CN108324667A - Composition and anti-aging Skin whitening care cosmetics containing light black huge marine algae extract - Google Patents

Composition and anti-aging Skin whitening care cosmetics containing light black huge marine algae extract Download PDF

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CN108324667A
CN108324667A CN201810311061.8A CN201810311061A CN108324667A CN 108324667 A CN108324667 A CN 108324667A CN 201810311061 A CN201810311061 A CN 201810311061A CN 108324667 A CN108324667 A CN 108324667A
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parts
component
light black
marine algae
algae extract
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陈海佳
葛啸虎
王飞
王一飞
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
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  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a kind of composition containing light black huge marine algae extract and its applications.The above-mentioned composition containing light black huge marine algae extract, including the first component and the second component, and first component include the light black huge marine algae extract centainly matched, dogfish oil and Barley Greeg, second component includes the Hydrolyzed Collagen centainly matched and water soluble pearl albumen, the mutual cooperation of said components makes light black huge marine algae extract, dogfish oil, Barley Greeg and Hydrolyzed Collagen can play preferable cell repair and protective effect, and the oxidation for inhibiting free radical can be played, with preferable anti-aging effects, Hydrolyzed Collagen can promote the permeability of water soluble pearl albumen simultaneously, so that above-mentioned composition is with preferable white-skinned face function;In addition, the mutual cooperation of said components so that composition has preferable stability.

Description

Composition and anti-aging Skin whitening care cosmetics containing light black huge marine algae extract
Technical field
The present invention relates to daily chemical product technical fields, more particularly to the composition containing light black huge marine algae extract and resist Aging Skin whitening care cosmetics.
Background technology
With stepping up for people's living standard, more and more people focus more on U.S. face skin care, especially with The growth at age, people are also higher and higher for inhibiting the needs that skin aging keeps skin youth state.Skin aging it is main Performance is that phenomena such as wrinkle, drying, peeling and relaxation occur.And the main reason for making skin aging is photo-aging and freedom The peroxidation of base, therefore, most direct and common mode are to hinder photochemical reaction and free radical as being added in skin care item The chemical reagent or biological enzyme of peroxidation, then aforesaid way is although quick, but use for a long time can be to human body skin Skin damages, and the stability of product and anti-aging effects are insufficient.Meanwhile common anti-aging product is also difficult to have both whitening Effect.
Invention content
Based on this, it is necessary to for currently used skin-protection product stability and anti-aging performance deficiency, be difficult to have both U.S. The problem of white effect, provides a kind of composition and anti-aging Skin whitening care cosmetics containing light black huge marine algae extract.
A kind of composition containing light black huge marine algae extract, including the first component and the second component;
Wherein, first component includes according to the mass fraction:6 parts~10 parts of light black huge marine algae extract, 3 parts~6 The dogfish oil and 1~3 part of Barley Greeg of part;
Second component includes according to the mass fraction:4 parts~8 parts of Hydrolyzed Collagen and 1 part~3 parts of water-soluble treasure Globin;
The mass ratio of first component and second component is " 12~18 ":" 4~8 ".
In a wherein embodiment, according to the mass fraction, first component further includes that 3 parts~6 parts of Radix Angelicae Sinensis carries Take object, 2 parts~5 parts of mulberries extract and 1 part~3 parts of ursin.
In a wherein embodiment, according to the mass fraction, first component further includes that 3 parts~5 parts of Radix Angelicae Sinensis carries Take object, 3 parts~4 parts of mulberries extract and 2 parts~3 parts of ursin.
In a wherein embodiment, the composition containing light black huge marine algae extract further includes third component, The third component is selected from least one of water, propylene glycol and glycerine.
In a wherein embodiment, the mass ratio of first component and the third component is " 10~20 ":“10 ~100 ".
In a wherein embodiment, the mass ratio of first component and second component is " 15~17 ":“4 ~6 ".
A kind of anti-aging Skin whitening care cosmetics, including the above-mentioned composition containing light black huge marine algae extract.
In a wherein embodiment, the dosage form of the anti-aging Skin whitening care cosmetics is creme, lotion, aqua or face Film.
In a wherein embodiment, the composition containing light black huge marine algae extract is in the anti-aging whitening Mass percentage in skin care item is 0.6%~10%.
Above-mentioned composition and anti-aging Skin whitening care cosmetics containing light black huge marine algae extract, including the first component and second Component, and the first component includes light black huge marine algae extract, dogfish oil and the Barley Greeg centainly matched, the second component includes one Surely the mutual cooperation of the Hydrolyzed Collagen and water soluble pearl albumen matched, said components makes light black huge marine algae extract, shark Cod-liver oil, Barley Greeg and Hydrolyzed Collagen can play preferable cell repair and protective effect, and can play inhibition certainly By the oxidation of base, there are preferable anti-aging effects, while Hydrolyzed Collagen can promote oozing for water soluble pearl albumen Permeability so that above-mentioned composition is with preferable white-skinned face function;In addition, due to light black huge marine algae extract in above-mentioned composition In trehalose can form unique protective film in cell surface, to be effectively protected protein molecule invariance inactivation, And the stability of water soluble pearl albumen is inadequate, and light black huge marine algae extract is used in compounding with water soluble pearl albumen, can improve Water soluble pearl albumen is in the above-mentioned stability with the composition of pox-eliminating whitening, to reach better white-skinned face function.
