CN103585483B - Traditional Chinese medicine composition for treating knee osteoarthritis and preparation method of same - Google Patents
Traditional Chinese medicine composition for treating knee osteoarthritis and preparation method of same Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine composition for treating knee osteoarthritis and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following bulk drugs in parts by weight: 5-50 parts of radix clematidis, 10-15 parts of drynaria rhizome, 10-20 parts of lycopodiumclavatum, 5-15 parts of radix angelicaepubescentis, 5-10 parts of stephaniatetrandra, 3-9 parts of monkshood, 1-15 parts of long-noded pit viper, 5-10 parts of zaocysdhumnade, 10-15 parts of pawpaw, 10-15 parts of eucommiaulmoides, 10-30 parts of caulis spatholobi, 3-10 parts of gastrodiaelata, 5-15 parts of earthworm, 2-5 parts of scorpion, and 3-10 parts of ligusticumwallichii. The composition provided by the invention has the effects of expelling wind-damp, strengthening muscles and bones,warming channels, expelling cold, dredging collaterals, tonifying the spleen and the kidney, being good for essence and blood, promoting blood circulation to remove blood stasis, and relieving pain; the knee pain can be effectivelyeliminated, and the absorption of a spurproliferated on an intercondyloid spine is promoted, so that the spur becomes blunt after a long period of time, and the effects are remarkable.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly one treats arthropathic Chinese medicine composition of kneecap and preparation method thereof.
Background technology
Knee joint osseous arthritis belongs to motherland's medical science " numbness is sick " category.The name of disease of numbness sees "Nei Jing" the earliest, as " Plain Questions numbness opinion " is pointed out: " so-called numbness person, respectively with at that time, reinfection in the wet gas of wind and cold also." its pathogenesis is: the heresy invasion and attack that wind and cold is damp and hot or strain are with numbness resistance meridians, and qi-blood-body fluid is run smooth, stasis is the stasis of blood, and Tianjin is stopped as expectorant, and expectorant stasis of blood knot and exopathogen are harmonious, and gos deep into bone joint.Clinical in the gonalgia, joint stuffiness, especially upstairs, sit with squat down stand time pain increase the weight of, arthroncus, strong, distortion, touching difficulty to heal etc. as primary symptom.With the passing of time, the internal organs that also can be passed by meridians, cause internal organs pathological changes to numbness disease, wherein more common with the obstruction of heart-QI.
Knee joint osseous arthritis is the common chronic degenerative joint disease of middle-aged and elderly people, and it is then affected muscle, synovial membrane, ligament, subchondral bone matter by the impaired onset of articular cartilage, caused joint deformity and afunction.Simple western medicine primary disease not only weak curative effect, and complication is many.As with nonsteroidal anti-inflammatory analgetic, easy damaged gastrointestinal tract, operative treatment such as easily to recur at the drawback, and patient's pain can't bear speech.
Summary of the invention
For overcoming the deficiencies in the prior art part, one is the object of the present invention is to provide to treat arthropathic Chinese medicine composition of kneecap and preparation method thereof.Said composition has: wind-damp dispelling, bone and muscle strengthening, dispelling cold by warming the meridian dredging collateral, the merit of spleen reinforcing kidney, benefiting essence-blood, promoting blood circulation, removing blood stasis and relieving pain; Efficient solution can remove the gonalgia, promote that the bony spur of intercondyloid spine hypertrophy absorbs, of a specified duration makes bony spur rust, Be very effective.
For achieving the above object, the technical scheme taked of the present invention is as follows:
One treats the arthropathic Chinese medicine composition of kneecap, is made up of each crude drug of following portions by weight: Radix Clematidis 5-50 part, Rhizoma Drynariae 10-15 part, Herba Lycopodii 10-20 part, Radix Angelicae Pubescentis 5-15 part, Radix Stephaniae Tetrandrae 5-10 part, Radix Aconiti 3-9 part, Agkistrodon 1-15 part, Zaocys 5-10 part, Fructus Chaenomelis 10-15 part, Cortex Eucommiae 10-15 part, Caulis Spatholobi 10-30 part, Rhizoma Gastrodiae 3-10 part, Pheretima 5-15 part, Scorpio 2-5 part, Rhizoma Chuanxiong 3-10 part.
