CN106459048A - 吡唑并吡啶类和吡唑并嘧啶类 - Google Patents

吡唑并吡啶类和吡唑并嘧啶类 Download PDF

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Publication number
CN106459048A
CN106459048A CN201580036211.3A CN201580036211A CN106459048A CN 106459048 A CN106459048 A CN 106459048A CN 201580036211 A CN201580036211 A CN 201580036211A CN 106459048 A CN106459048 A CN 106459048A
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China
Prior art keywords
amino
methyl
phenyl
pyrazolo
fluoro
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Pending
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CN201580036211.3A
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English (en)
Chinese (zh)
Inventor
J.W.西
C.M.德恩哈德特
P.琼斯
Y.A.萨尼斯
J.W.斯特罗巴赫
F.M.沃肯哈特
G.A.怀特洛克
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Pfizer Inc
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Pfizer Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53264695&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN106459048(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of CN106459048A publication Critical patent/CN106459048A/zh
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
CN201580036211.3A 2014-05-14 2015-04-30 吡唑并吡啶类和吡唑并嘧啶类 Pending CN106459048A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461993138P 2014-05-14 2014-05-14
US61/993138 2014-05-14
PCT/IB2015/053174 WO2015173683A1 (en) 2014-05-14 2015-04-30 Pyrazolopyridines and pyrazolopyrimidines

Publications (1)

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CN106459048A true CN106459048A (zh) 2017-02-22

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US (2) US9518052B2 (https=)
EP (1) EP3143021B1 (https=)
JP (1) JP6663857B2 (https=)
KR (1) KR20170002623A (https=)
CN (1) CN106459048A (https=)
AP (1) AP2016009562A0 (https=)
AR (1) AR100438A1 (https=)
AU (1) AU2015260905A1 (https=)
CA (1) CA2948587C (https=)
CL (1) CL2016002888A1 (https=)
CR (1) CR20160525A (https=)
CU (1) CU20160167A7 (https=)
DO (1) DOP2016000298A (https=)
EA (1) EA201650029A1 (https=)
EC (1) ECSP16087271A (https=)
ES (1) ES2737696T3 (https=)
GE (2) GEAP201814322A (https=)
IL (1) IL248970A0 (https=)
MD (1) MD20160121A2 (https=)
MX (1) MX2016014878A (https=)
NI (1) NI201600170A (https=)
PE (1) PE20161475A1 (https=)
PH (1) PH12016502228A1 (https=)
SG (1) SG11201609139WA (https=)
SV (1) SV2016005318A (https=)
TN (1) TN2016000503A1 (https=)
TW (1) TWI591067B (https=)
UY (1) UY36121A (https=)
WO (1) WO2015173683A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
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CN110833555A (zh) * 2018-08-15 2020-02-25 广西梧州制药（集团）股份有限公司 吡唑并嘧啶衍生物在治疗溃疡性结肠炎的用途
CN111548269A (zh) * 2020-04-29 2020-08-18 兰州大学 一种二芳基甲烷结构化合物的制备方法
CN113101975A (zh) * 2020-01-13 2021-07-13 万华化学集团股份有限公司 一种多膦配体催化剂体系及其在乙烯齐聚反应的应用
CN113121509A (zh) * 2019-12-30 2021-07-16 路良 Jak抑制剂化合物及其用途
CN113480543A (zh) * 2021-07-07 2021-10-08 无锡市第二人民医院 2,6,8-多取代咪唑并[1,2-a]吡嗪及其合成方法和应用
CN115557947A (zh) * 2021-07-02 2023-01-03 成都百裕制药股份有限公司 吡唑并[4,3-c]吡啶衍生物及其在医药上的应用
CN116075515A (zh) * 2020-07-07 2023-05-05 辉瑞大药厂 可用于治疗呼吸道合胞病毒感染的苯二氮杂䓬衍生物

Families Citing this family (31)

* Cited by examiner, † Cited by third party
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TWI714528B (zh) 2014-05-14 2021-01-01 瑞士商諾華公司 甲醯胺衍生物
CR20160525A (es) 2014-05-14 2016-12-20 Pfizer Pirazolopiridinas y pirazolopirimidinas
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US10556901B2 (en) 2015-11-03 2020-02-11 Topivert Pharma Limited 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as Janus kinase inhibitors
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