CN105267415A - Traditional Chinese medicine composition for treating osteomyelitis - Google Patents
Traditional Chinese medicine composition for treating osteomyelitis Download PDFInfo
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- CN105267415A CN105267415A CN201510757528.8A CN201510757528A CN105267415A CN 105267415 A CN105267415 A CN 105267415A CN 201510757528 A CN201510757528 A CN 201510757528A CN 105267415 A CN105267415 A CN 105267415A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating osteomyelitis. The traditional Chinese medicine composition comprises, by weight, 13-17 parts of radix rehmanniae preparata, 10-14 parts of angelica sinensis, 9-11 parts of fructus psoraleae, 13-17 parts of radix astragali, 14-16 parts of poria cocos, 11-13 parts of rhizoma drynariae, 14-16 parts of radix pseudostellariae, 13-17 parts of rhizoma chuanxiong, 9-11 parts of radix clematidis, 10-14 parts of achyranthes bidentata, 8-12 parts of radix sileris and 8-12 parts of papaya. The traditional Chinese medicine composition has the advantages that various Chinese herbal medicine materials of the traditional Chinese medicine composition are reasonably combined, medicine effect can be brought into full play, and the traditional Chinese medicine composition is low in cost and free of side effect and has effects of tonifying the spleen and kidney, strengthening tendons and bones, benefiting essence and filling marrow, replenishing and activating blood, and the like; the traditional Chinese medicine composition is mainly used for treating the osteomyelitis with symptoms such as swelling and pain, suppuration and pressing pain; clinical medicine effect experiments show that the osteomyelitis cure rate of the traditional Chinese medicine composition reaches up to 67%, and the total effective rate of the traditional Chinese medicine composition is close to 100%.
Description
Technical field
The present invention relates to Chinese medicine composition, specifically one treats myelitic Chinese medicine composition.
Background technology
Osteomyelitis refers to that suppurative bacterium infects bone marrow, cortical bone and periosteum and the diseases associated with inflammation that causes, is mostly caused by haematogenous, is also manyly caused by wound or postoperative infection, how enters blood by the suppuration bacterium of furuncle carbuncle or other focuses and reaches osseous tissue.Bones of limbs two ends are subject to invade most, are the most common especially with hip joint.Common clinically have recurrent exerbation, has a strong impact on physical and mental health and work capacity.High heat, local pain during acute osteomyelitis onset, have diabrosis, suppurate, have sequestrum or cavity to be formed when transferring chronic osteomyelitis to.The normal threat to life of patient with severe symptoms, sometimes has to take the emergency approach of amputation, causes patient's lifelong disability.
The current common method for the treatment of of osteomyelitis mainly contains that focus is thoroughly removed, open spongy bone bone grafting and the Therapeutic Method that repeatedly rinses.These methods all need to perform the operation to patient, and therapeutic process is very painful, and costly.
Summary of the invention
Technical problem to be solved by this invention be to provide a kind of cost low, have no side effect, the myelitic Chinese medicine composition for the treatment of evident in efficacy.
In order to solve the problems of the technologies described above, the present invention adopts following technical scheme: one treats myelitic Chinese medicine composition, by weight, following raw material is comprised: Radix Rehmanniae Preparata 13-17, Radix Angelicae Sinensis 10-14, Fructus Psoraleae 9-11, the Radix Astragali 13-17, Poria 14-16, Rhizoma Drynariae 11-13, Radix Pseudostellariae 14-16, Rhizoma Chuanxiong 13-17, Radix Clematidis 9-11, Radix Achyranthis Bidentatae 10-14, Radix Saposhnikoviae 8-12, Fructus Chaenomelis 8-12.
Preferably, the weight portion of each raw material is: Radix Rehmanniae Preparata 15, Radix Angelicae Sinensis 12, Fructus Psoraleae 10, the Radix Astragali 15, Poria 15, Rhizoma Drynariae 12, Radix Pseudostellariae 15, Rhizoma Chuanxiong 15, Radix Clematidis 10, Radix Achyranthis Bidentatae 12, Radix Saposhnikoviae 10, Fructus Chaenomelis 10.