Further, the parts by weight of described each crude drug are preferably: Radix Clematidis 15 parts, Rhizoma Drynariae 10 parts, Herba Lycopodii 15 parts, Radix Angelicae Pubescentis 10 parts, Radix Stephaniae Tetrandrae 10 parts, Radix Aconiti 6 parts, Agkistrodon 10 parts, Zaocys 7 parts, Fructus Chaenomelis 15 parts, the Cortex Eucommiae 10 parts, Caulis Spatholobi 20 parts, 10 parts, Rhizoma Gastrodiae, Pheretima 10 parts, Scorpio 3 parts, Rhizoma Chuanxiong 10 parts.
Described Chinese medicine composition makes any one acceptable preparation clinically according to a conventional method, such as decoct, pill or capsule.According to the needs of different preparation, can choose and add corresponding customary adjuvant.
Preparation method and using method:
Pain phase decoct: in weight/volume, take Radix Clematidis 5-50g, Rhizoma Drynariae 10-15g, Herba Lycopodii 10-20g, Radix Angelicae Pubescentis 5-15g, Radix Stephaniae Tetrandrae 5-10g, Radix Aconiti 3-9g, Agkistrodon 1-15g, Zaocys 5-10g, Fructus Chaenomelis 10-15g, Cortex Eucommiae 10-15g, Caulis Spatholobi 10-30g, Rhizoma Gastrodiae 3-10g, Pheretima 5-15g, Scorpio 2-5g, Rhizoma Chuanxiong 3-10g, then this 15 taste Chinese medicine is put into marmite, first decocts the 600ml that adds water, soak 30min, use 30min at a simmer again after first boiling with high heat, taking liquid is about 350ml; Second decocts the 500ml that adds water, and use 25min at a simmer again after first boiling with high heat, taking liquid is about 350ml; Take at twice after decocting liquid medicine mixing two, sooner or later service once, decoction being taken warmly.
The pain relief phase is with honeyed pill, concentrated pill or capsule: take Radix Clematidis 15 parts, Rhizoma Drynariae 10 parts, Herba Lycopodii 15 parts, Radix Angelicae Pubescentis 10 parts, Radix Stephaniae Tetrandrae 10 parts, Radix Aconiti 6 parts, Agkistrodon 10 parts, Zaocys 7 parts, Fructus Chaenomelis 15 parts, the Cortex Eucommiae 10 parts, Caulis Spatholobi 20 parts, 10 parts, Rhizoma Gastrodiae, Pheretima 10 parts, Scorpio 3 parts, Rhizoma Chuanxiong 10 parts by weight ratio, then 100 orders or 120 mesh sieves are crossed after being pulverized by this 15 taste Chinese medicine, after making superfine medicated powder: 1. medicated powder and honey are made honeyed pill by 1:1.5 part by weight, every ball 3g, each serving 6g, every day takes twice; Or 2. medicated powder is loaded Capsules, every 0.3g, each serving 6, take three every day; Or 3. medicated powder is made concentrated pill by prior art processes, every 8 balls are equivalent to crude drug in whole 3g, each serving 8 balls, take three every day.
Pharmacology of the present invention is as follows:
Radix Clematidis: acrid in the mouth, salty.Warm in nature.Return urinary bladder channel.There is the merit of wind-damp dispelling, the meridian dredging, a fishbone or other bone caught in the throat that disappears.The pungent loose temperature of this product is led to, and property is apt to away suddenly, the current twelve regular channels, can wind-damp dispelling, and can stimulate the menstrual flow again stopping numbness pain.No matter all rheumatic arthralgia, apathy, all can use up and down, is rheumatic arthralgia key medicine.This product salty in the mouth, has softening the hard mass to disappear a fishbone or other bone caught in the throat effect.Modern pharmacological research proves: " this product has analgesic activity, and its vinegar liquid has certain emollescence to fish bony spur, and makes local of flaccid muscles, and impel bony spur to come off, its decoct has obvious antibacterial action etc.”