Specific implementation mode
The composition containing light black huge marine algae extract and its application are done further below in conjunction with specific implementation mode Detailed description.
The composition containing light black huge marine algae extract of one embodiment includes the first component and the second component.
In a wherein embodiment, the first component includes according to the mass fraction:6 parts~10 parts of light black huge seaweed carries Take object, 3 parts~6 parts of dogfish oil, 1 part~3 parts of Barley Greeg, 3 parts~6 parts of angelica extract, 2 parts~5 parts of mulberries Extract and 1 part~3 parts of ursin.
In a wherein embodiment, according to the mass fraction, the dosage of light black huge marine algae extract is 6 parts~10 parts, Further, the dosage of light black huge marine algae extract can also be 7 parts, 7.5 parts, 8 parts, 8.5 parts and 9 parts.
In a wherein embodiment, the method for preparing light black huge marine algae extract includes the following steps:
(1) light black huge seaweed is freeze-dried, the temperature being freeze-dried is -15 DEG C~-5 DEG C, is freezed The dry time is 2h~3h.
(2) it will be crushed by the light black huge seaweed of freeze-drying.
(3) in the mixed solvent of water and ethyl alcohol will be scattered in by the light black huge seaweed crushed, and at 75 DEG C~85 DEG C Carry out refluxing extraction;Wherein, the volume ratio of ethyl alcohol and water is 3:1~4:1, time of refluxing extraction is 12h~for 24 hours.
(4) extracting solution is filtered filtrate, filtrate is subjected to reduction vaporization concentration.
(5) it will be dried to obtain light black huge marine algae extract by the extracting solution that concentration is evaporated under reduced pressure.
Light black huge seaweed belongs to one kind in deep sea algae, and containing abundant trehalose, trehalose has mystery to organism Protective effect, be because trehalose under the severe environmental conditions such as high temperature, high and cold, hyperosmosis and dry dehydration in cell table Face can form unique protective film, protein molecule invariance inactivation is effectively protected, to the life process for the body that sustains life And biological characteristic.Many species that extraneous adverse circumstances are shown with outstanding degeneration-resistant tolerance all exist with them a large amount of in vivo Trehalose have a direct relationship, and such as other carbohydrates of sucrose, glucose in nature do not have this function.This Unique functional characteristic so that trehalose is in addition to that can be used as pharmaceutical grade protein, enzyme, vaccine and the excellent work of other biological product Other than property protective agent, it is also to maintain cell activity, the important component of moisturizing class cosmetics.
In addition, skin is a water storage library of human body, institute's water content accounts for about the 18%~20% of weight.Skin is moistened There is close relationship with elasticity and the moisture in skin, when the moisture in skin is excessively lost, can cause to have dry skin, even Chap.Seaweed is a kind of excellent emollient, and the active material being not only because in seaweed can be combined to form guarantor with skin protein Moist gel, and it can also form protective film by aquation in skin surface, prevents moisture evaporation, and seaweed In the moistening effect of light black huge marine algae extract be also very outstanding.
In a wherein embodiment, according to the mass fraction, the dosage of dogfish oil can also be 4 parts, 4.5 parts and 5 Part.Dogfish oil extracts from the liver of deepwater shark, main component be spiny dogfish, hydrocarbon pacify glycerine, eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA), alkoxyglycerol (AKGS), vitamin A and vitamin E, dogfish oil can be supplemented to cell The effects that nutrient boosts metabolism, reparative regeneration, while having promotion immunity, radioresistance anticancer;In addition, dogfish oil Hemostasis and repair very good to the effect of exanthemv, also very strong;Its alkoxyglycerol contained has to anti-oxidant Unique effect.Although traditional antioxidant such as injection Vitamin B_6 also can be anti-oxidant, carried out from extracellular, Ji Shaoneng Penetration cell film, into having an effect into the cell, alkoxyglycerol is exactly one of cellular antioxidant few in number.
In a wherein embodiment, according to the mass fraction, the dosage of Barley Greeg can also be 1.5 parts, 2 parts and 2.5 Part.Barley Greeg powder contain abundant antioxidants, the superoxide dismutase (SOD enzymes) of unusual content, vitamin C, Vitamin E, β-carrotene, also contain 70 several mineral materials, plant flavone, catalase etc., and Barley Greeg can potent degradation Free radical, delaying cell aging promote organ dysfunction rejuvenation, to improve the vigor of body.
