CN107961342A - A kind of Chinese medicine composition for treating hemiplegia and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating hemiplegia and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses a kind of Chinese medicine composition for treating hemiplegia, the Chinese medicine composition includes the raw material of following parts by weight：100 150 parts of radix astragali, 5 20 parts of fructus alpiniae oxyphyllae, 10 18 parts of mantis egg-case, 5 15 parts of leech, 8 20 parts of Angelica sinensis, 9 18 parts of zaocys dhumnade, 10 20 parts of peach kernel, 12 18 parts of safflower, 25 40 parts of reticulate millettia, 6 20 parts of rhizoma Gastrodiae, 12 20 parts of ginseng.The invention also discloses a kind of preparation method for the Chinese medicine composition for treating hemiplegia.The Chinese medicine composition for the treatment of hemiplegia provided by the invention, through clinical practice application verification for many years, coordinated strengthens between each raw material, it is curative for effect in terms for the treatment of sequelae for cerebral infraction, cerebral embolism sequela and cerebral hemorrhage sequelae, have no adverse reaction, fill blood, degrading the channel, the effect of strengthening vital QI to eliminate pathogenic factors, dissolving stasis resolving sputum, can reach evident in efficacy, treat both principal and secondary aspect of disease, the effect of difficulty in relapse after healing.In addition, its preparation process is simple and easy to do, application easy to spread.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for treating hemiplegia and preparation method thereof,
More particularly, to a kind of Chinese medicine composition for treating sequelae for cerebral infraction, cerebral embolism sequela and cerebral hemorrhage sequelae and its
Preparation method.
Background technology
Hemiplegia is called hemiplegia, refers to the dyskinesia of the same side upper and lower extremities, facial muscle and lingualis lower part, is acute brain blood
The common sympton of pipe disease.Although slight hemiplegia patient still can be movable, walk and, often upper limb flexing, lower limb stretch, paralysis
Lower limb make a move draw half circle, this special walking posture, is called hemiplegic gait.Severe patient is often unable to leave the bed, and loses life
Viability.According to the degree of hemiplegia, paresis, incomplete paralysis and pamplegia can be divided into.Paresis：Show as muscular strength decrease, muscular strength
At 4-5 grades, daily life is not influenced generally, imperfection paralysis is compared with paresis weight, and scope is larger, 2-4 grades of muscular strength, pamplegia：Muscular strength 0-1
Level, paralyzed limbs are completely stiff.
Cerebrovascular disease refers to rupture of blood vessel in brain bleeding or thrombosis, caused with cerebral haemorrhage or ischemia injury disease
Shape is one group of disease of main clinical manifestation, including cerebral hemorrhage, cerebral thrombus, cerebral infarction etc., also known as cerebrovas-cularaccident or cerebral apoplexy,
It is commonly called as headstroke.The disease is common in the acute attack of crowd above middle age, and the disturbance of consciousness and quadriplegia can occur for severe patient,
It is to cause human death and disabled principal disease.
During generation acute cerebrovascular disease, because destroying corticocerebral motor area or the conduction path below it, it can all draw
Play quadriplegia and various sequelae, such as hemiplegia, facial muscle, glossolysis, facial paralysis, aphasia.Most brains go out
Blood or Changes of Patients With Cerebrovascular Diseases can all leave different degrees of hemiplegia symptom, and extreme difficulties are caused to patient's daily life.Traditional controls
Treatment method is mainly physical therapy, exercise, acupuncture, massage and massage etc., and not only the course for the treatment of is grown, and curative effect is not notable.
The content of the invention
It is an object of the invention to provide a kind of easy, safe and efficient medicine, to cure because of cerebral infarction, cerebral thrombus, brain
Various sequelae and the Chinese medicine composition of various paralysis and preparation method thereof caused by bleeding, it is existing in the prior art to solve
Problem.
