CN105816423A - 依达拉奉剂型 - Google Patents
依达拉奉剂型 Download PDFInfo
- Publication number
- CN105816423A CN105816423A CN201610149832.9A CN201610149832A CN105816423A CN 105816423 A CN105816423 A CN 105816423A CN 201610149832 A CN201610149832 A CN 201610149832A CN 105816423 A CN105816423 A CN 105816423A
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- preparation
- lipid
- edaravone
- drug delivery
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Abstract
Description
成分 | 数量 |
依达拉奉 | 10mg/ml |
CapryolTM PGMC | 30% |
Cremophor RH 40 | 23.33% |
Labrasol:TPGS 1000(4:1) | 23.33% |
Transcutol P | 23.33% |
成分 | 数量 |
依达拉奉 | 10mg/ml |
CapryolTM PGMC | 30% |
Cremophor RH 40 | 23.33% |
Labrasol:TPGS 1000(4:1) | 23.33% |
Transcutol P | 23.33% |
Aerosil 200(吸附剂) | 5%w/v |
成分 | 数量 |
依达拉奉 | 10mg/ml |
CapryolTM PGMC | 30% |
Cremophor RH 40 | 23.33% |
Labrasol | 23.33% |
Transcutol P | 23.33% |
成分 | 数量 |
依达拉奉 | 10mg/ml |
CapryolTM PGMC | 30% |
Labrasol | 46.66% |
Transcutol P | 23.33% |
Aerosil 200(吸附剂) | 5%w/v |
成分 | 数量 |
依达拉奉 | 10mg/ml |
CapryolTM PGMC | 30% |
Cremophor RH 40 | 23.33% |
Labrasol:TPGS 1000(4:1) | 23.33% |
Transcutol P | 23.33% |
水 | 足量 |
成分 | 数量(mg) |
依达拉奉 | 100 |
Soluplus:TPGS 1000 | 500:200 |
PBS(pH 7.4) | 10ml |
成分 | 数量(mg) |
依达拉奉 | 100 |
Soluplus:TPGS 1000 | 500:75 |
成分 | 数量(mg) |
依达拉奉 | 100 |
Soluplus | 500 |
成分 | 数量 |
依达拉奉 | 20mg/ml |
Cremophor RH 40 | 250mg |
PEG 300 | 250mg |
TPGS 1000 | 125mg |
水 | 375mg |
成分 | 数量 |
依达拉奉 | 20mg/ml |
Labrasol | 500mg |
TPGS 1000 | 125mg |
水 | 375mg |
成分 | 数量 |
依达拉奉 | 20mg/ml |
PEG 300 | 500mg |
TPGS 1000 | 125mg |
水 | 375mg |
Claims (49)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110900809.XA CN113768879A (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN201810908492.2A CN109125261B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN202010685163.3A CN111840218B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN201610149832.9A CN105816423B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
EP17765892.9A EP3431075A4 (en) | 2016-03-16 | 2017-04-21 | GALENIC FORM OF EDARAVONE |
US16/084,668 US11020375B2 (en) | 2016-03-16 | 2017-04-21 | Edaravone dosage form |
EP23203751.5A EP4289482A3 (en) | 2016-03-16 | 2017-04-21 | Edaravone dosage form |
PCT/CN2017/081405 WO2017157350A1 (zh) | 2016-03-16 | 2017-04-21 | 依达拉奉剂型 |
SG11201808019WA SG11201808019WA (en) | 2016-03-16 | 2017-04-21 | Edaravone formulations |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610149832.9A CN105816423B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010685163.3A Division CN111840218B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN202110900809.XA Division CN113768879A (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN201810908492.2A Division CN109125261B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105816423A true CN105816423A (zh) | 2016-08-03 |
CN105816423B CN105816423B (zh) | 2018-07-20 |
Family
ID=56523472
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810908492.2A Active CN109125261B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN202110900809.XA Pending CN113768879A (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN202010685163.3A Active CN111840218B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN201610149832.9A Active CN105816423B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810908492.2A Active CN109125261B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN202110900809.XA Pending CN113768879A (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
