CN103202903A - Traditional Chinese medicine preparation for treating skin eczema - Google Patents
Traditional Chinese medicine preparation for treating skin eczema Download PDFInfo
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- CN103202903A CN103202903A CN2013101240525A CN201310124052A CN103202903A CN 103202903 A CN103202903 A CN 103202903A CN 2013101240525 A CN2013101240525 A CN 2013101240525A CN 201310124052 A CN201310124052 A CN 201310124052A CN 103202903 A CN103202903 A CN 103202903A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating skin eczema. The external preparation is prepared from the following traditional Chinese medicine raw materials in parts by weight: 20-30 parts of vine of multiflower knotweed, 7-11 parts of folium artemisiae argyi, 10-15 parts of cortex dictamni, 10-15 parts of fructus kochiae, 8-12 parts of cicada slough, 7-11 parts of schizonepeta, 7-11 parts of radices sileris, 7-11 parts of radix sophorae flavescentis, and 7-11 parts of fructus cnidii. The traditional Chinese medicine preparation has compatibility of medicines, has the effects of dispelling cold and removing dampness, warming meridian and stopping bleeding, clearing away heat and drying dampness, dispelling wind and arresting itching, humidifying the kidney and strengthening yang, and killing parasites to relieve itching, and has a radical effect on pruritus caused by eczema.
Description
Technical field
The invention belongs to the pharmaceutical product technical field, particularly a kind of Chinese medicine preparation with natural material treatment skin eczema.
Background technology
Therefore eczematosis needs combination of inner and outside treatment clinically because mostly being endogenous, showing skin, interior clear damp and toxin, and therefore outer clear rash skin ulcer and antipruritic mostly is oral, external drug combination.When causing, allergy also need give desensitization treatment.Can consider short-term use corticosteroid to the acute universal eczema patient with multiple therapy DeGrain, remove in case namely should take the circumstances into consideration decrement after acute symptom is controlled, in case the untoward reaction that the life-time service hormone causes.There is when infection should consider to add and uses corresponding antibiotic.(1) uses therapy in.1, Chinese medicine for oral administration.Effect with clearing away heat and cooling blood, detoxifcation rash, invigorating spleen to remove dampness, enhancing autoimmunity.2, antiinflammatory, antipruritic.Commonly used have antihistaminic, a calm tranquilizer.Can select for use calcium preparation, vitamin c, thiosulfuric acid sodium intravenous to acute stage, or do the vein sealing with procaine.Can consider short-term use corticosteroid to the acute universal eczema patient with multiple therapy DeGrain, remove in case namely should take the circumstances into consideration decrement after acute symptom is controlled, in case the untoward reaction that the life-time service hormone causes.There is when infection should consider to add and uses corresponding antibiotic.(2) local treatment is selected suitable dosage form to the ill for use, and external used medicine should reach the erythra characteristics as required, selects cleaning, antipruritic, antibiotic, antiinflammatory, convergence and keratoplastics etc. for use.
General external used medicine all is based on antipruritic at present, can not play the effect of radical cure.
Summary of the invention
The object of the invention provides a kind of Chinese medicine preparation for the treatment of skin eczema, to reach eczema is played the radical cure effect.
Eczema, the traditional Chinese medical science are called " eczema of lower limb " or " dampness skin ulcer ".So-called " poison " refers to some pyretic toxicity, make health produce and repel and sensitivity response, and these pyretic toxicity may be to be caused by food, medicine or articles for daily use (as paint, camphor ball etc.)." wet " to what, refer to that physical function is subjected to wet resistance so that dull.Have seventy percent to be moisture content by the what human body, have some setbacks if the operation of water is stagnated, health just can be located the state that what " wets ", and symptom is that extremity are heavy, edema, incoordination between the spleen and stomach, stool are thin etc.Record is a lot of in the eczema one sick TCM Document, as overflows and grow a lot of the crying of water " acute eczema " all over body, and in cry " eczema of ear " of face, Zai Lei popliteal nest etc. is located is " atopic eczema " cry " scrotal eczema " at scrotum.Chronic eczema mostly is transformed by acute eczema.Acute eczema is because damp is stifling, and the visitor forms in skin, wet evaporate thermal burn and cloudy blood of a specified duration, and blood is not supported skin, so pachylosis forms chronic eczema.The cause of disease: outer because wind, wet, thermal resistance are in skin.Outer because zang-fu disharmony and liver and gall stagnated fire, spleen be wet not to be changed, disharmony of Chong and Conception Channels, blood-deficiency and wind-dry all can cause morbidity.
