CN108157953A - 一种全营养配方食品及其制备方法 - Google Patents
一种全营养配方食品及其制备方法 Download PDFInfo
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- CN108157953A CN108157953A CN201810051018.2A CN201810051018A CN108157953A CN 108157953 A CN108157953 A CN 108157953A CN 201810051018 A CN201810051018 A CN 201810051018A CN 108157953 A CN108157953 A CN 108157953A
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- Prior art keywords
- calcium
- vitamin
- addition form
- mixing
- addition
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- 235000016709 nutrition Nutrition 0.000 title claims abstract description 49
- 235000013305 food Nutrition 0.000 title claims abstract description 28
- 230000035764 nutrition Effects 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 22
- 239000011575 calcium Substances 0.000 claims abstract description 22
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 22
- 238000002156 mixing Methods 0.000 claims description 30
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 18
- 229960005069 calcium Drugs 0.000 claims description 18
- QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 16
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 16
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 13
- 239000004615 ingredient Substances 0.000 claims description 13
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 12
- 239000011777 magnesium Substances 0.000 claims description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 10
- 238000004659 sterilization and disinfection Methods 0.000 claims description 10
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 9
- 239000011772 phylloquinone Substances 0.000 claims description 9
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 8
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 8
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 8
- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Natural products N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims description 8
- 235000019152 folic acid Nutrition 0.000 claims description 8
- 229960000304 folic acid Drugs 0.000 claims description 8
- 239000011724 folic acid Substances 0.000 claims description 8
- 235000001968 nicotinic acid Nutrition 0.000 claims description 8
- 229960003512 nicotinic acid Drugs 0.000 claims description 8
- 239000011664 nicotinic acid Substances 0.000 claims description 8
- 239000011701 zinc Substances 0.000 claims description 8
- 229910052725 zinc Inorganic materials 0.000 claims description 8
- 235000016804 zinc Nutrition 0.000 claims description 8
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 7
- 102000004407 Lactalbumin Human genes 0.000 claims description 7
- 108090000942 Lactalbumin Proteins 0.000 claims description 7
- 229910052749 magnesium Inorganic materials 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 235000019796 monopotassium phosphate Nutrition 0.000 claims description 7
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims description 7
