CN105497856A - Traditional Chinese medicine for treating acra paralysis caused by peripheral nerve injuries due to chemotherapy - Google Patents

Traditional Chinese medicine for treating acra paralysis caused by peripheral nerve injuries due to chemotherapy Download PDF

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CN105497856A
CN105497856A CN201610014781.9A CN201610014781A CN105497856A CN 105497856 A CN105497856 A CN 105497856A CN 201610014781 A CN201610014781 A CN 201610014781A CN 105497856 A CN105497856 A CN 105497856A
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radix
chinese medicine
grams
acra
chemotherapy
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张清
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Shandong Provincial Hospital
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Shandong Provincial Hospital
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Abstract

The invention discloses traditional Chinese medicine for treating acra paralysis caused by peripheral nerve injuries due to chemotherapy. The traditional Chinese medicine is prepared from radix paeoniae alba, ramulus cinnamomi, rhizoma zingiberis recens, rehmannia glutinosa, rhizoma chuanxiong, radix angelica sinensis, radix astragali, Chinese dates, peach kernels, scorpions, bombyx batryticatus, radix codonopsis, poria cocos, semen strychni, radix cocculi trilobi, herbs of bunge indigo, cortex acanthopanacis, caulis spatholobi, radix gentianae macrophyllae, dried bodies of ground beetles and silkworm excrement. Multiple Chinese herbs are used as raw materials and matched scientifically, all the medicinal materials achieve a synergistic effect, and the traditional Chinese medicine has the effects of dredging collaterals to relieve paralysis, nourishing blood and tonifying vital energy, and is short in treatment course, quick in effect display, high in treatment rate, safe, free of toxic and side effects and worthy of popularizing.

