CN103585483A - Traditional Chinese medicine composition for treating knee osteoarthritis and preparation method of same - Google Patents

Abstract

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine composition for treating knee osteoarthritis and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following bulk drugs in parts by weight: 5-50 parts of radix clematidis, 10-15 parts of drynaria rhizome, 10-20 parts of lycopodiumclavatum, 5-15 parts of radix angelicaepubescentis, 5-10 parts of stephaniatetrandra, 3-9 parts of monkshood, 1-15 parts of long-noded pit viper, 5-10 parts of zaocysdhumnade, 10-15 parts of pawpaw, 10-15 parts of eucommiaulmoides, 10-30 parts of caulis spatholobi, 3-10 parts of gastrodiaelata, 5-15 parts of earthworm, 2-5 parts of scorpion, and 3-10 parts of ligusticumwallichii. The composition provided by the invention has the effects of expelling wind-damp, strengthening muscles and bones,warming channels, expelling cold, dredging collaterals, tonifying the spleen and the kidney, being good for essence and blood, promoting blood circulation to remove blood stasis, and relieving pain; the knee pain can be effectivelyeliminated, and the absorption of a spurproliferated on an intercondyloid spine is promoted, so that the spur becomes blunt after a long period of time, and the effects are remarkable.

Description

A kind of arthropathic Chinese medicine composition of kneecap and preparation method thereof for the treatment of

Technical field

The invention belongs to technical field of Chinese medicines, particularly a kind of arthropathic Chinese medicine composition of kneecap and preparation method thereof for the treatment of.

Background technology

Knee joint osseous arthritis belongs to motherland's medical science " numbness is sick " category.The name of disease of numbness sees in < < the earliest through > >, as < < Plain Questions numbness opinion > > points out: " so-called numbness person; each is with at that time, reinfection in the wet gas of wind and cold also." its pathogenesis is: the heresy invasion and attack that wind and cold is damp and hot or strain, with numbness resistance meridians, make qi-blood-body fluid operation not smooth, and stasis is the stasis of blood, and stop as expectorant in Tianjin, and expectorant stasis of blood knot and exopathogen are harmonious, and go deep into bone joint.Clinical in the gonalgia, joint stuffiness, especially upstairs, sit with the pain while standing of squatting down and increase the weight of, it is primary symptom that arthroncus, strong, distortion, touching difficulty heal etc.With the passing of time numbness disease, also can cause internal organs pathological changes by the internal organs of meridians biography, wherein more common with the obstruction of heart-QI.

Knee joint osseous arthritis is the common chronic degenerative joint disease of middle-aged and elderly people, and it affects muscle, synovial membrane, ligament, subchondral bone matter then by the impaired onset of articular cartilage, causes joint deformity and afunction.Use merely not only weak curative effect of western medicine primary disease, and complication is many.As used nonsteroidal anti-inflammatory analgetic, easy damaged gastrointestinal tract, the drawbacks such as the easy recurrence of operative treatment, patient can't bear speech bitterly.

Summary of the invention

For overcoming the deficiencies in the prior art part, the object of the present invention is to provide a kind of arthropathic Chinese medicine composition of kneecap and preparation method thereof for the treatment of.Said composition has: wind-damp dispelling, bone and muscle strengthening, dispelling cold by warming the meridian dredging collateral, the merit of spleen reinforcing kidney, benefiting essence-blood, promoting blood circulation, removing blood stasis and relieving pain; Can efficient solution except the gonalgia, promote the bony spur of intercondyloid spine hypertrophy to absorb, the of a specified duration bony spur rust that makes, effect is remarkable.

For achieving the above object, the technical scheme that the present invention takes is as follows:

The arthropathic Chinese medicine composition of kneecap, is made by each crude drug of following portions by weight: Radix Clematidis 5-50 part, Rhizoma Drynariae 10-15 part, Herba Lycopodii 10-20 part, Radix Angelicae Pubescentis 5-15 part, Radix Stephaniae Tetrandrae 5-10 part, Radix Aconiti 3-9 part, Agkistrodon 1-15 part, Zaocys 5-10 part, Fructus Chaenomelis 10-15 part, Cortex Eucommiae 10-15 part, Caulis Spatholobi 10-30 part, Rhizoma Gastrodiae 3-10 part, Pheretima 5-15 part, Scorpio 2-5 part, Rhizoma Chuanxiong 3-10 part.

