CN106488910B - Kras g12c的抑制剂 - Google Patents

Kras g12c的抑制剂 Download PDF

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Publication number
CN106488910B
CN106488910B CN201480055783.1A CN201480055783A CN106488910B CN 106488910 B CN106488910 B CN 106488910B CN 201480055783 A CN201480055783 A CN 201480055783A CN 106488910 B CN106488910 B CN 106488910B
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compound
hydrocarbyl
group
cancer
compounds
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CN106488910A (zh
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李连升
冯军
吴涛
任平达
刘毅
刘源
龙筠
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Araxes Pharma LLC
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  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CN201480055783.1A 2013-10-10 2014-10-10 Kras g12c的抑制剂 Active CN106488910B (zh)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361889460P 2013-10-10 2013-10-10
US61/889,460 2013-10-10
US201462034619P 2014-08-07 2014-08-07
US62/034,619 2014-08-07
US201462052366P 2014-09-18 2014-09-18
US62/052,366 2014-09-18
TW103135318 2014-10-09
JO289/2014 2014-10-09
JOP/2014/0289A JO3805B1 (ar) 2013-10-10 2014-10-09 مثبطات كراس جي12سي
TW103135318A TWI659021B (zh) 2013-10-10 2014-10-09 Ｋｒａｓ ｇ１２ｃ之抑制劑
PCT/US2014/060036 WO2015054572A1 (en) 2013-10-10 2014-10-10 Inhibitors of kras g12c

Publications (2)

Publication Number Publication Date
CN106488910A CN106488910A (zh) 2017-03-08
CN106488910B true CN106488910B (zh) 2020-07-31

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EP (2) EP3055290B1 (https=)
JP (1) JP6559123B2 (https=)
KR (1) KR20160076519A (https=)
CN (1) CN106488910B (https=)
AU (1) AU2014331794C1 (https=)
BR (1) BR112016008016B8 (https=)
CA (1) CA2926328C (https=)
EA (1) EA033689B9 (https=)
IL (1) IL244699B (https=)
MX (1) MX380928B (https=)
NI (1) NI201600049A (https=)
NO (1) NO20160646A1 (https=)
PH (1) PH12016500538B1 (https=)
SG (1) SG11201602662YA (https=)
UA (1) UA119971C2 (https=)
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JO3805B1 (ar) * 2013-10-10 2021-01-31 Araxes Pharma Llc مثبطات كراس جي12سي
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