According to above theory and understanding, the present invention treats the Chinese medicine preparation of skin eczema, it is characterized in that adopting following weight portion raw material of Chinese medicine to make external preparation:
Caulis Polygoni Multiflori 20-30, Folium Artemisiae Argyi 7-11, Cortex Dictamni 10-15, Fructus Kochiae 10-15, Periostracum Cicadae 8-12, Herba Menthae 8-12, Herba Schizonepetae 7-11, Radix Saposhnikoviae 7-11, Radix Sophorae Flavescentis 7-11, Fructus Cnidii 7-11.
The preferential prescription of recommending of the present invention is: Caulis Polygoni Multiflori 25, Folium Artemisiae Argyi 9, Cortex Dictamni 13, the Fructus Kochiae 13, Periostracum Cicadae 10, Herba Menthae 10, Herba Schizonepetae 9, Radix Saposhnikoviae 9, Radix Sophorae Flavescentis 9, Fructus Cnidii 9.
The present invention's preparation is to make liquid behind effective ingredient ethanol or the water extraction in the raw material of Chinese medicine.
Each component effect is among the present invention:
Caulis Polygoni Multiflori: tranquilizing by nourishing the heart;
Folium Artemisiae Argyi: dispelling cold and removing dampness, warming the meridian for stopping bleeding;
Cortex Dictamni: heat clearing and damp drying, dispelling wind for relieving itching;
The Fructus Kochiae: clearing away damp-heat, diuresis, dispelling wind for relieving itching;
Periostracum Cicadae: dispelling wind and heat pathogens, rash are antipruritic, removing nebula to improve visual acuity, expelling wind to relieve convulsion;
Herba Menthae: dispelling wind and heat pathogens, refresh oneself, throat, rash are antipruritic;
Herba Schizonepetae: dispersing wind, relieving exterior syndrome, declare the hemostasis of malicious rash, dissipating blood stasis;
Radix Saposhnikoviae: dispersing wind, relieving exterior syndrome, removing dampness to relieve pain, dispelling wind for relieving itching;
Radix Sophorae Flavescentis: heat clearing and damp drying, killing parasites for relieving itching;
Fructus Cnidii: wet kidney and enhancing body, killing parasites for relieving itching.
Above-mentioned each component compatibility has dispelling cold and removing dampness, warming the meridian for stopping bleeding, heat clearing and damp drying, dispelling wind for relieving itching, wet kidney and enhancing body, killing parasites for relieving itching effect, and the pruritus that causes for eczema has the radical cure effect.
The specific embodiment
Prescription 1: Caulis Polygoni Multiflori 25 grams; Folium Artemisiae Argyi 9 grams; Cortex Dictamni 13 grams; The Fructus Kochiae 13 grams; Periostracum Cicadae 10 grams; Herba Menthae 10 grams; Herba Schizonepetae 9 grams; Radix Saposhnikoviae 9 grams; Radix Sophorae Flavescentis 9 grams; Fructus Cnidii 9 grams.
Prescription 2: Caulis Polygoni Multiflori 20, Folium Artemisiae Argyi 11, Cortex Dictamni 10, the Fructus Kochiae 15, Periostracum Cicadae 8, Herba Menthae 12, Herba Schizonepetae 7, Radix Saposhnikoviae 11, Radix Sophorae Flavescentis 7, Fructus Cnidii 11.Unit is in gram.
Prescription 3: Caulis Polygoni Multiflori 30, Folium Artemisiae Argyi 7, Cortex Dictamni 15, the Fructus Kochiae 10, Periostracum Cicadae 12, Herba Menthae 8, Herba Schizonepetae 11, Radix Saposhnikoviae 7, Radix Sophorae Flavescentis 11, Fructus Cnidii 7.Unit is in gram.
