CN106723041A - 一种化橘红清咽含片及其制备方法 - Google Patents
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Abstract
本发明属于保健品领域，具体涉及一种化橘红清咽含片及其制备方法。含片由下列重量份数的原料制成：化橘红嫩果粉末15~20份，甘草8~16份，金银花6~14份，罗汉果4~9份，聚乙烯吡咯烷酮2.5~3.5份，聚乙二醇6000 2.5~3.5份,甘露醇25~35份，甜味剂0.2~0.8份。其制备方法包括以下步骤：( 1 ) 取化橘红嫩果粉末、甘草、金银花、罗汉果加水煎煮，滤过，浓缩，得稠膏；( 2 ) 依次加入聚乙烯吡咯烷酮（PVP）、聚乙二醇6000、甘露醇和甜味剂，混匀；60℃烘至水分在7％以下，冷却，压片，即得产品。本发明配方合理，疗效显著，无任何毒副作用，生产工艺简单，显著，无任何毒副作用，生产工艺简单，生产成本低。
Description
技术领域
本发明属于保健食品领域，具体涉及一种化橘红清咽含片及其制备方法。
背景技术
咽喉容易受环境和体内因素的影响而感染，引起咽喉发炎等问题，随着空气质量的恶化，咽喉发炎的发病率有增高的趋势。清咽是原卫生部批准的保健食品的功能项目之一，它所适用的人群便是日益增多的咽炎患者。化橘红具有化痰止咳、抗氧化和消炎等功效，既是传统中药又是保健食品，总黄酮占嫩果实干重的30%以上，其中柚皮苷占总黄酮的98%以上，其味道极苦。罗汉果含有罗汉果甜苷、多种氨基酸和维生素等药用成分，主治肺热痰火咳嗽、咽喉炎和扁桃体炎等，其甜度高、热量低而作为甜味剂广泛使用，可起到清咽和矫味的作用；甘草黄酮有明显的镇咳、祛痰作用，甘草甜素对化橘红柚皮苷的苦味起到矫味作用。化橘红干果泡水饮用，也可起清咽、消炎的作用。目前化橘红的产品主要是嫩果烘干成质地十分坚硬的橘红胎，要经热水浸泡十几分钟软化后才能切片、浸泡和饮用，加之柚皮苷的味道极苦，往往令消费者难以接受。润喉清咽产品的消费对象一般为慢性咽炎患者，这些患者多存在喉咙痒、刺痛、干咳等症状，用胶囊、内服片剂治疗不太适宜，治疗效果不好；食用茶或其它饮品对人体内部调节、预防咽喉不适效果也不错，但作用时间短；而含片可以长时间、直接地作用于患处，效果比较好，且含片还有利于携带、方便食用等优点，因此，目前已有的产品以含片居多，不少专家认为今后含片仍将是润喉清咽产品的主流剂型，还可以开发出更多新品种满足市场需要。
发明内容
本发明目的在于提供一种效果好且便于携带、食用方便等优点清咽的化橘红清咽含片及其制备方法，本发明的另一个目的在于提供该含片的制备方法。
本发明目的是通过如下技术方案实现：
一种化橘红清咽含片，由下列重量份数的原料制成：化橘红嫩果粉末15~20份，甘草8~16份，金银花6~14份，罗汉果4~9份，聚乙烯吡咯烷酮2.5~3.5份，聚乙二醇6000 2.5~3.5份,甘露醇25~35份，甜味剂0.2~0.8份；
化橘红嫩果粉末采用如下的方法获得：采摘约40天果龄的化橘红果实，切成厚度1.5~3.0mm的薄片，置60℃烘箱中烘干到恒重。
所述的化橘红果实，是广东省化州市道地出产的化州柚嫩果，直径5~6cm，鲜重45~55g，干重9~11g，它们的功能成分占干重的含量分别是：柚皮苷25~35%，野漆树苷 0.18~0.24 %，总黄酮25.6~35.2%。
所述的甜味剂为阿斯巴甜，所述聚乙烯吡咯烷酮（PVP）作为粘合剂；所述的聚乙二醇6000作为润滑剂；所述的甘露醇作为填充性辅料。
一种化橘红清咽含片的制备方法，按重量份数称取化橘红、甘草、金银花、罗汉果，分别粉碎，混合在一起；
加8~12倍量水，煎煮3次，每次1h，合并滤液，旋转蒸发减压得浓缩液，加乙醇至醇浓度为60％，静置4~10h，上清液减压回收乙醇后，浓缩为稠膏，依次加入聚乙烯吡咯烷酮（PVP）、聚乙二醇6000、甘露醇、阿斯巴甜混匀，60℃烘至恒重，粉碎过80目筛。
将粉末用压片机进行压片，压片后，将含片置于60℃环境中，干燥至水分添加量≤5％为止，将干燥好的含片放入塑料包装袋中，进行真空包装。
综上所述，由于采用了上述技术方案，本发明的有益效果是：