Description

The Chinese medicine of the acra paralysis that the Peripheral nerve damage caused for chemotherapy causes
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to the Chinese medicine of the acra paralysis that a kind of Peripheral nerve damage caused for chemotherapy causes.
Background technology
Chemotherapy is that treatment promoted by the medicine being able to disease caused by pathogenic microorganism, parasite, malignant tumor, and these special medicines can killing off tumor cells, is sometimes referred to as cell toxicity medicament.Chemotherapy is an effective means of tumor cooperative therapy, but nearly all chemotherapeutics all can produce detrimental effect to peripheral terminals nerve, patient can occur that acra is benumbed, the symptoms such as acra is insensitive, as Nervous toxicity side reaction in various degree all can appear in vincristine, vincaleucoblastine, vindesine, navelbine etc.The acra paralysis that the Peripheral nerve damage caused for chemotherapy at present causes still does not have good Therapeutic Method.
Summary of the invention
For making up the deficiencies in the prior art, the invention provides the Chinese medicine of the acra paralysis that a kind of evident in efficacy Peripheral nerve damage caused for chemotherapy causes.
The present invention is achieved through the following technical solutions:
The Chinese medicine of the acra paralysis that a kind of Peripheral nerve damage caused for chemotherapy causes, its special character is: the raw material comprising following parts by weight: Radix Paeoniae Alba 8-15, Ramulus Cinnamomi 10-15, Rhizoma Zingiberis Recens 5-9, Radix Rehmanniae Preparata 5-8, Rhizoma Chuanxiong 8-15, Radix Angelicae Sinensis 8-15, Radix Astragali 10-15, Fructus Jujubae 12-15, Semen Persicae 8-15, Scorpio 3-8, Bombyx Batryticatus 4-9, Radix Codonopsis 10-15, Poria 3-7, Semen Strychni 2-6, Radix cocculi laurifolii 8-10, Herba indigoferae bungeanae 5-10, Cortex Acanthopancis 6-9, Caulis Spatholobi 8-12, Radix Gentianae Macrophyllae 8-12, eupolyphaga 3-5, silkworm excrement 10-15.
The Chinese medicine of the acra paralysis that the Peripheral nerve damage caused for chemotherapy of the present invention causes, above-mentioned raw materials basis is continued the raw material adding following parts by weight: Extract Aconiti Radicis sucus 4-8, Herba Saussureae Involueratae 6-12, Fructus Rubi 3-5, Folium rhoeinis 4-7, Flos Carthami 3-6.
The Chinese medicine of the acra paralysis that the Peripheral nerve damage caused for chemotherapy of the present invention causes, the raw material of preferred following parts by weight: the Radix Paeoniae Alba 10, Ramulus Cinnamomi 15, Rhizoma Zingiberis Recens 6, Radix Rehmanniae Preparata 6, Rhizoma Chuanxiong 10, Radix Angelicae Sinensis 10, the Radix Astragali 12, Fructus Jujubae, Semen Persicae 10, Scorpio 5, Bombyx Batryticatus 5, Radix Codonopsis 12, Poria 6, Semen Strychni 4, Radix cocculi laurifolii 9, Herba indigoferae bungeanae 9, Cortex Acanthopancis 8, Caulis Spatholobi 10, Radix Gentianae Macrophyllae 10, eupolyphaga 4, silkworm excrement 12.
In the present invention, the effect of each crude drug is as follows:
The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature.Return liver, spleen channel.Nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, suppressing liver-YANG.For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, has a headache dizzy.
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature.Return lung, the heart, urinary bladder channel.Relieving the exterior syndrome by diaphoresis, dispersing cold for relieving pain, activating YANG and prormoting functioning of QI.For anemofrigid cold, all pain diseases of congealing cold with blood stasis, phlegm retention, syndrome of water-retention, cardiopalmus.
Rhizoma Zingiberis Recens: acrid in the mouth, slightly warm in nature.Return lung, spleen, stomach warp.Induce sweat cold expelling, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, removing toxic substances.Anemofrigid cold, taste sympotoms caused by cold factors, gastrofrigid vomiting, lung cold cough, solving toxin of fish and crab.
Radix Rehmanniae Preparata: sweet in the mouth, tepor.Return liver, kidney channel.To enrich blood yin nourishing, life essence-filling, marrow-benefitting.Can be used for blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, the diseases such as metrorrhagia, diseases such as also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, pass out semen, quench one's thirst.
Rhizoma Chuanxiong: acrid in the mouth, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
The Radix Astragali: sweet in the mouth, tepor.Return lung, spleen, liver, kidney channel.Benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, holder skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer.
Fructus Jujubae: sweet in the mouth is warm in nature.Return taste warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, the mitigation property of medicine.For the treatment of the diseases such as deficiency of spleen-QI and stomach-QI, blood deficiency and yellow complexion, blood deficiency insomnia and dreamful sleep.