Rhizoma Drynariae: bitter in the mouth.Warm in nature.Return liver, kidney channel.There is the merit of invigorate blood circulation continuous wound, the kidney invigorating bone strengthening.The sweet temperature of this product enters Liver and kidney warp, have warming and recuperating the kidney-YANG, bone and muscle strengthening, benefit deficient, again can promoting the circulation of blood arteries and veins, reuniting the fractured tendons and bones, pain relieving of curing the wound.The diseases such as the damage for the treatment of tumbling down, lumbago due to renal deficiency flaccidity of the lower limbs.Modern pharmacological research proves: this product contains davallic acid, can promote that bone is to the absorption of calcium, and improve blood calcium and serum phosphorus levels, is conducive to the healing of fracturing; Also have some improvement chondrocyte function, the effect that postponement cell regeneration becomes and significantly analgesic activity etc.
Herba Lycopodii: bitter in the mouth, pungent.Warm in nature.Return Liver Channel.There is the merit of wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, treat rheumatic arthralgia, extremities joint is ached, activities adverse, munbness etc.
Radix Angelicae Pubescentis: acrid in the mouth, hardship.Slightly warm in nature.Return liver, urinary bladder channel.There is wind-damp dispelling, stopping numbness pain, the merit of inducing sweat.This product energy wind-damp dispelling, expelling cold and freeing bi, all anemofrigid-damp arthralgia all can be used.Because it is kind descending, be especially advisable with waist knee joint, lower limb joints of foot pain subordinate portion cold-damp severe one.Modern pharmacological research proves: this product has arthritis, eases pain and the effects such as the direct blood vessel dilating of energy.
Radix Stephaniae Tetrandrae: bitter in the mouth, pungent.Cold in nature.Return bladder, kidney, spleen channel.There is the merit of wind-damp dispelling, pain relieving, inducing diuresis to remove edema.This product is pungent can a surname fall apart, and bitter cold is fallen and let out, and energy wind-damp dispelling, heat clearing away removing obstruction in the collateral to relieve pain, be especially suitable for damp and hot inclined victor, disease sees that joint is tired of pain, joint stuffiness etc.
Radix Aconiti: acrid in the mouth, hardship.Warm in nature.GUIXIN, spleen, liver, kidney channel.There is the merit of expelling wind and removing dampness, dispersing cold for relieving pain.This product has stronger dispersing cold for relieving pain effect, controls headache due to cold-damp, general pain, severe and migratory arthralgia pain, unable to flex and stretch the extremities person.Modern pharmacological research proves: this product has the effects such as analgesia, calmness, local anesthesia, has consumption to zoopery arthritis.
Agkistrodon: sweet in the mouth, salty.Warm in nature.Return Liver Channel.There is the merit of dispelling wind and removing obstruction in the collateral, arresting convulsion relieving convulsion.This product dispels the wind power suddenly, again kind the meridian dredging, therefore for diseases such as rheumatoid arthritis stubborn, numb limbs and tense tendons, the contractures of muscle arteries and veins.
Zaocys: sweet in the mouth.Property is put down.Return Liver Channel.There is the merit of dispelling wind and removing obstruction in the collateral, arresting convulsion relieving convulsion.This product can search ailment said due to cold or exposure, saturating joint, dispelling the wind and dampness pathogens insensitive impediment, and brothers are slow can not stretch the diseases such as act.
