CN102626449A - Capsule for treating apoplexy hemiplegia - Google Patents
Capsule for treating apoplexy hemiplegia Download PDFInfo
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Abstract
The invention relates to a drug combination, specifically relates to a medicine, which is prepared by adopting traditional Chinese medicines as raw materials, for treating a series of cardiovascular and cerebrovascular diseases, such as apoplexy hemiplegia, hypertension, hyperlipidemia, high blood viscosity and the like. Specifically, the medicine is prepared by adopting astragalus, leech, scorpio, nux vomica, antler, borneol, angelica sinensis, szechuan lovage rhizome, red paeony root , Chinese-drug-saffron, frankincense, myrrh, lumbricus, cassia twig, garter snake, radix aconiti preparata, radix aconiti kusnezoffii praeparata and radix aconiti lateralis preparata as the raw materials according to a certain proportion and grinding the raw materials into herb powder. The medicine provided in the invention can activate qi and blood, promote blood circulation, reduce blood viscosity, reduce blood consistency, reduce blood concentration and reduce blood accumulation, suppress synthesis and absorption of cholesterol and triglyceride, soften blood vessels, and recover vascular elasticity, and has other effects. At the same time, the medicine is simple to prepare, has low cost, is beneficial for popularization, and is safe and free of toxic or side effects.
Description
Technical field
The present invention relates to a kind of drug regimen, specifically is the medicine with a series of cardiovascular and cerebrovascular diseases such as treatment apoplectic hemiplegia, hypertension, hyperlipidemia, high blood viscosity of raw material with Chinese medicine, belongs to the field of Chinese medicines.
Background technology
Hemiplegia is claimed hemiplegia again, is a kind of common difficult miscellaneous diseases, is the sequela of apoplexy.The so-called acute cerebrovascular disease of doctor trained in Western medicine is the apoplexy said of the traditional Chinese medical science just, and the symptom performance mainly is a side limb adynamia, numbness, and is movable ineffective, sometimes with symptoms such as dizziness, slurred speeches.Its main diseases is because of being that, some secondary factors unusual by blood viscosity increase, hemodynamic abnormalities, blood constituent and cerebral arteries pathological changes cause.The sickness rate of apoplexy, mortality rate and disability rate are all quite high, are one type of diseases that has a strong impact on human health.
The frequent people who participates in the whirl of society, because high fat kind food, cigarette, the capacity for liquor taken in increase, the probability of therefore suffering from a series of cardiovascular and cerebrovascular diseases such as hypertension, hyperlipidemia, high blood viscosity increases greatly.In China, the sickness rate of apoplexy is annual per 100,000 population 189-219 example.Sickness rate increased with the age, and about 72% apoplexy first occurs in the old people of over-65s.The mortality rate of apoplexy is annual per 100,000 population 116-142 example, is first causes of the death in many areas.According to World Health Organization (WHO) statistics, annual China has more than 200 ten thousand people to die from apoplexy approximately, and in the up to ten million apoplexy survivor, wherein 70% will bear sequela such as hemiplegia, hand and foot numbness, aphasis, dementia throughout one's life misery.At present, China is used to treat the expense of cerebrovascular every year and estimates to be about more than 120 hundred million yuan, adds various indirect economic loss, nearly 20,000,000,000 yuan of annual total expenditure.
The western medical treatment apoplexy mainly adopts Drug therapy and operative treatment, does not have the notion of blood circulation promoting and blood stasis dispelling, does not also have the medicine of blood circulation promoting and blood stasis dispelling, therefore has no idea to dispel congestion or clot.At present doctor trained in Western medicine to cerebral infarction mainly adopt thrombolytic, fall fibre, Therapeutic Method such as anticoagulant, brain protection, but most of patient has lost the best opportunity of thrombolytic when coming hospital.Cerebral hemorrhage mainly adopts and falls cranium pressure, complication prevention and surgical operation therapy; The theory of the method medication of doctor trained in Western medicine " dredging vascellum " mainly is vasodilation, anticoagulant therapy and nutrition treatment; Be exactly extractant in addition with Chinese medicine; Radix Salviae Miltiorrhizae, Flos Carthami, Folium Ginkgo extractant are supplying the defective that Western medicine can not blood circulation promoting and blood stasis dispelling, but these curative effects are unsatisfactory.