Semen Persicae: taste bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.For amenorrhea dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, lung abscess acute appendicitis, injury from falling down, dryness of the intestine constipation, cough and asthma.
Scorpio: acrid in the mouth, flat.Return Liver Channel.Endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.For liver-wind stirring up internally, spasm is twitched, infantile convulsion, middle air port, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Bombyx Batryticatus: salty in the mouth, pungent, property is put down.Return liver, lung, stomach warp.Endogenous wind stopping relieving convulsion, wind-expelling pain-stopping, dissipating phlegm and resolving masses.For liver-wind folder expectorant, infantile convulsion is twitched, acute infantile convulsion, tetanus, middle air port, headache due to pathogenic wind-heat, conjunctival congestion pharyngalgia, rubella pruritus, maxillofacial sore mumps.
Radix Codonopsis: sweet in the mouth is flat.Return spleen, lung meridian.Invigorating middle warmer, QI invigorating, promotes the production of body fluid.Cure mainly weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis.
Poria: sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Semen Strychni: bitter in the mouth, temperature.Return liver, spleen channel.There is removing obstruction in the collateral to relieve pain, the effect of mass dissipating and swelling eliminating.For traumatic injury, fracture swells and ache, rheumatoid arthritis stubborn, paralysis and numbness, skin sore, laryngopharynx swelling and pain.
Radix cocculi laurifolii: acrid in the mouth, hardship, cold in nature.Return bladder, lung meridian.Wind-expelling pain-stopping, row water is swollen clearly, removing toxic substances, blood pressure lowering.For rheumatic arthralgia, neuralgia, oedema due to nephritis, urinary tract infection; External treatment traumatic injury, venom.
Herba indigoferae bungeanae: cool in nature, bitter and puckery flavor is nontoxic.Control wound, toxic swelling, aphtha, ecthyma, spit blood, watery diarrhea.
Cortex Acanthopancis: acrid in the mouth, hardship, warm in nature.Liver, kidney channel.There is wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, the effect of inducing diuresis to remove edema.For Bi condition, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, beriberi.
Caulis Spatholobi: bitter in the mouth, sweet, temperature.Return liver, kidney channel.Blood circulation promoting and enriching, menstruction regulating and pain relieving, relaxing muscles and tendons and activating QI and blood in the collateral.For menoxenia, dysmenorrhea, amenorrhea, rheumatic arthralgia, paralysis and numbness, blood deficiency and yellow complexion.
Radix Gentianae Macrophyllae: acrid in the mouth, hardship, property is put down.Return stomach, liver, gallbladder meridian.There is wind-damp dispelling, clearing away damp-heat, stopping numbness pain, the effect of reducing the asthenic fever.For rheumatic arthralgia, apoplexy and hemiplegia, the contracture of muscle arteries and veins, joint is ached, jaundice due to damp-heat, osteopyrexia and fever, and infantile malnutrition generates heat.
Eupolyphaga: salty in the mouth, cold; Slightly poisonous.Return Liver Channel.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For blood stasis amenorrhea, traumatic injury and lump in the abdomen lump.
Silkworm excrement: sweet in flavor and warm in property.Enter liver, spleen, stomach warp.Dampness is dispeled the wind, regulating the function of the stomach to resolve the turbidity, analgesic therapy of invigorating blood circulation.For diseases such as rheumatic arthralgia, wind syndrome of head, headache, skin pruritus, waist lower limb cold type of pain, stomachache vomiting and diarrhoeas.
Extract Aconiti Radicis sucus: bitter in the mouth, heat, poisonous.Control scrofula tuberculosis, fistula sore swells, wind syndrome of head, migratory arthralgia, crux in abdomen, malaria, hernia.
Herba Saussureae Involueratae: slightly cool in nature, sweet in the mouth.Enter lung kidney channel.Looks improving and the skin nourishing, dredging are regulated the flow of vital energy.Have restore menstrual flow and invigorate blood circulation, the effect such as dispelling cold and removing dampness, hemostasia and detumescence, isostere endotoxin.
Fructus Rubi: sweet in the mouth, acid, warm in nature.Return liver, kidney, urinary bladder channel.Supplementing the kidney to control the nocturnal reducing urination, nourishing the liver to improve visual acuity.For emission and spermatorrhea, enuresis frequent micturition, impotence and premature ejaculation, order is secretly dim-sighted.
Folium rhoeinis: sweet in the mouth, cool heat clearing away, hemostasis, blood stasis removing.Control lung-heat type cough, spit blood, have blood in stool, hematuria, dysentery, traumatic injury.
Flos Carthami: acrid in the mouth, warm in nature.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, injury from falling down, skin infection swells and ache.
