CN1089469A - 用于持续释放药物的传送装置的二相基材 - Google Patents

用于持续释放药物的传送装置的二相基材 Download PDF

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Publication number
CN1089469A
CN1089469A CN93118244A CN93118244A CN1089469A CN 1089469 A CN1089469 A CN 1089469A CN 93118244 A CN93118244 A CN 93118244A CN 93118244 A CN93118244 A CN 93118244A CN 1089469 A CN1089469 A CN 1089469A
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China
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base material
medicine
pharmaceutical formulation
release pharmaceutical
phase
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Pending
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CN93118244A
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English (en)
Chinese (zh)
Inventor
许宗民
陈栋奋
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Cygnus Therapeutic Systems
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Cygnus Therapeutic Systems
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Publication of CN1089469A publication Critical patent/CN1089469A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN93118244A 1992-10-05 1993-10-05 用于持续释放药物的传送装置的二相基材 Pending CN1089469A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95663592A 1992-10-05 1992-10-05
US956,635 1992-10-05
US08/056,076 US5989586A (en) 1992-10-05 1993-04-30 Two-phase matrix for sustained release drug delivery device
US056,076 1993-04-30

Publications (1)

Publication Number Publication Date
CN1089469A true CN1089469A (zh) 1994-07-20

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CN93118244A Pending CN1089469A (zh) 1992-10-05 1993-10-05 用于持续释放药物的传送装置的二相基材

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US (2) US5989586A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0662822B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH08504757A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1089469A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE198420T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU5321194A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2145631C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69329825T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0662822T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2155073T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3035626T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT662822E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW252919B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1994007468A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100457095C (zh) * 2001-05-08 2009-02-04 施瓦茨制药有限公司 用于治疗帕金森氏病的改良经皮治疗系统
CN100558350C (zh) * 2002-07-30 2009-11-11 施瓦茨制药有限公司 改良透皮递药系统
CN102172351B (zh) * 2001-05-08 2013-07-17 优时比制药有限公司 引起高罗替高汀血浆水平的用于治疗帕金森氏病的透皮治疗系统