Above-mentioned prescription all will be made liquid behind effective ingredient ethanol or the water extraction in the raw material of Chinese medicine.
According to the outer preparation that is coated with of embodiment of the invention preparation, clinical report is as follows.
1 data and method
1. 1 physical data
In April, 2011～2012 year December outpatient service patient, all 134 case diagnosis meet " clinical dermatology " standard; Get rid of the heart, liver, kidney illness, diabetes and merge other skin patient.Be divided into acute eczema 43 examples, subacute eczema 38 examples, chronic eczema 53 according to the course of disease.All patients are divided into treatment group and matched group at random according to example.70 examples are organized in treatment, matched group 64 examples, when grouping to acute, subacute, chronic attention is evenly distributed (treatment group acute eczema 23 examples, subacute eczema 19 examples, chronic eczema 28 examples, matched group acute eczema 20 examples, subacute eczema 19 examples, chronic eczema 25) two groups of case sexes, age, the course of disease, the state of an illness in two groups similar.Learn to handle there was no significant difference (p〉0. 05) by statistics, have comparability.
Before the patient treatment all performance have that in various degree skin is scorching hot, pain and scratching where it itches owing to scratch or hot water is scalded and caused a lamellar erosion, oozes out, forms a scab, and spread towards periphery.
1. 2 Therapeutic Method treatment groups: adopt Chinese medicine preparation of the present invention (according to Caulis Polygoni Multiflori 25; Folium Artemisiae Argyi 9; Cortex Dictamni 13; The Fructus Kochiae 13; Periostracum Cicadae 10; Herba Menthae 10; Herba Schizonepetae 9; Radix Saposhnikoviae 9; Radix Sophorae Flavescentis 9; Fructus Cnidii 9 is made after concentrating with aqueous extract behind the unit kilogram weighing compatibility), get the present invention 50 ml and add among warm water 500 ml, 15 times is 1 course for the treatment of, each 15 min; 1 time/d.Externally coated compound Triamcinolone Acetonide frost, 2 times/d, 15d is 1 course for the treatment of.Matched group: simple externally coated compound Triamcinolone Acetonide frost, 2 times/d, 15d is 1 course for the treatment of.All should avoid suffering, peppery, drinks food during the treatment.
1. 3 criterions of therapeutical effect
Diagnose criterion of therapeutical effect with reference to the disease of tcm that State Administration of Traditional Chinese Medicine promulgated in 1994.Cure: skin lesion all disappears, clinical symptom disappearance; Effectively: skin lesion disappears more than 30 %; Invalid: skin lesion does not have obvious improvement or disappears less than 30 %.
2 results:
Treatment is organized in 70 examples, cures 52 examples, effective 11 examples, invalid 7 examples, total effective rate 90%.Wherein to all recoveries from illness of acute eczema 23 example, subacute eczema 15 example recoveries from illness, effective 4 examples, chronic eczema 14 examples of fully recovering, effective 7 examples, invalid 7 examples.
Matched group 64 examples are cured 28 examples, effective 19 examples, invalid 17 examples, total effective rate 73.4%; Wherein acute eczema is cured 21 examples, subacute eczema 7 example recoveries from illness, chronic eczema 0 example recovery from illness.
3, conclusion: the present invention to acute, the subacute eczema therapeutic effect is obviously obvious than simple kenacomb effect.
Claims (3)
1. treat the Chinese medicine preparation of skin eczema, it is characterized in that adopting following weight portion raw material of Chinese medicine to make external preparation:
Caulis Polygoni Multiflori 20-30, Folium Artemisiae Argyi 7-11, Cortex Dictamni 10-15, Fructus Kochiae 10-15, Periostracum Cicadae 8-12, Herba Menthae 8-12, Herba Schizonepetae 7-11, Radix Saposhnikoviae 7-11, Radix Sophorae Flavescentis 7-11, Fructus Cnidii 7-11.
