CN107648329A - A kind of hairyvein agrimony is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology - Google Patents
A kind of hairyvein agrimony is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology Download PDFInfo
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- CN107648329A CN107648329A CN201610582776.8A CN201610582776A CN107648329A CN 107648329 A CN107648329 A CN 107648329A CN 201610582776 A CN201610582776 A CN 201610582776A CN 107648329 A CN107648329 A CN 107648329A
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- Prior art keywords
- hairyvein agrimony
- fresh
- dried
- preparation technology
- decoction pieces
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of fresh squeeze of hairyvein agrimony to be dried in vacuo powder decoction pieces and its preparation technology.The technique is cleaned, eluted, segment after the harvesting of hairyvein agrimony medicinal material, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is dried in vacuo, is vacuum-packed after crushing.Hairyvein Agrimonia Herd medicine materical crude slice prepared by this method, remains the polarity in medicinal material and nonpolar active ingredient to greatest extent.Medicine materical crude slice is beneficial to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.
Description
Technical field
The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese medicine hairyvein agrimony medicine materical crude slice.
Background technology
Chinese medicine hairyvein agrimony is rosaceous plant hairyvein agrimonyAgrimonia pilosaLedeb. dry aerial parts.This
Product have astringing to arrest bleeding, preventing malaria, stop dysentery, removing toxic substances and other effects, the treatment for hemoptysis, haematemesis, dysentery etc..
The processing mode of common hairyvein agrimony medicine materical crude slice is：Medicinal material harvests, and removes impurity, segment, dries, then accumulating of packing.
Such prepared herbal medicine in small pieces ready for decoction, bulky, Hygienic Index is poor, easily pollutes and goes mouldy, quality it is difficult to ensure that, be unfavorable for formula adjust
With ensure its clinical efficacy, or even the harm of recessiveness is brought to patient.
At present, in the market also has the manufactured granule pieces sale after extraction of hairyvein agrimony medicinal material.The preparation of granule pieces
Process, extraction not only time consumption and energy consumption, and do solvent because commonly using substantial amounts of water, the nonpolar active ingredient in medicinal material is difficult to be carried
Take out.Further, since the hairyvein agrimony medicinal material of extraction is also to dry and by storage for a long time, therefore, active ingredient
Loss is also very big.In order to ensure hairyvein agrimony medicinal material clinic effectively, steady quality, a kind of new hairyvein agrimony medicine materical crude slice and its
Preparation technology urgently develops.
The content of the invention
The invention discloses " a kind of hairyvein agrimony is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology ".This technique can be with
Retain polarity and the nonpolar active ingredient in hairyvein agrimony medicinal material while to greatest extent, avoid medicinal material from being processed in existing medicine materical crude slice
With the decline of the loss of caused active ingredient and medical material quanlity in storage and transport process, pollution of the medicinal material by mould etc. is reduced, to true
The steady quality and clinical safety for protecting hairyvein agrimony medicine materical crude slice effectively have great importance.
To achieve these goals, the technical scheme is that：
Its herb is gathered in hairyvein agrimony picking time, is cleaned, after washing, takes advantage of fresh squeezing.In the dregs of a decoction after squeezing, 1 ~ 5 times of amount is added
Water, stir 5 ~ 30min, take juice with plate and frame filter press press filtration.The remaining dregs of a decoction press extracting juice again.Merge concoction three times, with 40 ~
120 mesh screens, obtain hairyvein agrimony concoction.Obtained hairyvein agrimony concoction is concentrated under reduced pressure into relative density under the conditions of 40 ~ 75 DEG C
For 1.05 ~ 1.30 medicinal extract, and it be crushed into 60 ~ 120 mesh sieves after 4 ~ 8 hours in 40 ~ 70 DEG C of vacuum drying, is vacuum-packed,
Produce fresh squeeze of hairyvein agrimony and be dried in vacuo powder decoction pieces.
On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, medicine materical crude slice manufacturer, the date of manufacture,
The information such as Contents of Main Components, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Hairyvein agrimony is enclosed in bag
Thin layer differentiate collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product,
Quick Response Code is printed on, can be linked by scanning and obtain the former plant photo of product, medicinal material photo, medicine materical crude slice photo, character and micro-
The information such as diagnostic characteristics.