The invention has the beneficial effects as follows: the present invention take kinds of traditional Chinese medicines as raw material, scientific compatibility, and synergism between each crude drug, has dredging collateral and open numbness, the effect of the QI invigorating that nourishes blood, short treating period, instant effect, and treatment rate is high, safe without toxic side effect.
Detailed description of the invention
Embodiment 1
Chinese medicine component: the Radix Paeoniae Alba 8 grams, Ramulus Cinnamomi 10 grams, 5 grams, Rhizoma Zingiberis Recens, 5 grams, Radix Rehmanniae Preparata, Rhizoma Chuanxiong 8 grams, Radix Angelicae Sinensis 8 grams, the Radix Astragali 10 grams, 12 grams, Fructus Jujubae, 8 grams, Semen Persicae, Scorpio 3 grams, Bombyx Batryticatus 4 grams, Radix Codonopsis 10 grams, 3 grams, Poria, Semen Strychni 2 grams, Radix cocculi laurifolii 8 grams, Herba indigoferae bungeanae 5 grams, Cortex Acanthopancis 6 grams, Caulis Spatholobi 8 grams, Radix Gentianae Macrophyllae 8 grams, eupolyphaga 3 grams, silkworm excrement 10 grams, Extract Aconiti Radicis sucus 4 grams, Herba Saussureae Involueratae 6 grams, Fructus Rubi 3 grams, Folium rhoeinis 4 grams, 3 grams, Flos Carthami.
Preparation technology: recipe quantity medical material is decocted with water 3 times, collecting decoction.Every day potion, morning and evening service once, 5 days courses for the treatment of.
Embodiment 2
Chinese medicine component: the Radix Paeoniae Alba 10 grams, Ramulus Cinnamomi 15 grams, 6 grams, Rhizoma Zingiberis Recens, 6 grams, Radix Rehmanniae Preparata, Rhizoma Chuanxiong 10 grams, Radix Angelicae Sinensis 10 grams, the Radix Astragali 12 grams, Fructus Jujubae gram, 10 grams, Semen Persicae, Scorpio 5 grams, Bombyx Batryticatus 5 grams, Radix Codonopsis 12 grams, 6 grams, Poria, Semen Strychni 4 grams, Radix cocculi laurifolii 9 grams, Herba indigoferae bungeanae 9 grams, Cortex Acanthopancis 8 grams, Caulis Spatholobi 10 grams, Radix Gentianae Macrophyllae 10 grams, eupolyphaga 4 grams, silkworm excrement 12 grams.
Preparation technology: recipe quantity medical material is decocted with water 3 times, collecting decoction.Every day potion, morning and evening service once, 5 days courses for the treatment of.
Embodiment 3
Chinese medicine component: the Radix Paeoniae Alba 15 grams, Ramulus Cinnamomi 15 grams, 9 grams, Rhizoma Zingiberis Recens, 8 grams, Radix Rehmanniae Preparata, Rhizoma Chuanxiong 15 grams, Radix Angelicae Sinensis 15 grams, the Radix Astragali 15 grams, 15 grams, Fructus Jujubae, 15 grams, Semen Persicae, Scorpio 8 grams, Bombyx Batryticatus 9 grams, Radix Codonopsis 15 grams, 7 grams, Poria, Semen Strychni 6 grams, Radix cocculi laurifolii 10 grams, Herba indigoferae bungeanae 10 grams, Cortex Acanthopancis 9 grams, Caulis Spatholobi 12 grams, Radix Gentianae Macrophyllae 12 grams, eupolyphaga 5 grams, silkworm excrement 15 grams, Extract Aconiti Radicis sucus 8 grams, Herba Saussureae Involueratae 12 grams, Fructus Rubi 5 grams, Folium rhoeinis 7 grams, 6 grams, Flos Carthami.
Preparation technology: recipe quantity medical material is decocted with water 3 times, collecting decoction.Every day potion, morning and evening service once, 5 days courses for the treatment of.
Embodiment 4: clinical observation
(1) physical data
The present inventor carried out clinical observation treatment to 200 routine patients so far in 2013, cured 180 people, and effective 14 people, total effective rate is up to 97%.
(2) Therapeutic Method: every day potion, morning and evening service once, 5 days courses for the treatment of.
(3) efficacy assessment standard
Cure: symptom and sign disappears completely;
Effective: symptom and sign comparatively alleviates;
Invalid: symptom and sign is front without improving with treatment.
(4) model case:
, 43 years old, after chemotherapy, there is palm heel numbness, pruritus, Silent Neuritis erythema and swelling phenomenon, start to take Chinese medicine of the present invention in August, 2013 in Jiang, every day potion, morning and evening service once, 5 days courses for the treatment of, fully recovers after three courses for the treatment of.
Zhao, 69 years old, occur after chemotherapy that finger tip is numb, tendon reflex weakens or disappear, can anesthesia be there is, intersection point, amyotrophy or numbness, orthostatic hypotension in paraesthesia, minority, bladder tension reduction, constipation phenomenon, start to take Chinese medicine of the present invention in May, 2014, every day potion, morning and evening service once, 5 days courses for the treatment of, fully recover after five courses for the treatment of.
, 51 years old, there is numb hand and foot after chemotherapy in Zhang, just as worm row, pale complexion, spontaneous perspiration, shortness of breath and fatigue, drowsiness lazyness speech, easy catching a cold, loose stool, light red tongue, corpulent tongue is large, white and thin fur, weak pulse phenomenon, started to take Chinese medicine of the present invention in January, 2015, every day potion, morning and evening service once, 5 days courses for the treatment of, fully recovers after five courses for the treatment of.

