CN105998131A

CN105998131A - Chinese lobelia freshly-squeezed spray drying powder decoction tablets and preparation process thereof

Info

Publication number: CN105998131A
Application number: CN201610582758.XA
Authority: CN
Inventors: 徐漫
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-07-23
Filing date: 2016-07-23
Publication date: 2016-10-12

Abstract

The invention discloses Chinese lobelia freshly-squeezed spray drying powder decoction tablets and a preparation process thereof. The preparation process includes: after picking Chinese lobelia, selecting, drip-washing, freshly squeezing, and filtering to obtain medicine juice; adding water into medicine residue, stirring, filtering, and squeezing; mixing the medicine juice; depressurizing for concentrating, spray drying, collecting a spray drying product, smashing, and vacuum packaging. Polar and nonpolar active ingredients in the Chinese lobelia powder decoction tablets prepared by the process are retained to the greatest extent. The decoction tablets are conducive to storage and transport, convenient to compound, controllable in quality and reliable in treatment effect and are of important significance in guaranteeing clinical treatment effect of traditional Chinese medicine. The preparation process has remarkable social benefit and economic benefit in popularization and implementation.

Description

A kind of Herba Lobeliae Chinensis fresh squeezing spray-dried powders decoction pieces and preparation technology thereof

Technical field

The invention belongs to Chinese crude drug manufacture field, particularly relate to the processing technique of Chinese medicine Herba Lobeliae Chinensis decoction pieces.

Background technology

Chinese medicine Herba Lobeliae Chinensis is Campanulaceae Herba Lobeliae ChinensisLobelia chinensis Lour. dry herb.This product has There are the effects such as inducing diuresis to remove edema, heat-clearing and toxic substances removing, can be used for treating extensive abdominal edema, face foot edema, carbuncle furuncle, snake bite and insect sting etc..

The processing mode of common Herba Lobeliae Chinensis decoction pieces is: summer gathers, and removes silt, cleans, dries, then accumulating of packing. This type of prepared herbal medicine in small pieces ready for decoction, bulky, Hygienic Index is poor, easily pollutes and goes mouldy, quality it is difficult to ensure that, be unfavorable for that formula is adjusted With guarantee its clinical efficacy, even to patient bring recessiveness harm.

At present, granule pieces market also having Herba Lobeliae Chinensis medical material to make after extracting is sold.The preparation of granule pieces Process, extracts not only time consumption and energy consumption, and because conventional substantial amounts of water does solvent, the nonpolar effective ingredient in medical material is difficult to be carried Take out.Additionally, due to the Herba Lobeliae Chinensis medical material extracted also is to be dried and through long-time storage, therefore, effective ingredient Loss is also the biggest.In order to ensure Herba Lobeliae Chinensis medical material clinical effectively, steady quality, a kind of novel Herba Lobeliae Chinensis decoction pieces and Preparation technology urgently develops.

Summary of the invention

The invention discloses " a kind of Herba Lobeliae Chinensis fresh squeezing spray-dried powders decoction pieces and preparation technology thereof ".This technique is permissible The polarity in Herba Lobeliae Chinensis medical material and nonpolar effective ingredient is retained, it is to avoid medical material is processed at existing decoction pieces while to greatest extent With loss and the decline of medical material quanlity of the effective ingredient caused in storage and transport process, reduce the medical material pollution by mycete etc., to really Steady quality and the clinical safety of protecting Herba Lobeliae Chinensis decoction pieces effectively have great importance.

To achieve these goals, the technical scheme is that

Gather its herb collection period Herba Lobeliae Chinensis, clean, after washing, take advantage of fresh squeezing.Gained medicinal residues add the water of 1 ~ 5 times amount, Stirring 5 ~ 30min, filter press filter pressing extracting juice.Remaining medicinal residues are squeezed extracting juice again.Merge three medicine juice, with 40 ~ 120 mesh sieves Filter, obtain Herba Lobeliae Chinensis medicine juice.The Herba Lobeliae Chinensis medicine juice obtained is evaporated under the conditions of 40 ~ 75 DEG C relative density be 1.02 ~ The concentrated solution of 1.15, and this concentrated solution is spray-dried, intake air temperature is set as 90 ~ 140 DEG C, and air outlet temperature is 80 ~ 110 DEG C, collect desciccate, cross 60 ~ 100 mesh sieves after pulverizing, be vacuum-packed.

