CN105147550A - Whitening and moisture-preserving mask liquid containing common nostoc extract and preparation method thereof - Google Patents
Whitening and moisture-preserving mask liquid containing common nostoc extract and preparation method thereof Download PDFInfo
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- CN105147550A CN105147550A CN201510570868.XA CN201510570868A CN105147550A CN 105147550 A CN105147550 A CN 105147550A CN 201510570868 A CN201510570868 A CN 201510570868A CN 105147550 A CN105147550 A CN 105147550A
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- China
- Prior art keywords
- extract
- radix
- sphaeroids kutz
- root extract
- liquid containing
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- Granted
Links
- 241000192656 Nostoc Species 0.000 title claims abstract description 65
- 230000002087 whitening effect Effects 0.000 title claims abstract description 49
- 239000007788 liquid Substances 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 238000000605 extraction Methods 0.000 title description 8
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 39
- 235000009388 Parthenocissus quinquefolia Nutrition 0.000 claims abstract description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 22
- 229940111047 opUNTia streptacantha stem extract Drugs 0.000 claims abstract description 17
- 239000002904 solvent Substances 0.000 claims abstract description 17
- 239000002562 thickening agent Substances 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims abstract description 16
- 230000003020 moisturizing effect Effects 0.000 claims description 33
- 241000563984 Ampelopsis Species 0.000 claims description 22
- 230000002421 anti-septic effect Effects 0.000 claims description 16
- 239000000080 wetting agent Substances 0.000 claims description 16
- 229920001503 Glucan Polymers 0.000 claims description 12
- TWNIBLMWSKIRAT-VFUOTHLCSA-N levoglucosan Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@H]2CO[C@@H]1O2 TWNIBLMWSKIRAT-VFUOTHLCSA-N 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 11
- -1 HANSHENGJIAO Polymers 0.000 claims description 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 9
- 230000002829 reductive effect Effects 0.000 claims description 8
- 230000008961 swelling Effects 0.000 claims description 8
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims description 5
- DHHFDKNIEVKVKS-MVUYWVKGSA-N Betanin Natural products O=C(O)[C@@H]1NC(C(=O)O)=C/C(=C\C=[N+]/2\[C@@H](C(=O)[O-])Cc3c\2cc(O)c(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)c3)/C1 DHHFDKNIEVKVKS-MVUYWVKGSA-N 0.000 claims description 4
- DHHFDKNIEVKVKS-FMOSSLLZSA-N Betanin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1)O)=CC(C[C@H]2C([O-])=O)=C1[N+]2=C\C=C\1C=C(C(O)=O)N[C@H](C(O)=O)C/1 DHHFDKNIEVKVKS-FMOSSLLZSA-N 0.000 claims description 4
- HSRJKNPTNIJEKV-UHFFFAOYSA-N Guaifenesin Chemical compound COC1=CC=CC=C1OCC(O)CO HSRJKNPTNIJEKV-UHFFFAOYSA-N 0.000 claims description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 4
- 235000001014 amino acid Nutrition 0.000 claims description 4
- 150000001413 amino acids Chemical class 0.000 claims description 4
- 239000001654 beetroot red Substances 0.000 claims description 4
- 235000012677 beetroot red Nutrition 0.000 claims description 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 4
- 235000002185 betanin Nutrition 0.000 claims description 4
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical class CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 4
- 238000004108 freeze drying Methods 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 238000003815 supercritical carbon dioxide extraction Methods 0.000 claims description 4
- MXOAEAUPQDYUQM-QMMMGPOBSA-N (S)-chlorphenesin Chemical compound OC[C@H](O)COC1=CC=C(Cl)C=C1 MXOAEAUPQDYUQM-QMMMGPOBSA-N 0.000 claims description 3
- FEBUJFMRSBAMES-UHFFFAOYSA-N 2-[(2-{[3,5-dihydroxy-2-(hydroxymethyl)-6-phosphanyloxan-4-yl]oxy}-3,5-dihydroxy-6-({[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-4-yl)oxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl phosphinite Chemical compound OC1C(O)C(O)C(CO)OC1OCC1C(O)C(OC2C(C(OP)C(O)C(CO)O2)O)C(O)C(OC2C(C(CO)OC(P)C2O)O)O1 FEBUJFMRSBAMES-UHFFFAOYSA-N 0.000 claims description 3
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 3
- 229920002690 Polyoxyl 40 HydrogenatedCastorOil Polymers 0.000 claims description 3
- 229920002305 Schizophyllan Polymers 0.000 claims description 3
- 229960003993 chlorphenesin Drugs 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 229940071826 hydroxyethyl cellulose Drugs 0.000 claims description 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 3
- 150000002576 ketones Chemical class 0.000 claims description 3
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 claims description 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 2
- 239000005711 Benzoic acid Substances 0.000 claims description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- 229920001090 Polyaminopropyl biguanide Polymers 0.000 claims description 2
- 229920001213 Polysorbate 20 Polymers 0.000 claims description 2
- 229920002125 Sokalan® Polymers 0.000 claims description 2
- 235000010233 benzoic acid Nutrition 0.000 claims description 2
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 2
- 239000004202 carbamide Substances 0.000 claims description 2
- 235000013877 carbamide Nutrition 0.000 claims description 2
- 229960001631 carbomer Drugs 0.000 claims description 2
- INSRQEMEVAMETL-UHFFFAOYSA-N decane-1,1-diol Chemical compound CCCCCCCCCC(O)O INSRQEMEVAMETL-UHFFFAOYSA-N 0.000 claims description 2
- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 claims description 2
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims description 2
- 239000012467 final product Substances 0.000 claims description 2