The above-mentioned composition containing light black huge marine algae extract includes the light black huge marine algae extract centainly matched, shark Cod-liver oil and Barley Greeg, three cooperate, and have certain synergistic effect so that above-mentioned composition has on skin anti-aging Preferable effect, especially light black huge marine algae extract can promote the maintenance effect of dogfish oil and Barley Greeg to skin, and Protective film is formed in maintenance cell surface so that above-mentioned composition senile-resistant efficacy is more lasting.
In a wherein embodiment, according to the mass fraction, the dosage of angelica extract can also be 3.5 parts, 4 parts, 4.5 parts and 5 parts.Radix Angelicae Sinensis is Umbelliferae herbaceos perennial, is used as medicine with root, is one of most common Chinese medicine.Its is warm-natured, taste It is sweet, pungent.Return liver, the heart, the spleen channel.With enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation and other effects, for blood deficiency chlorosis, the dizziness heart Throb with fear, the diseases such as irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, dry constipation of intestines, arthralgia pain due to rheumatism, injury from falling down, ulcer sores.In addition, existing It is confirmed for medical research, the main component of Radix Angelicae Sinensis is a variety of organic acids, lipid, sugar, a variety of amino acid, trace element and other More than the totally 80 kinds of chemical substance such as organic principle has good beauty functions.Ferulic acid be Radix Angelicae Sinensis antioxidation it is effective at Point, by directly eliminating free radical, inhibit membrane lipid peroxidatio reaction and radical reaction, Yi Jiyu caused by superoxide radical Damage of a variety of mechanism antagonism free radicals such as biological film phospholipid join protection membrane lipid to tissue, to the face caused by free radical retardance Color is gloomy, not magnificent and life sore swells have special efficacy.Radix Angelicae Sinensis contains 17 kinds of amino acid, wherein 7 kinds of threonine, leucine etc. for human body not Can synthesis and essential amino acid, if lacking it, skin if, seems coarse more wrinkles.Potassium, sodium, calcium, magnesium contained by Radix Angelicae Sinensis, 23 kinds of inorganic salts such as zinc, selenium are adjusted the metabolism of human body, prevent dermopathic generation.The vitamin A that contains in Radix Angelicae Sinensis, Vitamin B12, vitamin E etc. have substantial connection with beauty.Since Radix Angelicae Sinensis can expand scalp capillary, promotion blood follows Ring, and contain abundant trace element.
In a wherein embodiment, according to the mass fraction, the dosage of mulberries extract can also be 3.5 parts, 4 parts or 4.5 part.Mulberries have improvement skin blood supply, and nutrition skin keeps skin delicate, and can slow down aging, and is U.S. face, anti-aging Good medicine, and containing abundant activated protein, vitamin, amino acid, malic acid, carrotene, minerals, nutrition is apple 5-6 times, be 4 times of grape, has multiple efficacies.In addition, it is noted that mulberries extract is to preventing or inhibiting because of junket ammonia Sour enzyme effect and generate melanin, promote skin whitening on also have preferable effect.
In a wherein embodiment, according to the mass fraction, the dosage of ursin can also be 1.7 parts, 2.2 parts and 2.5 part.Further, ursin is alpha-arbutin, and compared to other ursin (such as β-ursin), alpha-arbutin is safer And stabilization.Alpha-arbutin plays the active work for inhibiting TYR enzyme in cosmetic industry often as white-skinned face function ingredient With, however, the osmotic energy force difference of alpha-arbutin, the whitening effect played is insufficient, generally requires to be used cooperatively with other compositions, when Return extract and mulberries extract that can promote the osmosis of alpha-arbutin, to preferably play the effect of whitening.
For current anti-aging product, it tends to be difficult to have both the effect of whitening, and angelica extract, mulberries extract and Being used cooperatively for ursin not only makes above-mentioned composition have preferable senile-resistant efficacy, and can be with preferable U.S. White effect, and angelica extract, mulberries extract and ursin are natural plant extracts, will not be produced to the skin of human body The compounding of raw damage, above-mentioned three kinds of components is used for the above-mentioned composition containing light black huge marine algae extract, can keep composition Preferable stability.
It should be noted that in other embodiments, the angelica extract, mulberries extract in the first component and black bearberry Glycosides can also omit.
In a wherein embodiment, the second component according to the mass fraction include 4 parts~8 parts Hydrolyzed Collagen and 1 part~3 parts of water soluble pearl albumen.
In a wherein embodiment, according to the mass fraction, the dosage of Hydrolyzed Collagen can also be 5 parts, 5.5 Part, 6 parts, 7 parts and 7.5 parts.Hydrolyzed Collagen can enhance the water holding effect of skin, and skin is made to have more permeability, and energy The content of skin collagen is enough promoted, meanwhile, also have and promotes skin metabolism, accelerating wound healing, delaying skin aging Effect.