2. the Chinese medicine preparation for the treatment of skin eczema according to claim 1 is characterized in that adopting following weight portion raw material of Chinese medicine to make external preparation:
Caulis Polygoni Multiflori 25, Folium Artemisiae Argyi 9, Cortex Dictamni 13, the Fructus Kochiae 13, Periostracum Cicadae 10, Herba Menthae 10, Herba Schizonepetae 9, Radix Saposhnikoviae 9, Radix Sophorae Flavescentis 9, Fructus Cnidii 9.
3. the Chinese medicine preparation for the treatment of skin eczema according to claim 1 and 2 is characterized in that and will make liquid behind effective ingredient ethanol or the water extraction in the raw material of Chinese medicine.
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| CN2013101240525A CN103202903A (en) | 2013-04-11 | 2013-04-11 | Traditional Chinese medicine preparation for treating skin eczema |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383087A (en) * | 2014-11-05 | 2015-03-04 | 魏磊 | Medicament for treating skin eczema |
| CN105213557A (en) * | 2015-09-30 | 2016-01-06 | 罗奕珺 | A kind of Chinese medicine composition for the treatment of eczema |
| CN105288436A (en) * | 2015-12-03 | 2016-02-03 | 刘燕燕 | Medicament for treatment of chronic eczema |
| CN105343847A (en) * | 2015-12-09 | 2016-02-24 | 广州赛莱拉生物基因工程有限公司 | Traditional Chinese medicine composition for treating eczema containing folium artemisiae argyi and preparing method thereof |
| CN105362841A (en) * | 2015-11-30 | 2016-03-02 | 刘斌 | Drug for eliminating itching |
| CN107582883A (en) * | 2017-09-19 | 2018-01-16 | 袁贯丽 | A kind of Chinese medicine for treating skin eczema itch |
| CN108904629A (en) * | 2018-09-27 | 2018-11-30 | 南通蛇类治疗研究所 | Skin eczema of scrotum itch side |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1457834A (en) * | 2003-04-12 | 2003-11-26 | 张华贵 | Detoxicating pill |
| CN1943741A (en) * | 2006-10-23 | 2007-04-11 | 王信锁 | A Chinese traditional medicinal preparation for treatment of eczema |
| CN102475813A (en) * | 2010-11-22 | 2012-05-30 | 刘宝环 | Medicament for treating eczema |
| CN102614282A (en) * | 2012-04-25 | 2012-08-01 | 董宜忠 | Medicament for treating eczema and preparation method thereof |
-
2013
- 2013-04-11 CN CN2013101240525A patent/CN103202903A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1457834A (en) * | 2003-04-12 | 2003-11-26 | 张华贵 | Detoxicating pill |
| CN1943741A (en) * | 2006-10-23 | 2007-04-11 | 王信锁 | A Chinese traditional medicinal preparation for treatment of eczema |
| CN102475813A (en) * | 2010-11-22 | 2012-05-30 | 刘宝环 | Medicament for treating eczema |
| CN102614282A (en) * | 2012-04-25 | 2012-08-01 | 董宜忠 | Medicament for treating eczema and preparation method thereof |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383087A (en) * | 2014-11-05 | 2015-03-04 | 魏磊 | Medicament for treating skin eczema |
| CN105213557A (en) * | 2015-09-30 | 2016-01-06 | 罗奕珺 | A kind of Chinese medicine composition for the treatment of eczema |
| CN105362841A (en) * | 2015-11-30 | 2016-03-02 | 刘斌 | Drug for eliminating itching |
| CN105288436A (en) * | 2015-12-03 | 2016-02-03 | 刘燕燕 | Medicament for treatment of chronic eczema |
| CN105343847A (en) * | 2015-12-09 | 2016-02-24 | 广州赛莱拉生物基因工程有限公司 | Traditional Chinese medicine composition for treating eczema containing folium artemisiae argyi and preparing method thereof |
| CN107582883A (en) * | 2017-09-19 | 2018-01-16 | 袁贯丽 | A kind of Chinese medicine for treating skin eczema itch |
| CN108904629A (en) * | 2018-09-27 | 2018-11-30 | 南通蛇类治疗研究所 | Skin eczema of scrotum itch side |
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Application publication date: 20130717 |