Further, the parts by weight of described each crude drug are preferably: 15 parts of Radix Clematidis, 10 parts of Rhizoma Drynariae, 15 parts of Herba Lycopodiis, 10 parts of Radix Angelicae Pubescentiss, 10 parts of Radixs Stephaniae Tetrandrae, 6 parts of Radix Aconitis, 10 parts of Agkistrodons, 7 parts of Zaocyss, 15 parts of Fructus Chaenomeliss, 10 parts of the Cortexs Eucommiae, 20 parts of Caulis Spatholobis, 10 parts, Rhizoma Gastrodiae, 10 parts of Pheretimas, 3 parts of Scorpios, 10 parts of Rhizoma Chuanxiongs.

Described Chinese medicine composition is made any acceptable preparation clinically according to a conventional method, such as decoct, pill or capsule.Can, according to the needs of different preparations, choose and add corresponding conventional adjuvant.

Preparation method and using method:

Pain phase decoct: in weight/volume, take Radix Clematidis 5-50g, Rhizoma Drynariae 10-15g, Herba Lycopodii 10-20g, Radix Angelicae Pubescentis 5-15g, Radix Stephaniae Tetrandrae 5-10g, Radix Aconiti 3-9g, Agkistrodon 1-15g, Zaocys 5-10g, Fructus Chaenomelis 10-15g, Cortex Eucommiae 10-15g, Caulis Spatholobi 10-30g, Rhizoma Gastrodiae 3-10g, Pheretima 5-15g, Scorpio 2-5g, Rhizoma Chuanxiong 3-10g, then this 15 taste Chinese medicine is put into marmite, first decocts and adds water 600ml, soak 30min, after first boiling with high heat, use again 30min at a simmer, the about 350ml of taking liquid; Second decocts and adds water 500ml, after first boiling with high heat, uses 25min at a simmer, the about 350ml of taking liquid again; After decocting liquid medicine mixing two, take at twice, service once decoction being taken warmly sooner or later.

The pain relief phase is with honeyed pill, concentrated pill or capsule: take by weight ratio 15 parts of Radix Clematidis, 10 parts of Rhizoma Drynariae, 15 parts of Herba Lycopodiis, 10 parts of Radix Angelicae Pubescentiss, 10 parts of Radixs Stephaniae Tetrandrae, 6 parts of Radix Aconitis, 10 parts of Agkistrodons, 7 parts of Zaocyss, 15 parts of Fructus Chaenomeliss, 10 parts of the Cortexs Eucommiae, 20 parts of Caulis Spatholobis, 10 parts, Rhizoma Gastrodiae, 10 parts of Pheretimas, 3 parts of Scorpios, 10 parts of Rhizoma Chuanxiongs, then after this 15 taste Chinese medicine being pulverized, cross 100 orders or 120 mesh sieves, make after superfine medicated powder: 1. medicated powder and honey are made to honeyed pill by 1:1.5 part by weight, every ball 3g, each serving 6g, take every day twice; Or 2. packing medicated powder into Capsules, every 0.3g, each serving 6, takes three times every day; Or 3. medicated powder is made to concentrated pill by prior art processes, every 8 balls are equivalent to crude drug in whole 3g, each serving 8 balls, take every day three times.

Pharmacology of the present invention is as follows:

Radix Clematidis: acrid in the mouth, salty.Warm in nature.Return urinary bladder channel.There is wind-damp dispelling, the meridian dredging, the merit of a fishbone or other bone caught in the throat that disappears.The pungent loose temperature of this product is logical, and property is apt to away suddenly, and the current twelve regular channels can wind-damp dispelling, and stopping numbness pain can stimulate the menstrual flow again.All rheumatic arthralgia, apathy, no matter all available up and down, be rheumatic arthralgia key medicine.This product salty in the mouth, has the softening the hard mass a fishbone or other bone caught in the throat effect that disappears.Modern pharmacological research proves: " this product has analgesic activity, and its vinegar liquid has certain emollescence to fish bony spur, and makes part of flaccid muscles, impels bony spur to come off, and its decoct has obvious antibacterial action etc.”