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 claims description 7
- MBWXNTAXLNYFJB-LKUDQCMESA-N phylloquinone Chemical compound C1=CC=C2C(=O)C(C/C=C(C)/CCCC(C)CCCC(C)CCCC(C)C)=C(C)C(=O)C2=C1 MBWXNTAXLNYFJB-LKUDQCMESA-N 0.000 claims description 7
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims description 6
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 6
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 6
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 claims description 6
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 6
- 235000019197 fats Nutrition 0.000 claims description 6
- 229910052748 manganese Inorganic materials 0.000 claims description 6
- 239000011572 manganese Substances 0.000 claims description 6
- 235000019192 riboflavin Nutrition 0.000 claims description 6
- 239000002151 riboflavin Substances 0.000 claims description 6
- 229960002477 riboflavin Drugs 0.000 claims description 6
- 239000011669 selenium Substances 0.000 claims description 6
- 239000011734 sodium Substances 0.000 claims description 6
- 229910052708 sodium Inorganic materials 0.000 claims description 6
- 235000012424 soybean oil Nutrition 0.000 claims description 6
- 239000003549 soybean oil Substances 0.000 claims description 6
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims description 5
- 229910021555 Chromium Chloride Inorganic materials 0.000 claims description 5
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 5
- 239000011665 D-biotin Substances 0.000 claims description 5
- 235000000638 D-biotin Nutrition 0.000 claims description 5
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 5
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 5
- 229920002472 Starch Polymers 0.000 claims description 5
- 229930003427 Vitamin E Natural products 0.000 claims description 5
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 claims description 5
- 239000001354 calcium citrate Substances 0.000 claims description 5
- 229960004256 calcium citrate Drugs 0.000 claims description 5
- 229910052804 chromium Inorganic materials 0.000 claims description 5
- 239000011651 chromium Substances 0.000 claims description 5
- QSWDMMVNRMROPK-UHFFFAOYSA-K chromium(3+) trichloride Chemical group [Cl-].[Cl-].[Cl-].[Cr+3] QSWDMMVNRMROPK-UHFFFAOYSA-K 0.000 claims description 5
- 238000005253 cladding Methods 0.000 claims description 5
- 229910052802 copper Inorganic materials 0.000 claims description 5
- 239000010949 copper Substances 0.000 claims description 5
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims description 5
- 239000011666 cyanocobalamin Substances 0.000 claims description 5
- 229960002104 cyanocobalamin Drugs 0.000 claims description 5
- 235000000639 cyanocobalamin Nutrition 0.000 claims description 5
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical group [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims description 5
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 5
- 229940099596 manganese sulfate Drugs 0.000 claims description 5