Fructus Chaenomelis: sour in the mouth.Warm in nature.Return liver, spleen channel.There is the merit of relaxing muscles and tendons and activating QI and blood in the collateral, dehumidifying stomach function regulating.This product has good relaxing muscles and tendons and activating QI and blood in the collateral effect, and energy damp eliminating eliminating impediment, be the diseases such as the key medicine of lingering pathogenic wind insensitive impediment, spasm of muscles and vessels, dispelling the wind and dampness pathogens arthralgia pain, the contracture of muscle arteries and veins.Modern pharmacology experiment proves: this product has obvious detumescence effect to zoopery arthritis.
The Cortex Eucommiae: sweet in the mouth.Warm in nature.Return liver, kidney channel.There is the function such as invigorating the liver and kidney, bone and muscle strengthening.Therefore treatment liver, kidney deficiency soreness of waist and knee joint, lower limb wither soft wait disease." book on Chinese herbal medicine converges and says ": " void of all parts of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, the non-Cortex Eucommiae is not mended; The part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is wet, and the non-Cortex Eucommiae is unfavorable; The acid of foot shin, the non-Cortex Eucommiae is not gone; Waist knee joint is pain, and the non-Cortex Eucommiae is not removed.”
Caulis Spatholobi: bitter in the mouth, sweet.Warm in nature.Return Liver Channel.Have that promoting the circulation of blood is enriched blood, regulating menstruation, relaxing muscles and tendons and activating QI and blood in the collateral merit.The nourshing blood and promoting blood circulation of this product energy and relaxing muscles and tendons and activating QI and blood in the collateral, the diseases such as dispelling the wind and dampness pathogens arthralgia pain, arthralgia, numb limbs and tense tendons.
Rhizoma Gastrodiae: sweet in the mouth.Property is put down.Return Liver Channel.There is the merit of relieving spasm by subduing liver-wind, suppressing liver-YANG, dispelling wind and removing obstruction in the collateral.This product can be dispelled exogenous wind, the meridian dredging, the disease such as treatment wind apoplex involving the channels and collaterals, hands and feet caused by paralysis, numb limbs and tense tendons, spasm tic, again can dispelling the wind and dampness pathogens arthralgia pain, joint joint stuffiness person.
Pheretima: salty in the mouth.Cold in nature.Return liver, spleen, urinary bladder channel.There is the function such as clearing heat for calming endogenous wind, dredging collateral.This product is longer than current meridians, heat clearing away cold in nature, can treat the pyretic arthralgia of joint congestion and swelling pain, joint stuffiness, treats again the disease such as anemofrigid-damp arthralgia of limbs joint numb pain, joint stuffiness.
Scorpio: acrid in the mouth.Property is put down.Return Liver Channel.There is the merit of endogenous wind stopping relieving convulsion, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.This product both calmed down liver-wind, expel wind to dredge collateral pain relieving again, and to anemofrigid-damp arthralgia obstinate, the contracture of muscle arteries and veins, very then the insensitive impediment effect of joint deformity is rather good.
Rhizoma Chuanxiong: acrid in the mouth.Warm in nature.Return liver, gallbladder, pericardium channel.There is the merit of blood-activating and qi-promoting, wind-expelling pain-stopping.The pungent loose temperature of this product is led to, and can invigorate blood circulation, again can circulation of qi promoting, is " in blood gas medicine ", can " lower regulating menstruation water, middle relieving stagnation, the up head, bypass channels." expelling wind and activating blood circulation pain relieving, control limbs pain numbness, rheumatic Bi syndrome etc.
All medicine compatibilities above, play the merit of wind-damp dispelling, bone and muscle strengthening, dispelling cold by warming the meridian dredging collateral, spleen reinforcing kidney, benefiting essence-blood, promoting blood circulation, removing blood stasis and relieving pain altogether; Be used for the treatment of the evil numbness resistance meridians that wind and cold is damp and hot, qi-blood-body fluid is run not smooth, expectorant stasis of blood knot is also harmonious with exopathogen, go deep into the gonalgia caused by bone joint, joint stuffiness, upstairs, sit with squat down stand time pain increase the weight of, arthroncus, strong, distortion, touching difficulty such as to heal the disease.Chinese medicine composition of the present invention can promote that bony spur absorbs, and for a long time clothes can make that bony spur is softening, rust, and effective eliminate pain, clinical efficacy is remarkable.