Rhizoma Drynariae: bitter in the mouth.Warm in nature.Return liver, kidney channel.The merit with invigorate blood circulation continuous wound, the kidney invigorating bone strengthening.The sweet temperature of this product enters Liver and kidney warp, has warming and recuperating the kidney-YANG, bone and muscle strengthening, benefit deficient, again can promoting the circulation of blood arteries and veins, reuniting the fractured tendons and bones, the pain relieving of curing the wound.The diseases such as the damage for the treatment of tumbling down, lumbago due to renal deficiency flaccidity of the lower limbs.Modern pharmacological research proves: this product contains davallic acid, can promote the absorption of bone to calcium, and improves blood calcium and serium inorganic phosphorus level, is conducive to the healing of fracture; The chondrocyte function that also has some improvement, postpones the effect of cell degeneration and obvious analgesic activity etc.

Herba Lycopodii: bitter in the mouth, pungent.Warm in nature.Return Liver Channel.The merit with wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, treatment rheumatic arthralgia, extremities joint are ached, activities adverse, munbness etc.

Radix Angelicae Pubescentis: acrid in the mouth, hardship.Slightly warm in nature.Return liver, urinary bladder channel.The merit of there is wind-damp dispelling, stopping numbness pain, inducing sweat.This product energy wind-damp dispelling, expelling cold and freeing bi, all anemofrigid-damp arthralgia are all available.Kind descending because of it, especially with waist knee joint, lower limb joints of foot pain subordinate portion cold-damp severe one, be advisable.Modern pharmacological research proves: this product has the effects such as arthritis, analgesia the direct blood vessel dilating of energy.

Radix Stephaniae Tetrandrae: bitter in the mouth, pungent.Cold in nature.Return bladder, kidney, spleen channel.The merit with wind-damp dispelling, pain relieving, inducing diuresis to remove edema.This product is pungent can a surname fall apart, and bitter cold is fallen and let out, and energy wind-damp dispelling, heat clearing away removing obstruction in the collateral to relieve pain, be suitable for damp and hot inclined to one side victor especially, and disease sees that joint is tired of pain, joint stuffiness etc.

Radix Aconiti: acrid in the mouth, hardship.Warm in nature.GUIXIN, spleen, liver, kidney channel.The merit with expelling wind and removing dampness, dispersing cold for relieving pain.This product has stronger dispersing cold for relieving pain effect, controls headache due to cold-damp, general pain, severe and migratory arthralgia pain, unable to flex and stretch the extremities person.Modern pharmacological research proves: this product has the effects such as analgesia, calmness, local anesthesia, and zoopery arthritis is had to consumption.

Agkistrodon: sweet in the mouth, salty.Warm in nature.Return Liver Channel.The merit with dispelling wind and removing obstruction in the collateral, arresting convulsion relieving convulsion.This product power of dispeling the wind is violent, and kind the meridian dredging again, therefore for diseases such as rheumatoid arthritis stubborn, numb limbs and tense tendons, the contractures of muscle arteries and veins.

Zaocys: sweet in the mouth.Property is put down.Return Liver Channel.The merit with dispelling wind and removing obstruction in the collateral, arresting convulsion relieving convulsion.This product can be searched ailment said due to cold or exposure, saturating joint, and dispelling the wind and dampness pathogens insensitive impediment, brothers are slow can not stretch the diseases such as act.