- 239000011702 manganese sulphate Substances 0.000 claims description 5
- 235000007079 manganese sulphate Nutrition 0.000 claims description 5
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 239000001508 potassium citrate Substances 0.000 claims description 5
- 229960002635 potassium citrate Drugs 0.000 claims description 5
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 claims description 5
- 235000011082 potassium citrates Nutrition 0.000 claims description 5
- 239000001230 potassium iodate Substances 0.000 claims description 5
- 235000006666 potassium iodate Nutrition 0.000 claims description 5
- JLKDVMWYMMLWTI-UHFFFAOYSA-M potassium iodate Chemical group [K+].[O-]I(=O)=O JLKDVMWYMMLWTI-UHFFFAOYSA-M 0.000 claims description 5
- 229940093930 potassium iodate Drugs 0.000 claims description 5
- 229910052711 selenium Inorganic materials 0.000 claims description 5
- 229940091258 selenium supplement Drugs 0.000 claims description 5
- 239000011780 sodium chloride Substances 0.000 claims description 5
- 239000011781 sodium selenite Substances 0.000 claims description 5
- 235000015921 sodium selenite Nutrition 0.000 claims description 5
- 229960001471 sodium selenite Drugs 0.000 claims description 5
- 239000008107 starch Substances 0.000 claims description 5
- 235000019698 starch Nutrition 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims description 5
- 235000013337 tricalcium citrate Nutrition 0.000 claims description 5
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 claims description 5
- 239000011653 vitamin D2 Substances 0.000 claims description 5
- 229940046009 vitamin E Drugs 0.000 claims description 5
- 235000019165 vitamin E Nutrition 0.000 claims description 5
- 239000011709 vitamin E Substances 0.000 claims description 5
- 239000003643 water by type Substances 0.000 claims description 5
- NAOLWIGVYRIGTP-UHFFFAOYSA-N 1,3,5-trihydroxyanthracene-9,10-dione Chemical compound C1=CC(O)=C2C(=O)C3=CC(O)=CC(O)=C3C(=O)C2=C1 NAOLWIGVYRIGTP-UHFFFAOYSA-N 0.000 claims description 4
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 4
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 4
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 4
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 4
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 claims description 4
- 229930003316 Vitamin D Natural products 0.000 claims description 4
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 4
- 235000020958 biotin Nutrition 0.000 claims description 4
- 239000011616 biotin Substances 0.000 claims description 4
- 229960002685 biotin Drugs 0.000 claims description 4
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical group [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 4
- 150000001720 carbohydrates Chemical class 0.000 claims description 4
- 235000014633 carbohydrates Nutrition 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 4
- 239000011630 iodine Substances 0.000 claims description 4
- 229910052740 iodine Inorganic materials 0.000 claims description 4
