung cold cough with asthma caused by cold fluid-retention.
The Radix Linderae: acrid in the mouth, warm in nature, return lung, kidney channel, promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.
Herba speranskiae tuberculatae: sweet in the mouth, pungent, warm in nature, enter lung, liver two warp, there is expelling wind and removing dampness, effect of removing toxic substances pain relieving, be used for treating Rheumatic arthritis.
Rhizoma Acori Graminei: acrid in the mouth, warm in nature, enter the heart, stomach warp, there is refreshment of having one's ideas straightened out, effect of removing dampness to restore normal function of the stomach, it is used for treating expectorant and covers clear Key, coma is demented, dizzy, and insomnia is forgetful, tinnitus, retention of dampness in middle-JIAO, abdominal distention etc..
Herba Menthae: acrid in the mouth, cool in nature, enter lung meridian, Liver Channel；For anemopyretic cold, epidemic febrile disease from the beginning of, these product are pungent to dissipate, cool with clearly Heat, clear light cool scattered, Herba Menthae has antivirus action, analgesia, itching-relieving action, irritation, antitussive action, bactericidal action, antibacterial work With, effect of relieveing pain and refreshing, headache, migraine and toothache can be alleviated.
Radix Alangii: acrid in the mouth warm in nature, hardship, has expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, effect of scattered silt pain relieving；It is usually used in rheumatism numbness Bitterly, numb limbs and tense tendons, traumatic injury.
Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold, GUIXIN, Liver Channel；Having blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, the merit of removing heat from blood eliminating carbuncle Effect；For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of abdominal mass abdominal mass, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin infection swells Bitterly.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature, enter lung, spleen, stomach warp, there is relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, dampness leukorrhagia stopping, detumescence and apocenosis Effect, cures mainly headache, supraorbital bone pain, toothache, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, skin pruritus due to dryness, scabies etc..
Fructus Piperis Longi: acrid in the mouth, property heat, returns stomach, large intestine channel, has warming spleen and stomach for dispelling cold, effect of therapeutic method to keep the adverse QI flowing downwards pain relieving, cure mainly coldness and pain in the epigastrium, Vomiting singultus, dysentery, headache, toothache, nasal sinusitis etc..
Ramulus et Folium Debregeasiae Edulis: for the branch and leaf of Urticaceae Debregeasia orientalis C. J. Chen platymiscium Debregeasia orientalis C. J. Chen, acrid in the mouth, micro-hardship, cool in nature, there is dispelling wind cough-relieving, heat clearing away Rash, effect of removing stasis to stop bleeding, cure mainly exogenous cough, hemoptysis, acute infantile convulsion wind, measles without adequate eruption, traumatic injury, women's abdomen wraps Block etc..
Radix Schefflerae Arboricolae: mildly bitter flavor is puckery, temperature, there are wind-expelling pain-stopping, relaxing muscles and tendons and activating QI and blood in the collateral function；For trigeminal neuralgia, nervous headache, The disease such as sciatica, rheumatic arthritis and stomach, intestinal, biliary tract pain.
Flos Matricariae chamomillae: anxiety, anxiety, indignation and fear can be alleviated, make people loosen；There is the function of pain relieving simultaneously；Can relax Myalgia, especially because of the nervous pain caused.
Herba Schizonepetae: acrid in the mouth, micro-hardship, property is micro-wet, enters lung, Liver Channel；Cure mainly cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, Measles, carbuncle, skin ulcer scabies, puerperal blood faints.
Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature, return lung, spleen channel；There is regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm.
Radix Rubiae: cold in nature, bitter in the mouth, return Liver Channel；Effect: cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling, cure mainly, traumatic injury, rheumatic arthralgia, Jaundice, carbuncle sore, hemorrhoid are swollen；The antitussive action of Radix Rubiae is relatively strong, eliminates the phlegm, relievings asthma and take second place, and has certain antiinflammation.