To achieve the above object, the first aspect of the present invention provides a kind of Chinese medicine composition for treating hemiplegia, in described
Drug composition includes the raw material of following parts by weight：100-150 parts of radix astragali, 5-20 parts of fructus alpiniae oxyphyllae, 10-18 parts of mantis egg-case, leech
5-15 parts, 8-20 parts of Angelica sinensis, 9-18 parts of zaocys dhumnade, 10-20 parts of peach kernel, 12-18 parts of safflower, 25-40 parts of reticulate millettia, rhizoma Gastrodiae 6-20
Part, 12-20 parts of ginseng.
Further, the Chinese medicine composition includes the raw material of following parts by weight：115-130 parts of radix astragali, fructus alpiniae oxyphyllae 10-
18 parts, 10-18 parts of mantis egg-case, 8-12 parts of leech, 10-15 parts of Angelica sinensis, 12-18 parts of zaocys dhumnade, 15-20 parts of peach kernel, safflower 12-18
Part, 25-35 parts of reticulate millettia, 12-16 parts of rhizoma Gastrodiae, 12-15 parts of ginseng.
Further, the Chinese medicine composition includes the raw material of following parts by weight：120 parts of radix astragali, 15 parts of fructus alpiniae oxyphyllae, mulberry
15 parts of the egg capsule of a mantis, 10 parts of leech, 15 parts of Angelica sinensis, 15 parts of zaocys dhumnade, 15 parts of peach kernel, 15 parts of safflower, 30 parts of reticulate millettia, 15 parts of rhizoma Gastrodiae,
15 parts of ginseng.
Pharmaceutically acceptable auxiliary material, includes but not limited to disintegrant, lubricant, adhesive, diluent etc..The field of Chinese medicines
Common auxiliary material and regular dosage form can be found in such as《Pharmacy》(sixth version), People's Health Publisher.For the use of customary adjuvant
Amount, those skilled in the art can make choice according to the actual content of bulk pharmaceutical chemicals.
Further, the preparation includes any in pill, granule, tablet, capsule or oral liquid.
The second aspect of the present invention provides a kind of preparation method of the Chinese medicine composition of above-mentioned treatment hemiplegia, the method
Comprise the following steps：
1) each raw material of the corresponding parts by weight after drying is weighed；
2) each raw material is put into pot, addition water makes the water surface not have 1-2 centimetres of powder, and when immersion 1 is small, big fire is boiled, turns
Small fire stewes 1-2h slowly, and filtration, the hot water of 70-80 DEG C of addition, makes the water surface not have 1-2 centimetres of powder in filter residue, and big fire is boiled, turns
Small fire stewes 0.5-1h slowly, and filtration, merges decoction liquor twice, and relative density is the clear of 1.12-1.18 when decoction liquor is concentrated into 60 DEG C
Cream, adds pharmaceutically acceptable auxiliary material and preparation is made.
The third aspect of the present invention provides a kind of preparation method of the Chinese medicine composition of above-mentioned treatment hemiplegia, the method
For：Each raw material of the corresponding parts by weight after drying is weighed, simultaneously ground into end is mixed, is made plus pharmaceutically acceptable auxiliary material
Preparation.
Further, ground into end crosses No. 5 sieves.
The pharmacological property of Chinese medicine used in the present invention is as follows：
Radix astragali：It is sweet in flavor, slightly warm in nature.Enter spleen, lung channel.With tonifying Qi and lifting yang, strengthening exterior and reducing sweat, torr sore myogenic, profit water detumescence
Effect.For treating treatment deficiency of vital energy weak, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, ulcer is difficult to burst, burst for a long time and does not holds back,
Blood deficiency chlorosis, Heat Diabetes, chronic nephritis, albuminuria, diabetes etc..Modern medicine study shows, radix astragali containing saponin, sucrose,
The various trace elements such as polysaccharide, a variety of amino acid, folic acid and selenium, zinc, copper.There is enhancing body's immunity, liver protection, diuresis, anti-
Aging, resisting stress, decompression and wide antibacterial action.Jishengshenqiwan albuminuria can be eliminated, strengthens myocardial contractive power, is adjusted
Blood-sugar content.Radix astragali can not only coronary artery dilator, improve myocardial blood supply, improve immune function, and cell can be delayed to decline
Old process.