- 150000004676 glycans Chemical class 0.000 claims description 2
- ZCTXEAQXZGPWFG-UHFFFAOYSA-N imidurea Chemical compound O=C1NC(=O)N(CO)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO ZCTXEAQXZGPWFG-UHFFFAOYSA-N 0.000 claims description 2
- 229910052740 iodine Inorganic materials 0.000 claims description 2
- 239000011630 iodine Substances 0.000 claims description 2
- KRPAJLYSLFNDOA-UHFFFAOYSA-N mephenesin carbamate Chemical compound CC1=CC=CC=C1OCC(O)COC(N)=O KRPAJLYSLFNDOA-UHFFFAOYSA-N 0.000 claims description 2
- 229950006838 mephenesin carbamate Drugs 0.000 claims description 2
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims description 2
- 150000002772 monosaccharides Chemical class 0.000 claims description 2
- 229960005323 phenoxyethanol Drugs 0.000 claims description 2
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 claims description 2
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 2
- 229940093424 polyaminopropyl biguanide Drugs 0.000 claims description 2
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims description 2
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims description 2
- 229920001451 polypropylene glycol Polymers 0.000 claims description 2
- 229920001282 polysaccharide Polymers 0.000 claims description 2
- 239000005017 polysaccharide Substances 0.000 claims description 2
- 239000001509 sodium citrate Substances 0.000 claims description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 2
- 239000004334 sorbic acid Substances 0.000 claims description 2
- 235000010199 sorbic acid Nutrition 0.000 claims description 2
- 229940075582 sorbic acid Drugs 0.000 claims description 2
- 239000000600 sorbitol Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 13
- 238000012360 testing method Methods 0.000 abstract description 7
- 230000003266 anti-allergic effect Effects 0.000 abstract description 2
- 239000003755 preservative agent Substances 0.000 abstract 2
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 229920002498 Beta-glucan Polymers 0.000 abstract 1
- 241001313857 Bletilla striata Species 0.000 abstract 1
- 241000219099 Parthenocissus quinquefolia Species 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 239000000686 essence Substances 0.000 abstract 1
- 231100000957 no side effect Toxicity 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 18
- 239000000047 product Substances 0.000 description 11
- 102000003425 Tyrosinase Human genes 0.000 description 8
- 108060008724 Tyrosinase Proteins 0.000 description 8
- 239000000706 filtrate Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 5
- 230000001815 facial effect Effects 0.000 description 5
- 230000002401 inhibitory effect Effects 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 239000002537 cosmetic Substances 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 239000002244 precipitate Substances 0.000 description 4
- 206010040880 Skin irritation Diseases 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 238000010298 pulverizing process Methods 0.000 description 3
- 230000036556 skin irritation Effects 0.000 description 3
- 231100000475 skin irritation Toxicity 0.000 description 3
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 244000221569 Opuntia streptacantha Species 0.000 description 2
- 235000000771 Opuntia streptacantha Nutrition 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 230000001351 cycling effect Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- 238000011068 loading method Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000000376 reactant Substances 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 description 1
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 235000011201 Ginkgo Nutrition 0.000 description 1
- 244000194101 Ginkgo biloba Species 0.000 description 1
- 235000008100 Ginkgo biloba Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- AGBQKNBQESQNJD-UHFFFAOYSA-N alpha-Lipoic acid Natural products OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
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- 229910021641 deionized water Inorganic materials 0.000 description 1
- OWZREIFADZCYQD-NSHGMRRFSA-N deltamethrin Chemical compound CC1(C)[C@@H](C=C(Br)Br)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 OWZREIFADZCYQD-NSHGMRRFSA-N 0.000 description 1
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- 239000008103 glucose Substances 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- ACCCMOQWYVYDOT-UHFFFAOYSA-N hexane-1,1-diol Chemical compound CCCCCC(O)O ACCCMOQWYVYDOT-UHFFFAOYSA-N 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229960003639 laurocapram Drugs 0.000 description 1
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Landscapes
- Cosmetics (AREA)
Abstract
The invention relates to whitening and moisture-preserving mask liquid containing common nostoc extract and a preparation method thereof. The raw materials of the whitening and moisture-preserving mask liquid comprise the common nostoc extract, a moisture-preserving agent, NT-7WAN, oat beta-glucan, radix ampelopsis root extract, white atractylodes rhizome root and stem extract, bletilla striata root extract, rhizoma nardostachyos extract, opuntia streptacantha stem extract, radix ophiopogonis root extract, radix sophorae flavescentis root extract, a chelating agent, a solubilizing agent, a preservative, a thickening agent, essence, citric acid and water. The mask liquid provided by the invention has the effects of whitening and preserving moisture and increasing the elasticity of skins, so that the skins are fine, smooth and glossy; the mask liquid passes an anti-allergy test, has a remarkable whitening effect, has no side effect, is safe and reliable and can be used for a long period as a mask type skin-protecting product.