And the traditional Chinese medical science thinks that apoplexy is the card of deficiency in origin and excess in superficiality, is preponderance of either YIN or YANG at this, and mechanism of qi is disorderly contrary; Be designated as fire and wind stirring up each other, expectorant is turbid to be jammed blood-stasis internal-depression.Its disease such as treatment apoplectic hemiplegia etc. is mainly adopted acupuncture, the three kinds of methods of massaging, take traditional Chinese medicine, and the above two only are adapted at convalescent care, are having no way of doing it in early stage; And the latter takes traditional Chinese medicine, and all is faced with difficult problems such as treatment cycle is long, therapeutic effect is not remarkable at currently marketed prescriptions of Chinese medicine.Therefore the inventor sums up Cai Shi clan diagnoses and treatment, combines oneself year clinical position experience surplus 40, and through test, research for many years, " hemiplegia capsule " comes out finally.
Summary of the invention
The object of the invention just provides a kind of Chinese medicine with a series of cardiovascular and cerebrovascular disease functions such as treatment apoplectic hemiplegia, hypertension, hyperlipidemia, high blood viscosity.
Capsule of the present invention, it is to be processed by following scheme by the Radix Astragali, Hirudo, Scorpio, Semen Strychni, Cornu Cervi Pantotrichum, Borneolum Syntheticum, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Flos Carthami, Olibanum, Myrrha, Pheretima, Ramulus Cinnamomi, Zaocys, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Radix Aconiti Lateralis Preparata:
(1) medicine each component consumption of the present invention is: Radix Astragali 70-90g, Hirudo 30-50g, Scorpio 15-35g, Semen Strychni 5-7g, Cornu Cervi Pantotrichum 5-7g, Borneolum Syntheticum 1-3g, Radix Angelicae Sinensis 20-40g, Rhizoma Chuanxiong 40-60g, Radix Paeoniae Rubra 10-30g, Flos Carthami 20-40g, Olibanum 4-16g, Myrrha 5-15g, Pheretima 20-40g, Ramulus Cinnamomi 10-30g, Zaocys 40-60g, Radix Aconiti Preparata 10-30g, Radix Aconiti Kusnezoffii Preparata 10-30g, Radix Aconiti Lateralis Preparata 10-30g;
(2) with said medicine with the radioactive element illumination-based disinfection, it is for use that the cleaning and removing impurities crushed after being dried is crossed 20～40 mesh sieves respectively;
(3) each group raw material powder is minced fully with even, is ground into fine flour, the 1g capsule of packing into, " Cai Shi hemiplegia capsule ".Get 3g during treatment, be a course of treatment at twice, 7 day every day at every turn.
The present invention is the basis with the Cai Shi secret prescription handed down in the family from generation to generation, draws the length of Chinese medicine, in conjunction with modern advanced biological medicine means, through studying a kind of oral capsule of treating hemiplegia of research and development for a long period of time.
Capsule of the present invention, wherein sweet, the tepor of Radix Astragali nature and flavor is returned lung, spleen, liver, kidney channel, and benefiting QI for strengthening the superficies is arranged, and arresting sweating takes off admittedly, holder skin ulcer granulation promoting, the effect of inducing diuresis to remove edema.It is weak to be used to treat the deficiency of vital energy, sinking of QI of middle-JIAO, and the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating is given birth to consolidating superficial resistance holder skin ulcer." herbal classic " cloud: " Radix Astragali can lead to blood circulation regulating, popular meridians.”