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989586A (en) * 1992-10-05 1999-11-23 Cygnus, Inc. Two-phase matrix for sustained release drug delivery device
US5383873A (en) * 1992-12-09 1995-01-24 Regents Of The University Of Minnesota Smooth muscle chemical pacemaker
AU4761196A (en) * 1995-01-19 1996-08-07 Cygnus, Inc. Polymer adhesive formulation containing sorbent particles
US5807570A (en) * 1995-09-29 1998-09-15 Cygnus, Inc. Transdermal administration of ropinirole and analogs thereof
DE69715049T2 (de) * 1996-02-07 2003-04-03 Kissei Pharmaceutical Co., Ltd. Tranilast enthaltendes externum und verfahren zu dessen herstellung
JPH10167956A (ja) * 1996-12-11 1998-06-23 Hisamitsu Pharmaceut Co Inc セロトニン受容体拮抗薬含有経皮投与製剤
US6119036A (en) * 1997-03-26 2000-09-12 The Board Of Regents Of The University Of Oklahoma Iontophoretic transdermal delivery device
AU3170697A (en) * 1997-05-30 1998-12-30 Minnesota Mining And Manufacturing Company Transdermal drug delivery device for the delivery of tropisetron or granisetron
DE69910743T2 (de) * 1998-02-25 2004-07-08 The Government Of The United States, As Represented By The Secretary Of The Army Verwendung von hautpenetrationsförderern und für die zerstörung der oberen hautschichten geeigneten mitteln zur erhöhung der durch adp-ribosylating-exotoxin induzierten immunantwort
DE19814087A1 (de) 1998-03-30 1999-10-14 Lohmann Therapie Syst Lts Feuchtigkeitsaktivierbares therapeutisches System
DE19814084B4 (de) 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE19827732A1 (de) * 1998-06-22 1999-12-23 Rottapharm Bv Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie
ES2372592T3 (es) * 1999-04-08 2012-01-24 Intercell Usa, Inc. Formulación seca para la inmunización transcutánea.
DE19929197A1 (de) * 1999-06-25 2000-12-28 Novosis Pharma Ag Transdermalsysteme zur Abgabe von 5-HT3-Rezeptor-Antagonisten und ihre Verwendung zur antiemitischen Behandlung
US20040109874A1 (en) * 1999-11-10 2004-06-10 Powderject Vaccines, Inc. Induction of mucosal immunity by vaccination via the skin route
US6562369B2 (en) * 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of androgenic drugs hydroxide-releasing agents as permeation enhancers
US6562370B2 (en) * 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers
US6602912B2 (en) 2000-06-30 2003-08-05 Dermatrends, Inc. Transdermal administration of phenylpropanolamine
US20030104041A1 (en) * 1999-12-16 2003-06-05 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
US6562368B2 (en) 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers
US6558695B2 (en) 1999-12-16 2003-05-06 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers
US6719997B2 (en) 2000-06-30 2004-04-13 Dermatrends, Inc. Transdermal administration of pharmacologically active amines using hydroxide-releasing agents as permeation enhancers
US6586000B2 (en) * 1999-12-16 2003-07-01 Dermatrends, Inc. Hydroxide-releasing agents as skin permeation enhancers
US6673363B2 (en) * 1999-12-16 2004-01-06 Dermatrends, Inc. Transdermal and topical administration of local anesthetic agents using basic enhancers
US6565879B1 (en) 1999-12-16 2003-05-20 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers
US6582724B2 (en) 1999-12-16 2003-06-24 Dermatrends, Inc. Dual enhancer composition for topical and transdermal drug delivery
US6645520B2 (en) 1999-12-16 2003-11-11 Dermatrends, Inc. Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers
KR100393478B1 (ko) * 2000-03-29 2003-08-06 주식회사종근당 자가유화 매트릭스형 경점막·경피흡수제제
DE10015783C2 (de) * 2000-03-30 2003-12-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Abgabe von Lerisetron und seine Verwendung
US20050042194A1 (en) * 2000-05-11 2005-02-24 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
DE10027258C1 (de) * 2000-05-31 2001-10-31 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit okklusiver wirkstoffhaltiger Schicht und nicht-okklusiver Rückschicht
DE10041479A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
ATE319428T1 (de) 2000-12-07 2006-03-15 Univ Utrecht Holding Bv Zusammensetzung zur behandlung von entzündlichen erkrankungen
DE10136784A1 (de) * 2001-07-27 2003-02-20 Lohmann Therapie Syst Lts Darreichungsformen mit wirkstoffhaltigen Partikeln, zur Anwendung auf der Haut oder Schleimhaut
EP1427397B1 (en) * 2001-09-10 2008-02-13 F. Hoffmann-La Roche Ag Oily thixotropic formulations
US7273619B2 (en) * 2002-01-17 2007-09-25 Samyang Corporation Transdermal composition of an antivomiting agent
US20060263419A1 (en) * 2002-03-12 2006-11-23 Hans-Michael Wolff Transdermal therapeutic system for Parkinson's Disease
