CN104069342A - Traditional Chinese medicine for treating acute heart failure - Google Patents

Traditional Chinese medicine for treating acute heart failure Download PDF

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Publication number
CN104069342A
CN104069342A CN201410310452.XA CN201410310452A CN104069342A CN 104069342 A CN104069342 A CN 104069342A CN 201410310452 A CN201410310452 A CN 201410310452A CN 104069342 A CN104069342 A CN 104069342A
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percent
radix
heart failure
traditional chinese
chinese medicine
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CN201410310452.XA
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李金巧
苗玉梅
马明辉
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Abstract

The invention relates to the field of traditional Chinese medicinal formula, and particularly relates to a traditional Chinese medicine for treating acute heart failure. The traditional Chinese medicine is characterized by being prepared from the following raw medicinal materials in percentage by weight: 12-16 percent of Erysimum cheiranthoides, 9-12 percent of evening primrose, 6-9 percent of root of fringed iris herb, 5-9 parts of Chinese herbaceous peony, 9-13 percent of rhodiola rosea, 6-9 percent of spina date seed, 3-6 percent of herba erigernotis, 5-7 percent of radix ceratostigmae, 5-7 percent of seville orange flower, 3-5 percent of szechwan Chinaberry fruit, 3-6 percent of henry clematis root, 3-6 percent of tropic ageratum herb, 3-6 percent of inula flower, 2-5 percent of corydalis tuber, 2-4 percent of suberect spatholobus stem and 3-5 percent of ophiopogon root, wherein the 16 raw medicinal materials are soaked in water, decocted and residue-removed to obtain filtrate. The traditional Chinese medicine has the beneficial effects of low cost, high curative effect on acute heart failure and no toxic or side effect.