Hirudo salty in the mouth, hardship, property is flat poisonous.Return Liver Channel, urinary bladder channel, removing blood stasis, removing blood stasis are arranged, the effect of stimulating the menstrual flow cures mainly blood-retention, lump in the abdomen stomachache, and traumatic blood stasis is had a pain, the menstruation apolipsis, diseases such as carbuncle erysipelas have the treatment apoplexy, hypertension, the clear stasis of blood, amenorrhea, effects such as traumatic injury.In recent years new discovery Hirudo preparation has specially good effect at control cardiovascular and cerebrovascular disease and anticancer aspect.Later age, Zhang Xichun praised this medicine: " deposit blood stasis and do not hinder fresh blood, the elite of pure lines water generates, and is at all harmless in edema caused by disorder of QI, and blood stasis is silently in invisible, and true good medicine also ".Hirudo ability activation fibrinolytic system, thrombus.Hirudin is formed with obvious inhibitory action to experimental thrombosis, and the experimental phlebothrombosis due to the thrombin is had dissolution.Hirudo has the effect of expansion blood capillary, microcirculation improvement, increase renal blood flow amount.Hirudo has the effect of expansion peripheral blood vessel, blood flow increasing and minimizing vascular resistance.
Scorpio acrid in the mouth, property are put down, and be poisonous.Ability endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Be used for infantile convulsion, the tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Semen Strychni bitter in the mouth, cold in nature, poisonous, return liver, spleen channel, removing obstruction in the collateral to relieve pain is arranged, the effect of mass dissipating and swelling eliminating.Be used for traumatic injury, fracture swells and ache, rheumatoid arthritis stubborn, paralysis and numbness, skin sore, laryngopharynx swelling and pain.
Cornu Cervi Pantotrichum sweet in the mouth, salty, warm in nature, return kidney, Liver Channel.Invigorating kidney-YANG is arranged, mend marrow, bone and muscle strengthening is transferred to dash and is appointed, effects such as holder sore.Cure mainly and suffer from a deficiency of the kidney, dizziness, deafness, order is dark, sexual impotence, spermatorrhea, cold womb is infertile, weakness and emaciation, Mental fatigue, fear of cold, the spinal column cold type of pain, the muscles and bones flaccidity is soft, disease such as bleeding not during menses, carbuncle of yin nature are not held back and prolonged illness is deficient.
The Borneolum Syntheticum acrid in the mouth is bitter, and is cool in nature, GUIXIN, spleen, lung meridian.The refreshment of having one's ideas straightened out is arranged, the effect of clearing away heat to alleviate pain.Be used for calentura coma, convulsions, the apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, the attacked by pestiferous factors stupor, obstruction of qi in the chest and cardialgia, conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Radix Angelicae Sinensis is warm in nature, and is ignorant sweet, hot, returns liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, the amenorrhea dysmenorrhea, asthenia cold abdominalgia, the dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores, the apoplexy syncope is spat out white foams, puerperal paralysis.Anti-hypoxia is arranged, regulate body's immunity, anticancer, improve looks, enrich blood and invigorate blood circulation, antibacterial, effects such as arteriosclerosis.
The Rhizoma Chuanxiong acrid in the mouth, warm in nature, return liver, gallbladder, pericardium channel.The effect that blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping are arranged.Medicine first choice of the treatment headache, to menoxenia, the amenorrhea dysmenorrhea, puerperal, the stasis of blood stagnated raw meat bitterly, the lump in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc. can both play effect.
The Radix Paeoniae Rubra bitter in the mouth, cold nature is returned Liver Channel.The ability clearing away heat and cooling blood, eliminating stasis to stop pain.Be used for thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass stomachache, injury from falling down, carbuncle skin infection.
Flos Carthami is warm in nature, acrid in the mouth, GUIXIN, Liver Channel.Can invigorate blood circulation latus rectum, eliminating stasis to stop pain.Be used for amenorrhea, dysmenorrhea, lochia is not all right, lump in the abdomen mass in the abdomen, traumatic injury.Be suitable for various varicosis, peripheral neuritis, blood circulation is bad, lower limb numbness or congestion such as livid purple.
