CN103893701B - A kind of Chinese medicine composition alleviating patients suffering from postoperative pain and promote wound healing - Google Patents
A kind of Chinese medicine composition alleviating patients suffering from postoperative pain and promote wound healing Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine composition alleviating patients suffering from postoperative pain and promote wound healing, be made up of the raw material of following weight portion: Radix Salviae Miltiorrhizae 7 ~ 15 parts, Rhizoma Corydalis 7 ~ 15 parts, Caulis Spatholobi 25 ~ 35 parts, Herba Houttuyniae 4 ~ 8 parts, Galla Chinensis 4 ~ 8 parts, Herba Asari 2 ~ 4 parts, Radix Zanthoxyli 8 ~ 13 parts, Semen Cuscutae 10 ~ 15 parts, the Radix Astragali 25 ~ 35 parts, Spica Prunellae 25 ~ 35 parts, Radix Bupleuri 25 ~ 35 parts, Radix Angelicae Sinensis 22 ~ 27 parts, 5 ~ 9 parts, Radix Glycyrrhizae, the Radix Linderae 13 ~ 18 parts, 10 ~ 15 parts, the Radix Rehmanniae, Pheretima 15 ~ 25 parts, 6 ~ 10 parts, Flos Carthami, Radix Et Rhizoma Rhei 6 ~ 10 parts, 10 ~ 14 parts, Radix Rehmanniae Preparata, Radix Curcumae 10 ~ 14 parts, Radix Notoginseng 3 ~ 7 parts.The present composition reaches 100% to alleviating patients suffering from postoperative pain effective percentage, and this external enwergy effectively promotes wound healing, and the pain relieving medicine analgesic time in prior art that overcomes is short, need medication repeatedly, easily produce dependent defect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition alleviating patients suffering from postoperative pain and promote wound healing, belong to the field of Chinese medicines.
Background technology
Think that patient's postoperative pain is uncomfortable at present, dare not cough, can not independently stand up, sit up and out-of-bed activity, delay the recovery of gastrointestinal, bladder function thus, extended eating time, have impact on wound healing; Make pulmonary function residual volume, venting QI-blood flow ratio is abnormal, and lung compliance and diaphragmatic function reduce, and respiratory system complication increases.
Simultaneously, postoperative pain is again continuity or the outward manifestation that operation wound causes Systemic stress response, this stress triggers body sympathetic nervous system, adrenal cortex-pituitary-hypothalamic reflection, cause obvious neuroendocrine function disorderly, norepinephrine, epinephrine and adrenocortical hormone are discharged increase, Plasma Glucagon Level increases, insulin sensitivity is significantly reduced, blood glucose increases, but the utilization rate of sugar declines, body is in energy expenditure to be increased, the decomposing state of disorganization.Body hypermetabolism state and autonomic nervous function is hyperfunction makes increased heart rate, heart acting increases; Make blood coagulation and Fibrinolytic System disorder, occur hypercoagulability, thrombosis.
In addition, the tissue injury that operation wound or postoperative pain cause, can the active cell factor or complement system, make the releases such as tumor necrosis factor, interleukin system, Acute radiation reaction, prostaglandin, oxygen-derived free radicals, appropriateness stress be must showing of body defenses reaction, but excessively strong, that the persistent period is long stress, body inflammatory is made to react unbalance, bring out SIRS, cause Organ Dysfunction, even cause Multiple Organ Dysfunction Syndrome to make patient death.
Investigation finds, the surgical patient of about 95% can cause worry, anxiety and uneasiness to fearing of pain, and some then causes nervous, blood pressure to increase.Postoperatively firmly dare not to breathe because of pain, cough and rotate position, secretions is not easily discharged, and causes pulmonary atelectasis and pulmonary infection etc.
For a long time, it is believed that postoperative pain is inevitable, traditional analgesia method also just injects the analgesic drug product such as morphine, pethidine, but it is short to there is analgesia time, needs medication repeatedly, easily produces the shortcomings such as dependency.