In a wherein embodiment, according to the mass fraction, the dosage of water soluble pearl albumen can also be 1.5 parts, 2 parts With 2.5 parts.In a wherein embodiment, the preparation method of water-soluble pearl albumen is:Pearl is ground into pearl first The grain size of powder, further pearl powder is 10nm~100nm;Pearl powder is dispersed in water again to obtain dispersion liquid, and at 40 DEG C Homogenization processing is carried out at~60 DEG C, the time of processing is 30min~60min;By dispersion liquid be cooled to 5 DEG C~10 DEG C it is laggard Row centrifuges and obtains supernatant liquor;Supernatant liquor is placed in bag filter again and carries out dialysis and carried out desalting processing in 3 days~5 days to obtain To water-soluble pearl protein liquid;Water-soluble pearl protein liquid is dried and can be obtained water-soluble pearl protein powder.
Rich in there is the pearl composite whitening factor in water soluble pearl albumen, above-mentioned contain is added in the form of water soluble pearl albumen When having in the composition of light black huge marine algae extract, preferable stability can be kept, to play whitening effect, in addition, water Solving collagen has preferable hydrophily, water soluble pearl albumen can be promoted in the permeability of skin surface so that water-soluble treasure Globin plays better white-skinned face function.
In a wherein embodiment, the mass ratio of the first component and the second component is " 12~18 ":" 4~8 ", into one Step, the mass ratio of the first component and the second component can also be " 15~17 ":" 4~6 ".Further, the first component and the The mass ratio of two components can also be 16:5、13:6 or 12:6.
Above-mentioned composition and anti-aging Skin whitening care cosmetics containing light black huge marine algae extract, including the first component and second Component, and the first component includes light black huge marine algae extract, dogfish oil and the Barley Greeg centainly matched, the second component includes one Surely the mutual cooperation of the Hydrolyzed Collagen and water soluble pearl albumen matched, said components makes light black huge marine algae extract, shark Cod-liver oil, Barley Greeg and Hydrolyzed Collagen can play preferable cell repair and protective effect, and can play inhibition certainly By the oxidation of base, there are preferable anti-aging effects, while Hydrolyzed Collagen can promote oozing for water soluble pearl albumen Permeability so that above-mentioned composition is with preferable white-skinned face function;In addition, due to light black huge marine algae extract in above-mentioned composition In trehalose can form unique protective film in cell surface, to be effectively protected protein molecule invariance inactivation, And the stability of water soluble pearl albumen is poor, and light black huge marine algae extract is used in compounding with water soluble pearl albumen, can improve water Molten pearl protein is in the above-mentioned stability with the composition of pox-eliminating whitening, to reach better white-skinned face function.
In addition, after being equipped with the angelica extract suitably matched, mulberries extract and ursin in above-mentioned composition, Neng Gouti For better electrolyte environment, and there is good compatibility, the adhesion strength of corneocyte can be reduced, assists skin anti-inflammatory, It releives and promotes cell repair, accelerate epidermal cell update, promote skin fat metabolism, to reach the effect of better anti-aging Fruit;At the same time, the angelica extract suitably matched, mulberries extract and ursin are increased to and is extracted containing light black huge seaweed When in the composition of object, mutual facilitation can be played, and promotes the osmotic effect of each component in skin, it can be into one Step improves the anti-aging and white-skinned face function of composition.
It should be noted that in other embodiments, the above-mentioned composition containing light black huge marine algae extract further includes Third component.Third component is selected from least one of water, propylene glycol and glycerine, and third component is used mainly as a kind of solvent In the above-mentioned concentration containing light black huge marine algae extract of dilution so that the above-mentioned composition containing light black huge marine algae extract is applicable in In more products.
In a wherein embodiment, the mass ratio of the first component and third component is " 10~20 ":" 10~100 ", Further, the mass ratio of the first component and third component can also be " 12~18 ":" 40~70 ", further, first group The mass ratio with third component is divided to can also be 13:50、15:50、15:60 and 17:65 etc..
A kind of anti-aging Skin whitening care cosmetics, including the above-mentioned composition containing light black huge marine algae extract.
Further, the dosage form of above-mentioned anti-aging Skin whitening care cosmetics is creme, lotion, aqua or facial mask.
Further, the quality percentage of the composition of light black huge marine algae extract is contained in above-mentioned anti-aging Skin whitening care cosmetics Content is 0.6wt%~10wt%.
A kind of anti-aging active white skin care solution, including shin moisturizer matrix and the above-mentioned combination containing light black huge marine algae extract Object, wherein the mass percentage of the composition containing light black huge marine algae extract is 1wt%~5wt%.
In a wherein embodiment, above-mentioned shin moisturizer matrix includes according to the mass fraction:3 parts of isopropyl palmitate ~8 parts, 0.2 part~0.6 part of tocopherol acetate, 6 parts~12 parts of butanediol, 6 parts~12 parts of glycerine, PEG-60 rilanit specials 0.2 part~0.4 part and 75 parts~90 parts of water.