The Olibanum acrid in the mouth is bitter, and is warm in nature, GUIXIN, liver, spleen channel.The analgesic therapy of invigorating blood circulation, the effect of detumescence and promoting granulation.Be used for obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, addiction abdominal mass stomachache, rheumatic arthralgia, the contracture of muscle arteries and veins, traumatic injury, carbuncle skin infection.
The Myrrha acrid in the mouth is bitter, and property is flat, GUIXIN, liver, spleen channel.The diffusing blood blood stasis removing of ability, subduing swelling and relieving pain.Can control traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.
Pheretima is claimed Lumbricus again, and Pheretima salty in the mouth cold in nature is returned liver, spleen, urinary bladder channel.Function is heat clearing away, spasmolytic, Zhichuan, diuresis.Cure mainly that hyperpyrexia is manic, convulsion with spasms, headache conjunctival congestion, the diseases such as expectorant heat, apoplexy, hemiplegia of panting.
Ramulus Cinnamomi acrid in the mouth, sweet, warm in nature, GUIXIN, lung, urinary bladder channel.Ability diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Be used for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Zaocys sweet in the mouth, property are put down, and be nontoxic, returns Liver Channel.Dispel the wind, active, the effect of arresting convulsion.Be used for rheumatoid arthritis stubborn, numbness contracture, middle air port eye fish sticking its mouth out of the water tiltedly, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
System river, Radix Aconiti Kusnezoffii acrid in the mouth, hardship, hot in nature, poisonous, GUIXIN, liver,kidney,spleen warp.The ability expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Radix Aconiti Lateralis Preparata acrid in the mouth, sweet, extremely hot in nature, poisonous, GUIXIN, kidney, spleen channel.The ability recuperating depleted YANG and rescuing the patient from collapse, it is supporing yang to mend fire, dispersing cold for relieving pain.Be used for the YANG-depletion collapse, the cold extremities faint pulse, deficiency of heart-YANG, obstruction of qi in the chest and cardialgia, deficiency and coldness is vomited and diarrhoea, coldness and pain in the epigastrium, kidney yang deficiency, sexual impotence cold womb, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
The principle that counteracts each other according to Chinese medicine makes up the work effect of QI and blood of performance effectively with these medicines, blood circulation promoting, reduce blood sticking, thick, dense, gather state, inhibition cholesterol; Triglyceride is synthetic and absorb vessel softening, recovery blood vessel elasticity; The anticoagulant factor and hematoblastic gathering stops intravascular coagulation, dredges the inside pipe wall alienation thing that purifies the blood; Recover the cerebral tissue blood supply, recover body function and consciousness function comprehensively, thereby reach the dual purpose of treating both the principal and secondary aspects of a disease and prevention of recurrence.
The specific embodiment
Embodiment one
Capsule of the present invention, it is to be processed by following scheme by the Radix Astragali, Hirudo, Scorpio, Semen Strychni, Cornu Cervi Pantotrichum, Borneolum Syntheticum, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Flos Carthami, Olibanum, Myrrha, Pheretima, Ramulus Cinnamomi, Zaocys, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Radix Aconiti Lateralis Preparata:
(1) medicine each component consumption of the present invention is: Radix Astragali 70g, Hirudo 30g, Scorpio g, Semen Strychni 5g, Cornu Cervi Pantotrichum 5g, Borneolum Syntheticum 1g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 40g, Radix Paeoniae Rubra 10g, Flos Carthami 20g, Olibanum, each 5g of Myrrha, Pheretima 20g, Ramulus Cinnamomi 10g, Zaocys 40g, Radix Aconiti Preparata 10g, Radix Aconiti Kusnezoffii Preparata 10g, Radix Aconiti Lateralis Preparata 10g;
(2) with said medicine with the radioactive element illumination-based disinfection, it is for use that the cleaning and removing impurities crushed after being dried is crossed 20～40 mesh sieves respectively;
(3) each group raw material powder is minced fully with even, is ground into fine flour, the 1g capsule of packing into, " Cai Shi hemiplegia capsule ".Get 3g during treatment, be a course of treatment at twice, 7 day every day at every turn.
