CN101574510B - Compound szechuan lovage rhizome and safflower soup used for treating thromboangitis obliterans - Google Patents
Compound szechuan lovage rhizome and safflower soup used for treating thromboangitis obliterans Download PDFInfo
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Abstract
The invention relates to the field of medicament formulas, in particular to compound szechuan lovage rhizome and safflower soup used for treating thromboangitis obliterans, which is prepared from the following raw materials by weight percentage: 10 to 12 percent of szechuan lovage rhizome, 10 to 12 percent of safflower, 8 to 10 percent of Chinese angelica, 6 to 8 percent of fresh rehmannia, 5 to 7percent of peach kernel, 5 to 7 percent of bitter orange, 4 to 6 percent of red paeony root, 5 to 9 percent of twotooth achyranthes root, 1 to 3 percent of platycodon root, 2 to 4 percent of cassia b ark, 5 to 8 percent of dried ginger, 5 to 7 percent of gentiana macrophylla, 3 to 5 percent of pubescent angelica root, 2 to 4 percent of divaricate saposhnikovia root, 1 to 3 percent of dahurian angelica root, 1 to 3 percent of Indian buead, 1 to 2 percent of manchurian wildginger and 1 to 3 percent of liquorice. The compound szechuan lovage rhizome and safflower soup has high curative effect on the thromboangitis obliterans, low cost, and no toxic and side effects, has effects of dispelling wind and warming channel to dissipate cold, invigorating blood circulation, reducing swelling and relieving pain, and is suitable for various types of thromboangitis obliterans such as deficiency cold, blood stasis, moist heat, heat toxin, deficiency of qi and blood and the like.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of compound szechuan lovage rhizome and safflower soup that is used for the treatment of thromboangiitis obliterans.
Background technology
As everyone knows, thromboangiitis obliterans be a kind of around in the inflammation of occlusive blood vessel of small artery and accompanying vein, be a segmental and the chronic occlusion disease of showing effect repeatedly, at first invade the medium and small arteriovenous of extremity, see with lower limb more.Clinical manifestation to be to suffer from limb pain even acral necrosis, refers to that toe often comes off to be principal character.Thromboangiitis obliterans belongs to the traditional Chinese medical science " necrosis " category, and etiology and pathogenesis is a congenital defect, or has a liking for the food delicious food, and taste are impaired, and QI and blood is not filled, and it is evil for a long time to feel damp and hot, cold-damp again, causes coagulation of QI-blood, the resistance of the channels stasis of blood.Primary disease starts from tremulous pulse usually, involves vein then, is made progress to near-end by far-end, is segmental and distributes, and blood vessel is more normal between two sections.The onset concealment, make slow progress, repeatedly outbreak back symptom gradually obviously and increase the weight of, main clinical manifestation is afraid of cold for suffering from limb, and skin temperature reduces, pale or cyanosis, suffer from limb paraesthesia and pain, stimulate peripheral nerve because of arising from vessel wall inflammation in early days, avascular pain is caused, i.e. intermittent claudication or rest pain because of obstruction of artery in the back.Long-term chronic ischemia causes the histotrophic nutrition obstacle to change.Severe ischemic person suffers from the limb end and ischemic ulcer or gangrene occur, and the distally arteriopalmus of trouble limb weakens or disappears, and occurs recurrent, migration superficial phlebitis in the pathogenic process.The clinical treatment primary disease focuses on and prevents lesion growth at present, improves and increase lower limb blood circulation, except selecting antiplatelet aggregation and blood vessel dilating medicine for use, the artery blood flow passage is rebuild in Hyperbaric oxygen chamber and operation, medical expense height not only, and cure the symptoms, not the disease, patient's misery increased.