Description
Technical field
The present invention relates to daily cosmetics field, particularly a kind of whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive and preparation method thereof.
Background technology
Along with growth in the living standard, there has been higher requirement in consumer to whitening product, and particularly in beauty and skin care market, Asia, whitening is still that consumer pays close attention to the most.But current skin care item market, needed for cleawhite pack ubiquity, effect component is single, product stability is poor, whitening effect is not good, even there is the defects such as toxic and side effects.
Nostoc is as the unique algae of China, and edible and medicinal use is with a long history, but it does not arouse enough attention in the application in personal care articles field.
Find through retrieval, publication number is that the application for a patent for invention of CN101822630A discloses a kind of nostoc sphaeroids kutz extractive and the application in cosmetics thereof, this extract in preparation method for getting the dry frond of Nostoc, sieve after crushed, add water in advance swelling a few hours, or directly add water boil extraction for several times with fresh goods Nostoc, collecting by filtration filtrate, filtrate is through concentrating under reduced pressure, concentrated also precipitate with ethanol, centrifugally be precipitated thing, precipitate drying becomes nostoc sphaeroids kutz extractive, this nostoc sphaeroids kutz extractive has water conservation, beauty functions, be added in cosmetics, can play to effect of skin moisture-keeping.
Summary of the invention
On the basis of existing technology, the invention provides a kind of whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive and preparation method thereof.
For achieving the above object, the technical scheme that concrete employing is following:
A kind of whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive, its raw material comprises by weight: nostoc sphaeroids kutz extractive 0.005-2.0 part, wetting agent 1-30 part, NT-7WAN0.5-10 part, avenabeta glucosan 0.1-5 part, Radix Ampelopsis root extract 0.01-1 part, Rhizoma Atractylodis Macrocephalae rhizome extract 0.01-1 part, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.03-3 part, Radix Et Rhizoma Nardostachyos extract 0.05-5 part, Opuntia Streptacantha stem extract 0.01-1 part, Radix Ophiopogonis root extract 0.01-1 part, radix sophorae extract 0.01-1 part, chelating agen 0.01-0.3 part, solubilizing agent 0.01-1 part, antiseptic 0.01-1 part, thickening agent 0.01-1 part, essence 0.01-1 part, citric acid 0.0001-0.1 part, water complements to 100 parts.
Described NT-7WAN is commercially available, and supplier is the glad Chemical Industry Science Co., Ltd of upper oceanic rise.Composition main in NT-7WAN comprises thioctic acid, laurocapram, Folium Ginkgo extract, Symwhite-337.
The present invention contains the whitening moisturizing face masque liquid of nostoc sphaeroids kutz extractive, preferably, its raw material comprises by weight: nostoc sphaeroids kutz extractive 0.03-0.2 part, wetting agent 9-10 part, NT-7WAN2-3 part, avenabeta glucosan 0.3-1 part, Radix Ampelopsis root extract 0.05 ~ 0.1 part, Rhizoma Atractylodis Macrocephalae rhizome extract 0.05 ~ 0.1 part, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.15 ~ 0.3 part, Radix Et Rhizoma Nardostachyos extract 0.25-5 part, Opuntia Streptacantha stem extract 0.1-0.2 part, Radix Ophiopogonis root extract 0.1-0.2 part, radix sophorae extract 0.1-0.2 part, chelating agen 0.02-0.05 part, solubilizing agent 0.1-0.2 part, antiseptic 0.1-1 part, thickening agent 0.1-0.4 part, essence 0.02-0.06 part, citric acid 0.001-0.1 part, water complements to 100 parts.
More preferably, its raw material comprises by weight: nostoc sphaeroids kutz extractive 0.1-0.2 part, wetting agent 10 parts, NT-7WAN3 part, avenabeta glucosan 0.5 part, Radix Ampelopsis root extract 0.05 ~ 0.1 part, Rhizoma Atractylodis Macrocephalae rhizome extract 0.05 ~ 0.1 part, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.15 ~ 0.3 part, Radix Et Rhizoma Nardostachyos extract 0.25-5 part, Opuntia Streptacantha stem extract 0.1-0.2 part, Radix Ophiopogonis root extract 0.1-0.2 part, radix sophorae extract 0.1-0.2 part, chelating agen 0.05 part, solubilizing agent 0.2 part, antiseptic 0.15-0.7 part, thickening agent 0.4 part, 0.06 part, essence, citric acid 0.002 part, water complements to 100 parts.