Preferably, the weight portion of each raw material is: Radix Rehmanniae Preparata 13, Radix Angelicae Sinensis 10, Fructus Psoraleae 9, the Radix Astragali 13, Poria 14, Rhizoma Drynariae 11, Radix Pseudostellariae 14, Rhizoma Chuanxiong 13, Radix Clematidis 9, Radix Achyranthis Bidentatae 10, Radix Saposhnikoviae 8, Fructus Chaenomelis 8.
Preferably, the weight portion of each raw material is: Radix Rehmanniae Preparata 17, Radix Angelicae Sinensis 14, Fructus Psoraleae 11, the Radix Astragali 17, Poria 16, Rhizoma Drynariae 13, Radix Pseudostellariae 16, Rhizoma Chuanxiong 17, Radix Clematidis 11, Radix Achyranthis Bidentatae 14, Radix Saposhnikoviae 12, Fructus Chaenomelis 12.
The present invention treats myelitic Chinese medicine composition and can decoct into decoction by Chinese medicine method and take.
The present invention also provides a kind of pharmaceutical preparation, comprises the myelitic Chinese medicine composition of described treatment and pharmaceutically acceptable carrier or excipient.For the present invention, first the myelitic Chinese medicine composition for the treatment of to be carried out the extraction of active component through this area conventional extraction techniques sedimentation as pure in water extraction or the alcohol extracting-water precipitating method of falling, then active component is combined with pharmaceutically acceptable carrier or excipient, pharmaceutically acceptable carrier or excipient are selected according to different dosage forms, and these carriers used or excipient can determine for the those of ordinary skill of pharmaceutical field.Making pharmaceutical preparation can facilitate patient to take.
Preferably, described pharmaceutical preparation is granule, tablet or pill.
Radix Rehmanniae Preparata in the present invention, has another name called Radix Rehmanniae Preparata or throws oneself on the ground, and belongs to goatweed, is a kind of first-class Chinese crude drug, has YIN nourishing of enriching blood, effect that beneficial essence fills out marrow.Can be used for the diseases such as blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, metrorrhagia, diseases such as also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, pass out semen, quench one's thirst.
Radix Angelicae Sinensis, sweet in the mouth, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, effect of menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be usually used in the diseases such as blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.
Fructus Psoraleae, has another name called Fructus Psoraleae, bitter, pungent, warm.Return kidney, spleen channel.There is kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, lumbago due to renal deficiency, frequent micturition, bed-wetting, kidney leak, effect of warming spleen and stopping diarrha, helping inspiration to relieve asthma.For diseases such as the Diarrhoeas that impotence due to deficiency of the kidney, soreness of the waist and knees cold type of pain, emission due to deficiency of the kidney, the enuresis, frequent micturition, deficiency of spleen-YANG and kidneyYANG cause.
The Radix Astragali, the sweet temperature of property, returns lung meridian, has tonifying Qi and lifting yang, a function that benefit defends consolidating superficial resistance.For the disease such as exterior deficiency spontaneous perspiration, night sweat due to yin deficiency, acute nephritis edema, yang-energy weakness, skin infection diabrosis, syndrome of deficiency of lung qi, the deficiency of vital energy be weak, modern medicine study shows, the Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Poria, sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.There is effect of promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.Have loose bowels for edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool, irritability, the disease such as palpitation with fear insomnia.
Rhizoma Drynariae, another name precipice Rhizoma Zingiberis Recens, rock connect Rhizoma Zingiberis Recens.Bitter in the mouth, warm in nature.The effect of there is the kidney invigorating, invigorate blood circulation, stopping blooding.Cure mainly the disease such as chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus of suffering from a deficiency of the kidney.