Fructus Chaenomelis: sour in the mouth.Warm in nature.Return liver, spleen channel.The merit with relaxing muscles and tendons and activating QI and blood in the collateral, dehumidifying stomach function regulating.This product has good relaxing muscles and tendons and activating QI and blood in the collateral effect, and energy damp eliminating eliminating impediment, is the diseases such as the key medicine of lingering pathogenic wind insensitive impediment, spasm of muscles and vessels, dispelling the wind and dampness pathogens arthralgia pain, the contracture of muscle arteries and veins.Modern pharmacology experimental results show that: this product has obvious detumescence effect to zoopery arthritis.

The Cortex Eucommiae: sweet in the mouth.Warm in nature.Return liver, kidney channel.There is the functions such as invigorating the liver and kidney, bone and muscle strengthening.Therefore the soreness of waist and knee joint for the treatment of liver, kidney deficiency, the lower limb soft disease of waiting of withering.< < book on Chinese herbal medicine converges says > >: " void of all parts of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, the non-Cortex Eucommiae is not mended; The part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is wet, and the non-Cortex Eucommiae is unfavorable; The acid of foot shin, the non-Cortex Eucommiae is not gone; Waist knee joint is pain, and the non-Cortex Eucommiae is not removed.”

Caulis Spatholobi: bitter in the mouth, sweet.Warm in nature.Return Liver Channel.Have that promoting the circulation of blood is enriched blood, the merit of regulating menstruation, relaxing muscles and tendons and activating QI and blood in the collateral.The nourshing blood and promoting blood circulation of this product energy and relaxing muscles and tendons and activating QI and blood in the collateral, the diseases such as dispelling the wind and dampness pathogens arthralgia pain, arthralgia, numb limbs and tense tendons.

Rhizoma Gastrodiae: sweet in the mouth.Property is put down.Return Liver Channel.The merit with relieving spasm by subduing liver-wind, suppressing liver-YANG, dispelling wind and removing obstruction in the collateral.This product can dispel exogenous wind, the meridian dredging, the diseases such as treatment wind apoplex involving the channels and collaterals, hands and feet caused by paralysis, numb limbs and tense tendons, spasm tic, again can dispelling the wind and dampness pathogens arthralgia pain, joint joint stuffiness person.

Pheretima: salty in the mouth.Cold in nature.Return liver, spleen, urinary bladder channel.There is the functions such as clearing heat for calming endogenous wind, dredging collateral.This product is longer than current meridians, heat clearing away cold in nature, can treat the pyretic arthralgia of joint congestion and swelling pain, joint stuffiness, treats again the diseases such as anemofrigid-damp arthralgia of limbs joint numb pain, joint stuffiness.

Scorpio: acrid in the mouth.Property is put down.Return Liver Channel.The merit with endogenous wind stopping relieving convulsion, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.This product had both been calmed down liver-wind, expel wind to dredge collateral pain relieving again, and to anemofrigid-damp arthralgia obstinate, the contracture of muscle arteries and veins, very the insensitive impediment effect of joint deformity is rather good.

Rhizoma Chuanxiong: acrid in the mouth.Warm in nature.Return liver, gallbladder, pericardium channel.The merit with blood-activating and qi-promoting, wind-expelling pain-stopping.The pungent loose temperature of this product is logical, can invigorate blood circulation, again can circulation of qi promoting, be " gas medicine in blood ", can " lower regulating menstruation water, middle relieving stagnation, the up head, bypass channels." expelling wind and activating blood circulation pain relieving, control limbs pain numbness, rheumatic Bi syndrome etc.

All medicine compatibilities above, the merit of playing altogether wind-damp dispelling, bone and muscle strengthening, dispelling cold by warming the meridian dredging collateral, spleen reinforcing kidney, benefiting essence-blood, promoting blood circulation, removing blood stasis and relieving pain; Be used for the treatment of the evil numbness resistance meridians that wind and cold is damp and hot, make qi-blood-body fluid operation not smooth, expectorant stasis of blood knot is also harmonious with exopathogen, go deep into the gonalgia due to bone joint, joint stuffiness, upstairs, sit with the pain while standing of squatting down and increase the weight of, arthroncus, strong, distortion, the touching difficulty disease such as heal.Chinese medicine composition of the present invention can promote bony spur to absorb, and clothes can make that bony spur is softening, rust for a long time, effective eliminate pain, and clinical efficacy is remarkable.