The preferred forms that the present invention contains the whitening moisturizing face masque liquid of nostoc sphaeroids kutz extractive is: its raw material comprises by weight: nostoc sphaeroids kutz extractive 0.2 part, wetting agent 10 parts, NT-7WAN3 part, avenabeta glucosan 0.5 part, Radix Ampelopsis root extract 0.1 part, Rhizoma Atractylodis Macrocephalae rhizome extract 0.1 part, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.3 part, Radix Et Rhizoma Nardostachyos extract 0.5 part, Opuntia Streptacantha stem extract 0.2 part, Radix Ophiopogonis root extract 0.2 part, radix sophorae extract 0.2 part, chelating agen 0.05 part, solubilizing agent 0.2 part, antiseptic 0.7 part, thickening agent 0.4 part, 0.06 part, essence, citric acid 0.002 part, water complements to 100 parts.
The present invention utilizes multiple whitening skin and preserving moisture composition from source, and restraint of tyrosinase generates, and free radical resisting, reduces melanic generation, isolate ultraviolet simultaneously; Promote containing the coming off of melanocyte additionally by the renewal speed accelerating Skin Cell.
Concrete, described nostoc sphaeroids kutz extractive is obtained through supercritical carbon dioxide extraction, distilling under reduced pressure, lyophilization by Nostoc.
More concrete, the preparation method of nostoc sphaeroids kutz extractive comprises the following steps:
(1) Nostoc after appropriate pulverizing is got, seal after loading the extraction column of supercritical carbon dioxide extraction system, extracting system is warming up to 48 ~ 50 DEG C respectively, boosts to 25 ~ 30MPa, start cycling extraction, and the flow velocity of regulation of carbon dioxide is 1 ~ 5L/min, keep constant temperature and pressure extraction 3.5 ~ 4h, be extracted thing;
(2) described extract is obtained nostoc sphaeroids kutz extractive after distilling under reduced pressure, lyophilization.
The nostoc sphaeroids kutz extractive yield utilizing said method to obtain is high, and free from environmental pollution in process, and can keep its biological activity to greatest extent.
Described Radix Ampelopsis root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Et Rhizoma Nardostachyos extract, Opuntia Streptacantha stem extract, Radix Ophiopogonis root extract, radix sophorae extract is from carrying.
Wherein the preparation method of Radix Ampelopsis root extract comprises the following steps:
(1) get the stripping and slicing of Radix Ampelopsis root or after pulverizing, add water swelling;
(2) the Radix Ampelopsis root after swelling is placed in hermetic container to pass to water vapour heat and steam, control steam pressure is 600 ~ 1000kPa, and temperature is 130 ~ 160 DEG C, and the time is 1.5 ~ 2.0h, collecting by filtration filtrate;
(3) described filtrate through concentrating under reduced pressure, precipitate with ethanol, centrifugal after be precipitated, dry described precipitation and namely obtain Radix Ampelopsis root extract.
Rhizoma Atractylodis Macrocephalae rhizome extract, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Et Rhizoma Nardostachyos extract, Opuntia Streptacantha stem extract, Radix Ophiopogonis root extract, radix sophorae extract preparation method identical with the preparation method of Radix Ampelopsis root extract, do not repeat them here.
In the inventive solutions, concrete, described wetting agent is selected from glycerol, propylene glycol, 1, one or more in 3 butanediols, Sorbitol, betanin, Lubrajel Oil, PEG-26 glycerin ether, carbamide, aminoacid, polypropylene glycols, monosaccharide or polysaccharide, are preferably one or more in glycerol, propylene glycol, butanediol, PEG-26 glycerin ether, glucose, betanin, aminoacid; Be more preferably butanediol, PEG-26 glycerin ether, aminoacid, betanin mass ratio be 3:4:2:1.
Described chelating agen is selected from one or more in EDETATE SODIUM, EDTA tetra-sodium or sodium citrate, is preferably EDETATE SODIUM.
Described solubilizing agent is selected from one or more in Cremophor RH40, PPG-26-butylol polyether-26 or tween 20, is preferably Cremophor RH40.
Described antiseptic is selected from parabens, Methylisothiazolinone, phenoxyethanol, benzyl alcohol, chlorphenesin, sorbic acid and salt thereof, benzoic acid and salt, Sensiva SC50, DMDM Hydantoin, imidazolidinyl urea, fragrant fresh ketone, decanediol, polyaminopropyl biguanide, 1, one or more in 2 ethohexadiols or iodine propilolic alcohol butyl mephenesin Carbamate, are preferably fragrant fresh ketone, hexanediol, chlorphenesin.
Described thickening agent is selected from one or more in carbomer, sodium polyacrylate, HANSHENGJIAO, hydroxyethyl-cellulose, Scleroglucan or Radix Acaciae senegalis, is preferably HANSHENGJIAO, hydroxyethyl-cellulose, Scleroglucan.
Invention further provides the preparation method of the described whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive, comprise the following steps:
(1) get chelating agen to be added to the water to be stirred to and to dissolve completely, then add thickening agent and wetting agent, be stirred to complete swelling, be heated to 75 ~ 80 DEG C of obtained component A;
(2) component A insulated and stirred is after 20 ~ 30 minutes, is cooled to 40 ~ 45 DEG C, successively nostoc sphaeroids kutz extractive, NT-7WAN, avenabeta glucosan, Radix Ampelopsis root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Et Rhizoma Nardostachyos extract, Opuntia Streptacantha stem extract, Radix Ophiopogonis root extract, radix sophorae extract, solubilizing agent, antiseptic, essence, citric acid, stirs, and to obtain final product.
Whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive provided by the invention can whitening skin and preserving moisture, increases skin elasticity, makes skin fine and smooth, smooth, glossy, and tested by antiallergic, whitening effect is remarkable, without any side effects, safe and reliable, can be used as facial film class skin-protection product life-time service.The preparation method of the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive provided by the invention, simple and effectively, and can production cost be reduced.
Detailed description of the invention
Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.The Radix Ampelopsis root extract adopted in an embodiment, Rhizoma Atractylodis Macrocephalae rhizome extract, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Et Rhizoma Nardostachyos extract, Opuntia Streptacantha stem extract, Radix Ophiopogonis root extract, radix sophorae extract is from carrying, and method is:
(1) get respectively Radix Ampelopsis root, Rhizoma Atractylodis Macrocephalae rhizome, Pseudobulbus Bletillae (Rhizoma Bletillae) root, Radix Et Rhizoma Nardostachyos, Opuntia Streptacantha stem, Radix Ophiopogonis root radix sophorae stripping and slicing or pulverize after, add water swelling;
(2) by the Radix Ampelopsis root after swelling, Rhizoma Atractylodis Macrocephalae rhizome, Pseudobulbus Bletillae (Rhizoma Bletillae) root, Radix Et Rhizoma Nardostachyos, Opuntia Streptacantha stem, Radix Ophiopogonis root or radix sophorae be placed in hermetic container and pass to water vapour heat and steam, control steam pressure is 600 ~ 1000kPa, temperature is 130 ~ 160 DEG C, time is 1.5 ~ 2.0h, collecting by filtration filtrate;
(3) described filtrate through concentrating under reduced pressure, precipitate with ethanol, centrifugal after be precipitated, dry described precipitation namely obtain respectively Radix Ampelopsis root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Et Rhizoma Nardostachyos extract, Opuntia Streptacantha stem extract, Radix Ophiopogonis root extract and radix sophorae extract.
Embodiment 1 ~ embodiment 5
The raw material of the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive in embodiment 1 ~ embodiment 5 is as shown in table 1.
The raw material (part) of table 1 embodiment 1 ~ 5 whitening moisturizing face masque liquid
Embodiment 6
The raw material that the present embodiment contains the whitening moisturizing face masque liquid of nostoc sphaeroids kutz extractive comprises by weight: nostoc sphaeroids kutz extractive 0.005 part, wetting agent 30 parts, NT-7WAN0.5 part, avenabeta glucosan 0.1 part, Radix Ampelopsis root extract 0.01 part, Rhizoma Atractylodis Macrocephalae rhizome extract 0.01 part, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.03 part, Radix Et Rhizoma Nardostachyos extract 0.05 part, Opuntia Streptacantha stem extract 0.01 part, Radix Ophiopogonis root extract 0.01 part, radix sophorae extract 0.01 part, chelating agen 0.01 part, solubilizing agent 0.01 part, antiseptic 0.01 part, thickening agent 0.01 part, 0.01 part, essence, citric acid 0.0001 part, water complements to 100 parts.
Wherein wetting agent, chelating agen, solubilizing agent, antiseptic, thickening agent can select all products described in summary of the invention part.
Embodiment 7
The raw material that the present embodiment contains the whitening moisturizing face masque liquid of nostoc sphaeroids kutz extractive comprises by weight: nostoc sphaeroids kutz extractive 2.0 parts, wetting agent 1 part, NT-7WAN10 part, avenabeta glucosan 5 parts, Radix Ampelopsis root extract 1 part, Rhizoma Atractylodis Macrocephalae rhizome extract 1 part, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 3 parts, Radix Et Rhizoma Nardostachyos extract 5 parts, Opuntia Streptacantha stem extract 1 part, Radix Ophiopogonis root extract 1 part, radix sophorae extract 1 part, chelating agen 0.3 part, solubilizing agent 1 part, antiseptic 1 part, thickening agent 1 part, 1 part, essence, citric acid 0.1 part, water complements to 100 parts.
Wherein wetting agent, chelating agen, solubilizing agent, antiseptic, thickening agent can select all products described in summary of the invention part.
Embodiment 8
Originally be embodied as the preparation method of the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive described in embodiment 1 ~ 7, specifically comprise the following steps:
(1) get chelating agen and add deionized water for stirring to dissolving completely, add thickening agent and wetting agent, be stirred to complete swelling, be heated to 75 ~ 80 DEG C of obtained component A;
(2) insulated and stirred is after 20 ~ 30 minutes, is cooled to 40 ~ 45 DEG C, adds nostoc sphaeroids kutz extractive successively, NT-7WAN, avenabeta glucosan, Radix Ampelopsis root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Et Rhizoma Nardostachyos extract, Opuntia Streptacantha stem extract, Radix Ophiopogonis root extract, radix sophorae extract, solubilizing agent, antiseptic, essence, citric acid, stirs, and gets product to 38 DEG C of fills that are up to the standards.