Description

The Chinese medicine that is used for the treatment of acute heart failure
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine that is used for the treatment of acute heart failure.
Background technology
As everyone knows, acute heart failure (heart failure) is the most common with acute left heart failure clinically, and acute right heart failure is more rare.Acute left heart failure refers to acute attack or the myocardial contraction of the left heart function caused by abnormal that increases the weight of obviously reduces, cardiac load increases the weight of, cause that acute cardiac output rapid drawdown, pressure of pulmonary circulation raise suddenly, peripheral resistance increases, cause that pulmonary circulation is congested and occur acute pulmonary venous pleonaemia, pulmonary edema and can accompany the clinical syndrome of histoorgan hypoperfusion and cardiogenic shock.Acute right heart failure refers to that some reason sharply declines myocardium of right ventricle contractility or the front and back load of right ventricle increases the weight of suddenly, thereby causes the clinical syndrome that right cardiac output sharply lowers.Acute heart failure suddenly onset or on original chronic heart failure basis acute exacerbation, great majority show as contractility heart failure, also can show as diastolic heart failure; Premorbid patient majority is associated with organic cardiovascular disease.For the acute heart failure occurring on chronic heart failure basis, stable disease after treatment, should not be called acute heart failure again.The treatment of acute heart failure depends on the treatments such as Folium Digitalis Purpureae, diuretic, vasodilation for many years always, and because its sickness rate, mortality rate are higher, complication is many, again easily repeatedly.And common with middle-aged and elderly people, low because of its each organ function, for conventional medicine, more easily produce toleration or toxic reaction.
Summary of the invention
Object of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, and a kind of Chinese medicine that is used for the treatment of acute heart failure is provided, and cost is low, and the curative effect for the treatment of acute heart failure is high, has no side effect.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine that is used for the treatment of acute heart failure, it is characterized in that being made by the crude drug of following percentage by weight, Herba erysimi cheiranthoidis 12~16%, Radix Oenotherae erythrosepalae 9~12%, Rohdea japonica root 6~9%, Radix Paeoniae 5~9%, Radix Rhodiolae 9~13%, Semen Ziziphi Spinosae 6~9%, Herba Erigerontis 3~6%, Radix ceratostigmatis willemottiani 5~7%, CitrusaurantiumL.Var.amara Engl. 5~7%, Fructus Toosendan 3~5%, Radix Clematidis Henryi 3~6%, Herba Agerati Conyzoidis 3~6%, Flos Inulae 3~6%, Rhizoma Corydalis 2~5%, Caulis Spatholobi 2~4%, Radix Ophiopogonis 3~5%, above-mentioned 16 taste crude drug are soaked, the filtrate of removing slag after decocting to obtain.
The invention has the beneficial effects as follows, cost is low, and treatment acute heart failure curative effect is high, has no side effect.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
Adopting Herba erysimi cheiranthoidis, Radix Oenotherae erythrosepalae, Rohdea japonica root, Radix Paeoniae, Radix Rhodiolae, Semen Ziziphi Spinosae, Herba Erigerontis, Radix ceratostigmatis willemottiani, CitrusaurantiumL.Var.amara Engl., Fructus Toosendan, Radix Clematidis Henryi, Herba Agerati Conyzoidis, Flos Inulae, Rhizoma Corydalis, Caulis Spatholobi, Radix Ophiopogonis is that crude drug is prepared from.Every pair of its component (% by weight) is Herba erysimi cheiranthoidis 13.7, Radix Oenotherae erythrosepalae 10.3, Rohdea japonica root 8.2, Radix Paeoniae 8.1, Radix Rhodiolae 10.3, Semen Ziziphi Spinosae 8.2, Herba Erigerontis 4.1, Radix ceratostigmatis willemottiani 6.3, CitrusaurantiumL.Var.amara Engl. 6.2, Fructus Toosendan 4.1, Radix Clematidis Henryi 3.9, Herba Agerati Conyzoidis 4.1, Flos Inulae 3.9, Rhizoma Corydalis 3.4, Caulis Spatholobi 2.1, Radix Ophiopogonis 3.1.Getting above-mentioned 16 taste raw material gross weights is 146 grams, adds water to 900~1000ml, and water covers powder, soak 2~3 hours, effective ingredient is easy to fried, then boil with high heat again and slowly decoct about 40 minutes with slow fire, remove slag and to obtain about filtrate 150ml, medicinal residues add water 200~300ml again, decoct 15~20 minutes, and filtrate 50~70ml removes slag to obtain, be total to obtain 200~220ml left and right medicinal liquid, the Chinese medicine decoction that makes treatment acute heart failure, packs in aseptic vial, and seal bottle cap is standby.Every day potion divide 2 times oral, each (medicine) being taken before meal 100~110ml.
Herba erysimi cheiranthoidis heart tonifying of the present invention diuresis, invigorating the spleen and regulating the stomach, helps digestion.Control cardiopalmus, edema, dyspepsia; Lipid material in Radix Oenotherae erythrosepalae scalable blood, can effectively treat the diseases such as the coronary artery infraction that causes because of hypercholesterolemia, hyperlipidemia, atherosis and cerebral thrombosis, is monarch drug in side altogether; Rohdea japonica root heat-clearing and toxic substances removing, heart tonifying diuresis, relaxing muscles and tendons to promote blood circulation.Cure mainly cardiac edema, venom, traumatic injury, rheumatalgia, stomachache, traumatic hemorrhage; Radix Paeoniae has spasmolytic, the effect of easing pain, stimulate the menstrual flow.Effective to diseases such as women's stomachache, stomach spasm, dizzy, gout, diuresis, two tastes are 5 principal drug assistances mutually, are ministerial drug in side; Assistant is with Radix Rhodiolae, Semen Ziziphi Spinosae, and the kidney invigorating of Radix Rhodiolae energy, regulates the flow of vital energy and nourish blood, and cures mainly the whole body weak, uncomfortable in chest etc., also has promoting blood circulation and hemostasis, clearing away lung-heat to relieve cough, antipyretic; Semen Ziziphi Spinosae tranquilizing by nourishing the heart.The vexed uneasiness, severe palpitation, the insomnia that for heart-liver blood deficiency, cause; Herba Erigerontis has the effect of the removing toxic substances of being slightly cold, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, dredge the meridian passage, anti-inflammatory analgetic; The pain relieving of Radix ceratostigmatis willemottiani promoting flow of QI and blood.Main gastral cavity abdomen hypochondriac pain, traumatic injury, fracture; The CitrusaurantiumL.Var.amara Engl. the chest stuffiness relieving of regulating the flow of vital energy, the effect of appetizing preventing or arresting vomiting.Cure mainly breast gastral cavity painful abdominal mass vexed, anorexia, nausea and vomiting, stomachache, stomachache; The circulation of qi promoting of Fructus Toosendan soothing liver-QI, pain relieving anthelmintic, except damp and hot, clearing away liver-fire; Radix Clematidis Henryi promoting flow of QI and blood, anti-inflammation, the pain such as enemy, stomach, abdomen, muscle and joint all have analgesic effect.Also control tracheitis, furuncle swelling toxin, traumatic injury; Herba Agerati Conyzoidis expelling wind and clearing away heat, pain relieving, hemostasis, calculus.For upper respiratory tract infection, tonsillitis, pharyngolaryngitis, acute gastroenteritis, stomachache, stomachache, metrorrhagia; Flos Inulae expectorant, Hang Shui, sending down the abnormal ascending QI, preventing or arresting vomiting, softening the hard mass.Cure mainly: expectorant knot, the lower distension of the side of body, cough with asthma, singultus, saliva are as shellac varnish, epigastric oppression and rigidity, eructation unrelieved, extensive abdominal edema in the heart; Rhizoma Corydalis has promoting blood circulation to remove blood stasis, the effect of promoting the circulation of QI to relieve pain.Cure mainly headache, lumbago, colicky, bones and muscles pain, dysmenorrhea, amenorrhea, traumatic injury; Caulis Spatholobi is enriched blood, invigorates blood circulation, and dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia; Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria, altogether for making medicine in side.The ingenious prescription of 16 taste Chinese herbal medicine, science compatibility: mutual reinforcement between, the mutual-assistance can be played synergism, can improve drug effect; Mutual restraint between two drugs, the mutual-detoxication can alleviate or eliminate toxic and side effects, the mutual coordinative role of medicine, the specially good effect of playing altogether " acute heart failure ".
The embodiment that each raw material of the present invention also can the listed ratio of according to the form below (percentage by weight) mixes realizes, and its processing method is identical with embodiment mono-.
The clinical trial of carrying out below in conjunction with my institute is done further, is described in detail the present invention:
1, case selection
With reference to the diagnosis of < < acute heart failure and the 2005 > > diagnostic criterias for the treatment of guide, conformance with standard person is selected.
2, Therapeutic Method
1 dose minute every day 2 times is oral, and each (medicine) being taken before meal 100~110ml, treats two months altogether.
3, matched group adopts doctor trained in Western medicine conventional therapy: oxygen uptake, calmness, conventional therapy and the symptomatic treatments such as nitroglycerin, angiotensin-convertion enzyme inhibitor (ACEI), cardiotonic glycoside, diuretic; Treatment group is taken the embodiment of the present invention one Chinese medicine.Two groups of cases are all treated and within two months, are carried out effect judgement.
4, curative effect determinate standard
Clinical recent healing: cardiac function is corrected to 1 grade, and symptom, sign disappear substantially, and it is normal that every inspection recovers substantially;
Effective: cardiac function progress is more than 2 grades, and do not reach 1 grade of cardiac function, symptom, sign and every inspection obviously improve;
Effective: 1 grade of cardiac function progress, and do not reach 1 grade of cardiac function, symptom, sign and every inspection have to be afraid of to improve;
Invalid: cardiac function is without significant change, or increase the weight of, or dead.
5, statistical method
The all data of statistical method carry out t check and * 2 checks, and P < 0.05 has significance for difference.
6, result
Two groups of Clinical efficacy comparisons: clinical recent healing 17 examples for the treatment of group (28.33%), effective 32 examples (53.33%), effective 9 examples (15%), invalid 2 examples (3.33%), total effective rate is 96.67%; Clinical recent healing 4 examples of matched group (13.33%), effective 9 examples (30%), effective 11 examples (36.67%), invalid 6 examples (20%), total effective rate is 80%.Two groups of curative effects are Epidemiological Analysis by statistics, and difference has significant (P < 0.05), and treatment group curative effect is better than matched group.Treatment group clinical cure rate and obvious effective rate, to organizing obvious raising, have significant difference (P < 0.05).