Detailed description of the invention
Do to introduce in detail further to technical solution of the present invention below in conjunction with specific embodiment, but protection scope of the present invention is not limited thereto:
Embodiment 1
Radix Clematidis 5g, Rhizoma Drynariae 12g, Herba Lycopodii 10g, Radix Angelicae Pubescentis 15g, Radix Stephaniae Tetrandrae 7g, Radix Aconiti 9g, Agkistrodon 3g, Zaocys 5g, Fructus Chaenomelis 10g, Cortex Eucommiae 12g, Caulis Spatholobi 30g, Rhizoma Gastrodiae 3g, Pheretima 15g, Scorpio 5g, Rhizoma Chuanxiong 3g.
Pain phase decoct: above-mentioned 15 taste Chinese medicines are put into marmite, and first decocts the 600ml that adds water, soaks 30min, and use 30min at a simmer again after first boiling with high heat, taking liquid is about 350ml; Second decocts the 500ml that adds water, and use 25min at a simmer again after first boiling with high heat, taking liquid is about 350ml; Take at twice after decocting liquid medicine mixing two, sooner or later service once, decoction being taken warmly.
The pain relief phase is with honeyed pill, concentrated pill or capsule: cross 100 orders or 120 mesh sieves, after making superfine medicated powder after being pulverized by above-mentioned 15 taste Chinese medicines: 1. medicated powder and honey are made honeyed pill by 1:1.5 part by weight, every ball 3g, each serving 6g, every day takes twice; Or 2. medicated powder is loaded Capsules, every 0.3g, each serving 6, take three every day; Or 3. medicated powder is made concentrated pill by prior art processes, every 8 balls are equivalent to crude drug in whole 3g, each serving 8 balls, take three every day.
Embodiment 2
Radix Clematidis 15g, Rhizoma Drynariae 10g, Herba Lycopodii 15g, Radix Angelicae Pubescentis 10g, Radix Stephaniae Tetrandrae 10g, Radix Aconiti 6g, Agkistrodon 10g, Zaocys 7g, Fructus Chaenomelis 15g, Cortex Eucommiae 10g, Caulis Spatholobi 20g, Rhizoma Gastrodiae 10g, Pheretima 10g, Scorpio 3g, Rhizoma Chuanxiong 10g.
Preparation method and using method are with embodiment 1.
Embodiment 3
Radix Clematidis 50g, Rhizoma Drynariae 15g, Herba Lycopodii 20g, Radix Angelicae Pubescentis 5g, Radix Stephaniae Tetrandrae 5g, Radix Aconiti 3g, Agkistrodon 15g, Zaocys 10g, Fructus Chaenomelis 5g, Cortex Eucommiae 15g, Caulis Spatholobi 10g, Rhizoma Gastrodiae 7g, Pheretima 5g, Scorpio 21g, Rhizoma Chuanxiong 7g.
Preparation method and using method are with embodiment 1.
clinical trial
1.1 physical data
From year August in January, 2000 to 2013, filter out 120 routine kneecap arthritic patients.All cases is all made a definite diagnosis through health check-up and the multiple inspection such as X-ray or DR sheet, and without serious liver, kidney, core function badness.It is divided at random treatment group 60 example, wherein man 27 example, female 33 example, the age: 33-76 year, 60.5 years old mean age; Matched group 60 example, wherein man 29 example, female 31 example, the age: 35-75 year, 60 years old mean age.Two groups in sex, age, symptom etc. relatively all without significant difference (p ﹥ 0.05), there is comparability, refer to table 1.
A table 1 liang group case ordinary circumstance compares
Note: two groups are compared: p ﹥ 0.05
1.2 diagnostic criteria
1. knee joint damaged is had, damp and hot history of having a cold; 2. knee joint severe pain, joint stuffiness, enlargement, stiff, distortion; 3. body of the tongue purple is dim, tongue white, stringy and hesitant pulse; 4. the impact such as knee joint X-ray or DR or CT is learned and is checked prompting intercondyloid spine hypertrophy.