Fructus alpiniae oxyphyllae：Acrid flavour, it is warm-natured.Returns spleen, kidney channel.The effect of saliva being taken the photograph with warming spleen and stopping diarrha, warming up kidney contracting urine controlling nocturnal emission with astringent drugs.For controlling
Deficiency-cold in spleen and stomach is treated, is vomitted, diarrhea, crymodynia in abdomen, the more salivas of mouth, enuresis with renal asthenia, frequent micturition, seminal emission, gonorrhoea.
Mantis egg-case：It is sweet in flavor, salty, it is mild-natured.Return liver and kidney channel.With astringent sperm contracting urine, the effect of tonifying the kidney and support yang.Lost for treating
Smart involuntary emission, enuresis frequent micturition, urine gonorrhoea.
Leech：Taste is salty, bitter, mild-natured；It is poisonous.Return liver warp.With dissipating blood stasis with potent drugs, the effect of promoting menstruation Xiao Disorder.For treating blood
Stasis of blood Amenorrhea, abdominal mass lump in the abdomen, traumatic injury.
Angelica sinensis：It is sweet in flavor, pungent, it is warm-natured.Major function：Replenishing and activating blood, menstruction regulating and pain relieving, relaxes bowel.It is dizzy for blood deficiency chlorosis
Dizzy palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, dry constipation of intestines, arthralgia pain due to rheumatism, injury from falling down, ulcer sores.
Zaocys dhumnade：It is sweet in flavor, it is mild-natured.Return liver warp.Major function：Wind-dispelling, dredging collateral, stops convulsion.For rheumatoid arthritis stubborn, numbness is arrested
Contraction, apoplexy facial paralysis, hemiplegia, spasm of twitching, lockjaw, leprosy mange, scrofula malignant sore.
Peach kernel：Major function：Promoting blood circulation, relaxes bowel, relieving cough and asthma.For Amenorrhea, dysmenorrhoea , wei lump in the abdomen lump in the abdomens, fall and flutter
Damage, dry constipation of intestines.
Safflower：Acrid flavour, it is warm-natured.Converge to heart and liver channels.With invigorate blood circulation, the effect of removing blood stasis and analgesics.For treating postpartum blood
Dizzy, stasis of blood, chest impediment and cardialgia, blood product, beats the stasis of blood swell, arthralgia, paralysis due to windstroke, macular eruption being dark-purple, dysmenorrhoea, Amenorrhea.
Reticulate millettia：It is bitter, sweet, it is warm-natured.Return liver and kidney channel.With enriching blood, invigorate blood circulation, the effect of dredging collateral.For treating menstruation not
Adjust, blood deficiency chlorosis, paralysis and numbness, arthralgia pain due to rheumatism.
Rhizoma Gastrodiae：It is sweet in flavor, it is mild-natured.Returns spleen, kidney, liver, courage, the heart channel of Hang-Shaoyin.With ceases wind, the effect of arresting convulsion.For treating dizziness eye
It is black, head wind headache, extremity numbness, hemiplegia, aphasia, infantile epilepsy and convulsions.
Ginseng：Mildly bitter flavor, it is mild-natured.Returns spleen, the heart, lung channel.With tonifying Qi, tonifying spleen, beneficial lung, dredging collateral, prevent prolapse and other effects.
This prescription is suitable for hemiplegia, hemiplegia.In the traditional Chinese medical science, this syndrome is apoplexy sequelae category, and cerebrovascular disease is by rescuing
Control, after conscious, leave sequelae, such as hemiplegia, aphasia, facial paralysis, limb adynamia, disfluency, headache
Dizziness, or with brothers' edema.Sallow complexion, or it is dim it is simple and unadorned, tongue is thin white, pale tongue is purple or tongue body not just, thready and hesitant pulse is powerless etc..
