CN108883033A - 含有凝胶网络相的口腔护理组合物 - Google Patents
含有凝胶网络相的口腔护理组合物 Download PDFInfo
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- CN108883033A CN108883033A CN201780021316.0A CN201780021316A CN108883033A CN 108883033 A CN108883033 A CN 108883033A CN 201780021316 A CN201780021316 A CN 201780021316A CN 108883033 A CN108883033 A CN 108883033A
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- composition
- oral care
- aliphatic amphiphile
- aliphatic
- peroxide
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- 239000000203 mixture Substances 0.000 title claims abstract description 216
- 125000001931 aliphatic group Chemical group 0.000 claims abstract description 124
- OGQYPPBGSLZBEG-UHFFFAOYSA-N dimethyl(dioctadecyl)azanium Chemical compound CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC OGQYPPBGSLZBEG-UHFFFAOYSA-N 0.000 claims abstract description 115
- 238000000227 grinding Methods 0.000 claims abstract description 32
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims abstract description 18
- 239000003795 chemical substances by application Substances 0.000 claims description 83
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 43
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 40
- 150000002978 peroxides Chemical class 0.000 claims description 32
- 229920000642 polymer Polymers 0.000 claims description 25
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 claims description 21
- 239000004094 surface-active agent Substances 0.000 claims description 21
- 150000002191 fatty alcohols Chemical class 0.000 claims description 20
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 20
- 239000000377 silicon dioxide Substances 0.000 claims description 20
- 238000000034 method Methods 0.000 claims description 19
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- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 14
- ZVVSSOQAYNYNPP-UHFFFAOYSA-N olaflur Chemical compound F.F.CCCCCCCCCCCCCCCCCCN(CCO)CCCN(CCO)CCO ZVVSSOQAYNYNPP-UHFFFAOYSA-N 0.000 claims description 12
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- NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 claims description 12
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 10
- 229960000541 cetyl alcohol Drugs 0.000 claims description 10
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims description 10
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- 239000004323 potassium nitrate Substances 0.000 claims description 10
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- 150000001875 compounds Chemical class 0.000 claims description 9
- ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 claims description 8
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- 229910052738 indium Inorganic materials 0.000 claims description 6
- APFVFJFRJDLVQX-UHFFFAOYSA-N indium atom Chemical compound [In] APFVFJFRJDLVQX-UHFFFAOYSA-N 0.000 claims description 6
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- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims description 5
- 229940047670 sodium acrylate Drugs 0.000 claims description 5
- XHZPRMZZQOIPDS-UHFFFAOYSA-N 2-Methyl-2-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid Chemical compound OS(=O)(=O)CC(C)(C)NC(=O)C=C XHZPRMZZQOIPDS-UHFFFAOYSA-N 0.000 claims description 3
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- 235000019402 calcium peroxide Nutrition 0.000 claims description 3
- DLINORNFHVEIFE-UHFFFAOYSA-N hydrogen peroxide;zinc Chemical compound [Zn].OO DLINORNFHVEIFE-UHFFFAOYSA-N 0.000 claims description 3
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- AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 claims description 3
- 229940105296 zinc peroxide Drugs 0.000 claims description 3
- PFUVRDFDKPNGAV-UHFFFAOYSA-N sodium peroxide Chemical compound [Na+].[Na+].[O-][O-] PFUVRDFDKPNGAV-UHFFFAOYSA-N 0.000 claims description 2