Claims (3)

1. the Chinese medicine of acra paralysis that causes of the Peripheral nerve damage caused for chemotherapy, it is characterized in that: the raw material comprising following parts by weight: Radix Paeoniae Alba 8-15, Ramulus Cinnamomi 10-15, Rhizoma Zingiberis Recens 5-9, Radix Rehmanniae Preparata 5-8, Rhizoma Chuanxiong 8-15, Radix Angelicae Sinensis 8-15, Radix Astragali 10-15, Fructus Jujubae 12-15, Semen Persicae 8-15, Scorpio 3-8, Bombyx Batryticatus 4-9, Radix Codonopsis 10-15, Poria 3-7, Semen Strychni 2-6, Radix cocculi laurifolii 8-10, Herba indigoferae bungeanae 5-10, Cortex Acanthopancis 6-9, Caulis Spatholobi 8-12, Radix Gentianae Macrophyllae 8-12, eupolyphaga 3-5, silkworm excrement 10-15.
2. the Chinese medicine of acra paralysis that causes of the Peripheral nerve damage caused for chemotherapy according to claim 1, is characterized in that: the raw material also comprising following parts by weight: Extract Aconiti Radicis sucus 4-8, Herba Saussureae Involueratae 6-12, Fructus Rubi 3-5, Folium rhoeinis 4-7, Flos Carthami 3-6.
3. the Chinese medicine of acra paralysis that causes of the Peripheral nerve damage caused for chemotherapy according to claim 1, it is characterized in that: the raw material comprising following parts by weight: the Radix Paeoniae Alba 10, Ramulus Cinnamomi 15, Rhizoma Zingiberis Recens 6, Radix Rehmanniae Preparata 6, Rhizoma Chuanxiong 10, Radix Angelicae Sinensis 10, the Radix Astragali 12, Fructus Jujubae, Semen Persicae 10, Scorpio 5, Bombyx Batryticatus 5, Radix Codonopsis 12, Poria 6, Semen Strychni 4, Radix cocculi laurifolii 9, Herba indigoferae bungeanae 9, Cortex Acanthopancis 8, Caulis Spatholobi 10, Radix Gentianae Macrophyllae 10, eupolyphaga 4, silkworm excrement 12.
CN201610014781.9A 2016-01-11 2016-01-11 Traditional Chinese medicine for treating acra paralysis caused by peripheral nerve injuries due to chemotherapy Pending CN105497856A (en)

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CN109223859A (en) * 2018-11-15 2019-01-18 北京大学深圳医院 Pharmaceutical composition, drug and its application

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Publication number Priority date Publication date Assignee Title
CN108686034A (en) * 2018-07-09 2018-10-23 姚大鹏 The Chinese medicine composition and preparation method of bone marrow suppression after a kind of antagonism chemotherapy of tumors
CN108686034B (en) * 2018-07-09 2022-01-28 姚大鹏 Traditional Chinese medicine composition for antagonizing bone marrow suppression after tumor chemotherapy and preparation method thereof
CN109223859A (en) * 2018-11-15 2019-01-18 北京大学深圳医院 Pharmaceutical composition, drug and its application

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