Radix Pseudostellariae, sweet in the mouth, micro-hardship, property is put down.Return spleen, lung meridian.There is effect of replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.The diseases such as, inappetence, after being ill weakness tired for insufficiency of the spleen body, deficiency of both vital energy and Yin, spontaneous perspiration are thirsty, dryness of the lung dry cough.
Rhizoma Chuanxiong, acrid in the mouth, temperature.Enter liver, gallbladder meridian.There is activating QI to alleviate the depression, method wind-dryness wet, effect of promoting blood circulation and stopping pain.Treat air-cooled headache and revolve the disease such as dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For the disease such as menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia.
Radix Clematidis is acrid in the mouth, salty, warm in nature.Return urinary bladder channel, Liver Channel.There is effect of wind-damp dispelling, the meridian dredging, the bone stalk that disappears.Cure mainly the diseases such as gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, knee joint cold type of pain, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, the pharynx of all a fishbone or other bone caught in the throat.
Radix Achyranthis Bidentatae, bitter in the mouth, sweet, sour, property is put down.Return liver, kidney channel.There is effect of eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards.Cure mainly that amenorrhea, dysmenorrhea, soreness of waist and knee joint, muscles and bones are unable, stranguria, edema, headache, dizzy, toothache, day skin ulcer, haematemesis, the disease such as epistaxis.
Radix Saposhnikoviae, acrid in the mouth, sweet, slightly warm in nature.There is effect of expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.For diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus just, effect of insufficiency of the spleen leading to overabundance of dampness.
Fructus Chaenomelis, sour in the mouth, warm in nature.Return liver, spleen channel.There is effect of relaxing muscles and tendons and activating QI and blood in the collateral stomach function regulating removing dampness.Be used for the treatment of arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, heat-damp in summer are vomited and diarrhoea, are had a cramp the disease such as spasm and pain, beriberi edema.
The advantage that the present invention treats myelitic Chinese medicine composition is:
The present invention uses Chinese medicine medicines compatibility, and cost is low, and formula is reasonable, and drug effect plays good, has no side effect, and has reinforcing spleen and kidney, strengthening the tendons and bones, and beneficial essence fills out marrow, effect such as to invigorate blood circulation of enriching blood.Cure mainly osteomyelitis.Disease opinion swells and ache, diabrosis, suppurates, the diseases such as tenderness.Verify through the clinical test of pesticide effectiveness, the present invention is to myelitic cure rate up to 67%, and total effective rate is close to 100%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
The various raw materials that following examples use, as being not specifically noted, are commercially available prod well known in the art.
Embodiment 1
One treats myelitic Chinese medicine composition, by weight, following raw material is comprised: Radix Rehmanniae Preparata 15g, Radix Angelicae Sinensis 12g, Fructus Psoraleae 10g, Radix Astragali 15g, Poria 15g, Rhizoma Drynariae 12g, Radix Pseudostellariae 15g, Rhizoma Chuanxiong 15g, Radix Clematidis 10g, Radix Achyranthis Bidentatae 12g, Radix Saposhnikoviae 10g, Fructus Chaenomelis 10g.
Embodiment 2
One treats myelitic Chinese medicine composition, by weight, following raw material is comprised: Radix Rehmanniae Preparata 13g, Radix Angelicae Sinensis 10g, Fructus Psoraleae 9g, Radix Astragali 13g, Poria 14g, Rhizoma Drynariae 11g, Radix Pseudostellariae 14g, Rhizoma Chuanxiong 13g, Radix Clematidis 9g, Radix Achyranthis Bidentatae 10g, Radix Saposhnikoviae 8g, Fructus Chaenomelis 8g.
Embodiment 3
One treats myelitic Chinese medicine composition, by weight, following raw material is comprised: Radix Rehmanniae Preparata 17g, Radix Angelicae Sinensis 14g, Fructus Psoraleae 11g, Radix Astragali 17g, Poria 16g, Rhizoma Drynariae 13g, Radix Pseudostellariae 16g, Rhizoma Chuanxiong 17g, Radix Clematidis 11g, Radix Achyranthis Bidentatae 14g, Radix Saposhnikoviae 12g, Fructus Chaenomelis 12g.