1.3 Therapeutic Method
Matched group: adopt western medicine routine treatment, analgesia Ibumetin Retavd or Sustained Release Tablet of Diclofenac Sodium; Stiff joint stuffiness is at Injection in knuckle articular cavity hyaluronic acid sodium, and shot 2ml, 1 time weekly, continuous 5 weeks is a course for the treatment of.
Treatment group: at matched group with on western medicine routine treatment basis, adds the embodiment of the present invention 2 prescription and preparation method thereof, using method.
Two groups treat 5 weeks respectively after, treat and forward and backwardly all carry out the inspection of DR sheet, observe intercondyloid spine hypertrophy or absorbing state and clinical symptoms and improve situation.
1.4 therapeutic evaluatioies:
1.4.1 effective: the gonalgia disappears, bend and stretch flexibly, upstairs or squat down pain and arthroncus when standing disappear, knee joint DR sheet observation: intercondyloid spine hypertrophy place rust.
1.4.2 effective: the gonalgia is alleviated, bend and stretch comparatively flexible, upstairs or pain relief when standing of squatting down, arthroncus disappears substantially, and knee joint DR sheet is observed: intercondyloid spine hypertrophy place slightly rust.
1.4.3 invalid: clinical symptoms is not improved, knee joint DR sheet is observed: intercondyloid spine hypertrophy place is without rust.
1.5 statistical method
Data rate represents, adopts x
2inspection, with p < 0.05 for difference, has statistical significance.
1.6 result
1.6.1 before and after treatment, two groups of symptoms improvement situations compare
Treatment group adds Chinese medicine composition of the present invention on matched group western medicine routine treatment basis, and clinical symptoms improvement rate (86%) is obviously better than matched group and uses merely western medicine routine treatment clinical symptoms improvement rate (48%), refers to table 2.
Before and after table 2 liang group treatment, clinical symptoms improves number of cases and improvement rate
Note: improve=effective+effectively
1.6.2 untoward reaction
Stomachache, acid regurgitation is there is in matched group after having 6 example analgesic.Treatment group does not find any untoward reaction.Anemia of pregnant woman is forbidden.
model case
Case 1
Yin so-and-so, man, 56 years old, peasant, Wang Dongshao people from village of Xi Xishao township, on July 19th, 2011, carried out inventor with " knee joint osseous arthritis " and locates to go to a doctor.Over 5 years, often there is double knee joint pain in patient, cold or tired rear pain increases the weight of whenever, heat or pain relief after having a rest.In nearly February, double knee joint pain exacerbates, once in the treatment of Nanyue County the People's Hospital Orthopaedics Clinic, and less effective, therefore come inventor place and seek medical advice.Disease is seen: double knee joint severe pain, can not walk, joint joint stuffiness, and pain when standing of often going upstairs or squat down increases the weight of, the light enlargement in joint, and local color of the leather is not red, and that touches is not hot, and the pain increased for cold or tired patella whenever; Pale tongue, white and thin fur, deep-slow pulse and string; DR sheet is pointed out: double knee joint intercondyloid spine hypertrophy.
Dialectical analysis: be affected by the cold wet heresy, and the cold victory partially of sense, cold main spasm, its property stagnates, and the resistance of QI and blood numbness is obstructed, therefore sees double knee joint severe pain.Lao Ze consumption hinders knee joint QI and blood, therefore after fatigue, the pain increased.Meet cold then blood more puckery, then pain increases very.Wind-cold damp pathogen keeps muscle, joint, then joint joint stuffiness.Cold being a kind of YIN pathogen, therefore joint silght enlargement, local color of the leather is not red, and that touches is not hot.Pale tongue, white and thin fur, deep and hesitant pulse and string is resembling of domination of cold.
Tcm diagnosis: numbness disease (arthralgia aggravated by cold).