The method have the benefit that
Selected by medicine of the present invention, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, plays anesthesia altogether, invigorates blood circulation Blood stasis dispelling, effect of anti-inflammatory analgetic, and good effect, instant effect, taking convenience, safe and reliable, without any side effects, it is possible to quickly The effective misery alleviated in patient's operation, with low cost, wide popularization and application on clinic.The narcotic analgesic medicine of the present invention Preparation method is simply efficient, adds chrysanthemum honey and has the effect of auxiliary of allaying excitement, the curative effect of medicine can be made to maximize to the greatest extent performance, Cost-effective, injecting a medicament into required part during use can play a role, and is suitable in field of medicaments large-scale promotion.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below in conjunction with the enforcement of the present invention Example, is clearly and completely described the technical scheme in the embodiment of the present invention.Based on the embodiment in the present invention, this area The every other embodiment that those of ordinary skill is obtained under not making creative work premise, broadly falls into present invention protection Scope.
Embodiment 1:
A kind of narcotic analgesic medicine, is prepared from by the raw material of following weight portion: 23 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 10 parts of Pericarpium Zanthoxyli, Rhizoma Cyperi 5 Part, Stigma Croci 6 parts, cloud sedge 3 parts, Herba Asari 3 parts, 3 parts of Herba Ephedrae, Herba speranskiae tuberculatae 4 parts, Rhizoma Acori Graminei 7 parts, Herba Menthae 7 parts, 6 parts of Radix Glycyrrhizae, duck Youngster celery 5 parts, the Radix Angelicae Dahuricae 4 parts, Fructus Piperis Longi 5 parts, Ramulus et Folium Debregeasiae Edulis 7 parts, Radix Notoginseng 6 parts, Flos Matricariae chamomillae 6 parts, Herba Schizonepetae 5 parts, Pericarpium Citri Reticulatae 4 parts, 5 parts of Radix Rubiae.
Its preparation method is:
(1) weigh raw medicinal material described above the most by weight, be dried after process processes with squeezing and be ground into Mean diameter is the mixed powder of the micron particles of 0.1-10 μm；
(2) by mixed powder addition be mixed powder 4 times the ethanol that determining alcohol is 85% in, by second after stirring and dissolving Alcoholic solution, under conditions of 4 DEG C, stands and carries out filtration treatment in 30 hours, filtrate is dried under conditions of 60 DEG C 4 little after filtration Time, obtain dry raw material；
(3) dry raw material is added in the ethanol mixed liquor with Mel, is configured to the medicinal liquid that concentration is 0.1g/ml, Wherein Mel is chrysanthemum honey, and concentration is 2g/ml.
Embodiment 2:
A kind of narcotic analgesic medicine, is prepared from by the raw material of following weight portion: 25 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 12 parts of Pericarpium Zanthoxyli, Rhizoma Cyperi 6 Part, Stigma Croci 7 parts, cloud sedge 4 parts, Herba Asari 4 parts, 4 parts of Herba Ephedrae, Herba speranskiae tuberculatae 5 parts, Rhizoma Acori Graminei 8 parts, Herba Menthae 9 parts, 8 parts of Radix Glycyrrhizae, duck Youngster celery 6 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Piperis Longi 6 parts, Ramulus et Folium Debregeasiae Edulis 8 parts, Radix Notoginseng 6 parts, Flos Matricariae chamomillae 8 parts, Herba Schizonepetae 5 parts, Pericarpium Citri Reticulatae 4 parts, 8 parts of Radix Rubiae.
Its preparation method is:
(1) weigh raw medicinal material described above the most by weight, be dried after process processes with squeezing and be ground into Mean diameter is the mixed powder of the micron particles of 0.1-10 μm；
(2) by mixed powder addition be mixed powder 5 times the ethanol that determining alcohol is 85% in, by second after stirring and dissolving Alcoholic solution, under conditions of 5 DEG C, stands and carries out filtration treatment in 40 hours, filtrate is dried under conditions of 65 DEG C 5 little after filtration Time, obtain dry raw material；
(3) dry raw material is added in the ethanol mixed liquor with Mel, is configured to the medicinal liquid that concentration is 0.3g/ml, Wherein Mel is chrysanthemum honey, and concentration is 3g/ml.