CA2489347A1 (en) * 2002-06-20 2003-12-31 Amnon Sintov Transdermal drug delivery system
EP1386605A1 (en) * 2002-07-30 2004-02-04 Schwarz Pharma Ag Improved transdermal delivery system for the administration of rotigotine
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
DE10234673B4 (de) 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US8211462B2 (en) * 2002-07-30 2012-07-03 Ucb Pharma Gmbh Hot-melt TTS for administering rotigotine
US8246980B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
PT1426049E (pt) 2002-12-02 2005-09-30 Sanol Arznei Schwarz Gmbh Administracao iontoforetica de rotigotina para o tratamento da doenca de parkinson
DE10261696A1 (de) * 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
US20050019366A1 (en) * 2002-12-31 2005-01-27 Zeldis Jerome B. Drug-coated stents and methods of use therefor
GB0302662D0 (en) 2003-02-05 2003-03-12 Strakan Ltd Transdermal granisetron
DE10334188B4 (de) 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
US20050118246A1 (en) * 2003-10-31 2005-06-02 Wong Patrick S. Dosage forms and layered deposition processes for fabricating dosage forms
EP1547592A1 (en) 2003-12-23 2005-06-29 Schwarz Pharma Ag Intranasal formulation of rotigotine
US7262145B2 (en) * 2004-04-23 2007-08-28 Kennametal Inc. Whisker-reinforced ceramic containing aluminum oxynitride and method of making the same
US20070264319A1 (en) * 2004-09-01 2007-11-15 Lebo David B Transdermal Antiemesis Delivery System, Method and Composition Therefor
SE528360C2 (sv) * 2004-09-10 2006-10-24 Doxa Ab Resorberbara keramiska kompositioner avsedda för medicinska implantat
WO2006039532A2 (en) * 2004-09-29 2006-04-13 Schwarz Pharma, Inc. Transdermal therapeutic system for parkinson’s disease
US20060263421A1 (en) * 2005-05-18 2006-11-23 Abeille Pharmaceuticals Inc Transdermal Method and Patch for Nausea
KR101207553B1 (ko) 2005-06-02 2012-12-03 (주)씨앤팜 금속 이중층 수산화물을 포함하는 생체 주사제용 약물 담체
JP2009509675A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 新規薬学的ビヒクルを用いる経皮薬剤送達システム、装置、及び方法
JP5005916B2 (ja) * 2005-12-09 2012-08-22 スリーエム イノベイティブ プロパティズ カンパニー 皮膚粘着剤用剥離剤組成物
KR101402592B1 (ko) * 2006-03-06 2014-06-17 에스케이바이오팜 주식회사 피록시캄-무기물 복합체를 포함하는 경피투여 조성물 및이를 이용한 패치시스템
WO2009086840A1 (en) 2008-01-10 2009-07-16 Coloplast A/S A pressure sensitive adhesive composition comprising a water soluble compound
EP2286814B1 (en) 2008-05-15 2013-10-16 Hisamitsu Pharmaceutical Co., Inc. Transdermal preparation containing palonosetron
DE102008060203A1 (de) 2008-12-07 2010-06-10 Dietrich Wilhelm Schacht Wirkstoffstabilisierende flächenförmige Vorrichtung
CA2746442A1 (en) * 2008-12-11 2010-06-17 A.P. Pharma, Inc. Methods for enhancing stability of polyorthoesters and their formulations
EP2281559A1 (en) 2009-06-26 2011-02-09 UCB Pharma GmbH Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis
SMT202400353T1 (it) 2009-12-22 2024-11-15 UCB Biopharma SRL Polivinilpirrolidone per la stabilizzazione di una dispersione solida della forma non cristallina della rotigotina
US8563031B2 (en) 2010-05-27 2013-10-22 Absize, Inc. Piroxicam-containing matrix patches and methods for the topical treatment of acute and chronic pain and inflammation therewith
CN102499906B (zh) * 2011-10-12 2013-04-17 长春健欣生物医药科技开发有限公司 一种罗替戈汀盐酸盐或自由碱成膜凝胶制剂及其制备方法
WO2013075822A1 (en) 2011-11-22 2013-05-30 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermal therapeutic system (tts) with rotigotine
DE102012013439A1 (de) 2012-07-03 2014-01-23 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor
DE102011119043A1 (de) 2011-11-22 2013-05-23 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System (TDS) mit Rotigotin
DE102012013421A1 (de) 2012-07-03 2014-01-09 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System (TTS) mit Rotigotin
JP2015506978A (ja) * 2012-02-08 2015-03-05 ダウ コーニング コーポレーションＤｏｗ Ｃｏｒｎｉｎｇ Ｃｏｒｐｏｒａｔｉｏｎ ヘルスケア有効成分の送達用シリコーンエマルション
WO2014198422A1 (de) 2013-06-14 2014-12-18 Tesa Labtec Gmbh Transdermales therapiesystem (tts) mit rotigotin
US20150068707A1 (en) * 2013-09-09 2015-03-12 Nec Corporation Electronic component cooling apparatus
ES2900255T3 (es) * 2017-09-04 2022-03-16 Lts Lohmann Therapie Systeme Ag Sistema de administración transdérmica que incluye un emulsionante
KR102731700B1 (ko) 2018-10-24 2024-11-15 에스케이케미칼 주식회사 비결정 로티고틴 함유 조성물 및 이의 제조 방법
PT3854388T (pt) 2020-01-24 2023-12-11 Luye Pharma Switzerland Ag Sistema terapêutico transdérmico com o princípio ativo rotigotina e pelo menos um adesivo de silicone não resistente a aminas