Summary of the invention
Technical problem to be solved by this invention is to provide and a kind ofly alleviates patients suffering from postoperative pain and promote the Chinese medicine composition of wound healing, and the pain relieving medicine analgesic time in prior art that overcomes is short, need medication repeatedly, easily produce dependent defect.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of Chinese medicine composition alleviating patients suffering from postoperative pain and promote wound healing, be made up of the raw material of following weight portion: Radix Salviae Miltiorrhizae 7 ~ 15 parts, Rhizoma Corydalis 7 ~ 15 parts, Caulis Spatholobi 25 ~ 35 parts, Herba Houttuyniae 4 ~ 8 parts, Galla Chinensis 4 ~ 8 parts, Herba Asari 2 ~ 4 parts, Radix Zanthoxyli 8 ~ 13 parts, Semen Cuscutae 10 ~ 15 parts, the Radix Astragali 25 ~ 35 parts, Spica Prunellae 25 ~ 35 parts, Radix Bupleuri 25 ~ 35 parts, Radix Angelicae Sinensis 22 ~ 27 parts, 5 ~ 9 parts, Radix Glycyrrhizae, the Radix Linderae 13 ~ 18 parts, 10 ~ 15 parts, the Radix Rehmanniae, Pheretima 15 ~ 25 parts, 6 ~ 10 parts, Flos Carthami, Radix Et Rhizoma Rhei 6 ~ 10 parts, 10 ~ 14 parts, Radix Rehmanniae Preparata, Radix Curcumae 10 ~ 14 parts, Radix Notoginseng 3 ~ 7 parts.
A kind of Chinese medicine composition alleviating patients suffering from postoperative pain and promote wound healing of the present invention, enters
One step is preferably made up of the raw material of following weight portion: Radix Salviae Miltiorrhizae 9 ~ 11 parts, Rhizoma Corydalis 9 ~ 11 parts, Caulis Spatholobi 28 ~ 31 parts, Herba Houttuyniae 5 ~ 6 parts, Galla Chinensis 5 ~ 6 parts, Herba Asari 2 ~ 4 parts, Radix Zanthoxyli 9 ~ 11 parts, Semen Cuscutae 11 ~ 12 parts, the Radix Astragali 29 ~ 31 parts, Spica Prunellae 29 ~ 31 parts, Radix Bupleuri 29 ~ 31 parts, Radix Angelicae Sinensis 24 ~ 26 parts, 5 ~ 7 parts, Radix Glycyrrhizae, the Radix Linderae 14 ~ 16 parts, 10 ~ 13 parts, the Radix Rehmanniae, Pheretima 18 ~ 21 parts, 7 ~ 9 parts, Flos Carthami, Radix Et Rhizoma Rhei 7 ~ 9 parts, 11 ~ 13 parts, Radix Rehmanniae Preparata, Radix Curcumae 11 ~ 13 parts, Radix Notoginseng 4 ~ 6 parts.
A kind of Chinese medicine composition alleviating patients suffering from postoperative pain and promote wound healing of the present invention, enters
One step is preferably made up of the raw material of following weight portion: Radix Salviae Miltiorrhizae 10 parts, Rhizoma Corydalis 10 parts, Caulis Spatholobi 30 parts, Herba Houttuyniae 6 parts, Galla Chinensis 6 parts, Herba Asari 3 parts, Radix Zanthoxyli 10 parts, Semen Cuscutae 12 parts, the Radix Astragali 30 parts, Spica Prunellae 30 parts, Radix Bupleuri 30 parts, Radix Angelicae Sinensis 25 parts, 6 parts, Radix Glycyrrhizae, the Radix Linderae 15 parts, 12 parts, the Radix Rehmanniae, Pheretima 20 parts, 8 parts, Flos Carthami, Radix Et Rhizoma Rhei 8 parts, 12 parts, Radix Rehmanniae Preparata, Radix Curcumae 12 parts, Radix Notoginseng 5 parts.