The traditional Chinese medical science thinks that positive unsaturated vapor worn with age, kidney qi virtual loss, feelings will is not smooth, five excessive emotional activities, eating and drinking without temperance, and weather is dashed forward
Under the effect of the factors such as change, the imbalance of viscera function negative and positive of qi and blood, qi-movement disturbance, wind fire phlegm-blood stasis void is interlaced, horizontal to alter channels and collaterals, upper illiteracy
Clear key, the serial pathological change caused by numbness resistance brain network.Its interpretation of the cause, onset and process of an illness is in visceral dysfunction, mainly negative and positive disequilibrium, kidney
Dirty function deficiency, qi-movement disturbance phlegm-blood stasis impatency.Acute stage, is based on wind fire phlegm；Sequela stage, empty to be common with phlegm-blood stasis, sick position exists
" brain " old complaint belongs to the disease of asthenia in origin and asthenia in superficiality and simulataneous insufficiency and excessive at " kidney ", disease this in kidney deficiency.It is marked on phlegm-blood stasis.Therefore qi and activate blood circulation resolving sputum,
It is to treat this sick key that eliminating blood stasis and smoothing collaterals, which are had one's ideas straightened out,.
The invention has the advantages that：
It is provided by the invention treatment hemiplegia Chinese medicine composition, it is specific selection radix astragali, fructus alpiniae oxyphyllae, mantis egg-case, leech, when
Return, zaocys dhumnade, peach kernel, safflower, reticulate millettia, rhizoma Gastrodiae and ginseng, and be made with specific ratio, tested through clinical practice application for many years
Demonstrate,prove, coordinated strengthens between each raw material, is treated in terms for the treatment of sequelae for cerebral infraction, cerebral embolism sequela and cerebral hemorrhage sequelae
The effect of effect is definite, has no adverse reaction, fills blood, degrading the channel, strengthening vital QI to eliminate pathogenic factors, dissolving stasis resolving sputum, can reach evident in efficacy, mark
This is simultaneous to control, the effect of difficulty in relapse after healing.In addition, its preparation process is simple and easy to do, application easy to spread.
Embodiment
Following embodiments are used to illustrate the present invention, but are not limited to the scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition for treating hemiplegia, includes the raw material of following parts by weight：115 parts of radix astragali, 18 parts of fructus alpiniae oxyphyllae,
10 parts of mantis egg-case, 8 parts of leech, 20 parts of Angelica sinensis, 12 parts of zaocys dhumnade, 10 parts of peach kernel, 16 parts of safflower, 30 parts of reticulate millettia, 6 parts of rhizoma Gastrodiae,
18 parts of ginseng.
The preparation method of above-mentioned Chinese medicine composition is：
1) each raw material of the corresponding parts by weight after drying is weighed；
2) each raw material is put into pot, addition water makes the water surface not have 2 centimetres of powder, and when immersion 1 is small, big fire is boiled, turns small
Fiery 1h stewed slowly, filtration, the hot water of 70 DEG C of addition, makes the water surface not have 1 centimetre of powder, big fire is boiled, turns small fire and stewes slowly in filter residue
0.5h, filtration, merges decoction liquor twice, and relative density is 1.12 clear cream when decoction liquor is concentrated into 60 DEG C, and addition pharmaceutically may be used
Pill is made in the auxiliary material of receiving.
Embodiment 2
A kind of Chinese medicine composition for treating hemiplegia, includes the raw material of following parts by weight：150 parts of radix astragali, 10 parts of fructus alpiniae oxyphyllae,
15 parts of mantis egg-case, 5 parts of leech, 15 parts of Angelica sinensis, 18 parts of zaocys dhumnade, 12 parts of peach kernel, 15 parts of safflower, 35 parts of reticulate millettia, 12 parts of rhizoma Gastrodiae,
20 parts of ginseng.