Embodiment two
(1) medicine each component consumption of the present invention is: Radix Astragali 80g, Hirudo 40g, Scorpio 25g, Semen Strychni 6g, Cornu Cervi Pantotrichum 6g, Borneolum Syntheticum 2g, Radix Angelicae Sinensis 30g, Rhizoma Chuanxiong 50g, Radix Paeoniae Rubra 20g, Flos Carthami 30g, Olibanum, each 10g of Myrrha, Pheretima 30g, Ramulus Cinnamomi 20g, Zaocys 50g, system river, each 20g of Radix Aconiti Kusnezoffii, Radix Aconiti Lateralis Preparata 20g;
(2) with said medicine with the radioactive element illumination-based disinfection, it is for use that the cleaning and removing impurities crushed after being dried is crossed 20～40 mesh sieves respectively;
(3) each group raw material powder is minced fully with even, is ground into fine flour, the 1g capsule of packing into, " Cai Shi hemiplegia capsule ".Get 3g during treatment, be a course of treatment at twice, 7 day every day at every turn.
Embodiment three
(1) medicine each component consumption of the present invention is: Radix Astragali 90g, Hirudo 50g, Scorpio 35g, Semen Strychni 7g, Cornu Cervi Pantotrichum 7g, Borneolum Syntheticum 3g, Radix Angelicae Sinensis 40g, Rhizoma Chuanxiong 50g, Radix Paeoniae Rubra 30g, Flos Carthami 40g, Olibanum, each 15g of Myrrha, Pheretima 40g, Ramulus Cinnamomi 30g, Zaocys 60g, system river, each 30g of Radix Aconiti Kusnezoffii, Radix Aconiti Lateralis Preparata 30g;
(2) with said medicine with the radioactive element illumination-based disinfection, it is for use that the cleaning and removing impurities crushed after being dried is crossed 20～40 mesh sieves respectively;
(3) each group raw material powder is minced fully with even, is ground into fine flour, the 1g capsule of packing into, " Cai Shi hemiplegia capsule ".Get 3g during treatment, be a course of treatment at twice, 7 day every day at every turn.
Clinical trial
In order to verify the good effect of the present invention's " Cai Shi hemiplegia capsule ", the inventor entrusts Zhengzhou University to carry out a large amount of animals and clinical experiment, selects the part test report as follows at present.
Test Example 1 capsule of the present invention is to the influence of Rats Organs and Tissues coefficient
One, physical data
1, laboratory animal source: 80 of the self-produced SD rats of Zhengzhou University, body weight 60～80g is divided into four groups at random, and 20 every group, male and female half and half, single cage is raised.
Two, test method
(1) animal subject is established three dose groups (3ml/kg body weight, 3ml/kg body weight, 12ml/kg body weight) and a matched group (distilled water filling stomach), irritates stomach, continuous 30 days for respectively each dose groups animal subject medicine.The equal feed normal feedstuff of each treated animal of duration of test, and ad lib, drinking-water.Experiment finishes the back and puts to death rat, and liver,kidney,spleen etc. is carried out histopathologic examination's (paraffin section).
Three, result of the test
The dirty body ratio of each treated animal of table 1 result (%)
Can find out that from table 1 all animal liver, spleen, kidney etc. are not all seen obvious pathological change, explain this capsule have no side effect, safe and reliable, harmless.