Embodiment 3:
A kind of narcotic analgesic medicine, is prepared from by the raw material of following weight portion: 26 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 11 parts of Pericarpium Zanthoxyli, Rhizoma Cyperi 8 Part, Stigma Croci 7 parts, cloud sedge 4 parts, Herba Asari 4 parts, 4 parts of Herba Ephedrae, Herba speranskiae tuberculatae 5 parts, Rhizoma Acori Graminei 8 parts, Herba Menthae 9 parts, 6 parts of Radix Glycyrrhizae, duck Youngster celery 6 parts, the Radix Angelicae Dahuricae 6 parts, Fructus Piperis Longi 6 parts, Ramulus et Folium Debregeasiae Edulis 8 parts, Radix Notoginseng 6 parts, Flos Matricariae chamomillae 8 parts, Herba Schizonepetae 5 parts, Pericarpium Citri Reticulatae 5 parts, 7 parts of Radix Rubiae.
Its preparation method is:
(1) weigh raw medicinal material described above the most by weight, be dried after process processes with squeezing and be ground into Mean diameter is the mixed powder of the micron particles of 0.1-10 μm；
(2) by mixed powder addition be mixed powder 6 times the ethanol that determining alcohol is 85% in, by second after stirring and dissolving Alcoholic solution, under conditions of 5 DEG C, stands and carries out filtration treatment in 40 hours, filtrate is dried under conditions of 60 DEG C 4 little after filtration Time, obtain dry raw material；
(3) dry raw material is added in the ethanol mixed liquor with Mel, is configured to the medicinal liquid that concentration is 0.1g/ml, Wherein Mel is chrysanthemum honey, and concentration is 4g/ml.
Embodiment 4:
A kind of narcotic analgesic medicine, is prepared from by the raw material of following weight portion: 26 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 11 parts of Pericarpium Zanthoxyli, Rhizoma Cyperi 7 Part, Stigma Croci 7 parts, cloud sedge 4 parts, Herba Asari 4 parts, 5 parts of Herba Ephedrae, Herba speranskiae tuberculatae 6 parts, Rhizoma Acori Graminei 9 parts, Herba Menthae 9 parts, 8 parts of Radix Glycyrrhizae, duck Youngster celery 7 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Piperis Longi 6 parts, Ramulus et Folium Debregeasiae Edulis 8 parts, Radix Notoginseng 7 parts, Flos Matricariae chamomillae 8 parts, Herba Schizonepetae 7 parts, Pericarpium Citri Reticulatae 4 parts, 8 parts of Radix Rubiae.
Its preparation method is:
(1) weigh raw medicinal material described above the most by weight, be dried after process processes with squeezing and be ground into Mean diameter is the mixed powder of the micron particles of 0.1-10 μm；
(2) by mixed powder addition be mixed powder 6 times the ethanol that determining alcohol is 85% in, by second after stirring and dissolving Alcoholic solution, under conditions of 6 DEG C, stands and carries out filtration treatment in 40 hours, filtrate is dried under conditions of 60 DEG C 5 little after filtration Time, obtain dry raw material；
(3) dry raw material is added in the ethanol mixed liquor with Mel, is configured to the medicinal liquid that concentration is 0.5g/ml, Wherein Mel is chrysanthemum honey, and concentration is 4g/ml.
Embodiment 5:
A kind of narcotic analgesic medicine, is prepared from by the raw material of following weight portion: 27 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 12 parts of Pericarpium Zanthoxyli, Rhizoma Cyperi 6 Part, Stigma Croci 7 parts, cloud sedge 4 parts, Herba Asari 5 parts, 4 parts of Herba Ephedrae, Herba speranskiae tuberculatae 6 parts, Rhizoma Acori Graminei 8 parts, Herba Menthae 9 parts, 8 parts of Radix Glycyrrhizae, duck Youngster celery 6 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Piperis Longi 6 parts, Ramulus et Folium Debregeasiae Edulis 9 parts, Radix Notoginseng 6 parts, Flos Matricariae chamomillae 8 parts, Herba Schizonepetae 5 parts, Pericarpium Citri Reticulatae 5 parts, 8 parts of Radix Rubiae.
Its preparation method is:
(1) weigh raw medicinal material described above the most by weight, be dried after process processes with squeezing and be ground into Mean diameter is the mixed powder of the micron particles of 0.1-10 μm；
(2) by mixed powder addition be mixed powder 6 times the ethanol that determining alcohol is 95% in, by second after stirring and dissolving Alcoholic solution, under conditions of 6 DEG C, stands and carries out filtration treatment in 60 hours, filtrate is dried under conditions of 60 DEG C 4 little after filtration Time, obtain dry raw material；
(3) dry raw material is added in the ethanol mixed liquor with Mel, is configured to the medicinal liquid that concentration is 0.1g/ml, Wherein Mel is chrysanthemum honey, and concentration is 4g/ml.