Summary of the invention
Purpose of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, a kind of treatment thromboangiitis curative effect height is provided, cost is low, have no side effect, has the dispelling wind dispelling cold by warming the meridian, the effect of promoting blood circulation and detumescence analgesic is applicable to the compound szechuan lovage rhizome and safflower soup of various thromboangiitis obliteranss such as deficiency and coldness, blood stasis, damp and hot, pyretic toxicity, insufficiency of vital energy and blood.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of compound szechuan lovage rhizome and safflower soup that is used for the treatment of thromboangiitis obliterans, adopt Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Radix Rehmanniae, Semen Persicae, Fructus Aurantii, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Radix Platycodonis, Cortex Cinnamomi, Rhizoma Zingiberis, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Poria, Herba Asari, Radix Glycyrrhizae is a raw material, get and be soaked in water after above-mentioned raw materials is cleaned, decoct remove slag filtrate, it is characterized in that: the raw material composition is by weight percentage: Rhizoma Chuanxiong is 10%~12%, Flos Carthami 10%~12%, Radix Angelicae Sinensis 8%~10%, Radix Rehmanniae 6%~8%, Semen Persicae 5%~7%, Fructus Aurantii 5%~7%, Radix Paeoniae Rubra 4%~6%, Radix Achyranthis Bidentatae 5%~9%, Radix Platycodonis 1%~3%, Cortex Cinnamomi 2%~4%, Rhizoma Zingiberis 5%~8%, Radix Gentianae Macrophyllae 5%~7%, Radix Angelicae Pubescentis 3%~5%, Radix Saposhnikoviae 2%~4%, the Radix Angelicae Dahuricae 1%~3%, Poria 1%~3%, Herba Asari 1%~2%, Radix Glycyrrhizae 1%~3%.
The invention has the beneficial effects as follows, a kind of compound szechuan lovage rhizome and safflower soup that is used for the treatment of thromboangiitis obliterans, treatment thromboangiitis curative effect height, cost is low, have no side effect, have the dispelling wind dispelling cold by warming the meridian, the effect of promoting blood circulation and detumescence analgesic is applicable to various thromboangiitis obliteranss such as deficiency and coldness, blood stasis, damp and hot, pyretic toxicity, insufficiency of vital energy and blood.
The specific embodiment
The invention will be further described below in conjunction with embodiment:
Embodiment 1:
Adopt Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Radix Rehmanniae, Semen Persicae, Fructus Aurantii, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Radix Platycodonis, Cortex Cinnamomi, Rhizoma Zingiberis, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Poria, Herba Asari, Radix Glycyrrhizae 18 flavor Chinese herbal medicine are that feedstock production forms, getting clean every clothes by following component (weight %) is Rhizoma Chuanxiong 11.3, Flos Carthami 11.3, Radix Angelicae Sinensis 9.1, Radix Rehmanniae 7.6, Semen Persicae 6.8, Fructus Aurantii 6.1, Radix Paeoniae Rubra 5.3, Radix Achyranthis Bidentatae 6.8, Radix Platycodonis 2.3, Cortex Cinnamomi 3.8, Rhizoma Zingiberis 7.6, Radix Gentianae Macrophyllae 6.1, Radix Angelicae Pubescentis 4.5, Radix Saposhnikoviae 3.0, the Radix Angelicae Dahuricae 2.3, Poria 2.3, Herba Asari 1.5, Radix Glycyrrhizae 2.3, getting the every clothes gross weight of above-mentioned 18 flavor Chinese herbal medicine is 132 grams, be soaked in the 700-900ml clear water after above-mentioned 18 flavor Chinese herbal medicine are cleaned, soaked 5-7 hour, decoct 90-120 minute with slow fire then, remove slag about filtrate 180ml, medicinal residues add water 300-400ml again, decoct 40-60 minute, remove slag about filtrate 80-120ml, altogether 260-300ml left and right sides medicine juice, promptly make " compound szechuan lovage rhizome and safflower soup ", pack in the aseptic vial, seal bottle cap is standby.Every day, 1 dose of branch 2 times was oral, and each oral 130-150ml on an empty stomach orally disappears to the clinical symptoms sign, and Pi Wen, arteriopalmus are normal, and oral again 10-15 days to consolidate curative effect.