The crude drug that Chinese medicinal composition preparation of the present invention adopts has following pharmacological effect:
Radix Salviae Miltiorrhizae: nourishing blood and promoting blood circulation, blood stasis dispelling; Calming heart and tranquilizing mind, evacuation of pus, pain relieving; Control angina pectoris, menoxenia, dysmenorrhea, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.
Rhizoma Corydalis: invigorate blood circulation, promoting the circulation of QI, pain relieving.
Caulis Spatholobi: invigorate blood circulation, relaxing muscles and tendons; Control soreness of waist and knee joint, paralysis and numbness, menoxenia.
Herba Houttuyniae: Herba Houttuyniae acrid in the mouth, cold, energy heat-clearing and toxic substances removing, detumescence treat skin ulcer, promoting urination to remove dampness, invigorating the stomach and promoting digestion, with controlling excess-heat, pyretic toxicity, damp, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc.Modern pharmacology experiment shows, this product has the effect such as antibacterial, antiviral, raising immunity of organisms, diuresis.
Galla Chinensis: there is hidroschesis, controlling nocturnal emission with astringent drugs, hemostasis, convergence, antibacterial action.In vitro tests all has significantly antibacterial or bactericidal action to staphylococcus aureus, streptococcus, streptococcus pneumoniae and typhoid fever, paratyphoid fever, dysentery, anthrax, diphtheria, bacillus pyocyaneus etc.
Herba Asari: dispel the wind, cold expelling, row water, has one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.Herba Asari can outer dispersing wind and cold, again can in dispel YIN-cold, pain relieving simultaneously, antitussive effect are better.
Radix Zanthoxyli: there are promoting the circulation of QI to relieve pain, the effects such as promoting blood circulation to remove blood stasis.Can be used for traumatic injury, rheumatic arthralgia, stomachache, toothache, venom etc.
Semen Cuscutae: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity; Use same with Galla Chinensis, can nourishing kidney-yin.
The Radix Astragali: there is enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely; The Radix Astragali can promote the renewal of organism metabolism, resisting fatigue, promotion serum and hepatic protein; Hypoglycemia can be raised and reduce hyperglycemia, the resistance against diseases of body can be improved.
Spica Prunellae: have the effect of letting out clearly liver-fire, mass dissipating and swelling eliminating, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, cooling blood for hemostasis, is applicable to bones and muscles pain, pulmonary tuberculosis, metrorrhagia, leukorrhagia, Fiedeler's disease type hepatitis and bacillary dysentery.
Radix Bupleuri: contained volatile oil (eugenol, acid, r-undecanoic acid lactone and to methoxybenzene diketone) has antipyretic-antalgic effect; Radix Bupleuri also has the function of antiinflammatory, anti-liver injury, Promote immunity.
Radix Glycyrrhizae: Radix Glycyrrhizae property is put down, sweet in the mouth, have removing toxic substances, eliminate the phlegm, pain relieving, the pharmacological action such as spasmolytic.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grows and coughs lung moistening, and emergency is detoxified, and is in harmonious proportion hundred medicines.
The Radix Linderae: Radix Linderae compatibility Radix Angelicae Sinensis Radix Linderae Xin Kaiwentong, promoting QI circulation for relieving depression, dispersing cold for relieving pain, walk edema caused by disorder of QI partially; The two 5 use, plays effect of promoting flow of QI and blood, cold expelling antalgic altogether, is used for the treatment of the diseases such as the dysmenorrhea of QI stagnated by cold blood stasis, puerperal abdonimal pain and colic of cold type.
The Radix Rehmanniae: heat clearing away, promote the production of body fluid, moisturize, laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, regulating menstruation, the incised wound stasis of blood, removing heat from blood, hemostasis.
Pheretima: clear gesture relieving convulsion; Suppressing the hyperactive liver to relieve the wind syndrome; Dredge the meridian passage; To relieving asthma diuresis.Main headache due to hyperactivity of liver-YANG; Apoplectic hemiplegia; Rheumatic arthralgia; Dyspnea and cough due to lung-heat; Urinary obstruction.