A kind of anti-aging whitening hand cream, including hand lotion matrix and the above-mentioned composition containing light black bulk kelp extract, Wherein, the mass percentage of the composition containing light black huge marine algae extract is 4wt%~10wt%.
In a wherein embodiment, above-mentioned hand lotion matrix includes according to the mass fraction:Evening primrose oil 5 parts~8 Part, 3 parts~6 parts of ethylhexyl palmitate, 1 part~5 parts of cetanol ethylhexoate, 1 part~5 parts of emulsifier, glycerine 6 parts~10 50 parts~65 parts of part and water.
A kind of anti-aging whitening mask, including mask matrix and the above-mentioned composition containing light black huge marine algae extract, In, the mass percentage of the composition containing light black huge marine algae extract is 1wt%~3wt%.
In a wherein embodiment, above-mentioned mask matrix includes according to the mass fraction:Isopropyl palmitate 3 parts~8 Part, 0.2 part~0.6 part of tocopherol acetate, 6 parts~12 parts of butanediol, 6 parts~12 parts of glycerine, PEG-60 rilanit specials 0.2 Part~0.4 part and 75 parts~90 parts of water.
It is the explanation of specific embodiment below, following embodiment unless otherwise specified, is not then contained except inevitably miscellaneous The component pointed out is not known in other other than matter.
Embodiment 1
A kind of composition containing light black huge marine algae extract includes the first component and the second component, wherein the first component Include according to the mass fraction:6 parts of light black huge marine algae extract, 6 parts of dogfish oil, 3 parts of Barley Greeg, 3 parts of Radix Angelicae Sinensis carry Take object, 2 parts of mulberries extract and 3 parts of ursin;Second component includes according to the mass fraction:8 parts of Hydrolyzed Collagen And 1 part of water soluble pearl albumen;And first the mass ratio of component and the second component be 12:4.
Embodiment 2
A kind of composition containing light black huge marine algae extract includes the first component and the second component, wherein the first component Include according to the mass fraction:10 parts of light black huge marine algae extract, 3 parts of dogfish oil, 1 part of Barley Greeg, 6 parts of Radix Angelicae Sinensis carry Take object, 5 parts of mulberries extract and 1 part of ursin;Second component includes according to the mass fraction:4 parts of Hydrolyzed Collagen And 3 parts of water soluble pearl albumen;And first the mass ratio of component and the second component be 13:6.
Embodiment 3
A kind of composition containing light black huge marine algae extract includes the first component and the second component, wherein the first component Include according to the mass fraction:8 parts of light black huge marine algae extract, 4 parts of dogfish oil, 2 parts of Barley Greeg, 5 parts of Radix Angelicae Sinensis carry Take object, 4 parts of mulberries extract and 2 parts of ursin;Second component includes according to the mass fraction:6 parts of Hydrolyzed Collagen And 2 parts of water soluble pearl albumen;And first the mass ratio of component and the second component be 12:6.
Embodiment 4
A kind of composition containing light black huge marine algae extract includes the first component and the second component, wherein the first component Include according to the mass fraction:7 parts of light black huge marine algae extract, 4.5 parts of dogfish oil, 2 parts of Barley Greeg, 4 parts of Radix Angelicae Sinensis Extract, 3.5 parts of mulberries extract and 2.2 parts of ursin;Second component includes according to the mass fraction:7 parts of hydrolysis glue Former albumen and 2.5 parts of water soluble pearl albumen;And first the mass ratio of component and the second component be 16:5.
Embodiment 5
A kind of composition containing light black huge marine algae extract includes the first component and the second component, wherein the first component Include according to the mass fraction:9 parts of light black huge marine algae extract, 4 parts of dogfish oil, 2 parts of Barley Greeg, 4 parts of Radix Angelicae Sinensis carry Take object, 4.5 parts of mulberries extract and 2.5 parts of ursin;Second component includes according to the mass fraction:5.5 parts of hydrolysis glue Former albumen and 2.5 parts of water soluble pearl albumen;And first the mass ratio of component and the second component be 15:4.
Embodiment 6
A kind of composition containing light black huge marine algae extract includes the first component and the second component, wherein the first component Include according to the mass fraction:7.5 parts of light black huge marine algae extract, 5 parts of dogfish oil, 2 parts of Barley Greeg, 4.5 parts work as Return extract, 4 parts of mulberries extract and 1.7 parts of ursin;Second component includes according to the mass fraction:7.5 parts of hydrolysis Collagen and 2 parts of water soluble pearl albumen;And first the mass ratio of component and the second component be 18:8.
Embodiment 7
A kind of composition containing light black huge marine algae extract includes the first component and the second component, wherein the first component Include according to the mass fraction:7 parts of light black huge marine algae extract, 4.5 parts of dogfish oil and 2 parts of Barley Greeg;Second component Include according to the mass fraction:7 parts of Hydrolyzed Collagen and 2.5 parts of water soluble pearl albumen;And first component and the second component Mass ratio be 16:5.