Principal agent Rhizoma Chuanxiong nature,taste and action of the present invention: hot, warm, blood-activating and qi-promoting, the wind pain relieving of loosing.Cure mainly rheumatic arthralgia, menoxenia, amenorrhea stomachache, distending pain in the chest and hypochondrium, angina pectoris, cold, dizziness, headache etc.Chemical constituent: root stock contains volatile oil, cnidium lactone, ferulic acid, volatility oily alkaloid and phenolic substance etc.Pharmacological action: the central nervous system there is inhibitory action, hypnotic, blood vessel dilating brings high blood pressure down, and reduces oxygen consumption and reaches effects such as smooth muscle spasmolysis contractions.Flos Carthami nature,taste and action: suffering, temperature, promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Cure mainly dysmenorrhea, amenorrhea, coronary heart disease, angina pectoris, traumatic injury, blood stasis is had a pain etc.Pharmacological action: Flos Carthami can distend the blood vessels, and persistent hypotensive effect is arranged.Decoct can make the heart shrink and expansion increases, and can make the kidney vasoconstriction, and the kidney volume dwindles.The Radix Angelicae Sinensis nature,taste and action: sweet, hot, warm, tonifying blood and regulating menstruation is moisturized laxation, cures mainly menoxenia, blood deficiency amenorrhea, dysmenorrhea, dysfunctional uterine hemorrhage, chronic pelvic inflammatory disease, headache due to deficiency of blood, constipation, alopecia etc.The Radix Rehmanniae nature,taste and action: sweet, bitter, cold, heat clearing away, promote the production of body fluid, moisturize, removing heat from blood, hemostasis.Cure mainly: fever due to yin deficiency, Tianjin wound is thirsty, laryngopharynx swelling and pain, heat in blood is spitted blood, blood, hematuria is had blood in stool, constipation, macule etc.The Semen Persicae nature,taste and action: bitter, sweet, flat, blood circulation promoting competent silt is moisturized laxation, cures mainly: swelling and pain due to blood stasis, traumatic injury, dysmenorrhea, amenorrhea, dryness of the intestine constipation etc.Fructus Aurantii nature,taste and action: bitter, acid, be slightly cold, dispelling the stagnated QI, row expectorant, loose and amass, disappear painful abdominal mass.Cure mainly that food stagnation expectorant stagnates, distension and fullness of the chest and abdomen, abdominal distention stomachache, gastroptosis, proctoptosis, uterine prolapse etc.Pharmacological action: decoct rabbit is exsomatized and in vivo the uterus significant excitation is all arranged, can make uterine contraction strong, tensity strengthens, and can make gastrointestinal motility shrink that the rhythm and pace of moving things strengthens and strong.The decoct low concentration makes isolated frog heart shrink enhancing, and frog vascular perfusion shows can make the blood vessel slight shrinkage.The Radix Paeoniae Rubra nature,taste and action: bitter, cool, removing heat from blood, invigorate blood circulation reducing swelling and alleviating pain.Cure mainly menoxenia, dysmenorrhea, amenorrhea, abdominal pain due to blood stasis, pain in chest and hypochondrium, carbuncle pain blister and skin infection etc.The Radix Achyranthis Bidentatae nature,taste and action: bitter, acid, flat, give birth to dissipating blood stasis blood, subduing inflammation, processed with wine invigorating the liver and kidney, bone and muscle strengthening.Cure mainly: give birth to controlling laryngopharynx swelling and pain, hypertension, amenorrhea, retention of placenta, carbuncle, traumatic injury.Processed with wine treating the liver kidney deficiency, soreness of waist and knee joint, extremity are unfavorable, rheumatic arthralgia etc.The Radix Platycodonis nature,taste and action: bitter, hot, tepor, lung qi dispersing, cold expelling eliminate the phlegm, evacuation of pus.Cure mainly: the exogenous cough, expectoration is not well, laryngopharynx swelling and pain, abdominal distention uncomfortable in chest, bronchitis, lung abscess, pleuritis etc.Cortex Cinnamomi nature,taste and action: sweet, hot, big heat, warming middle-JIAO YANG invigorating, dispersing cold for relieving pain.Cure mainly: stomach abdomen cold type of pain, deficiency and coldness is had loose bowels, insufficiency of kidney-YANG, the arthralgia due to cold lumbago, lung cold is breathed with cough.Chemical constituent: bark contains volatile oil and tannin, phlegmatic temperament, resin etc.Rhizoma Zingiberis nature,taste and action: hot, temperature, deliver cold expelling, preventing or arresting vomiting, detoxifcation.Cure mainly anemofrigid cold, gastrofrigid vomiting etc.The Radix Gentianae Macrophyllae nature,taste and action: bitter, hot, flat, expelling wind and removing dampness, reducing the asthenic fever.Cure mainly rheumatic arthralgia, tuberculosis