Flos Carthami: Flos Carthami has promoting blood circulation to restore menstrual flow, silt pain relieving of dispelling, improve human body immune function, blood pressure lowering, blood fat reducing, increase coronary flow and the effect of the multiclass such as myocardial alimentary blood flow, inhibition thrombosis.
Radix Et Rhizoma Rhei: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation; Tell nosebleed for heat in blood, traumatic injury, external treatment burn due to hot liquid or fire, upper gastrointestinal hemorrhage, cooling blood and removing stasis stops blooding.
Radix Rehmanniae Preparata: Radix Rehmanniae Preparata sweet in the mouth, property are flat and enter blood system, function nourishing YIN and supplementing blood, vital essence replenishing and marrow benifiting; Control deficiency of YIN insufficiency of blood, the hollow institute of brains waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency extremely, pass out semen, metrorrhagia, menoxenia.Radix Angelicae Sinensis and Radix Rehmanniae Preparata are arranged in pairs or groups, and can reach the object of yin nourishing by enriching blood, and be YIN nourishing are again one of effective ways of enriching blood.Secondly, Radix Angelicae Sinensis itself has extraordinary blood circulation-promoting functions, tonify without causing stagnation, and Radix Rehmanniae Preparata and Radix Angelicae Sinensis are combined in one piece and use with outclassing a prescription.
Radix Curcumae: control all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice, the promoting QI circulation for relieving depression of Radix Curcumae energy, promoting blood circulation and stopping pain.
Radix Notoginseng: have another name called Radix Notoginseng, Radix Notoginseng, Herba Senecionis Chrysanthemoidis, blood mountain grass, pouring in June, Sedum spectabile Boreau, there is dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain; Cure mainly spitting of blood, spit blood, have blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling down swells and ache.
Chinese medicine composition of the present invention is to after patients suffering from postoperative administration, 100% is reached to alleviating patients suffering from postoperative pain effective percentage, this external enwergy effectively promotes wound healing, the mutual compatibility of various crude drug can play drug effect together to the full extent, can alleviate patient's pain, and then the pain relieving medicine analgesic time in prior art that overcomes is short, the defect that needs medication repeatedly, easily produce dependency and side effect.
When adopting the present invention to treat, each crude drug taken in above formula puts into marmite, and add appropriate warm water soaking half an hour, then flame enrichment is boiled, then uses slow fire boiling about 30 points, filters medicinal residues, makes decoction, every day two doses, 2 days courses for the treatment of.
Detailed description of the invention
Be described principle of the present invention and feature below in conjunction with embodiment, example, only for explaining the present invention, is not intended to limit scope of the present invention.
embodiment 1
Preparation alleviates patients suffering from postoperative pain and promotes the Chinese medicine composition of wound healing.Formula is: Radix Salviae Miltiorrhizae 7 grams, Rhizoma Corydalis 7 grams, Caulis Spatholobi 30 grams, Herba Houttuyniae 8 grams, Galla Chinensis 8 grams, Herba Asari 2 grams, Radix Zanthoxyli 8 grams, Semen Cuscutae 12 grams, the Radix Astragali 35 grams, Spica Prunellae 35 grams, Radix Bupleuri 25 grams, Radix Angelicae Sinensis 22 grams, 6 grams, Radix Glycyrrhizae, the Radix Linderae 18 grams, 15 grams, the Radix Rehmanniae, Pheretima 15 grams, 6 grams, Flos Carthami, Radix Et Rhizoma Rhei 8 grams, 14 grams, Radix Rehmanniae Preparata, Radix Curcumae 14 grams, Radix Notoginseng 5 grams.