The specific embodiment

Below in conjunction with specific embodiment, technical solution of the present invention is done to introduce in detail further, but protection scope of the present invention is not limited to this:

Embodiment 1

Radix Clematidis 5g, Rhizoma Drynariae 12g, Herba Lycopodii 10g, Radix Angelicae Pubescentis 15g, Radix Stephaniae Tetrandrae 7g, Radix Aconiti 9g, Agkistrodon 3g, Zaocys 5g, Fructus Chaenomelis 10g, Cortex Eucommiae 12g, Caulis Spatholobi 30g, Rhizoma Gastrodiae 3g, Pheretima 15g, Scorpio 5g, Rhizoma Chuanxiong 3g.

Pain phase decoct: above-mentioned 15 taste Chinese medicines are put into marmite, and first decocts and add water 600ml, soaks 30min, uses 30min at a simmer, the about 350ml of taking liquid after first boiling with high heat again; Second decocts and adds water 500ml, after first boiling with high heat, uses 25min at a simmer, the about 350ml of taking liquid again; After decocting liquid medicine mixing two, take at twice, service once decoction being taken warmly sooner or later.

The pain relief phase is used honeyed pill, concentrated pill or capsule: after above-mentioned 15 taste Chinese medicines are pulverized, cross 100 orders or 120 mesh sieves, make after superfine medicated powder: 1. medicated powder is made to honeyed pill with sweet by 1:1.5 part by weight, every ball 3g, each serving 6g, takes twice every day; Or 2. packing medicated powder into Capsules, every 0.3g, each serving 6, takes three times every day; Or 3. medicated powder is made to concentrated pill by prior art processes, every 8 balls are equivalent to crude drug in whole 3g, each serving 8 balls, take every day three times.

Embodiment 2

Radix Clematidis 15g, Rhizoma Drynariae 10g, Herba Lycopodii 15g, Radix Angelicae Pubescentis 10g, Radix Stephaniae Tetrandrae 10g, Radix Aconiti 6g, Agkistrodon 10g, Zaocys 7g, Fructus Chaenomelis 15g, Cortex Eucommiae 10g, Caulis Spatholobi 20g, Rhizoma Gastrodiae 10g, Pheretima 10g, Scorpio 3g, Rhizoma Chuanxiong 10g.

Preparation method and using method are with embodiment 1.

Embodiment 3

Radix Clematidis 50g, Rhizoma Drynariae 15g, Herba Lycopodii 20g, Radix Angelicae Pubescentis 5g, Radix Stephaniae Tetrandrae 5g, Radix Aconiti 3g, Agkistrodon 15g, Zaocys 10g, Fructus Chaenomelis 5g, Cortex Eucommiae 15g, Caulis Spatholobi 10g, Rhizoma Gastrodiae 7g, Pheretima 5g, Scorpio 21g, Rhizoma Chuanxiong 7g.

Preparation method and using method are with embodiment 1.

clinical trial

1.1 physical data

From year August in January, 2000 to 2013, filter out 120 routine knee joint osseous arthritis patients.All cases is all made a definite diagnosis through multiple inspections such as health check-up and X ray or DR sheets, and without serious liver, kidney, core function badness.It is divided into treatment group 60 examples at random, male 27 examples wherein, female's 33 examples, age: 33-76 year, 60.5 years old mean age; Matched group 60 examples, male 29 examples wherein, female's 31 examples, age: 35-75 year, 60 years old mean age.Two groups at aspects such as sex, age, symptoms more all without significant difference (p ﹥ 0.05), there is comparability, refer to table 1.

Table 1 liang group case ordinary circumstance comparison

Note: two groups of comparisons: p ﹥ 0.05

1.2 diagnostic criteria

1. there is knee joint damaged, the damp and hot history of having a cold; 2. knee joint severe pain, joint stuffiness, enlargement, stiff, distortion; 3. body of the tongue purple is dim, tongue white, stringy and hesitant pulse; 4. knee joint X ray or DR or CT etc. affect to learn and check prompting intercondyloid spine hypertrophy.