Embodiment 6:
A kind of narcotic analgesic medicine, is prepared from by the raw material of following weight portion: 24 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 12 parts of Pericarpium Zanthoxyli, Rhizoma Cyperi 6 Part, Stigma Croci 7 parts, cloud sedge 4 parts, Herba Asari 4 parts, 4 parts of Herba Ephedrae, Herba speranskiae tuberculatae 5 parts, Rhizoma Acori Graminei 7 parts, Herba Menthae 9 parts, 8 parts of Radix Glycyrrhizae, duck Youngster celery 6 parts, the Radix Angelicae Dahuricae 4 parts, Fructus Piperis Longi 6 parts, Ramulus et Folium Debregeasiae Edulis 8 parts, Radix Notoginseng 8 parts, Flos Matricariae chamomillae 8 parts, Herba Schizonepetae 6 parts, Pericarpium Citri Reticulatae 6 parts, 8 parts of Radix Rubiae.
Its preparation method is:
(1) weigh raw medicinal material described above the most by weight, be dried after process processes with squeezing and be ground into Mean diameter is the mixed powder of the micron particles of 0.1-10 μm；
(2) by mixed powder addition be mixed powder 6 times the ethanol that determining alcohol is 85% in, by second after stirring and dissolving Alcoholic solution, under conditions of 5 DEG C, stands and carries out filtration treatment in 30 hours, filtrate is dried under conditions of 75 DEG C 5 little after filtration Time, obtain dry raw material；
(3) dry raw material is added in the ethanol mixed liquor with Mel, is configured to the medicinal liquid that concentration is 0.3g/ml, Wherein Mel is chrysanthemum honey, and concentration is 4g/ml.
Embodiment 7:
A kind of narcotic analgesic medicine, is prepared from by the raw material of following weight portion: 28 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 12 parts of Pericarpium Zanthoxyli, Rhizoma Cyperi 6 Part, Stigma Croci 7 parts, cloud sedge 4 parts, Herba Asari 4 parts, 5 parts of Herba Ephedrae, Herba speranskiae tuberculatae 5 parts, Rhizoma Acori Graminei 8 parts, Herba Menthae 9 parts, 8 parts of Radix Glycyrrhizae, duck Youngster celery 6 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Piperis Longi 6 parts, Ramulus et Folium Debregeasiae Edulis 9 parts, Radix Notoginseng 6 parts, Flos Matricariae chamomillae 8 parts, Herba Schizonepetae 7 parts, Pericarpium Citri Reticulatae 4 parts, 9 parts of Radix Rubiae.
Its preparation method is:
(1) weigh raw medicinal material described above the most by weight, be dried after process processes with squeezing and be ground into Mean diameter is the mixed powder of the micron particles of 0.1-10 μm；
(2) by mixed powder addition be mixed powder 8 times the ethanol that determining alcohol is 95% in, by second after stirring and dissolving Alcoholic solution, under conditions of 6 DEG C, stands and carries out filtration treatment in 60 hours, filtrate is dried under conditions of 75 DEG C 6 little after filtration Time, obtain dry raw material；
(3) dry raw material is added in the ethanol mixed liquor with Mel, is configured to the medicinal liquid that concentration is 0.3g/ml, Wherein Mel is chrysanthemum honey, and concentration is 3g/ml.
Embodiment 8:
A kind of narcotic analgesic medicine, is prepared from by the raw material of following weight portion: 28 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 12 parts of Pericarpium Zanthoxyli, Rhizoma Cyperi 6 Part, Stigma Croci 7 parts, cloud sedge 4 parts, Herba Asari 4 parts, 3 parts of Herba Ephedrae, Herba speranskiae tuberculatae 5 parts, Rhizoma Acori Graminei 8 parts, Herba Menthae 9 parts, 8 parts of Radix Glycyrrhizae, duck Youngster celery 6 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Piperis Longi 6 parts, Ramulus et Folium Debregeasiae Edulis 8 parts, Radix Notoginseng 6 parts, Flos Matricariae chamomillae 8 parts, Herba Schizonepetae 5 parts, Pericarpium Citri Reticulatae 5 parts, 8 parts of Radix Rubiae.