The preparation method of above-mentioned Chinese medicine composition is：
1) each raw material of the corresponding parts by weight after drying is weighed；
2) each raw material is put into pot, addition water makes the water surface not have 1.5 centimetres of powder, and when immersion 1 is small, big fire is boiled, turns
Small fire stewes 2h slowly, and filtration, the hot water of 80 DEG C of addition, makes the water surface not have 1 centimetre of powder, big fire is boiled, and it is slow to turn small fire in filter residue
1h is stewed, filtration, merges decoction liquor twice, and relative density is 1.18 clear cream when decoction liquor is concentrated into 60 DEG C, and addition pharmaceutically may be used
Oral liquid is made in the auxiliary material of receiving.
Embodiment 3
A kind of Chinese medicine composition for treating hemiplegia, it is characterised in that the Chinese medicine composition includes following parts by weight
Raw material：It is 120 parts of radix astragali, 15 parts of fructus alpiniae oxyphyllae, 15 parts of mantis egg-case, 10 parts of leech, 15 parts of Angelica sinensis, 15 parts of zaocys dhumnade, 15 parts of peach kernel, red
Spend 15 parts, 30 parts of reticulate millettia, 15 parts of rhizoma Gastrodiae, 15 parts of ginseng.
The preparation method of above-mentioned Chinese medicine composition is：Each raw material of the corresponding parts by weight after drying is weighed, mixes simultaneously powder
End is broken into, No. 5 sieves is crossed, granule is made plus pharmaceutically acceptable auxiliary material.
Embodiment 4
A kind of Chinese medicine composition for treating hemiplegia, includes the raw material of following parts by weight：100 parts of radix astragali, 20 parts of fructus alpiniae oxyphyllae,
12 parts of mantis egg-case, 12 parts of leech, 10 parts of Angelica sinensis, 16 parts of zaocys dhumnade, 18 parts of peach kernel, 18 parts of safflower, 40 parts of reticulate millettia, rhizoma Gastrodiae 20
Part, 12 parts of ginseng.
The preparation method of above-mentioned Chinese medicine composition is：Each raw material of the corresponding parts by weight after drying is weighed, mixes simultaneously powder
End is broken into, No. 5 sieves is crossed, capsule is made plus pharmaceutically acceptable auxiliary material.
Embodiment 5
A kind of Chinese medicine composition for treating hemiplegia, includes the raw material of following parts by weight：130 parts of radix astragali, 5 parts of fructus alpiniae oxyphyllae,
18 parts of mantis egg-case, 15 parts of leech, 8 parts of Angelica sinensis, 9 parts of zaocys dhumnade, 20 parts of peach kernel, 12 parts of safflower, 25 parts of reticulate millettia, 15 parts of rhizoma Gastrodiae,
15 parts of ginseng.
The preparation method of above-mentioned Chinese medicine composition is：Each raw material of the corresponding parts by weight after drying is weighed, mixes simultaneously powder
End is broken into, No. 5 sieves is crossed, tablet is made plus pharmaceutically acceptable auxiliary material.
Test example
In order to show the Chinese medicine composition of the present invention to sequelae for cerebral infraction, cerebral embolism sequela and cerebral hemorrhage sequelae
The therapeutic effect of hemiplegia symptom, the present invention have carried out following clinical trial.
1st, patient data
The patient 526 for being diagnosed as apoplexy sequela for carrying out our hospital's treatment in the past 10 years is chosen, wherein, after cerebral infarction
Disease patient 283 is lost, cerebral embolism sequela patient 167, cerebral hemorrhage sequelae patient 76, the course of disease is 1 month to 15 years, man
Property totally 327, women be 199, the age be 45-75 Sui, average age be 58.1 years old.Symptoms include hemiplegia or hemianesthesia,
Slobbering, dispute is crooked, aphasia etc..