1.3 Therapeutic Method

Matched group: adopt routine of western medicine treatment, Ibumetin Retavd or Sustained Release Tablet of Diclofenac Sodium for analgesia; Stiff joint stuffiness is at Injection in knuckle articular cavity hyaluronic acid sodium, shot 2ml, and 1 time weekly, continuous 5 weeks is a course for the treatment of.

Treatment group: with on routine of western medicine treatment basis, add the embodiment of the present invention 2 prescriptions and preparation method thereof, using method at matched group.

Treat respectively after 5 weeks for two groups, treat the forward and backward DR sheet inspection of all carrying out, observe intercondyloid spine hypertrophy or absorbing state and clinical symptoms and improve situation.

1.4 therapeutic evaluatioies:

1.4.1 effective: the gonalgia disappears, bend and stretch flexibly, upstairs or the pain while standing of squatting down disappear with arthroncus, knee joint DR sheet observation: intercondyloid spine hypertrophy place rust.

1.4.2 effective: the gonalgia is alleviated, bend and stretch more flexibly, upstairs or the pain relief while standing of squatting down, arthroncus disappears substantially, and knee joint DR sheet is observed: intercondyloid spine hypertrophy place is rust slightly.

1.4.3 invalid: clinical symptoms is not improved, knee joint DR sheet is observed: intercondyloid spine hypertrophy place is without rust.

1.5 statistical method

Data represent by rate, adopt x ²check, take p < 0.05 as difference, has statistical significance.

1.6 result

1.6.1 before and after treatment, two groups of symptoms are improved situation comparison

Treatment group is at matched group with adding Chinese medicine composition of the present invention on routine of western medicine treatment basis, and clinical symptoms improvement rate (86%) is obviously better than matched group merely by routine of western medicine treatment clinical symptoms improvement rate (48%), refers to table 2.

Before and after table 2 liang group treatment, clinical symptoms is improved number of cases and improvement rate

Note: improve=effective+effectively

1.6.2 untoward reaction

Matched group has 6 examples with occurring stomachache, acid regurgitation after analgesic.Treatment group is not found any untoward reaction.Anemia of pregnant woman's forbidding.

model case

Case 1

Yin so-and-so, man, 56 years old, peasant ，Xi Xishao township Wang Dongshao people from village, on July 19th, 2011, came inventor to locate to go to a doctor with " knee joint osseous arthritis ".Over 5 years, often there is double knee joint pain in patient, cold or tired rear pain increases the weight of whenever, heat or the rear pain relief of having a rest.In nearly February, double knee joint pain the People's Hospital, the ，Zeng Nanyue County Orthopaedics Clinic that exacerbates is treated, and effect is not good enough, therefore come inventor to locate to seek medical advice.Disease is seen: double knee joint severe pain, can not walk, and joint joint stuffiness, the pain while standing of often going upstairs or squat down increases the weight of, the light enlargement in joint, local color of the leather is not red, and that touches is not hot, and the pain increased for cold or tired patella whenever; Pale tongue, white and thin fur, deep-slow pulse and string; DR sheet prompting: double knee joint intercondyloid spine hypertrophy.

Dialectical analysis: the wet heresy that is affected by the cold, and the cold victory partially of sense, cold main spasm, its property stagnates, and the resistance of QI and blood numbness is obstructed, therefore see double knee joint severe pain.Lao Ze consumption is hindered knee joint QI and blood, therefore the pain increased after tired.Meet cold blood more puckery, pain increases very.Wind-cold damp pathogen is kept muscle, ，Ze joint, joint joint stuffiness.Cold being a kind of YIN pathogen, therefore joint silght enlargement, local color of the leather is not red, that touches is not hot.Pale tongue, white and thin fur, deep and hesitant pulse and string is resembling of domination of cold.

Tcm diagnosis: numbness sick (arthralgia aggravated by cold).