Embodiment 9
Originally be embodied as the preparation method of nostoc sphaeroids kutz extractive in embodiment 1 ~ 7, specifically comprise the following steps:
(1) Nostoc after appropriate pulverizing is got, seal after loading the extraction column of supercritical carbon dioxide extraction system, extracting system is warming up to 50 DEG C respectively, boosts to 30MPa, start cycling extraction, and the flow velocity of regulation of carbon dioxide is 1 ~ 5ml/min, keep constant temperature and pressure extraction 4h, be extracted thing;
(2) described extract is obtained nostoc sphaeroids kutz extractive after distilling under reduced pressure, lyophilization.
Experimental example 1: skin irritation test
The whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive of the embodiment of the present invention 1 ~ 5 is carried out repeatedly (acute) Skin Irritation Test, and concrete, experimental condition is: laboratory temperature 20-24 DEG C of relative humidity 60-70%; Experimental animal is: Cavia porcellus (female/male), and body weight is 250 ~ 300g; Test method is carried out with reference to " cosmetics health specification " 2007 editions.Finally obtain statistical data as shown in table 2:
Table 2 many (acute) Skin Irritation Test results
The result of embodiment 2,3,4,5 is all identical with embodiment 1, does not repeat them here.
As from the foregoing, this product is completely non-stimulated to skin.
Experimental example 2: restraint of tyrosinase activity experiment
The color of human skin is relevant with quantity with the kind of pigment existed in skin, and wherein melanin has the greatest impact to skin color, and in melanic forming process, tryrosinase is the most key, and restraint of tyrosinase activity can play the effect of whitening.
Restraint of tyrosinase activity experiment concrete steps are as follows:
(wherein in A1, A2, distilled water is added by table 3 with micropipettor, testing sample is added in B1, B2) accurately draw A1, A2, B1, B2 tetra-groups of sample liquids, be placed in 37 DEG C of water-bath constant temperature 10 minutes, then 0.3ml tyrosinase solution is respectively added, react after 5 minutes, in rapid immigration cuvette, ultraviolet-spectrophotometer is used to survey absorbance (hereinafter referred to as OD) at 475nm place.
Wherein, described testing sample is prepare whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive according to the raw material of embodiment 1-5.
Respectively by A1, A2, B1, B2 tetra-OD value list of group reaction liquid, ask tyrosinase inhibition rate by following formula.
Suppression ratio=[1-(B2-B1)/(A2-A1)] × 100%
Wherein A2-A1 is the change in the OD value not having the reactant liquor under inhibitor condition, and B2-B1 is having the OD value of the reactant liquor under inhibitor condition.
The mensuration reagent dosage table (ml) of table 3 tyrosinase inhibitory action
Note: band * is the amount of distilled water, and sample is the facial mask liquid of embodiment 1 ~ 5;
Phosphate buffer pH=6.8;
TYR solution concentration=0.512mg/ml.
After the whitening moisturizing face masque liquid prepared by raw material according to embodiment 1-5 containing nostoc sphaeroids kutz extractive is tested according to above-mentioned experimental procedure respectively, obtain preparing the inhibitory action result of the whitening moisturizing face masque containing nostoc sphaeroids kutz extractive to tryrosinase, in table 4 according to the raw material of embodiment 1-5.
Table 4 embodiment 1-5 is to tyrosinase inhibitory action result
From the data in upper table, embodiment 1-5 is all inhibited to tryrosinase, and wherein the suppression ratio of embodiment 2,4 and 5 all can reach more than 77%, and the inhibitory action of embodiment 5 is the strongest, and stronger to the inhibitory action of tryrosinase, whitening effect is better.
Experimental example 3: human test
Choose the healthy Asia women of 20 ages between 18-46 year as volunteer, comprise various types of skin 20 volunteers.One side face of volunteer uses facial film (the whitening moisturizing face masque liquid containing embodiment 1 ~ 5) every night, and another side face does not use any product, continues to stop using after 1 month.After first time uses, volunteer's reaction of 80%, whiteness of skin, continue use after one month, the subject perception skin of 100% has obvious whitening, and does not crack down upon evil forces after stopping using, and does not rely on.
Experimental example 4: moisture-keeping functions is tested
Carry out moisture-keeping functions experiment to the whitening moisturizing face masque that the formula according to embodiment 1-5 prepares, wherein experimenter, instrument and equipment, experimental technique, statistical method are all identical with the embodiment 9 of CN101822630A, and experimental result is as described in Table 5.
The moisture saver mask of the whitening moisturizing face masque of the present embodiment 1-5 and the embodiment 5 of CN101822630A, dosage form is different, the whitening moisturizing face masque of the present embodiment 1-5 is liquid SMD facial film (nostoc sphaeroids kutz extractive wherein added is only 2% at most), and the moisture saver mask of the embodiment 5 of CN101822630A is cream frost shape smearing mask (nostoc sphaeroids kutz extractive wherein added is 14.32%), both are two dissimilar products, using method is also different, so the application only with blank as a comparison case.