Embodiment 4
The clinical test of pesticide effectiveness
MethodsThe cases enrolled: through the patient being diagnosed as osteomyelitis, have osteomyelitis clinical symptoms one or more;
Usage and dosage is: the myelitic Chinese medicine composition of a secondary treatment is placed in pottery, add cold water to exceeding medical surfaces 4-5cm, soak half an hour, then after boiling with high heat, again with slow fire boiling 40min, the medicinal liquid decocted by head leaches down in bowl, add water in filtering residue again and exceed medicinal residues surface 3-4cm, then with slow fire boiling 30min, the medicinal liquid decocted two leaches, the medicinal liquid decocted with head merges, as potion, patient takes potion day, and night takes, within 6 days, be a course for the treatment of, the formula provided using embodiment 1 to embodiment 3 is as the dosage of 1 auxiliary medicine;
Curative effect situation criterion: 1. cure.Malaise symptoms disappears completely, and X-ray film display bone destruction is disappeared; 2. effective.Malaise symptoms alleviates or partial disappearance, X-ray film display bone destruction improving situation; 3. invalid.Malaise symptoms is unchanged, and X-ray film display bone destruction situation is front without significant change with treatment.
Table 1 is the clinical pharrnacokinetics report of 300 routine osteomyelitis (co)s.
Table 1
| Group | To take medicine number | Healing number | Efficiently individual quantity | Invalid number | Cure rate | Total effective rate |
| Embodiment 1 | 100 | 67 | 31 | 2 | 67％ | 98％ |
| Embodiment 2 | 100 | 63 | 34 | 3 | 63％ | 97％ |
| Embodiment 3 | 100 | 65 | 31 | 4 | 65％ | 96％ |
Model case is as follows:
Hole, man, 63 years old.Patient two leg joint swells and ache, and lower limb knee joint bottom is red and swollen, and broken skin ulcer is suppurated, and tenderness sense is strong, and long-term disunion is osteomyelitis after diagnosing.Take the present invention and treat myelitic Chinese medicine composition, after 2 courses for the treatment of, swell and ache and alleviate to some extent, phenomenon of suppurating alleviates, and continues to take, and after 8 courses for the treatment of, recovery from illness, has no any side effect, follows up a case by regular visits to without recurrence after half a year.
Feng, female, 32 years old.Patient, because of unexpected traumatic injury, causes left elbow joint red and swollen, pain, does not prolongedly heal.By being diagnosed as subperiosteal abscess, Soft Tissue Abscess: An Experimental.Take the present invention and treat myelitic Chinese medicine composition, after 2 courses for the treatment of, red and swollen, pain alleviates, and continues to take, and after 5 courses for the treatment of, recovery from illness, has no any side effect, follows up a case by regular visits to without recurrence after half a year.
Seedling, man, 38 years old.Patient's spinal pain is myelitis after diagnosing.Take the present invention and treat myelitic Chinese medicine composition, after 2 courses for the treatment of, pain is alleviated to some extent, continues to take, and after 10 courses for the treatment of, recovery from illness, has no any side effect, follows up a case by regular visits to without recurrence after half a year.
In certain, female, 25 years old.The left leg joint of patient swells and ache, and with red and swollen, burning pain, walking disorder is osteomyelitis after diagnosing.Take the present invention and treat myelitic Chinese medicine composition, after 2 courses for the treatment of, swell and ache and alleviate to some extent, continue to take, after 5 courses for the treatment of, recovery from illness, has no any side effect, follows up a case by regular visits to without recurrence after half a year.