本发明清咽含片的各原料，化橘红化痰止咳、清肺利咽；金银花花清热解毒；甘草止咳平喘、抗炎；罗汉果清热、袪痰、抗炎作用。四药配伍具有清热润喉、润肺利咽之功效，三辅料能有效平去柚皮苷的苦味。其配方科学、合理。本发明清热润喉清咽含片中的有效成分通过口含慢慢地作用于咽喉部，达到良好的润喉清咽效果，既突破了中药传统煎服的瓶颈，很好的融入现代人的生活，也克服了西药在治疗过程中抗生素滥用引起的各种问题。该润喉清咽含片口感好，生产成本低，产品稳定性好，适合于大批量生产。
具体实施方式
下面将结合本发明实施例，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
为了彻底理解本发明，将在下列的描述中提出详细的步骤，以便阐释本发明的技术方案。本发明的较佳实施例详细描述如下，然而除了这些详细描述外，本发明还可以具有其他实施方式。
实施例1
本发明提供了一种以化橘红嫩果做主料，甘草、金银花和罗汉果作辅料制备清咽含片的方法，包括以下步骤：
步骤S1：采摘约40天果龄化的化橘红果实；化橘红果实，是广东省化州市道地出产的化州柚嫩果；
步骤S2：切成厚度1.5~3.0mm的薄片；
步骤S3：置60℃烘箱中烘干到恒重，粉碎并过40目筛；
步骤S4：分别粉碎甘草、金银花和罗汉果，并过40目筛得到化橘红嫩果粉末；
步骤S5：按重量份数称取化橘红嫩果粉末20份，甘草10份，金银花6份，罗汉果5份，混合在一起；
加10倍量水，煎煮2次，每次1h，合并滤液，旋转蒸发减压得浓缩液，加乙醇至醇浓度为60％，静置5 h，上清液减压回收乙醇后，浓缩为稠膏。
在上述稠膏中依次加入聚乙烯吡咯烷酮（PVP）2.5重量份，聚乙二醇6000 2.5重量份, 甘露醇35重量份，阿斯巴甜0.5重量份，混匀，60℃烘至恒重，粉碎过80目筛。
将粉末用压片机进行压片，每片1.5克，将含片置于60℃环境中，干燥至水分添加量≤ 5％为止，将干燥好的含片放入塑料包装袋中，进行真空包装。
采用上述方法制得的实施例样品，生产工艺简单，质量稳定，所制得的润喉清咽含片，形状完整，表面光滑，呈淡黄色至棕黄色，色泽均匀一致，具有化橘红和罗汉果的清香风味，甘甜可口，入口细腻柔顺，有清凉感，溶化性能良好。将上述样品用于咽干、疼痛、声音嘶哑、甚或失音、咽痒、干咳少痰、吞咽困难、咽喉部有异物感等患者，均取得良好效果。
以上对本发明的较佳实施例进行了描述。需要理解的是，本发明并不局限于上述特定实施方式，其中未尽详细描述的设备和结构应该理解为用本领域中的普通方式予以实施；任何熟悉本领域的技术人员，在不脱离本发明技术方案范围情况下，都可利用上述揭示的方法和技术内容对本发明技术方案做出许多可能的变动和修饰，或修改为等同变化的等效实施例，这并不影响本发明的实质内容。因此，凡是未脱离本发明技术方案的内容，依据本发明的技术实质对以上实施例所做的任何简单修改、等同变化及修饰，均仍属于本发明技术方案保护的范围内。
Claims (4)
1.一种化橘红清咽含片，其特征在于，由下列重量份数的原料制成：化橘红嫩果粉末15~20份，甘草8~16份，金银花6~14份，罗汉果4~9份，聚乙烯吡咯烷酮2.5~3.5份，聚乙二醇6000 2.5~3.5份, 甘露醇25~35份，甜味剂0.2~0.8份；
化橘红嫩果粉末采用如下的方法获得：采摘约40天果龄的化橘红果实，切成厚度1.5~3.0mm的薄片，置60℃烘箱中烘干到恒重。
2.如权利要求1所述的一种化橘红清咽含片，其特征在于，化橘红果实是广东省化州市道地出产的化州柚嫩果，直径5~6cm，鲜重45~55g，干重9~11g，它们的功能成分占干重的含量分别是：柚皮苷25~35%，野漆树苷0.18~0.24 %，总黄酮25.6~35.2%。
3.如权利要求1所述的一种化橘红清咽含片，其特征在于，所述的甜味剂为阿斯巴甜。
4.权利要求1所述的一种化橘红清咽含片的制备方法，其特征在于，其包括以下步骤：
（1）按重量份数称取化橘红嫩果粉末、甘草、金银花、罗汉果，分别粉碎，混合在一起；
（2）加8~12倍量水，煎煮3次，每次1h，合并滤液，旋转蒸发减压得浓缩液，加乙醇至醇浓度为60％，静置4-10h，上清液减压回收乙醇后，浓缩为稠膏，依次加入聚乙烯吡咯烷酮、聚乙二醇6000、甘露醇、甜味剂，混匀，60℃烘至恒重，粉碎过80目筛；
（3）将粉末用压片机进行压片，压片后，将含片置于60℃中，干燥至水分含量≤ 5％为止，将干燥后的含片放入塑料包装袋中，进行真空包装。
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