The present invention is advantageous in that：
The hairyvein agrimony medicinal material of fresh collection, clean and directly squeezed after washing, filter, be concentrated under reduced pressure, being dried in vacuo, resulting powder
Last medicine materical crude slice, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume compared to traditional medicine materical crude slice volume significantly
Ground reduces, vacuum packaging so that prepared slice quality is more stable, is adjusted beneficial to accumulating and clinic, and there is very significant society to anticipate
Justice and economic implications.
Embodiment
Embodiment 1
By the hairyvein agrimony medicinal material of fresh collection, clean, silt is washed with water, take advantage of using fresh herb squeezer pressure extracting juice.The gained dregs of a decoction add 3
The drinking water of amount again, stir 20min, plate and frame filter press pressure extracting juice.The remaining dregs of a decoction press extracting juice with squeezer again.Will be above-mentioned
3 times concoction merges, with 100 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 65 DEG C.It is relatively close in medicinal extract obtained by concentration
Spend for 1.15 when, be transferred in vacuum drying chamber, in 60 DEG C dry 8 hours, after crushing cross 60 mesh sieves, pack, 1kg/ bags, add
Packed antioxidant and drier, Vacuum Package.
Embodiment 2
By the hairyvein agrimony medicinal material of fresh collection, clean, silt is washed with water, take advantage of using fresh herb squeezer pressure extracting juice.The gained dregs of a decoction add 5
The drinking water of amount again, stir 30min, plate and frame filter press pressure extracting juice.The remaining dregs of a decoction press extracting juice with squeezer again.Will be above-mentioned
3 times concoction merges, with 80 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 70 DEG C.In medicinal extract relative density obtained by concentration
For 1.10 when, be transferred in vacuum drying chamber, in 65 DEG C dry 6 hours, after crushing cross 60 mesh sieves, pack, 1kg/ bags, add bag
Fill antioxidant and drier, Vacuum Package.
Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention
It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected
Within the scope of.
Claims (2)
1. a kind of hairyvein agrimony is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology, it is characterised in that：Adopted in hairyvein agrimony picking time
Collect its aerial part, clean, 1 ~ 10cm section is cut into after washing, and take advantage of fresh squeezing, the water of the dregs of a decoction 1 ~ 5 times of amount of addition, stirring 5 ~
30min, plate and frame filter press press filtration take juice, and the remaining dregs of a decoction press extracting juice again, merge concoction three times, 40 ~ 120 mesh screens, obtain celestial
Crane herbal medicine juice.
2. the fresh squeezing of a kind of hairyvein agrimony according to claim 1 is dried in vacuo powder decoction pieces and its preparation technology, its feature exist
In：Obtained hairyvein agrimony concoction is concentrated under reduced pressure into the medicinal extract that relative density is 1.05 ~ 1.30 under the conditions of 40 ~ 75 DEG C, and will
It crushed 60 ~ 120 mesh sieves after being dried in vacuo 4 ~ 8 hours in 40 ~ 70 DEG C, be vacuum-packed, and produces fresh squeeze of hairyvein agrimony and is dried in vacuo
Powder decoction pieces.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610582776.8A CN107648329A (en) | 2016-07-23 | 2016-07-23 | A kind of hairyvein agrimony is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610582776.8A CN107648329A (en) | 2016-07-23 | 2016-07-23 | A kind of hairyvein agrimony is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107648329A true CN107648329A (en) | 2018-02-02 |
Family
ID=61126365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610582776.8A Pending CN107648329A (en) | 2016-07-23 | 2016-07-23 | A kind of hairyvein agrimony is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology |
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| CN (1) | CN107648329A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105193894A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying cholla stem powdery decoction pieces and preparation process thereof |
| CN105194009A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying spreading hedyotis herb powdery decoction pieces and preparation process thereof |
| CN105213445A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Portulacae fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105213451A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Taraxaci fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105213740A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Aloe fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105287861A (en) * | 2015-11-22 | 2016-02-03 | 徐漫 | Freshly-squeezed paulownia flower vacuum-dried powdery decoction piece and preparation technology thereof |
-
2016
- 2016-07-23 CN CN201610582776.8A patent/CN107648329A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105193894A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying cholla stem powdery decoction pieces and preparation process thereof |
| CN105194009A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying spreading hedyotis herb powdery decoction pieces and preparation process thereof |
| CN105213445A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Portulacae fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105213451A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Taraxaci fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105213740A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Aloe fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105287861A (en) * | 2015-11-22 | 2016-02-03 | 徐漫 | Freshly-squeezed paulownia flower vacuum-dried powdery decoction piece and preparation technology thereof |
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180202 |
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| WD01 | Invention patent application deemed withdrawn after publication |