Embodiment 8
A kind of composition containing light black huge marine algae extract includes the first component and the second component, wherein the first component Include according to the mass fraction:7 parts of light black huge marine algae extract and 2 parts of Barley Greeg;Second component includes according to the mass fraction: 7 parts of Hydrolyzed Collagen and 2.5 parts of water soluble pearl albumen;And first the mass ratio of component and the second component be 16:5.
Embodiment 9
A kind of composition includes the first component and the second component, wherein the first component includes according to the mass fraction:7 parts Nicotinamide mononucleotide, 4.5 parts of dogfish oil and 2 parts of Barley Greeg;Second component includes according to the mass fraction:7 parts of water Solve collagen and 2.5 parts of water soluble pearl albumen;And first the mass ratio of component and the second component be 16:5.
Embodiment 10
A kind of composition includes the first component and the second component, wherein the first component includes according to the mass fraction:11.5 parts Dogfish oil and 2 parts of Barley Greeg;Second component includes according to the mass fraction:7 parts of Hydrolyzed Collagen and 2.5 parts of water Molten pearl protein;And first the mass ratio of component and the second component be 16:5.
Embodiment 11
A kind of composition containing light black huge marine algae extract includes the first component and the second component, wherein the first component Include according to the mass fraction:7 parts of light black huge marine algae extract, 4.5 parts of dogfish oil and 2 parts of Barley Greeg;Second component Include according to the mass fraction:7 parts of Hydrolyzed Collagen;And first the mass ratio of component and the second component be 16:5.
The composition containing light black huge marine algae extract of 100g embodiments 1~11 is taken respectively, in sealed states, is placed It is preserved in 25 DEG C of insulating box, stores 360 days, record the stabilization disposition of the above-mentioned composition containing light black huge marine algae extract Condition, the results are shown in Table 1.It refers to composition under above-mentioned condition of storage wherein to have good stability, do not occur layering, discoloration, Phenomena such as agglomerating or be rotten.
Table 1
Stability
Embodiment 1 Well
Embodiment 2 Well
Embodiment 3 Well
Embodiment 4 Well
Embodiment 5 Well
Embodiment 6 Well
Embodiment 7 Well
Embodiment 8 Well
Embodiment 9 The phenomenon that storage is turned to be yellow after 180 days
Embodiment 10 The phenomenon that storage is turned to be yellow after 180 days
Embodiment 11 Well
It is seen from the above data that it is above-mentioned containing the composition of light black huge marine algae extract in light black huge seaweed is added Have the function of stablizing composition after extract so that above-mentioned composition has preferable stability.
The ability of the removing free radical of the composition containing light black huge marine algae extract of embodiment 1~11 is surveyed Examination, the results are shown in Table 2 for the inhibiting rate of free radical for above-mentioned composition.
Wherein, test philosophy is:According to free radical injury theory, the generation of free radical is to cause skin aging mainly former Cause.Therefore, if it is to evaluate one of the important indicator of anti-aging skin care product that the ability of free radical can be removed by, which having,.Hexichol is for bitter taste Acyl group free radical (DPPH) is a kind of free radical centered on nitrogen of stabilization, if tested material can remove it, then it represents that tested material Have the function of reducing the free radicals such as hydroxy radical, alkane free radical or peroxy radical.DPPH has strong absorption, second in 520nm Alcohol solution is dark purple, and after tested material is added, in 520nm, using spectrophotometric determination, it is removed DPPH and causes absorbance The case where reduction, can obtain the ability that tested material removes DPPH according to absorbance change.It is free that other remove superoxide anion, hydroxyl The experimental principle of base is same as above.
Test method is:The composition of Examples 1 to 10 is configured to mass volume ratio 1% respectively with dimethyl sulfoxide (DMSO) Sample solution is for use.
Er phenyl picryl Ben Jing ﹙ DPPH ﹚ of the above-mentioned sample solution of 2ml with 2ml molar concentrations for 100umol/L is taken respectively Solution is uniformly mixed and is placed in a test tube, and absorbance is measured under 517nm wavelength as Ai after standing 30min at room temperature;
It takes the above-mentioned sample solution of 2ml to be uniformly mixed with the dimethyl sulfoxide (DMSO) of 2ml respectively to be placed in a test tube, at room temperature Absorbance is measured under 517nm wavelength as Bi after standing 30min;
Take the dimethyl sulfoxide (DMSO) for the Er phenyl picryl Ben Jing ﹙ DPPH ﹚ solution and 2ml that 2ml molar concentrations are 100umol/L mixed Conjunction is uniformly placed in a test tube, and absorbance is measured under 517nm wavelength as Ci after standing 30min at room temperature;
Absorbance test is carried out using UV-1600 ultraviolet specrophotometers, wherein the calculation formula of inhibiting rate is:Ki% =[1-(Ai-Bi)/Ci] × 100%.