humidity, jaundice, headache, toothache and neuralgia etc.Pharmacological action: anti rheumatism action is similar with cortisone, and certain antiallergic and antihistaminic effect are arranged, and capillary permeability is obviously reduced.Analgesic, analgesia is arranged, and decreased heart rate brings high blood pressure down and suppresses anthrax bacillus, staphylococcus aureus, Salmonella paratyphi, dysentery bacterium etc.The Radix Angelicae Pubescentis nature,taste and action: hot, bitter, warm, expelling wind and dampness, dispersing cold for relieving pain.Cure mainly rheumatic arthralgia, soreness of waist and knee joint, headache due to common cold, the carbuncle bleb swells and ache etc.Zoopery confirms analgesia, arthritis are arranged, blood vessel dilating, the effect that brings high blood pressure down.The Radix Saposhnikoviae nature,taste and action: hot, sweet, warm, relieving the exterior syndrome by diaphoresis, expelling wind and removing dampness.Cure mainly vexed, the anemofrigid cold of breast abdomen painful abdominal mass, it is lossless to have a headache, migraine, anemofrigid-damp arthralgia, arthralgia, tetanus etc.Chemical constituent: contain volatile oil, mannitol, aldehydes matter, polysaccharide and organic acid etc.Pharmacological action: the refrigeration function of decoct can be kept more than 2 hours.Radix Angelicae Dahuricae nature,taste and action: hot, warm, expelling pathogenic wind and eliminating dampness, evacuation of pus, granulation promoting pain relieving.Cure mainly: carbuncle furuncle and phyma pain, anemofrigid cold, the forehead headache, sinusitis, toothache, anal fistula is had blood in stool, leucorrhea, burn etc.The Poria nature and flavor are sweet, light, flat, promoting diuresis to eliminate damp pathogen, and the spleen invigorating invigorating middle warmer, mind tranquilizing and the heart calming divides dampness removing heat, inducing diuresis to remove edema.Cure mainly insufficiency of the spleen leading to overabundance of dampness, lack of appetite is uncomfortable in chest, cough due to fluid-retention, palpitation and insomnia, dampheat diarrhea, dysuria etc.Herba Asari nature,taste and action: hot, warm, slightly poisonous.Dispel the wind, cold expelling, pain relieving, warming the lung to eliminate phlegm.Cure mainly: headche due to wind-cold, lung cold cough with asthma, rheumatic arthritis etc.The Radix Glycyrrhizae nature,taste and action: sweet, flat, heat-clearing and toxic substances removing, nourishing the lung to arrest cough, coordinating the actions of various ingredients in a prescription cures mainly laryngopharynx swelling and pain, cough, weakness of the spleen and stomach, stomach, duodenal ulcer, carbuncle furuncle and phyma pain, medicine and alimentary toxicosis etc.18 ingenious prescriptions of Chinese herbal medicine, the mutual synergism of medicine, dispelling cold by warming the meridian, promoting blood circulation to remove obstruction in the collateral, QI invigorating is enriched blood and is aided with blood circulation promoting and blood stasis dispelling, and combined effect has specially good effect in thromboangiitis obliterans.
Embodiment 2:
Adopt Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Radix Rehmanniae, Semen Persicae, Fructus Aurantii, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Radix Platycodonis, Cortex Cinnamomi, Rhizoma Zingiberis, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Poria, Herba Asari, Radix Glycyrrhizae 18 flavor Chinese herbal medicine are that feedstock production forms, getting clean every clothes by following component (weight %) is Rhizoma Chuanxiong 11.9, Flos Carthami 10.7, Radix Angelicae Sinensis 9.6, Radix Rehmanniae 7.1, Semen Persicae 6.6, Fructus Aurantii 6.3, Radix Paeoniae Rubra 5.8, Radix Achyranthis Bidentatae 6.3, Radix Platycodonis 2.6, Cortex Cinnamomi 3.5, Rhizoma Zingiberis 7.3, Radix Gentianae Macrophyllae 6.3, Radix Angelicae Pubescentis 4.2, Radix Saposhnikoviae 3.3, the Radix Angelicae Dahuricae 2.5, Poria 2.1, Herba Asari 1.7, Radix Glycyrrhizae 2.2, getting the every clothes gross weight of above-mentioned 18 flavor Chinese herbal medicine is 132 grams, above-mentioned 18 flavor Chinese herbal medicine are cleaned, adding the 700-900ml clear water soaked 5-7 hour, decoct 90-120 minute with slow fire then, remove slag about filtrate 180ml, medicinal residues add water 300-400ml again, decoct 40-60 minute, remove slag filtrate 80-120ml, altogether 260-300ml left and right sides medicine soup, promptly make " compound szechuan lovage rhizome and safflower soup ", pack in the aseptic vial, seal bottle cap is standby, every day, 1 dose of branch 2 times was oral, each (medicine) being taken before meal 130-150ml.It is oral that Pi Wen, pulse are beaten normally to the disappearance of clinical symptoms sign, and oral again 10-15 days, to consolidate curative effect.