2nd, efficacy assessment standard
Cure：Neurological symptom and Signs disappear substantially, and the limb function of hemiplegia side recovers preferable, and life can be certainly
Reason, being capable of independent ambulation；
Improve：Neurological symptom and Signs largely disappear, and the limb function of hemiplegia side has greatly improved, and support can
Stand, can't take care of oneself, Myodynamia recovery is to 4 grades；
It is invalid：Nothing is substantially change after treatment, or symptom and Signs aggravate after treatment.
3rd, treatment method
The Chinese medicinal composition granules of the oral obtained treatment hemiplegia of the embodiment of the present invention 3, nine grams every time, three times a day,
Surrounding is as a treatment course, and curative effect is observed after 6 courses for the treatment of.
4th, result
526 patients after 6 course of therapy, wherein, in sequelae for cerebral infraction patient, cure 243 people, improve 22 people,
Invalid 18 people；In cerebral embolism sequela patient, 143 people are cured, improve 12 people, invalid 12 people；In cerebral hemorrhage sequelae patient, control
More 64 people, improve 8 people, invalid 4 people.Cure rate is up to 85.6%, and total effective rate is up to 93.5%.
Chinese medicine composition provided by the invention have dispelling, collateral-activating, removing blood stasis and promoting blood circulation the effect of, to treatment sequelae for cerebral infraction,
Hemiplegia, hemiplegia caused by cerebral embolism sequela and cerebral hemorrhage sequelae, have significant curative effect, no pair especially for salivation
Act on, treat both principal and secondary aspect of disease, positive effect.
In above-mentioned clinical test, patient is done using the blood urine routine before and after composition, hepatic and renal function, electrocardiogram etc.
Check and record details, contrast is no abnormal, it is seen that the Chinese medicine composition has no toxic side effect.Using after 1 year to above-mentioned case
Paid a return visit, no patients with recurrent.
Typical case
1st, Lee, man, 59 years old, because of dizziness, hoarseness, and it is powerless to our hospital with left limb, through CT and the traditional Chinese medical science
Inspection comprehensive diagnos is multiple cerebral infarction sequelae.Oral liquid made of oral embodiment 2, twice a day, 400 in the least every time
Rise, surrounding is as a treatment course, dizzy after a course for the treatment of, and hoarseness and the powerless symptom of suffering limb are clearly better, and continue to take 2
Patient recovers normal after the course for the treatment of.
2nd, Mr. Wang, male, 83 years old, because of dizziness headache, the upper and lower myasthenia of limbs in right side, went to a doctor, through CT and the traditional Chinese medical science for 1 week with dysfunction
Inspection comprehensive diagnos is multiple cerebral infarction sequelae.Pill (auxiliary material is honey) made of oral embodiment 1, three times a day,
Each in the morning, afternoon and evening once surrounding is as a treatment course, and after a course for the treatment of, dizziness headache and the powerless symptom of suffering limb have been alleviated；Continue to take
After two courses for the treatment of, right side upper and lower extremities muscular strength, Muscle tensility slightly weaken, and 4 grades of muscular strength, left hand held object obstacle is clearly better；Continue
Patient recovers normal after taking three courses for the treatment of.
3rd, Liu, female, 61 years old, go to a doctor when, family members generation tell its left side facial paralysis, dysphonia, right side limb activity by
Limit, pale complexion, checks that comprehensive diagnos is cerebral embolism sequela through CT and the traditional Chinese medical science.Tablet made of oral embodiment 5, daily three
Secondary, in the morning, afternoon and evening respectively once, surrounding is as a treatment course, and after three courses for the treatment of, language is slightly unfavorable, and limb function substantially recovers；Continue to take
With 5 courses for the treatment of, lamprophonia, limb function recovers normal, takes care of oneself.