Table 2
Inhibiting rate (%)
Embodiment 1 82
Embodiment 2 79
Embodiment 3 81
Embodiment 4 86
Embodiment 5 85
Embodiment 6 87
Embodiment 7 76
Embodiment 8 62
Embodiment 9 59
Embodiment 10 61
Embodiment 11 75
To the composition containing light black huge marine algae extract of embodiment 1~11 for the active inhibiting rate of TYR enzyme into Row test, the results are shown in Table 3.
Wherein, test philosophy is:In the forming process of melanin, TYR enzyme plays the role of critical, fat Sour tyrosine generates DOPA quinone under the action of TYR enzyme, and DOPA quinone is under the oxidation of enzyme or non-enzymatic, by red Plain or colourless pigment is transformed into melanin, this process is the key step that melanin generates, and therefore, hinders or inhibit network ammonia The activity of sour enzyme can inhibit the generation of melanin in the first stage.Based on this, if having can inhibit TYR enzyme active Ability is to evaluate one of the important indicator of Skin whitening care cosmetics.
Test method:The composition of embodiment 1~11 is diluted to by mass body using the phosphate buffer of pH=6.8 respectively It is for use by taking supernatant to obtain sample solution after ultrasonic wave auxiliary dissolving 1h after accumulating than 1%.
The tyrosine and 1ml pH=6.8 that the molar concentration of the above-mentioned sample solution, 1mL that take 0.9mL respectively is 0.3M Phosphate buffer is uniformly mixed to be placed in 37 DEG C of thermostatic water baths and preheat 10 minutes, adds 0.1ml tyrosinase aqueous solutions (1.0mg/ml, mcllvains buffer solution), is sufficiently stirred, and absorbance is measured under 475nm wavelength after being reacted 15 minutes at 37 DEG C For Di;
The phosphate buffer for the tyrosine and 1.9ml pH=6.8 that the molar concentration of 1mL is 0.3M is taken to be uniformly mixed postposition It is preheated 10 minutes in 37 DEG C of thermostatic water baths, adding 0.1ml tyrosinases aqueous solution, (1.0mg/ml, mcllvains are buffered Liquid), it is sufficiently stirred, it is Ei to measure absorbance under 475nm wavelength after being reacted 15 minutes at 37 DEG C;
It takes the phosphate buffer for the tyrosine and 2ml pH=6.8 that the molar concentration of 1mL is 0.3M to be uniformly mixed to be placed on Preheat 25 minutes, be sufficiently stirred in 37 DEG C of thermostatic water baths, after under 475nm wavelength measure absorbance be Fi;
Absorbance test is carried out using UV-1600 ultraviolet specrophotometers, wherein the calculation formula of inhibiting rate is:Mi%- =(Ei-Di)/(Ei-Fi) × 100%.
Table 3
It is used to prepare the composition containing light black huge marine algae extract that embodiment 1~11 is prepared to obtain anti-aging Active white skin care solution, wherein anti-aging active white skin care solution includes shin moisturizer matrix and the above-mentioned group containing light black huge marine algae extract Object is closed, mass percentage of the above-mentioned composition in anti-aging active white skin care solution is as shown in table 4.Wherein, shin moisturizer matrix is pressed Mass fraction meter includes:6 parts of isopropyl palmitate, 0.6 part of tocopherol acetate, 10 parts of butanediol, 8 parts of glycerine, PEG-60 hydrogen Change 80 parts of 0.4 part of castor oil and water.
The anti-aging and whitening effect of above-mentioned anti-aging active white skin care solution are tested, the results are shown in Table 4.
When being tested, the female test person that 220 ages are 25~28 years old is chosen, is randomly divided into 11 groups, every group of 20 people. Using using the anti-aging active white skin care solution that is prepared of the present embodiment to carry out skin care processing after same face cleaning product, when use Between be 60 days, experimenter's every morning and at night respectively use the present embodiment anti-aging active white skin care solution carry out skin care, use Method is specially:It takes anti-aging active white skin care solution 2mL to be uniformly applied to skin of face, smears 5 minutes.On it should be noted that Other skin nursing situations for stating experimenter are consistent.
(1) anti-aging effects are tested:Callegarisoft plus are used before stating anti-aging active white skin care solution in use The spring probe of skinanalysis apparatus detects the test of the skin progress initial elasticity value of each experimenter, be averaged for 5 times For g1, anti-aging active white skin care solution is stated in use, and elasticity number test is carried out again to the skin of same test zone after 60 days, Be averaged as g for 5 times2, elasticity is rated g2/g1, the numerical value of elasticity grading is bigger to illustrate that skin elasticity increase is more apparent. Every group test elasticity grading removal two highests and two it is minimum after be averaged.
(2) whitening effect is tested:Anti-aging whitening and skin-protecting is stated using MEXAMETER MX18 skin pigments instrument in use It the previous day of liquid and is tested using the dermal melanin content after above-mentioned anti-aging active white skin care solution 60 days, test condition For:Test temperature is 25 DEG C, ambient humidity 50%.