- RHFUXPCCELGMFC-UHFFFAOYSA-N n-(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl)-n-phenylmethoxyacetamide Chemical compound OC1C(C)(C)OC2=CC=C(C#N)C=C2C1N(C(=O)C)OCC1=CC=CC=C1 RHFUXPCCELGMFC-UHFFFAOYSA-N 0.000 claims 1
- 125000002081 peroxide group Chemical group 0.000 claims 1
- -1 poly- methylsiloxane oxygen alkane Chemical class 0.000 description 81
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- 125000000217 alkyl group Chemical group 0.000 description 19
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 16
- 239000002245 particle Substances 0.000 description 16
- 235000019640 taste Nutrition 0.000 description 16
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 15
- 150000002148 esters Chemical class 0.000 description 15
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- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 14
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- NOOLISFMXDJSKH-OPRDCNLKSA-N Isomenthol Chemical compound CC(C)[C@H]1CC[C@@H](C)C[C@H]1O NOOLISFMXDJSKH-OPRDCNLKSA-N 0.000 description 13
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- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 13
- 229920002125 Sokalan® Polymers 0.000 description 13
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- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 12
- 229920006037 cross link polymer Polymers 0.000 description 12
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- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 9
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- 125000004432 carbon atom Chemical group C* 0.000 description 8
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- 239000002562 thickening agent Substances 0.000 description 1
- 229960000790 thymol Drugs 0.000 description 1
- IUTCEZPPWBHGIX-UHFFFAOYSA-N tin(2+) Chemical compound [Sn+2] IUTCEZPPWBHGIX-UHFFFAOYSA-N 0.000 description 1
- 229910000375 tin(II) sulfate Inorganic materials 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229960003500 triclosan Drugs 0.000 description 1
- RMBMLYUFYBZPCX-XQARLGSBSA-N trifloroside Chemical compound CC(=O)OC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](CCOC3=O)[C@H]2C=C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(=O)c1cccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1O RMBMLYUFYBZPCX-XQARLGSBSA-N 0.000 description 1
- UNXRWKVEANCORM-UHFFFAOYSA-I triphosphate(5-) Chemical compound [O-]P([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O UNXRWKVEANCORM-UHFFFAOYSA-I 0.000 description 1
- PHXATPHONSXBIL-UHFFFAOYSA-N xi-gamma-Undecalactone Chemical compound CCCCCCCC1CCC(=O)O1 PHXATPHONSXBIL-UHFFFAOYSA-N 0.000 description 1
- 239000004246 zinc acetate Substances 0.000 description 1
- 239000011667 zinc carbonate Substances 0.000 description 1
- 235000004416 zinc carbonate Nutrition 0.000 description 1
- 229910000010 zinc carbonate Inorganic materials 0.000 description 1
- 229960001939 zinc chloride Drugs 0.000 description 1
- 239000011670 zinc gluconate Substances 0.000 description 1
- 235000011478 zinc gluconate Nutrition 0.000 description 1
- 229960000306 zinc gluconate Drugs 0.000 description 1
- OMSYGYSPFZQFFP-UHFFFAOYSA-J zinc pyrophosphate Chemical compound [Zn+2].[Zn+2].[O-]P([O-])(=O)OP([O-])([O-])=O OMSYGYSPFZQFFP-UHFFFAOYSA-J 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
- VRGNUPCISFMPEM-ZVGUSBNCSA-L zinc;(2r,3r)-2,3-dihydroxybutanedioate Chemical compound [Zn+2].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O VRGNUPCISFMPEM-ZVGUSBNCSA-L 0.000 description 1
- ZPEJZWGMHAKWNL-UHFFFAOYSA-L zinc;oxalate Chemical compound [Zn+2].[O-]C(=O)C([O-])=O ZPEJZWGMHAKWNL-UHFFFAOYSA-L 0.000 description 1
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- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
Priority Applications (1)
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CN202311406561.7A CN117643556A (zh) | 2016-04-01 | 2017-03-31 | 含有凝胶网络相的口腔护理组合物 |