When treating with embodiment 1 formula, each crude drug taken in above formula puts into marmite, and add 1200 grams of warm water soaking half an hours, then flame enrichment is boiled, then uses slow fire boiling about 30 points, filters medicinal residues, makes decoction, every day two doses, 2 days courses for the treatment of.
embodiment 2
Preparation alleviates patients suffering from postoperative pain and promotes the Chinese medicine composition of wound healing.Formula is: Radix Salviae Miltiorrhizae 15 grams, Rhizoma Corydalis 15 grams, Caulis Spatholobi 28 grams, Herba Houttuyniae 4 grams, Galla Chinensis 4 grams, Herba Asari 4 grams, Radix Zanthoxyli 13 grams, Semen Cuscutae 11 grams, the Radix Astragali 25 grams, Spica Prunellae 25 grams, Radix Bupleuri 35 grams, Radix Angelicae Sinensis 27 grams, 5 grams, Radix Glycyrrhizae, the Radix Linderae 13 grams, 10 grams, the Radix Rehmanniae, Pheretima 25 grams, 10 grams, Flos Carthami, Radix Et Rhizoma Rhei 7 grams, 10 grams, Radix Rehmanniae Preparata, Radix Curcumae 10 grams, Radix Notoginseng 7 grams.
When treating with embodiment 2 formula, each crude drug taken in above formula puts into marmite, and add 1000 grams of warm water soaking half an hours, then flame enrichment is boiled, then uses slow fire boiling about 25 points, filters medicinal residues, makes decoction, every day two doses, 2 days courses for the treatment of.
embodiment 3
Preparation alleviates patients suffering from postoperative pain and promotes the Chinese medicine composition of wound healing.Formula is: Radix Salviae Miltiorrhizae 10 grams, Rhizoma Corydalis 10 grams, Caulis Spatholobi 30 grams, Herba Houttuyniae 6 grams, Galla Chinensis 6 grams, Herba Asari 3 grams, Radix Zanthoxyli 10 grams, Semen Cuscutae 12 grams, the Radix Astragali 30 grams, Spica Prunellae 30 grams, Radix Bupleuri 30 grams, Radix Angelicae Sinensis 25 grams, 6 grams, Radix Glycyrrhizae, the Radix Linderae 15 grams, 12 grams, the Radix Rehmanniae, Pheretima 20 grams, 8 grams, Flos Carthami, Radix Et Rhizoma Rhei 8 grams, 12 grams, Radix Rehmanniae Preparata, Radix Curcumae 12 grams, Radix Notoginseng 5 grams.
When treating with embodiment 3 formula, each crude drug taken in above formula puts into marmite, and add 1200 grams of warm water soaking half an hours, then flame enrichment is boiled, then uses slow fire boiling about 30 points, filters medicinal residues, makes decoction, every day two doses, 2 days courses for the treatment of.
embodiment 4
Preparation alleviates patients suffering from postoperative pain and promotes the Chinese medicine composition of wound healing.Formula is: Radix Salviae Miltiorrhizae 11 grams, Rhizoma Corydalis 9 grams, Caulis Spatholobi 35 grams, Herba Houttuyniae 5 grams, Galla Chinensis 5 grams, Herba Asari 3 grams, Radix Zanthoxyli 11 grams, Semen Cuscutae 10 grams, the Radix Astragali 31 grams, Spica Prunellae 29 grams, Radix Bupleuri 30 grams, Radix Angelicae Sinensis 31 grams, 7 grams, Radix Glycyrrhizae, the Radix Linderae 15 grams, 12 grams, the Radix Rehmanniae, Pheretima 18 grams, 8 grams, Flos Carthami, Radix Et Rhizoma Rhei 9 grams, 12 grams, Radix Rehmanniae Preparata, Radix Curcumae 13 grams, Radix Notoginseng 4 grams.