The skin moisture content value of each time point of table 5
| Time point | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Blank |
| Basis | 35.28±6.45 | 35.28±6.45 | 35.28±6.45 | 36.12±6.21 | 35.28±6.45 | 36.00±6.62 |
| 30 minutes | 66.54±9.09 | 65.38±8.84 | 66.46±9.11 | 66.69±8.45 | 68.34±9.47 | 35.79±6.33 |
| 1 hour | 65.91±8.43 | 65.86±8.18 | 65.21±8.65 | 66.45±8.23 | 67.54±8.78 | 36.04±6.32 |
| 2 hours | 60.65±8.22 | 61.87±8.22 | 61.27±8.28 | 64.72±8.35 | 66.27±8.45 | 35.56±6.05 |
| 4 hours | 55.45±7.98 | 57.28±8.34 | 56.91±7.99 | 57.78±8.71 | 60.28±8.98 | 37.18±6.59 |
| 6 hours | 50.53±8.13 | 55.48±8.12 | 53.48±7.87 | 55.21±7.98 | 58.48±8.26 | 36.44±6.56 |
As can be seen from the data in upper table, the embodiment of the present application 1-5 smears latter 30 minutes, 1 hour, 2 hours, 4 hours and all has remarkable moistening effect in 6 hours, and after smearing 2 hours, the effect of embodiment 2,4 and 5 is better, be wherein the best with embodiment 5.And embodiment 1-5 did not all cause experimenter to occur the skin adverse reactions such as erythema, edema, welt in 6 hours.
Because length limit, although the application only lists the effect data of 5 embodiments, the facial mask liquid obtained according to the application's other technologies scheme all can play the effect of whitening skin and preserving moisture, and completely non-stimulated to skin.The user that the present invention adopts nostoc sphaeroids kutz extractive to be applicable to all skin quality with the other materials whitening moisturizing face masque liquid carried out obtained by effective proportioning uses, and has obvious whitening function, and product itself does not have toxicity, environmentally safe.Various raw material of the present invention is easily purchased, is easily made, with low cost, and the manufacture method of product simply, is easily grasped, qualification rate is high, and the environment, the equipment requirements that make needs are low.The present invention is that Nostoc provides more effective economic benefit source, achieves the multipath comprehensive utilization of Nostoc, makes the economic benefit of Nostoc, social benefit, environmental benefit reach maximization.
Although above the present invention is described in detail with a general description of the specific embodiments, on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (10)
1. the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive, it is characterized in that, its raw material comprises by weight: nostoc sphaeroids kutz extractive 0.005-2.0 part, wetting agent 1-30 part, NT-7WAN0.5-10 part, avenabeta glucosan 0.1-5 part, Radix Ampelopsis root extract 0.01-1 part, Rhizoma Atractylodis Macrocephalae rhizome extract 0.01-1 part, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.03-3 part, Radix Et Rhizoma Nardostachyos extract 0.05-5 part, Opuntia Streptacantha stem extract 0.01-1 part, Radix Ophiopogonis root extract 0.01-1 part, radix sophorae extract 0.01-1 part, chelating agen 0.01-0.3 part, solubilizing agent 0.01-1 part, antiseptic 0.01-1 part, thickening agent 0.01-1 part, essence 0.01-1 part, citric acid 0.0001-0.1 part, water complements to 100 parts.
2. the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive according to claim 1, it is characterized in that, its raw material comprises by weight: nostoc sphaeroids kutz extractive 0.03-0.2 part, wetting agent 9-10 part, NT-7WAN2-3 part, avenabeta glucosan 0.3-1 part, Radix Ampelopsis root extract 0.05 ~ 0.1 part, Rhizoma Atractylodis Macrocephalae rhizome extract 0.05 ~ 0.1 part, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.15 ~ 0.3 part, Radix Et Rhizoma Nardostachyos extract 0.25-5 part, Opuntia Streptacantha stem extract 0.1-0.2 part, Radix Ophiopogonis root extract 0.1-0.2 part, radix sophorae extract 0.1-0.2 part, chelating agen 0.02-0.05 part, solubilizing agent 0.1-0.2 part, antiseptic 0.1-1 part, thickening agent 0.1-0.4 part, essence 0.02-0.06 part, citric acid 0.001-0.1 part, water complements to 100 parts.
3. the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive according to claim 2, it is characterized in that, its raw material comprises by weight: nostoc sphaeroids kutz extractive 0.2 part, wetting agent 10 parts, NT-7WAN3 part, avenabeta glucosan 0.5 part, Radix Ampelopsis root extract 0.1 part
Rhizoma Atractylodis Macrocephalae rhizome extract 0.1 part, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.3 part, Radix Et Rhizoma Nardostachyos extract 0.5 part,
Opuntia Streptacantha stem extract 0.2 part, Radix Ophiopogonis root extract 0.2 part, radix sophorae extract 0.2 part, chelating agen 0.05 part, solubilizing agent 0.2 part, antiseptic 0.7 part, thickening agent 0.4 part, 0.06 part, essence, citric acid 0.002 part, water complements to 100 parts.