Its preparation method is:
(1) weigh raw medicinal material described above the most by weight, be dried after process processes with squeezing and be ground into Mean diameter is the mixed powder of the micron particles of 0.1-10 μm；
(2) by mixed powder addition be mixed powder 6 times the ethanol that determining alcohol is 85% in, by second after stirring and dissolving Alcoholic solution, under conditions of 4 DEG C, stands and carries out filtration treatment in 30 hours, filtrate is dried under conditions of 60 DEG C 6 little after filtration Time, obtain dry raw material；
(3) dry raw material is added in the ethanol mixed liquor with Mel, is configured to the medicinal liquid that concentration is 0.3g/ml, Wherein Mel is chrysanthemum honey, and concentration is 4g/ml.
Toxicity test:
Application mice 40, male and female half and half, body weight 16-20g, carry out acute toxicity test.Mice is randomly divided into two groups, often Organize 20, i.e. matched group and administration group, fasting 12 hours before experiment；(concentration is the medicament prepared by embodiments of the invention 1 4.45g crude drug/ml, maximum concentration) gavage, gavage volume is 2ml/kg (i.e. unit dosage form is 8.9 crude drugs/kg), comparison Group gives normal saline, within one day, is administered once, Continuous Observation 14 days after administration, and record mice toxic reaction and dead Die number.
Test result indicate that: compare with matched group, after administration, mice has no notable difference, tests Continuous Observation 14 days, little Mus overall health of patients, diet, drinking-water, body weight increase the most normal.Chinese medicine of the present invention to the hair of mice, behavior, defecation, body weight, The indexs such as organ weights, hemogram, hepatic and renal function, blood glucose, blood fat all have no significant effect, internal organs naked eyes do not find difference change and Histological indications shows, after medication 16 weeks and drug withdrawal 4 weeks, Organs of Mice is all without substantially changing.Chinese medicine of the present invention is described Anaesthetic is little to toxicity after mice long-term prescription, does not also have difference reaction, application safety after drug withdrawal.
Clinical case:
Case selection:
Take and derive from dental patients 120 example in February ,-2016 in May, 2015, male 60 examples, female 60 example, age 18-41 year, outward Wound or odontopathy cause agomphiasis 38 example, residual root of the tooth 44 example, impacted wisdom tooth 38 example.
Anesthesia:
The anaesthetic of present invention tweezers clamping cotton balls dipping the present embodiment 1 is smeared in affected part for several times, and about 1-3min checks During illing skin tissue analgesia, can perform the operation；
Above-mentioned dental patients: periodontal routine disinfection, dip in tweezers clamping cotton balls in being applied in this periodontal pocket of having tooth pulled out and In cavities, about 1-3min, when checking periodontal tissue's analgesia, can implement exodontia.
The standard of curative effect evaluation:
Effective: painless or pain is the least in art, without oozing of blood after postoperative 2-8min, edge of wound shrinks, and postoperative nothing occurs together Inflammation, recovers sensation in postoperative 2-3h；
Effective: without obvious pain in art, a little oozing of blood seen from postoperative 2-8min naked eyes, edge of wound is without substantially shrinking, postoperative Without accompanying inflammation, in postoperative 2-3h, recover sensation；
Invalid: to have obvious pain or hurt like hell in art, after postoperative 8min, naked eyes are shown in the most hemorrhage, or simultaneously Produce accompanying inflammation.
Therapeutic outcome:
Table 1 dental patients postoperative anaesthetic effect statistics example (%)
Patient profiles Sum Effective Effectively Invalid Effective percentage
Agomphiasis 38 34 4 0 100%
Residual root of the tooth 44 39 3 2 95.4%
Impacted wisdom tooth 38 34 4 0 100%
According to the data of table 1, the present invention is for the medicine of narcotic analgesic, and analgesic hemostatic is effective, instant effect, through art Latter 1 week reviewing statistics, postoperative without infecting and comparatively fast recovering sensation, have no adverse reaction.