- 229910052742 iron Inorganic materials 0.000 claims description 4
- 239000011574 phosphorus Substances 0.000 claims description 4
- 229910052698 phosphorus Inorganic materials 0.000 claims description 4
- 229960003975 potassium Drugs 0.000 claims description 4
- 239000011591 potassium Substances 0.000 claims description 4
- 229910052700 potassium Inorganic materials 0.000 claims description 4
- 239000011747 thiamine hydrochloride Substances 0.000 claims description 4
- 229960000344 thiamine hydrochloride Drugs 0.000 claims description 4
- 235000019190 thiamine hydrochloride Nutrition 0.000 claims description 4
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 claims description 4
- 239000011691 vitamin B1 Substances 0.000 claims description 4
- 239000011716 vitamin B2 Substances 0.000 claims description 4
- 239000011726 vitamin B6 Substances 0.000 claims description 4
- 235000019166 vitamin D Nutrition 0.000 claims description 4
- 239000011710 vitamin D Substances 0.000 claims description 4
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 4
- 229940046008 vitamin d Drugs 0.000 claims description 4
- 239000011746 zinc citrate Substances 0.000 claims description 4
- 235000006076 zinc citrate Nutrition 0.000 claims description 4
- 229940068475 zinc citrate Drugs 0.000 claims description 4
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 3
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 3
- 239000005913 Maltodextrin Substances 0.000 claims description 3
- 229920002774 Maltodextrin Polymers 0.000 claims description 3
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 3
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 3
- 239000001506 calcium phosphate Substances 0.000 claims description 3
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 3
- 229940035034 maltodextrin Drugs 0.000 claims description 3
- 229940055726 pantothenic acid Drugs 0.000 claims description 3
- 235000019161 pantothenic acid Nutrition 0.000 claims description 3
- 239000011713 pantothenic acid Substances 0.000 claims description 3
- 229940042585 tocopherol acetate Drugs 0.000 claims description 3
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 3
- 235000019155 vitamin A Nutrition 0.000 claims description 3
- 239000011719 vitamin A Substances 0.000 claims description 3
- 229940045997 vitamin a Drugs 0.000 claims description 3
- 239000011787 zinc oxide Substances 0.000 claims description 3
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 2
- 239000001736 Calcium glycerylphosphate Substances 0.000 claims description 2
- IELOKBJPULMYRW-NJQVLOCASA-N D-alpha-Tocopheryl Acid Succinate Chemical compound OC(=O)CCC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C IELOKBJPULMYRW-NJQVLOCASA-N 0.000 claims description 2
- 239000011627 DL-alpha-tocopherol Substances 0.000 claims description 2
- 235000001815 DL-alpha-tocopherol Nutrition 0.000 claims description 2