Claims (1)

1. a Chinese medicine that is used for the treatment of acute heart failure, it is characterized in that: the crude drug by following percentage by weight is made, Herba erysimi cheiranthoidis 12~16%, Radix Oenotherae erythrosepalae 9~12%, Rohdea japonica root 6~9%, Radix Paeoniae 5~9%, Radix Rhodiolae 9~13%, Semen Ziziphi Spinosae 6~9%, Herba Erigerontis 3~6%, Radix ceratostigmatis willemottiani 5~7%, CitrusaurantiumL.Var.amara Engl. 5~7%, Fructus Toosendan 3~5%, Radix Clematidis Henryi 3~6%, Herba Agerati Conyzoidis 3~6%, Flos Inulae 3~6%, Rhizoma Corydalis 2~5%, Caulis Spatholobi 2~4%, Radix Ophiopogonis 3~5%, above-mentioned 16 taste crude drug are soaked, the filtrate of removing slag after decocting to obtain.
CN201410310452.XA 2014-06-20 2014-06-20 Traditional Chinese medicine for treating acute heart failure Pending CN104069342A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758584A (en) * 2015-03-16 2015-07-08 济南鸿飞生物技术有限公司 Medicament for treating acute heart failure and preparation method thereof
CN106860730A (en) * 2017-01-17 2017-06-20 青岛市市立医院 A kind of pharmaceutical composition for treating congestive heart failure and its application

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520680A (en) * 2013-09-29 2014-01-22 姜浩 Traditional Chinese medicine for treating acute heart failure

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520680A (en) * 2013-09-29 2014-01-22 姜浩 Traditional Chinese medicine for treating acute heart failure

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758584A (en) * 2015-03-16 2015-07-08 济南鸿飞生物技术有限公司 Medicament for treating acute heart failure and preparation method thereof
CN106860730A (en) * 2017-01-17 2017-06-20 青岛市市立医院 A kind of pharmaceutical composition for treating congestive heart failure and its application

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