CN1281236C

CN1281236C - Chinese medicinal decoction for treating embolus disease

Info

Publication number: CN1281236C
Application number: CN 200310114436
Authority: CN
Inventors: 杨清富
Original assignee: Individual
Current assignee: Individual
Priority date: 2003-12-07
Filing date: 2003-12-07
Publication date: 2006-10-25
Anticipated expiration: 2023-12-07
Also published as: CN1623582A

Abstract

The present invention provides a Chinese medicinal decoction for treating thrombosis. The present invention is characterized in that the active ingredient of the Chinese medicinal decoction for treating thrombosis is prepared from the following raw materials of the proportion by dosage: 5 to 30 grams of ginseng, 20 to 50 grams of milkvetch roots, 10 to 30 grams of angelica, 10 to 30 grams of chuanxiong rhizomes, 10 to 30 grams of unpeeled CORTEX MOUTAN, 10 to 30 grams of Flos Carthami, 10 to 30 grams of red peony roots or Radix Paeoniae Alba, 10 to 30 grams of cassia bark, 20 to 60 grams of Flos Lonicerae or CAULIS LONICERAE, 10 to 30 grams of coptis roots or scutellaria roots, 10 to 30 grams of oriental waterplantain rhizomes, 10 to 30 grams of licorice roots and 10 to 30 grams of Squama Manis, wherein the ginseng and the milkvetch roots have the functions of invigorating qi and yang, strengthening body resistance and eliminating pathogen, the angelica, the chuanxiong rhizomes, the unpeeled CORTEX MOUTAN, the Flos Carthami, the red peony roots or the Radix Paeoniae Alba have the functions of promoting blood circulation and removing blood stasis, the cassia bark, the Flos Lonicerae or the CAULIS LONICERAE, the coptis roots, the oriental waterplantain rhizomes and the Squama Manis have the function of promoting the flow of qi by warming the channel, the licorice roots have the function of coordinating the drug actions of a prescription, the combination of all the raw materials has the functions of enhancing the excitability of surface receptors of blood cells and platelets, stabilizing surfacial electronic charges and promoting the regulation of ion channels of cell membranes to disintegrate thrombus formed by the platelets and the blood cells, thereby, the purpose of thoroughly cure is realized. The Chinese medicinal decoction for treating thrombosis has obvious curative effect and low recurrence rate, and at present is an optimum effective medicine for treating.

Description

The Chinese herbs decoction of treatment thrombus disease

Affiliated technical field

The invention provides a kind of Chinese herbs decoction for the treatment of thrombus disease, especially the Chinese herbs decoction of property thrombosis and atrium thrombosis disease around the treatment.

Background technology

Along with the development of society, the raising of people's living standard, the sickness rate of thrombotic disease also improves year by year.At present both at home and abroad all at the research thrombolytic agent, to " four height " disease of property thrombosis (comprising lower limb depth artery and vein thrombosis) and this high incidence of atrium thrombosis, high rate of missed diagnosis, high complication, high mortality on every side, though the medicine of many such diseases of treatment is arranged, but effect is all not satisfactory, and the bigger side effect of existence, need carry out blood testing, the patient have at any time because of hemorrhage risk discontinue medication treatment, have to adopt other treatment means may.Still do not cause amputation, deformity although many patients have adopted many methods because of therapeutic effect is good even lose one's life.Doctor and patient a kind ofly need not take, can not develop complications, preferably not cause the blood coagulation factor (the VII factor, Antithrombin III etc. in the serum) significant change for a long time in expectation, need not the medicine that thrombotest detects, can effectively treat thrombus disease rapidly.

Summary of the invention

The purpose of this invention is to provide a kind ofly can address the above problem, the Chinese herbs decoction of thrombus, therapeutic effect is definite, relapse rate is low treatment thrombus disease fast.

For achieving the above object, the active component of this Chinese herbs decoction is formed by the feedstock production of following consumption proportion: Radix Ginseng 5～30g, the Radix Astragali 20～50g, Radix Angelicae Sinensis 10～30g, Rhizoma Chuanxiong 10～30g, unpeeled CORTEX MOUTAN 10～30g, Flos Carthami 10～30g, Radix Paeoniae Rubra or the Radix Paeoniae Alba 10～30g, Cortex Cinnamomi 10～30g, Flos Lonicerae or Caulis Lonicerae 20～60g, Rhizoma Coptidis or Radix Scutellariae 10～30g, Rhizoma Alismatis 10～30g, Radix Glycyrrhizae 10～30g, Squama Manis 10～30g.