The rule for the treatment of: wind-damp dispelling, bone and muscle strengthening, dispelling cold by warming the meridian dredging collateral, spleen reinforcing kidney, benefiting essence-blood, promoting blood circulation, removing blood stasis and relieving pain.

Side's medicine: the embodiment of the present invention 2 prescriptions, preparation method and using method.

Western medicine diagnose: two knee joint osseous arthritis.

Western medicine: alleviating pain Ibumetin Retavd, in two knee joint cavities, inject respectively hyaluronic acid sodium, all the other give symptomatic treatment.

After treating 2 weeks, double knee joint pain obviously alleviates, and arthroncus disappears, the pain relief while standing of going upstairs or squat down.After advising and taking continuously 5 weeks, double knee joint pain disappears, and go upstairs or squat down while standing, or the long slightly sense of travel time is uncomfortable.Advising and continue to take honey pill agent half a year, take to symptomatology after March and disappear, there is not double knee joint pain after living in dry building yet, and clinical cure, by repeatedly following up a case by regular visits to, so far without recurring.

Case 2

Fan so-and-so, female, 66 years old, peasant ，Xi Sizhuan township bean people from village, on June 12nd, 2012, came inventor to locate to go to a doctor with " two knee joint osseous arthritis ".Patient is over 6 years, double knee joint pain, outbreak repeatedly, whenever rainy weather have a bath or fatigue after the many places treatment such as double knee joint the pain increased ，Zeng Dao Nanyue County the People's Hospital's Orthopaedics Clinic and Zhengzhou City Orthopedic Hospital, effect is not good enough, therefore come inventor to locate to seek medical advice.Disease is seen: double knee joint has an intense pain, swelling, and muscular soreness, two lower limb are weighing, and two foot pains are numb with big toe; Light red tongue, tongue is greasy in vain, relaxed and soft pulse; DR sheet prompting: two knee joint intercondyloid spine hypertrophy.

Dialectical analysis: the wet heresy that is affected by the cold, and sense damp wins partially, and cold-dampness numbness, QI and blood is obstructed, therefore double knee joint sharp ache and swelling.Because of damp pathogen being sticky and stagnant in nature, deep, the wet meridians of noting, the muscle of being detained, joint, QI-blood circulation is obstructed, and sees that double knee joint is swelling, aches, joint stuffiness.Skin channels is turbid damp retardance, and nutrient blood operation is not smooth, and sees two vola portions and big toe numbness.Overcast and rainy or wet Sheng of having a bath, therefore the pain increased.Fatigue is wasting QI-blood, therefore pain increases.Light red tongue, white and thin fur, relaxed and soft pulse are damp resembling of Sheng partially.

Tcm diagnosis: numbness sick (damp arthralgia).

The rule for the treatment of: wind-damp dispelling, bone and muscle strengthening, dispelling cold by warming the meridian dredging collateral, spleen reinforcing kidney, benefiting essence-blood, promoting blood circulation, removing blood stasis and relieving pain.

Side's medicine: the embodiment of the present invention 2 prescriptions, preparation method and using method.

Western medicine diagnose: two knee joint osseous arthritis.

Western medicine: alleviating pain Sustained Release Tablet of Diclofenac Sodium, in two knee joint cavities, inject respectively hyaluronic acid sodium, all the other give symptomatic treatment.

After treating 10 days, double knee joint pain obviously alleviates, and the swelling of knee joint portion disappears, and muscular soreness and two edeam of legs sense and alleviated, and two volas and big toe are numb.After advising continuous treatment 6 weeks, double knee joint pain disappears, and muscular soreness disappears, two lower limb heavy, two volas and numb basic disappearance of big toe, tongue, arteries and veins recover normally.Advising and continue to take honey pill agent half a year, take to symptomatology after February and disappear, there is not pain in normal activity double knee joint, and clinical cure, by repeatedly following up a case by regular visits to, so far without recurring.