The calculation formula of melanin reduced rate is:Pi%=(Li-Ni)/Li × 100%, wherein Li is to use anti-aging The melanin content of active white skin care solution the previous day, Ni are using the dermal melanin content after anti-aging active white skin care solution 60 days. Every group of melanin reduced rate for testing remove two highests and two it is minimum after be averaged.
Table 4
Each technical characteristic of embodiment described above can be combined arbitrarily, to keep description succinct, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, it is all considered to be the range of this specification record.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention Range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.

Claims (9)

1. a kind of composition containing light black huge marine algae extract, which is characterized in that including the first component and the second component;
Wherein, first component includes according to the mass fraction:6 parts~10 parts of light black huge marine algae extract, 3 parts~6 parts Dogfish oil and 1~3 part of Barley Greeg;
Second component includes according to the mass fraction:4 parts~8 parts of Hydrolyzed Collagen and 1 part~3 parts of water soluble pearl egg In vain;
The mass ratio of first component and second component is " 12~18 ":" 4~8 ".
2. the composition according to claim 1 containing light black huge marine algae extract, which is characterized in that press mass fraction Meter, first component further includes 3 parts~6 parts of angelica extract, 2 parts~5 parts of mulberries extract and 1 part~3 parts of bear Fruit glycosides.
3. the composition according to claim 2 containing light black huge marine algae extract, which is characterized in that press mass fraction Meter, first component further includes 3 parts~5 parts of angelica extract, 3 parts~4 parts of mulberries extract and 2 parts~3 parts of bear Fruit glycosides.
4. the composition according to claim 1 containing light black huge marine algae extract, which is characterized in that described containing light black The composition of huge marine algae extract further includes third component, the third component in water, propylene glycol and glycerine at least one Kind.
5. the composition according to claim 4 containing light black huge marine algae extract, which is characterized in that first component Mass ratio with the third component is " 10~20 ":" 10~100 ".
6. the composition according to claim 1 containing light black huge marine algae extract, which is characterized in that first component Mass ratio with second component is " 15~17 ":" 4~6 ".
7. a kind of anti-aging Skin whitening care cosmetics, which is characterized in that contain including such as claim 1~6 any one of them light black The composition of huge marine algae extract.
8. anti-aging Skin whitening care cosmetics according to claim 7, which is characterized in that the agent of the anti-aging Skin whitening care cosmetics Type is creme, lotion, aqua or facial mask.
9. anti-aging Skin whitening care cosmetics according to claim 7, which is characterized in that described to contain light black huge marine algae extract Mass percentage of the composition in the anti-aging Skin whitening care cosmetics be 0.6%~10%.
CN201810311061.8A 2018-04-09 2018-04-09 Composition and anti-aging Skin whitening care cosmetics containing light black huge marine algae extract Withdrawn CN108324667A (en)

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CN108785207A (en) * 2018-08-10 2018-11-13 广州碧雅医疗保健科技有限公司 A kind of anti-aging of the ingredient containing Chinese medicine compound prescription is preserved youthful looks skin care compositions and skin care item
CN109875933A (en) * 2019-03-28 2019-06-14 广州市富宝日用化工有限公司 Compact eye cream cosmetics of a kind of U.S. pupil and preparation method thereof
CN116889540A (en) * 2023-08-02 2023-10-17 露乐健康科技股份有限公司 Bionic hippopotamus sweat composition and application thereof in sun-screening products

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CN105012185A (en) * 2015-07-28 2015-11-04 广州市科能化妆品科研有限公司 Cosmetic and application of perilla extract in cosmetic as transdermal penetration enhancer
CN107648178A (en) * 2017-11-13 2018-02-02 梁兆寇 Traditional Chinese medicine mask without chemical preservative

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CN104434636A (en) * 2014-11-14 2015-03-25 成都鹏翔生物科技有限公司 Cinnamomum glanduliferum seed oil-containing lotion capable of moisturizing and caring skin and preparation method thereof
CN105012185A (en) * 2015-07-28 2015-11-04 广州市科能化妆品科研有限公司 Cosmetic and application of perilla extract in cosmetic as transdermal penetration enhancer
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108785207A (en) * 2018-08-10 2018-11-13 广州碧雅医疗保健科技有限公司 A kind of anti-aging of the ingredient containing Chinese medicine compound prescription is preserved youthful looks skin care compositions and skin care item
CN109875933A (en) * 2019-03-28 2019-06-14 广州市富宝日用化工有限公司 Compact eye cream cosmetics of a kind of U.S. pupil and preparation method thereof
CN116889540A (en) * 2023-08-02 2023-10-17 露乐健康科技股份有限公司 Bionic hippopotamus sweat composition and application thereof in sun-screening products
CN116889540B (en) * 2023-08-02 2024-01-30 露乐健康科技股份有限公司 Bionic hippopotamus sweat composition and application thereof in sun-screening products

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