When treating with embodiment 4 formula, each crude drug taken in above formula puts into marmite, and add 1000 grams of warm water soaking half an hours, then flame enrichment is boiled, then uses slow fire boiling about 25 points, filters medicinal residues, makes decoction, every day two doses, 2 days courses for the treatment of.
clinical practice example 1
In patient's totally 20 examples that hospital's random selecting finishes proctectomy, take decoction prepared by the embodiment of the present invention 3, every day two doses (postoperative take potion immediately), 2 days courses for the treatment of.Because postoperative patient pain is strong, need to take medicament of the present invention immediately under the prerequisite not using other analgesia methods, take rear patient pain and all obtain feeling obviously alleviating, effective percentage 100%.Take two days later continuously, pain disappears.
clinical practice example 2
In patient's totally 30 examples that hospital's random selecting finishes debridement and suturing, wherein 20 examples take decoction prepared by the embodiment of the present invention 4, every day two doses (postoperative take potion immediately), 2 days courses for the treatment of.Other 10 examples do not carry out analgesia process.After taking first time medicament, patient's pain all obtains feeling obviously alleviating, effective percentage 100%, and after taking 1 day, pain disappears.Take two days later, the wound suture healing state taking medicament patient of the present invention is good, neoblastic reproduction speed obviously faster than do not process to group.
clinical practice example 3
Patient 20 example after random selecting caesarean operation, the postoperative decoction starting to take the preparation of this embodiment 3 immediately of 10 example, every day two doses (postoperative take potion immediately), 2 days courses for the treatment of, 10 examples are postoperative not to be taken.Patient takes after decoction after 12 hours, and pain significantly alleviates, and patient can stand up voluntarily, and after 24 hours, pain disappears, and patient can stand up easily, rise and retire, and within 8 to 15 days, wound healing is better; 10 examples are not taken, and postoperative 12 hours, patient can not stand up voluntarily, lifts lower limb, and after 48 disappearances, pain alleviates, and within 15 to 20 days, wound healing is better.Take after decoction of the present invention effectively alleviates operation in patients and keenly feel, and significantly shorten wound healing time.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (1)
1. alleviate a Chinese medicine composition for patients suffering from postoperative pain and promotion wound healing, it is characterized in that, be made up of the raw material of following weight portion: Radix Salviae Miltiorrhizae 10 parts, Rhizoma Corydalis 10 parts, Caulis Spatholobi 30 parts, Herba Houttuyniae 6 parts, Galla Chinensis 6 parts, Herba Asari 3 parts, Radix Zanthoxyli 10 parts, Semen Cuscutae 12 parts, the Radix Astragali 30 parts, Spica Prunellae 30 parts, Radix Bupleuri 30 parts, Radix Angelicae Sinensis 25 parts, 6 parts, Radix Glycyrrhizae, the Radix Linderae 15 parts, 12 parts, the Radix Rehmanniae, Pheretima 20 parts, 8 parts, Flos Carthami, Radix Et Rhizoma Rhei 8 parts, 12 parts, Radix Rehmanniae Preparata, Radix Curcumae 12 parts, Radix Notoginseng 5 parts.
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| CN110124088A (en) * | 2019-06-20 | 2019-08-16 | 安徽永亿医疗用品有限公司 | A kind of antibacterial type elastoplast and preparation method thereof that can reduce pain and promote wound healing |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102133323A (en) * | 2011-03-02 | 2011-07-27 | 解连新 | Herbal anesthetic and preparation method thereof |
| CN102846871A (en) * | 2012-08-31 | 2013-01-02 | 杨高林 | Chinese herbal preparation for treating liver-fire ascending type supraorbital neuralgia and preparation method thereof |
| CN103316223A (en) * | 2013-05-10 | 2013-09-25 | 辛国学 | Neck pain treatment capsules |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102133323A (en) * | 2011-03-02 | 2011-07-27 | 解连新 | Herbal anesthetic and preparation method thereof |
| CN102846871A (en) * | 2012-08-31 | 2013-01-02 | 杨高林 | Chinese herbal preparation for treating liver-fire ascending type supraorbital neuralgia and preparation method thereof |
| CN103316223A (en) * | 2013-05-10 | 2013-09-25 | 辛国学 | Neck pain treatment capsules |
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