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US201662317413P | 2016-04-01 | 2016-04-01 | |
US62/317413 | 2016-04-01 | ||
PCT/US2017/025236 WO2017173198A1 (en) | 2016-04-01 | 2017-03-31 | Oral care compositions containing a gel network phase |
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CN202311406561.7A Division CN117643556A (zh) | 2016-04-01 | 2017-03-31 | 含有凝胶网络相的口腔护理组合物 |
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CN108883033A true CN108883033A (zh) | 2018-11-23 |
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CN201780021316.0A Pending CN108883033A (zh) | 2016-04-01 | 2017-03-31 | 含有凝胶网络相的口腔护理组合物 |
CN202311406561.7A Pending CN117643556A (zh) | 2016-04-01 | 2017-03-31 | 含有凝胶网络相的口腔护理组合物 |
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CN202311406561.7A Pending CN117643556A (zh) | 2016-04-01 | 2017-03-31 | 含有凝胶网络相的口腔护理组合物 |
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US (3) | US20170281476A1 (de) |
EP (1) | EP3435959A1 (de) |
CN (2) | CN108883033A (de) |
AU (1) | AU2017240034B2 (de) |
BR (1) | BR112018069841A2 (de) |
CA (1) | CA3018555A1 (de) |
MX (1) | MX2018011989A (de) |
WO (1) | WO2017173198A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2017173198A1 (en) | 2016-04-01 | 2017-10-05 | The Procter & Gamble Company | Oral care compositions containing a gel network phase |
MX2019007358A (es) * | 2016-12-21 | 2019-09-05 | Colgate Palmolive Co | Composiciones para el cuidado bucal y metodos de uso. |
US20220265530A1 (en) * | 2021-02-19 | 2022-08-25 | The Procter & Gamble Company | Oral care compositions comprising peroxide and polymer |
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CN113301829A (zh) | 2019-02-12 | 2021-08-24 | 吉列有限责任公司 | 用于个人护理装置的瓶子 |
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2017
- 2017-03-31 WO PCT/US2017/025236 patent/WO2017173198A1/en active Application Filing
- 2017-03-31 US US15/475,170 patent/US20170281476A1/en not_active Abandoned
- 2017-03-31 CN CN201780021316.0A patent/CN108883033A/zh active Pending
- 2017-03-31 CA CA3018555A patent/CA3018555A1/en not_active Abandoned
- 2017-03-31 MX MX2018011989A patent/MX2018011989A/es unknown
- 2017-03-31 AU AU2017240034A patent/AU2017240034B2/en not_active Ceased
- 2017-03-31 EP EP17716751.7A patent/EP3435959A1/de not_active Withdrawn
- 2017-03-31 BR BR112018069841A patent/BR112018069841A2/pt not_active Application Discontinuation
- 2017-03-31 CN CN202311406561.7A patent/CN117643556A/zh active Pending
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2020
- 2020-08-24 US US17/000,393 patent/US11517509B2/en active Active
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2022
- 2022-12-05 US US18/074,838 patent/US20230104890A1/en active Pending
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US20150023890A1 (en) * | 2006-06-30 | 2015-01-22 | Colgate-Palmolive Company | High Fluoride Ion Oral Care Composition and Method for Maintaining Anticaries Activity |
CN101516323A (zh) * | 2006-09-29 | 2009-08-26 | 宝洁公司 | 包含凝胶网络的口腔组合物 |
US20130195774A1 (en) * | 2008-03-28 | 2013-08-01 | The Procter & Gamble Company | Processes Of Making Oral Compositions Containing Gel Networks |
WO2011053877A3 (en) * | 2009-10-30 | 2012-11-22 | Discus Dental, Llc | Highly stable oxidizing compositions |
CN105120960A (zh) * | 2013-04-10 | 2015-12-02 | 宝洁公司 | 包含聚有机倍半硅氧烷颗粒的口腔护理组合物 |
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MX2018011989A (es) | 2019-02-13 |
AU2017240034B2 (en) | 2020-02-06 |
US11517509B2 (en) | 2022-12-06 |
CA3018555A1 (en) | 2017-10-05 |
WO2017173198A1 (en) | 2017-10-05 |
BR112018069841A2 (pt) | 2019-01-29 |
EP3435959A1 (de) | 2019-02-06 |
AU2017240034A1 (en) | 2018-10-04 |
CN117643556A (zh) | 2024-03-05 |
US20170281476A1 (en) | 2017-10-05 |
US20200383882A1 (en) | 2020-12-10 |
US20230104890A1 (en) | 2023-04-06 |
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