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4373519A (en) * 1981-06-26 1983-02-15 Minnesota Mining And Manufacturing Company Composite wound dressing
US4882352A (en) * 1986-07-28 1989-11-21 Nelson Research & Development Co. Method for treating schizophrenia
US4559222A (en) * 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
DE3333240A1 (de) * 1983-09-12 1985-03-28 Schering AG, 1000 Berlin und 4709 Bergkamen Mittel zur transdermalen applikation von arzneimittelwirkstoffen
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4885308A (en) * 1984-08-13 1989-12-05 Nelson Research & Development Co. Method and compositions for treatment of parkinsonism syndrome in mammals
US4996226A (en) * 1984-08-13 1991-02-26 Whitby Research, Inc. Method and compositions for treatment of parkinsonism syndrome in mammels
US4904247A (en) * 1984-08-31 1990-02-27 Kendall Company Pressure-sensitive hydrophilic laminate structures for use in wound dressing, transdermal and topical drug delivery
EP0186019B1 (de) * 1984-12-22 1993-10-06 Schwarz Pharma Ag Wirkstoffpflaster
US4668506A (en) * 1985-08-16 1987-05-26 Bausch & Lomb Incorporated Sustained-release formulation containing and amino acid polymer
US4713244A (en) * 1985-08-16 1987-12-15 Bausch & Lomb Incorporated Sustained-release formulation containing an amino acid polymer with a lower alkyl (C1 -C4) polar solvent
US4826686A (en) * 1985-12-14 1989-05-02 Boehringer Ingelheim Kg Therapeutic system
US4880633A (en) * 1986-03-12 1989-11-14 Merck & Co., Inc. Transdermal drug delivery system
EP0249475A3 (en) * 1986-06-13 1989-10-11 Alza Corporation Delayed percutaneous delivery
DD294867A5 (de) * 1986-07-29 1991-10-17 Gummiwerke Thueringen Gmbh Verfahren zur herstellung von latextauchartikeln mit fibrinolytischer depotwirkung
US4737410A (en) * 1986-11-28 1988-04-12 Minnesota Mining And Manufacturing Company Polyalkyloxazoline-reinforced acrylic pressure-sensitive adhesive composition
US4906463A (en) * 1986-12-22 1990-03-06 Cygnus Research Corporation Transdermal drug-delivery composition
EP0273700B1 (en) * 1986-12-25 1992-03-04 Sumitomo Electric Industries Limited Process for producing a medical vinyl chloride resin material
US4857313A (en) * 1987-05-28 1989-08-15 Warner-Lambert Company Transdermal drug delivery device comprising copolymers of N-morpholinoethyl methacrylate and 2-hydroxylmethacrylate
US4814173A (en) * 1987-09-08 1989-03-21 Warner-Lambert Company Silicone elastomer transdermal matrix system
US5035894A (en) * 1987-10-15 1991-07-30 Dow Corning Corporation Controlled release compositions and transdermal drug delivery device
US4898920A (en) * 1987-10-15 1990-02-06 Dow Corning Corporation Adhesive compositions, controlled release compositions and transdermal delivery device
US5071645A (en) * 1987-10-19 1991-12-10 Ppg Industries, Inc. Process of producing an active agent delivery device
US4959208A (en) * 1987-10-19 1990-09-25 Ppg Industries, Inc. Active agent delivery device