For achieving the above object, the active component of this Chinese herbs decoction is prepared from by following preferable amount proportion raw material: Radix Ginseng 10～5g, the Radix Astragali 30～40g, Radix Angelicae Sinensis 15～25g, Rhizoma Chuanxiong 15～25g, unpeeled CORTEX MOUTAN 15～25g, Flos Carthami 15～25g, Radix Paeoniae Rubra or the Radix Paeoniae Alba 15～25g, Cortex Cinnamomi 15～25g, Flos Lonicerae or Caulis Lonicerae 30～50g, Rhizoma Coptidis or Radix Scutellariae 15～25g, Rhizoma Alismatis 15～25g, Radix Glycyrrhizae 15～25g, Squama Manis 15～25g.

For achieving the above object, the active component of this Chinese herbs decoction is prepared from by following optimum amount proportion raw material: Radix Ginseng 20g, Radix Astragali 35g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 20g, unpeeled CORTEX MOUTAN 20g, Flos Carthami 20g, Radix Paeoniae Rubra 20g, Cortex Cinnamomi 15～25g, Flos Lonicerae 40g, Rhizoma Coptidis 20g, Rhizoma Alismatis 20g, Radix Glycyrrhizae 20g, Squama Manis 20g.

Theory according to Chinese medicine and pharmacy " qi as the commander of blood; blood being the mother of qi; the capable then blood of gas is capable; the stagnation of QI is blood stasis then ", Radix Ginseng among the present invention, the Radix Astragali has invigorate vital energy and yang, the healthy energy internal memory, the evil function that can not do, Radix Angelicae Sinensis, Rhizoma Chuanxiong, unpeeled CORTEX MOUTAN, Flos Carthami, the Radix Paeoniae Rubra or the Radix Paeoniae Alba play the effect of activating blood circulation to dissipate blood stasis, Cortex Cinnamomi, Flos Lonicerae or Caulis Lonicerae, Rhizoma Coptidis, Rhizoma Alismatis, Squama Manis plays the effect of promoting the flow of QI in the collateral by warming the meridian, Radix Glycyrrhizae plays the function of coordinating the actions of various ingredients in a prescription, amount to and improve platelet hemocyte surface receptor irritability, surface of stability electric charge, promote the adjusting of ion channel in cell membrane to make platelet, the rapid disintegrate of thrombosis that hemocyte forms, thus reach the purpose of thorough healing.

Clinical observation research:

In recent years, this Chinese herbs decoction has carried out clinic trial on one's body 686 routine patients, male's 401 examples wherein, women's 285 examples, oldest 79 years old, 19 years old of age minimum, the diagnostic criteria that all cases are formulated according to CAIM (Chinese Association Of Integrative Medicine) peripheral vascular disease Professional Committee, the clinical manifestation statistics is as follows:

(1) venous thrombosis 410 examples, male 240 examples, women 170 examples, gastrocnemius vein position thrombosis 260 examples wherein, ilium femoral vein thrombosis 50 examples;

(2) acute arterial embolism 130 examples, male 80 examples, women 50 examples;

(3) thromboangiitis obliterans 80 examples are the male, are all the smoking patient;

(4) Takayasu arteritis 60 examples are the women;

(5) atrium thrombosis 6 examples, male 1 example, women 5 examples.

Criterion of therapeutical effect:

1, clinical cure: wound healing, deep venous thrombosis patient's edema disappears, arteries pathological changes patient arteriopalmus recovers; The colored B ultrasonic lesions showed of blood vessel vascular flow recovers more than 75%; Walk 1500 meters with no significant discomfort far away, Color Sonography shows that atrium thrombosis disappears, the person that can be engaged in the general work.

2, produce effects: wound healing, pain disappears substantially, and clinical symptoms significantly takes a turn for the better; The colored B ultrasonic lesions showed of blood vessel vascular flow 50%～75% recovers; Can be engaged in light muscle power work, abnormal sensory persons such as 1000 meters no limbs pains, swelling walk.

3, effective: wound surface dwindles, and subjective symptoms alleviates, but can not be engaged in light physical worker.

4, invalid: symptom and sign be improver not all.

