CN103071142B - Quick-acting external patch for tracheitis - Google Patents

Quick-acting external patch for tracheitis Download PDF

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CN103071142B
CN103071142B CN201310060010.XA CN201310060010A CN103071142B CN 103071142 B CN103071142 B CN 103071142B CN 201310060010 A CN201310060010 A CN 201310060010A CN 103071142 B CN103071142 B CN 103071142B
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external patch
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栗明峰
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Abstract

The invention belongs to the technical field of traditional Chinese medicines and relates to a quick-acting external patch for tracheitis. The quick-acting external patch is prepared from a first group of traditional Chinese medicine liquid A, a second group of traditional Chinese medicinal powder B and a third group of medicinal powder C. The quick-acting external patch disclosed by the invention is prepared by combining a hereditary secret formula of an inventor with clinical experience for many years. The quick-acting external patch takes effect by combining various traditional Chinese medicines for comprehensive treating, so that effective components of the medicines penetrats into focus by a mode of combining two actions of effectively stimulating acupuncture points and skin absorption, so as to improve inflammation of lesion positions and achieve the efficacies of strengthening the body resistance to eliminate pathogenic factors, clearing away heat and toxic material, preventing phlegm from forming and stopping coughing, calming down asthma and relieving spasm, reducing swelling and alleviating pain, and clearing throat. In addition, the quick-acting external patch has the advantages of quick response, short treatment course, high cure rate and low expense. The quick-acting external patch has unique curative efficacies on pediatric pertussis, bronchitis, respiratory infection, trachitis, pneumonia, cough caused by cold sequelae and the like.