Above example only in order to technical scheme to be described, is not intended to limit；Although with reference to previous embodiment The present invention is described in detail, it will be understood by those within the art that: it still can be to aforementioned each enforcement Technical scheme described in example is modified, or wherein portion of techniques feature is carried out equivalent；And these amendment or Replace, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.

Claims (6)

1. a narcotic analgesic medicine, it is characterised in that be prepared from by the raw material of following weight portion: Flos Albiziae 20-30 part, half Summer 8-15 part, Rhizoma Cyperi 3-10 part, Stigma Croci 5-10 part, cloud sedge 1-5 part, Herba Asari 2-6 part, Radix Linderae 1-7 part, Herba speranskiae tuberculatae 2-10 Part, Rhizoma Acori Graminei 6-10 part, Herba Menthae 6-12 part, Radix Alangii 5-10 part, Radix Salviae Miltiorrhizae 4-10 part, Radix Angelicae Dahuricae 3-8 part, Fructus Piperis Longi 4-8 part, Ramulus et Folium Debregeasiae Edulis 6-10 part, Radix Schefflerae Arboricolae 5-10 part, Flos Matricariae chamomillae 6-12 part, Herba Schizonepetae 4-8 part, Pericarpium Citri Reticulatae 3-7 part, Radix Rubiae 4-10 part；
Its preparation method is:
(1) weighing raw medicinal material described above the most by weight, being ground into mean diameter after processing is 0.1-10 μm The mixed powder of micron particles；
(2) by the ethanol that determining alcohol is 85-95% that mixed powder addition is mixed powder 4-8 times, will after stirring and dissolving Ethanol solution, under conditions of 4-6 DEG C, stands 30-60 hour and carries out filtration treatment, by filtrate the condition of 60-75 DEG C after filtration Under be dried 4-6 hour, obtain dry raw material；
(3) dry raw material is added in the ethanol mixed liquor with Mel, be configured to the medicinal liquid that concentration is 0.1-0.5g/ml.
2. narcotic analgesic medicine as claimed in claim 1, it is characterised in that be prepared from by the raw material of following weight portion: close Joyous flower 22-28 part, Rhizoma Pinelliae 10-13 part, Rhizoma Cyperi 5-9 part, Stigma Croci 6-8 part, cloud sedge 2-4 part, Herba Asari 3-6 part, Radix Linderae 2-6 Part, Herba speranskiae tuberculatae 3-9 part, Rhizoma Acori Graminei 7-9 part, Herba Menthae 5-10 part, Radix Alangii 6-8 part, Radix Salviae Miltiorrhizae 5-8 part, Radix Angelicae Dahuricae 4-7 part, Fructus Piperis Longi 5-7 Part, Ramulus et Folium Debregeasiae Edulis 7-9 part, Radix Schefflerae Arboricolae 6-8 part, Flos Matricariae chamomillae 7-11 part, Herba Schizonepetae 5-7 part, Pericarpium Citri Reticulatae 4-6 part, Radix Rubiae 5-9 part.
3. narcotic analgesic medicine as claimed in claim 2, it is characterised in that be prepared from by the raw material of following weight portion: close Vigorously spend 23 parts, the Rhizoma Pinelliae 10 parts, Rhizoma Cyperi 5 parts, Stigma Croci 6 parts, cloud sedge 3 parts, Herba Asari 3 parts, the Radix Linderae 3 parts, Herba speranskiae tuberculatae 4 parts, stone Rhizoma Acori Graminei 7 parts, Herba Menthae 7 parts, Radix Alangii 6 parts, Radix Salviae Miltiorrhizae 5 parts, the Radix Angelicae Dahuricae 4 parts, Fructus Piperis Longi 5 parts, Ramulus et Folium Debregeasiae Edulis 7 parts, Radix Schefflerae Arboricolae 6 parts, Flos Matricariae chamomillae 6 Part, Herba Schizonepetae 5 parts, Pericarpium Citri Reticulatae 4 parts, 5 parts of Radix Rubiae.