On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, decoction pieces manufacturer, the date of manufacture, The information such as Contents of Main Components, meridian distribution of property and flavor, function cure mainly, usage and dosage, toxic and side effects and contraindication.The included upper lotus of bag Thin layer differentiate collection of illustrative plates and/or high-efficient liquid phase character collection of illustrative plates, as " identity card " of product.Additionally, in the packaging bag of product, It is printed on Quick Response Code, the acquisition former plant photo of product, medical material photo, decoction pieces photo, character and micro-can be linked by scanning The information such as diagnostic characteristics.

The invention have benefit that:

The Herba Lobeliae Chinensis medical material of fresh collection, directly squeezes after cleaning washing, filters, concentrating under reduced pressure, spray drying, obtained powder End decoction pieces, can retain the effective ingredient in medical material to greatest extent.This decoction pieces volume compares to tradition decoction pieces volume significantly Ground reduces, vacuum packaging so that prepared slice quality is more stable, and beneficially accumulating and clinic is adjusted, and has very significantly society's meaning Justice and economic implications.

Detailed description of the invention

Embodiment 1

By the Herba Lobeliae Chinensis medical material of fresh collection, clean, wash silt with water, take advantage of using fresh herb squeezer squeezing extracting juice.Gained medicinal residues add 3 The tap water of times amount, stirs 20min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.By above-mentioned 3 times medicine juice merges, and filters with 100 eye mesh screens.Filtrate reduced in volume, temperature is set as 65 DEG C.Concentrating, gained extractum is the closeest When degree is 1.05, being spray-dried, intake air temperature is 140 DEG C, and air outlet temperature is 100 DEG C, collection spray drying thing, low-temperature grinding, Crossing 80 mesh sieves, moisture is not higher than 12%, packs, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package, and labeling is i.e. Can.

Embodiment 2

By the Herba Lobeliae Chinensis medical material of fresh collection, clean, wash silt with water, take advantage of using fresh herb squeezer squeezing extracting juice.Gained medicinal residues add 5 The tap water of times amount, stirs 30min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.By above-mentioned 3 times medicine juice merges, and filters with 80 eye mesh screens.Filtrate reduced in volume, temperature is set as 70 DEG C.Concentrating gained extractum relative density When being 1.10, being spray-dried, intake air temperature is 120 DEG C, and air outlet temperature is 90 DEG C, collects spray drying thing, low-temperature grinding, crosses 60 Mesh sieve, moisture is not higher than 12%, packs, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package, labeling.

Above example, is only the technological thought that this invention is described, it is impossible to limit protection scope of the present invention whereby all It is the technological thought proposed according to the present invention, any change done on the basis of technical scheme, each fall within present invention protection Within the scope of.

Claims

1. a Herba Lobeliae Chinensis fresh squeezing spray-dried powders decoction pieces and preparation technology thereof, it is characterised in that: adopt collection period Herba Lobeliae Chinensis Collecting its herb, clean, after washing, take advantage of fresh squeezing, medicinal residues add the water of 1 ~ 5 times amount, stir 5 ~ 30min, filter press filter pressing Extracting juice, remaining medicinal residues squeeze extracting juice again, merge three medicine juice, 40 ~ 120 mesh screen, obtain Herba Lobeliae Chinensis medicine juice.

A kind of Herba Lobeliae Chinensis fresh squeezing spray-dried powders decoction pieces the most according to claim 1 and preparation technology thereof, its feature exists In: the Herba Lobeliae Chinensis medicine juice obtained is evaporated under the conditions of 40 ~ 75 DEG C the concentrated solution that relative density is 1.02 ~ 1.15, and Being spray-dried by this concentrated solution, intake air temperature is set as 90 ~ 140 DEG C, and air outlet temperature is 80 ~ 110 DEG C, collects to be dried and produces Thing, crosses 60 ~ 100 mesh sieves, is vacuum-packed after pulverizing.