4. the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive according to any one of claims 1 to 3, it is characterized in that, described wetting agent is selected from glycerol, propylene glycol, 1, one or more in 3 butanediols, Sorbitol, betanin, Lubrajel Oil, PEG-26 glycerin ether, carbamide, aminoacid, polypropylene glycols, monosaccharide or polysaccharide.
5. the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive according to any one of claims 1 to 3, it is characterized in that, described chelating agen is selected from one or more in EDETATE SODIUM, EDTA tetra-sodium or sodium citrate.
6. the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive according to any one of claims 1 to 3, it is characterized in that, described solubilizing agent is selected from one or more in Cremophor RH40, PPG-26-butylol polyether-26 or tween 20.
7. the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive according to any one of claims 1 to 3, it is characterized in that, described antiseptic is selected from parabens, Methylisothiazolinone, phenoxyethanol, benzyl alcohol, chlorphenesin, sorbic acid and salt thereof, benzoic acid and salt, Sensiva SC50, DMDM Hydantoin, imidazolidinyl urea, fragrant fresh ketone, decanediol, polyaminopropyl biguanide, 1, one or more in 2 ethohexadiols or iodine propilolic alcohol butyl mephenesin Carbamate.
8. the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive according to any one of claims 1 to 3, it is characterized in that, described thickening agent is selected from one or more in carbomer, sodium polyacrylate, HANSHENGJIAO, hydroxyethyl-cellulose, Scleroglucan or Radix Acaciae senegalis.
9. the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive according to any one of claims 1 to 3, it is characterized in that, described nostoc sphaeroids kutz extractive is obtained through supercritical carbon dioxide extraction, distilling under reduced pressure, lyophilization by Nostoc.
10. the preparation method of the whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive described in any one of claim 1 ~ 9, is characterized in that, comprise the following steps:
(1) get chelating agen to be added to the water to be stirred to and to dissolve completely, then add thickening agent and wetting agent, be stirred to complete swelling, be heated to 75 ~ 80 DEG C of obtained component A;
(2) component A insulated and stirred is after 20 ~ 30 minutes, is cooled to 40 ~ 45 DEG C, adds nostoc sphaeroids kutz extractive successively, NT-7WAN, avenabeta glucosan, Radix Ampelopsis root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Et Rhizoma Nardostachyos extract, Opuntia Streptacantha stem extract, Radix Ophiopogonis root extract, radix sophorae extract, solubilizing agent, antiseptic, essence, citric acid, stirs, and to obtain final product.
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| CN106214531A (en) * | 2016-07-25 | 2016-12-14 | 湖北艾源蕲艾科技有限公司 | A kind of Artemisia argyi Levl. et Van. var. argyi cv. Qiai bacteriostasis spray |
| CN106333888A (en) * | 2016-08-24 | 2017-01-18 | 登封市科创商务咨询有限公司 | Anti-inflammatory facial cleanser with nostoc sphaeroids kutz |
| CN106344420B (en) * | 2016-09-29 | 2019-01-29 | 常德炎帝生物科技有限公司 | A kind of nostoc Multifunctional cotton and the preparation method and application thereof |
| CN106344420A (en) * | 2016-09-29 | 2017-01-25 | 常德炎帝生物科技有限公司 | Multifunctional common nostoc cotton as well as preparation method and application thereof |
| CN106798698A (en) * | 2017-03-03 | 2017-06-06 | 北京华奥光程化妆品有限公司 | A kind of plant extracts of skin moisture-keeping desalination microgroove and its preparation method and application |
| CN106798698B (en) * | 2017-03-03 | 2020-05-19 | 北京华奥光程化妆品有限公司 | Plant extract for moisturizing skin and reducing fine wrinkles as well as preparation method and application thereof |
| CN107137250A (en) * | 2017-05-12 | 2017-09-08 | 广州娇漾生物科技有限公司 | A kind of moisturizing anti-ageing face mask containing carboxymethylpachymaran |
| CN107625680A (en) * | 2017-09-26 | 2018-01-26 | 杭州梵琳科技有限公司 | Shu Min aquas and preparation method thereof |
| CN107625680B (en) * | 2017-09-26 | 2020-07-10 | 杭州梵琳科技有限公司 | Allergy-relieving water agent and preparation method thereof |
| CN110403201A (en) * | 2018-08-07 | 2019-11-05 | 湖南炎帝生物工程有限公司 | Nostoc composition and its application in raising skin collagen content and improvement skin elasticity and slackness |
| CN109805408A (en) * | 2019-04-01 | 2019-05-28 | 青岛浩然海洋科技有限公司 | A kind of nostoc capsule and preparation method thereof |
| CN110075048A (en) * | 2019-06-03 | 2019-08-02 | 王金会 | A kind of Chinese herbal medicine cosmetic and preparation method thereof |
| CN111529463A (en) * | 2020-05-15 | 2020-08-14 | 广州比力福生物科技有限公司 | Compound plant anti-allergy agent |
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