4th, Yao, man, 56 years old, because post operation of hypertensive cerebral hemorrhage bleeding is dizzy, headache, left side upper and lower extremities limitation of activity, glossolalia,
Check that comprehensive diagnos is cerebral hemorrhage sequelae through CT and the traditional Chinese medical science, through carrying out my treat-and-release, take orally the granule of embodiment 3, daily
Three times, in the morning, afternoon and evening it is each once, surrounding is as a treatment course, and after two courses for the treatment of, above-mentioned symptom is clearly better, and CT examination encephaledema has disappeared
Lose.
Although above with general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to the scope of protection of present invention.
Claims (8)
1. a kind of Chinese medicine composition for treating hemiplegia, it is characterised in that the Chinese medicine composition includes the original of following parts by weight
Material：100-150 parts of radix astragali, 5-20 parts of fructus alpiniae oxyphyllae, 10-18 parts of mantis egg-case, 5-15 parts of leech, 8-20 parts of Angelica sinensis, zaocys dhumnade 9-18
Part, 10-20 parts of peach kernel, 12-18 parts of safflower, 25-40 parts of reticulate millettia, 6-20 parts of rhizoma Gastrodiae, 12-20 parts of ginseng.
2. it is according to claim 1 treatment hemiplegia Chinese medicine composition, it is characterised in that the Chinese medicine composition include with
The raw material of lower parts by weight：115-130 parts of radix astragali, 10-18 parts of fructus alpiniae oxyphyllae, 10-18 parts of mantis egg-case, 8-12 parts of leech, Angelica sinensis 10-
15 parts, 12-18 parts of zaocys dhumnade, 15-20 parts of peach kernel, 12-18 parts of safflower, 25-35 parts of reticulate millettia, 12-16 parts of rhizoma Gastrodiae, ginseng 12-
15 parts.
3. it is according to claim 1 treatment hemiplegia Chinese medicine composition, it is characterised in that the Chinese medicine composition include with
The raw material of lower parts by weight：120 parts of radix astragali, 15 parts of fructus alpiniae oxyphyllae, 15 parts of mantis egg-case, 10 parts of leech, 15 parts of Angelica sinensis, zaocys dhumnade 15
Part, 15 parts of peach kernel, 15 parts of safflower, 30 parts of reticulate millettia, 15 parts of rhizoma Gastrodiae, 15 parts of ginseng.
4. the Chinese medicine composition of the treatment hemiplegia according to any one of claim 1-3 claim, it is characterised in that institute
It is to add preparation made of pharmaceutically acceptable auxiliary material to state Chinese medicine composition.
5. it is according to claim 4 treatment hemiplegia Chinese medicine composition, it is characterised in that the preparation include pill,
It is any in granula, tablet, capsule or oral liquid.
A kind of 6. preparation method of the Chinese medicine composition of the treatment hemiplegia described in claim 1, it is characterised in that the method bag
Include following steps：
1) each raw material of the corresponding parts by weight after drying is weighed；
2) each raw material is put into pot, addition water makes the water surface not have 1-2 centimetres of powder, and when immersion 1 is small, big fire is boiled, turns small fire
Slowly stewed 1-2h, filtration, the hot water of 70-80 DEG C of addition, makes the water surface not have 1-2 centimetres of powder, big fire is boiled, turns small fire in filter residue
Slowly stewed 0.5-1h, filtration, merges decoction liquor twice, and relative density is the clear cream of 1.12-1.18 when decoction liquor is concentrated into 60 DEG C, is added
Enter pharmaceutically acceptable auxiliary material and preparation is made.
A kind of 7. preparation method of the Chinese medicine composition of the treatment hemiplegia described in claim 1, it is characterised in that the method
For：Each raw material of the corresponding parts by weight after drying is weighed, simultaneously ground into end is mixed, is made plus pharmaceutically acceptable auxiliary material
Preparation.
8. the preparation method of the Chinese medicine composition for the treatment of hemiplegia according to claim 7, it is characterised in that ground into end mistake
No. 5 sieves.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113082191A (en) * | 2021-05-12 | 2021-07-09 | 卢文刚 | Preparation for effectively treating myocardial infarction hemiplegia and preparation method thereof |
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