The treatment way:

1, main treatment: take the present invention fry in shallow oil 1 dose of medicine juice every day, each 30～60ml, 7～10 days is a course of treatment, repeats the next course of treatment in 3～5 days at interval.General patient uses 2～3 courses of treatment and can fully recover, and severe patient is used 5 more than the course of treatment, and the person gives anti symptom treatment the gastrointestinal symptom;

2, auxiliary treatment: acra ulceration companion severe infections person, fit applications antibiotic and surgery cleaning are changed dressings; Eipathia asthenia, wound healing is slower, adds with supporting treatment once a day.

Above-mentioned part patient through 1～3 course of treatment after, its numb limbs and tense tendons, pain all have improvement in various degree, particularly the limb activity functional rehabilitation is more obvious, the observation of curative effect data are:

We have also detected Fibrinogen, the VII factor, Antithrombin III, D-Dimer levels to before and after the part patient medication simultaneously, and the result does not have significant change (P＞0.05).

The present invention can prove that through the clinical diagnosis and treatment data thrombus disease is had significant curative effect, to acute and chronic thrombosis, atrium thrombosis patient effective percentage reach 100% on every side, cure rate 95%, administration time is the shortest 6 days, no longer than 35 days, the blood coagulation factor and thrombotest detect every data all in normal range during the treatment, do not have an example to occur hemorrhagely waiting side effect and therapy discontinued has breakthrough than traditional treatment thrombotic disease medicine.

The specific embodiment

Get Radix Ginseng 15g, Radix Astragali 30g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 20g, unpeeled CORTEX MOUTAN 20g, Flos Carthami 20g, Radix Paeoniae Rubra 20g, Cortex Cinnamomi 20g, Flos Lonicerae 40g, Rhizoma Coptidis 20g, Rhizoma Alismatis 20g, Radix Glycyrrhizae 20g, Squama Manis 20g, soaked one hour, divide secondary to fry in shallow oil, water is opened and was got final product in back 6 minutes for the first time, water is opened and was got final product in back 25 minutes for the second time, fry in shallow oil altogether for twice medicine juice 120ml, ante cibum, (medicine) being taken before meal was used, every day secondary, 8 days is a course of treatment, repeats the next course of treatment in 4 days at interval, just obviously feels that two lower limbs are light behind general patient's medication couple of days, two lower limb temperature recoveries are used 2～3 courses of treatment and can be fully recovered.

Claims

1, a kind of Chinese herbs decoction for the treatment of thrombus disease, the active component that it is characterized in that it is formed by the feedstock production of following consumption proportion: Radix Ginseng 5～30g, the Radix Astragali 20～50g, Radix Angelicae Sinensis 10～30g, Rhizoma Chuanxiong 10～30g, unpeeled CORTEX MOUTAN 10～30g, Flos Carthami 10～30g, Radix Paeoniae Rubra or the Radix Paeoniae Alba 10～30g, Cortex Cinnamomi 10～30g, Flos Lonicerae or Caulis Lonicerae 20～60g, Rhizoma Coptidis or Radix Scutellariae 10～30g, Rhizoma Alismatis 10～30g, Radix Glycyrrhizae 10～30g, Squama Manis 10～30g.

2, the Chinese herbs decoction of treatment thrombus disease as claimed in claim 1, the active component that it is characterized in that it is formed by the feedstock production of following consumption proportion: Radix Ginseng 10～25g, the Radix Astragali 30～40g, Radix Angelicae Sinensis 15～25g, Rhizoma Chuanxiong 15～25g, unpeeled CORTEX MOUTAN 15～25g, Flos Carthami 15～25g, Radix Paeoniae Rubra or the Radix Paeoniae Alba 15～25g, Cortex Cinnamomi 15～25g, Flos Lonicerae or Caulis Lonicerae 30～50g, Rhizoma Coptidis or Radix Scutellariae 15～25g, Rhizoma Alismatis 15～25g, Radix Glycyrrhizae 15～25g, Squama Manis 15～25g.

3, the Chinese herbs decoction of treatment thrombus disease as claimed in claim 1, the active component that it is characterized in that it is formed by the feedstock production of following consumption proportion: Radix Ginseng 20g, Radix Astragali 35g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 20g, unpeeled CORTEX MOUTAN 20g, Flos Carthami 20g, Radix Paeoniae Rubra 20g, Cortex Cinnamomi 15～25g, Flos Lonicerae 40g, Rhizoma Coptidis 20g, Rhizoma Alismatis 20g, Radix Glycyrrhizae 20g, Squama Manis 20g.