- DKKCQDROTDCQOR-UHFFFAOYSA-L Ferrous lactate Chemical compound [Fe+2].CC(O)C([O-])=O.CC(O)C([O-])=O DKKCQDROTDCQOR-UHFFFAOYSA-L 0.000 claims description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 2
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 claims description 2
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 claims description 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 2
- CANRESZKMUPMAE-UHFFFAOYSA-L Zinc lactate Chemical compound [Zn+2].CC(O)C([O-])=O.CC(O)C([O-])=O CANRESZKMUPMAE-UHFFFAOYSA-L 0.000 claims description 2
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 claims description 2
- 235000010385 ascorbyl palmitate Nutrition 0.000 claims description 2
- 235000013734 beta-carotene Nutrition 0.000 claims description 2
- 239000011648 beta-carotene Substances 0.000 claims description 2
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 claims description 2
- 229960002747 betacarotene Drugs 0.000 claims description 2
- MDXRFOWKIZPNTA-UHFFFAOYSA-L butanedioate;iron(2+) Chemical compound [Fe+2].[O-]C(=O)CCC([O-])=O MDXRFOWKIZPNTA-UHFFFAOYSA-L 0.000 claims description 2
- VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 claims description 2
- 239000001639 calcium acetate Substances 0.000 claims description 2
- 235000011092 calcium acetate Nutrition 0.000 claims description 2
- 229960005147 calcium acetate Drugs 0.000 claims description 2
- YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 2
- 229960002713 calcium chloride Drugs 0.000 claims description 2
- 235000011148 calcium chloride Nutrition 0.000 claims description 2
- 229940062672 calcium dihydrogen phosphate Drugs 0.000 claims description 2
- 239000004227 calcium gluconate Substances 0.000 claims description 2
- 235000013927 calcium gluconate Nutrition 0.000 claims description 2
- 229960004494 calcium gluconate Drugs 0.000 claims description 2
- UHHRFSOMMCWGSO-UHFFFAOYSA-L calcium glycerophosphate Chemical compound [Ca+2].OCC(CO)OP([O-])([O-])=O UHHRFSOMMCWGSO-UHFFFAOYSA-L 0.000 claims description 2
- 229940095618 calcium glycerophosphate Drugs 0.000 claims description 2
- 235000019299 calcium glycerylphosphate Nutrition 0.000 claims description 2
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims description 2
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 claims description 2
- 239000001527 calcium lactate Substances 0.000 claims description 2
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Abstract
本发明公开了一种全营养配方食品及其制备方法,涉及药物、特医食品、保健食品技术领域。该全营养配方食品最显著的特点是价格低廉,适合于低收入或经济状况欠佳的病人,特别是长期服用的病患者用户。同时,对于糖尿病患者或糖尿病潜在患者具有一定的营养针对性,可起到预防并缓解的作用。钙元素的添加形式以有机钙为主,辅以无机钙,在保证钙元素生物利用度高的同时,又降低了产品价格。另外,本发明制备的全营养配方食品,营养搭配合理,易于消化吸收,能够作为单一营养来源满足进食受限、消化吸收障碍病人的营养需求。
Description
技术领域
本发明涉及药物、特医食品、保健食品技术领域,涉及此全营养配方食品组分的综合搭配的用途和制备方法。
技术背景
全营养配方食品是指可作为单一营养来源满足目标人群营养需求的特殊医学用途配方食品。
病人生病住院期间因忌口、进食受限、消化吸收障碍导致营养不良,仅靠日常膳食无法满足其营养需求,研究表明营养不良病人的住院时间显著长于无营养不良病人。因为营养不良可导致T淋巴细胞数目减少,降低自然杀伤细胞和IL-2的活性,减弱B细胞功能,延缓机体对致敏性抗原的反应,改变胞质的活力,从而减弱中性粒细胞对细菌的吞噬和杀伤作用,这对病人防御系统十分不利,使病人难以耐受手术、放疗或化疗对机体的影响,易引起伤口愈合不良、瘘管形成、感染等并发症的发生。据报道,患有癌症、糖尿病、肾病等疾病的病人常存在多种因素导致的营养不良,其中癌症病人营养不良发生率约为40%~80%,糖尿病患者营养不良发生率高达50%以上。改善患者营养状况,对预防感染,减少并发症,缩短住院时间,提高患者生存质量和延长生存时间有重要意义。低收入者或经济状况欠佳者因经济能力有限,在无法采用更高效的治疗手段和药物情况下,更需要充足的营养保障来应对长期的治疗或康复。而目前,尚无针对经济状况不佳的病患者的营养合理、价格优惠的全营养配方食品。