US5019378A (en) * 1987-12-29 1991-05-28 Cuno, Incorporated Elastomeric composition containing therapeutic agents and articles manufactured therefrom
JPH01186823A (ja) * 1988-01-21 1989-07-26 Dow Corning Kk 薬物透過性物質の製造方法
US4898734A (en) * 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
US5300291A (en) * 1988-03-04 1994-04-05 Noven Pharmaceuticals, Inc. Method and device for the release of drugs to the skin
US5118692A (en) * 1988-04-08 1992-06-02 Whitby Research, Inc. Penetration enhances for transdermal delivery of systemic agents
US5118676A (en) * 1988-04-08 1992-06-02 Whitby Research, Inc. Penetration enhancers for transdermal delivery of systemic agents
US4996199A (en) * 1988-04-08 1991-02-26 Whitby Research, Inc. Penetration enhancers for transdermal delivery of systemic agents
US5166341A (en) * 1988-07-29 1992-11-24 Dainippon Pharmaceutical Co., Ltd. 6-amino-1,4-hexahydro-1H-diazepine derivatives
NZ230068A (en) * 1988-07-29 1991-07-26 Dainippon Pharmaceutical Co Indazole-3-carboxylic acid esters and amides of diaza compounds having 6,7, or 8 ring members: preparatory processes and pharmaceutical compositions
US5240995A (en) * 1989-02-09 1993-08-31 Alza Corporation Electrotransport adhesive
DE3910543A1 (de) * 1989-04-01 1990-10-11 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US5225407A (en) * 1990-02-22 1993-07-06 Glaxo Group Limited 5-HT3 receptor antagonists for the treatment of autism
JP2849937B2 (ja) * 1990-04-18 1999-01-27 日東電工株式会社 医療用貼付剤
JP2875611B2 (ja) * 1990-08-29 1999-03-31 エーザイ株式会社 ケイ酸カルシウム含有外用剤
US5232702A (en) * 1991-07-22 1993-08-03 Dow Corning Corporation Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices
US5300299A (en) * 1991-07-22 1994-04-05 Dow Corning Corporation Silicone pressure sensitive adhesive containing alkylmethylsiloxane wax and related methods and devices
US5989586A (en) * 1992-10-05 1999-11-23 Cygnus, Inc. Two-phase matrix for sustained release drug delivery device
EP0760238B1 (en) * 1994-05-18 2002-04-17 Hisamitsu Pharmaceutical Co., Inc. Percutaneously administrable preparation for treating urination disorder

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100457095C (zh) * 2001-05-08 2009-02-04 施瓦茨制药有限公司 用于治疗帕金森氏病的改良经皮治疗系统
CN102172351B (zh) * 2001-05-08 2013-07-17 优时比制药有限公司 引起高罗替高汀血浆水平的用于治疗帕金森氏病的透皮治疗系统
CN100558350C (zh) * 2002-07-30 2009-11-11 施瓦茨制药有限公司 改良透皮递药系统

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GR3035626T3 (en) 2001-06-29
ATE198420T1 (de) 2001-01-15
DE69329825D1 (de) 2001-02-08
WO1994007468A1 (en) 1994-04-14
EP0662822B1 (en) 2001-01-03
EP0662822A4 (en) 1996-08-07
ES2155073T3 (es) 2001-05-01
US5989586A (en) 1999-11-23
AU5321194A (en) 1994-04-26
CA2145631C (en) 2004-02-10
EP0662822A1 (en) 1995-07-19
DE69329825T2 (de) 2001-06-13
JPH08504757A (ja) 1996-05-21
DK0662822T3 (da) 2001-01-29
US5840336A (en) 1998-11-24

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