But each raw material of the present invention also blended embodiment of the listed ratio of according to the form below (percentage by weight) is realized.Its processing technique and embodiment 1 identical (the every clothes gross weight of 18 flavor Chinese herbal medicine is 132 grams).
Below in conjunction with my institute, promptly the clinical preliminary test that carries out of Shandong Province Wendeng Central Hospital, Weihai City is done further, is described in detail the present invention:
1, case is selected: this organizes 60 examples, age 21-52 year, is thromboangiitis obliterans, women's 12 examples wherein, male's 48 examples.
2, Therapeutic Method: use the present invention to treat the compound szechuan lovage rhizome and safflower soup of thromboangiitis obliterans, every day, 1 dose of branch 2 times was oral, and each (medicine) being taken before meal 130-150ml, takes 6 courses of treatment at per 10 days courses of treatment.
3, therapeutic effect: cure 55 examples, pathological changes does not continue to make progress 2 examples, invalid 3 examples, and effective percentage is 95%, inefficiency is 5%.
Claims (1)
1. compound szechuan lovage rhizome and safflower soup that is used for the treatment of thromboangiitis obliterans, adopt Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Radix Rehmanniae, Semen Persicae, Fructus Aurantii, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Radix Platycodonis, Cortex Cinnamomi, Rhizoma Zingiberis, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Poria, Herba Asari, Radix Glycyrrhizae is a raw material, get and be soaked in water after above-mentioned raw materials is cleaned, decoct remove slag filtrate, it is characterized in that: raw material is formed and is by weight percentage, Rhizoma Chuanxiong is 10%~12%, Flos Carthami 10%~12%, Radix Angelicae Sinensis 8%~10%, Radix Rehmanniae 6%~8%, Semen Persicae 5%~7%, Fructus Aurantii 5%~7%, Radix Paeoniae Rubra 4%~6%, Radix Achyranthis Bidentatae 5%~9%, Radix Platycodonis 1%~3%, Cortex Cinnamomi 2%~4%, Rhizoma Zingiberis 5%~8%, Radix Gentianae Macrophyllae 5%~7%, Radix Angelicae Pubescentis 3%~5%, Radix Saposhnikoviae 2%~4%, the Radix Angelicae Dahuricae 1%~3%, Poria 1%~3%, Herba Asari 1%~2%, Radix Glycyrrhizae 1%~3%.
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CN102406743B (en) * | 2011-11-23 | 2015-06-24 | 朱法存 | Traditional Chinese preparation for treating cerebral thrombosis |
CN102526387B (en) * | 2012-02-27 | 2014-01-15 | 天津中医药大学 | Medicinal composition for treating early-stage diabetic foot and preparation method thereof |
Citations (2)
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CN1115247A (en) * | 1994-07-18 | 1996-01-24 | 马世发 | Anti-cold symptoms fragrant powder |
CN1181868C (en) * | 2002-08-01 | 2004-12-29 | 李正武 | Chinese medicine prepn for treating obliterans thromboangitis |
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CN1115247A (en) * | 1994-07-18 | 1996-01-24 | 马世发 | Anti-cold symptoms fragrant powder |
CN1181868C (en) * | 2002-08-01 | 2004-12-29 | 李正武 | Chinese medicine prepn for treating obliterans thromboangitis |
Non-Patent Citations (2)
Title |
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贾高锁.中医辨证及通心络治疗血栓闭塞性脉管炎68例疗效观察.《中西医结合心脑血管病杂志》.2005,第3卷(第7期),646-647. * |
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