发明内容
为满足低收入者或经济状况欠佳者、进食受限、消化吸收障碍病人的营养需求,特别是长期营养需求,本发明提供了一种全营养配方食品及其制备方法。
本发明所述的一种全营养配方食品及其制备方法,其特征在于,每百克包括以下营养成分:
蛋白12.10 g~18.70 g、脂肪3.60 g~30.20 g、碳水化合物67 g~77.31 g、维生素A189.21 μg~927.60 μg、维生素D 3.36 μg~11.25 μg、维生素E 3.36 mg~33 mg、维生素K1 18.59 μg~185 μg、维生素B1 0.40 mg~4.50 mg、维生素B2 0.35 mg~3.5 mg、维生素B6 0.43mg~5.24 mg、维生素B12 0.53 μg~5.30 μg、烟酸0.89 mg~8.9 mg、叶酸93.81 μg~938 μg、泛酸2.69 mg~58.50 mg、维生素C23.01 mg~230 mg、生物素8.85 μg~88.5 μg、钠898.48 mg~1286.90 mg、钾3597.74 mg~6250 mg、铜489.20 μg~4522.6 μg、镁129.15 mg~240.46 mg、铁10.73 mg~25 mg、锌3.54 mg~15 mg、锰287.03 μg~5918.9 μg、钙575.25 mg~1500 mg、磷745.26 mg~2648.10 mg、碘47.76 mg~84.30 mg、硒30.98 μg~173.96 μg、铬75 μg~90 μg。
其中:
所述的蛋白为乳清蛋白;脂肪为大豆油;碳水化合物为羟丙基淀粉或麦芽糊精;维生素A添加形式为醋酸视黄酯、棕榈酸视黄酯、β-胡萝卜素中的一种或多种混合;维生素D添加形式为维生素D2、维生素D3中的一种或多种混合;维生素E的添加形式为D-α-生育酚、D-α-醋酸生育酚、D-α-琥珀酸生育酚、dl -α-醋酸生育酚、dl -α-生育酚、维生素E琥珀酸钙中的一种或多种混合;维生素K1添加形式为维生素K1;维生素B1添加形式为盐酸硫胺素、硝酸硫胺素中的一种或多种混合;维生素B2添加形式为核黄素、核黄素5’-磷酸钠中的一种或多种混合;维生素B6添加形式为盐酸吡哆醇;维生素B12添加形式为氰钴胺;烟酸的添加形式为烟酸、烟酰胺中的一种或多种混合;叶酸的添加形式为叶酸;泛酸的添加形式为D-泛酸钙;维生素C的添加形式为L-抗坏血酸、L-抗坏血酸钠、L-抗坏血酸钙、抗坏血酸棕榈酸酯中的一种或多种混合;生物素的添加形式为D-生物素;钠的添加形式为氯化钠;钾的添加形式为磷酸氢二钾、磷酸二氢钾、氯化钾、柠檬酸钾中的一种或多种混合;铜的添加形式为硫酸铜、葡萄糖酸铜中的一种或多种混合;镁的添加形式为碳酸镁、硫酸镁、氧化镁、氯化镁、L-苏糖酸镁中的一种或多种混合;铁的添加形式为葡萄糖酸亚铁、富马酸亚铁、硫酸亚铁、乳酸亚铁、琥珀酸亚铁中的一种或多种混合;锌的添加形式为硫酸锌、柠檬酸锌、柠檬酸锌(三水)、葡萄糖酸锌、氧化锌、乳酸锌中的一种或多种混合;锰的添加形式为硫酸锰、葡糖糖酸锰中的一种或多种混合;钙的添加形式为碳酸钙、醋酸钙、氯化钙、柠檬酸钙、葡萄糖酸钙、乳酸钙、磷酸氢钙、磷酸二氢钙、磷酸三钙(磷酸钙)、硫酸钙、L-乳酸钙、甘油磷酸钙中的一种或多种,其中以有机钙为主;磷的添加形式为磷酸二氢钾;所述的碘的添加形式为碘酸钾;硒的添加形式为亚硒酸钠、富硒酵母、L-硒-甲基硒代半胱氨酸中的一种或多种混合;所述的铬的添加形式为氯化铬。
本发明所述的全营养配方食品包括以下制备步骤:
(1)按照上述配比分别称取各营养成分;
(2)采用多步分级法充分混合各营养成分;
(3)混合后的全营养配方食品在功率为425 W~500 W、物料覆盖厚度5 mm~15 mm条件下微波杀菌100 s~120 s;
(4)杀菌后分装成50 g/包。
本发明所述的全营养食品的食用方法为:用300 ml~400ml温开水(45 ℃~60 ℃)溶解、搅拌、摇匀后,直接饮用或经管饲摄入。
本发明选用的蛋白为乳清蛋白,乳清蛋白是优质蛋白质,营养价值高,必需氨基酸种类和含量齐全,易被消化吸收,能增强免疫,脂肪、乳糖含量低,含有β-乳球蛋白、α-乳白蛋白、免疫球蛋白等多种活性成分,较动物性蛋白质中的过量饱和脂肪、胆固醇等有害物质少,能防止血脂和胆固醇升高,对心血管疾病有益。大豆油单不饱和脂肪酸含量较高,其中α-亚麻酸占7%、亚油酸占55%,满足《特殊医学用途配方食品通则》中对α-亚麻酸和亚油酸功能的要求。羟丙基淀粉是良好的助悬剂,助悬效果好,不粘壁,易分散,絮凝颗粒细腻。麦芽糊精具有良好的溶解性,可改善产品的流动性。有研究表明补充铬元素可改善糖尿病患者糖、脂代谢紊乱。本发明中钙元素的添加形式以有机钙为主辅以无机钙,在保证钙元素生物利用度高的同时,又降低了产品价格。另外,本发明所述的全营养食品采用直销的方式,直接销售给消费者,不通过医院或药店等场所或途径,从而避免了中间商赚取差价,降低了产品价格。
本发明所述的全营养配方食品价格低廉,适于低收入者长期食用,营养搭配合理,易于消化吸收,能够作为单一营养来源满足进食受限、消化吸收障碍病人的营养需求。能够改善患者营养状况,对预防感染,减少并发症,缩短住院时间,提高患者生存质量和延长生存时间有重要意义。
具体实施方式
以下通过实施例对本发明进一步说明,但这些实施例并不用于限制本发明的保护范围和适用范围。
实施例 1
实施例1的营养成分配比为:乳清蛋白14.40 g、大豆油3.60 g、羟丙基淀粉73.66 g、醋酸视黄酯189.21 μg、维生素D2 3.363 μg、D-α-生育酚3.363 mg、维生素K1 18.59 μg、盐酸硫胺素0.40 mg、核黄素0.354 mg、盐酸吡哆醇0.432 mg、氰钴胺0.531 μg、烟酸0.89 mg、叶酸93.81 μg、D-泛酸钙2.69 mg、L-抗坏血酸23.01 mg、D-生物素8.85 μg、氯化钠898.48mg、柠檬酸钾3597.32 mg、硫酸铜489.20 μg、氧化镁129.15 mg、富马酸亚铁10.73 mg、氧化锌3.54 mg、硫酸锰287.03 μg、柠檬酸钙 2876.25mg、磷酸二氢钾745.26 mg、碘酸钾47.76mg、亚硒酸钠30.98 μg、氯化铬420.51 μg。
制备步骤:
(1)按照上述配比分别称取各营养成分;
(2)采用多步分级法充分混合各营养成分;
(3)混合后的全营养配方食品在功率为425 W、物料覆盖厚度15 mm条件下微波杀菌120s;
(4)杀菌后分装成50 g/包。
食用方法:用400 ml温开水(60 ℃)溶解、搅拌、摇匀后,直接饮用或经管饲摄入。
实施例 2