The rule for the treatment of: wind-damp dispelling, bone and muscle strengthening, dispelling cold by warming the meridian dredging collateral, spleen reinforcing kidney, benefiting essence-blood, promoting blood circulation, removing blood stasis and relieving pain.
Side's medicine: the embodiment of the present invention 2 prescription, preparation method and using method.
Western medicine diagnose: two knee joint osseous arthritis.
Western medicine: alleviating pain Ibumetin Retavd, inject hyaluronic acid sodium respectively in two knee joint cavities, all the other give symptomatic treatment.
After treating 2 weeks, double knee joint pain obviously alleviates, and arthroncus disappears, pain relief when standing of going upstairs or squat down.Advise after taking continuously 5 weeks, double knee joint pain disappears, and goes upstairs or squat down when standing, or travel time is long slightly feels uncomfortable.Advise and continue to take honey pill agent half a year, taking symptomatology to March and disappear, there is not double knee joint pain, clinical cure after living in dry building yet, by repeatedly following up a case by regular visits to, so far without recurring.
Case 2
Fan so-and-so, female, 66 years old, peasant, bean people from village of Xi Sizhuan township, on June 12nd, 2012, carried out inventor with " two knee joint osseous arthritis " and locates to go to a doctor.Patient is over 6 years, double knee joint pain, recurrent exerbation, whenever rainy weather have a bath or after fatigue then double knee joint the pain increased, once arrive the many places treatments such as Nanyue County the People's Hospital Orthopaedics Clinic and Zhengzhou City Orthopedic Hospital, less effective, therefore come inventor place and seek medical advice.Disease is seen: double knee joint has an intense pain, swelling, muscular soreness, and two lower limb weigh, and two foot pains are numb with big toe; Light red tongue, tongue is greasy in vain, relaxed and soft pulse; DR sheet is pointed out: two knee joint intercondyloid spine hypertrophy.
Dialectical analysis: be affected by the cold wet heresy, and feel damp and partially win, cold-dampness numbness, QI and blood is obstructed, therefore double knee joint sharp ache and swelling.Because of damp pathogen being sticky and stagnant in nature, deep, wet note meridians, muscle of being detained, joint, QI-blood circulation is obstructed, then see that double knee joint swells, ache, joint stuffiness.Skin channels is turbid damp retardance, and nutrient blood runs smooth, and sees two vola portions and big toe numbness.Overcast and rainy or wet Sheng of having a bath, therefore the pain increased.Fatigue is wasting QI-blood then, therefore pain increases.What light red tongue, white and thin fur, relaxed and soft pulse were that damp contains partially resembles.
Tcm diagnosis: numbness disease (damp arthralgia).
The rule for the treatment of: wind-damp dispelling, bone and muscle strengthening, dispelling cold by warming the meridian dredging collateral, spleen reinforcing kidney, benefiting essence-blood, promoting blood circulation, removing blood stasis and relieving pain.
Side's medicine: the embodiment of the present invention 2 prescription, preparation method and using method.
Western medicine diagnose: two knee joint osseous arthritis.
Western medicine: alleviating pain Sustained Release Tablet of Diclofenac Sodium, inject hyaluronic acid sodium respectively in two knee joint cavities, all the other give symptomatic treatment.
After treating 10 days, double knee joint pain obviously alleviates, and knee joint part swelling disappears, and muscular soreness and two edeam of legs to feel and alleviated, two volas and big toe numbness.After advising continuously treatment 6 weeks, double knee joint pain disappears, and muscular soreness disappears, two lower limb heavy, two volas disappear substantially with big toe numbness, the recovery of tongue, arteries and veins is normally.Advise and continue to take honey pill agent half a year, take symptomatology to February and disappear, there is not pain in normal activity double knee joint, clinical cure, by repeatedly following up a case by regular visits to, so far without recurring.