Description

A kind of quick-acting tracheitis external patchs
Technical field
The invention belongs to technical field of Chinese medicines, particularly a kind of quick-acting tracheitis external patch.
Background technology
Medically, infantile bronchitis means that bronchus is inflamed; pathological changes mainly occurs in the tiny bronchus of pulmonary; namely capillary bronchus; normally by common cold; the complication that the viral infections such as influenza cause, due to also may being infected by antibacterial, is the common a kind of acute upper respiratory tract infection of children's.Taking fever, aversion to cold, headache, dry pharynx, cough, expectoration as main clinical manifestation symptom.The method that doctor trained in Western medicine conventionally adopts is antibiotic therapy, and Time of Administration is long can form drug resistance, and the Chinese patent medicine occurring on market is as children's's oral liquid for clearing away lung-heat, declare pectoral syrup, " Xiaoer Xiaoji Zhike " Oral Liquor clearly " etc., treat slower.The cough with asthma cream that has occurred in recent years external treatment, need to be affixed on breast, and acupuncture point (TIANTU acupoint, quiver middle cave, the FEIYU acupoint) shortcoming of bronchus areal area, back is that the acupuncture point of pasting is many, be difficult for grasping, inconvenience, child need to undress and could all post winter, easily suffered from cold.
Summary of the invention
The object of this invention is to provide a kind of instant effect, short treating period, cure rate high, stick acupuncture point few, easily grasp the quick-acting tracheitis external patchs at acupuncture point.
For realizing object of the present invention, existing according to following technical scheme.A kind of quick-acting tracheitis external patchs, it is characterized in that: it is to be made up of first group of Chinese medicinal liquor A, second group of Chinese medicine powder B, the 3rd group of medicated powder C, and wherein the each component weight portion proportioning of first group of Chinese medicinal liquor A is: 12-19 grams of Rhizoma Atractylodis, 5-9 grams of Pericarpium Citri Reticulataes, 10-12 grams of Cortex Magnoliae Officinalis(processed with ginger), 15-20 grams of the Radixs Angelicae Dahuricae, 15-20 grams, Poria, 5-9 grams of Pericarpium Arecae, 10-12 grams of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 1-5 grams of Radix Glycyrrhizae extractum, 1-2 grams of patchouli oils, 1-2 grams of Folium perillae acutae oils;
The each component weight portion proportioning of second group of Chinese medicine powder B is: each 5-8 grams of Ramulus Cinnamomi, Os Draconis, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Glycyrrhizae Preparata, Concha Ostreae, Rhizoma Coptidis, Rhizoma Pinelliae Preparatum, Pericarpium Trichosanthis, Arisaema Cum Bile, Radix Platycodonis, Herba Ephedrae, stir-baked SEMEN ARMENIACAE AMARUM;
The each component weight portion proportioning of the 3rd group of medicated powder C is: 1-2 grams of FUFANG GANCAO PIAN, 1-2 grams of aminophyllines, 1.5-3 grams of promethazines, 1.5-3 grams of raceanisodamine sheets.
The preparation method of the quick-acting tracheitis external patchs of the present invention is:
Chinese medicinal liquor A produces:
(1), take the each component Chinese medicine of first group of Chinese medicinal liquor A by prescription proportioning for subsequent use;
(2), the Rhizoma Atractylodis that take, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis(processed with ginger), the Radix Angelicae Dahuricae, Poria, Pericarpium Arecae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are added appropriate decocting boil 3 times, 2 hours for the first time, 1 hour for the second time, half an hour for the third time, merging filtrate after filtering respectively, obtains filtrate A, then the Radix Glycyrrhizae extractum taking is smashed to the appropriate decocting in water of rear use melts, then mix with filtrate A, obtain mixed liquid B;
(3), will take patchouli oil, Folium perillae acutae oil appropriate amount of ethanol dissolves to obtain mixed liquor C;
(4), will be through step (2) gained mixed liquid B, merge through the mixed liquor C of step (3) gained, after mixing, water is adjusted in right amount, and makes full dose become 205ml, obtains Chinese medicinal liquor A;
Medicated powder B produces:
(1), take the each component Chinese medicine of second group of medicated powder B by prescription proportioning for subsequent use;
(2), the each component Chinese medicine taking is decocted with water three times, 2 hours for the first time, 1 hour for the second time, half an hour for the third time, merging filtrate after filtering respectively, continued to decoct into thick paste, and cold drying, is ground into fine powder, crosses 150 mesh sieves, mixes, and obtains medicated powder B;
Medicated powder C produces:
(1), take the each component of the 3rd group of medicated powder C by prescription proportioning for subsequent use;
(2), by the each component that takes grind into powder respectively, then mix homogeneously, obtains medicated powder C;
Produced standby Chinese medicinal liquor A is got to 7, medicated powder B with suction pipe and get 0.3 gram, medicated powder C and get 1.1 grams and be uniformly mixed into paste, be then evenly spread out in and on the non-woven fabrics shearing, obtain this quick-acting tracheitis external patchs.
External tracheitis of the present invention pastes according to the theory of Chinese medical discrimination, the evil invasion and attack that are subject to wind, cold, wet, heat due to human body in conjunction with primary disease, cause human lung's trachea, bronchial mucosa inflammatory to change, mucous secretion increases, and occurs cough, coughs up phlegm or with the symptom such as panting.Thereby essential heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, reducing swelling and alleviating pain, the basic rule for the treatment of of relieving cough and resolving phlegm of adopting for the treatment of primary disease, just can receive the radical cure effect for the treatment of both the principal and secondary aspects of a disease, difficult recurrence.
fang Xie:
Rhizoma Atractylodis: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, the edema of having loose bowels, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold.
Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Be used for for fullness in the epigastrium and chest lack of appetite and vomiting, cough with copious phlegm.
Cortex Magnoliae Officinalis(processed with ginger): circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma.Cure mainly: stagnation of QI due to dyspepsia; Abdominal distention constipation; Retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea; Expectorant is stopped up QI rising in reverse order; Fullness in the chest is breathed with cough.
The Radix Angelicae Dahuricae: expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.
Poria: promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming.
Pericarpium Arecae: there is therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, effect of line water detumescence.
Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens): stopping nausea and vomiting by lowering the adverse flow of QI.Be used for vomitting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus.
Radix Glycyrrhizae extractum: can alleviate the stimulation to pharyngeal mucosa, and have the gastrointestinal smooth muscular spasm of alleviation and the effect of desoxycortone sample.For bronchitis, pharyngolaryngitis, the treatment of bronchial asthma.
Patchouli oil: eliminating turbid pathogen with aromatics, appetizing preventing or arresting vomiting, delivers expelling summer-heat.For turbid damp obstructing in middle-JIAO, the vomiting of gastral cavity painful abdominal mass, heat-damp in summer asthenia, uncomfortable in chest not easypro, cold-damp is closed summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.
Folium perillae acutae oil: the cold expelling that induces sweat, relieving QI stagnancy in the stomach.For anemofrigid cold, cough vomiting and nausea, vomiting during pregnancy.
Ramulus Cinnamomi: expelling cold and relieving exterior syndrome; Promoting the flow of QI-blood by warming the meridian; Activating YANG and prormoting functioning of QI.
Os Draconis: tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, and spontaneous sweating, seminal emission stranguria with turbid discharge, tells nosebleed and has blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.
The Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
Rhizoma Zingiberis Recens: be the pungent stomachic of armaticity, have the effects such as warm, excited, diaphoresis, preventing or arresting vomiting, removing toxic substances, warming the lung to relieve cough.
Fructus Jujubae: there is the effects such as tonify deficiency QI invigorating, nourishing blood to tranquillize the mind, invigorating the spleen and regulating the stomach
Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.
Concha Ostreae: suppressing the hyperactive liver to relieve the wind syndrome, has convergence, calmness, removing toxic substances, analgesic effect.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication
Rhizoma Pinelliae Preparatum: drying dampness to eliminate phlegm, for abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache.
Pericarpium Trichosanthis: moistening the lung and resolving phlegm, promoting the circulation of QI the chest stuffiness relieving.
Semen Armeniacae Amarum: relieving cough and asthma: wind and cold or cough due to pathogenic wind-heat, cough caused by dryness-heat, lung-heat cough with asthma.
Arisaema Cum Bile: removing heat-phlegm, dispelling wind and relieving convulsion.For phlegm-heat cough, cough up phlegm yellow thick, middle wind-phlegm fan, demented infantile convulsion.
Radix Platycodonis: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility.Cure mainly cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.
Herba Ephedrae: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For the exterior tightened by pathogenic windcold, the card of breathing with cough due to sluggishness of lung-QI.
FUFANG GANCAO PIAN: have relieving cough and expelling phlegm effect.
Anisodamine: have relaxing smooth muscle, remove vasospasm, improve microcirculatory effect
Aminophylline: the alleviations such as bronchial asthma, asthmatic bronchitis, the obstructive emphysema symptom of panting
Promethazine: as histamine H 1 receptor's antagonist, this medicine can, to the telangiectasis due to antianaphylaxis, reduce the permeability of blood capillary, alleviates bronchial smooth muscle panting due to shrinking
detailed description of the invention:
Take former in following ratio:
The each component of Chinese medicinal liquor A: 12-19 grams of Rhizoma Atractylodis, 5-9 grams of Pericarpium Citri Reticulataes, 10-12 grams of Cortex Magnoliae Officinalis(processed with ginger), 15-20 grams of the Radixs Angelicae Dahuricae, 15-20 grams, Poria, 5-9 grams of Pericarpium Arecae, 10-12 grams of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 1-5 grams of Radix Glycyrrhizae extractum, 1-2 grams of patchouli oils, 1-2 grams of Folium perillae acutae oils;
The each component of Chinese medicine powder B: each 5-8 grams of Ramulus Cinnamomi, Os Draconis, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Glycyrrhizae Preparata, Concha Ostreae, Rhizoma Coptidis, Rhizoma Pinelliae Preparatum, Pericarpium Trichosanthis, Arisaema Cum Bile, Radix Platycodonis, Herba Ephedrae, stir-baked SEMEN ARMENIACAE AMARUM;
The each component of medicated powder C: 1-2 grams of FUFANG GANCAO PIAN, 1-2 grams of aminophyllines, 1.5-3 grams of promethazines, 1.5-3 grams of raceanisodamine sheets.
The preparation method of the quick-acting tracheitis external patchs of the present invention is:
Chinese medicinal liquor A produces:
(1), take the each component Chinese medicine of first group of Chinese medicinal liquor A by prescription proportioning for subsequent use;
(2), the Rhizoma Atractylodis that take, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis(processed with ginger), the Radix Angelicae Dahuricae, Poria, Pericarpium Arecae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are added appropriate decocting boil 3 times, 2 hours for the first time, 1 hour for the second time, half an hour for the third time, merging filtrate after filtering respectively, obtains filtrate A, then the Radix Glycyrrhizae extractum taking is smashed to the appropriate decocting in water of rear use melts, then mix with filtrate A, obtain mixed liquid B;
(3), will take patchouli oil, Folium perillae acutae oil appropriate amount of ethanol dissolves to obtain mixed liquor C;