Test Example 2 capsules of the present invention improve the effect of apoplectic hemiplegia
One, physical data
Acute cerebral thrombosis diagnostic criteria or " the nineteen ninety-five People's Republic of China's Chinese medicine industry standard traditional Chinese medical science disease diagnosis criterion of therapeutical effect " diagnostic criteria of ischemia apoplexy and exclusion standard by the 4th the cerebrovascular disease academic conference revision in the whole nation; Person's 185 examples that are diagnosed as the acute cerebral thrombosis are all from first Affiliated Hospital of Zhengzhou University.Successively be divided into two groups at random by being admitted to hospital, i.e. hemiplegia capsule for treating group (A organizes 93 examples), Western medicine colligation matched group (B organizes 92 examples).Male's 103 examples in the patient who accomplishes overall process, women's 82 examples; Age reckling 45 years old, the oldest person 80 years old, 63.57 years old mean age; Each joint and whole human body function damage percent zero difference (P＞0.5) through between the statistical procedures group had comparability (seeing table 1) before the experimenter treated.
Each joint and whole human body function damage percent % were relatively before table 2 a liang group experimenter treated
Two, test method
A group adopts this hemiplegia capsule for treating, gets 3g at every turn, serve on 7 days every day twice, rises in the 8th day to take medicine every day once, serve on 30 days, treats altogether 37 days.
The B group adopts Western medicine colligation method therapeutic scheme: mannitol+low molecular dextran+citicoline+TCNS therapy+body sense neuromuscular promotes therapy.Its treatment flow process is: the first step, the about 30min of intravenous drip mannitol; Second step, intravenous drip low molecular dextran 250ml and 0.9% normal saline 150ml+ citicoline 0.5g, about 2h; The 3rd step, TCNS therapy for treating hemiplegia limb 30min; In the 4th step, body sense neuromuscular promotes therapy for treating hemiplegia limb 20min.According to the state of an illness, when obvious intracranial hypertension is arranged, can increase by 1 group of mannitol.
First and second went on foot and treated totally 10 days equal every day 1 time B group course of treatment; Third and fourth step was treated totally 30 days every day 1 time since the 8th day; Treated altogether 37 days.
Observation of curative effect
Index detect with before the joint angles instrumentation amount patient treatment with treat back porch, wrist, hip, knee joint, each functional perspective of ankle joint.
2. efficacy assessment standard is with reference to American Medical Association's " permanent sick evaluation guide that decreases " assessment method (GEPI); Measure before the treatment and back porch, wrist, hip, knee joint, each functional perspective of ankle joint, and pass judgment on its hemiplegia limb function and whole human body function damage percentage rate situation.
3. table 3 is seen in two groups of influences to each joint and whole human body function damage percent.
Each joint and whole human body function damage percent % were relatively before and after table 3 a liang group experimenter treated
Annotate: * * self compares P＜0.01 with treatment is preceding; Compare △ △ P＜0.01 with the B group.
Visible from table 3, self more all can obviously reduce each joint and whole human body function damage percentage rate before and after two groups of treatments, with comparing difference before the treatment utmost point clear meaning (P＜0.01) is arranged.Compare between two groups of treatment back groups: the hemiplegia Capsules group can obviously reduce shoulder, wrist, hip, knee joint, ankle joint and whole human body function damage percentage rate, with the matched group comparing difference utmost point significance meaning (P＜0.01) is arranged all.
Conclusion
Show that through animal and clinical test results " hemiplegia capsule " can not be taken care of oneself hypertension to treatment apoplectic hemiplegia, upper and lower extremities; Hyperlipidemia, a series of cardiovascular and cerebrovascular diseases such as high blood viscosity, evident in efficacy; Taking convenience, and in the test testing process, do not find obvious adverse reaction and toxic and side effects.
Claims (4)
1. capsule of treating apoplectic hemiplegia is characterized in that this capsule is made up of following raw material medicaments: Radix Astragali 70-90g, Hirudo 30-50g, Scorpio 15-35g, Semen Strychni 5-7g, Cornu Cervi Pantotrichum 5-7g, Borneolum Syntheticum 1-3g, Radix Angelicae Sinensis 20-40g, Rhizoma Chuanxiong 40-60g, Radix Paeoniae Rubra 10-30g, Flos Carthami 20-40g, Olibanum 4-16g, Myrrha 5-15g, Pheretima 20-40g, Ramulus Cinnamomi 10-30g, Zaocys 40-60g, Radix Aconiti Preparata 10-30g, Radix Aconiti Kusnezoffii Preparata 10-30g, Radix Aconiti Lateralis Preparata 10-30g.