Claims (6)

1. the arthropathic Chinese medicine composition for the treatment of kneecap, is characterized in that being made by each crude drug of following portions by weight: Radix Clematidis 5-50 part, Rhizoma Drynariae 10-15 part, Herba Lycopodii 10-20 part, Radix Angelicae Pubescentis 5-15 part, Radix Stephaniae Tetrandrae 5-10 part, Radix Aconiti 3-9 part, Agkistrodon 1-15 part, Zaocys 5-10 part, Fructus Chaenomelis 10-15 part, Cortex Eucommiae 10-15 part, Caulis Spatholobi 10-30 part, Rhizoma Gastrodiae 3-10 part, Pheretima 5-15 part, Scorpio 2-5 part, Rhizoma Chuanxiong 3-10 part.

2. the arthropathic Chinese medicine composition for the treatment of kneecap as claimed in claim 1, is characterized in that being made by each crude drug of following portions by weight: 15 parts of Radix Clematidis, 10 parts of Rhizoma Drynariae, 15 parts of Herba Lycopodiis, 10 parts of Radix Angelicae Pubescentiss, 10 parts of Radixs Stephaniae Tetrandrae, 6 parts of Radix Aconitis, 10 parts of Agkistrodons, 7 parts of Zaocyss, 15 parts of Fructus Chaenomeliss, 10 parts of the Cortexs Eucommiae, 20 parts of Caulis Spatholobis, 10 parts, Rhizoma Gastrodiae, 10 parts of Pheretimas, 3 parts of Scorpios, 10 parts of Rhizoma Chuanxiongs.

3. the arthropathic Chinese medicine composition for the treatment of kneecap as claimed in claim 1 or 2, is characterized in that: make according to a conventional method any acceptable preparation clinically.

4. the arthropathic Chinese medicine composition for the treatment of kneecap as claimed in claim 3, is characterized in that: described preparation is decoct, honeyed pill, concentrated pill or capsule.

5. a preparation method for the treatment of the arthropathic Chinese medicine composition of kneecap, it is characterized in that: in weight/volume, take Radix Clematidis 5-50g, Rhizoma Drynariae 10-15g, Herba Lycopodii 10-20g, Radix Angelicae Pubescentis 5-15g, Radix Stephaniae Tetrandrae 5-10g, Radix Aconiti 3-9g, Agkistrodon 1-15g, Zaocys 5-10g, Fructus Chaenomelis 10-15g, Cortex Eucommiae 10-15g, Caulis Spatholobi 10-30g, Rhizoma Gastrodiae 3-10g, Pheretima 5-15g, Scorpio 2-5g, Rhizoma Chuanxiong 3-10g, then this 15 taste Chinese medicine is put into marmite, first decocts and adds water 600ml, soak 30min, after first boiling with high heat, use again 30min at a simmer, the about 350ml of taking liquid, second decocts and adds water 500ml, after first boiling with high heat, uses 25min at a simmer, the about 350ml of taking liquid again, after decocting liquid medicine mixing two, make decoct.

6. a preparation method for the treatment of the arthropathic Chinese medicine composition of kneecap, it is characterized in that: take by weight ratio 15 parts of Radix Clematidis, 10 parts of Rhizoma Drynariae, 15 parts of Herba Lycopodiis, 10 parts of Radix Angelicae Pubescentiss, 10 parts of Radixs Stephaniae Tetrandrae, 6 parts of Radix Aconitis, 10 parts of Agkistrodons, 7 parts of Zaocyss, 15 parts of Fructus Chaenomeliss, 10 parts of the Cortexs Eucommiae, 20 parts of Caulis Spatholobis, 10 parts, Rhizoma Gastrodiae, 10 parts of Pheretimas, 3 parts of Scorpios, 10 parts of Rhizoma Chuanxiongs, then after this 15 taste Chinese medicine being pulverized, cross 100 orders or 120 mesh sieves, make after superfine medicated powder: 1. medicated powder and honey are made to honeyed pill by 1:1.5 part by weight, every ball 3g; Or 2. pack medicated powder into Capsules and make capsule, every 0.3g; Or 3. medicated powder is made to concentrated pill by prior art processes, every 8 balls are equivalent to crude drug in whole 3g.