Claims (6)
1. treat the arthropathic Chinese medicine composition of kneecap, it is characterized in that being made up of each crude drug of following portions by weight: Radix Clematidis 5-50 part, Rhizoma Drynariae 10-15 part, Herba Lycopodii 10-20 part, Radix Angelicae Pubescentis 5-15 part, Radix Stephaniae Tetrandrae 5-10 part, Radix Aconiti 3-9 part, Agkistrodon 1-15 part, Zaocys 5-10 part, Fructus Chaenomelis 10-15 part, Cortex Eucommiae 10-15 part, Caulis Spatholobi 10-30 part, Rhizoma Gastrodiae 3-10 part, Pheretima 5-15 part, Scorpio 2-5 part, Rhizoma Chuanxiong 3-10 part.
2. the arthropathic Chinese medicine composition for the treatment of kneecap as claimed in claim 1, is characterized in that being made up of each crude drug of following portions by weight: Radix Clematidis 15 parts, Rhizoma Drynariae 10 parts, Herba Lycopodii 15 parts, Radix Angelicae Pubescentis 10 parts, Radix Stephaniae Tetrandrae 10 parts, Radix Aconiti 6 parts, Agkistrodon 10 parts, Zaocys 7 parts, Fructus Chaenomelis 15 parts, the Cortex Eucommiae 10 parts, Caulis Spatholobi 20 parts, 10 parts, Rhizoma Gastrodiae, Pheretima 10 parts, Scorpio 3 parts, Rhizoma Chuanxiong 10 parts.
3. the arthropathic Chinese medicine composition for the treatment of kneecap as claimed in claim 1 or 2, is characterized in that: make any one acceptable preparation clinically according to a conventional method.
4. the arthropathic Chinese medicine composition for the treatment of kneecap as claimed in claim 3, is characterized in that: described preparation is decoct, honeyed pill, concentrated pill or capsule.
5. treat the preparation method of the arthropathic Chinese medicine composition of kneecap for one kind, it is characterized in that: in weight/volume, take Radix Clematidis 5-50g, Rhizoma Drynariae 10-15g, Herba Lycopodii 10-20g, Radix Angelicae Pubescentis 5-15g, Radix Stephaniae Tetrandrae 5-10g, Radix Aconiti 3-9g, Agkistrodon 1-15g, Zaocys 5-10g, Fructus Chaenomelis 10-15g, Cortex Eucommiae 10-15g, Caulis Spatholobi 10-30g, Rhizoma Gastrodiae 3-10g, Pheretima 5-15g, Scorpio 2-5g, Rhizoma Chuanxiong 3-10g, then this 15 taste Chinese medicine is put into marmite, first decocts the 600ml that adds water, soak 30min, 30min at a simmer is used again after first boiling with high heat, taking liquid 350ml, second decocts the 500ml that adds water, and uses 25min at a simmer again, taking liquid 350ml after first boiling with high heat, namely decoct is made after decocting liquid medicine mixing two.
6. treat the preparation method of the arthropathic Chinese medicine composition of kneecap for one kind, it is characterized in that: take Radix Clematidis 15 parts, Rhizoma Drynariae 10 parts, Herba Lycopodii 15 parts, Radix Angelicae Pubescentis 10 parts, Radix Stephaniae Tetrandrae 10 parts, Radix Aconiti 6 parts, Agkistrodon 10 parts, Zaocys 7 parts, Fructus Chaenomelis 15 parts, the Cortex Eucommiae 10 parts, Caulis Spatholobi 20 parts, 10 parts, Rhizoma Gastrodiae, Pheretima 10 parts, Scorpio 3 parts, Rhizoma Chuanxiong 10 parts by weight ratio, then 100 orders or 120 mesh sieves are crossed after being pulverized by this 15 taste Chinese medicine, after making superfine medicated powder: 1. medicated powder and honey are made honeyed pill by 1:1.5 part by weight, every ball 3g; Or 2. medicated powder is loaded Capsules and make capsule, every 0.3g; Or 3. medicated powder is made concentrated pill by prior art processes, every 8 balls are equivalent to crude drug in whole 3g.
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