实施例2的营养成分配比为:乳清蛋白12.10 g、大豆油9.25 g、羟丙基淀粉61 g、醋酸视黄酯927.60 μg、维生素D2 11.25 μg、D-α-生育酚33 mg、维生素K1 185 μg、盐酸硫胺素4.50 mg、核黄素3.50 mg、盐酸吡哆醇5.00 mg、氰钴胺5.30 μg、烟酸8.5 mg、叶酸938 μg、D-泛酸钙58.03 mg、L-抗坏血酸230 mg、D-生物素88.5 μg、氯化钠1286.44 mg、柠檬酸钾6250 mg、硫酸铜4522.6 μg、氧化镁240.46 mg、富马酸亚铁25 mg、氧化锌15 mg、硫酸锰5918.9 μg、柠檬酸钙7500 mg、磷酸二氢钾2648.10 mg、碘酸钾84.30 mg、亚硒酸钠173.96μg、氯化铬461.54 μg。
制备步骤:
(1)按照上述配比分别称取各营养成分;
(2)采用多步分级法充分混合各营养成分;
(3)混合后的全营养配方食品在功率为500 W、物料覆盖厚度15 mm条件下微波杀菌100s;
(4)杀菌后分装成50 g/包。
食用方法:用300 ml温开水(45 ℃)溶解、搅拌、摇匀后,直接饮用或经管饲摄入。
实施例 3
实施例3的营养成分配比为:乳清蛋白18.70 g、大豆油4.84 g、麦芽糊精67.70 g、醋酸视黄酯625.31 μg、维生素D2 7.65 μg、D-α-生育酚15.32 mg、维生素K1 80.26 μg、盐酸硫胺素2.36 mg、核黄素1.75 mg、盐酸吡哆醇2.63 mg、氰钴胺2.54 μg、烟酸4.53 mg、叶酸486.30 μg、D-泛酸钙29.63 mg、L-抗坏血酸126.30 mg、D-生物素43.62 μg、氯化钠898.48mg、柠檬酸钾3757.36 mg、硫酸铜2698.30 μg、氧化镁229.15 mg、富马酸亚铁10.73 mg、氧化锌3.54 mg、硫酸锰3650.3 μg、柠檬酸钙2876.25mg、磷酸二氢钾745.26 mg、碘酸钾47.76mg、亚硒酸钠89.63 μg、氯化铬384.62 μg。
制备步骤:
(1)按照上述配比分别称取各营养成分;
(2)采用多步分级法充分混合各营养成分;
(3)混合后的全营养配方食品在功率为425 W、物料覆盖厚度5 mm条件下微波杀菌110s;
(4)杀菌后分装成50 g/包。
食用方法:用350 ml温开水(50 ℃)溶解、搅拌、摇匀后,直接饮用或经管饲摄入。
Claims (7)
1.一种全营养配方食品及其制备方法,其特征在于每百克中包括以下营养成分:蛋白12.10 g~18.70 g、脂肪3.60 g~30.20 g、碳水化合物67 g~77.31 g、维生素A 189.21 μg~927.60 μg、维生素D 3.36 μg~11.25 μg、维生素E 3.36 mg~33 mg、维生素K1 18.59 μg~185μg、维生素B10.40 mg~4.50 mg、维生素B2 0.35 mg~3.5 mg、维生素B6 0.43 mg~5.24 mg、维生素B12 0.53 μg~5.30 μg、烟酸0.89 mg~8.9 mg、叶酸93.81 μg~938 μg、泛酸2.69 mg~58.50 mg、维生素C 23.01 mg~230 mg、生物素8.85 μg~88.5 μg、钠898.48 mg~1286.90mg、钾3597.74 mg~6250 mg、铜489.20 μg~4522.6 μg、镁129.15 mg~240.46 mg、铁10.73mg~25 mg、锌3.54 mg~15 mg、锰287.03 μg~5918.9 μg、钙575.25 mg~1500 mg、磷745.26mg~2648.10 mg、碘47.76 mg~84.30 mg、硒30.98 μg~173.96 μg、铬75 μg~90 μg。
2.如权利要求1所述的一种全营养配方食品,其制备方法为:将权利要求1所述的各营养成分按比例充分混匀→微波杀菌→分装成50 g/包。
3.如权利要求2所述的一种全营养配方食品的制备方法,其特征是所述的混匀方法为多步分级混匀。
4.如权利要求2所述的一种全营养配方食品的制备方法,其特征是所述的微波杀菌功率为425 W~500 W、时间100 s~120 s、物料覆盖厚度为5 mm~15 mm。
5.如权利要求1所述的一种全营养配方食品,其特征在于食用方法为,50 g每包用300ml~400 ml温开水(45 ℃~60 ℃)溶解、搅拌、摇匀后,直接饮用或经管饲摄入。
6.如权利要求1所述的一种全营养配方食品及其制备方法,其特征在于:所述的蛋白为乳清蛋白;所述的脂肪为大豆油;所述的碳水化合物为羟丙基淀粉或麦芽糊精;所述的维生素A添加形式为醋酸视黄酯、棕榈酸视黄酯、β-胡萝卜素中的一种或多种混合;所述的维生素D添加形式为维生素D2、维生素D3中的一种或多种混合;所述的维生素E的添加形式为D-α-生育酚、D-α-醋酸生育酚、D-α-琥珀酸生育酚、dl -α-醋酸生育酚、dl -α-生育酚、维生素E琥珀酸钙中的一种或多种混合;所述的维生素K1添加形式为维生素K1;所述的维生素B1添加形式为盐酸硫胺素、硝酸硫胺素中的一种或多种混合;所述的维生素B2添加形式为核黄素、核黄素5’-磷酸钠中的一种或多种混合;所述的维生素B6添加形式为盐酸吡哆醇;所述的维生素B12添加形式为氰钴胺;所述的烟酸的添加形式为烟酸、烟酰胺中的一种或多种混合;所述的叶酸的添加形式为叶酸;所述的泛酸的添加形式为D-泛酸钙;所述的维生素C的添加形式为L-抗坏血酸、L-抗坏血酸钠、L-抗坏血酸钙、抗坏血酸棕榈酸酯中的一种或多种混合;所述的生物素的添加形式为D-生物素;所述的钠的添加形式为氯化钠;所述的钾的添加形式为磷酸氢二钾、磷酸二氢钾、氯化钾、柠檬酸钾中的一种或多种混合;所述的铜的添加形式为硫酸铜、葡萄糖酸铜中的一种或多种混合;所述的镁的添加形式为碳酸镁、硫酸镁、氧化镁、氯化镁、L-苏糖酸镁中的一种或多种混合;所述的铁的添加形式为葡萄糖酸亚铁、富马酸亚铁、硫酸亚铁、乳酸亚铁、琥珀酸亚铁中的一种或多种混合;所述的锌的添加形式为硫酸锌、柠檬酸锌、柠檬酸锌(三水)、葡萄糖酸锌、氧化锌、乳酸锌中的一种或多种混合;所述的锰的添加形式为硫酸锰、葡糖糖酸锰中的一种或多种混合;所述的钙的添加形式为碳酸钙、醋酸钙、氯化钙、柠檬酸钙、葡萄糖酸钙、乳酸钙、磷酸氢钙、磷酸二氢钙、磷酸三钙(磷酸钙)、硫酸钙、L-乳酸钙、甘油磷酸钙中的一种或多种,其中以有机钙为主;所述的磷的添加形式为磷酸二氢钾;所述的碘的添加形式为碘酸钾;所述的硒的添加形式为亚硒酸钠、富硒酵母、L-硒-甲基硒代半胱氨酸中的一种或多种混合;所述的铬的添加形式为氯化铬。
7.如权利要求1所述的一种全营养配方食品,其特征在于销售方式为直接销售给消费者,不通过医院、超市或药店等场所或途径,减少中间环节,降低费用,实现低价薄利销售的特点,消费者可以更经济、更实惠的食用,满足本产品有利于长期食用的效果。
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