(4), will be through step (2) gained mixed liquid B, merge through the mixed liquor C of step (3) gained, after mixing, water is adjusted in right amount, and makes full dose become 205ml, obtains Chinese medicinal liquor A;
Medicated powder B produces:
(1), take the each component Chinese medicine of second group of medicated powder B by prescription proportioning for subsequent use;
(2), the each component Chinese medicine taking is decocted with water three times, 2 hours for the first time, 1 hour for the second time, half an hour for the third time, merging filtrate after filtering respectively, continued to decoct into thick paste, and cold drying, is ground into fine powder, crosses 150 mesh sieves, mixes, and obtains medicated powder B;
Medicated powder C produces:
(1), take the each component of the 3rd group of medicated powder C by prescription proportioning for subsequent use;
(2), by the each component that takes grind into powder respectively, then mix homogeneously, obtains medicated powder C;
Produced standby Chinese medicinal liquor A is got to 7, medicated powder B with suction pipe and get 0.3 gram, medicated powder C and get 1.1 grams and be uniformly mixed into paste, be then evenly spread out in and on the non-woven fabrics shearing, obtain this quick-acting tracheitis external patchs.
External patch of the present invention is that inventor is on the basis of secret prescription handed down in the family from generation to generation, in conjunction with oneself summary of clinical experience for many years, obtain through repeatedly testing, therefore this external patch has unique curative effect to obstinate infant tracheitis, it adopts multiple Chinese herbal medicine synergy, comprehensive measure, make the active ingredient of medicine carry out effective stimulus to acupuncture point, the mode that two kinds of effects of absorbing transmission from skin combine is permeated focus, improve diseased region inflammation, play the effect of strengthening vital QI to eliminate pathogenic factors, heat-clearing and toxic substances removing, preventing phlegm from forming and stopping coughing, the spasmolytic of relievining asthma, reducing swelling and alleviating pain, pharynx-clearing throat-benefiting.Its prescription compatibility is proper, rigorous, preparation method uniqueness, and the bronchitis that the external patch of the application of the invention can rapid healing a variety of causes causes, and also instant effect, short treating period, cure rate is high, expense is little.This external patch to infantile pertussis, bronchitis, the infection of suction road, tracheitis,, the cough that causes of pneumonia, flu sequela etc. also has unique curative effect.
The using method of external patch of the present invention is: being affixed on the TIANTU acupoint place at chest place, within 24 hours, changing once, 3-7th is a course for the treatment of.
For showing the therapeutic effect of external patch of the present invention to infant tracheitis, the inventor has carried out clinical observation to 200 routine cases, and existing report is as follows.
1. data and method
1.1 physical data
All infant is all diagnosed according to the standard of the chief editors such as Wu Ruiping " all good fortune Chinese bush cherry practical paidonosologies " (the 6th edition).Collect altogether case 200 examples, in March to 12 at age year old, be divided at random 2 groups.Treatment group 100 examples, wherein male 56 examples, female's 44 examples; Matched group 100 examples, wherein male 52 examples, female's 28 examples.Learn by statistics processing at aspects such as sex, age, the course of disease, the state of an illness for 2 groups, no statistical significance, has comparability (P>0.01).
1.2 Therapeutic Method
2 groups of infants are all suited the medicine to the illness and supporting treatment, and take the circumstances into consideration to give the processing such as oxygen uptake, ultrasonic atomizatio.Antiviral and the antibiotic medicine of routine dose for matched group, viral infection person gives ribavirin or andrographolide, and antibacterial the infected gives erythromycin or azithromycin with penicillins or cephalosporins medicine, mycoplasma infection person.Treatment group is used the present invention quick-acting tracheitis external patchs, within 24 hours, changes once, is affixed on infant TIANTU acupoint, above 2 groups all taking 3~7d as 1 course for the treatment of, observe 1~2 course for the treatment of.
2. result
2.1 criterion of therapeutical effect
Effective: in medication 3~7d, temperature recovery is normal, subjective symptoms and clinical sign disappearance, platelet counting is normal, and rabat is normal or basic recovery is normal.Effective: in medication 3~7d, body temperature declines to some extent, and other symptoms and sign make moderate progress, numeration of leukocyte takes a turn for the better, and chest films showed takes a turn for the better.Invalid: medication is more than 1 week, and symptom is not improved.
2.2 result
Treatment group total effective rate 97.0%, 84.0%, 2 group of matched group total effective rate relatively has statistical significance (P<0.01).Treatment group be better than matched group ( p< 0.01).
Before and after two groups of patient treatments, curative effects are relatively in table 2.1,
Table 2.1 liang group patient curative effect comparison
Group Number of cases Clinical cure Effectively Invalid Total effective rate (%)
Treatment group 100 60 97 3 97.0
Matched group 100 35 84 16 84.0
Note: two groups of curative effect comparisons, difference have statistical significance ( p< 0.01)
The quick-acting tracheitiies of the present invention only need stick acupuncture point of TIANTU acupoint while pasting use, belong to the rule for the treatment of of inner disease outer treat, medicine is by the acupuncture point focus of going directly, eliminate fast symptom, shorten the course of disease, and can reduce antiviral and the infringement of antibiotic medicine to internal organs such as Liver and kidney, eliminate the generation of child's Antibiotic Resistance.Infant is easy to accept, and has solved the thorny problem of child administration decoction difficulty, and satisfactory effect, without obvious adverse reaction, is convenient to clinical expansion and uses.