2. pharmaceutical composition according to claim 1, wherein the consumption of each crude drug is:
Radix Astragali 80g, Hirudo 40g, Scorpio 25g, Semen Strychni 6g, Cornu Cervi Pantotrichum 6g, Borneolum Syntheticum 1g, Radix Angelicae Sinensis 30g, Rhizoma Chuanxiong 50g, Radix Paeoniae Rubra 20g, Flos Carthami 30g, Olibanum 10g, Myrrha 10g, Pheretima 30g, Ramulus Cinnamomi 20g, Zaocys 50g, Radix Aconiti Preparata 20g, Radix Aconiti Kusnezoffii Preparata 20g, Radix Aconiti Lateralis Preparata 20g.
3. according to claim 1 and 2 described pharmaceutical compositions, its preparation scheme is following:
A) take by weighing the Radix Astragali, Hirudo, Scorpio, Semen Strychni, Cornu Cervi Pantotrichum, Borneolum Syntheticum, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Flos Carthami, Olibanum, Myrrha, Pheretima, Ramulus Cinnamomi, Zaocys, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Radix Aconiti Lateralis Preparata with the radioactive element illumination-based disinfection by each component, it is for use that the cleaning and removing impurities crushed after being dried is crossed 20～40 mesh sieves respectively;
B) just respectively organize raw material powder and mince fully, be ground into fine flour with even, the 1g capsule of packing into, get final product said pharmaceutical composition.
4. according to claim 1 and 2 described pharmaceutical compositions, each 3g, every day 2 times.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836189A (en) * | 2012-09-10 | 2012-12-26 | 李小杵 | Medicine for treating hemiplegia |
| CN102836412A (en) * | 2012-09-26 | 2012-12-26 | 杨高林 | Chinese medicinal composition for treating idiopathic facial paralysis and preparation method thereof |
| CN106177231A (en) * | 2016-07-08 | 2016-12-07 | 刘福坤 | A kind of method utilizing five kinds of skill of handling needles to coordinate treatment by Chinese herbs plant man |
| CN107961342A (en) * | 2018-01-25 | 2018-04-27 | 衣跃利 | A kind of Chinese medicine composition for treating hemiplegia and preparation method thereof |
| CN113082191A (en) * | 2021-05-12 | 2021-07-09 | 卢文刚 | Preparation for effectively treating myocardial infarction hemiplegia and preparation method thereof |
| CN114848714A (en) * | 2022-06-17 | 2022-08-05 | 新乡医学院第一附属医院 | Collateral-dredging and rejuvenating ointment and preparation method thereof |
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| CN102836189A (en) * | 2012-09-10 | 2012-12-26 | 李小杵 | Medicine for treating hemiplegia |
| CN102836412A (en) * | 2012-09-26 | 2012-12-26 | 杨高林 | Chinese medicinal composition for treating idiopathic facial paralysis and preparation method thereof |
| CN106177231A (en) * | 2016-07-08 | 2016-12-07 | 刘福坤 | A kind of method utilizing five kinds of skill of handling needles to coordinate treatment by Chinese herbs plant man |
| CN107961342A (en) * | 2018-01-25 | 2018-04-27 | 衣跃利 | A kind of Chinese medicine composition for treating hemiplegia and preparation method thereof |
| CN113082191A (en) * | 2021-05-12 | 2021-07-09 | 卢文刚 | Preparation for effectively treating myocardial infarction hemiplegia and preparation method thereof |
| CN114848714A (en) * | 2022-06-17 | 2022-08-05 | 新乡医学院第一附属医院 | Collateral-dredging and rejuvenating ointment and preparation method thereof |
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