4. narcotic analgesic medicine as claimed in claim 2, it is characterised in that be prepared from by the raw material of following weight portion: close Vigorously spend 25 parts, the Rhizoma Pinelliae 12 parts, Rhizoma Cyperi 6 parts, Stigma Croci 7 parts, cloud sedge 4 parts, Herba Asari 4 parts, the Radix Linderae 4 parts, Herba speranskiae tuberculatae 5 parts, stone Rhizoma Acori Graminei 8 parts, Herba Menthae 9 parts, Radix Alangii 8 parts, Radix Salviae Miltiorrhizae 6 parts, the Radix Angelicae Dahuricae 5 parts, Fructus Piperis Longi 6 parts, Ramulus et Folium Debregeasiae Edulis 8 parts, Radix Schefflerae Arboricolae 6 parts, Flos Matricariae chamomillae 8 Part, Herba Schizonepetae 5 parts, Pericarpium Citri Reticulatae 4 parts, 8 parts of Radix Rubiae.
5. narcotic analgesic medicine as claimed in claim 1, it is characterised in that the described process in preparation method step (1) Process with squeezing for dried.
6. narcotic analgesic medicine as claimed in claim 1, it is characterised in that the described Mel in preparation method step (3) For chrysanthemum honey, the concentration in mixed liquor is 2-4g/ml.
CN201610499980.3A 2016-06-28 2016-06-28 Narcotic analgesic and preparation method thereof Pending CN106038905A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610499980.3A CN106038905A (en) 2016-06-28 2016-06-28 Narcotic analgesic and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610499980.3A CN106038905A (en) 2016-06-28 2016-06-28 Narcotic analgesic and preparation method thereof

Publications (1)

Publication Number Publication Date
CN106038905A true CN106038905A (en) 2016-10-26

Family

ID=57200259

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610499980.3A Pending CN106038905A (en) 2016-06-28 2016-06-28 Narcotic analgesic and preparation method thereof

Country Status (1)

Country Link
CN (1) CN106038905A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107441280A (en) * 2017-09-06 2017-12-08 王维维 A kind of compound Chinese medicine for treating constipation and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107441280A (en) * 2017-09-06 2017-12-08 王维维 A kind of compound Chinese medicine for treating constipation and preparation method thereof

Similar Documents

Publication Publication Date Title
CN103405596B (en) A kind of Chinese medicine for the treatment of sinusitis
CN103341184B (en) Ultrasonic coupling agent and preparation method thereof
CN103550517B (en) A kind of medicine of Hepatoma therapy
CN102205026B (en) Chinese medicinal composition for treating children chronic sinusitis and preparation method thereof
CN103565929B (en) Traditional Chinese medicine combination for treating heart blood deficiency type night sweat
CN101953930B (en) Externally-applied traditional Chinese medicine for treating tinea capitis
CN106038905A (en) Narcotic analgesic and preparation method thereof
CN104095947A (en) Traditional Chinese medicine preparation for treating scapulohumeral periarthritis
CN103893701B (en) A kind of Chinese medicine composition alleviating patients suffering from postoperative pain and promote wound healing
CN102579607B (en) Chinese medicine composition for treating acne
CN102631426A (en) Traditional Chinese medicine composition for treating anaphylactoid purpura
CN105327285A (en) Medicine used for treating antral gastritis
CN103071142B (en) Quick-acting external patch for tracheitis
CN105770847A (en) Traditional Chinese medicine composition for relieving or treating joint swelling and pain and preparation method and application of traditional Chinese medicine composition
CN105194165B (en) Traditional Chinese medicine used for treating infection of urinary system and preparation method thereof
CN102940806B (en) Chinese medicinal composition for treating hyperlipidemia
CN102366591B (en) Chinese herbal medicinal wine for treating rheumatoid and rheumatoid arthritis and its preparation method
CN105106727A (en) Traditional Chinese medicine composition for treating liver-fire attacking lung type hemoptysis
CN105031180A (en) Traditional Chinese medicine preparation for treating fever and preparation method thereof
CN104367733A (en) Traditional Chinese medicine anesthetic for tooth pulling surgery and preparation method thereof
CN104771498A (en) Traditional Chinese medicine composition for treating mumps caused by accumulated toxic heat
CN110721229A (en) Formula essential oil for treating hyperplasia of mammary glands
CN104524331B (en) Prevent the drug of mumps
CN104606406A (en) External traditional Chinese medicine unguent for preventing allergic rhinitis and preparation method thereof
CN103690815A (en) Traditional Chinese medicinal prescription for treating cold

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20161026