CN202010685163.3A Active CN111840218B (zh) | 2016-03-16 | 2016-03-16 | 依达拉奉剂型 |
Country Status (5)
Country | Link |
---|---|
US (1) | US11020375B2 (zh) |
EP (2) | EP4289482A3 (zh) |
CN (4) | CN109125261B (zh) |
SG (1) | SG11201808019WA (zh) |
WO (1) | WO2017157350A1 (zh) |
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WO2017157350A1 (zh) * | 2016-03-16 | 2017-09-21 | 福建天泰医药科技有限公司 | 依达拉奉剂型 |
CN107913249A (zh) * | 2017-11-23 | 2018-04-17 | 广东医科大学 | 一种组合物及含有该组合物的纳米胶束与应用 |
CN108066284A (zh) * | 2016-11-14 | 2018-05-25 | 复旦大学 | 一种用于缺血性脑卒中治疗的激动胶束 |
WO2018134243A1 (en) | 2017-01-17 | 2018-07-26 | Treeway Tw001 B.V. | Treatment comprising oral or gastric administration of edaravone |
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CN108403691A (zh) * | 2018-03-13 | 2018-08-17 | 南京中医药大学 | 一种依达拉奉的新用途 |
CN110384656A (zh) * | 2018-04-19 | 2019-10-29 | 上海现代药物制剂工程研究中心有限公司 | 依达拉奉鼻腔给药组合物及其鼻给药制剂制备方法 |
WO2020093896A1 (en) * | 2018-11-06 | 2020-05-14 | Beijing Innocare Pharma Tech Co., Ltd. | Amorphous solid dispersion comprising 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide |
US10987390B2 (en) * | 2018-12-06 | 2021-04-27 | Maryam Rahimi | Plant stem cell product treatments |
CN112969459A (zh) * | 2018-11-02 | 2021-06-15 | 田边三菱制药株式会社 | 用于口服给药的依达拉奉混悬剂 |
CN113440484A (zh) * | 2020-03-26 | 2021-09-28 | 苏州澳宗生物科技有限公司 | 一种依达拉奉固体分散体的制备方法 |
CN114099499A (zh) * | 2020-08-26 | 2022-03-01 | 上海博志研新药物技术有限公司 | 依达拉奉口服持续释放组合物、制备方法及应用 |
CN114099500A (zh) * | 2020-08-26 | 2022-03-01 | 上海博志研新药物技术有限公司 | 依达拉奉缓释药物组合物、制备方法及应用 |
CN115607545A (zh) * | 2021-10-22 | 2023-01-17 | 苏州澳宗生物科技有限公司 | 依达拉奉在自闭症谱系障碍治疗中的应用 |
RU2810789C2 (ru) * | 2018-11-02 | 2023-12-28 | Мицубиси Танабе Фарма Корпорейшн | Суспензия эдаравона для перорального введения |
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JPWO2022102737A1 (zh) * | 2020-11-12 | 2022-05-19 | ||
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WO2017157350A1 (zh) * | 2016-03-16 | 2017-09-21 | 福建天泰医药科技有限公司 | 依达拉奉剂型 |
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CN112969459A (zh) * | 2018-11-02 | 2021-06-15 | 田边三菱制药株式会社 | 用于口服给药的依达拉奉混悬剂 |
RU2810789C2 (ru) * | 2018-11-02 | 2023-12-28 | Мицубиси Танабе Фарма Корпорейшн | Суспензия эдаравона для перорального введения |
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WO2020093896A1 (en) * | 2018-11-06 | 2020-05-14 | Beijing Innocare Pharma Tech Co., Ltd. | Amorphous solid dispersion comprising 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide |
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WO2023066330A1 (zh) | 2021-10-22 | 2023-04-27 | 苏州澳宗生物科技有限公司 | 依达拉奉在自闭症谱系障碍治疗中的应用 |
Also Published As
Publication number | Publication date |
---|---|
SG11201808019WA (en) | 2018-10-30 |
EP4289482A3 (en) | 2024-06-19 |
CN109125261B (zh) | 2021-11-30 |
US11020375B2 (en) | 2021-06-01 |
EP3431075A1 (en) | 2019-01-23 |
CN111840218A (zh) | 2020-10-30 |
WO2017157350A1 (zh) | 2017-09-21 |
CN105816423B (zh) | 2018-07-20 |
CN109125261A (zh) | 2019-01-04 |
CN113768879A (zh) | 2021-12-10 |
US20190083463A1 (en) | 2019-03-21 |
EP4289482A2 (en) | 2023-12-13 |
EP3431075A4 (en) | 2020-01-22 |
CN111840218B (zh) | 2022-07-12 |
EP4289482A9 (en) | 2024-05-29 |
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