CN106008355B - 化合物及其作为bace抑制剂的用途 - Google Patents

化合物及其作为bace抑制剂的用途 Download PDF

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CN106008355B
CN106008355B CN201610341918.1A CN201610341918A CN106008355B CN 106008355 B CN106008355 B CN 106008355B CN 201610341918 A CN201610341918 A CN 201610341918A CN 106008355 B CN106008355 B CN 106008355B
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methyl
imidazoles
spiral shell
indenes
hexamethylene
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Chinese (zh)
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CN106008355A (zh
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G.斯杰伊克
S.卡尔斯特雷姆
A.科斯
K.科莫丁
M.内雷夫
L.奥伊伯格
L.拉科斯
L.桑德伯格
F.塞格梅布勒
P.塞德曼
B-M.斯瓦恩
S.冯伯格
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AstraZeneca AB
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    • A61K31/4965—Non-condensed pyrazines
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    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN201610341918.1A 2010-12-22 2011-12-21 化合物及其作为bace抑制剂的用途 Active CN106008355B (zh)

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US201061425852P 2010-12-22 2010-12-22
US61/425852 2010-12-22
US201161529620P 2011-08-31 2011-08-31
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