Claims (2)

1. a quick-acting tracheitis external patch, it is characterized in that: it is to be made up of first group of Chinese medicinal liquor A, second group of Chinese medicine powder B, the 3rd group of medicated powder C, and wherein each material component weight portion proportioning of first group of Chinese medicinal liquor A is: 12-19 grams of Rhizoma Atractylodis, 5-9 grams of Pericarpium Citri Reticulataes, 10-12 grams of Cortex Magnoliae Officinalis(processed with ginger), 15-20 grams of the Radixs Angelicae Dahuricae, 15-20 grams, Poria, 5-9 grams of Pericarpium Arecae, 10-12 grams of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 1-5 grams of Radix Glycyrrhizae extractum, 1-2 grams of patchouli oils, 1-2 grams of Folium perillae acutae oils;
Each material component weight portion proportioning of second group of Chinese medicine powder B is: each 5-8 grams of Ramulus Cinnamomi, Os Draconis, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Glycyrrhizae Preparata, Concha Ostreae, Rhizoma Coptidis, Rhizoma Pinelliae Preparatum, Pericarpium Trichosanthis, Arisaema Cum Bile, Radix Platycodonis, Herba Ephedrae, stir-baked SEMEN ARMENIACAE AMARUM;
Each material component weight portion proportioning of the 3rd group of medicated powder C is: 1-2 grams of FUFANG GANCAO PIAN, 1-2 grams of aminophyllines, 1.5-3 grams of promethazines, 1.5-3 grams of raceanisodamine sheets.
2. the preparation method of a kind of quick-acting tracheitis external patchs according to claim 1, is characterized in that:
Chinese medicinal liquor A produces:
(1), take each material component Chinese medicine of first group of Chinese medicinal liquor A by prescription proportioning for subsequent use;
(2), the Rhizoma Atractylodis that take, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis(processed with ginger), the Radix Angelicae Dahuricae, Poria, Pericarpium Arecae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are added appropriate decocting boil 3 times, 2 hours for the first time, 1 hour for the second time, half an hour for the third time, merging filtrate after filtering respectively, obtains filtrate A, then the Radix Glycyrrhizae extractum taking is smashed to the appropriate decocting in water of rear use melts, then mix with filtrate A, obtain mixed liquid B;
(3), will take patchouli oil, Folium perillae acutae oil appropriate amount of ethanol dissolves to obtain mixed liquor C;
(4), will be through step (2) gained mixed liquid B, merge through the mixed liquor C of step (3) gained, after mixing, water is adjusted in right amount, and makes full dose become 205ml, obtains Chinese medicinal liquor A;
Medicated powder B produces:
(1), take each material component Chinese medicine of second group of medicated powder B by prescription proportioning for subsequent use;
(2), the each component Chinese medicine taking is decocted with water three times, 2 hours for the first time, 1 hour for the second time, half an hour for the third time, merging filtrate after filtering respectively, continued to decoct into thick paste, and cold drying, is ground into fine powder, crosses 150 mesh sieves, mixes, and obtains medicated powder B;
Medicated powder C produces:
(1), take each material component of the 3rd group of medicated powder C by prescription proportioning for subsequent use;
(2), by the each component that takes grind into powder respectively, then mix homogeneously, obtains medicated powder C;
Produced Chinese medicinal liquor A is got to 7, medicated powder B with suction pipe and get 0.3 gram, medicated powder C and get 1.1 grams and be uniformly mixed into paste, be then evenly spread out on the non-woven fabrics shearing, obtain this quick-acting tracheitis external patchs.
CN201310060010.XA 2013-02-26 2013-02-26 Quick-acting external patch for tracheitis Active CN103071142B (en)

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CN103393751A (en) * 2013-07-26 2013-11-20 姚远平 Paste for relieving cough and preparation method thereof
CN109303910A (en) * 2018-11-26 2019-02-05 中国人民解放军第二军医大学第二附属医院 A kind of Chinese medicine composition that treating vomiting and its application

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