CN105712977B - 作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物 - Google Patents

作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物 Download PDF

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Publication number
CN105712977B
CN105712977B CN201610094782.9A CN201610094782A CN105712977B CN 105712977 B CN105712977 B CN 105712977B CN 201610094782 A CN201610094782 A CN 201610094782A CN 105712977 B CN105712977 B CN 105712977B
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disorders
diazepan
disorder
compounds
yloxy
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CN105712977A (zh
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M.A.莱塔维克
E.M.斯托金
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Janssen Pharmaceutica NV
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    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
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    • C07—ORGANIC CHEMISTRY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN201610094782.9A 2007-11-20 2008-11-17 作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物 Expired - Fee Related CN105712977B (zh)

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US98924607P 2007-11-20 2007-11-20
US60/989246 2007-11-20
CN200880117055A CN101868454A (zh) 2007-11-20 2008-11-17 作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物

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CN105712977A CN105712977A (zh) 2016-06-29
CN105712977B true CN105712977B (zh) 2021-06-29

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CN200880117055A Pending CN101868454A (zh) 2007-11-20 2008-11-17 作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物

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US (1) US8883776B2 (enExample)
EP (1) EP2222664B1 (enExample)
JP (1) JP5498390B2 (enExample)
KR (1) KR101546712B1 (enExample)
CN (2) CN105712977B (enExample)
AR (2) AR069387A1 (enExample)
AU (1) AU2008326561B2 (enExample)
BR (1) BRPI0820481A2 (enExample)
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CN102015636B (zh) * 2008-05-08 2014-08-13 埃沃特克股份有限公司 作为组胺h3受体拮抗剂的氮杂环丁烷类和环丁烷类化合物
ES2625261T3 (es) * 2009-03-18 2017-07-19 Janssen Pharmaceutica, N.V. Procedimiento para la preparación de moduladores de receptores H3 de histamina
JP2013505297A (ja) * 2009-09-21 2013-02-14 ヴァンダービルト ユニバーシティー ｍＧｌｕＲ５の正のアロステリック調節因子としてのＯ−ベンジルニコチンアミド類似体
PL2729130T3 (pl) 2011-07-07 2018-02-28 Janssen Sciences Ireland Uc Preparaty kombinowane darunawiru

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MY158253A (en) 2016-09-30
CA2706328C (en) 2016-04-19
AR110977A2 (es) 2019-05-22
CN105712977A (zh) 2016-06-29
CO6210700A2 (es) 2010-10-20
TW200936579A (en) 2009-09-01
NZ584998A (en) 2012-08-31
AU2008326561A1 (en) 2009-05-28
EP2222664A1 (en) 2010-09-01
JP5498390B2 (ja) 2014-05-21
HK1147994A1 (en) 2011-08-26
US8883776B2 (en) 2014-11-11
EP2222664B1 (en) 2014-10-29
EA201070637A1 (ru) 2010-12-30
BRPI0820481A2 (pt) 2015-06-16
KR101546712B1 (ko) 2015-08-24
MX2010005488A (es) 2010-06-01
KR20100098636A (ko) 2010-09-08
JP2011503233A (ja) 2011-01-27
ZA201004334B (en) 2011-10-26
CR11529A (es) 2012-10-25
US20090131415A1 (en) 2009-05-21
WO2009067401A1 (en) 2009-05-28
CL2008003465A1 (es) 2009-03-06
ECSP10010190A (es) 2010-06-29
AU2008326561B2 (en) 2013-12-05
NI201000086A (es) 2011-03-17
UA103468C2 (ru) 2013-10-25
CA2706328A1 (en) 2009-05-28
TWI491604B (zh) 2015-07-11
EA018582B1 (ru) 2013-09-30
AR069387A1 (es) 2010-01-20
CN101868454A (zh) 2010-10-20

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