Shut out certain, man, 45 years old.Patient's hip joint swells and ache, and there is diabrosis in time, suppurates, and is osteomyelitis after diagnosing.Take the present invention and treat myelitic Chinese medicine composition, after 2 courses for the treatment of, pain is alleviated to some extent, and diabrosis alleviates, and continues to take, and after 10 courses for the treatment of, recovery from illness, has no any side effect, follows up a case by regular visits to without recurrence after half a year.
Be to be understood that example as herein described and embodiment only in order to illustrate, those skilled in the art can make various amendment or change according to it, when not departing from spirit of the present invention, all belong to protection scope of the present invention.
Claims (6)
1. the myelitic Chinese medicine composition for the treatment of, by weight, following raw material is comprised: Radix Rehmanniae Preparata 13-17, Radix Angelicae Sinensis 10-14, Fructus Psoraleae 9-11, the Radix Astragali 13-17, Poria 14-16, Rhizoma Drynariae 11-13, Radix Pseudostellariae 14-16, Rhizoma Chuanxiong 13-17, Radix Clematidis 9-11, Radix Achyranthis Bidentatae 10-14, Radix Saposhnikoviae 8-12, Fructus Chaenomelis 8-12.
2. treat a myelitic Chinese medicine composition, by weight, comprise following raw material: Radix Rehmanniae Preparata 15, Radix Angelicae Sinensis 12, Fructus Psoraleae 10, the Radix Astragali 15, Poria 15, Rhizoma Drynariae 12, Radix Pseudostellariae 15, Rhizoma Chuanxiong 15, Radix Clematidis 10, Radix Achyranthis Bidentatae 12, Radix Saposhnikoviae 10, Fructus Chaenomelis 10.
3. treat a myelitic Chinese medicine composition, by weight, comprise following raw material: Radix Rehmanniae Preparata 13, Radix Angelicae Sinensis 10, Fructus Psoraleae 9, the Radix Astragali 13, Poria 14, Rhizoma Drynariae 11, Radix Pseudostellariae 14, Rhizoma Chuanxiong 13, Radix Clematidis 9, Radix Achyranthis Bidentatae 10, Radix Saposhnikoviae 8, Fructus Chaenomelis 8.
4. treat a myelitic Chinese medicine composition, by weight, comprise following raw material: Radix Rehmanniae Preparata 17, Radix Angelicae Sinensis 14, Fructus Psoraleae 11, the Radix Astragali 17, Poria 16, Rhizoma Drynariae 13, Radix Pseudostellariae 16, Rhizoma Chuanxiong 17, Radix Clematidis 11, Radix Achyranthis Bidentatae 14, Radix Saposhnikoviae 12, Fructus Chaenomelis 12.
5. a pharmaceutical preparation, comprises the myelitic Chinese medicine composition for the treatment of according to claim 1 and pharmaceutically acceptable carrier or excipient.
6. pharmaceutical preparation as claimed in claim 5, is characterized in that: described pharmaceutical preparation is granule, tablet or pill.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108815424A (en) * | 2018-08-21 | 2018-11-16 | 王兴义 | A kind of Chinese medicine composition and preparation method thereof for treating bacterium infection |
| CN110833582A (en) * | 2019-07-09 | 2020-02-25 | 禹兆军 | Processing technique and therapy of osteitis decoction |
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| CN1241421A (en) * | 1998-07-02 | 2000-01-19 | 袁方 | Medicine for treating marrow disease |
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2015
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1241421A (en) * | 1998-07-02 | 2000-01-19 | 袁方 | Medicine for treating marrow disease |
Non-Patent Citations (2)
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| 孙世发: "《中华医方.外科篇.下及骨伤科篇》", 31 March 2015, 科学技术文献出版社 * |
| 费兰波等: "《现代名中医骨科绝技》", 31 May 2002, 科学技术文献出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108815424A (en) * | 2018-08-21 | 2018-11-16 | 王兴义 | A kind of Chinese medicine composition and preparation method thereof for treating bacterium infection |
| CN110833582A (en) * | 2019-07-09 | 2020-02-25 | 禹兆军 | Processing technique and therapy of osteitis decoction |
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